EPHB2_HUMAN
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor. May be involved in the regulation of platelet activation and blood coagulation (PubMed). [View more on UniProt]
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Position | Amino acid | Mutation | Disease | Overlap with binding region |
---|---|---|---|---|
199 | Arg | His | Prostatecancer(PC) | - |
279 | Ala | Ser | Prostatecancer(PC) | - |
650 | Val | Ala | Prostatecancer(PC) | - |
679 | His | Asn | Prostatecancer(PC) | - |
883 | Met | Val | Prostatecancer(PC) | - |
909 | Ile | Met | Prostatecancer(PC) | - |
745 | Arg | Cys | Bleedingdisorder,platelet-type,22(BDPLT22) | - |
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in EPHB2_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 33.0097 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 33.0097 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 32.0388 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 23.3010 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 23.3010 | 5 | yes |
GO:0019900 | kinase binding | 23.3010 | 4 | no |
GO:0005524 | ATP binding | 22.3301 | 5 | yes |
GO:0016301 | kinase activity | 22.3301 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 22.3301 | 4 | yes |
GO:0019901 | protein kinase binding | 21.3592 | 5 | no |
GO:0046872 | metal ion binding | 20.3883 | 4 | no |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 19.4175 | 4 | yes |
GO:0004713 | protein tyrosine kinase activity | 14.5631 | 4 | yes |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity | 6.7961 | 5 | yes |
GO:0019199 | transmembrane receptor protein kinase activity | 6.7961 | 4 | yes |
GO:0005003 | ephrin receptor activity | 4.8544 | 6 | yes |
GO:0005005 | transmembrane-ephrin receptor activity | 4.8544 | 7 | yes |
GO:0001540 | amyloid-beta binding | 3.8835 | 4 | yes |
GO:0008046 | axon guidance receptor activity | 3.8835 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in EPHB2_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 66.9903 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 58.2524 | 4 | yes |
GO:0010646 | regulation of cell communication | 56.3107 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 53.3981 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 53.3981 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 48.5437 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 48.5437 | 4 | yes |
GO:0009966 | regulation of signal transduction | 48.5437 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 45.6311 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 45.6311 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 43.6893 | 5 | yes |
GO:0030030 | cell projection organization | 42.7184 | 4 | yes |
GO:0051049 | regulation of transport | 40.7767 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 39.8058 | 5 | yes |
GO:1902531 | regulation of intracellular signal transduction | 39.8058 | 5 | yes |
GO:0010468 | regulation of gene expression | 38.8350 | 5 | yes |
GO:0022607 | cellular component assembly | 37.8641 | 4 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 36.8932 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 36.8932 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 36.8932 | 5 | yes |
GO:0051130 | positive regulation of cellular component organization | 34.9515 | 5 | yes |
GO:0071310 | cellular response to organic substance | 34.9515 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 34.9515 | 4 | yes |
GO:0031344 | regulation of cell projection organization | 34.9515 | 5 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 33.9806 | 6 | yes |
GO:0033043 | regulation of organelle organization | 32.0388 | 5 | no |
GO:0006996 | organelle organization | 32.0388 | 4 | no |
GO:0023056 | positive regulation of signaling | 32.0388 | 4 | yes |
GO:0008104 | protein localization | 31.0680 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 31.0680 | 6 | no |
GO:0010647 | positive regulation of cell communication | 31.0680 | 5 | yes |
GO:0048584 | positive regulation of response to stimulus | 31.0680 | 4 | no |
GO:0016192 | vesicle-mediated transport | 31.0680 | 4 | yes |
GO:0031399 | regulation of protein modification process | 31.0680 | 6 | yes |
GO:0043085 | positive regulation of catalytic activity | 31.0680 | 4 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 30.0971 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 30.0971 | 6 | yes |
GO:0042325 | regulation of phosphorylation | 30.0971 | 7 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 29.1262 | 4 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 28.1553 | 4 | yes |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 28.1553 | 5 | yes |
GO:0036211 | protein modification process | 28.1553 | 4 | yes |
GO:0043412 | macromolecule modification | 28.1553 | 4 | yes |
GO:0044087 | regulation of cellular component biogenesis | 28.1553 | 4 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 27.1845 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 27.1845 | 5 | no |
GO:0051493 | regulation of cytoskeleton organization | 27.1845 | 6 | no |
GO:0001932 | regulation of protein phosphorylation | 26.2136 | 7 | yes |
GO:0010941 | regulation of cell death | 26.2136 | 4 | no |
GO:0016310 | phosphorylation | 26.2136 | 5 | yes |
GO:0031175 | neuron projection development | 26.2136 | 6 | yes |
GO:0042127 | regulation of cell population proliferation | 26.2136 | 4 | yes |
GO:0051050 | positive regulation of transport | 25.2427 | 4 | yes |
GO:0051129 | negative regulation of cellular component organization | 25.2427 | 5 | yes |
GO:2000145 | regulation of cell motility | 25.2427 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 25.2427 | 4 | yes |
GO:0010562 | positive regulation of phosphorus metabolic process | 25.2427 | 6 | yes |
GO:0051336 | regulation of hydrolase activity | 25.2427 | 4 | no |
GO:0032970 | regulation of actin filament-based process | 25.2427 | 4 | no |
GO:0030155 | regulation of cell adhesion | 25.2427 | 4 | yes |
GO:0045595 | regulation of cell differentiation | 25.2427 | 4 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 25.2427 | 7 | yes |
GO:0010243 | response to organonitrogen compound | 24.2718 | 4 | yes |
GO:0031401 | positive regulation of protein modification process | 24.2718 | 7 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 24.2718 | 5 | yes |
GO:0042981 | regulation of apoptotic process | 24.2718 | 6 | no |
GO:0043067 | regulation of programmed cell death | 24.2718 | 5 | no |
GO:0030334 | regulation of cell migration | 24.2718 | 5 | yes |
GO:0042327 | positive regulation of phosphorylation | 24.2718 | 8 | yes |
GO:0051094 | positive regulation of developmental process | 23.3010 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.3010 | 5 | no |
GO:0010975 | regulation of neuron projection development | 23.3010 | 7 | yes |
GO:0032956 | regulation of actin cytoskeleton organization | 23.3010 | 5 | no |
GO:1902903 | regulation of supramolecular fiber organization | 23.3010 | 5 | no |
GO:0060341 | regulation of cellular localization | 22.3301 | 4 | yes |
GO:0080134 | regulation of response to stress | 22.3301 | 4 | yes |
GO:0006468 | protein phosphorylation | 22.3301 | 5 | yes |
GO:0009889 | regulation of biosynthetic process | 22.3301 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 22.3301 | 5 | no |
GO:0007010 | cytoskeleton organization | 22.3301 | 5 | no |
GO:0031346 | positive regulation of cell projection organization | 22.3301 | 6 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 21.3592 | 4 | yes |
GO:0051338 | regulation of transferase activity | 21.3592 | 4 | yes |
GO:0002684 | positive regulation of immune system process | 21.3592 | 4 | yes |
GO:2000026 | regulation of multicellular organismal development | 21.3592 | 4 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 21.3592 | 6 | no |
GO:0032880 | regulation of protein localization | 21.3592 | 5 | yes |
GO:0034330 | cell junction organization | 21.3592 | 4 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 21.3592 | 5 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.3883 | 5 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 20.3883 | 8 | no |
GO:0060627 | regulation of vesicle-mediated transport | 20.3883 | 4 | no |
GO:0071702 | organic substance transport | 20.3883 | 4 | no |
GO:0071705 | nitrogen compound transport | 20.3883 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 20.3883 | 5 | no |
GO:0051252 | regulation of RNA metabolic process | 20.3883 | 5 | no |
GO:0032990 | cell part morphogenesis | 20.3883 | 4 | yes |
GO:0043549 | regulation of kinase activity | 20.3883 | 5 | yes |
GO:0048585 | negative regulation of response to stimulus | 20.3883 | 4 | yes |
GO:0048858 | cell projection morphogenesis | 20.3883 | 5 | yes |
GO:0050776 | regulation of immune response | 19.4175 | 4 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 19.4175 | 5 | yes |
GO:0051347 | positive regulation of transferase activity | 19.4175 | 5 | yes |
GO:0060284 | regulation of cell development | 19.4175 | 5 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 19.4175 | 4 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 19.4175 | 6 | yes |
GO:0022604 | regulation of cell morphogenesis | 19.4175 | 5 | yes |
GO:0051248 | negative regulation of protein metabolic process | 18.4466 | 6 | yes |
GO:2000147 | positive regulation of cell motility | 18.4466 | 5 | yes |
GO:0010628 | positive regulation of gene expression | 18.4466 | 6 | yes |
GO:0030335 | positive regulation of cell migration | 18.4466 | 6 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 18.4466 | 5 | yes |
GO:0032101 | regulation of response to external stimulus | 18.4466 | 4 | yes |
GO:0033674 | positive regulation of kinase activity | 18.4466 | 6 | yes |
GO:0040017 | positive regulation of locomotion | 18.4466 | 4 | yes |
GO:0050865 | regulation of cell activation | 17.4757 | 4 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 17.4757 | 4 | yes |
GO:0071417 | cellular response to organonitrogen compound | 17.4757 | 4 | yes |
GO:1901699 | cellular response to nitrogen compound | 17.4757 | 4 | yes |
GO:0008284 | positive regulation of cell population proliferation | 17.4757 | 5 | yes |
GO:0034762 | regulation of transmembrane transport | 17.4757 | 4 | yes |
GO:0043269 | regulation of ion transport | 17.4757 | 5 | yes |
GO:0043408 | regulation of MAPK cascade | 17.4757 | 6 | yes |
GO:0045859 | regulation of protein kinase activity | 17.4757 | 6 | yes |
GO:0048013 | ephrin receptor signaling pathway | 17.4757 | 6 | yes |
GO:0048812 | neuron projection morphogenesis | 17.4757 | 7 | yes |
GO:0051056 | regulation of small GTPase mediated signal transduction | 16.5049 | 6 | yes |
GO:0051249 | regulation of lymphocyte activation | 16.5049 | 5 | yes |
GO:0002694 | regulation of leukocyte activation | 16.5049 | 4 | yes |
GO:0010648 | negative regulation of cell communication | 16.5049 | 5 | yes |
GO:0023057 | negative regulation of signaling | 16.5049 | 4 | yes |
GO:0034765 | regulation of ion transmembrane transport | 16.5049 | 5 | yes |
GO:0045597 | positive regulation of cell differentiation | 16.5049 | 5 | yes |
GO:0051093 | negative regulation of developmental process | 15.5340 | 4 | yes |
GO:0061024 | membrane organization | 14.5631 | 4 | yes |
GO:1903829 | positive regulation of protein localization | 14.5631 | 5 | yes |
GO:0009968 | negative regulation of signal transduction | 14.5631 | 5 | yes |
GO:0010720 | positive regulation of cell development | 14.5631 | 6 | yes |
GO:0050867 | positive regulation of cell activation | 13.5922 | 5 | yes |
GO:0051960 | regulation of nervous system development | 13.5922 | 5 | yes |
GO:0060491 | regulation of cell projection assembly | 13.5922 | 5 | yes |
GO:0097485 | neuron projection guidance | 13.5922 | 7 | yes |
GO:1901652 | response to peptide | 13.5922 | 4 | yes |
GO:1904062 | regulation of cation transmembrane transport | 13.5922 | 6 | yes |
GO:0007411 | axon guidance | 13.5922 | 8 | yes |
GO:0010629 | negative regulation of gene expression | 13.5922 | 6 | yes |
GO:0018193 | peptidyl-amino acid modification | 13.5922 | 5 | yes |
GO:0031347 | regulation of defense response | 13.5922 | 5 | yes |
GO:0031400 | negative regulation of protein modification process | 13.5922 | 7 | yes |
GO:0033993 | response to lipid | 13.5922 | 4 | yes |
GO:0050767 | regulation of neurogenesis | 13.5922 | 6 | yes |
GO:0051051 | negative regulation of transport | 12.6214 | 4 | yes |
GO:0051251 | positive regulation of lymphocyte activation | 12.6214 | 6 | yes |
GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 12.6214 | 6 | yes |
GO:0002696 | positive regulation of leukocyte activation | 12.6214 | 5 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 12.6214 | 6 | yes |
GO:0042326 | negative regulation of phosphorylation | 12.6214 | 8 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 12.6214 | 7 | yes |
GO:0050807 | regulation of synapse organization | 11.6505 | 5 | yes |
GO:0001817 | regulation of cytokine production | 11.6505 | 4 | yes |
GO:0018108 | peptidyl-tyrosine phosphorylation | 11.6505 | 6 | yes |
GO:0018212 | peptidyl-tyrosine modification | 11.6505 | 6 | yes |
GO:0031345 | negative regulation of cell projection organization | 11.6505 | 6 | yes |
GO:0043270 | positive regulation of ion transport | 11.6505 | 5 | yes |
GO:0045596 | negative regulation of cell differentiation | 11.6505 | 5 | yes |
GO:1901653 | cellular response to peptide | 10.6796 | 5 | yes |
GO:0001933 | negative regulation of protein phosphorylation | 10.6796 | 8 | yes |
GO:0034329 | cell junction assembly | 10.6796 | 5 | yes |
GO:0034764 | positive regulation of transmembrane transport | 10.6796 | 5 | yes |
GO:0034767 | positive regulation of ion transmembrane transport | 10.6796 | 6 | yes |
GO:0045216 | cell-cell junction organization | 10.6796 | 5 | yes |
GO:0050770 | regulation of axonogenesis | 10.6796 | 5 | yes |
GO:0050773 | regulation of dendrite development | 9.7087 | 4 | yes |
GO:0050890 | cognition | 9.7087 | 4 | yes |
GO:0051962 | positive regulation of nervous system development | 9.7087 | 5 | yes |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 9.7087 | 7 | yes |
GO:0071396 | cellular response to lipid | 9.7087 | 5 | yes |
GO:1901888 | regulation of cell junction assembly | 9.7087 | 5 | yes |
GO:1904064 | positive regulation of cation transmembrane transport | 9.7087 | 7 | yes |
GO:0007162 | negative regulation of cell adhesion | 9.7087 | 5 | yes |
GO:0010769 | regulation of cell morphogenesis involved in differentiation | 9.7087 | 6 | yes |
GO:0010976 | positive regulation of neuron projection development | 9.7087 | 7 | yes |
GO:0010977 | negative regulation of neuron projection development | 9.7087 | 7 | yes |
GO:0022898 | regulation of transmembrane transporter activity | 9.7087 | 4 | yes |
GO:0032412 | regulation of ion transmembrane transporter activity | 9.7087 | 5 | yes |
GO:0043086 | negative regulation of catalytic activity | 9.7087 | 4 | yes |
GO:0046578 | regulation of Ras protein signal transduction | 9.7087 | 7 | yes |
GO:0050769 | positive regulation of neurogenesis | 9.7087 | 6 | yes |
GO:1902532 | negative regulation of intracellular signal transduction | 8.7379 | 6 | yes |
GO:1905475 | regulation of protein localization to membrane | 8.7379 | 6 | yes |
GO:0007409 | axonogenesis | 8.7379 | 8 | yes |
GO:0010770 | positive regulation of cell morphogenesis involved in differentiation | 8.7379 | 7 | yes |
GO:0070663 | regulation of leukocyte proliferation | 7.7670 | 5 | yes |
GO:0099175 | regulation of postsynapse organization | 7.7670 | 6 | yes |
GO:0106027 | neuron projection organization | 7.7670 | 6 | yes |
GO:0001819 | positive regulation of cytokine production | 7.7670 | 5 | yes |
GO:0007612 | learning | 7.7670 | 4 | yes |
GO:2001257 | regulation of cation channel activity | 7.7670 | 6 | yes |
GO:0051961 | negative regulation of nervous system development | 6.7961 | 5 | yes |
GO:1903034 | regulation of response to wounding | 6.7961 | 5 | yes |
GO:1905477 | positive regulation of protein localization to membrane | 6.7961 | 6 | yes |
GO:0007399 | nervous system development | 6.7961 | 4 | yes |
GO:2001259 | positive regulation of cation channel activity | 6.7961 | 6 | yes |
GO:0010721 | negative regulation of cell development | 6.7961 | 6 | yes |
GO:0032410 | negative regulation of transporter activity | 6.7961 | 4 | yes |
GO:0032411 | positive regulation of transporter activity | 6.7961 | 4 | yes |
GO:0032413 | negative regulation of ion transmembrane transporter activity | 6.7961 | 5 | yes |
GO:0032414 | positive regulation of ion transmembrane transporter activity | 6.7961 | 5 | yes |
GO:0032944 | regulation of mononuclear cell proliferation | 6.7961 | 6 | yes |
GO:0034763 | negative regulation of transmembrane transport | 6.7961 | 5 | yes |
GO:0034766 | negative regulation of ion transmembrane transport | 6.7961 | 6 | yes |
GO:0043271 | negative regulation of ion transport | 6.7961 | 5 | yes |
GO:0050670 | regulation of lymphocyte proliferation | 6.7961 | 6 | yes |
GO:0050768 | negative regulation of neurogenesis | 6.7961 | 6 | yes |
GO:0050771 | negative regulation of axonogenesis | 5.8252 | 6 | yes |
GO:0051348 | negative regulation of transferase activity | 5.8252 | 5 | yes |
GO:0060998 | regulation of dendritic spine development | 5.8252 | 4 | yes |
GO:0071219 | cellular response to molecule of bacterial origin | 5.8252 | 4 | yes |
GO:0071222 | cellular response to lipopolysaccharide | 5.8252 | 5 | yes |
GO:0097061 | dendritic spine organization | 5.8252 | 5 | yes |
GO:0099173 | postsynapse organization | 5.8252 | 4 | yes |
GO:0099537 | trans-synaptic signaling | 5.8252 | 4 | yes |
GO:0002237 | response to molecule of bacterial origin | 5.8252 | 4 | yes |
GO:1904063 | negative regulation of cation transmembrane transport | 5.8252 | 7 | yes |
GO:1904375 | regulation of protein localization to cell periphery | 5.8252 | 6 | yes |
GO:1904645 | response to amyloid-beta | 5.8252 | 5 | yes |
GO:1904646 | cellular response to amyloid-beta | 5.8252 | 6 | yes |
GO:2001258 | negative regulation of cation channel activity | 5.8252 | 6 | yes |
GO:0032496 | response to lipopolysaccharide | 5.8252 | 4 | yes |
GO:0051489 | regulation of filopodium assembly | 4.8544 | 7 | yes |
GO:0051963 | regulation of synapse assembly | 4.8544 | 6 | yes |
GO:0061001 | regulation of dendritic spine morphogenesis | 4.8544 | 5 | yes |
GO:0061041 | regulation of wound healing | 4.8544 | 6 | yes |
GO:0070373 | negative regulation of ERK1 and ERK2 cascade | 4.8544 | 8 | yes |
GO:0070665 | positive regulation of leukocyte proliferation | 4.8544 | 6 | yes |
GO:0071709 | membrane assembly | 4.8544 | 5 | yes |
GO:1900271 | regulation of long-term synaptic potentiation | 4.8544 | 4 | yes |
GO:1901890 | positive regulation of cell junction assembly | 4.8544 | 6 | yes |
GO:0001818 | negative regulation of cytokine production | 4.8544 | 5 | yes |
GO:1903076 | regulation of protein localization to plasma membrane | 4.8544 | 7 | yes |
GO:0006469 | negative regulation of protein kinase activity | 4.8544 | 7 | yes |
GO:0007043 | cell-cell junction assembly | 4.8544 | 6 | yes |
GO:0021952 | central nervous system projection neuron axonogenesis | 4.8544 | 10 | yes |
GO:0021955 | central nervous system neuron axonogenesis | 4.8544 | 9 | yes |
GO:0033673 | negative regulation of kinase activity | 4.8544 | 6 | yes |
GO:0043409 | negative regulation of MAPK cascade | 4.8544 | 7 | yes |
GO:0048168 | regulation of neuronal synaptic plasticity | 4.8544 | 4 | yes |
GO:0048169 | regulation of long-term neuronal synaptic plasticity | 4.8544 | 5 | yes |
GO:0048814 | regulation of dendrite morphogenesis | 4.8544 | 5 | yes |
GO:0050775 | positive regulation of dendrite morphogenesis | 3.8835 | 6 | yes |
GO:0050806 | positive regulation of synaptic transmission | 3.8835 | 5 | yes |
GO:0050864 | regulation of B cell activation | 3.8835 | 6 | yes |
GO:0060997 | dendritic spine morphogenesis | 3.8835 | 6 | yes |
GO:0060999 | positive regulation of dendritic spine development | 3.8835 | 5 | yes |
GO:0099601 | regulation of neurotransmitter receptor activity | 3.8835 | 4 | yes |
GO:1903555 | regulation of tumor necrosis factor superfamily cytokine production | 3.8835 | 5 | yes |
GO:1903557 | positive regulation of tumor necrosis factor superfamily cytokine production | 3.8835 | 6 | yes |
GO:0002697 | regulation of immune effector process | 3.8835 | 4 | yes |
GO:0032680 | regulation of tumor necrosis factor production | 3.8835 | 6 | yes |
GO:0032760 | positive regulation of tumor necrosis factor production | 3.8835 | 7 | yes |
GO:0050818 | regulation of coagulation | 2.9126 | 4 | yes |
GO:0050871 | positive regulation of B cell activation | 2.9126 | 7 | yes |
GO:0051058 | negative regulation of small GTPase mediated signal transduction | 2.9126 | 7 | yes |
GO:0061003 | positive regulation of dendritic spine morphogenesis | 2.9126 | 6 | yes |
GO:0099545 | trans-synaptic signaling by trans-synaptic complex | 2.9126 | 5 | yes |
GO:0099550 | trans-synaptic signaling, modulating synaptic transmission | 2.9126 | 5 | yes |
GO:0099557 | trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission | 2.9126 | 6 | yes |
GO:0106030 | neuron projection fasciculation | 2.9126 | 7 | yes |
GO:1900273 | positive regulation of long-term synaptic potentiation | 2.9126 | 5 | yes |
GO:1903078 | positive regulation of protein localization to plasma membrane | 2.9126 | 7 | yes |
GO:0002699 | positive regulation of immune effector process | 2.9126 | 5 | yes |
GO:1904377 | positive regulation of protein localization to cell periphery | 2.9126 | 6 | yes |
GO:1904892 | regulation of receptor signaling pathway via STAT | 2.9126 | 5 | yes |
GO:2000272 | negative regulation of signaling receptor activity | 2.9126 | 4 | yes |
GO:2000310 | regulation of NMDA receptor activity | 2.9126 | 5 | yes |
GO:0007413 | axonal fasciculation | 2.9126 | 4 | yes |
GO:0030888 | regulation of B cell proliferation | 2.9126 | 7 | yes |
GO:0031290 | retinal ganglion cell axon guidance | 2.9126 | 9 | yes |
GO:0032946 | positive regulation of mononuclear cell proliferation | 2.9126 | 7 | yes |
GO:0042113 | B cell activation | 2.9126 | 4 | yes |
GO:0046425 | regulation of receptor signaling pathway via JAK-STAT | 2.9126 | 6 | yes |
GO:0046580 | negative regulation of Ras protein signal transduction | 2.9126 | 8 | yes |
GO:0050671 | positive regulation of lymphocyte proliferation | 2.9126 | 7 | yes |
GO:0050795 | regulation of behavior | 1.9417 | 4 | yes |
GO:0051965 | positive regulation of synapse assembly | 1.9417 | 6 | yes |
GO:0071679 | commissural neuron axon guidance | 1.9417 | 9 | yes |
GO:0090596 | sensory organ morphogenesis | 1.9417 | 4 | yes |
GO:0097104 | postsynaptic membrane assembly | 1.9417 | 6 | yes |
GO:0106028 | neuron projection retraction | 1.9417 | 7 | yes |
GO:0120192 | tight junction assembly | 1.9417 | 7 | yes |
GO:0120193 | tight junction organization | 1.9417 | 6 | yes |
GO:1900015 | regulation of cytokine production involved in inflammatory response | 1.9417 | 5 | yes |
GO:1900016 | negative regulation of cytokine production involved in inflammatory response | 1.9417 | 6 | yes |
GO:0001655 | urogenital system development | 1.9417 | 4 | yes |
GO:0001941 | postsynaptic membrane organization | 1.9417 | 5 | yes |
GO:1903365 | regulation of fear response | 1.9417 | 4 | yes |
GO:0002637 | regulation of immunoglobulin production | 1.9417 | 6 | yes |
GO:0002639 | positive regulation of immunoglobulin production | 1.9417 | 7 | yes |
GO:0002700 | regulation of production of molecular mediator of immune response | 1.9417 | 5 | yes |
GO:0002702 | positive regulation of production of molecular mediator of immune response | 1.9417 | 6 | yes |
GO:0002819 | regulation of adaptive immune response | 1.9417 | 5 | yes |
GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 1.9417 | 6 | yes |
GO:1904782 | negative regulation of NMDA glutamate receptor activity | 1.9417 | 5 | yes |
GO:1904783 | positive regulation of NMDA glutamate receptor activity | 1.9417 | 5 | yes |
GO:2000273 | positive regulation of signaling receptor activity | 1.9417 | 4 | yes |
GO:2000316 | regulation of T-helper 17 type immune response | 1.9417 | 7 | yes |
GO:2000822 | regulation of behavioral fear response | 1.9417 | 5 | yes |
GO:0021535 | cell migration in hindbrain | 1.9417 | 4 | yes |
GO:0021631 | optic nerve morphogenesis | 1.9417 | 4 | yes |
GO:0021934 | hindbrain tangential cell migration | 1.9417 | 5 | yes |
GO:0030193 | regulation of blood coagulation | 1.9417 | 4 | yes |
GO:0030890 | positive regulation of B cell proliferation | 1.9417 | 8 | yes |
GO:0031915 | positive regulation of synaptic plasticity | 1.9417 | 4 | yes |
GO:0042472 | inner ear morphogenesis | 1.9417 | 4 | yes |
GO:0048170 | positive regulation of long-term neuronal synaptic plasticity | 1.9417 | 6 | yes |
GO:0048592 | eye morphogenesis | 1.9417 | 5 | yes |
GO:0048593 | camera-type eye morphogenesis | 1.9417 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in EPHB2_HUMAN |
---|---|---|---|---|
DOID:0050686 | organ system cancer | 2.9126 | 3 | yes |
DOID:193 | reproductive organ cancer | 2.9126 | 4 | yes |
DOID:114 | heart disease | 2.9126 | 3 | no |
DOID:10283 | prostate cancer | 1.9417 | 6 | yes |
DOID:3856 | male reproductive organ cancer | 1.9417 | 5 | yes |
DOID:0050700 | cardiomyopathy | 1.9417 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 1.9417 | 5 | no |
DOID:2843 | long QT syndrome | 1.9417 | 6 | no |
DOID:0060038 | specific developmental disorder | 1.9417 | 3 | no |
DOID:0060307 | autosomal dominant intellectual developmental disorder | 1.9417 | 5 | no |
DOID:1059 | intellectual disability | 1.9417 | 4 | no |
DOID:0111962 | combined immunodeficiency | 1.9417 | 4 | no |
DOID:612 | primary immunodeficiency disease | 1.9417 | 3 | no |
DOID:627 | severe combined immunodeficiency | 1.9417 | 5 | no |
DOID:2476 | hereditary spastic paraplegia | 1.9417 | 5 | no |
DOID:331 | central nervous system disease | 1.9417 | 3 | no |
DOID:607 | paraplegia | 1.9417 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
AFAD_HUMAN | [view interactions] | Low throughput | no | yes |
PICK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ABL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TIAM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EPHA4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NU153_HUMAN | [view interactions] | Low throughput | no | yes |
EFNB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PAXI_HUMAN | [view interactions] | Low throughput | no | yes |
EFNA5_HUMAN | [view interactions] | Low throughput | no | yes |
EPHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EPHA2_HUMAN | [view interactions] | Low throughput | no | no |
PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PPAC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RASA1_HUMAN | [view interactions] | Low throughput | no | yes |
RYK_HUMAN | [view interactions] | Low throughput | no | no |
ITSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HMMR_HUMAN | [view interactions] | Low throughput | no | yes |
SPSB4_HUMAN | [view interactions] | Low throughput | no | no |
SPSB1_HUMAN | [view interactions] | Low throughput | no | no |
RN186_HUMAN | [view interactions] | Low throughput | no | no |
EPHA3_HUMAN | [view interactions] | Low throughput | no | yes |
STK26_HUMAN | [view interactions] | Low throughput | no | no |
CRK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
YES_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GIT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NCK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TSN15_HUMAN | [view interactions] | High throughput | no | yes |
TRI54_HUMAN | [view interactions] | High throughput | no | no |
EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CSF1R_HUMAN | [view interactions] | High throughput | no | yes |
KPSH2_HUMAN | [view interactions] | High throughput | no | no |
EPHA6_HUMAN | [view interactions] | High throughput | no | no |
MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EPHB1_HUMAN | [view interactions] | High throughput | no | no |
TM9S3_HUMAN | [view interactions] | High throughput | no | yes |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
ZDHC6_HUMAN | [view interactions] | High throughput | no | no |
RAE1L_HUMAN | [view interactions] | High throughput | no | no |
EPHB3_HUMAN | [view interactions] | High throughput | no | yes |
FANCI_HUMAN | [view interactions] | High throughput | no | yes |
OZF_HUMAN | [view interactions] | High throughput | no | yes |
ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBSP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BAF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MDN1_HUMAN | [view interactions] | High throughput | no | no |
HACD3_HUMAN | [view interactions] | High throughput | no | yes |
TRM2A_HUMAN | [view interactions] | High throughput | no | yes |
NTPCR_HUMAN | [view interactions] | High throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCAT1_HUMAN | [view interactions] | High throughput | no | yes |
PDIP3_HUMAN | [view interactions] | High throughput | no | no |
EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S39A7_HUMAN | [view interactions] | High throughput | no | yes |
DYH10_HUMAN | [view interactions] | High throughput | no | no |
RS29_HUMAN | [view interactions] | High throughput | no | yes |
RBL1_HUMAN | [view interactions] | High throughput | no | yes |
TP4A2_HUMAN | [view interactions] | High throughput | no | yes |
MET_HUMAN | [view interactions] | High throughput | no | yes |
MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
US6NL_HUMAN | [view interactions] | High throughput | no | yes |
M21D2_HUMAN | [view interactions] | High throughput | no | yes |
OCLN_HUMAN | [view interactions] | High throughput | no | no |
GORS2_HUMAN | [view interactions] | High throughput | no | yes |
NISCH_HUMAN | [view interactions] | High throughput | no | yes |
PI4KA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GOPC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GRIN3_HUMAN | [view interactions] | High throughput | no | yes |
SC23B_HUMAN | [view interactions] | High throughput | no | yes |
NUD19_HUMAN | [view interactions] | High throughput | no | no |
BRK1_HUMAN | [view interactions] | High throughput | no | no |
SEP10_HUMAN | [view interactions] | High throughput | no | yes |
P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
TB10B_HUMAN | [view interactions] | High throughput | no | no |
ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACOT2_HUMAN | [view interactions] | High throughput | no | yes |
SCAM1_HUMAN | [view interactions] | High throughput | no | no |
MERL_HUMAN | [view interactions] | High throughput | no | yes |
ROCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EPS8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
F1711_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WASF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC24A_HUMAN | [view interactions] | High throughput | no | no |
DIP2A_HUMAN | [view interactions] | High throughput | no | no |
UACA_HUMAN | [view interactions] | High throughput | no | yes |
SEPT3_HUMAN | [view interactions] | High throughput | no | no |
STIM1_HUMAN | [view interactions] | High throughput | no | yes |
SRGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LRBA_HUMAN | [view interactions] | High throughput | no | yes |
SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SEPT9_HUMAN | [view interactions] | High throughput | no | no |
ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M4K4_HUMAN | [view interactions] | High throughput | no | yes |
CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTN13_HUMAN | [view interactions] | High throughput | no | yes |
GCP60_HUMAN | [view interactions] | High throughput | no | yes |
PKHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FERM2_HUMAN | [view interactions] | High throughput | no | yes |
FCHO2_HUMAN | [view interactions] | High throughput | no | yes |
PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COPE_HUMAN | [view interactions] | High throughput | no | yes |
PHAR4_HUMAN | [view interactions] | High throughput | no | yes |
YKT6_HUMAN | [view interactions] | High throughput | no | yes |
ZFY16_HUMAN | [view interactions] | High throughput | no | yes |
SEPT8_HUMAN | [view interactions] | High throughput | no | no |
WASF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC24B_HUMAN | [view interactions] | High throughput | no | yes |
ADDB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAPH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NUMB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LSR_HUMAN | [view interactions] | High throughput | no | yes |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MARK3_HUMAN | [view interactions] | High throughput | no | yes |
NIBA2_HUMAN | [view interactions] | High throughput | no | no |
HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
P85A_HUMAN | [view interactions] | High throughput | no | yes |
PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BI2L1_HUMAN | [view interactions] | High throughput | no | yes |
DIP2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SEPT6_HUMAN | [view interactions] | High throughput | no | yes |
UNC5B_HUMAN | [view interactions] | High throughput | no | yes |
LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GAB1_HUMAN | [view interactions] | High throughput | no | yes |
EHBP1_HUMAN | [view interactions] | High throughput | no | yes |
IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSKI2_HUMAN | [view interactions] | High throughput | no | yes |
BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NOTC2_HUMAN | [view interactions] | High throughput | no | yes |
VAMP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDCA3_HUMAN | [view interactions] | High throughput | no | no |
NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
PDZ11_HUMAN | [view interactions] | High throughput | no | yes |
SNP29_HUMAN | [view interactions] | High throughput | no | yes |
ALK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPSB2_HUMAN | [view interactions] | High throughput | no | no |
RNF4_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
KIF23_HUMAN | [view interactions] | High throughput | no | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EFNB1_HUMAN | [view interactions] | High throughput | no | yes |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HECD1_HUMAN | [view interactions] | High throughput | no | yes |
LRIQ1_HUMAN | [view interactions] | High throughput | no | no |
NEU1_HUMAN | [view interactions] | High throughput | no | no |
B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
GPX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KITH_HUMAN | [view interactions] | High throughput | no | yes |
HMGA1_HUMAN | [view interactions] | High throughput | no | yes |
KPYR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACY1_HUMAN | [view interactions] | High throughput | no | no |
PA24C_HUMAN | [view interactions] | High throughput | no | yes |
PA2GE_HUMAN | [view interactions] | High throughput | no | no |
CSK_HUMAN | [view interactions] | High throughput | no | yes |
SRBP2_HUMAN | [view interactions] | High throughput | no | yes |
FBX7_HUMAN | [view interactions] | High throughput | no | yes |
ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KDM4A_HUMAN | [view interactions] | High throughput | no | yes |
ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
APH1B_HUMAN | [view interactions] | Computational | no | no |
EFNA3_HUMAN | [view interactions] | Computational | no | yes |
TACC3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EFNA1_HUMAN | [view interactions] | Computational | no | no |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EFNB3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
DYN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
BLK_HUMAN | [view interactions] | Computational | no | no |
NCK1_HUMAN | [view interactions] | Computational | no | yes |
RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
LYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MD2L1_HUMAN | [view interactions] | Computational | no | no |
M3K7_HUMAN | [view interactions] | Computational | no | yes |
RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RRAS_HUMAN | [view interactions] | Computational | no | yes |
L1CAM_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
UNC5C_HUMAN | [view interactions] | Computational | no | no |
CLH2_HUMAN | [view interactions] | Computational | no | no |
WASL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CCNA2_HUMAN | [view interactions] | Computational | no | no |
CENPE_HUMAN | [view interactions] | Computational | no | no |
FYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MMP9_HUMAN | [view interactions] | Computational | no | no |
PSN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CADH1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RGS3_HUMAN | [view interactions] | Computational | no | no |
CDK1_HUMAN | [view interactions] | Computational | no | no |
BOREA_HUMAN | [view interactions] | Computational | no | yes |
APH1A_HUMAN | [view interactions] | Computational | no | yes |
PEN2_HUMAN | [view interactions] | Computational | no | yes |
SH3G2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ASPM_HUMAN | [view interactions] | Computational | no | no |
SDC2_HUMAN | [view interactions] | Computational | no | yes |
EFNA2_HUMAN | [view interactions] | Computational | no | no |
KALRN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NICA_HUMAN | [view interactions] | Computational | no | yes |
PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EFNA4_HUMAN | [view interactions] | Computational | no | no |
NGEF_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FGR_HUMAN | [view interactions] | Computational | no | no |
PAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PSN2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PLK1_HUMAN | [view interactions] | Computational | no | yes |
KIF11_HUMAN | [view interactions] | Computational | no | yes |
CDC20_HUMAN | [view interactions] | Computational | no | no |
MMP2_HUMAN | [view interactions] | Computational | no | no |
LCK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ML12A_HUMAN | [view interactions] | Computational | no | no |