PP2BA_HUMAN
Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals (PubMed, PubMed, PubMed, PubMed). Many of the substrates contain a PxIxIT motif and/or a LxVP motif (PubMed, PubMed, PubMed, PubMed, PubMed). In response to increased Ca(2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed). In response to increased Ca(2+) levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (PubMed). Dephosphorylates heat shock protein HSPB1 . Dephosphorylates and activates transcription factor NFATC1 (PubMed). In response to increased Ca(2+) levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed). Dephosphorylates and inactivates transcription factor ELK1 (PubMed). Dephosphorylates DARPP32 (PubMed). May dephosphorylate CRTC2 at Ser-171 resulting in CRTC2 dissociation from 14-3-3 proteins (PubMed). Dephosphorylates transcription factor TFEB at Ser-211 following Coxsackievirus B3 infection, promoting nuclear translocation (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in PP2BA_HUMAN |
---|---|---|---|---|
GO:0043169 | cation binding | 38.7500 | 4 | yes |
GO:0046872 | metal ion binding | 37.5000 | 5 | yes |
GO:0019900 | kinase binding | 31.2500 | 4 | no |
GO:0019901 | protein kinase binding | 25.0000 | 5 | no |
GO:0043168 | anion binding | 25.0000 | 4 | no |
GO:0005509 | calcium ion binding | 12.5000 | 6 | yes |
GO:0042578 | phosphoric ester hydrolase activity | 8.7500 | 4 | yes |
GO:0016791 | phosphatase activity | 7.5000 | 5 | yes |
GO:0004722 | protein serine/threonine phosphatase activity | 6.2500 | 4 | yes |
GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity | 5.0000 | 5 | yes |
GO:0017018 | myosin phosphatase activity | 5.0000 | 5 | yes |
GO:0033192 | calmodulin-dependent protein phosphatase activity | 3.7500 | 6 | yes |
GO:0051117 | ATPase binding | 3.7500 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in PP2BA_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 66.2500 | 4 | yes |
GO:0010646 | regulation of cell communication | 56.2500 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 56.2500 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 55.0000 | 4 | yes |
GO:0009966 | regulation of signal transduction | 53.7500 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 53.7500 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 52.5000 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 47.5000 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 47.5000 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 45.0000 | 5 | yes |
GO:0009889 | regulation of biosynthetic process | 42.5000 | 4 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 41.2500 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 41.2500 | 5 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 41.2500 | 5 | yes |
GO:0010468 | regulation of gene expression | 38.7500 | 6 | yes |
GO:0048584 | positive regulation of response to stimulus | 38.7500 | 4 | yes |
GO:0022607 | cellular component assembly | 37.5000 | 4 | no |
GO:0051049 | regulation of transport | 37.5000 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 36.2500 | 5 | yes |
GO:0051246 | regulation of protein metabolic process | 36.2500 | 5 | no |
GO:0010647 | positive regulation of cell communication | 36.2500 | 5 | yes |
GO:0023056 | positive regulation of signaling | 36.2500 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 33.7500 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 33.7500 | 5 | yes |
GO:0006996 | organelle organization | 32.5000 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 32.5000 | 5 | yes |
GO:0048585 | negative regulation of response to stimulus | 32.5000 | 4 | yes |
GO:0031399 | regulation of protein modification process | 31.2500 | 6 | no |
GO:0009967 | positive regulation of signal transduction | 31.2500 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.2500 | 5 | yes |
GO:0043412 | macromolecule modification | 31.2500 | 4 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 30.0000 | 4 | yes |
GO:0019220 | regulation of phosphate metabolic process | 30.0000 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 30.0000 | 5 | no |
GO:0023057 | negative regulation of signaling | 30.0000 | 4 | yes |
GO:0034762 | regulation of transmembrane transport | 30.0000 | 4 | yes |
GO:0036211 | protein modification process | 30.0000 | 4 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 30.0000 | 5 | yes |
GO:0009891 | positive regulation of biosynthetic process | 28.7500 | 5 | yes |
GO:0051247 | positive regulation of protein metabolic process | 28.7500 | 6 | no |
GO:0010648 | negative regulation of cell communication | 28.7500 | 5 | yes |
GO:0051130 | positive regulation of cellular component organization | 28.7500 | 5 | yes |
GO:0051252 | regulation of RNA metabolic process | 28.7500 | 5 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 27.5000 | 4 | yes |
GO:0008104 | protein localization | 27.5000 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 27.5000 | 5 | yes |
GO:0043933 | protein-containing complex organization | 27.5000 | 4 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 27.5000 | 6 | yes |
GO:0043269 | regulation of monoatomic ion transport | 27.5000 | 5 | yes |
GO:0071310 | cellular response to organic substance | 26.2500 | 4 | yes |
GO:0006355 | regulation of DNA-templated transcription | 26.2500 | 7 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 26.2500 | 6 | yes |
GO:0043085 | positive regulation of catalytic activity | 26.2500 | 4 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.2500 | 6 | yes |
GO:0051050 | positive regulation of transport | 26.2500 | 4 | yes |
GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
GO:0034765 | regulation of monoatomic ion transmembrane transport | 25.0000 | 5 | yes |
GO:0060341 | regulation of cellular localization | 25.0000 | 4 | yes |
GO:0141124 | intracellular signaling cassette | 23.7500 | 4 | yes |
GO:0031401 | positive regulation of protein modification process | 23.7500 | 7 | no |
GO:0042325 | regulation of phosphorylation | 23.7500 | 7 | no |
GO:0009890 | negative regulation of biosynthetic process | 23.7500 | 5 | yes |
GO:0009894 | regulation of catabolic process | 23.7500 | 4 | no |
GO:0010243 | response to organonitrogen compound | 23.7500 | 4 | yes |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 23.7500 | 6 | yes |
GO:0010959 | regulation of metal ion transport | 23.7500 | 6 | yes |
GO:0031327 | negative regulation of cellular biosynthetic process | 23.7500 | 6 | yes |
GO:0032880 | regulation of protein localization | 23.7500 | 5 | yes |
GO:1904062 | regulation of monoatomic cation transmembrane transport | 22.5000 | 6 | yes |
GO:0043067 | regulation of programmed cell death | 22.5000 | 4 | no |
GO:0051338 | regulation of transferase activity | 22.5000 | 4 | no |
GO:0031344 | regulation of cell projection organization | 22.5000 | 5 | yes |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 22.5000 | 5 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.2500 | 6 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 21.2500 | 4 | yes |
GO:0001932 | regulation of protein phosphorylation | 21.2500 | 7 | no |
GO:0042981 | regulation of apoptotic process | 21.2500 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 21.2500 | 4 | no |
GO:0051248 | negative regulation of protein metabolic process | 21.2500 | 6 | no |
GO:0043270 | positive regulation of monoatomic ion transport | 20.0000 | 5 | yes |
GO:0051129 | negative regulation of cellular component organization | 20.0000 | 5 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 20.0000 | 4 | yes |
GO:0051924 | regulation of calcium ion transport | 20.0000 | 7 | yes |
GO:0080134 | regulation of response to stress | 18.7500 | 4 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 18.7500 | 6 | yes |
GO:1902680 | positive regulation of RNA biosynthetic process | 18.7500 | 7 | yes |
GO:1903169 | regulation of calcium ion transmembrane transport | 18.7500 | 7 | yes |
GO:0006357 | regulation of transcription by RNA polymerase II | 18.7500 | 8 | yes |
GO:0030030 | cell projection organization | 18.7500 | 4 | yes |
GO:0033365 | protein localization to organelle | 18.7500 | 5 | yes |
GO:0044057 | regulation of system process | 18.7500 | 4 | yes |
GO:0045893 | positive regulation of DNA-templated transcription | 18.7500 | 8 | yes |
GO:0051094 | positive regulation of developmental process | 18.7500 | 4 | yes |
GO:0051254 | positive regulation of RNA metabolic process | 18.7500 | 6 | yes |
GO:0071702 | organic substance transport | 17.5000 | 4 | yes |
GO:0010038 | response to metal ion | 17.5000 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 17.5000 | 4 | yes |
GO:0034764 | positive regulation of transmembrane transport | 17.5000 | 5 | yes |
GO:0042127 | regulation of cell population proliferation | 17.5000 | 4 | yes |
GO:0051051 | negative regulation of transport | 17.5000 | 4 | yes |
GO:0071705 | nitrogen compound transport | 16.2500 | 4 | yes |
GO:0006811 | monoatomic ion transport | 16.2500 | 4 | yes |
GO:0010629 | negative regulation of gene expression | 16.2500 | 7 | yes |
GO:0034767 | positive regulation of monoatomic ion transmembrane transport | 16.2500 | 6 | yes |
GO:0045595 | regulation of cell differentiation | 16.2500 | 4 | yes |
GO:0045944 | positive regulation of transcription by RNA polymerase II | 16.2500 | 9 | yes |
GO:2000026 | regulation of multicellular organismal development | 15.0000 | 4 | yes |
GO:0050848 | regulation of calcium-mediated signaling | 15.0000 | 6 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 15.0000 | 4 | yes |
GO:0051928 | positive regulation of calcium ion transport | 15.0000 | 6 | yes |
GO:1904064 | positive regulation of cation transmembrane transport | 13.7500 | 7 | yes |
GO:1904427 | positive regulation of calcium ion transmembrane transport | 13.7500 | 7 | yes |
GO:0010628 | positive regulation of gene expression | 13.7500 | 7 | yes |
GO:0010975 | regulation of neuron projection development | 13.7500 | 7 | yes |
GO:0030155 | regulation of cell adhesion | 13.7500 | 4 | yes |
GO:0051093 | negative regulation of developmental process | 13.7500 | 4 | yes |
GO:0060284 | regulation of cell development | 13.7500 | 5 | yes |
GO:0070201 | regulation of establishment of protein localization | 13.7500 | 6 | yes |
GO:0015031 | protein transport | 12.5000 | 4 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 12.5000 | 4 | yes |
GO:0090257 | regulation of muscle system process | 11.2500 | 5 | yes |
GO:0002684 | positive regulation of immune system process | 11.2500 | 4 | yes |
GO:0006812 | monoatomic cation transport | 11.2500 | 5 | yes |
GO:0008284 | positive regulation of cell population proliferation | 11.2500 | 5 | yes |
GO:0019722 | calcium-mediated signaling | 11.2500 | 5 | yes |
GO:0030001 | metal ion transport | 11.2500 | 6 | yes |
GO:0030100 | regulation of endocytosis | 11.2500 | 5 | yes |
GO:0034763 | negative regulation of transmembrane transport | 11.2500 | 5 | yes |
GO:0045597 | positive regulation of cell differentiation | 11.2500 | 5 | yes |
GO:0051046 | regulation of secretion | 11.2500 | 5 | yes |
GO:0051960 | regulation of nervous system development | 11.2500 | 5 | yes |
GO:0060078 | regulation of postsynaptic membrane potential | 11.2500 | 4 | yes |
GO:1903530 | regulation of secretion by cell | 10.0000 | 4 | yes |
GO:1903828 | negative regulation of protein localization | 10.0000 | 5 | yes |
GO:0006886 | intracellular protein transport | 10.0000 | 4 | yes |
GO:2000145 | regulation of cell motility | 10.0000 | 4 | yes |
GO:0030334 | regulation of cell migration | 10.0000 | 5 | yes |
GO:0045785 | positive regulation of cell adhesion | 10.0000 | 5 | yes |
GO:0050767 | regulation of neurogenesis | 10.0000 | 6 | yes |
GO:0051047 | positive regulation of secretion | 10.0000 | 5 | yes |
GO:0051223 | regulation of protein transport | 10.0000 | 5 | yes |
GO:0070884 | regulation of calcineurin-NFAT signaling cascade | 8.7500 | 8 | yes |
GO:0072594 | establishment of protein localization to organelle | 8.7500 | 4 | yes |
GO:0090279 | regulation of calcium ion import | 8.7500 | 8 | yes |
GO:0106056 | regulation of calcineurin-mediated signaling | 8.7500 | 7 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 8.7500 | 4 | yes |
GO:1903170 | negative regulation of calcium ion transmembrane transport | 8.7500 | 7 | yes |
GO:0002694 | regulation of leukocyte activation | 8.7500 | 4 | yes |
GO:1904063 | negative regulation of cation transmembrane transport | 8.7500 | 7 | yes |
GO:0006816 | calcium ion transport | 8.7500 | 7 | yes |
GO:0031345 | negative regulation of cell projection organization | 8.7500 | 6 | yes |
GO:0034766 | negative regulation of monoatomic ion transmembrane transport | 8.7500 | 6 | yes |
GO:0043271 | negative regulation of monoatomic ion transport | 8.7500 | 5 | yes |
GO:0050865 | regulation of cell activation | 8.7500 | 4 | yes |
GO:0051926 | negative regulation of calcium ion transport | 8.7500 | 6 | yes |
GO:0060079 | excitatory postsynaptic potential | 8.7500 | 5 | yes |
GO:1905664 | regulation of calcium ion import across plasma membrane | 7.5000 | 8 | yes |
GO:0010720 | positive regulation of cell development | 7.5000 | 6 | yes |
GO:0030855 | epithelial cell differentiation | 7.5000 | 4 | yes |
GO:0034504 | protein localization to nucleus | 7.5000 | 6 | yes |
GO:0044772 | mitotic cell cycle phase transition | 7.5000 | 4 | yes |
GO:0045596 | negative regulation of cell differentiation | 7.5000 | 5 | yes |
GO:0048812 | neuron projection morphogenesis | 7.5000 | 5 | yes |
GO:0050708 | regulation of protein secretion | 7.5000 | 5 | yes |
GO:0051249 | regulation of lymphocyte activation | 7.5000 | 5 | yes |
GO:0051592 | response to calcium ion | 7.5000 | 5 | yes |
GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade | 6.2500 | 9 | yes |
GO:0090087 | regulation of peptide transport | 6.2500 | 5 | yes |
GO:0090276 | regulation of peptide hormone secretion | 6.2500 | 5 | yes |
GO:0090280 | positive regulation of calcium ion import | 6.2500 | 7 | yes |
GO:0106058 | positive regulation of calcineurin-mediated signaling | 6.2500 | 8 | yes |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 6.2500 | 6 | yes |
GO:0002696 | positive regulation of leukocyte activation | 6.2500 | 5 | yes |
GO:0002791 | regulation of peptide secretion | 6.2500 | 6 | yes |
GO:0006606 | protein import into nucleus | 6.2500 | 5 | yes |
GO:1905665 | positive regulation of calcium ion import across plasma membrane | 6.2500 | 8 | yes |
GO:0006913 | nucleocytoplasmic transport | 6.2500 | 5 | yes |
GO:2000147 | positive regulation of cell motility | 6.2500 | 5 | yes |
GO:0008277 | regulation of G protein-coupled receptor signaling pathway | 6.2500 | 5 | yes |
GO:0010721 | negative regulation of cell development | 6.2500 | 6 | yes |
GO:0016311 | dephosphorylation | 6.2500 | 5 | yes |
GO:0022407 | regulation of cell-cell adhesion | 6.2500 | 5 | yes |
GO:0030335 | positive regulation of cell migration | 6.2500 | 6 | yes |
GO:0040017 | positive regulation of locomotion | 6.2500 | 4 | yes |
GO:0042110 | T cell activation | 6.2500 | 4 | yes |
GO:0046883 | regulation of hormone secretion | 6.2500 | 4 | yes |
GO:0050796 | regulation of insulin secretion | 6.2500 | 6 | yes |
GO:0050850 | positive regulation of calcium-mediated signaling | 6.2500 | 7 | yes |
GO:0050863 | regulation of T cell activation | 6.2500 | 6 | yes |
GO:0050867 | positive regulation of cell activation | 6.2500 | 5 | yes |
GO:0051169 | nuclear transport | 6.2500 | 4 | yes |
GO:0051170 | import into nucleus | 6.2500 | 6 | yes |
GO:0051251 | positive regulation of lymphocyte activation | 6.2500 | 6 | yes |
GO:0055001 | muscle cell development | 6.2500 | 4 | yes |
GO:0090281 | negative regulation of calcium ion import | 5.0000 | 7 | yes |
GO:0097720 | calcineurin-mediated signaling | 5.0000 | 6 | yes |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 5.0000 | 7 | yes |
GO:1903531 | negative regulation of secretion by cell | 5.0000 | 5 | yes |
GO:1904950 | negative regulation of establishment of protein localization | 5.0000 | 6 | yes |
GO:0006470 | protein dephosphorylation | 5.0000 | 5 | yes |
GO:1905949 | negative regulation of calcium ion import across plasma membrane | 5.0000 | 8 | yes |
GO:0014904 | myotube cell development | 5.0000 | 5 | yes |
GO:0022409 | positive regulation of cell-cell adhesion | 5.0000 | 6 | yes |
GO:0033173 | calcineurin-NFAT signaling cascade | 5.0000 | 7 | yes |
GO:0042593 | glucose homeostasis | 5.0000 | 4 | yes |
GO:0045744 | negative regulation of G protein-coupled receptor signaling pathway | 5.0000 | 6 | yes |
GO:0048741 | skeletal muscle fiber development | 5.0000 | 6 | yes |
GO:0050768 | negative regulation of neurogenesis | 5.0000 | 6 | yes |
GO:0050773 | regulation of dendrite development | 5.0000 | 4 | yes |
GO:0050870 | positive regulation of T cell activation | 5.0000 | 7 | yes |
GO:0051048 | negative regulation of secretion | 5.0000 | 5 | yes |
GO:0051961 | negative regulation of nervous system development | 5.0000 | 5 | yes |
GO:0070663 | regulation of leukocyte proliferation | 3.7500 | 5 | yes |
GO:0071322 | cellular response to carbohydrate stimulus | 3.7500 | 5 | yes |
GO:0071326 | cellular response to monosaccharide stimulus | 3.7500 | 6 | yes |
GO:0071331 | cellular response to hexose stimulus | 3.7500 | 7 | yes |
GO:0071333 | cellular response to glucose stimulus | 3.7500 | 5 | yes |
GO:0090278 | negative regulation of peptide hormone secretion | 3.7500 | 6 | yes |
GO:0099170 | postsynaptic modulation of chemical synaptic transmission | 3.7500 | 6 | yes |
GO:1902105 | regulation of leukocyte differentiation | 3.7500 | 5 | yes |
GO:0001678 | intracellular glucose homeostasis | 3.7500 | 4 | yes |
GO:0001975 | response to amphetamine | 3.7500 | 6 | yes |
GO:1903706 | regulation of hemopoiesis | 3.7500 | 4 | yes |
GO:0002792 | negative regulation of peptide secretion | 3.7500 | 6 | yes |
GO:0009743 | response to carbohydrate | 3.7500 | 4 | yes |
GO:0009746 | response to hexose | 3.7500 | 6 | yes |
GO:0009749 | response to glucose | 3.7500 | 7 | yes |
GO:0010611 | regulation of cardiac muscle hypertrophy | 3.7500 | 5 | yes |
GO:0010613 | positive regulation of cardiac muscle hypertrophy | 3.7500 | 6 | yes |
GO:0014075 | response to amine | 3.7500 | 5 | yes |
GO:0014742 | positive regulation of muscle hypertrophy | 3.7500 | 5 | yes |
GO:0014743 | regulation of muscle hypertrophy | 3.7500 | 6 | yes |
GO:0032944 | regulation of mononuclear cell proliferation | 3.7500 | 6 | yes |
GO:0034284 | response to monosaccharide | 3.7500 | 5 | yes |
GO:0042060 | wound healing | 3.7500 | 4 | yes |
GO:0042129 | regulation of T cell proliferation | 3.7500 | 7 | yes |
GO:0043502 | regulation of muscle adaptation | 3.7500 | 4 | yes |
GO:0045667 | regulation of osteoblast differentiation | 3.7500 | 5 | yes |
GO:0045807 | positive regulation of endocytosis | 3.7500 | 5 | yes |
GO:0046006 | regulation of activated T cell proliferation | 3.7500 | 8 | yes |
GO:0046676 | negative regulation of insulin secretion | 3.7500 | 7 | yes |
GO:0046888 | negative regulation of hormone secretion | 3.7500 | 5 | yes |
GO:0048814 | regulation of dendrite morphogenesis | 3.7500 | 5 | yes |
GO:0050670 | regulation of lymphocyte proliferation | 3.7500 | 6 | yes |
GO:0050709 | negative regulation of protein secretion | 3.7500 | 6 | yes |
GO:0051224 | negative regulation of protein transport | 3.7500 | 5 | yes |
GO:0070665 | positive regulation of leukocyte proliferation | 2.5000 | 6 | yes |
GO:0090183 | regulation of kidney development | 2.5000 | 4 | yes |
GO:0090184 | positive regulation of kidney development | 2.5000 | 5 | yes |
GO:0090192 | regulation of glomerulus development | 2.5000 | 5 | yes |
GO:0090193 | positive regulation of glomerulus development | 2.5000 | 6 | yes |
GO:0097205 | renal filtration | 2.5000 | 4 | yes |
GO:0110061 | regulation of angiotensin-activated signaling pathway | 2.5000 | 6 | yes |
GO:0110062 | negative regulation of angiotensin-activated signaling pathway | 2.5000 | 7 | yes |
GO:1902107 | positive regulation of leukocyte differentiation | 2.5000 | 6 | yes |
GO:0000082 | G1/S transition of mitotic cell cycle | 2.5000 | 5 | yes |
GO:1903242 | regulation of cardiac muscle hypertrophy in response to stress | 2.5000 | 5 | yes |
GO:1903244 | positive regulation of cardiac muscle hypertrophy in response to stress | 2.5000 | 6 | yes |
GO:0002761 | regulation of myeloid leukocyte differentiation | 2.5000 | 6 | yes |
GO:1903708 | positive regulation of hemopoiesis | 2.5000 | 5 | yes |
GO:0002763 | positive regulation of myeloid leukocyte differentiation | 2.5000 | 7 | yes |
GO:0003300 | cardiac muscle hypertrophy | 2.5000 | 6 | yes |
GO:1905203 | regulation of connective tissue replacement | 2.5000 | 5 | yes |
GO:1905205 | positive regulation of connective tissue replacement | 2.5000 | 6 | yes |
GO:0008544 | epidermis development | 2.5000 | 4 | yes |
GO:0009913 | epidermal cell differentiation | 2.5000 | 5 | yes |
GO:0010612 | regulation of cardiac muscle adaptation | 2.5000 | 5 | yes |
GO:0010615 | positive regulation of cardiac muscle adaptation | 2.5000 | 6 | yes |
GO:0014733 | regulation of skeletal muscle adaptation | 2.5000 | 5 | yes |
GO:0014744 | positive regulation of muscle adaptation | 2.5000 | 5 | yes |
GO:0014883 | transition between fast and slow fiber | 2.5000 | 6 | yes |
GO:0014887 | cardiac muscle adaptation | 2.5000 | 4 | yes |
GO:0014896 | muscle hypertrophy | 2.5000 | 4 | yes |
GO:0014897 | striated muscle hypertrophy | 2.5000 | 5 | yes |
GO:0014898 | cardiac muscle hypertrophy in response to stress | 2.5000 | 4 | yes |
GO:0030216 | keratinocyte differentiation | 2.5000 | 6 | yes |
GO:0032946 | positive regulation of mononuclear cell proliferation | 2.5000 | 7 | yes |
GO:0034103 | regulation of tissue remodeling | 2.5000 | 4 | yes |
GO:0034105 | positive regulation of tissue remodeling | 2.5000 | 5 | yes |
GO:0042102 | positive regulation of T cell proliferation | 2.5000 | 8 | yes |
GO:0042104 | positive regulation of activated T cell proliferation | 2.5000 | 9 | yes |
GO:0043403 | skeletal muscle tissue regeneration | 2.5000 | 4 | yes |
GO:0044058 | regulation of digestive system process | 2.5000 | 5 | yes |
GO:0044843 | cell cycle G1/S phase transition | 2.5000 | 4 | yes |
GO:0045637 | regulation of myeloid cell differentiation | 2.5000 | 5 | yes |
GO:0045639 | positive regulation of myeloid cell differentiation | 2.5000 | 6 | yes |
GO:0045669 | positive regulation of osteoblast differentiation | 2.5000 | 6 | yes |
GO:0045670 | regulation of osteoclast differentiation | 2.5000 | 7 | yes |
GO:0045672 | positive regulation of osteoclast differentiation | 2.5000 | 8 | yes |
GO:0046877 | regulation of saliva secretion | 2.5000 | 4 | yes |
GO:0046878 | positive regulation of saliva secretion | 2.5000 | 5 | yes |
GO:0048813 | dendrite morphogenesis | 2.5000 | 6 | yes |
GO:0050671 | positive regulation of lymphocyte proliferation | 2.5000 | 7 | yes |
GO:0050774 | negative regulation of dendrite morphogenesis | 2.5000 | 6 | yes |
GO:0060456 | positive regulation of digestive system process | 2.5000 | 5 | yes |
GO:0061006 | regulation of cell proliferation involved in kidney morphogenesis | 2.5000 | 5 | yes |
GO:0070262 | peptidyl-serine dephosphorylation | 2.5000 | 6 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
UBP14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CRTC2_HUMAN | [view interactions] | Low throughput | no | yes |
AKAP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CAC1C_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CANB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CCG8_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NFAC1_HUMAN | [view interactions] | Low throughput | no | no |
NFAC2_HUMAN | [view interactions] | Low throughput | no | yes |
JUN_HUMAN | [view interactions] | Low throughput | no | yes |
UTRN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SYNJ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNJ8_HUMAN | [view interactions] | Low throughput | no | yes |
LASP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RCAN1_HUMAN | [view interactions] | Low throughput | no | yes |
CABIN_HUMAN | [view interactions] | Low throughput | no | yes |
FBX32_HUMAN | [view interactions] | Low throughput | no | no |
PSA6_HUMAN | [view interactions] | Low throughput | no | yes |
MARH7_HUMAN | [view interactions] | Low throughput | no | yes |
TRI72_HUMAN | [view interactions] | Low throughput | no | no |
BCL2_HUMAN | [view interactions] | Low throughput | no | no |
MYOZ2_HUMAN | [view interactions] | Low throughput | no | no |
MYOZ1_HUMAN | [view interactions] | Low throughput | no | no |
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PHLP2_HUMAN | [view interactions] | Low throughput | no | yes |
PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PDE4D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRAF3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GBRG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GBRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GBRA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RCAN2_HUMAN | [view interactions] | Low throughput | no | yes |
SC6A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
FKBP5_HUMAN | [view interactions] | Low throughput | no | yes |
CSEN_HUMAN | [view interactions] | Low throughput | no | no |
DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KLHL3_HUMAN | [view interactions] | Low throughput | no | no |
PPIA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ADRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PP2BA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SL9A1_HUMAN | [view interactions] | Low throughput | no | no |
ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IRF2_HUMAN | [view interactions] | High throughput | no | yes |
SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ELK1_HUMAN | [view interactions] | High throughput | no | yes |
GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
M3K12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDK1_HUMAN | [view interactions] | High throughput | no | no |
SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEUL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
MET_HUMAN | [view interactions] | High throughput | no | yes |
CP074_HUMAN | [view interactions] | High throughput | no | no |
LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
ERBB3_HUMAN | [view interactions] | High throughput | no | yes |
FGFR4_HUMAN | [view interactions] | High throughput | no | no |
RYK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PTK7_HUMAN | [view interactions] | High throughput | no | yes |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BTG3_HUMAN | [view interactions] | High throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RXRB_HUMAN | [view interactions] | High throughput | no | yes |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SWAP1_HUMAN | [view interactions] | High throughput | no | no |
AMPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U119A_HUMAN | [view interactions] | High throughput | no | no |
TENS4_HUMAN | [view interactions] | High throughput | no | no |
ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IP3KB_HUMAN | [view interactions] | High throughput | no | no |
PLAC8_HUMAN | [view interactions] | High throughput | no | no |
ARMT1_HUMAN | [view interactions] | High throughput | no | yes |
F167A_HUMAN | [view interactions] | High throughput | no | yes |
SHAN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CANB2_HUMAN | [view interactions] | High throughput | no | no |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MK07_HUMAN | [view interactions] | High throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEP76_HUMAN | [view interactions] | High throughput | no | yes |
P53_HUMAN | [view interactions] | High throughput | no | no |
TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PBIR1_HUMAN | [view interactions] | High throughput | no | yes |
RASF2_HUMAN | [view interactions] | High throughput | no | yes |
ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RCAN3_HUMAN | [view interactions] | High throughput | no | no |
NFAC4_HUMAN | [view interactions] | High throughput | no | yes |
SIK3_HUMAN | [view interactions] | High throughput | no | yes |
LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LNX2_HUMAN | [view interactions] | High throughput | no | yes |
LBH_HUMAN | [view interactions] | High throughput | no | yes |
CND3_HUMAN | [view interactions] | High throughput | no | yes |
TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEF1_HUMAN | [view interactions] | High throughput | no | no |
T200A_HUMAN | [view interactions] | High throughput | no | yes |
NSMA2_HUMAN | [view interactions] | High throughput | no | yes |
KLRG2_HUMAN | [view interactions] | High throughput | no | no |
INADL_HUMAN | [view interactions] | High throughput | no | no |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
TADBP_HUMAN | [view interactions] | High throughput | no | yes |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
MAGA3_HUMAN | [view interactions] | High throughput | no | no |
ANR55_HUMAN | [view interactions] | High throughput | no | yes |
CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECT2_HUMAN | [view interactions] | High throughput | no | no |
RIGI_HUMAN | [view interactions] | High throughput | no | yes |
PAR3L_HUMAN | [view interactions] | High throughput | no | yes |
PMEPA_HUMAN | [view interactions] | High throughput | no | no |
SPT33_HUMAN | [view interactions] | High throughput | no | no |
F163B_HUMAN | [view interactions] | High throughput | no | yes |
MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN593_HUMAN | [view interactions] | High throughput | no | yes |
GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CCNF_HUMAN | [view interactions] | High throughput | no | no |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EZH2_HUMAN | [view interactions] | High throughput | no | no |
OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBE4B_HUMAN | [view interactions] | High throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTNA_HUMAN | [view interactions] | High throughput | no | yes |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P3H1_HUMAN | [view interactions] | High throughput | no | yes |
SETLP_HUMAN | [view interactions] | High throughput | no | yes |
MAT2B_HUMAN | [view interactions] | High throughput | no | yes |
NASP_HUMAN | [view interactions] | High throughput | no | yes |
NRDC_HUMAN | [view interactions] | High throughput | no | no |
PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PFD5_HUMAN | [view interactions] | High throughput | no | yes |
2ABA_HUMAN | [view interactions] | High throughput | no | yes |
TNPO3_HUMAN | [view interactions] | High throughput | no | yes |
TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSN_HUMAN | [view interactions] | High throughput | no | yes |
PFD3_HUMAN | [view interactions] | High throughput | no | yes |
XPO5_HUMAN | [view interactions] | High throughput | no | yes |
ARFP1_HUMAN | [view interactions] | High throughput | no | no |
PSMD9_HUMAN | [view interactions] | High throughput | no | yes |
HS12A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP2BC_HUMAN | [view interactions] | High throughput | no | yes |
TBC17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ST4A1_HUMAN | [view interactions] | High throughput | no | yes |
OGA_HUMAN | [view interactions] | High throughput | no | yes |
CLU_HUMAN | [view interactions] | High throughput | no | yes |
PARN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H14_HUMAN | [view interactions] | High throughput | no | yes |
DNLI1_HUMAN | [view interactions] | High throughput | no | yes |
LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OSBP1_HUMAN | [view interactions] | High throughput | no | yes |
MCM3_HUMAN | [view interactions] | High throughput | no | no |
MCM5_HUMAN | [view interactions] | High throughput | no | no |
ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBMX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ODO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RN213_HUMAN | [view interactions] | High throughput | no | yes |
ARHG1_HUMAN | [view interactions] | High throughput | no | no |
PAWR_HUMAN | [view interactions] | High throughput | no | yes |
TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STING_HUMAN | [view interactions] | High throughput | no | yes |
ARL14_HUMAN | [view interactions] | High throughput | no | no |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
RFA2_HUMAN | [view interactions] | High throughput | no | yes |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |