KCC2B_HUMAN
Evidence for PS localization
Functions
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Also regulates the migration of developing neurons (PubMed). Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in KCC2B_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 33.3333 | 4 | no |
| GO:0046872 | metal ion binding | 31.9444 | 5 | no |
| GO:0043168 | anion binding | 30.5556 | 4 | yes |
| GO:0000166 | nucleotide binding | 25.0000 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 25.0000 | 5 | yes |
| GO:0019900 | kinase binding | 25.0000 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.6111 | 6 | yes |
| GO:0032555 | purine ribonucleotide binding | 23.6111 | 4 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 22.2222 | 5 | yes |
| GO:0042803 | protein homodimerization activity | 22.2222 | 4 | yes |
| GO:0003723 | RNA binding | 22.2222 | 4 | no |
| GO:0019901 | protein kinase binding | 22.2222 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.8333 | 4 | yes |
| GO:0005524 | ATP binding | 19.4444 | 5 | yes |
| GO:0003779 | actin binding | 15.2778 | 4 | yes |
| GO:0016301 | kinase activity | 11.1111 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 11.1111 | 4 | yes |
| GO:0004674 | protein serine/threonine kinase activity | 9.7222 | 4 | yes |
| GO:0106310 | protein serine kinase activity | 9.7222 | 4 | yes |
| GO:0004683 | calmodulin-dependent protein kinase activity | 6.9444 | 5 | yes |
| GO:0009931 | calcium-dependent protein serine/threonine kinase activity | 2.7778 | 5 | yes |
| GO:0010857 | calcium-dependent protein kinase activity | 2.7778 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in KCC2B_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 63.8889 | 4 | yes |
| GO:0010646 | regulation of cell communication | 62.5000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 56.9444 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 55.5556 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 52.7778 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 52.7778 | 4 | no |
| GO:0009966 | regulation of signal transduction | 51.3889 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | yes |
| GO:0022607 | cellular component assembly | 44.4444 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 41.6667 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 41.6667 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.2778 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 38.8889 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 38.8889 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 38.8889 | 5 | no |
| GO:0031399 | regulation of protein modification process | 37.5000 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 37.5000 | 4 | no |
| GO:0010468 | regulation of gene expression | 37.5000 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 37.5000 | 5 | no |
| GO:0051049 | regulation of transport | 36.1111 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 36.1111 | 5 | no |
| GO:0006996 | organelle organization | 34.7222 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 34.7222 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 34.7222 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 31.9444 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 30.5556 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 30.5556 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 30.5556 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.5556 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 29.1667 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 27.7778 | 5 | yes |
| GO:0008104 | protein localization | 27.7778 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 27.7778 | 7 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.7778 | 6 | no |
| GO:0043933 | protein-containing complex organization | 27.7778 | 4 | no |
| GO:0043269 | regulation of monoatomic ion transport | 26.3889 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 26.3889 | 6 | yes |
| GO:0001932 | regulation of protein phosphorylation | 26.3889 | 7 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.3889 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.3889 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 25.0000 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 25.0000 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.6111 | 4 | yes |
| GO:0036211 | protein modification process | 23.6111 | 4 | yes |
| GO:0043412 | macromolecule modification | 23.6111 | 4 | yes |
| GO:0044057 | regulation of system process | 23.6111 | 4 | yes |
| GO:0030030 | cell projection organization | 23.6111 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 23.6111 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.6111 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 23.6111 | 5 | no |
| GO:0023057 | negative regulation of signaling | 23.6111 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 23.6111 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 23.6111 | 4 | no |
| GO:0010959 | regulation of metal ion transport | 22.2222 | 6 | yes |
| GO:0050807 | regulation of synapse organization | 22.2222 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 22.2222 | 7 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.2222 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.2222 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 22.2222 | 5 | no |
| GO:0032880 | regulation of protein localization | 22.2222 | 5 | no |
| GO:0051338 | regulation of transferase activity | 22.2222 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 22.2222 | 5 | no |
| GO:0034762 | regulation of transmembrane transport | 22.2222 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 20.8333 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 20.8333 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 20.8333 | 5 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 20.8333 | 6 | no |
| GO:0042327 | positive regulation of phosphorylation | 20.8333 | 8 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 20.8333 | 7 | no |
| GO:0009894 | regulation of catabolic process | 20.8333 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.8333 | 6 | no |
| GO:0050890 | cognition | 20.8333 | 4 | no |
| GO:0043549 | regulation of kinase activity | 20.8333 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 19.4444 | 4 | yes |
| GO:0051924 | regulation of calcium ion transport | 19.4444 | 7 | yes |
| GO:0048168 | regulation of neuronal synaptic plasticity | 18.0556 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 18.0556 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 15.2778 | 7 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 15.2778 | 4 | yes |
| GO:0051960 | regulation of nervous system development | 15.2778 | 5 | yes |
| GO:0060284 | regulation of cell development | 15.2778 | 5 | yes |
| GO:0045597 | positive regulation of cell differentiation | 13.8889 | 5 | yes |
| GO:0050767 | regulation of neurogenesis | 13.8889 | 6 | yes |
| GO:0090257 | regulation of muscle system process | 13.8889 | 5 | yes |
| GO:0016310 | phosphorylation | 12.5000 | 5 | yes |
| GO:0031346 | positive regulation of cell projection organization | 12.5000 | 6 | yes |
| GO:0099175 | regulation of postsynapse organization | 12.5000 | 6 | yes |
| GO:0006468 | protein phosphorylation | 11.1111 | 5 | yes |
| GO:0010720 | positive regulation of cell development | 11.1111 | 6 | yes |
| GO:0048169 | regulation of long-term neuronal synaptic plasticity | 11.1111 | 5 | yes |
| GO:0051962 | positive regulation of nervous system development | 11.1111 | 5 | yes |
| GO:0007399 | nervous system development | 9.7222 | 4 | yes |
| GO:0030334 | regulation of cell migration | 9.7222 | 5 | yes |
| GO:0050769 | positive regulation of neurogenesis | 9.7222 | 6 | yes |
| GO:2000145 | regulation of cell motility | 9.7222 | 4 | yes |
| GO:0022604 | regulation of cell morphogenesis | 8.3333 | 5 | yes |
| GO:0043502 | regulation of muscle adaptation | 6.9444 | 4 | yes |
| GO:0046777 | protein autophosphorylation | 6.9444 | 6 | yes |
| GO:0060998 | regulation of dendritic spine development | 6.9444 | 4 | yes |
| GO:0060999 | positive regulation of dendritic spine development | 6.9444 | 5 | yes |
| GO:0018105 | peptidyl-serine phosphorylation | 5.5556 | 6 | yes |
| GO:0018193 | peptidyl-amino acid modification | 5.5556 | 5 | yes |
| GO:0018209 | peptidyl-serine modification | 5.5556 | 6 | yes |
| GO:0050773 | regulation of dendrite development | 5.5556 | 4 | yes |
| GO:0061001 | regulation of dendritic spine morphogenesis | 5.5556 | 5 | yes |
| GO:0090128 | regulation of synapse maturation | 5.5556 | 4 | yes |
| GO:0010976 | positive regulation of neuron projection development | 4.1667 | 7 | yes |
| GO:0014733 | regulation of skeletal muscle adaptation | 4.1667 | 5 | yes |
| GO:0048814 | regulation of dendrite morphogenesis | 4.1667 | 5 | yes |
| GO:0051823 | regulation of synapse structural plasticity | 4.1667 | 6 | yes |
| GO:0090129 | positive regulation of synapse maturation | 4.1667 | 5 | yes |
| GO:2001222 | regulation of neuron migration | 4.1667 | 6 | yes |
| GO:0010770 | positive regulation of cell morphogenesis | 2.7778 | 6 | yes |
| GO:0050775 | positive regulation of dendrite morphogenesis | 2.7778 | 6 | yes |
| GO:0061003 | positive regulation of dendritic spine morphogenesis | 2.7778 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ARC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PRS8_HUMAN | [view interactions] | Low throughput | no | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FLII_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ACTN4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDC20_HUMAN | [view interactions] | Low throughput | no | no |
| CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTPRR_HUMAN | [view interactions] | Low throughput | no | yes |
| NCOR2_HUMAN | [view interactions] | Low throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MPDZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRID2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGR_HUMAN | [view interactions] | High throughput | no | no |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE4A_HUMAN | [view interactions] | High throughput | no | no |
| ITPI2_HUMAN | [view interactions] | High throughput | no | yes |
| STRN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITPR2_HUMAN | [view interactions] | High throughput | no | yes |
| ITPR3_HUMAN | [view interactions] | High throughput | no | yes |
| SLMAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PNMA2_HUMAN | [view interactions] | High throughput | no | yes |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| M3K2_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEUL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| RIMS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| SMYD3_HUMAN | [view interactions] | High throughput | no | yes |
| BACH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFOX2_HUMAN | [view interactions] | High throughput | no | yes |
| KR10B_HUMAN | [view interactions] | High throughput | no | no |
| RAP2B_HUMAN | [view interactions] | High throughput | no | no |
| RL11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP5B1_HUMAN | [view interactions] | High throughput | no | yes |
| KR195_HUMAN | [view interactions] | High throughput | no | no |
| KR197_HUMAN | [view interactions] | High throughput | no | no |
| SPRY7_HUMAN | [view interactions] | High throughput | no | yes |
| TTC5_HUMAN | [view interactions] | High throughput | no | yes |
| RBPMS_HUMAN | [view interactions] | High throughput | no | no |
| KPBB_HUMAN | [view interactions] | High throughput | no | no |
| POP5_HUMAN | [view interactions] | High throughput | no | no |
| MED18_HUMAN | [view interactions] | High throughput | no | yes |
| MO4L1_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| RM11_HUMAN | [view interactions] | High throughput | no | yes |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| TANK_HUMAN | [view interactions] | High throughput | no | yes |
| THB_HUMAN | [view interactions] | High throughput | no | no |
| RXRG_HUMAN | [view interactions] | High throughput | no | no |
| MVP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEM4G_HUMAN | [view interactions] | High throughput | no | yes |
| CCM2L_HUMAN | [view interactions] | High throughput | no | no |
| MGT5B_HUMAN | [view interactions] | High throughput | no | no |
| F1712_HUMAN | [view interactions] | High throughput | no | no |
| ZBT32_HUMAN | [view interactions] | High throughput | no | yes |
| PNKP_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO3_HUMAN | [view interactions] | High throughput | no | yes |
| ARSA_HUMAN | [view interactions] | High throughput | no | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO2_HUMAN | [view interactions] | High throughput | no | yes |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| MO4L2_HUMAN | [view interactions] | High throughput | no | yes |
| ZMYM5_HUMAN | [view interactions] | High throughput | no | yes |
| DUS1L_HUMAN | [view interactions] | High throughput | no | yes |
| KRT86_HUMAN | [view interactions] | High throughput | no | no |
| RPC3_HUMAN | [view interactions] | High throughput | no | yes |
| KRA62_HUMAN | [view interactions] | High throughput | no | no |
| KRA11_HUMAN | [view interactions] | High throughput | no | no |
| KR193_HUMAN | [view interactions] | High throughput | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| ARMC1_HUMAN | [view interactions] | High throughput | no | yes |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
| DGUOK_HUMAN | [view interactions] | High throughput | no | yes |
| KTU_HUMAN | [view interactions] | High throughput | no | yes |
| ASAH1_HUMAN | [view interactions] | High throughput | no | yes |
| LIPH_HUMAN | [view interactions] | High throughput | no | no |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM42_HUMAN | [view interactions] | High throughput | no | yes |
| CF141_HUMAN | [view interactions] | High throughput | no | no |
| ZN843_HUMAN | [view interactions] | High throughput | no | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INADL_HUMAN | [view interactions] | High throughput | no | no |
| KALRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| DNAL4_HUMAN | [view interactions] | High throughput | no | yes |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| E41LB_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| TCPQM_HUMAN | [view interactions] | High throughput | no | no |
| RDH8_HUMAN | [view interactions] | High throughput | no | no |
| F163B_HUMAN | [view interactions] | High throughput | no | yes |
| EFMT2_HUMAN | [view interactions] | High throughput | no | yes |
| NAA11_HUMAN | [view interactions] | High throughput | no | no |
| VCIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRC2_HUMAN | [view interactions] | High throughput | no | no |
| MAGA9_HUMAN | [view interactions] | High throughput | no | no |
| SHSA6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAP10_HUMAN | [view interactions] | High throughput | no | no |
| WDR5B_HUMAN | [view interactions] | High throughput | no | yes |
| CT096_HUMAN | [view interactions] | High throughput | no | yes |
| TRAT1_HUMAN | [view interactions] | High throughput | no | no |
| PIGH_HUMAN | [view interactions] | High throughput | no | yes |
| DUS4L_HUMAN | [view interactions] | High throughput | no | yes |
| F170A_HUMAN | [view interactions] | High throughput | no | no |
| ZN397_HUMAN | [view interactions] | High throughput | no | yes |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| ZN764_HUMAN | [view interactions] | High throughput | no | no |
| TPC2L_HUMAN | [view interactions] | High throughput | no | yes |
| AAKG2_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PALD_HUMAN | [view interactions] | High throughput | no | yes |
| ZSCA1_HUMAN | [view interactions] | High throughput | no | yes |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| ELP3_HUMAN | [view interactions] | High throughput | no | no |
| TTLL1_HUMAN | [view interactions] | High throughput | no | yes |
| PADI4_HUMAN | [view interactions] | High throughput | no | no |
| ANGL7_HUMAN | [view interactions] | High throughput | no | no |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBAR2_HUMAN | [view interactions] | High throughput | no | no |
| CK2N1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH21A_HUMAN | [view interactions] | High throughput | no | no |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TF2H4_HUMAN | [view interactions] | High throughput | no | no |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| PLCE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| CD22_HUMAN | [view interactions] | High throughput | no | no |
| ACY1_HUMAN | [view interactions] | High throughput | no | no |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |