Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KS6B1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex 1 (mTORC1) leads to dissociation from the EIF3 complex and activation. The active form then phosphorylates and activates several substrates in the pre-initiation complex, including the EIF2B complex and the cap-binding complex component EIF4B. Also controls translation initiation by phosphorylating a negative regulator of EIF4A, PDCD4, targeting it for ubiquitination and subsequent proteolysis. Promotes initiation of the pioneer round of protein synthesis by phosphorylating POLDIP3/SKAR. In response to IGF1, activates translation elongation by phosphorylating EEF2 kinase (EEF2K), which leads to its inhibition and thus activation of EEF2. Also plays a role in feedback regulation of mTORC2 by mTORC1 by phosphorylating RICTOR, resulting in the inhibition of mTORC2 and AKT1 signaling. Mediates cell survival by phosphorylating the pro-apoptotic protein BAD and suppressing its pro-apoptotic function. Phosphorylates mitochondrial URI1 leading to dissociation of a URI1-PPP1CC complex. The free mitochondrial PPP1CC can then dephosphorylate RPS6KB1 at Thr-412, which is proposed to be a negative feedback mechanism for the RPS6KB1 anti-apoptotic function. Mediates TNF-alpha-induced insulin resistance by phosphorylating IRS1 at multiple serine residues, resulting in accelerated degradation of IRS1. In cells lacking functional TSC1-2 complex, constitutively phosphorylates and inhibits GSK3B. May be involved in cytoskeletal rearrangement through binding to neurabin. Phosphorylates and activates the pyrimidine biosynthesis enzyme CAD, downstream of MTOR (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Following activation by mTORC1, phosphorylates EPRS and thereby plays a key role in fatty acid uptake by adipocytes and also most probably in interferon-gamma-induced translation inhibition (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI001214 DOC_WD40_RPTOR_TOS_1 DOC 28 33 -
ELMI001214 DOC_WD40_RPTOR_TOS_1 DOC 28 33 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in KS6B1_HUMAN
GO:0000166 nucleotide binding 50.0000 4 yes
GO:0017076 purine nucleotide binding 50.0000 5 yes
GO:0032555 purine ribonucleotide binding 48.4375 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 48.4375 4 yes
GO:0043168 anion binding 48.4375 4 yes
GO:0030554 adenyl nucleotide binding 46.8750 6 yes
GO:0005524 ATP binding 45.3125 5 yes
GO:0032559 adenyl ribonucleotide binding 45.3125 5 yes
GO:0016301 kinase activity 35.9375 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 35.9375 4 yes
GO:0003723 RNA binding 28.1250 4 no
GO:0004674 protein serine/threonine kinase activity 26.5625 4 yes
GO:0043169 cation binding 26.5625 4 no
GO:0046872 metal ion binding 26.5625 5 no
GO:0019900 kinase binding 25.0000 4 no
GO:0106310 protein serine kinase activity 23.4375 4 yes
GO:0019901 protein kinase binding 23.4375 5 no
GO:0019902 phosphatase binding 15.6250 4 yes
GO:0019903 protein phosphatase binding 10.9375 5 yes
GO:0004711 ribosomal protein S6 kinase activity 6.2500 5 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 6.2500 4 yes
GO:0051721 protein phosphatase 2A binding 6.2500 6 yes
GO:0030165 PDZ domain binding 4.6875 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KS6B1_HUMAN
GO:0048522 positive regulation of cellular process 82.8125 4 yes
GO:0031323 regulation of cellular metabolic process 75.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 73.4375 4 yes
GO:0048523 negative regulation of cellular process 71.8750 4 yes
GO:0080090 regulation of primary metabolic process 71.8750 4 yes
GO:0009889 regulation of biosynthetic process 64.0625 4 yes
GO:0009893 positive regulation of metabolic process 64.0625 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 64.0625 5 yes
GO:0010646 regulation of cell communication 64.0625 4 yes
GO:0031326 regulation of cellular biosynthetic process 64.0625 5 yes
GO:0009966 regulation of signal transduction 59.3750 4 yes
GO:0010468 regulation of gene expression 57.8125 6 yes
GO:0010604 positive regulation of macromolecule metabolic process 57.8125 5 yes
GO:0031325 positive regulation of cellular metabolic process 57.8125 5 yes
GO:0051246 regulation of protein metabolic process 53.1250 5 yes
GO:0043412 macromolecule modification 51.5625 4 yes
GO:0036211 protein modification process 50.0000 4 yes
GO:1902531 regulation of intracellular signal transduction 50.0000 5 yes
GO:0048584 positive regulation of response to stimulus 48.4375 4 yes
GO:0009892 negative regulation of metabolic process 48.4375 4 no
GO:0051128 regulation of cellular component organization 48.4375 4 no
GO:0010647 positive regulation of cell communication 46.8750 5 yes
GO:0023056 positive regulation of signaling 46.8750 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 45.3125 5 no
GO:0009891 positive regulation of biosynthetic process 43.7500 5 yes
GO:0009967 positive regulation of signal transduction 43.7500 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 43.7500 6 yes
GO:0031328 positive regulation of cellular biosynthetic process 43.7500 6 yes
GO:0006796 phosphate-containing compound metabolic process 42.1875 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 42.1875 5 no
GO:0031324 negative regulation of cellular metabolic process 42.1875 5 no
GO:0009894 regulation of catabolic process 40.6250 4 no
GO:0010648 negative regulation of cell communication 39.0625 5 yes
GO:0016310 phosphorylation 39.0625 5 yes
GO:0023057 negative regulation of signaling 39.0625 4 yes
GO:0042127 regulation of cell population proliferation 39.0625 4 yes
GO:0009968 negative regulation of signal transduction 37.5000 5 yes
GO:0042981 regulation of apoptotic process 37.5000 5 yes
GO:0043067 regulation of programmed cell death 37.5000 4 yes
GO:0048585 negative regulation of response to stimulus 37.5000 4 yes
GO:0051049 regulation of transport 37.5000 4 yes
GO:0071310 cellular response to organic substance 37.5000 4 yes
GO:0006468 protein phosphorylation 34.3750 5 yes
GO:0010243 response to organonitrogen compound 34.3750 4 yes
GO:0051247 positive regulation of protein metabolic process 34.3750 6 yes
GO:1901701 cellular response to oxygen-containing compound 34.3750 4 yes
GO:1902533 positive regulation of intracellular signal transduction 34.3750 6 yes
GO:0051252 regulation of RNA metabolic process 32.8125 5 no
GO:0009890 negative regulation of biosynthetic process 32.8125 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 32.8125 6 no
GO:0031327 negative regulation of cellular biosynthetic process 32.8125 6 no
GO:0051094 positive regulation of developmental process 31.2500 4 yes
GO:0051726 regulation of cell cycle 31.2500 4 yes
GO:0031399 regulation of protein modification process 31.2500 6 no
GO:0006355 regulation of DNA-templated transcription 29.6875 7 no
GO:0045595 regulation of cell differentiation 29.6875 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 29.6875 5 no
GO:2001141 regulation of RNA biosynthetic process 29.6875 6 no
GO:0019220 regulation of phosphate metabolic process 29.6875 6 no
GO:0051174 regulation of phosphorus metabolic process 29.6875 5 no
GO:0080134 regulation of response to stress 29.6875 4 no
GO:0033043 regulation of organelle organization 29.6875 5 no
GO:0008284 positive regulation of cell population proliferation 28.1250 5 yes
GO:0043066 negative regulation of apoptotic process 28.1250 6 yes
GO:0043069 negative regulation of programmed cell death 28.1250 5 yes
GO:0042325 regulation of phosphorylation 28.1250 7 no
GO:0051130 positive regulation of cellular component organization 28.1250 5 no
GO:0022607 cellular component assembly 28.1250 4 no
GO:0060341 regulation of cellular localization 28.1250 4 no
GO:0006915 apoptotic process 26.5625 4 yes
GO:0010608 post-transcriptional regulation of gene expression 26.5625 7 yes
GO:0018193 peptidyl-amino acid modification 26.5625 5 yes
GO:0030334 regulation of cell migration 26.5625 5 yes
GO:0043434 response to peptide hormone 26.5625 4 yes
GO:0071417 cellular response to organonitrogen compound 26.5625 4 yes
GO:0141124 intracellular signaling cassette 26.5625 4 yes
GO:1901699 cellular response to nitrogen compound 26.5625 4 yes
GO:2000145 regulation of cell motility 26.5625 4 yes
GO:0051240 positive regulation of multicellular organismal process 26.5625 4 no
GO:0009896 positive regulation of catabolic process 26.5625 5 no
GO:0010629 negative regulation of gene expression 26.5625 7 no
GO:0001932 regulation of protein phosphorylation 26.5625 7 no
GO:0006996 organelle organization 26.5625 4 no
GO:0008104 protein localization 26.5625 4 no
GO:0031329 regulation of cellular catabolic process 26.5625 5 no
GO:0006417 regulation of translation 25.0000 6 yes
GO:0010628 positive regulation of gene expression 25.0000 7 yes
GO:0014070 response to organic cyclic compound 25.0000 4 yes
GO:0006357 regulation of transcription by RNA polymerase II 25.0000 8 no
GO:0051248 negative regulation of protein metabolic process 25.0000 6 no
GO:0051338 regulation of transferase activity 25.0000 4 no
GO:0044087 regulation of cellular component biogenesis 25.0000 4 no
GO:0030335 positive regulation of cell migration 23.4375 6 yes
GO:0032868 response to insulin 23.4375 5 yes
GO:0032870 cellular response to hormone stimulus 23.4375 4 yes
GO:0040017 positive regulation of locomotion 23.4375 4 yes
GO:0071702 organic substance transport 23.4375 4 yes
GO:2000147 positive regulation of cell motility 23.4375 5 yes
GO:0090304 nucleic acid metabolic process 23.4375 4 no
GO:0043085 positive regulation of catalytic activity 23.4375 4 no
GO:0032880 regulation of protein localization 23.4375 5 no
GO:0071375 cellular response to peptide hormone stimulus 21.8750 5 yes
GO:0045597 positive regulation of cell differentiation 21.8750 5 no
GO:1902532 negative regulation of intracellular signal transduction 21.8750 6 no
GO:0002684 positive regulation of immune system process 21.8750 4 no
GO:0010562 positive regulation of phosphorus metabolic process 21.8750 6 no
GO:0031344 regulation of cell projection organization 21.8750 5 no
GO:0031401 positive regulation of protein modification process 21.8750 7 no
GO:0042327 positive regulation of phosphorylation 21.8750 8 no
GO:0045937 positive regulation of phosphate metabolic process 21.8750 7 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.8750 6 no
GO:0043933 protein-containing complex organization 21.8750 4 no
GO:0010506 regulation of autophagy 21.8750 6 no
GO:0051050 positive regulation of transport 21.8750 4 no
GO:0033993 response to lipid 20.3125 4 yes
GO:0045893 positive regulation of DNA-templated transcription 20.3125 8 no
GO:0051254 positive regulation of RNA metabolic process 20.3125 6 no
GO:0051336 regulation of hydrolase activity 20.3125 4 no
GO:1902680 positive regulation of RNA biosynthetic process 20.3125 7 no
GO:0006974 DNA damage response 20.3125 4 no
GO:0001934 positive regulation of protein phosphorylation 20.3125 8 no
GO:0043549 regulation of kinase activity 20.3125 5 no
GO:0010638 positive regulation of organelle organization 20.3125 6 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 20.3125 5 no
GO:0009059 macromolecule biosynthetic process 20.3125 4 no
GO:0032006 regulation of TOR signaling 18.7500 6 yes
GO:0032869 cellular response to insulin stimulus 18.7500 6 yes
GO:0050804 modulation of chemical synaptic transmission 18.7500 5 yes
GO:0050890 cognition 18.7500 4 yes
GO:0099177 regulation of trans-synaptic signaling 18.7500 4 yes
GO:0007346 regulation of mitotic cell cycle 17.1875 5 yes
GO:0034097 response to cytokine 17.1875 4 yes
GO:0034762 regulation of transmembrane transport 17.1875 4 yes
GO:0045787 positive regulation of cell cycle 17.1875 5 yes
GO:0045927 positive regulation of growth 17.1875 4 yes
GO:0071363 cellular response to growth factor stimulus 17.1875 4 yes
GO:0098657 import into cell 17.1875 4 yes
GO:1903432 regulation of TORC1 signaling 17.1875 7 yes
GO:0071407 cellular response to organic cyclic compound 15.6250 5 yes
GO:0018105 peptidyl-serine phosphorylation 14.0625 6 yes
GO:0018209 peptidyl-serine modification 14.0625 6 yes
GO:0071345 cellular response to cytokine stimulus 14.0625 5 yes
GO:0045931 positive regulation of mitotic cell cycle 12.5000 6 yes
GO:0071396 cellular response to lipid 12.5000 5 yes
GO:2001233 regulation of apoptotic signaling pathway 12.5000 5 yes
GO:2001234 negative regulation of apoptotic signaling pathway 12.5000 6 yes
GO:0032008 positive regulation of TOR signaling 10.9375 7 yes
GO:0046626 regulation of insulin receptor signaling pathway 10.9375 5 yes
GO:0048638 regulation of developmental growth 10.9375 4 yes
GO:1900076 regulation of cellular response to insulin stimulus 10.9375 4 yes
GO:1904263 positive regulation of TORC1 signaling 10.9375 8 yes
GO:0031929 TOR signaling 9.3750 4 yes
GO:0043200 response to amino acid 9.3750 4 yes
GO:0046627 negative regulation of insulin receptor signaling pathway 9.3750 6 yes
GO:0048545 response to steroid hormone 9.3750 4 yes
GO:0048660 regulation of smooth muscle cell proliferation 9.3750 5 yes
GO:0048661 positive regulation of smooth muscle cell proliferation 9.3750 6 yes
GO:0097305 response to alcohol 9.3750 4 yes
GO:1900077 negative regulation of cellular response to insulin stimulus 9.3750 5 yes
GO:1901654 response to ketone 9.3750 4 yes
GO:0002237 response to molecule of bacterial origin 7.8125 4 yes
GO:0007613 memory 7.8125 4 yes
GO:0010827 regulation of glucose transmembrane transport 7.8125 5 yes
GO:0031960 response to corticosteroid 7.8125 5 yes
GO:0032496 response to lipopolysaccharide 7.8125 4 yes
GO:0034612 response to tumor necrosis factor 7.8125 5 yes
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction 7.8125 5 yes
GO:0044772 mitotic cell cycle phase transition 7.8125 4 yes
GO:0045727 positive regulation of translation 7.8125 7 yes
GO:0046324 regulation of glucose import 7.8125 6 yes
GO:0048639 positive regulation of developmental growth 7.8125 5 yes
GO:1901655 cellular response to ketone 7.8125 5 yes
GO:2001236 regulation of extrinsic apoptotic signaling pathway 7.8125 6 yes
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 7.8125 7 yes
GO:0000082 G1/S transition of mitotic cell cycle 6.2500 5 yes
GO:0006446 regulation of translational initiation 6.2500 7 yes
GO:0006936 muscle contraction 6.2500 4 yes
GO:0006941 striated muscle contraction 6.2500 5 yes
GO:0007616 long-term memory 6.2500 5 yes
GO:0014910 regulation of smooth muscle cell migration 6.2500 6 yes
GO:0014911 positive regulation of smooth muscle cell migration 6.2500 7 yes
GO:0031670 cellular response to nutrient 6.2500 4 yes
GO:0034341 response to type II interferon 6.2500 5 yes
GO:0044843 cell cycle G1/S phase transition 6.2500 4 yes
GO:0051384 response to glucocorticoid 6.2500 6 yes
GO:0071346 cellular response to type II interferon 6.2500 6 yes
GO:0071383 cellular response to steroid hormone stimulus 6.2500 5 yes
GO:0001662 behavioral fear response 4.6875 4 yes
GO:0003009 skeletal muscle contraction 4.6875 6 yes
GO:0006869 lipid transport 4.6875 5 yes
GO:0009743 response to carbohydrate 4.6875 4 yes
GO:0033574 response to testosterone 4.6875 5 yes
GO:0043201 response to L-leucine 4.6875 4 yes
GO:0045948 positive regulation of translational initiation 4.6875 8 yes
GO:0071384 cellular response to corticosteroid stimulus 4.6875 6 yes
GO:0071385 cellular response to glucocorticoid stimulus 4.6875 7 yes
GO:0071548 response to dexamethasone 4.6875 5 yes
GO:0071549 cellular response to dexamethasone stimulus 4.6875 6 yes
GO:0009746 response to hexose 3.1250 6 yes
GO:0009749 response to glucose 3.1250 7 yes
GO:0014732 skeletal muscle atrophy 3.1250 5 yes
GO:0014891 striated muscle atrophy 3.1250 4 yes
GO:0015711 organic anion transport 3.1250 5 yes
GO:0015718 monocarboxylic acid transport 3.1250 7 yes
GO:0015849 organic acid transport 3.1250 5 yes
GO:0015908 fatty acid transport 3.1250 6 yes
GO:0015909 long-chain fatty acid transport 3.1250 7 yes
GO:0033762 response to glucagon 3.1250 5 yes
GO:0034284 response to monosaccharide 3.1250 5 yes
GO:0043501 skeletal muscle adaptation 3.1250 4 yes
GO:0044539 long-chain fatty acid import into cell 3.1250 5 yes
GO:0045471 response to ethanol 3.1250 5 yes
GO:0046942 carboxylic acid transport 3.1250 6 yes
GO:0048015 phosphatidylinositol-mediated signaling 3.1250 4 yes
GO:0048631 regulation of skeletal muscle tissue growth 3.1250 5 yes
GO:0048633 positive regulation of skeletal muscle tissue growth 3.1250 6 yes
GO:0048641 regulation of skeletal muscle tissue development 3.1250 5 yes
GO:0048643 positive regulation of skeletal muscle tissue development 3.1250 6 yes
GO:0140354 lipid import into cell 3.1250 6 yes
GO:1901861 regulation of muscle tissue development 3.1250 4 yes
GO:1901863 positive regulation of muscle tissue development 3.1250 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NEB1_HUMAN [view entry] [view interactions] Low throughput yes yes
RPTOR_HUMAN [view interactions] Low throughput no yes
2ABB_HUMAN [view interactions] Low throughput no yes
PYR1_HUMAN [view entry] [view interactions] Low throughput yes yes
COASY_HUMAN [view entry] [view interactions] Low throughput yes yes
IER5_HUMAN [view interactions] Low throughput no yes
RS6_HUMAN [view entry] [view interactions] Low throughput yes yes
PDPK1_HUMAN [view entry] [view interactions] Low throughput yes yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
EIF3B_HUMAN [view interactions] Low throughput no yes
MDM2_HUMAN [view entry] [view interactions] Low throughput yes yes
GLI1_HUMAN [view interactions] Low throughput no no
PHLP2_HUMAN [view interactions] Low throughput no yes
PHLP1_HUMAN [view interactions] Low throughput no yes
PDK1_HUMAN [view interactions] Low throughput no yes
KS6B1_HUMAN [view entry] [view interactions] Low throughput yes yes
MTOR_HUMAN [view entry] [view interactions] Low throughput yes yes
MAD1_HUMAN [view interactions] Low throughput no yes
MK08_HUMAN [view interactions] Low throughput no yes
TSC1_HUMAN [view entry] [view interactions] Low throughput yes yes
TSC2_HUMAN [view entry] [view interactions] Low throughput yes yes
RICTR_HUMAN [view interactions] Low throughput no yes
CSK2B_HUMAN [view entry] [view interactions] Low throughput yes yes
PDIP3_HUMAN [view interactions] Low throughput no no
RBX1_HUMAN [view entry] [view interactions] Low throughput yes no
TRAF4_HUMAN [view interactions] Low throughput no yes
XPO1_HUMAN [view entry] [view interactions] Low throughput yes yes
EIF3F_HUMAN [view interactions] Low throughput no yes
2ABA_HUMAN [view interactions] Low throughput no yes
PLD2_HUMAN [view interactions] Low throughput no yes
TERT_HUMAN [view interactions] Low throughput no no
KPCZ_HUMAN [view entry] [view interactions] Low throughput yes yes
EP300_HUMAN [view interactions] Low throughput no yes
KAT2B_HUMAN [view interactions] Low throughput no yes
NFAC1_HUMAN [view interactions] Low throughput no no
TRIB2_HUMAN [view interactions] Low throughput no yes
DDT4L_HUMAN [view interactions] Low throughput no no
IRS2_HUMAN [view interactions] Low throughput no yes
MXI1_HUMAN [view interactions] Low throughput no yes
PGFRB_HUMAN [view interactions] Low throughput no yes
UBP11_HUMAN [view interactions] Low throughput no yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
TBK1_HUMAN [view entry] [view interactions] Low throughput yes yes
EF2K_HUMAN [view entry] [view interactions] Low throughput yes no
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTS_HUMAN [view interactions] Low throughput no no
MK14_HUMAN [view interactions] Low throughput no yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
MK03_HUMAN [view entry] [view interactions] Low throughput yes yes
MK09_HUMAN [view interactions] Low throughput no yes
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
RMP_HUMAN [view interactions] Low throughput no yes
RHEB_HUMAN [view entry] [view interactions] Low throughput yes yes
NR1I2_HUMAN [view interactions] Low throughput no no
DPTOR_HUMAN [view interactions] Low throughput no no
PI42A_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
HD_HUMAN [view entry] [view interactions] Low throughput yes yes
SIN1_HUMAN [view interactions] Low throughput no yes
STAT1_HUMAN [view entry] [view interactions] Low throughput yes no
ASTRA_HUMAN [view interactions] High throughput no no
TETN_HUMAN [view interactions] High throughput no no
DPPA4_HUMAN [view interactions] High throughput no no
NCBP1_HUMAN [view interactions] High throughput no yes
PPP5_HUMAN [view entry] [view interactions] High throughput yes yes
PAK1_HUMAN [view entry] [view interactions] High throughput yes yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
4EBP1_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
IF4E_HUMAN [view entry] [view interactions] High throughput yes yes
CYFP1_HUMAN [view entry] [view interactions] High throughput yes yes
KI3L1_HUMAN [view interactions] High throughput no no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
STK11_HUMAN [view interactions] High throughput no yes
HOOK2_HUMAN [view interactions] High throughput no yes
EIF3C_HUMAN [view entry] [view interactions] High throughput yes yes
EIF3H_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
SQSTM_HUMAN [view interactions] High throughput no yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
APEX1_HUMAN [view interactions] High throughput no yes
GUAD_HUMAN [view entry] [view interactions] High throughput yes yes
TBB4A_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
NQO2_HUMAN [view interactions] High throughput no yes
SERPH_HUMAN [view interactions] High throughput no no
RIN2_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
KIT_HUMAN [view interactions] High throughput no no
RIR2_HUMAN [view interactions] High throughput no no
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
ABL1_HUMAN [view entry] [view interactions] High throughput yes yes
RB_HUMAN [view interactions] High throughput no yes
AKT2_HUMAN [view entry] [view interactions] High throughput yes yes
SGK2_HUMAN [view interactions] High throughput no yes
KS6A3_HUMAN [view entry] [view interactions] High throughput yes yes
KS6A1_HUMAN [view entry] [view interactions] High throughput yes yes
AKT3_HUMAN [view interactions] High throughput no yes
KS6A4_HUMAN [view interactions] High throughput no yes
KS6B2_HUMAN [view interactions] High throughput no yes
SGK3_HUMAN [view interactions] High throughput no yes
KS6A2_HUMAN [view interactions] High throughput no yes
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
KS6A6_HUMAN [view interactions] High throughput no yes
SGK1_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
BTK_HUMAN [view interactions] High throughput no no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
SRC_HUMAN [view entry] [view interactions] High throughput yes no
KSYK_HUMAN [view interactions] High throughput no no
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
FBX7_HUMAN [view interactions] High throughput no yes
BRE1B_HUMAN [view interactions] High throughput no yes
TIPRL_HUMAN [view interactions] High throughput no yes
PSD10_HUMAN [view entry] [view interactions] High throughput yes yes
PARN_HUMAN [view entry] [view interactions] High throughput yes yes
HS74L_HUMAN [view entry] [view interactions] High throughput yes no
SAP_HUMAN [view interactions] High throughput no yes
IMDH2_HUMAN [view interactions] High throughput no yes
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
RS12_HUMAN [view entry] [view interactions] High throughput yes yes
MCM5_HUMAN [view interactions] High throughput no no
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
NAA10_HUMAN [view interactions] High throughput no yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
CAZA1_HUMAN [view entry] [view interactions] High throughput yes yes
GFRA1_HUMAN [view interactions] High throughput no no
GTF2I_HUMAN [view interactions] High throughput no yes
ULA1_HUMAN [view entry] [view interactions] High throughput yes yes
BRE1A_HUMAN [view interactions] High throughput no yes
UBA3_HUMAN [view interactions] High throughput no yes
RAD50_HUMAN [view interactions] High throughput no yes
RCC2_HUMAN [view interactions] High throughput no no
DC1L1_HUMAN [view entry] [view interactions] High throughput yes yes
BICD1_HUMAN [view interactions] High throughput no yes
BICD2_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
RFA1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes