COR1B_HUMAN
Evidence for PS localization
Functions
Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in COR1B_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 37.2881 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 27.1186 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 27.1186 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 25.4237 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.4237 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.4237 | 4 | no |
| GO:0003723 | RNA binding | 23.7288 | 4 | no |
| GO:0005524 | ATP binding | 23.7288 | 5 | no |
| GO:0045296 | cadherin binding | 18.6441 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in COR1B_HUMAN |
|---|---|---|---|---|
| GO:0051128 | regulation of cellular component organization | 52.5424 | 4 | yes |
| GO:0006996 | organelle organization | 50.8475 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 47.4576 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 45.7627 | 4 | yes |
| GO:0007010 | cytoskeleton organization | 38.9831 | 5 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 38.9831 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 38.9831 | 4 | no |
| GO:0033043 | regulation of organelle organization | 37.2881 | 5 | yes |
| GO:0022607 | cellular component assembly | 35.5932 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 35.5932 | 4 | no |
| GO:0008104 | protein localization | 33.8983 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 33.8983 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 33.8983 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 30.5085 | 6 | yes |
| GO:0010468 | regulation of gene expression | 28.8136 | 5 | no |
| GO:0097435 | supramolecular fiber organization | 27.1186 | 4 | yes |
| GO:0032970 | regulation of actin filament-based process | 25.4237 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 25.4237 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 25.4237 | 4 | no |
| GO:0007015 | actin filament organization | 23.7288 | 5 | yes |
| GO:0030030 | cell projection organization | 23.7288 | 4 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 23.7288 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 23.7288 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 23.7288 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.7288 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.0339 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 22.0339 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 22.0339 | 4 | yes |
| GO:0110053 | regulation of actin filament organization | 22.0339 | 6 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 22.0339 | 5 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 22.0339 | 5 | yes |
| GO:0036211 | protein modification process | 22.0339 | 4 | no |
| GO:0043412 | macromolecule modification | 22.0339 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 22.0339 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 22.0339 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 22.0339 | 5 | no |
| GO:0010646 | regulation of cell communication | 22.0339 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 20.3390 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 20.3390 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 20.3390 | 4 | no |
| GO:0009966 | regulation of signal transduction | 20.3390 | 4 | no |
| GO:0071702 | organic substance transport | 20.3390 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 18.6441 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 18.6441 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 18.6441 | 6 | yes |
| GO:0022604 | regulation of cell morphogenesis | 16.9492 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 16.9492 | 4 | yes |
| GO:0030334 | regulation of cell migration | 15.2542 | 5 | yes |
| GO:2000145 | regulation of cell motility | 15.2542 | 4 | yes |
| GO:0010639 | negative regulation of organelle organization | 13.5593 | 6 | yes |
| GO:0048585 | negative regulation of response to stimulus | 13.5593 | 4 | yes |
| GO:0031346 | positive regulation of cell projection organization | 10.1695 | 6 | yes |
| GO:0032101 | regulation of response to external stimulus | 10.1695 | 4 | yes |
| GO:0051494 | negative regulation of cytoskeleton organization | 10.1695 | 7 | yes |
| GO:0001667 | ameboidal-type cell migration | 8.4746 | 4 | yes |
| GO:0030336 | negative regulation of cell migration | 8.4746 | 6 | yes |
| GO:0040013 | negative regulation of locomotion | 8.4746 | 4 | yes |
| GO:1902743 | regulation of lamellipodium organization | 8.4746 | 7 | yes |
| GO:1902745 | positive regulation of lamellipodium organization | 8.4746 | 7 | yes |
| GO:1902904 | negative regulation of supramolecular fiber organization | 8.4746 | 6 | yes |
| GO:2000146 | negative regulation of cell motility | 8.4746 | 5 | yes |
| GO:0070848 | response to growth factor | 6.7797 | 4 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 6.7797 | 5 | yes |
| GO:0031529 | ruffle organization | 5.0847 | 6 | yes |
| GO:0042060 | wound healing | 5.0847 | 4 | yes |
| GO:0050920 | regulation of chemotaxis | 5.0847 | 4 | yes |
| GO:0010631 | epithelial cell migration | 3.3898 | 5 | yes |
| GO:0014910 | regulation of smooth muscle cell migration | 3.3898 | 6 | yes |
| GO:0014912 | negative regulation of smooth muscle cell migration | 3.3898 | 7 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 3.3898 | 5 | yes |
| GO:0036120 | cellular response to platelet-derived growth factor stimulus | 3.3898 | 4 | yes |
| GO:0043542 | endothelial cell migration | 3.3898 | 6 | yes |
| GO:0051017 | actin filament bundle assembly | 3.3898 | 5 | yes |
| GO:0051125 | regulation of actin nucleation | 3.3898 | 7 | yes |
| GO:0051126 | negative regulation of actin nucleation | 3.3898 | 7 | yes |
| GO:0060326 | cell chemotaxis | 3.3898 | 4 | yes |
| GO:0061572 | actin filament bundle organization | 3.3898 | 6 | yes |
| GO:2000392 | regulation of lamellipodium morphogenesis | 3.3898 | 6 | yes |
| GO:2000394 | positive regulation of lamellipodium morphogenesis | 3.3898 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in COR1B_HUMAN |
|---|---|---|---|---|
| DOID:114 | heart disease | 3.3898 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SSH1_HUMAN | [view interactions] | Low throughput | no | yes |
| COR1C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRI15_HUMAN | [view interactions] | Low throughput | no | no |
| IMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPAC1_HUMAN | [view interactions] | High throughput | no | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| LORF1_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSN7A_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT9_HUMAN | [view interactions] | High throughput | no | no |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| CE170_HUMAN | [view interactions] | High throughput | no | yes |
| COR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| DOK2_HUMAN | [view interactions] | High throughput | no | no |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| SRS12_HUMAN | [view interactions] | High throughput | no | no |
| CP1A2_HUMAN | [view interactions] | High throughput | no | no |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| PKHG7_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| ATF3_HUMAN | [view interactions] | High throughput | no | yes |
| MB212_HUMAN | [view interactions] | High throughput | no | no |
| VMP1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| LHX4_HUMAN | [view interactions] | High throughput | no | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFT57_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| LUZP4_HUMAN | [view interactions] | High throughput | no | no |
| MTMR7_HUMAN | [view interactions] | High throughput | no | no |
| CORO6_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXB1_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THAP8_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2A_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1C_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| SAFB1_HUMAN | [view interactions] | High throughput | no | yes |
| NU107_HUMAN | [view interactions] | High throughput | no | no |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPIPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VATF_HUMAN | [view interactions] | High throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TELO2_HUMAN | [view interactions] | High throughput | no | yes |
| DPYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSBP1_HUMAN | [view interactions] | High throughput | no | yes |
| OTU6B_HUMAN | [view interactions] | High throughput | no | yes |
| SYTC_HUMAN | [view interactions] | High throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZRAB2_HUMAN | [view interactions] | High throughput | no | yes |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| PAPOA_HUMAN | [view interactions] | High throughput | no | yes |
| PARVA_HUMAN | [view interactions] | High throughput | no | yes |
| SWP70_HUMAN | [view interactions] | High throughput | no | no |
| TBC17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASPD_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| RM01_HUMAN | [view interactions] | High throughput | no | yes |
| NFYB_HUMAN | [view interactions] | High throughput | no | yes |
| NFYC_HUMAN | [view interactions] | High throughput | no | no |
| NH2L1_HUMAN | [view interactions] | High throughput | no | yes |
| KPBB_HUMAN | [view interactions] | High throughput | no | no |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| SFPA2_HUMAN | [view interactions] | High throughput | no | no |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LSM2_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIPRL_HUMAN | [view interactions] | High throughput | no | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| MCCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CMC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYB5_HUMAN | [view interactions] | High throughput | no | no |
| ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| SYK_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUBA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYPM_HUMAN | [view interactions] | High throughput | no | yes |
| PGAM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYRC_HUMAN | [view interactions] | High throughput | no | yes |
| TPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RNF41_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BICD1_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| RHDF2_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| COF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |