UBP14_HUMAN
Evidence for PS localization
Functions
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in UBP14_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 43.2836 | 4 | no |
| GO:0017076 | purine nucleotide binding | 23.8806 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 23.8806 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.8806 | 4 | no |
| GO:0004175 | endopeptidase activity | 2.9851 | 4 | yes |
| GO:0004843 | cysteine-type deubiquitinase activity | 2.4876 | 5 | yes |
| GO:0008234 | cysteine-type peptidase activity | 2.4876 | 4 | yes |
| GO:0019783 | ubiquitin-like protein peptidase activity | 2.4876 | 4 | yes |
| GO:0101005 | deubiquitinase activity | 2.4876 | 5 | yes |
| GO:0004197 | cysteine-type endopeptidase activity | 1.9900 | 5 | yes |
| GO:0061135 | endopeptidase regulator activity | 1.9900 | 4 | yes |
| GO:0004866 | endopeptidase inhibitor activity | 1.4925 | 5 | yes |
| GO:0030414 | peptidase inhibitor activity | 1.4925 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in UBP14_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 47.2637 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 44.7761 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 41.2935 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 41.2935 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 37.8109 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 33.8308 | 4 | yes |
| GO:0010468 | regulation of gene expression | 32.3383 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 30.8458 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 30.8458 | 4 | no |
| GO:0006996 | organelle organization | 29.8507 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 28.8557 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 28.8557 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 27.8607 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.3632 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 27.3632 | 5 | no |
| GO:0022607 | cellular component assembly | 25.3731 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.3781 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 24.3781 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 23.3831 | 5 | no |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 21.8905 | 4 | no |
| GO:0008104 | protein localization | 21.3930 | 4 | no |
| GO:0010646 | regulation of cell communication | 21.3930 | 4 | no |
| GO:0007010 | cytoskeleton organization | 21.3930 | 5 | no |
| GO:0033043 | regulation of organelle organization | 20.3980 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 19.9005 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 18.9055 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 17.9104 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 17.9104 | 5 | yes |
| GO:0043412 | macromolecule modification | 16.4179 | 4 | yes |
| GO:0036211 | protein modification process | 15.9204 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 14.9254 | 4 | yes |
| GO:0080134 | regulation of response to stress | 14.4279 | 4 | yes |
| GO:0006508 | proteolysis | 13.4328 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 12.4378 | 6 | yes |
| GO:0009057 | macromolecule catabolic process | 12.4378 | 4 | yes |
| GO:0031329 | regulation of cellular catabolic process | 11.9403 | 5 | yes |
| GO:0044265 | cellular macromolecule catabolic process | 11.4428 | 4 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 10.9453 | 5 | yes |
| GO:0080135 | regulation of cellular response to stress | 10.9453 | 4 | yes |
| GO:0030162 | regulation of proteolysis | 10.9453 | 6 | yes |
| GO:0019941 | modification-dependent protein catabolic process | 10.4478 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 10.4478 | 5 | yes |
| GO:0048585 | negative regulation of response to stimulus | 8.9552 | 4 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 8.4577 | 5 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 8.4577 | 7 | yes |
| GO:0042176 | regulation of protein catabolic process | 7.9602 | 5 | yes |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 7.4627 | 7 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 6.4677 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 6.4677 | 4 | yes |
| GO:0061136 | regulation of proteasomal protein catabolic process | 5.9701 | 6 | yes |
| GO:0030163 | protein catabolic process | 5.9701 | 4 | yes |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 5.4726 | 6 | yes |
| GO:0009895 | negative regulation of catabolic process | 5.4726 | 5 | yes |
| GO:0010498 | proteasomal protein catabolic process | 5.4726 | 5 | yes |
| GO:0031330 | negative regulation of cellular catabolic process | 4.9751 | 6 | yes |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 4.4776 | 6 | yes |
| GO:0045861 | negative regulation of proteolysis | 4.4776 | 7 | yes |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 3.9801 | 7 | yes |
| GO:1903051 | negative regulation of proteolysis involved in protein catabolic process | 2.9851 | 8 | yes |
| GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process | 2.9851 | 7 | yes |
| GO:0050920 | regulation of chemotaxis | 2.9851 | 4 | yes |
| GO:0070646 | protein modification by small protein removal | 2.4876 | 5 | yes |
| GO:0016579 | protein deubiquitination | 2.4876 | 6 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 2.4876 | 6 | yes |
| GO:1901799 | negative regulation of proteasomal protein catabolic process | 1.9900 | 7 | yes |
| GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | 1.9900 | 8 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 1.4925 | 5 | yes |
| GO:0099537 | trans-synaptic signaling | 1.4925 | 4 | yes |
| GO:1905897 | regulation of response to endoplasmic reticulum stress | 1.4925 | 5 | yes |
| GO:0007268 | chemical synaptic transmission | 1.4925 | 6 | yes |
| GO:1903069 | regulation of ER-associated ubiquitin-dependent protein catabolic process | 0.9950 | 7 | yes |
| GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process | 0.9950 | 7 | yes |
| GO:1903573 | negative regulation of response to endoplasmic reticulum stress | 0.9950 | 5 | yes |
| GO:1904292 | regulation of ERAD pathway | 0.9950 | 6 | yes |
| GO:1904293 | negative regulation of ERAD pathway | 0.9950 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in UBP14_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 1.4925 | 3 | no |
| DOID:0050155 | sensory system disease | 1.4925 | 3 | no |
| DOID:0050563 | nonsyndromic deafness | 1.4925 | 5 | no |
| DOID:0050564 | autosomal dominant nonsyndromic deafness | 1.4925 | 6 | no |
| DOID:2742 | auditory system disease | 1.4925 | 4 | no |
| DOID:114 | heart disease | 1.4925 | 3 | no |
| DOID:12377 | spinal muscular atrophy | 0.9950 | 6 | no |
| DOID:1289 | neurodegenerative disease | 0.9950 | 4 | no |
| DOID:231 | motor neuron disease | 0.9950 | 5 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 0.9950 | 7 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 0.9950 | 6 | no |
| DOID:440 | neuromuscular disease | 0.9950 | 5 | no |
| DOID:574 | peripheral nervous system disease | 0.9950 | 3 | no |
| DOID:870 | neuropathy | 0.9950 | 4 | no |
| DOID:1247 | blood coagulation disease | 0.9950 | 3 | no |
| DOID:2218 | blood platelet disease | 0.9950 | 4 | no |
| DOID:0050700 | cardiomyopathy | 0.9950 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 0.9950 | 5 | no |
| DOID:0080000 | muscular disease | 0.9950 | 3 | no |
| DOID:423 | myopathy | 0.9950 | 5 | no |
| DOID:65 | connective tissue disease | 0.9950 | 3 | no |
| DOID:66 | muscle tissue disease | 0.9950 | 4 | no |
| DOID:9884 | muscular dystrophy | 0.9950 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PP2BA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRS8_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMD4_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CANB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ERN1_HUMAN | [view interactions] | Low throughput | no | yes |
| GBRA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CXCR4_HUMAN | [view interactions] | Low throughput | no | no |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| GABR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| AURKB_HUMAN | [view interactions] | Low throughput | no | yes |
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI11_HUMAN | [view interactions] | Low throughput | no | yes |
| PSA4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | Low throughput | no | yes |
| RN168_HUMAN | [view interactions] | Low throughput | no | no |
| BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
| TAB2_HUMAN | [view interactions] | Low throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DDX58_HUMAN | [view interactions] | Low throughput | no | yes |
| SFI1_HUMAN | [view interactions] | Low throughput | no | no |
| CCNB1_HUMAN | [view interactions] | Low throughput | no | no |
| SPAG5_HUMAN | [view interactions] | Low throughput | no | yes |
| BCL6_HUMAN | [view interactions] | Low throughput | no | no |
| ATF2_HUMAN | [view interactions] | Low throughput | no | yes |
| MDM2_HUMAN | [view interactions] | Low throughput | no | yes |
| VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| KIF15_HUMAN | [view interactions] | Low throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MACF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | Low throughput | no | yes |
| UBX2B_HUMAN | [view interactions] | Low throughput | no | no |
| SNR40_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCH2_HUMAN | [view interactions] | High throughput | no | no |
| HAT1_HUMAN | [view interactions] | High throughput | no | yes |
| TBAL3_HUMAN | [view interactions] | High throughput | no | no |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2V2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2B3_HUMAN | [view interactions] | High throughput | no | no |
| SRRM1_HUMAN | [view interactions] | High throughput | no | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| LRRF1_HUMAN | [view interactions] | High throughput | no | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| MRE11_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| NOL10_HUMAN | [view interactions] | High throughput | no | yes |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| GARS_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| IRS4_HUMAN | [view interactions] | High throughput | no | no |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGPD5_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSB5_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD5_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| H14_HUMAN | [view interactions] | High throughput | no | yes |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| H13_HUMAN | [view interactions] | High throughput | no | no |
| ADRM1_HUMAN | [view interactions] | High throughput | no | yes |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHNK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| PA2G4_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| H2B1O_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| NCF1_HUMAN | [view interactions] | High throughput | no | no |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARFG1_HUMAN | [view interactions] | High throughput | no | no |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HRG_HUMAN | [view interactions] | High throughput | no | no |
| HP1B3_HUMAN | [view interactions] | High throughput | no | yes |
| PRPS2_HUMAN | [view interactions] | High throughput | no | no |
| PGS1_HUMAN | [view interactions] | High throughput | no | no |
| GBG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGR_HUMAN | [view interactions] | High throughput | no | no |
| CCD92_HUMAN | [view interactions] | High throughput | no | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSIP1_HUMAN | [view interactions] | High throughput | no | yes |
| PACN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FANCC_HUMAN | [view interactions] | High throughput | no | yes |
| TOP1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOSX_HUMAN | [view interactions] | High throughput | no | yes |
| RAI14_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN2_HUMAN | [view interactions] | High throughput | no | no |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| FLNC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSA2_HUMAN | [view interactions] | High throughput | no | yes |
| AIMP1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| RALA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHP1_HUMAN | [view interactions] | High throughput | no | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| LC7L2_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NOG2_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NU160_HUMAN | [view interactions] | High throughput | no | no |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
| DIM1_HUMAN | [view interactions] | High throughput | no | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNC_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYDC_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| PELO_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| ITPA_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| SYMC_HUMAN | [view interactions] | High throughput | no | yes |
| INADL_HUMAN | [view interactions] | High throughput | no | no |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PALS1_HUMAN | [view interactions] | High throughput | no | no |
| RGPD4_HUMAN | [view interactions] | High throughput | no | no |
| RMXL2_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| ARC1B_HUMAN | [view interactions] | High throughput | no | no |
| ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGB2_HUMAN | [view interactions] | High throughput | no | yes |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM3_HUMAN | [view interactions] | High throughput | no | no |
| DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF7_HUMAN | [view interactions] | High throughput | no | yes |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| DSG2_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA7_HUMAN | [view interactions] | High throughput | no | yes |
| RT28_HUMAN | [view interactions] | High throughput | no | yes |
| PSA5_HUMAN | [view interactions] | High throughput | no | yes |
| UT14A_HUMAN | [view interactions] | High throughput | no | yes |
| PSB2_HUMAN | [view interactions] | High throughput | no | yes |
| TBL3_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNL3_HUMAN | [view interactions] | High throughput | no | yes |
| BAF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBP56_HUMAN | [view interactions] | High throughput | no | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GUAA_HUMAN | [view interactions] | High throughput | no | no |
| EFHD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB4_HUMAN | [view interactions] | High throughput | no | yes |
| SR140_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| EFHD1_HUMAN | [view interactions] | High throughput | no | no |
| RADX_HUMAN | [view interactions] | High throughput | no | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMHD1_HUMAN | [view interactions] | High throughput | no | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAAF1_HUMAN | [view interactions] | High throughput | no | yes |
| NUCKS_HUMAN | [view interactions] | High throughput | no | yes |
| PSB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC124_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRCH2_HUMAN | [view interactions] | High throughput | no | no |
| IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VRK1_HUMAN | [view interactions] | High throughput | no | yes |
| UHRF1_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC9_HUMAN | [view interactions] | High throughput | no | yes |
| TM10C_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZMYM3_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| FABD_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCD86_HUMAN | [view interactions] | High throughput | no | yes |
| E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YTHD2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2B_HUMAN | [view interactions] | High throughput | no | yes |
| HPRT_HUMAN | [view interactions] | High throughput | no | yes |
| SYRC_HUMAN | [view interactions] | High throughput | no | yes |
| NMT1_HUMAN | [view interactions] | High throughput | no | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP72_HUMAN | [view interactions] | High throughput | no | yes |
| IF2P_HUMAN | [view interactions] | High throughput | no | yes |
| WDR82_HUMAN | [view interactions] | High throughput | no | no |
| NISCH_HUMAN | [view interactions] | High throughput | no | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRHPR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHF14_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| CNOT1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| OBSCN_HUMAN | [view interactions] | High throughput | no | yes |
| PSB3_HUMAN | [view interactions] | High throughput | no | yes |
| PFD2_HUMAN | [view interactions] | High throughput | no | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNA11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| NACAM_HUMAN | [view interactions] | High throughput | no | no |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| PUR8_HUMAN | [view interactions] | High throughput | no | yes |
| TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGN4_HUMAN | [view interactions] | High throughput | no | no |
| RL36_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRP15_HUMAN | [view interactions] | High throughput | no | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDGR2_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| TB182_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2AZ_HUMAN | [view interactions] | High throughput | no | yes |
| CD123_HUMAN | [view interactions] | High throughput | no | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7E_HUMAN | [view interactions] | High throughput | no | yes |
| H12_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| NDKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HORN_HUMAN | [view interactions] | High throughput | no | no |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRAP_HUMAN | [view interactions] | High throughput | no | no |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ECHM_HUMAN | [view interactions] | High throughput | no | yes |
| RL12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XRCC5_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| H2AY_HUMAN | [view interactions] | High throughput | no | yes |
| RIF1_HUMAN | [view interactions] | High throughput | no | yes |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX3_HUMAN | [view interactions] | High throughput | no | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF3_HUMAN | [view interactions] | High throughput | no | yes |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| ROA0_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AICDA_HUMAN | [view interactions] | High throughput | no | no |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| SEML_HUMAN | [view interactions] | High throughput | no | yes |
| DDX17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBP21_HUMAN | [view interactions] | High throughput | no | no |
| RL24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP28_HUMAN | [view interactions] | High throughput | no | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UN45A_HUMAN | [view interactions] | High throughput | no | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR12_HUMAN | [view interactions] | High throughput | no | yes |
| PSB7_HUMAN | [view interactions] | High throughput | no | yes |
| VP37B_HUMAN | [view interactions] | High throughput | no | yes |
| RL11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR4_HUMAN | [view interactions] | High throughput | no | yes |
| RL17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNDP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSHB_HUMAN | [view interactions] | High throughput | no | no |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| POTEI_HUMAN | [view interactions] | High throughput | no | no |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARFP1_HUMAN | [view interactions] | High throughput | no | no |
| RL13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHMP7_HUMAN | [view interactions] | High throughput | no | yes |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PNCB_HUMAN | [view interactions] | High throughput | no | no |
| TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDRG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL34_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN181_HUMAN | [view interactions] | High throughput | no | no |
| RS23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXND5_HUMAN | [view interactions] | High throughput | no | yes |
| DDX21_HUMAN | [view interactions] | High throughput | no | yes |
| UBCP1_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2V1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL4_HUMAN | [view interactions] | High throughput | no | yes |
| SYFA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFD1_HUMAN | [view interactions] | High throughput | no | no |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFN2B_HUMAN | [view interactions] | High throughput | no | yes |
| IMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMF1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| MYH14_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX5_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RALY_HUMAN | [view interactions] | High throughput | no | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM1_HUMAN | [view interactions] | High throughput | no | yes |
| TMM33_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF4_HUMAN | [view interactions] | High throughput | no | yes |
| GTF2I_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| CMBL_HUMAN | [view interactions] | High throughput | no | no |
| IF2B1_HUMAN | [view interactions] | High throughput | no | no |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SVIL_HUMAN | [view interactions] | High throughput | no | yes |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SP16H_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| DEK_HUMAN | [view interactions] | High throughput | no | yes |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| SSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3F_HUMAN | [view interactions] | High throughput | no | yes |
| YBOX3_HUMAN | [view interactions] | High throughput | no | yes |
| PSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CING_HUMAN | [view interactions] | High throughput | no | no |
| C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSME4_HUMAN | [view interactions] | Computational | no | yes |
| UBP2_HUMAN | [view interactions] | Computational | no | yes |
| UBP13_HUMAN | [view interactions] | Computational | no | yes |
| RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UBP5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PSB11_HUMAN | [view interactions] | Computational | no | no |
| PSB10_HUMAN | [view interactions] | Computational | no | no |
| PSB9_HUMAN | [view interactions] | Computational | no | no |
| PSME3_HUMAN | [view interactions] | Computational | no | yes |
| PSMA8_HUMAN | [view interactions] | Computational | no | no |
| TGT_HUMAN | [view interactions] | Computational | no | no |
| UCHL3_HUMAN | [view interactions] | Computational | no | yes |
| UBP6_HUMAN | [view interactions] | Computational | no | no |
| PSB8_HUMAN | [view interactions] | Computational | no | yes |
| UBE3C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |