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PP2BA_HUMAN

Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals (PubMed, PubMed, PubMed, PubMed). Many of the substrates contain a PxIxIT motif and/or a LxVP motif (PubMed, PubMed, PubMed, PubMed, PubMed). In response to increased Ca(2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed). In response to increased Ca(2+) levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (PubMed). Dephosphorylates heat shock protein HSPB1 . Dephosphorylates and activates transcription factor NFATC1 (PubMed). In response to increased Ca(2+) levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed). Dephosphorylates and inactivates transcription factor ELK1 (PubMed). Dephosphorylates DARPP32 (PubMed). May dephosphorylate CRTC2 at Ser-171 resulting in CRTC2 dissociation from 14-3-3 proteins (PubMed). Dephosphorylates transcription factor TFEB at Ser-211 following Coxsackievirus B3 infection, promoting nuclear translocation (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in PP2BA_HUMAN
GO:0043169 cation binding 38.7500 4 yes
GO:0046872 metal ion binding 37.5000 5 yes
GO:0019900 kinase binding 31.2500 4 no
GO:0019901 protein kinase binding 25.0000 5 no
GO:0043168 anion binding 25.0000 4 no
GO:0005509 calcium ion binding 12.5000 6 yes
GO:0042578 phosphoric ester hydrolase activity 8.7500 4 yes
GO:0016791 phosphatase activity 7.5000 5 yes
GO:0004722 protein serine/threonine phosphatase activity 6.2500 4 yes
GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 5.0000 5 yes
GO:0017018 myosin phosphatase activity 5.0000 5 yes
GO:0033192 calmodulin-dependent protein phosphatase activity 3.7500 6 yes
GO:0051117 ATPase binding 3.7500 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PP2BA_HUMAN
GO:0048522 positive regulation of cellular process 66.2500 4 yes
GO:0010646 regulation of cell communication 56.2500 4 yes
GO:0060255 regulation of macromolecule metabolic process 56.2500 4 yes
GO:0031323 regulation of cellular metabolic process 55.0000 4 yes
GO:0009966 regulation of signal transduction 53.7500 4 yes
GO:0048523 negative regulation of cellular process 53.7500 4 yes
GO:0080090 regulation of primary metabolic process 52.5000 4 yes
GO:0009893 positive regulation of metabolic process 47.5000 4 yes
GO:0051128 regulation of cellular component organization 47.5000 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 45.0000 5 yes
GO:0009889 regulation of biosynthetic process 42.5000 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 41.2500 5 yes
GO:0031325 positive regulation of cellular metabolic process 41.2500 5 yes
GO:0031326 regulation of cellular biosynthetic process 41.2500 5 yes
GO:0010468 regulation of gene expression 38.7500 6 yes
GO:0048584 positive regulation of response to stimulus 38.7500 4 yes
GO:0022607 cellular component assembly 37.5000 4 no
GO:0051049 regulation of transport 37.5000 4 yes
GO:1902531 regulation of intracellular signal transduction 36.2500 5 yes
GO:0051246 regulation of protein metabolic process 36.2500 5 no
GO:0010647 positive regulation of cell communication 36.2500 5 yes
GO:0023056 positive regulation of signaling 36.2500 4 yes
GO:0009892 negative regulation of metabolic process 33.7500 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 33.7500 5 yes
GO:0006996 organelle organization 32.5000 4 no
GO:0031324 negative regulation of cellular metabolic process 32.5000 5 yes
GO:0048585 negative regulation of response to stimulus 32.5000 4 yes
GO:0031399 regulation of protein modification process 31.2500 6 no
GO:0009967 positive regulation of signal transduction 31.2500 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 31.2500 5 yes
GO:0043412 macromolecule modification 31.2500 4 yes
GO:0099177 regulation of trans-synaptic signaling 30.0000 4 yes
GO:0019220 regulation of phosphate metabolic process 30.0000 6 no
GO:0051174 regulation of phosphorus metabolic process 30.0000 5 no
GO:0023057 negative regulation of signaling 30.0000 4 yes
GO:0034762 regulation of transmembrane transport 30.0000 4 yes
GO:0036211 protein modification process 30.0000 4 yes
GO:0050804 modulation of chemical synaptic transmission 30.0000 5 yes
GO:0009891 positive regulation of biosynthetic process 28.7500 5 yes
GO:0051247 positive regulation of protein metabolic process 28.7500 6 no
GO:0010648 negative regulation of cell communication 28.7500 5 yes
GO:0051130 positive regulation of cellular component organization 28.7500 5 yes
GO:0051252 regulation of RNA metabolic process 28.7500 5 yes
GO:0006796 phosphate-containing compound metabolic process 27.5000 4 yes
GO:0008104 protein localization 27.5000 4 yes
GO:0009968 negative regulation of signal transduction 27.5000 5 yes
GO:0043933 protein-containing complex organization 27.5000 4 no
GO:0031328 positive regulation of cellular biosynthetic process 27.5000 6 yes
GO:0043269 regulation of monoatomic ion transport 27.5000 5 yes
GO:0071310 cellular response to organic substance 26.2500 4 yes
GO:0006355 regulation of DNA-templated transcription 26.2500 7 yes
GO:2001141 regulation of RNA biosynthetic process 26.2500 6 yes
GO:0043085 positive regulation of catalytic activity 26.2500 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 26.2500 6 yes
GO:0051050 positive regulation of transport 26.2500 4 yes
GO:0033043 regulation of organelle organization 25.0000 5 no
GO:0034765 regulation of monoatomic ion transmembrane transport 25.0000 5 yes
GO:0060341 regulation of cellular localization 25.0000 4 yes
GO:0141124 intracellular signaling cassette 23.7500 4 yes
GO:0031401 positive regulation of protein modification process 23.7500 7 no
GO:0042325 regulation of phosphorylation 23.7500 7 no
GO:0009890 negative regulation of biosynthetic process 23.7500 5 yes
GO:0009894 regulation of catabolic process 23.7500 4 no
GO:0010243 response to organonitrogen compound 23.7500 4 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 23.7500 6 yes
GO:0010959 regulation of metal ion transport 23.7500 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 23.7500 6 yes
GO:0032880 regulation of protein localization 23.7500 5 yes
GO:1904062 regulation of monoatomic cation transmembrane transport 22.5000 6 yes
GO:0043067 regulation of programmed cell death 22.5000 4 no
GO:0051338 regulation of transferase activity 22.5000 4 no
GO:0031344 regulation of cell projection organization 22.5000 5 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 22.5000 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.2500 6 yes
GO:1901701 cellular response to oxygen-containing compound 21.2500 4 yes
GO:0001932 regulation of protein phosphorylation 21.2500 7 no
GO:0042981 regulation of apoptotic process 21.2500 5 no
GO:0044087 regulation of cellular component biogenesis 21.2500 4 no
GO:0051248 negative regulation of protein metabolic process 21.2500 6 no
GO:0043270 positive regulation of monoatomic ion transport 20.0000 5 yes
GO:0051129 negative regulation of cellular component organization 20.0000 5 yes
GO:0051240 positive regulation of multicellular organismal process 20.0000 4 yes
GO:0051924 regulation of calcium ion transport 20.0000 7 yes
GO:0080134 regulation of response to stress 18.7500 4 yes
GO:1902533 positive regulation of intracellular signal transduction 18.7500 6 yes
GO:1902680 positive regulation of RNA biosynthetic process 18.7500 7 yes
GO:1903169 regulation of calcium ion transmembrane transport 18.7500 7 yes
GO:0006357 regulation of transcription by RNA polymerase II 18.7500 8 yes
GO:0030030 cell projection organization 18.7500 4 yes
GO:0033365 protein localization to organelle 18.7500 5 yes
GO:0044057 regulation of system process 18.7500 4 yes
GO:0045893 positive regulation of DNA-templated transcription 18.7500 8 yes
GO:0051094 positive regulation of developmental process 18.7500 4 yes
GO:0051254 positive regulation of RNA metabolic process 18.7500 6 yes
GO:0071702 organic substance transport 17.5000 4 yes
GO:0010038 response to metal ion 17.5000 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 17.5000 4 yes
GO:0034764 positive regulation of transmembrane transport 17.5000 5 yes
GO:0042127 regulation of cell population proliferation 17.5000 4 yes
GO:0051051 negative regulation of transport 17.5000 4 yes
GO:0071705 nitrogen compound transport 16.2500 4 yes
GO:0006811 monoatomic ion transport 16.2500 4 yes
GO:0010629 negative regulation of gene expression 16.2500 7 yes
GO:0034767 positive regulation of monoatomic ion transmembrane transport 16.2500 6 yes
GO:0045595 regulation of cell differentiation 16.2500 4 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 16.2500 9 yes
GO:2000026 regulation of multicellular organismal development 15.0000 4 yes
GO:0050848 regulation of calcium-mediated signaling 15.0000 6 yes
GO:0051241 negative regulation of multicellular organismal process 15.0000 4 yes
GO:0051928 positive regulation of calcium ion transport 15.0000 6 yes
GO:1904064 positive regulation of cation transmembrane transport 13.7500 7 yes
GO:1904427 positive regulation of calcium ion transmembrane transport 13.7500 7 yes
GO:0010628 positive regulation of gene expression 13.7500 7 yes
GO:0010975 regulation of neuron projection development 13.7500 7 yes
GO:0030155 regulation of cell adhesion 13.7500 4 yes
GO:0051093 negative regulation of developmental process 13.7500 4 yes
GO:0060284 regulation of cell development 13.7500 5 yes
GO:0070201 regulation of establishment of protein localization 13.7500 6 yes
GO:0015031 protein transport 12.5000 4 yes
GO:0060627 regulation of vesicle-mediated transport 12.5000 4 yes
GO:0090257 regulation of muscle system process 11.2500 5 yes
GO:0002684 positive regulation of immune system process 11.2500 4 yes
GO:0006812 monoatomic cation transport 11.2500 5 yes
GO:0008284 positive regulation of cell population proliferation 11.2500 5 yes
GO:0019722 calcium-mediated signaling 11.2500 5 yes
GO:0030001 metal ion transport 11.2500 6 yes
GO:0030100 regulation of endocytosis 11.2500 5 yes
GO:0034763 negative regulation of transmembrane transport 11.2500 5 yes
GO:0045597 positive regulation of cell differentiation 11.2500 5 yes
GO:0051046 regulation of secretion 11.2500 5 yes
GO:0051960 regulation of nervous system development 11.2500 5 yes
GO:0060078 regulation of postsynaptic membrane potential 11.2500 4 yes
GO:1903530 regulation of secretion by cell 10.0000 4 yes
GO:1903828 negative regulation of protein localization 10.0000 5 yes
GO:0006886 intracellular protein transport 10.0000 4 yes
GO:2000145 regulation of cell motility 10.0000 4 yes
GO:0030334 regulation of cell migration 10.0000 5 yes
GO:0045785 positive regulation of cell adhesion 10.0000 5 yes
GO:0050767 regulation of neurogenesis 10.0000 6 yes
GO:0051047 positive regulation of secretion 10.0000 5 yes
GO:0051223 regulation of protein transport 10.0000 5 yes
GO:0070884 regulation of calcineurin-NFAT signaling cascade 8.7500 8 yes
GO:0072594 establishment of protein localization to organelle 8.7500 4 yes
GO:0090279 regulation of calcium ion import 8.7500 8 yes
GO:0106056 regulation of calcineurin-mediated signaling 8.7500 7 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 8.7500 4 yes
GO:1903170 negative regulation of calcium ion transmembrane transport 8.7500 7 yes
GO:0002694 regulation of leukocyte activation 8.7500 4 yes
GO:1904063 negative regulation of cation transmembrane transport 8.7500 7 yes
GO:0006816 calcium ion transport 8.7500 7 yes
GO:0031345 negative regulation of cell projection organization 8.7500 6 yes
GO:0034766 negative regulation of monoatomic ion transmembrane transport 8.7500 6 yes
GO:0043271 negative regulation of monoatomic ion transport 8.7500 5 yes
GO:0050865 regulation of cell activation 8.7500 4 yes
GO:0051926 negative regulation of calcium ion transport 8.7500 6 yes
GO:0060079 excitatory postsynaptic potential 8.7500 5 yes
GO:1905664 regulation of calcium ion import across plasma membrane 7.5000 8 yes
GO:0010720 positive regulation of cell development 7.5000 6 yes
GO:0030855 epithelial cell differentiation 7.5000 4 yes
GO:0034504 protein localization to nucleus 7.5000 6 yes
GO:0044772 mitotic cell cycle phase transition 7.5000 4 yes
GO:0045596 negative regulation of cell differentiation 7.5000 5 yes
GO:0048812 neuron projection morphogenesis 7.5000 5 yes
GO:0050708 regulation of protein secretion 7.5000 5 yes
GO:0051249 regulation of lymphocyte activation 7.5000 5 yes
GO:0051592 response to calcium ion 7.5000 5 yes
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 6.2500 9 yes
GO:0090087 regulation of peptide transport 6.2500 5 yes
GO:0090276 regulation of peptide hormone secretion 6.2500 5 yes
GO:0090280 positive regulation of calcium ion import 6.2500 7 yes
GO:0106058 positive regulation of calcineurin-mediated signaling 6.2500 8 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 6.2500 6 yes
GO:0002696 positive regulation of leukocyte activation 6.2500 5 yes
GO:0002791 regulation of peptide secretion 6.2500 6 yes
GO:0006606 protein import into nucleus 6.2500 5 yes
GO:1905665 positive regulation of calcium ion import across plasma membrane 6.2500 8 yes
GO:0006913 nucleocytoplasmic transport 6.2500 5 yes
GO:2000147 positive regulation of cell motility 6.2500 5 yes
GO:0008277 regulation of G protein-coupled receptor signaling pathway 6.2500 5 yes
GO:0010721 negative regulation of cell development 6.2500 6 yes
GO:0016311 dephosphorylation 6.2500 5 yes
GO:0022407 regulation of cell-cell adhesion 6.2500 5 yes
GO:0030335 positive regulation of cell migration 6.2500 6 yes
GO:0040017 positive regulation of locomotion 6.2500 4 yes
GO:0042110 T cell activation 6.2500 4 yes
GO:0046883 regulation of hormone secretion 6.2500 4 yes
GO:0050796 regulation of insulin secretion 6.2500 6 yes
GO:0050850 positive regulation of calcium-mediated signaling 6.2500 7 yes
GO:0050863 regulation of T cell activation 6.2500 6 yes
GO:0050867 positive regulation of cell activation 6.2500 5 yes
GO:0051169 nuclear transport 6.2500 4 yes
GO:0051170 import into nucleus 6.2500 6 yes
GO:0051251 positive regulation of lymphocyte activation 6.2500 6 yes
GO:0055001 muscle cell development 6.2500 4 yes
GO:0090281 negative regulation of calcium ion import 5.0000 7 yes
GO:0097720 calcineurin-mediated signaling 5.0000 6 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 5.0000 7 yes
GO:1903531 negative regulation of secretion by cell 5.0000 5 yes
GO:1904950 negative regulation of establishment of protein localization 5.0000 6 yes
GO:0006470 protein dephosphorylation 5.0000 5 yes
GO:1905949 negative regulation of calcium ion import across plasma membrane 5.0000 8 yes
GO:0014904 myotube cell development 5.0000 5 yes
GO:0022409 positive regulation of cell-cell adhesion 5.0000 6 yes
GO:0033173 calcineurin-NFAT signaling cascade 5.0000 7 yes
GO:0042593 glucose homeostasis 5.0000 4 yes
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 5.0000 6 yes
GO:0048741 skeletal muscle fiber development 5.0000 6 yes
GO:0050768 negative regulation of neurogenesis 5.0000 6 yes
GO:0050773 regulation of dendrite development 5.0000 4 yes
GO:0050870 positive regulation of T cell activation 5.0000 7 yes
GO:0051048 negative regulation of secretion 5.0000 5 yes
GO:0051961 negative regulation of nervous system development 5.0000 5 yes
GO:0070663 regulation of leukocyte proliferation 3.7500 5 yes
GO:0071322 cellular response to carbohydrate stimulus 3.7500 5 yes
GO:0071326 cellular response to monosaccharide stimulus 3.7500 6 yes
GO:0071331 cellular response to hexose stimulus 3.7500 7 yes
GO:0071333 cellular response to glucose stimulus 3.7500 5 yes
GO:0090278 negative regulation of peptide hormone secretion 3.7500 6 yes
GO:0099170 postsynaptic modulation of chemical synaptic transmission 3.7500 6 yes
GO:1902105 regulation of leukocyte differentiation 3.7500 5 yes
GO:0001678 intracellular glucose homeostasis 3.7500 4 yes
GO:0001975 response to amphetamine 3.7500 6 yes
GO:1903706 regulation of hemopoiesis 3.7500 4 yes
GO:0002792 negative regulation of peptide secretion 3.7500 6 yes
GO:0009743 response to carbohydrate 3.7500 4 yes
GO:0009746 response to hexose 3.7500 6 yes
GO:0009749 response to glucose 3.7500 7 yes
GO:0010611 regulation of cardiac muscle hypertrophy 3.7500 5 yes
GO:0010613 positive regulation of cardiac muscle hypertrophy 3.7500 6 yes
GO:0014075 response to amine 3.7500 5 yes
GO:0014742 positive regulation of muscle hypertrophy 3.7500 5 yes
GO:0014743 regulation of muscle hypertrophy 3.7500 6 yes
GO:0032944 regulation of mononuclear cell proliferation 3.7500 6 yes
GO:0034284 response to monosaccharide 3.7500 5 yes
GO:0042060 wound healing 3.7500 4 yes
GO:0042129 regulation of T cell proliferation 3.7500 7 yes
GO:0043502 regulation of muscle adaptation 3.7500 4 yes
GO:0045667 regulation of osteoblast differentiation 3.7500 5 yes
GO:0045807 positive regulation of endocytosis 3.7500 5 yes
GO:0046006 regulation of activated T cell proliferation 3.7500 8 yes
GO:0046676 negative regulation of insulin secretion 3.7500 7 yes
GO:0046888 negative regulation of hormone secretion 3.7500 5 yes
GO:0048814 regulation of dendrite morphogenesis 3.7500 5 yes
GO:0050670 regulation of lymphocyte proliferation 3.7500 6 yes
GO:0050709 negative regulation of protein secretion 3.7500 6 yes
GO:0051224 negative regulation of protein transport 3.7500 5 yes
GO:0070665 positive regulation of leukocyte proliferation 2.5000 6 yes
GO:0090183 regulation of kidney development 2.5000 4 yes
GO:0090184 positive regulation of kidney development 2.5000 5 yes
GO:0090192 regulation of glomerulus development 2.5000 5 yes
GO:0090193 positive regulation of glomerulus development 2.5000 6 yes
GO:0097205 renal filtration 2.5000 4 yes
GO:0110061 regulation of angiotensin-activated signaling pathway 2.5000 6 yes
GO:0110062 negative regulation of angiotensin-activated signaling pathway 2.5000 7 yes
GO:1902107 positive regulation of leukocyte differentiation 2.5000 6 yes
GO:0000082 G1/S transition of mitotic cell cycle 2.5000 5 yes
GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 2.5000 5 yes
GO:1903244 positive regulation of cardiac muscle hypertrophy in response to stress 2.5000 6 yes
GO:0002761 regulation of myeloid leukocyte differentiation 2.5000 6 yes
GO:1903708 positive regulation of hemopoiesis 2.5000 5 yes
GO:0002763 positive regulation of myeloid leukocyte differentiation 2.5000 7 yes
GO:0003300 cardiac muscle hypertrophy 2.5000 6 yes
GO:1905203 regulation of connective tissue replacement 2.5000 5 yes
GO:1905205 positive regulation of connective tissue replacement 2.5000 6 yes
GO:0008544 epidermis development 2.5000 4 yes
GO:0009913 epidermal cell differentiation 2.5000 5 yes
GO:0010612 regulation of cardiac muscle adaptation 2.5000 5 yes
GO:0010615 positive regulation of cardiac muscle adaptation 2.5000 6 yes
GO:0014733 regulation of skeletal muscle adaptation 2.5000 5 yes
GO:0014744 positive regulation of muscle adaptation 2.5000 5 yes
GO:0014883 transition between fast and slow fiber 2.5000 6 yes
GO:0014887 cardiac muscle adaptation 2.5000 4 yes
GO:0014896 muscle hypertrophy 2.5000 4 yes
GO:0014897 striated muscle hypertrophy 2.5000 5 yes
GO:0014898 cardiac muscle hypertrophy in response to stress 2.5000 4 yes
GO:0030216 keratinocyte differentiation 2.5000 6 yes
GO:0032946 positive regulation of mononuclear cell proliferation 2.5000 7 yes
GO:0034103 regulation of tissue remodeling 2.5000 4 yes
GO:0034105 positive regulation of tissue remodeling 2.5000 5 yes
GO:0042102 positive regulation of T cell proliferation 2.5000 8 yes
GO:0042104 positive regulation of activated T cell proliferation 2.5000 9 yes
GO:0043403 skeletal muscle tissue regeneration 2.5000 4 yes
GO:0044058 regulation of digestive system process 2.5000 5 yes
GO:0044843 cell cycle G1/S phase transition 2.5000 4 yes
GO:0045637 regulation of myeloid cell differentiation 2.5000 5 yes
GO:0045639 positive regulation of myeloid cell differentiation 2.5000 6 yes
GO:0045669 positive regulation of osteoblast differentiation 2.5000 6 yes
GO:0045670 regulation of osteoclast differentiation 2.5000 7 yes
GO:0045672 positive regulation of osteoclast differentiation 2.5000 8 yes
GO:0046877 regulation of saliva secretion 2.5000 4 yes
GO:0046878 positive regulation of saliva secretion 2.5000 5 yes
GO:0048813 dendrite morphogenesis 2.5000 6 yes
GO:0050671 positive regulation of lymphocyte proliferation 2.5000 7 yes
GO:0050774 negative regulation of dendrite morphogenesis 2.5000 6 yes
GO:0060456 positive regulation of digestive system process 2.5000 5 yes
GO:0061006 regulation of cell proliferation involved in kidney morphogenesis 2.5000 5 yes
GO:0070262 peptidyl-serine dephosphorylation 2.5000 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
UBP14_HUMAN [view entry] [view interactions] Low throughput yes yes
CRTC2_HUMAN [view interactions] Low throughput no yes
AKAP5_HUMAN [view entry] [view interactions] Low throughput yes yes
CAC1C_HUMAN [view entry] [view interactions] Low throughput yes no
CANB1_HUMAN [view entry] [view interactions] Low throughput yes yes
CCG8_HUMAN [view entry] [view interactions] Low throughput yes no
NFAC1_HUMAN [view interactions] Low throughput no no
NFAC2_HUMAN [view interactions] Low throughput no yes
JUN_HUMAN [view interactions] Low throughput no yes
UTRN_HUMAN [view entry] [view interactions] Low throughput yes yes
SYNJ1_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNJ8_HUMAN [view interactions] Low throughput no yes
LASP1_HUMAN [view entry] [view interactions] Low throughput yes yes
RCAN1_HUMAN [view interactions] Low throughput no yes
CABIN_HUMAN [view interactions] Low throughput no yes
FBX32_HUMAN [view interactions] Low throughput no no
PSA6_HUMAN [view interactions] Low throughput no yes
MARH7_HUMAN [view interactions] Low throughput no yes
TRI72_HUMAN [view interactions] Low throughput no no
BCL2_HUMAN [view interactions] Low throughput no no
MYOZ2_HUMAN [view interactions] Low throughput no no
MYOZ1_HUMAN [view interactions] Low throughput no no
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
PHLP2_HUMAN [view interactions] Low throughput no yes
PTEN_HUMAN [view entry] [view interactions] Low throughput yes yes
PDE4D_HUMAN [view entry] [view interactions] Low throughput yes yes
TRAF3_HUMAN [view entry] [view interactions] Low throughput yes yes
GBRG2_HUMAN [view entry] [view interactions] Low throughput yes no
GBRB2_HUMAN [view entry] [view interactions] Low throughput yes no
GBRA1_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
RCAN2_HUMAN [view interactions] Low throughput no yes
SC6A4_HUMAN [view entry] [view interactions] Low throughput yes no
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
FKBP5_HUMAN [view interactions] Low throughput no yes
CSEN_HUMAN [view interactions] Low throughput no no
DYN1_HUMAN [view entry] [view interactions] Low throughput yes yes
KLHL3_HUMAN [view interactions] Low throughput no no
PPIA_HUMAN [view entry] [view interactions] Low throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] Low throughput yes no
PP2BA_HUMAN [view entry] [view interactions] Low throughput yes yes
SL9A1_HUMAN [view interactions] Low throughput no no
ABL1_HUMAN [view entry] [view interactions] High throughput yes yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
IRF2_HUMAN [view interactions] High throughput no yes
SH3K1_HUMAN [view entry] [view interactions] High throughput yes yes
ELK1_HUMAN [view interactions] High throughput no yes
GRB10_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
NMDZ1_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
MTR1B_HUMAN [view interactions] High throughput no yes
M3K12_HUMAN [view entry] [view interactions] High throughput yes yes
CDK1_HUMAN [view interactions] High throughput no no
SPTCS_HUMAN [view interactions] High throughput no yes
NMDE2_HUMAN [view entry] [view interactions] High throughput yes no
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
NEUL1_HUMAN [view entry] [view interactions] High throughput yes yes
HOME1_HUMAN [view entry] [view interactions] High throughput yes yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP1_HUMAN [view entry] [view interactions] High throughput yes no
AGAP2_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
MET_HUMAN [view interactions] High throughput no yes
CP074_HUMAN [view interactions] High throughput no no
LMTK1_HUMAN [view interactions] High throughput no yes
ERBB3_HUMAN [view interactions] High throughput no yes
FGFR4_HUMAN [view interactions] High throughput no no
RYK_HUMAN [view entry] [view interactions] High throughput yes no
PTK7_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
BTG3_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
RXRB_HUMAN [view interactions] High throughput no yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
SWAP1_HUMAN [view interactions] High throughput no no
AMPH_HUMAN [view entry] [view interactions] High throughput yes yes
U119A_HUMAN [view interactions] High throughput no no
TENS4_HUMAN [view interactions] High throughput no no
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
IP3KB_HUMAN [view interactions] High throughput no no
PLAC8_HUMAN [view interactions] High throughput no no
ARMT1_HUMAN [view interactions] High throughput no yes
F167A_HUMAN [view interactions] High throughput no yes
SHAN2_HUMAN [view entry] [view interactions] High throughput yes yes
CANB2_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
MK07_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CEP76_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
PBIR1_HUMAN [view interactions] High throughput no yes
RASF2_HUMAN [view interactions] High throughput no yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
RCAN3_HUMAN [view interactions] High throughput no no
NFAC4_HUMAN [view interactions] High throughput no yes
SIK3_HUMAN [view interactions] High throughput no yes
LNX1_HUMAN [view entry] [view interactions] High throughput yes yes
LNX2_HUMAN [view interactions] High throughput no yes
LBH_HUMAN [view interactions] High throughput no yes
CND3_HUMAN [view interactions] High throughput no yes
TBA1B_HUMAN [view entry] [view interactions] High throughput yes yes
DEF1_HUMAN [view interactions] High throughput no no
T200A_HUMAN [view interactions] High throughput no yes
NSMA2_HUMAN [view interactions] High throughput no yes
KLRG2_HUMAN [view interactions] High throughput no no
INADL_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
TADBP_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
VIR_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
MAGA3_HUMAN [view interactions] High throughput no no
ANR55_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
ECT2_HUMAN [view interactions] High throughput no no
RIGI_HUMAN [view interactions] High throughput no yes
PAR3L_HUMAN [view interactions] High throughput no yes
PMEPA_HUMAN [view interactions] High throughput no no
SPT33_HUMAN [view interactions] High throughput no no
F163B_HUMAN [view interactions] High throughput no yes
MP2K7_HUMAN [view entry] [view interactions] High throughput yes yes
PP2BB_HUMAN [view entry] [view interactions] High throughput yes yes
ZN593_HUMAN [view interactions] High throughput no yes
GSK3A_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
ATG5_HUMAN [view entry] [view interactions] High throughput yes no
CCNF_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
EZH2_HUMAN [view interactions] High throughput no no
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
UBE4B_HUMAN [view interactions] High throughput no yes
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
MTNA_HUMAN [view interactions] High throughput no yes
RHOC_HUMAN [view interactions] High throughput no no
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
P3H1_HUMAN [view interactions] High throughput no yes
SETLP_HUMAN [view interactions] High throughput no yes
MAT2B_HUMAN [view interactions] High throughput no yes
NASP_HUMAN [view interactions] High throughput no yes
NRDC_HUMAN [view interactions] High throughput no no
PDIA6_HUMAN [view entry] [view interactions] High throughput yes yes
PFD5_HUMAN [view interactions] High throughput no yes
2ABA_HUMAN [view interactions] High throughput no yes
TNPO3_HUMAN [view interactions] High throughput no yes
TNPO1_HUMAN [view entry] [view interactions] High throughput yes yes
TSN_HUMAN [view interactions] High throughput no yes
PFD3_HUMAN [view interactions] High throughput no yes
XPO5_HUMAN [view interactions] High throughput no yes
ARFP1_HUMAN [view interactions] High throughput no no
PSMD9_HUMAN [view interactions] High throughput no yes
HS12A_HUMAN [view entry] [view interactions] High throughput yes yes
PP2BC_HUMAN [view interactions] High throughput no yes
TBC17_HUMAN [view entry] [view interactions] High throughput yes yes
ITPR1_HUMAN [view entry] [view interactions] High throughput yes yes
ST4A1_HUMAN [view interactions] High throughput no yes
OGA_HUMAN [view interactions] High throughput no yes
CLU_HUMAN [view interactions] High throughput no yes
PARN_HUMAN [view entry] [view interactions] High throughput yes yes
HS74L_HUMAN [view entry] [view interactions] High throughput yes no
H14_HUMAN [view interactions] High throughput no yes
DNLI1_HUMAN [view interactions] High throughput no yes
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
OSBP1_HUMAN [view interactions] High throughput no yes
MCM3_HUMAN [view interactions] High throughput no no
MCM5_HUMAN [view interactions] High throughput no no
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
ODO1_HUMAN [view entry] [view interactions] High throughput yes yes
SNX1_HUMAN [view entry] [view interactions] High throughput yes yes
RN213_HUMAN [view interactions] High throughput no yes
ARHG1_HUMAN [view interactions] High throughput no no
PAWR_HUMAN [view interactions] High throughput no yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
COR1B_HUMAN [view entry] [view interactions] High throughput yes no
RBM8A_HUMAN [view interactions] High throughput no yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
STING_HUMAN [view interactions] High throughput no yes
ARL14_HUMAN [view interactions] High throughput no no
RFA1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes