EIF3C_HUMAN
Evidence for PS localization
Functions
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed, PubMed, PubMed). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in EIF3C_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 51.5152 | 4 | yes |
| GO:0043169 | cation binding | 22.2222 | 4 | no |
| GO:0046872 | metal ion binding | 22.2222 | 5 | no |
| GO:0000166 | nucleotide binding | 21.2121 | 4 | no |
| GO:0017076 | purine nucleotide binding | 20.2020 | 5 | no |
| GO:0043168 | anion binding | 20.2020 | 4 | no |
| GO:0003743 | translation initiation factor activity | 9.0909 | 4 | yes |
| GO:0043022 | ribosome binding | 6.0606 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in EIF3C_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.5455 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 54.5455 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 53.5354 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 51.5152 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 50.5051 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 44.4444 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 42.4242 | 4 | yes |
| GO:0010468 | regulation of gene expression | 42.4242 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 42.4242 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 42.4242 | 5 | yes |
| GO:0010646 | regulation of cell communication | 39.3939 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 37.3737 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 35.3535 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.3434 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 34.3434 | 4 | no |
| GO:0022607 | cellular component assembly | 33.3333 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 32.3232 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.3131 | 5 | no |
| GO:0009059 | macromolecule biosynthetic process | 31.3131 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 29.2929 | 5 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 28.2828 | 4 | no |
| GO:0006996 | organelle organization | 28.2828 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 27.2727 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 27.2727 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 27.2727 | 6 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 27.2727 | 6 | yes |
| GO:0042981 | regulation of apoptotic process | 27.2727 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 27.2727 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 27.2727 | 5 | no |
| GO:0006412 | translation | 25.2525 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.2424 | 4 | no |
| GO:0043933 | protein-containing complex organization | 23.2323 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.2323 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 23.2323 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 23.2323 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 23.2323 | 6 | no |
| GO:0002181 | cytoplasmic translation | 23.2323 | 5 | no |
| GO:0031399 | regulation of protein modification process | 23.2323 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.2222 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 22.2222 | 5 | no |
| GO:0023056 | positive regulation of signaling | 22.2222 | 4 | no |
| GO:0009894 | regulation of catabolic process | 22.2222 | 4 | no |
| GO:0033043 | regulation of organelle organization | 22.2222 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 21.2121 | 5 | yes |
| GO:0090304 | nucleic acid metabolic process | 21.2121 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.2121 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.2121 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.2121 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 21.2121 | 6 | no |
| GO:0051726 | regulation of cell cycle | 21.2121 | 4 | no |
| GO:0010608 | post-transcriptional regulation of gene expression | 20.2020 | 7 | yes |
| GO:0010628 | positive regulation of gene expression | 20.2020 | 7 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 20.2020 | 7 | no |
| GO:0043066 | negative regulation of apoptotic process | 20.2020 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 20.2020 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.2020 | 6 | no |
| GO:0008104 | protein localization | 20.2020 | 4 | no |
| GO:0051049 | regulation of transport | 20.2020 | 4 | no |
| GO:0006417 | regulation of translation | 19.1919 | 6 | yes |
| GO:0045727 | positive regulation of translation | 11.1111 | 7 | yes |
| GO:0022618 | protein-RNA complex assembly | 9.0909 | 6 | yes |
| GO:0071826 | protein-RNA complex organization | 9.0909 | 5 | yes |
| GO:0051099 | positive regulation of binding | 6.0606 | 4 | yes |
| GO:0001732 | formation of cytoplasmic translation initiation complex | 4.0404 | 7 | yes |
| GO:1902415 | regulation of mRNA binding | 4.0404 | 5 | yes |
| GO:1902416 | positive regulation of mRNA binding | 4.0404 | 6 | yes |
| GO:1905214 | regulation of RNA binding | 4.0404 | 4 | yes |
| GO:1905216 | positive regulation of RNA binding | 4.0404 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| IF6_HUMAN | [view interactions] | Low throughput | no | yes |
| RS3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS26_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ALKB4_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3H_HUMAN | [view interactions] | Low throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3F_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3G_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3M_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3L_HUMAN | [view interactions] | Low throughput | no | yes |
| RS7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS13_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS17_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RSSA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RS27_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EIF3J_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3D_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3K_HUMAN | [view interactions] | Low throughput | no | yes |
| EIF3B_HUMAN | [view interactions] | Low throughput | no | yes |
| IF4G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IF2G_HUMAN | [view interactions] | High throughput | no | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| EMC9_HUMAN | [view interactions] | High throughput | no | no |
| ENY2_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| CND2_HUMAN | [view interactions] | High throughput | no | no |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM42_HUMAN | [view interactions] | High throughput | no | yes |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| SRP19_HUMAN | [view interactions] | High throughput | no | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| SRP72_HUMAN | [view interactions] | High throughput | no | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| MEN1_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| CD11A_HUMAN | [view interactions] | High throughput | no | yes |
| CD11B_HUMAN | [view interactions] | High throughput | no | yes |
| CSK23_HUMAN | [view interactions] | High throughput | no | no |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BDP1_HUMAN | [view interactions] | High throughput | no | no |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| BOREA_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX7C_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GEMI4_HUMAN | [view interactions] | High throughput | no | yes |
| GPN3_HUMAN | [view interactions] | High throughput | no | yes |
| LEO1_HUMAN | [view interactions] | High throughput | no | yes |
| MED22_HUMAN | [view interactions] | High throughput | no | no |
| MTBP_HUMAN | [view interactions] | High throughput | no | no |
| NOL8_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD4_HUMAN | [view interactions] | High throughput | no | yes |
| SPF30_HUMAN | [view interactions] | High throughput | no | no |
| SNPC1_HUMAN | [view interactions] | High throughput | no | no |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERCC6_HUMAN | [view interactions] | High throughput | no | no |
| RL8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2P_HUMAN | [view interactions] | High throughput | no | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| MRP1_HUMAN | [view interactions] | High throughput | no | no |
| ODPX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM16_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CPT1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT35_HUMAN | [view interactions] | High throughput | no | yes |
| RM15_HUMAN | [view interactions] | High throughput | no | yes |
| G45IP_HUMAN | [view interactions] | High throughput | no | yes |
| RM02_HUMAN | [view interactions] | High throughput | no | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NELFB_HUMAN | [view interactions] | High throughput | no | yes |
| EI2BG_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| MTAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2B_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD9_HUMAN | [view interactions] | High throughput | no | yes |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| PFD1_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| CDC27_HUMAN | [view interactions] | High throughput | no | yes |
| PTTG_HUMAN | [view interactions] | High throughput | no | yes |
| UBP20_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| UBP3_HUMAN | [view interactions] | High throughput | no | no |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| RSF1_HUMAN | [view interactions] | High throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPG1_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| RL10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3I_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPBL1_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4A1_HUMAN | [view interactions] | High throughput | no | no |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RSPH9_HUMAN | [view interactions] | High throughput | no | no |
| RED1_HUMAN | [view interactions] | High throughput | no | no |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF1_HUMAN | [view interactions] | High throughput | no | no |
| IF1AX_HUMAN | [view interactions] | High throughput | no | yes |
| HG2A_HUMAN | [view interactions] | High throughput | no | yes |
| DDX60_HUMAN | [view interactions] | High throughput | no | no |
| MB212_HUMAN | [view interactions] | High throughput | no | no |
| ZAP70_HUMAN | [view interactions] | High throughput | no | no |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| SF01_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| DMD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| AAGAB_HUMAN | [view interactions] | High throughput | no | yes |
| NUA4L_HUMAN | [view interactions] | High throughput | no | yes |
| ITSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| IF4E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPC2A_HUMAN | [view interactions] | High throughput | no | yes |
| DSCAM_HUMAN | [view interactions] | High throughput | no | yes |
| BTG3_HUMAN | [view interactions] | High throughput | no | yes |
| RON_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| TRADD_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| TACC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCBP3_HUMAN | [view interactions] | High throughput | no | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| TAD2A_HUMAN | [view interactions] | High throughput | no | no |
| CD4_HUMAN | [view interactions] | High throughput | no | no |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ICAM1_HUMAN | [view interactions] | High throughput | no | no |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAN_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| GPBP1_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS28_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| IF4A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
| 4EBP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 4ET_HUMAN | [view interactions] | High throughput | no | yes |
| 4EBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANGE1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP10_HUMAN | [view interactions] | High throughput | no | yes |
| KDF1_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRC2B_HUMAN | [view interactions] | High throughput | no | no |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| EIFCL_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| ATG13_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC2_HUMAN | [view interactions] | High throughput | no | yes |
| DRG1_HUMAN | [view interactions] | High throughput | no | yes |