PPP5_HUMAN
Evidence for PS localization
Functions
Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC and TP53BP1 (PubMed, PubMed, PubMed). Inhibits ASK1/MAP3K5-mediated apoptosis induced by oxidative stress (PubMed). Plays a positive role in adipogenesis, mainly through the dephosphorylation and activation of PPARG transactivation function . Also dephosphorylates and inhibits the anti-adipogenic effect of NR3C1 . Regulates the circadian rhythms, through the dephosphorylation and activation of CSNK1E (PubMed). May modulate TGF-beta signaling pathway by the regulation of SMAD3 phosphorylation and protein expression levels (PubMed). Dephosphorylates and may play a role in the regulation of TAU/MAPT (PubMed). Through their dephosphorylation, may play a role in the regulation of ions channels such as KCNH2 . Dephosphorylate FNIP1, disrupting interaction with HSP90AA1/Hsp90 (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PPP5_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 48.0519 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 46.7532 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 46.7532 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 40.2597 | 5 | yes |
| GO:0005524 | ATP binding | 38.9610 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 38.9610 | 5 | yes |
| GO:0003723 | RNA binding | 35.0649 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 27.2727 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 27.2727 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 27.2727 | 6 | no |
| GO:0046872 | metal ion binding | 20.7792 | 4 | yes |
| GO:0048156 | tau protein binding | 11.6883 | 4 | yes |
| GO:0051879 | Hsp90 protein binding | 10.3896 | 4 | yes |
| GO:0042578 | phosphoric ester hydrolase activity | 7.7922 | 4 | yes |
| GO:0004722 | protein serine/threonine phosphatase activity | 6.4935 | 4 | yes |
| GO:0016791 | phosphatase activity | 6.4935 | 5 | yes |
| GO:0043531 | ADP binding | 2.5974 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PPP5_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 68.8312 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 67.5325 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 66.2338 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 66.2338 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 64.9351 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 58.4416 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 55.8442 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 53.2468 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 53.2468 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 51.9481 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 51.9481 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 50.6494 | 5 | no |
| GO:0010468 | regulation of gene expression | 49.3506 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 49.3506 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 45.4545 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.4545 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 44.1558 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 44.1558 | 5 | no |
| GO:0009966 | regulation of signal transduction | 44.1558 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 36.3636 | 4 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 36.3636 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 35.0649 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 35.0649 | 6 | no |
| GO:0022607 | cellular component assembly | 35.0649 | 4 | no |
| GO:0043412 | macromolecule modification | 33.7662 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 33.7662 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 33.7662 | 6 | no |
| GO:0036211 | protein modification process | 33.7662 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 31.1688 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.1688 | 5 | no |
| GO:0031399 | regulation of protein modification process | 31.1688 | 6 | no |
| GO:0043085 | positive regulation of catalytic activity | 31.1688 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 31.1688 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 31.1688 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 31.1688 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 29.8701 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 29.8701 | 6 | no |
| GO:0060341 | regulation of cellular localization | 29.8701 | 4 | no |
| GO:0033043 | regulation of organelle organization | 29.8701 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 28.5714 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 28.5714 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 28.5714 | 6 | no |
| GO:0043933 | protein-containing complex organization | 28.5714 | 4 | no |
| GO:0006996 | organelle organization | 28.5714 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.5714 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 27.2727 | 5 | no |
| GO:0010941 | regulation of cell death | 27.2727 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.2727 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 27.2727 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 25.9740 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.9740 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.9740 | 5 | no |
| GO:0032880 | regulation of protein localization | 25.9740 | 5 | no |
| GO:0051052 | regulation of DNA metabolic process | 24.6753 | 5 | no |
| GO:0009894 | regulation of catabolic process | 24.6753 | 4 | no |
| GO:0050821 | protein stabilization | 24.6753 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 23.3766 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 23.3766 | 7 | no |
| GO:0051338 | regulation of transferase activity | 23.3766 | 4 | no |
| GO:0030162 | regulation of proteolysis | 23.3766 | 6 | no |
| GO:0051049 | regulation of transport | 23.3766 | 4 | no |
| GO:0071310 | cellular response to organic substance | 23.3766 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 23.3766 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 23.3766 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 22.0779 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 22.0779 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 22.0779 | 6 | no |
| GO:0031329 | regulation of cellular catabolic process | 22.0779 | 5 | no |
| GO:0080134 | regulation of response to stress | 22.0779 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 22.0779 | 6 | no |
| GO:0051054 | positive regulation of DNA metabolic process | 22.0779 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 22.0779 | 6 | no |
| GO:0008104 | protein localization | 22.0779 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 20.7792 | 7 | no |
| GO:0031401 | positive regulation of protein modification process | 20.7792 | 7 | no |
| GO:0044087 | regulation of cellular component biogenesis | 20.7792 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 16.8831 | 4 | yes |
| GO:0014070 | response to organic cyclic compound | 16.8831 | 4 | yes |
| GO:0016070 | RNA metabolic process | 15.5844 | 5 | yes |
| GO:0006974 | cellular response to DNA damage stimulus | 11.6883 | 4 | yes |
| GO:0033993 | response to lipid | 11.6883 | 4 | yes |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 10.3896 | 4 | yes |
| GO:0000165 | MAPK cascade | 10.3896 | 4 | yes |
| GO:0006259 | DNA metabolic process | 10.3896 | 4 | yes |
| GO:0010038 | response to metal ion | 10.3896 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 9.0909 | 4 | yes |
| GO:0009059 | macromolecule biosynthetic process | 9.0909 | 4 | yes |
| GO:0018130 | heterocycle biosynthetic process | 9.0909 | 4 | yes |
| GO:0019438 | aromatic compound biosynthetic process | 9.0909 | 4 | yes |
| GO:0006281 | DNA repair | 7.7922 | 5 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 7.7922 | 4 | yes |
| GO:0006470 | protein dephosphorylation | 6.4935 | 5 | yes |
| GO:0010288 | response to lead ion | 6.4935 | 5 | yes |
| GO:0016311 | dephosphorylation | 6.4935 | 5 | yes |
| GO:0070262 | peptidyl-serine dephosphorylation | 5.1948 | 6 | yes |
| GO:0006302 | double-strand break repair | 5.1948 | 6 | yes |
| GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 5.1948 | 6 | yes |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 5.1948 | 7 | yes |
| GO:0097659 | nucleic acid-templated transcription | 3.8961 | 6 | yes |
| GO:0006351 | DNA-templated transcription | 3.8961 | 7 | yes |
| GO:0032774 | RNA biosynthetic process | 3.8961 | 5 | yes |
| GO:0035970 | peptidyl-threonine dephosphorylation | 3.8961 | 6 | yes |
| GO:0043279 | response to alkaloid | 3.8961 | 5 | yes |
| GO:0070542 | response to fatty acid | 2.5974 | 4 | yes |
| GO:1904550 | response to arachidonic acid | 2.5974 | 5 | yes |
| GO:0014072 | response to isoquinoline alkaloid | 2.5974 | 5 | yes |
| GO:0043278 | response to morphine | 2.5974 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in PPP5_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 2.5974 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ESR2_HUMAN | [view interactions] | Low throughput | no | no |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| PP2AA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | Low throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHRD1_HUMAN | [view interactions] | Low throughput | no | yes |
| CRY2_HUMAN | [view interactions] | Low throughput | no | yes |
| CRY1_HUMAN | [view interactions] | Low throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| P2R3A_HUMAN | [view interactions] | Low throughput | no | yes |
| CDC27_HUMAN | [view interactions] | Low throughput | no | yes |
| CDC16_HUMAN | [view interactions] | Low throughput | no | yes |
| TP53B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNA12_HUMAN | [view interactions] | Low throughput | no | no |
| M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
| HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | Low throughput | no | yes |
| KC1D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GNA13_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDK20_HUMAN | [view interactions] | Low throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| 5HT2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP49_HUMAN | [view interactions] | High throughput | no | yes |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| ULK2_HUMAN | [view interactions] | High throughput | no | yes |
| WIPI2_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD37L_HUMAN | [view interactions] | High throughput | no | yes |
| IRS4_HUMAN | [view interactions] | High throughput | no | no |
| TEBP_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| ABCF2_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOL9_HUMAN | [view interactions] | High throughput | no | no |
| AGO3_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| AGO1_HUMAN | [view interactions] | High throughput | no | no |
| KSR2_HUMAN | [view interactions] | High throughput | no | yes |
| DPOD2_HUMAN | [view interactions] | High throughput | no | no |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP5_HUMAN | [view interactions] | High throughput | no | yes |
| MRCKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP3_HUMAN | [view interactions] | High throughput | no | no |
| H90B4_HUMAN | [view interactions] | High throughput | no | no |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| FLII_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| LRRC1_HUMAN | [view interactions] | High throughput | no | yes |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS905_HUMAN | [view interactions] | High throughput | no | no |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| CNTLN_HUMAN | [view interactions] | High throughput | no | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAPCG_HUMAN | [view interactions] | High throughput | no | no |
| GRK6_HUMAN | [view interactions] | High throughput | no | yes |
| IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| LIMK2_HUMAN | [view interactions] | High throughput | no | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| CDK13_HUMAN | [view interactions] | High throughput | no | no |
| LRRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MK15_HUMAN | [view interactions] | High throughput | no | no |
| KPSH2_HUMAN | [view interactions] | High throughput | no | no |
| TSSK2_HUMAN | [view interactions] | High throughput | no | no |
| DYRK4_HUMAN | [view interactions] | High throughput | no | no |
| LATS2_HUMAN | [view interactions] | High throughput | no | yes |
| XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| CDK18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD1_HUMAN | [view interactions] | High throughput | no | yes |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPNE1_HUMAN | [view interactions] | High throughput | no | no |
| CPNE2_HUMAN | [view interactions] | High throughput | no | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRGR_HUMAN | [view interactions] | High throughput | no | no |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| BPHL_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBBP6_HUMAN | [view interactions] | High throughput | no | yes |
| UBP45_HUMAN | [view interactions] | High throughput | no | yes |
| FLCN_HUMAN | [view interactions] | High throughput | no | yes |
| DUS8_HUMAN | [view interactions] | High throughput | no | no |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| RAB41_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| YAF2_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR7_HUMAN | [view interactions] | High throughput | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| DJB13_HUMAN | [view interactions] | High throughput | no | no |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNJC8_HUMAN | [view interactions] | High throughput | no | yes |
| M4K1_HUMAN | [view interactions] | High throughput | no | no |
| GADL1_HUMAN | [view interactions] | High throughput | no | no |
| INTU_HUMAN | [view interactions] | High throughput | no | yes |
| FSCN3_HUMAN | [view interactions] | High throughput | no | no |
| DEFI8_HUMAN | [view interactions] | High throughput | no | yes |
| FA83F_HUMAN | [view interactions] | High throughput | no | no |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| PA24A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPNE4_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITBP2_HUMAN | [view interactions] | High throughput | no | no |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRP44_HUMAN | [view interactions] | High throughput | no | yes |
| FETUA_HUMAN | [view interactions] | High throughput | no | no |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABHEA_HUMAN | [view interactions] | High throughput | no | yes |
| 5MP1_HUMAN | [view interactions] | High throughput | no | no |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| PSF3_HUMAN | [view interactions] | High throughput | no | yes |
| GSHB_HUMAN | [view interactions] | High throughput | no | no |
| PNCB_HUMAN | [view interactions] | High throughput | no | no |
| PA1B2_HUMAN | [view interactions] | High throughput | no | yes |
| PAPS1_HUMAN | [view interactions] | High throughput | no | yes |
| PLD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYRG1_HUMAN | [view interactions] | High throughput | no | no |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| DFFA_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUT_HUMAN | [view interactions] | High throughput | no | yes |
| MINP1_HUMAN | [view interactions] | High throughput | no | yes |
| NOL10_HUMAN | [view interactions] | High throughput | no | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| TATD1_HUMAN | [view interactions] | High throughput | no | yes |
| GCSP_HUMAN | [view interactions] | High throughput | no | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH1_HUMAN | [view interactions] | High throughput | no | yes |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM8_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHD1_HUMAN | [view interactions] | High throughput | no | no |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| H2B2E_HUMAN | [view interactions] | Computational | no | yes |
| HERC2_HUMAN | [view interactions] | Computational | no | yes |
| TCPB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| H2B1N_HUMAN | [view interactions] | Computational | no | yes |
| SUMO1_HUMAN | [view interactions] | Computational | no | yes |
| H2B1J_HUMAN | [view interactions] | Computational | no | yes |
| TCPG_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| H31T_HUMAN | [view interactions] | Computational | no | yes |
| RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| NBN_HUMAN | [view interactions] | Computational | no | yes |
| KSR1_HUMAN | [view interactions] | Computational | no | yes |
| MRE11_HUMAN | [view interactions] | Computational | no | yes |
| ATM_HUMAN | [view interactions] | Computational | no | yes |
| RN168_HUMAN | [view interactions] | Computational | no | no |
| H2B1D_HUMAN | [view interactions] | Computational | no | yes |
| H2B1M_HUMAN | [view interactions] | Computational | no | yes |
| NSD2_HUMAN | [view interactions] | Computational | no | yes |
| RAD50_HUMAN | [view interactions] | Computational | no | yes |
| UB2V2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| TCPE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UBE2N_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| H2B1L_HUMAN | [view interactions] | Computational | no | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TSC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PSMG2_HUMAN | [view interactions] | Computational | no | yes |
| H2AX_HUMAN | [view interactions] | Computational | no | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TCPA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| H2B1A_HUMAN | [view interactions] | Computational | no | no |
| PIAS4_HUMAN | [view interactions] | Computational | no | yes |
| PSMG1_HUMAN | [view interactions] | Computational | no | yes |
| H2B1B_HUMAN | [view interactions] | Computational | no | yes |
| TCPH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| H2BFS_HUMAN | [view interactions] | Computational | no | yes |
| KAT5_HUMAN | [view interactions] | Computational | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| H2B1H_HUMAN | [view interactions] | Computational | no | yes |
| MDC1_HUMAN | [view interactions] | Computational | no | yes |
| PPID_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RNF8_HUMAN | [view interactions] | Computational | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| H2B1K_HUMAN | [view interactions] | Computational | no | yes |
| H2B1O_HUMAN | [view interactions] | Computational | no | yes |
| FKBP4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |