Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KCC2B_HUMAN

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Also regulates the migration of developing neurons (PubMed). Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in KCC2B_HUMAN
GO:0046872 metal ion binding 28.9720 4 no
GO:0017076 purine nucleotide binding 27.1028 4 yes
GO:0032555 purine ribonucleotide binding 27.1028 4 yes
GO:0019900 kinase binding 26.1682 4 no
GO:0035639 purine ribonucleoside triphosphate binding 25.2336 4 yes
GO:0019901 protein kinase binding 25.2336 5 no
GO:0030554 adenyl nucleotide binding 20.5607 5 yes
GO:0032559 adenyl ribonucleotide binding 20.5607 5 yes
GO:0005524 ATP binding 18.6916 5 yes
GO:0003779 actin binding 14.9533 4 yes
GO:0042803 protein homodimerization activity 14.9533 4 yes
GO:0016301 kinase activity 14.0187 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 14.0187 4 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 13.0841 4 yes
GO:0004674 protein serine/threonine kinase activity 11.2150 4 yes
GO:0106310 protein serine kinase activity 10.2804 4 yes
GO:0004683 calmodulin-dependent protein kinase activity 8.4112 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KCC2B_HUMAN
GO:0048522 positive regulation of cellular process 68.2243 4 yes
GO:0010646 regulation of cell communication 61.6822 4 yes
GO:0060255 regulation of macromolecule metabolic process 58.8785 4 no
GO:0080090 regulation of primary metabolic process 57.0093 4 no
GO:0051171 regulation of nitrogen compound metabolic process 56.0748 4 no
GO:0031323 regulation of cellular metabolic process 54.2056 4 no
GO:0048523 negative regulation of cellular process 50.4673 4 no
GO:0009966 regulation of signal transduction 49.5327 4 no
GO:0009893 positive regulation of metabolic process 45.7944 4 no
GO:0051049 regulation of transport 43.9252 4 yes
GO:0051246 regulation of protein metabolic process 43.9252 5 no
GO:0010604 positive regulation of macromolecule metabolic process 42.9907 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 42.0561 5 no
GO:0010468 regulation of gene expression 41.1215 5 no
GO:0031325 positive regulation of cellular metabolic process 40.1869 5 no
GO:0050804 modulation of chemical synaptic transmission 39.2523 5 yes
GO:0051128 regulation of cellular component organization 39.2523 4 yes
GO:0099177 regulation of trans-synaptic signaling 39.2523 4 yes
GO:0031399 regulation of protein modification process 37.3832 6 no
GO:0009889 regulation of biosynthetic process 34.5794 4 no
GO:0031326 regulation of cellular biosynthetic process 34.5794 5 no
GO:0019220 regulation of phosphate metabolic process 34.5794 6 no
GO:0051174 regulation of phosphorus metabolic process 34.5794 5 no
GO:0010556 regulation of macromolecule biosynthetic process 33.6449 5 no
GO:0010647 positive regulation of cell communication 33.6449 5 no
GO:0023056 positive regulation of signaling 33.6449 4 no
GO:0051247 positive regulation of protein metabolic process 32.7103 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 31.7757 5 no
GO:0042325 regulation of phosphorylation 31.7757 7 no
GO:0043269 regulation of ion transport 30.8411 5 yes
GO:0009892 negative regulation of metabolic process 29.9065 4 no
GO:0010605 negative regulation of macromolecule metabolic process 29.9065 5 no
GO:0001932 regulation of protein phosphorylation 29.9065 7 no
GO:0022607 cellular component assembly 29.9065 4 no
GO:0008104 protein localization 28.9720 4 no
GO:0048584 positive regulation of response to stimulus 28.9720 4 no
GO:1902531 regulation of intracellular signal transduction 28.9720 5 no
GO:0006996 organelle organization 28.9720 4 no
GO:0010941 regulation of cell death 28.9720 4 no
GO:0051050 positive regulation of transport 28.0374 4 no
GO:0031401 positive regulation of protein modification process 28.0374 7 no
GO:0036211 protein modification process 27.1028 4 yes
GO:0043412 macromolecule modification 27.1028 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 27.1028 5 no
GO:0051252 regulation of RNA metabolic process 27.1028 5 no
GO:0010243 response to organonitrogen compound 26.1682 4 no
GO:0010562 positive regulation of phosphorus metabolic process 26.1682 6 no
GO:0034762 regulation of transmembrane transport 26.1682 4 no
GO:0042327 positive regulation of phosphorylation 26.1682 8 no
GO:0043085 positive regulation of catalytic activity 26.1682 4 no
GO:0045937 positive regulation of phosphate metabolic process 26.1682 7 no
GO:0043067 regulation of programmed cell death 26.1682 5 no
GO:0031344 regulation of cell projection organization 25.2336 5 yes
GO:0071310 cellular response to organic substance 25.2336 4 no
GO:0001934 positive regulation of protein phosphorylation 25.2336 8 no
GO:0034765 regulation of ion transmembrane transport 25.2336 5 no
GO:0042981 regulation of apoptotic process 25.2336 6 no
GO:0044057 regulation of system process 24.2991 4 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 24.2991 6 yes
GO:0031324 negative regulation of cellular metabolic process 24.2991 5 no
GO:0060341 regulation of cellular localization 24.2991 4 no
GO:1903506 regulation of nucleic acid-templated transcription 24.2991 7 no
GO:2001141 regulation of RNA biosynthetic process 24.2991 6 no
GO:0045595 regulation of cell differentiation 23.3645 4 yes
GO:0051240 positive regulation of multicellular organismal process 23.3645 4 yes
GO:0006355 regulation of DNA-templated transcription 23.3645 6 no
GO:0071702 organic substance transport 23.3645 4 no
GO:0071705 nitrogen compound transport 23.3645 4 no
GO:0051338 regulation of transferase activity 23.3645 4 no
GO:1904062 regulation of cation transmembrane transport 23.3645 6 no
GO:0006796 phosphate-containing compound metabolic process 22.4299 4 yes
GO:0051094 positive regulation of developmental process 22.4299 4 yes
GO:0009891 positive regulation of biosynthetic process 22.4299 5 no
GO:0031328 positive regulation of cellular biosynthetic process 22.4299 6 no
GO:1901701 cellular response to oxygen-containing compound 22.4299 4 no
GO:0022898 regulation of transmembrane transporter activity 22.4299 4 no
GO:0043549 regulation of kinase activity 22.4299 5 no
GO:0009967 positive regulation of signal transduction 22.4299 5 no
GO:0051130 positive regulation of cellular component organization 21.4953 5 yes
GO:0010648 negative regulation of cell communication 21.4953 5 no
GO:0023057 negative regulation of signaling 21.4953 4 no
GO:0045859 regulation of protein kinase activity 21.4953 6 no
GO:0051248 negative regulation of protein metabolic process 21.4953 6 no
GO:0044087 regulation of cellular component biogenesis 21.4953 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 20.5607 6 no
GO:0032880 regulation of protein localization 20.5607 5 no
GO:0032412 regulation of ion transmembrane transporter activity 20.5607 5 no
GO:0051336 regulation of hydrolase activity 20.5607 4 no
GO:0010959 regulation of metal ion transport 19.6262 6 yes
GO:0022603 regulation of anatomical structure morphogenesis 15.8879 4 yes
GO:0045597 positive regulation of cell differentiation 15.8879 5 yes
GO:0051924 regulation of calcium ion transport 15.8879 7 yes
GO:2000026 regulation of multicellular organismal development 15.8879 4 yes
GO:0010975 regulation of neuron projection development 14.9533 7 yes
GO:0006468 protein phosphorylation 14.0187 5 yes
GO:0016310 phosphorylation 14.0187 5 yes
GO:0060284 regulation of cell development 14.0187 5 yes
GO:0030334 regulation of cell migration 13.0841 5 yes
GO:0031346 positive regulation of cell projection organization 13.0841 6 yes
GO:2000145 regulation of cell motility 13.0841 4 yes
GO:0048168 regulation of neuronal synaptic plasticity 12.1495 4 yes
GO:0050807 regulation of synapse organization 11.2150 5 yes
GO:0051960 regulation of nervous system development 11.2150 5 yes
GO:0090257 regulation of muscle system process 11.2150 5 yes
GO:0010720 positive regulation of cell development 10.2804 6 yes
GO:0046777 protein autophosphorylation 10.2804 6 yes
GO:0050767 regulation of neurogenesis 10.2804 6 yes
GO:0022604 regulation of cell morphogenesis 9.3458 5 yes
GO:0048169 regulation of long-term neuronal synaptic plasticity 9.3458 5 yes
GO:0051962 positive regulation of nervous system development 9.3458 5 yes
GO:0050769 positive regulation of neurogenesis 8.4112 6 yes
GO:0043502 regulation of muscle adaptation 6.5421 4 yes
GO:0099175 regulation of postsynapse organization 6.5421 6 yes
GO:0010976 positive regulation of neuron projection development 5.6075 7 yes
GO:0010769 regulation of cell morphogenesis involved in differentiation 4.6729 6 yes
GO:0050773 regulation of dendrite development 4.6729 4 yes
GO:0060998 regulation of dendritic spine development 4.6729 4 yes
GO:0060999 positive regulation of dendritic spine development 4.6729 5 yes
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 3.7383 7 yes
GO:0014733 regulation of skeletal muscle adaptation 3.7383 5 yes
GO:0048814 regulation of dendrite morphogenesis 3.7383 5 yes
GO:0061001 regulation of dendritic spine morphogenesis 3.7383 5 yes
GO:0090128 regulation of synapse maturation 3.7383 4 yes
GO:0051823 regulation of synapse structural plasticity 2.8037 6 yes
GO:0090129 positive regulation of synapse maturation 2.8037 5 yes
GO:2001222 regulation of neuron migration 2.8037 6 yes
GO:0050775 positive regulation of dendrite morphogenesis 1.8692 6 yes
GO:0061003 positive regulation of dendritic spine morphogenesis 1.8692 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in KCC2B_HUMAN
DOID:114 heart disease 6.5421 3 no
DOID:0050700 cardiomyopathy 5.6075 4 no
DOID:0060036 intrinsic cardiomyopathy 5.6075 5 no
DOID:331 central nervous system disease 4.6729 3 no
DOID:2843 long QT syndrome 2.8037 6 no
DOID:1289 neurodegenerative disease 2.8037 4 no
DOID:0050753 cerebellar ataxia 1.8692 6 no
DOID:0050950 autosomal recessive cerebellar ataxia 1.8692 7 no
DOID:0050951 hereditary ataxia 1.8692 5 no
DOID:0060038 specific developmental disorder 1.8692 3 no
DOID:1059 intellectual disability 1.8692 4 no
DOID:0060674 catecholaminergic polymorphic ventricular tachycardia 1.8692 5 no
DOID:10273 heart conduction disease 1.8692 4 no
DOID:936 brain disease 1.8692 4 no
DOID:0080000 muscular disease 1.8692 3 no
DOID:423 myopathy 1.8692 5 no
DOID:65 connective tissue disease 1.8692 3 no
DOID:66 muscle tissue disease 1.8692 4 no
DOID:9884 muscular dystrophy 1.8692 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ARC_HUMAN [view entry] [view interactions] Low throughput yes no
PRS8_HUMAN [view interactions] Low throughput no yes
KCC2A_HUMAN [view entry] [view interactions] Low throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] Low throughput yes no
NMDE2_HUMAN [view entry] [view interactions] Low throughput yes no
CALM2_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM3_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
FLII_HUMAN [view entry] [view interactions] Low throughput yes yes
SYGP1_HUMAN [view entry] [view interactions] Low throughput yes yes
KCC2B_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTB_HUMAN [view entry] [view interactions] Low throughput yes no
ACTN4_HUMAN [view entry] [view interactions] Low throughput yes yes
CDC20_HUMAN [view interactions] Low throughput no no
PTPRR_HUMAN [view interactions] Low throughput no yes
1433B_HUMAN [view entry] [view interactions] Low throughput yes yes
1433E_HUMAN [view entry] [view interactions] Low throughput yes yes
TBG1_HUMAN [view entry] [view interactions] Low throughput yes yes
MPDZ_HUMAN [view entry] [view interactions] Low throughput yes yes
GLUT4_HUMAN [view interactions] High throughput no no
KCC2D_HUMAN [view entry] [view interactions] High throughput yes yes
MECOM_HUMAN [view interactions] High throughput no yes
NMDZ1_HUMAN [view entry] [view interactions] High throughput yes yes
GRID2_HUMAN [view entry] [view interactions] High throughput yes no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
RD23B_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
FGR_HUMAN [view interactions] High throughput no no
PNMA2_HUMAN [view interactions] High throughput no yes
STRN4_HUMAN [view entry] [view interactions] High throughput yes yes
SLMAP_HUMAN [view entry] [view interactions] High throughput yes yes
ITPR3_HUMAN [view interactions] High throughput no yes
ITPR2_HUMAN [view interactions] High throughput no yes
KCC2G_HUMAN [view entry] [view interactions] High throughput yes yes
STRN3_HUMAN [view interactions] High throughput no yes
ITPI2_HUMAN [view interactions] High throughput no yes
PDE4A_HUMAN [view interactions] High throughput no no
STRN_HUMAN [view entry] [view interactions] High throughput yes yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
PKN3_HUMAN [view interactions] High throughput no yes
M3K2_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
NEUL1_HUMAN [view entry] [view interactions] High throughput yes yes
AAPK1_HUMAN [view interactions] High throughput no no
CNKR2_HUMAN [view entry] [view interactions] High throughput yes no
CYFP1_HUMAN [view entry] [view interactions] High throughput yes yes
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
MYOME_HUMAN [view interactions] High throughput no no
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP1_HUMAN [view entry] [view interactions] High throughput yes no
AGAP2_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
SMYD3_HUMAN [view interactions] High throughput no yes
BACH_HUMAN [view entry] [view interactions] High throughput yes yes
RFOX2_HUMAN [view interactions] High throughput no yes
KR10B_HUMAN [view interactions] High throughput no no
RAP2B_HUMAN [view interactions] High throughput no no
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
AP5B1_HUMAN [view interactions] High throughput no yes
KR195_HUMAN [view interactions] High throughput no no
KR197_HUMAN [view interactions] High throughput no no
SPRY7_HUMAN [view interactions] High throughput no yes
TTC5_HUMAN [view interactions] High throughput no yes
RBPMS_HUMAN [view interactions] High throughput no no
KPBB_HUMAN [view interactions] High throughput no no
POP5_HUMAN [view interactions] High throughput no no
MED18_HUMAN [view interactions] High throughput no yes
MO4L1_HUMAN [view interactions] High throughput no yes
MD2L2_HUMAN [view interactions] High throughput no yes
RM11_HUMAN [view interactions] High throughput no yes
FXR2_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
PCNA_HUMAN [view interactions] High throughput no no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
NINL_HUMAN [view interactions] High throughput no yes
TANK_HUMAN [view interactions] High throughput no yes
THB_HUMAN [view interactions] High throughput no no
RXRG_HUMAN [view interactions] High throughput no no
MVP_HUMAN [view entry] [view interactions] High throughput yes yes
SEM4G_HUMAN [view interactions] High throughput no yes
CCM2L_HUMAN [view interactions] High throughput no no
MGT5B_HUMAN [view interactions] High throughput no no
F1712_HUMAN [view interactions] High throughput no no
ZBT32_HUMAN [view interactions] High throughput no yes
PNKP_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
TNPO3_HUMAN [view interactions] High throughput no yes
ARSA_HUMAN [view interactions] High throughput no yes
CDC37_HUMAN [view interactions] High throughput no yes
TNPO2_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
MO4L2_HUMAN [view interactions] High throughput no yes
ZMYM5_HUMAN [view interactions] High throughput no yes
DUS1L_HUMAN [view interactions] High throughput no yes
KRT86_HUMAN [view interactions] High throughput no no
RPC3_HUMAN [view interactions] High throughput no yes
KRA62_HUMAN [view interactions] High throughput no no
KRA11_HUMAN [view interactions] High throughput no no
KR193_HUMAN [view interactions] High throughput no no
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
STB5L_HUMAN [view interactions] High throughput no no
ARMC1_HUMAN [view interactions] High throughput no yes
HAX1_HUMAN [view interactions] High throughput no no
NUFP1_HUMAN [view interactions] High throughput no yes
DGUOK_HUMAN [view interactions] High throughput no yes
KTU_HUMAN [view interactions] High throughput no yes
ASAH1_HUMAN [view interactions] High throughput no yes
LIPH_HUMAN [view interactions] High throughput no no
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
RBM42_HUMAN [view interactions] High throughput no yes
CF141_HUMAN [view interactions] High throughput no no
ZN843_HUMAN [view interactions] High throughput no yes
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
INADL_HUMAN [view interactions] High throughput no no
KALRN_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPL_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
CSN5_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
FZR1_HUMAN [view interactions] High throughput no no
DNAL4_HUMAN [view interactions] High throughput no yes
P121A_HUMAN [view interactions] High throughput no yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
E41LB_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
MCM5_HUMAN [view interactions] High throughput no no
TCPQM_HUMAN [view interactions] High throughput no no
RDH8_HUMAN [view interactions] High throughput no no
F163B_HUMAN [view interactions] High throughput no yes
EFMT2_HUMAN [view interactions] High throughput no yes
NAA11_HUMAN [view interactions] High throughput no no
VCIP1_HUMAN [view entry] [view interactions] High throughput yes no
HNRC2_HUMAN [view interactions] High throughput no no
MAGA9_HUMAN [view interactions] High throughput no no
SHSA6_HUMAN [view entry] [view interactions] High throughput yes no
MAP10_HUMAN [view interactions] High throughput no no
WDR5B_HUMAN [view interactions] High throughput no yes
CT096_HUMAN [view interactions] High throughput no yes
TRAT1_HUMAN [view interactions] High throughput no no
PIGH_HUMAN [view interactions] High throughput no yes
DUS4L_HUMAN [view interactions] High throughput no yes
F170A_HUMAN [view interactions] High throughput no no
ZN397_HUMAN [view interactions] High throughput no yes
NUP43_HUMAN [view interactions] High throughput no yes
ZN764_HUMAN [view interactions] High throughput no no
TPC2L_HUMAN [view interactions] High throughput no yes
AAKG2_HUMAN [view interactions] High throughput no yes
HSPB8_HUMAN [view entry] [view interactions] High throughput yes yes
PALD_HUMAN [view interactions] High throughput no yes
ZSCA1_HUMAN [view interactions] High throughput no yes
SYQ_HUMAN [view interactions] High throughput no yes
ELP3_HUMAN [view interactions] High throughput no no
TTLL1_HUMAN [view interactions] High throughput no yes
PADI4_HUMAN [view interactions] High throughput no no
ANGL7_HUMAN [view interactions] High throughput no no
MECP2_HUMAN [view interactions] High throughput no yes
CD22_HUMAN [view interactions] High throughput no no
ACY1_HUMAN [view interactions] High throughput no no
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
CREB1_HUMAN [view interactions] Computational no yes
AGGF1_HUMAN [view interactions] Computational no no
HSF1_HUMAN [view interactions] Computational no yes
NOS1_HUMAN [view entry] [view interactions] Computational yes yes
PPM1F_HUMAN [view interactions] Computational no yes
NMDE1_HUMAN [view entry] [view interactions] Computational yes yes
MPIP3_HUMAN [view interactions] Computational no yes
CK2N2_HUMAN [view interactions] Computational no yes
F1142_HUMAN [view interactions] Computational no yes
EP300_HUMAN [view interactions] Computational no yes
RAP1B_HUMAN [view entry] [view interactions] Computational yes no
PP1B_HUMAN [view entry] [view interactions] Computational yes yes
KKCC1_HUMAN [view entry] [view interactions] Computational yes yes
MEF2C_HUMAN [view interactions] Computational no yes
CCG2_HUMAN [view entry] [view interactions] Computational yes no
GRIA3_HUMAN [view entry] [view interactions] Computational yes yes
E41L1_HUMAN [view entry] [view interactions] Computational yes yes
ATRAP_HUMAN [view interactions] Computational no yes
MYO6_HUMAN [view entry] [view interactions] Computational yes no
AKAP5_HUMAN [view entry] [view interactions] Computational yes yes
GRIA1_HUMAN [view entry] [view interactions] Computational yes yes
JAK1_HUMAN [view interactions] Computational no yes
SRC_HUMAN [view entry] [view interactions] Computational yes no
CLCN6_HUMAN [view interactions] Computational no yes
ZCCHV_HUMAN [view interactions] Computational no yes
RASK_HUMAN [view entry] [view interactions] Computational yes no
CY24B_HUMAN [view interactions] Computational no no
F131B_HUMAN [view interactions] Computational no no
HDAC9_HUMAN [view interactions] Computational no yes
CCG4_HUMAN [view entry] [view interactions] Computational yes no
MARCS_HUMAN [view entry] [view interactions] Computational yes yes
ESRP1_HUMAN [view interactions] Computational no yes
SC6A3_HUMAN [view entry] [view interactions] Computational yes yes
PP2BB_HUMAN [view entry] [view interactions] Computational yes yes
PP2BC_HUMAN [view interactions] Computational no yes
MEF2D_HUMAN [view interactions] Computational no yes
HDAC5_HUMAN [view interactions] Computational no yes
TIF1A_HUMAN [view interactions] Computational no yes
LMNA_HUMAN [view entry] [view interactions] Computational yes yes
KDM7A_HUMAN [view interactions] Computational no yes
KKCC2_HUMAN [view entry] [view interactions] Computational yes yes
CCG3_HUMAN [view entry] [view interactions] Computational yes no
IFNG_HUMAN [view interactions] Computational no no
PLCG2_HUMAN [view interactions] Computational no yes
GRIA4_HUMAN [view entry] [view interactions] Computational yes no
FLNC_HUMAN [view entry] [view interactions] Computational yes no
GRIA2_HUMAN [view entry] [view interactions] Computational yes yes
AP3B1_HUMAN [view entry] [view interactions] Computational yes yes
CABIN_HUMAN [view interactions] Computational no yes
TRAK1_HUMAN [view interactions] Computational no yes
RAP1A_HUMAN [view entry] [view interactions] Computational yes no
B2L11_HUMAN [view interactions] Computational no yes
PLCG1_HUMAN [view entry] [view interactions] Computational yes yes
CAV1_HUMAN [view interactions] Computational no no
MP2K3_HUMAN [view entry] [view interactions] Computational yes yes
AKAP9_HUMAN [view entry] [view interactions] Computational yes yes
MARK3_HUMAN [view interactions] Computational no yes
MYLK_HUMAN [view interactions] Computational no no
NOS3_HUMAN [view interactions] Computational no no
FAK2_HUMAN [view entry] [view interactions] Computational yes yes
MPRIP_HUMAN [view entry] [view interactions] Computational yes yes
RIPK3_HUMAN [view interactions] Computational no no
INGR2_HUMAN [view interactions] Computational no yes
GRM5_HUMAN [view entry] [view interactions] Computational yes no
PP2BA_HUMAN [view entry] [view interactions] Computational yes yes
CCG8_HUMAN [view entry] [view interactions] Computational yes no
ADCY3_HUMAN [view interactions] Computational no yes
RASN_HUMAN [view entry] [view interactions] Computational yes no
KCC4_HUMAN [view entry] [view interactions] Computational yes yes
INGR1_HUMAN [view interactions] Computational no no
MEF2A_HUMAN [view interactions] Computational no yes
FBX43_HUMAN [view interactions] Computational no no
HDAC1_HUMAN [view interactions] Computational no no
QKI_HUMAN [view interactions] Computational no no
GRM1_HUMAN [view entry] [view interactions] Computational yes yes
PAPS1_HUMAN [view interactions] Computational no yes
ATG7_HUMAN [view interactions] Computational no yes
STMN1_HUMAN [view interactions] Computational no yes
M3K5_HUMAN [view interactions] Computational no yes
RAC1_HUMAN [view entry] [view interactions] Computational yes no
PP1A_HUMAN [view entry] [view interactions] Computational yes yes
KSR1_HUMAN [view interactions] Computational no yes
MP2K6_HUMAN [view interactions] Computational no yes
FLNA_HUMAN [view entry] [view interactions] Computational yes no
SND1_HUMAN [view entry] [view interactions] Computational yes yes
MDM2_HUMAN [view interactions] Computational no yes
FLNB_HUMAN [view interactions] Computational no no
PP1G_HUMAN [view entry] [view interactions] Computational yes yes
HDAC2_HUMAN [view interactions] Computational no yes
K1549_HUMAN [view entry] [view interactions] Computational yes yes
JAK2_HUMAN [view entry] [view interactions] Computational yes yes
RASH_HUMAN [view entry] [view interactions] Computational yes no
TRPV1_HUMAN [view entry] [view interactions] Computational yes no
PK3C3_HUMAN [view interactions] Computational no yes
STAT1_HUMAN [view entry] [view interactions] Computational yes no
RYR2_HUMAN [view entry] [view interactions] Computational yes yes
CBP_HUMAN [view interactions] Computational no yes