Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SH3L2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SH3L2_HUMAN
GO:0000166 nucleotide binding 33.3333 4 no
GO:0017076 purine nucleotide binding 33.3333 5 no
GO:0030554 adenyl nucleotide binding 33.3333 6 no
GO:0032555 purine ribonucleotide binding 33.3333 4 no
GO:0032559 adenyl ribonucleotide binding 33.3333 5 no
GO:0043168 anion binding 33.3333 4 no
GO:0045296 cadherin binding 25.0000 4 no
GO:0005524 ATP binding 25.0000 5 no
GO:0035639 purine ribonucleoside triphosphate binding 25.0000 4 no
GO:0019900 kinase binding 25.0000 4 no
GO:0019901 protein kinase binding 25.0000 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SH3L2_HUMAN
GO:0051246 regulation of protein metabolic process 58.3333 5 no
GO:0060255 regulation of macromolecule metabolic process 58.3333 4 no
GO:0080090 regulation of primary metabolic process 58.3333 4 no
GO:0048523 negative regulation of cellular process 58.3333 4 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0048522 positive regulation of cellular process 50.0000 4 no
GO:0009893 positive regulation of metabolic process 41.6667 4 no
GO:0009966 regulation of signal transduction 41.6667 4 no
GO:0010604 positive regulation of macromolecule metabolic process 41.6667 5 no
GO:0010605 negative regulation of macromolecule metabolic process 41.6667 5 no
GO:0010646 regulation of cell communication 41.6667 4 no
GO:0019220 regulation of phosphate metabolic process 41.6667 6 no
GO:0031325 positive regulation of cellular metabolic process 41.6667 5 no
GO:0031399 regulation of protein modification process 41.6667 6 no
GO:0042325 regulation of phosphorylation 41.6667 7 no
GO:0051174 regulation of phosphorus metabolic process 41.6667 5 no
GO:0051248 negative regulation of protein metabolic process 41.6667 6 no
GO:0006996 organelle organization 41.6667 4 no
GO:0007010 cytoskeleton organization 41.6667 5 no
GO:0022607 cellular component assembly 41.6667 4 no
GO:0051128 regulation of cellular component organization 41.6667 4 no
GO:0001932 regulation of protein phosphorylation 41.6667 7 no
GO:0009892 negative regulation of metabolic process 41.6667 4 no
GO:0010468 regulation of gene expression 33.3333 6 no
GO:0010556 regulation of macromolecule biosynthetic process 33.3333 5 no
GO:0030162 regulation of proteolysis 33.3333 6 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0031326 regulation of cellular biosynthetic process 33.3333 5 no
GO:0042981 regulation of apoptotic process 33.3333 5 no
GO:0043067 regulation of programmed cell death 33.3333 4 no
GO:0043085 positive regulation of catalytic activity 33.3333 4 no
GO:0043549 regulation of kinase activity 33.3333 5 no
GO:0043933 protein-containing complex organization 33.3333 4 no
GO:0045859 regulation of protein kinase activity 33.3333 6 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0051338 regulation of transferase activity 33.3333 4 no
GO:0071310 cellular response to organic substance 33.3333 4 no
GO:1901701 cellular response to oxygen-containing compound 33.3333 4 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 no
GO:0009889 regulation of biosynthetic process 33.3333 4 no
GO:0009968 negative regulation of signal transduction 25.0000 5 no
GO:0010243 response to organonitrogen compound 25.0000 4 no
GO:0010562 positive regulation of phosphorus metabolic process 25.0000 6 no
GO:0010563 negative regulation of phosphorus metabolic process 25.0000 6 no
GO:0010648 negative regulation of cell communication 25.0000 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0023057 negative regulation of signaling 25.0000 4 no
GO:0031400 negative regulation of protein modification process 25.0000 7 no
GO:0031401 positive regulation of protein modification process 25.0000 7 no
GO:0034762 regulation of transmembrane transport 25.0000 4 no
GO:0042127 regulation of cell population proliferation 25.0000 4 no
GO:0042326 negative regulation of phosphorylation 25.0000 8 no
GO:0042327 positive regulation of phosphorylation 25.0000 8 no
GO:0043066 negative regulation of apoptotic process 25.0000 6 no
GO:0043069 negative regulation of programmed cell death 25.0000 5 no
GO:0045936 negative regulation of phosphate metabolic process 25.0000 7 no
GO:0045937 positive regulation of phosphate metabolic process 25.0000 7 no
GO:0048585 negative regulation of response to stimulus 25.0000 4 no
GO:0051049 regulation of transport 25.0000 4 no
GO:0051252 regulation of RNA metabolic process 25.0000 5 no
GO:0065003 protein-containing complex assembly 25.0000 5 no
GO:0071417 cellular response to organonitrogen compound 25.0000 4 no
GO:1901699 cellular response to nitrogen compound 25.0000 4 no
GO:2001141 regulation of RNA biosynthetic process 25.0000 6 no
GO:0008104 protein localization 25.0000 4 no
GO:0036211 protein modification process 25.0000 4 no
GO:0043086 negative regulation of catalytic activity 25.0000 4 no
GO:0043408 regulation of MAPK cascade 25.0000 6 no
GO:0043412 macromolecule modification 25.0000 4 no
GO:0045595 regulation of cell differentiation 25.0000 4 no
GO:0030030 cell projection organization 25.0000 4 no
GO:0031344 regulation of cell projection organization 25.0000 5 no
GO:0051129 negative regulation of cellular component organization 25.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.0000 6 no
GO:0001933 negative regulation of protein phosphorylation 25.0000 8 no
GO:0001934 positive regulation of protein phosphorylation 25.0000 8 no
GO:0006355 regulation of DNA-templated transcription 25.0000 7 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
IQCB1_HUMAN [view interactions] High throughput no no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
MB212_HUMAN [view interactions] High throughput no no
DAPK1_HUMAN [view entry] [view interactions] High throughput yes yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
BMI1_HUMAN [view interactions] High throughput no yes
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
PCNA_HUMAN [view interactions] High throughput no no
PAN2_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
BCAR1_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
PLK4_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
FOXA1_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
VIGLN_HUMAN [view entry] [view interactions] High throughput yes yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
UB2D1_HUMAN [view interactions] High throughput no yes