MYCB2_HUMAN
Evidence for PS localization
Functions
Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (PubMed). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (PubMed). Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3 (PubMed, PubMed). Plays a key role in neural development, probably by mediating ubiquitination of threonine residues on target proteins (Probable). Involved in different processes such as regulation of neurite outgrowth, synaptic growth, synaptogenesis and axon degeneration . Required for the formation of major central nervous system axon tracts . Required for proper axon growth by regulating axon navigation and axon branching: acts by regulating the subcellular location and stability of MAP3K12/DLK . Required for proper localization of retinogeniculate projections but not for eye-specific segregation . Regulates axon guidance in the olfactory system . Involved in Wallerian axon degeneration, an evolutionarily conserved process that drives the loss of damaged axons: acts by promoting destabilization of NMNAT2, probably via ubiquitination of NMNAT2 . Catalyzes ubiquitination of threonine and/or serine residues on NMNAT2, consequences of threonine and/or serine ubiquitination are however unknown (PubMed). Regulates the internalization of TRPV1 in peripheral sensory neurons . Mediates ubiquitination and subsequent proteasomal degradation of TSC2/tuberin (PubMed, PubMed). Independently of the E3 ubiquitin-protein ligase activity, also acts as a guanosine exchange factor (GEF) for RAN in neurons of dorsal root ganglia (PubMed). May function as a facilitator or regulator of transcriptional activation by MYC (PubMed). Acts in concert with HUWE1 to regulate the circadian clock gene expression by promoting the lithium-induced ubiquination and degradation of NR1D1 (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MYCB2_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 26.8293 | 4 | no |
| GO:0046872 | metal ion binding | 26.0163 | 4 | yes |
| GO:0003779 | actin binding | 22.7642 | 4 | no |
| GO:0045296 | cadherin binding | 21.9512 | 4 | no |
| GO:0019900 | kinase binding | 21.1382 | 4 | no |
| GO:0030695 | GTPase regulator activity | 8.1301 | 4 | yes |
| GO:0051020 | GTPase binding | 7.3171 | 4 | yes |
| GO:0008270 | zinc ion binding | 6.5041 | 6 | yes |
| GO:0031267 | small GTPase binding | 6.5041 | 5 | yes |
| GO:0046914 | transition metal ion binding | 6.5041 | 5 | yes |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 4.0650 | 5 | yes |
| GO:0004842 | ubiquitin-protein transferase activity | 1.6260 | 4 | yes |
| GO:0061630 | ubiquitin protein ligase activity | 1.6260 | 5 | yes |
| GO:0061659 | ubiquitin-like protein ligase activity | 1.6260 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MYCB2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.1626 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 52.8455 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 48.7805 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 47.9675 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 47.9675 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 47.1545 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.3415 | 4 | yes |
| GO:0006996 | organelle organization | 43.9024 | 4 | no |
| GO:0010646 | regulation of cell communication | 38.2114 | 4 | no |
| GO:0022607 | cellular component assembly | 37.3984 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 37.3984 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.5854 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 34.9593 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 33.3333 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.3333 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 30.0813 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.0813 | 5 | yes |
| GO:0008104 | protein localization | 30.0813 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 29.2683 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 29.2683 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 29.2683 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 28.4553 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 28.4553 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.6423 | 5 | no |
| GO:0031399 | regulation of protein modification process | 26.8293 | 6 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 26.8293 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 26.8293 | 5 | no |
| GO:0036211 | protein modification process | 26.0163 | 4 | yes |
| GO:0043412 | macromolecule modification | 26.0163 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 26.0163 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.0163 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 25.2033 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.2033 | 5 | no |
| GO:0071702 | organic substance transport | 25.2033 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.3902 | 5 | no |
| GO:0071705 | nitrogen compound transport | 24.3902 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.5772 | 6 | yes |
| GO:0010941 | regulation of cell death | 23.5772 | 4 | no |
| GO:0051049 | regulation of transport | 22.7642 | 4 | no |
| GO:0007010 | cytoskeleton organization | 22.7642 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 21.9512 | 6 | yes |
| GO:0042981 | regulation of apoptotic process | 21.9512 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 21.9512 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.1382 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 21.1382 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 21.1382 | 4 | no |
| GO:0015031 | protein transport | 20.3252 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 20.3252 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 20.3252 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 19.5122 | 6 | yes |
| GO:0060341 | regulation of cellular localization | 19.5122 | 4 | yes |
| GO:0030030 | cell projection organization | 19.5122 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 18.6992 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 18.6992 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 17.0732 | 7 | yes |
| GO:0032880 | regulation of protein localization | 17.0732 | 5 | yes |
| GO:0009894 | regulation of catabolic process | 17.0732 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 15.4472 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 10.5691 | 7 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 8.9431 | 5 | yes |
| GO:0032101 | regulation of response to external stimulus | 8.1301 | 4 | yes |
| GO:0032990 | cell part morphogenesis | 8.1301 | 4 | yes |
| GO:0048812 | neuron projection morphogenesis | 8.1301 | 7 | yes |
| GO:0048858 | cell projection morphogenesis | 8.1301 | 5 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 8.1301 | 6 | yes |
| GO:0042176 | regulation of protein catabolic process | 7.3171 | 5 | yes |
| GO:0031175 | neuron projection development | 6.5041 | 6 | yes |
| GO:0032446 | protein modification by small protein conjugation | 6.5041 | 6 | yes |
| GO:0009895 | negative regulation of catabolic process | 6.5041 | 5 | yes |
| GO:0016567 | protein ubiquitination | 5.6911 | 7 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 4.8780 | 7 | yes |
| GO:0007409 | axonogenesis | 4.8780 | 8 | yes |
| GO:0031396 | regulation of protein ubiquitination | 4.0650 | 8 | yes |
| GO:0050905 | neuromuscular process | 4.0650 | 4 | yes |
| GO:1903322 | positive regulation of protein modification by small protein conjugation or removal | 4.0650 | 8 | yes |
| GO:0021955 | central nervous system neuron axonogenesis | 4.0650 | 9 | yes |
| GO:0021952 | central nervous system projection neuron axonogenesis | 3.2520 | 10 | yes |
| GO:0031398 | positive regulation of protein ubiquitination | 2.4390 | 9 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 2.4390 | 6 | yes |
| GO:0050920 | regulation of chemotaxis | 2.4390 | 4 | yes |
| GO:0097485 | neuron projection guidance | 2.4390 | 7 | yes |
| GO:0007411 | axon guidance | 2.4390 | 8 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in MYCB2_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 4.0650 | 3 | no |
| DOID:114 | heart disease | 2.4390 | 3 | no |
| DOID:1289 | neurodegenerative disease | 2.4390 | 4 | no |
| DOID:0050700 | cardiomyopathy | 1.6260 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.6260 | 5 | no |
| DOID:2843 | long QT syndrome | 1.6260 | 6 | no |
| DOID:231 | motor neuron disease | 1.6260 | 5 | no |
| DOID:332 | amyotrophic lateral sclerosis | 1.6260 | 6 | no |
| DOID:936 | brain disease | 1.6260 | 4 | no |
| DOID:0050453 | lissencephaly | 1.6260 | 3 | no |
| DOID:0050686 | organ system cancer | 1.6260 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ROBO2_HUMAN | [view interactions] | Low throughput | no | yes |
| RAN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UB2D3_HUMAN | [view interactions] | Low throughput | no | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| FBSP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HEY1_HUMAN | [view interactions] | Low throughput | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| S12A5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAE1L_HUMAN | [view interactions] | Low throughput | no | no |
| SKP1_HUMAN | [view interactions] | Low throughput | no | yes |
| NMNA2_HUMAN | [view interactions] | Low throughput | no | no |
| NR1D1_HUMAN | [view interactions] | Low throughput | no | yes |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| PLA1A_HUMAN | [view interactions] | High throughput | no | no |
| H2A1C_HUMAN | [view interactions] | High throughput | no | yes |
| IBP4_HUMAN | [view interactions] | High throughput | no | no |
| H2A1H_HUMAN | [view interactions] | High throughput | no | yes |
| LPD6B_HUMAN | [view interactions] | High throughput | no | no |
| H2A2C_HUMAN | [view interactions] | High throughput | no | yes |
| PGLT1_HUMAN | [view interactions] | High throughput | no | no |
| EPMIP_HUMAN | [view interactions] | High throughput | no | no |
| HIPL1_HUMAN | [view interactions] | High throughput | no | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OIT3_HUMAN | [view interactions] | High throughput | no | no |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRN4L_HUMAN | [view interactions] | High throughput | no | yes |
| CC177_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CKAP2_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRR36_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| ARHGB_HUMAN | [view interactions] | High throughput | no | yes |
| UB2D2_HUMAN | [view interactions] | High throughput | no | yes |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| DLG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KDM3A_HUMAN | [view interactions] | High throughput | no | no |
| WIPI4_HUMAN | [view interactions] | High throughput | no | no |
| TRNK1_HUMAN | [view interactions] | High throughput | no | yes |
| UNC79_HUMAN | [view interactions] | High throughput | no | no |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| SYT3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CC14A_HUMAN | [view interactions] | High throughput | no | yes |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| PKN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET15_HUMAN | [view interactions] | High throughput | no | no |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB7_HUMAN | [view interactions] | High throughput | no | no |
| IQEC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZSC18_HUMAN | [view interactions] | High throughput | no | yes |
| ZN618_HUMAN | [view interactions] | High throughput | no | no |
| WDR18_HUMAN | [view interactions] | High throughput | no | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UACA_HUMAN | [view interactions] | High throughput | no | yes |
| TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TR150_HUMAN | [view interactions] | High throughput | no | yes |
| TEX10_HUMAN | [view interactions] | High throughput | no | no |
| TBCD5_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBP56_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| SSH2_HUMAN | [view interactions] | High throughput | no | no |
| SSH1_HUMAN | [view interactions] | High throughput | no | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMRC1_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L3_HUMAN | [view interactions] | High throughput | no | yes |
| SIPA1_HUMAN | [view interactions] | High throughput | no | yes |
| SF3B1_HUMAN | [view interactions] | High throughput | no | yes |
| SENP3_HUMAN | [view interactions] | High throughput | no | yes |
| SC31A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2C_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PELP1_HUMAN | [view interactions] | High throughput | no | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOL9_HUMAN | [view interactions] | High throughput | no | no |
| NFAC3_HUMAN | [view interactions] | High throughput | no | no |
| NEST_HUMAN | [view interactions] | High throughput | no | no |
| MYEF2_HUMAN | [view interactions] | High throughput | no | no |
| MBB1A_HUMAN | [view interactions] | High throughput | no | yes |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDN1_HUMAN | [view interactions] | High throughput | no | no |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRF1_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH2_HUMAN | [view interactions] | High throughput | no | no |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI21B_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4A1_HUMAN | [view interactions] | High throughput | no | no |
| EFHD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCLK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IBP6_HUMAN | [view interactions] | High throughput | no | yes |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHL3_HUMAN | [view interactions] | High throughput | no | no |
| DR4L2_HUMAN | [view interactions] | High throughput | no | no |
| CUED2_HUMAN | [view interactions] | High throughput | no | no |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| PXL2A_HUMAN | [view interactions] | High throughput | no | yes |
| ASB8_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| AATF_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRY3_HUMAN | [view interactions] | High throughput | no | yes |
| TBCD9_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| SPB6_HUMAN | [view interactions] | High throughput | no | yes |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGPD8_HUMAN | [view interactions] | High throughput | no | no |
| PUF60_HUMAN | [view interactions] | High throughput | no | yes |
| PI4KB_HUMAN | [view interactions] | High throughput | no | yes |
| PABP2_HUMAN | [view interactions] | High throughput | no | yes |
| OAZ1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LS14A_HUMAN | [view interactions] | High throughput | no | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBR1_HUMAN | [view interactions] | High throughput | no | yes |
| TBC9B_HUMAN | [view interactions] | High throughput | no | yes |
| SPRL1_HUMAN | [view interactions] | High throughput | no | no |
| AT132_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX2_HUMAN | [view interactions] | High throughput | no | no |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
| CPNE1_HUMAN | [view interactions] | High throughput | no | no |
| CPNE2_HUMAN | [view interactions] | High throughput | no | yes |
| CPNE4_HUMAN | [view interactions] | High throughput | no | no |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| CBX4_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| CD158_HUMAN | [view interactions] | High throughput | no | no |
| TDGF1_HUMAN | [view interactions] | High throughput | no | no |
| SESN3_HUMAN | [view interactions] | High throughput | no | no |
| DEFI6_HUMAN | [view interactions] | High throughput | no | no |
| SKAP1_HUMAN | [view interactions] | High throughput | no | no |
| CLC11_HUMAN | [view interactions] | High throughput | no | no |
| CASQ2_HUMAN | [view interactions] | High throughput | no | no |
| LIRA3_HUMAN | [view interactions] | High throughput | no | no |
| AL1L2_HUMAN | [view interactions] | High throughput | no | yes |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| STAT2_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CETN1_HUMAN | [view interactions] | High throughput | no | no |
| TXNIP_HUMAN | [view interactions] | High throughput | no | no |
| CAD19_HUMAN | [view interactions] | High throughput | no | no |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| DRC2_HUMAN | [view interactions] | High throughput | no | no |
| RAE1_HUMAN | [view interactions] | High throughput | no | yes |
| GCYB1_HUMAN | [view interactions] | High throughput | no | yes |
| WDR48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDF10_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACP7_HUMAN | [view interactions] | High throughput | no | no |
| HDA11_HUMAN | [view interactions] | High throughput | no | no |
| MYLIP_HUMAN | [view interactions] | High throughput | no | no |
| PGBD1_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| PDGFB_HUMAN | [view interactions] | High throughput | no | yes |
| SKA1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCDA3_HUMAN | [view interactions] | High throughput | no | no |
| SPRE2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| LNX1_HUMAN | [view interactions] | High throughput | no | yes |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLAI2_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| LG3BP_HUMAN | [view interactions] | High throughput | no | no |
| CGAS_HUMAN | [view interactions] | High throughput | no | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| VP26B_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| MEX3C_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| APBB1_HUMAN | [view interactions] | High throughput | no | yes |
| CSTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRC2_HUMAN | [view interactions] | High throughput | no | no |
| TESK1_HUMAN | [view interactions] | High throughput | no | no |
| NUP42_HUMAN | [view interactions] | High throughput | no | no |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIGN_HUMAN | [view interactions] | High throughput | no | yes |
| BAK_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| ICOS_HUMAN | [view interactions] | High throughput | no | no |
| SPXN2_HUMAN | [view interactions] | High throughput | no | no |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGFL3_HUMAN | [view interactions] | High throughput | no | no |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFPI2_HUMAN | [view interactions] | High throughput | no | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMP13_HUMAN | [view interactions] | High throughput | no | no |
| SMRC2_HUMAN | [view interactions] | High throughput | no | yes |
| RAD51_HUMAN | [view interactions] | High throughput | no | yes |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCDB6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCD10_HUMAN | [view interactions] | High throughput | no | yes |
| PDE1B_HUMAN | [view interactions] | High throughput | no | yes |
| TLR10_HUMAN | [view interactions] | High throughput | no | no |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EEA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP10_HUMAN | [view interactions] | High throughput | no | yes |
| FAXC_HUMAN | [view interactions] | High throughput | no | no |
| TPR_HUMAN | [view interactions] | High throughput | no | yes |
| RBPS2_HUMAN | [view interactions] | High throughput | no | no |
| SVIL_HUMAN | [view interactions] | High throughput | no | yes |
| ABCA2_HUMAN | [view interactions] | High throughput | no | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSRN1_HUMAN | [view interactions] | High throughput | no | no |
| PAG15_HUMAN | [view interactions] | High throughput | no | yes |
| ALPK2_HUMAN | [view interactions] | High throughput | no | no |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| INSL6_HUMAN | [view interactions] | High throughput | no | no |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1QB_HUMAN | [view interactions] | High throughput | no | no |
| SHOT1_HUMAN | [view interactions] | High throughput | no | no |
| IL25_HUMAN | [view interactions] | High throughput | no | no |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| GGH_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2A_HUMAN | [view interactions] | High throughput | no | yes |
| NGRN_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| NMB_HUMAN | [view interactions] | High throughput | no | no |
| H2A1D_HUMAN | [view interactions] | High throughput | no | yes |
| WNT5A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H2A1A_HUMAN | [view interactions] | High throughput | no | yes |
| FXRD2_HUMAN | [view interactions] | High throughput | no | yes |
| H2AJ_HUMAN | [view interactions] | High throughput | no | yes |
| ICAM4_HUMAN | [view interactions] | High throughput | no | no |
| H2A3_HUMAN | [view interactions] | High throughput | no | yes |
| ADAM7_HUMAN | [view interactions] | High throughput | no | no |
| H2A2B_HUMAN | [view interactions] | High throughput | no | yes |
| INHBE_HUMAN | [view interactions] | High throughput | no | no |
| H2A1J_HUMAN | [view interactions] | High throughput | no | yes |
| NDP_HUMAN | [view interactions] | High throughput | no | no |
| M3K13_HUMAN | [view interactions] | Computational | no | yes |
| UBB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| M3K12_HUMAN | [view entry] [view interactions] | Computational | yes | yes |