MYCB2_HUMAN
Evidence for PS localization
Functions
Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (PubMed). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (PubMed). Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3 (PubMed, PubMed). Plays a key role in neural development, probably by mediating ubiquitination of threonine residues on target proteins (Probable). Involved in different processes such as regulation of neurite outgrowth, synaptic growth, synaptogenesis and axon degeneration . Required for the formation of major central nervous system axon tracts . Required for proper axon growth by regulating axon navigation and axon branching: acts by regulating the subcellular location and stability of MAP3K12/DLK . Required for proper localization of retinogeniculate projections but not for eye-specific segregation . Regulates axon guidance in the olfactory system . Involved in Wallerian axon degeneration, an evolutionarily conserved process that drives the loss of damaged axons: acts by promoting destabilization of NMNAT2, probably via ubiquitination of NMNAT2 . Catalyzes ubiquitination of threonine and/or serine residues on NMNAT2, consequences of threonine and/or serine ubiquitination are however unknown (PubMed). Regulates the internalization of TRPV1 in peripheral sensory neurons . Mediates ubiquitination and subsequent proteasomal degradation of TSC2/tuberin (PubMed, PubMed). Independently of the E3 ubiquitin-protein ligase activity, also acts as a guanosine exchange factor (GEF) for RAN in neurons of dorsal root ganglia (PubMed). May function as a facilitator or regulator of transcriptional activation by MYC (PubMed). Acts in concert with HUWE1 to regulate the circadian clock gene expression by promoting the lithium-induced ubiquination and degradation of NR1D1 (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MYCB2_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 26.2774 | 4 | yes |
| GO:0046872 | metal ion binding | 26.2774 | 5 | yes |
| GO:0003723 | RNA binding | 24.8175 | 4 | no |
| GO:0003779 | actin binding | 21.1679 | 4 | no |
| GO:0030695 | GTPase regulator activity | 9.4891 | 4 | yes |
| GO:0051020 | GTPase binding | 8.7591 | 4 | yes |
| GO:0031267 | small GTPase binding | 7.2993 | 5 | yes |
| GO:0008270 | zinc ion binding | 5.8394 | 7 | yes |
| GO:0046914 | transition metal ion binding | 5.8394 | 6 | yes |
| GO:0016755 | aminoacyltransferase activity | 4.3796 | 4 | yes |
| GO:0004842 | ubiquitin-protein transferase activity | 3.6496 | 4 | yes |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 3.6496 | 5 | yes |
| GO:0061630 | ubiquitin protein ligase activity | 2.9197 | 5 | yes |
| GO:0061659 | ubiquitin-like protein ligase activity | 2.9197 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MYCB2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 58.3942 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 51.8248 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 51.0949 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 47.4453 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 46.7153 | 4 | yes |
| GO:0006996 | organelle organization | 45.2555 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 44.5255 | 4 | yes |
| GO:0010646 | regulation of cell communication | 41.6058 | 4 | no |
| GO:0022607 | cellular component assembly | 40.8759 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 38.6861 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 37.9562 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 37.2263 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 36.4964 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.0365 | 5 | yes |
| GO:0010468 | regulation of gene expression | 34.3066 | 6 | yes |
| GO:0009966 | regulation of signal transduction | 34.3066 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 32.1168 | 5 | yes |
| GO:0008104 | protein localization | 31.3869 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 29.9270 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 29.1971 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 28.4672 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 27.7372 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.2774 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 26.2774 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 25.5474 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.8175 | 5 | no |
| GO:0031399 | regulation of protein modification process | 23.3577 | 6 | yes |
| GO:0007010 | cytoskeleton organization | 23.3577 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.3577 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.6277 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.6277 | 6 | no |
| GO:0036211 | protein modification process | 21.8978 | 4 | yes |
| GO:0043412 | macromolecule modification | 21.8978 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 21.8978 | 4 | no |
| GO:0051049 | regulation of transport | 21.8978 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.1679 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 21.1679 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 21.1679 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 21.1679 | 5 | no |
| GO:0043933 | protein-containing complex organization | 21.1679 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 20.4380 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 20.4380 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 20.4380 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.4380 | 5 | no |
| GO:0071702 | organic substance transport | 20.4380 | 4 | no |
| GO:0071705 | nitrogen compound transport | 20.4380 | 4 | no |
| GO:0030030 | cell projection organization | 19.7080 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 19.7080 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 18.9781 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 18.9781 | 6 | yes |
| GO:0009894 | regulation of catabolic process | 18.2482 | 4 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 18.2482 | 6 | yes |
| GO:0032880 | regulation of protein localization | 17.5182 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 16.7883 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 16.0584 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 13.8686 | 7 | yes |
| GO:0010975 | regulation of neuron projection development | 11.6788 | 7 | yes |
| GO:0032101 | regulation of response to external stimulus | 10.9489 | 4 | yes |
| GO:0050807 | regulation of synapse organization | 10.9489 | 5 | yes |
| GO:0043687 | post-translational protein modification | 10.2190 | 5 | yes |
| GO:1901888 | regulation of cell junction assembly | 8.7591 | 5 | yes |
| GO:0031175 | neuron projection development | 8.0292 | 6 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 8.0292 | 6 | yes |
| GO:0032446 | protein modification by small protein conjugation | 6.5693 | 7 | yes |
| GO:0042176 | regulation of protein catabolic process | 6.5693 | 5 | yes |
| GO:0048812 | neuron projection morphogenesis | 6.5693 | 5 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 6.5693 | 4 | yes |
| GO:0016567 | protein ubiquitination | 5.8394 | 8 | yes |
| GO:0048638 | regulation of developmental growth | 5.8394 | 4 | yes |
| GO:0007409 | axonogenesis | 5.1095 | 6 | yes |
| GO:0009895 | negative regulation of catabolic process | 5.1095 | 5 | yes |
| GO:1901873 | regulation of post-translational protein modification | 5.1095 | 7 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 5.1095 | 8 | yes |
| GO:0031396 | regulation of protein ubiquitination | 4.3796 | 9 | yes |
| GO:0051963 | regulation of synapse assembly | 4.3796 | 6 | yes |
| GO:0007411 | axon guidance | 3.6496 | 8 | yes |
| GO:0050905 | neuromuscular process | 3.6496 | 4 | yes |
| GO:0097485 | neuron projection guidance | 3.6496 | 7 | yes |
| GO:1901875 | positive regulation of post-translational protein modification | 3.6496 | 8 | yes |
| GO:1903322 | positive regulation of protein modification by small protein conjugation or removal | 3.6496 | 9 | yes |
| GO:0000209 | protein polyubiquitination | 2.9197 | 9 | yes |
| GO:0021952 | central nervous system projection neuron axonogenesis | 2.9197 | 8 | yes |
| GO:0021955 | central nervous system neuron axonogenesis | 2.9197 | 7 | yes |
| GO:0031398 | positive regulation of protein ubiquitination | 2.9197 | 10 | yes |
| GO:0050920 | regulation of chemotaxis | 2.9197 | 4 | yes |
| GO:0070936 | protein K48-linked ubiquitination | 2.9197 | 10 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 2.1898 | 6 | yes |
| GO:1904396 | regulation of neuromuscular junction development | 1.4599 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| S12A5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HEY1_HUMAN | [view interactions] | Low throughput | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAE1L_HUMAN | [view interactions] | Low throughput | no | no |
| SKP1_HUMAN | [view interactions] | Low throughput | no | yes |
| NR1D1_HUMAN | [view interactions] | Low throughput | no | yes |
| NMNA2_HUMAN | [view interactions] | Low throughput | no | no |
| STK3_HUMAN | [view interactions] | Low throughput | no | yes |
| KIF2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RGS12_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ROBO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UB2D3_HUMAN | [view interactions] | Low throughput | no | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| FBSP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX2_HUMAN | [view interactions] | High throughput | no | no |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LCOR_HUMAN | [view interactions] | High throughput | no | yes |
| HUNK_HUMAN | [view interactions] | High throughput | no | yes |
| DSCR9_HUMAN | [view interactions] | High throughput | no | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| RSPH1_HUMAN | [view interactions] | High throughput | no | no |
| BTG3_HUMAN | [view interactions] | High throughput | no | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
| CPNE1_HUMAN | [view interactions] | High throughput | no | no |
| CPNE2_HUMAN | [view interactions] | High throughput | no | yes |
| CPNE4_HUMAN | [view interactions] | High throughput | no | no |
| SPAG6_HUMAN | [view interactions] | High throughput | no | no |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| CBX4_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| CD158_HUMAN | [view interactions] | High throughput | no | no |
| TDGF1_HUMAN | [view interactions] | High throughput | no | no |
| SESN3_HUMAN | [view interactions] | High throughput | no | no |
| DEFI6_HUMAN | [view interactions] | High throughput | no | no |
| SKAP1_HUMAN | [view interactions] | High throughput | no | no |
| CLC11_HUMAN | [view interactions] | High throughput | no | no |
| CASQ2_HUMAN | [view interactions] | High throughput | no | no |
| LIRA3_HUMAN | [view interactions] | High throughput | no | no |
| AL1L2_HUMAN | [view interactions] | High throughput | no | yes |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| RAE1_HUMAN | [view interactions] | High throughput | no | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| WDR48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| HDA11_HUMAN | [view interactions] | High throughput | no | no |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| STAT2_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SKA1_HUMAN | [view interactions] | High throughput | no | yes |
| CETN1_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXNIP_HUMAN | [view interactions] | High throughput | no | no |
| SPRE2_HUMAN | [view interactions] | High throughput | no | yes |
| CAD19_HUMAN | [view interactions] | High throughput | no | no |
| DRC2_HUMAN | [view interactions] | High throughput | no | no |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| GCYB1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDF10_HUMAN | [view interactions] | High throughput | no | yes |
| SLAI2_HUMAN | [view interactions] | High throughput | no | no |
| ACP7_HUMAN | [view interactions] | High throughput | no | no |
| LG3BP_HUMAN | [view interactions] | High throughput | no | no |
| MYLIP_HUMAN | [view interactions] | High throughput | no | no |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| PGBD1_HUMAN | [view interactions] | High throughput | no | no |
| VP26B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDGFB_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| PCDA3_HUMAN | [view interactions] | High throughput | no | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEX3C_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| APBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| TESK1_HUMAN | [view interactions] | High throughput | no | no |
| CGAS_HUMAN | [view interactions] | High throughput | no | yes |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAK_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ICOS_HUMAN | [view interactions] | High throughput | no | no |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRC2_HUMAN | [view interactions] | High throughput | no | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP42_HUMAN | [view interactions] | High throughput | no | no |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| PIGN_HUMAN | [view interactions] | High throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPXN2_HUMAN | [view interactions] | High throughput | no | no |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGFL3_HUMAN | [view interactions] | High throughput | no | no |
| DCLK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFPI2_HUMAN | [view interactions] | High throughput | no | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMP13_HUMAN | [view interactions] | High throughput | no | no |
| DCX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD51_HUMAN | [view interactions] | High throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCDB6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLR10_HUMAN | [view interactions] | High throughput | no | no |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EEA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAXC_HUMAN | [view interactions] | High throughput | no | no |
| EFHD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBPS2_HUMAN | [view interactions] | High throughput | no | no |
| IF4A1_HUMAN | [view interactions] | High throughput | no | no |
| ABCA2_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSRN1_HUMAN | [view interactions] | High throughput | no | no |
| EPMIP_HUMAN | [view interactions] | High throughput | no | no |
| ALPK2_HUMAN | [view interactions] | High throughput | no | no |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| INSL6_HUMAN | [view interactions] | High throughput | no | no |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1QB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| IL25_HUMAN | [view interactions] | High throughput | no | no |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| GGH_HUMAN | [view interactions] | High throughput | no | yes |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NGRN_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| NMB_HUMAN | [view interactions] | High throughput | no | no |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| WNT5A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H2A2A_HUMAN | [view interactions] | High throughput | no | yes |
| FXRD2_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| ICAM4_HUMAN | [view interactions] | High throughput | no | no |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| ADAM7_HUMAN | [view interactions] | High throughput | no | no |
| H2A1D_HUMAN | [view interactions] | High throughput | no | yes |
| INHBE_HUMAN | [view interactions] | High throughput | no | no |
| H2AJ_HUMAN | [view interactions] | High throughput | no | yes |
| NDP_HUMAN | [view interactions] | High throughput | no | no |
| H2A1A_HUMAN | [view interactions] | High throughput | no | yes |
| PLA1A_HUMAN | [view interactions] | High throughput | no | no |
| H2A2B_HUMAN | [view interactions] | High throughput | no | yes |
| IBP4_HUMAN | [view interactions] | High throughput | no | no |
| H2A3_HUMAN | [view interactions] | High throughput | no | yes |
| LPD6B_HUMAN | [view interactions] | High throughput | no | no |
| H2A1J_HUMAN | [view interactions] | High throughput | no | yes |
| PGLT1_HUMAN | [view interactions] | High throughput | no | no |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| HIPL1_HUMAN | [view interactions] | High throughput | no | no |
| H2A1C_HUMAN | [view interactions] | High throughput | no | yes |
| OIT3_HUMAN | [view interactions] | High throughput | no | no |
| H2A2C_HUMAN | [view interactions] | High throughput | no | yes |
| LRN4L_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1H_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP2_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHOT1_HUMAN | [view interactions] | High throughput | no | no |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KI21B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SERC5_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH2_HUMAN | [view interactions] | High throughput | no | no |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| LRRF1_HUMAN | [view interactions] | High throughput | no | yes |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO10_HUMAN | [view interactions] | High throughput | no | no |
| MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
| DPTOR_HUMAN | [view interactions] | High throughput | no | no |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| MBB1A_HUMAN | [view interactions] | High throughput | no | yes |
| MYEF2_HUMAN | [view interactions] | High throughput | no | no |
| NEST_HUMAN | [view interactions] | High throughput | no | no |
| NFAC3_HUMAN | [view interactions] | High throughput | no | no |
| NOL9_HUMAN | [view interactions] | High throughput | no | no |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2D2_HUMAN | [view interactions] | High throughput | no | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| PELP1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| PAG15_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KDM3A_HUMAN | [view interactions] | High throughput | no | no |
| NEB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRNK1_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CC14A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2C_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MET15_HUMAN | [view interactions] | High throughput | no | no |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJB7_HUMAN | [view interactions] | High throughput | no | no |
| SC31A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SENP3_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| SF3B1_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| SIPA1_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| SMRC1_HUMAN | [view interactions] | High throughput | no | yes |
| PF21A_HUMAN | [view interactions] | High throughput | no | yes |
| SMRC2_HUMAN | [view interactions] | High throughput | no | yes |
| RCOR1_HUMAN | [view interactions] | High throughput | no | yes |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIAO1_HUMAN | [view interactions] | High throughput | no | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBBP7_HUMAN | [view interactions] | High throughput | no | yes |
| SSH1_HUMAN | [view interactions] | High throughput | no | yes |
| COP1_HUMAN | [view interactions] | High throughput | no | no |
| SSH2_HUMAN | [view interactions] | High throughput | no | no |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| SVIL_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| WWTR1_HUMAN | [view interactions] | High throughput | no | yes |
| RBP56_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBCD5_HUMAN | [view interactions] | High throughput | no | yes |
| TEX10_HUMAN | [view interactions] | High throughput | no | no |
| TR150_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPR_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UACA_HUMAN | [view interactions] | High throughput | no | yes |
| UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP10_HUMAN | [view interactions] | High throughput | no | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR18_HUMAN | [view interactions] | High throughput | no | yes |
| ZN618_HUMAN | [view interactions] | High throughput | no | no |
| ZSC18_HUMAN | [view interactions] | High throughput | no | yes |
| AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQEC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UNC79_HUMAN | [view interactions] | High throughput | no | no |
| WIPI4_HUMAN | [view interactions] | High throughput | no | no |
| DLG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHGB_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRR36_HUMAN | [view interactions] | High throughput | no | no |
| BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| CCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| CC177_HUMAN | [view interactions] | High throughput | no | no |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIMS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHL3_HUMAN | [view interactions] | High throughput | no | no |
| DR4L2_HUMAN | [view interactions] | High throughput | no | no |
| CUED2_HUMAN | [view interactions] | High throughput | no | no |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| PXL2A_HUMAN | [view interactions] | High throughput | no | yes |
| ASB8_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| AATF_HUMAN | [view interactions] | High throughput | no | yes |
| IBP6_HUMAN | [view interactions] | High throughput | no | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LS14A_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OAZ1_HUMAN | [view interactions] | High throughput | no | yes |
| PABP2_HUMAN | [view interactions] | High throughput | no | yes |
| PI4KB_HUMAN | [view interactions] | High throughput | no | yes |
| PUF60_HUMAN | [view interactions] | High throughput | no | yes |
| RGPD8_HUMAN | [view interactions] | High throughput | no | no |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPB6_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| SPRL1_HUMAN | [view interactions] | High throughput | no | no |
| SPRY3_HUMAN | [view interactions] | High throughput | no | yes |
| TBCD9_HUMAN | [view interactions] | High throughput | no | yes |
| TBC9B_HUMAN | [view interactions] | High throughput | no | yes |
| TBR1_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT132_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB3_HUMAN | [view interactions] | High throughput | no | yes |