PP1B_HUMAN
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the Ser-418 residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in PP1B_HUMAN |
---|---|---|---|---|
GO:0003779 | actin binding | 35.2941 | 4 | no |
GO:0017076 | purine nucleotide binding | 28.8235 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 28.8235 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 28.8235 | 4 | no |
GO:0046872 | metal ion binding | 26.4706 | 4 | yes |
GO:0005524 | ATP binding | 24.1176 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 24.1176 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 24.1176 | 5 | no |
GO:0019900 | kinase binding | 20.5882 | 4 | yes |
GO:0003723 | RNA binding | 20.5882 | 4 | no |
GO:0019901 | protein kinase binding | 18.8235 | 5 | yes |
GO:0004722 | protein serine/threonine phosphatase activity | 4.7059 | 4 | yes |
GO:0016791 | phosphatase activity | 4.7059 | 5 | yes |
GO:0042578 | phosphoric ester hydrolase activity | 4.7059 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in PP1B_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 60.0000 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 53.5294 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 51.1765 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 50.5882 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 50.5882 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 49.4118 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 49.4118 | 4 | no |
GO:0006996 | organelle organization | 47.6471 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 41.7647 | 4 | no |
GO:0022607 | cellular component assembly | 39.4118 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 38.8235 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 38.2353 | 5 | no |
GO:0010646 | regulation of cell communication | 37.0588 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 37.0588 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 35.8824 | 5 | no |
GO:0010468 | regulation of gene expression | 35.2941 | 5 | yes |
GO:0033043 | regulation of organelle organization | 34.1176 | 5 | no |
GO:0008104 | protein localization | 33.5294 | 4 | no |
GO:0007010 | cytoskeleton organization | 32.9412 | 5 | no |
GO:0009966 | regulation of signal transduction | 31.7647 | 4 | no |
GO:0031399 | regulation of protein modification process | 29.4118 | 6 | no |
GO:0009892 | negative regulation of metabolic process | 28.8235 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 28.2353 | 6 | no |
GO:0009889 | regulation of biosynthetic process | 27.6471 | 4 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 27.6471 | 5 | yes |
GO:0036211 | protein modification process | 27.6471 | 4 | yes |
GO:0043412 | macromolecule modification | 27.6471 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 27.6471 | 5 | no |
GO:0051130 | positive regulation of cellular component organization | 27.0588 | 5 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.0588 | 5 | no |
GO:0097435 | supramolecular fiber organization | 27.0588 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 26.4706 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 26.4706 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 26.4706 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.8824 | 5 | no |
GO:0051493 | regulation of cytoskeleton organization | 25.8824 | 6 | no |
GO:0044087 | regulation of cellular component biogenesis | 25.2941 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 24.7059 | 5 | no |
GO:0007015 | actin filament organization | 24.1176 | 5 | no |
GO:0010941 | regulation of cell death | 24.1176 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 23.5294 | 5 | no |
GO:0032970 | regulation of actin filament-based process | 23.5294 | 4 | no |
GO:0051049 | regulation of transport | 22.9412 | 4 | no |
GO:0042325 | regulation of phosphorylation | 22.9412 | 7 | no |
GO:0043067 | regulation of programmed cell death | 22.9412 | 5 | no |
GO:0023056 | positive regulation of signaling | 22.3529 | 4 | no |
GO:1902903 | regulation of supramolecular fiber organization | 22.3529 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 21.7647 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 21.7647 | 5 | no |
GO:0043933 | protein-containing complex organization | 21.7647 | 4 | no |
GO:0042981 | regulation of apoptotic process | 21.7647 | 6 | no |
GO:0051240 | positive regulation of multicellular organismal process | 21.1765 | 4 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 21.1765 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 21.1765 | 6 | no |
GO:0051248 | negative regulation of protein metabolic process | 21.1765 | 6 | no |
GO:0030030 | cell projection organization | 21.1765 | 4 | no |
GO:0010647 | positive regulation of cell communication | 21.1765 | 5 | no |
GO:0032956 | regulation of actin cytoskeleton organization | 21.1765 | 5 | no |
GO:0006796 | phosphate-containing compound metabolic process | 20.5882 | 4 | yes |
GO:0006355 | regulation of DNA-templated transcription | 20.5882 | 6 | no |
GO:0051129 | negative regulation of cellular component organization | 20.5882 | 5 | no |
GO:0060341 | regulation of cellular localization | 20.5882 | 4 | no |
GO:0016192 | vesicle-mediated transport | 20.5882 | 4 | no |
GO:0009894 | regulation of catabolic process | 18.2353 | 4 | yes |
GO:0030155 | regulation of cell adhesion | 15.8824 | 4 | yes |
GO:0031329 | regulation of cellular catabolic process | 15.2941 | 5 | yes |
GO:2000112 | regulation of cellular macromolecule biosynthetic process | 7.6471 | 6 | yes |
GO:0009416 | response to light stimulus | 5.8824 | 4 | yes |
GO:0006109 | regulation of carbohydrate metabolic process | 4.7059 | 5 | yes |
GO:0006470 | protein dephosphorylation | 4.7059 | 5 | yes |
GO:0016311 | dephosphorylation | 4.7059 | 5 | yes |
GO:0043255 | regulation of carbohydrate biosynthetic process | 4.1176 | 5 | yes |
GO:0010675 | regulation of cellular carbohydrate metabolic process | 3.5294 | 5 | yes |
GO:0015980 | energy derivation by oxidation of organic compounds | 3.5294 | 4 | yes |
GO:0032881 | regulation of polysaccharide metabolic process | 3.5294 | 5 | yes |
GO:0032885 | regulation of polysaccharide biosynthetic process | 3.5294 | 6 | yes |
GO:0043467 | regulation of generation of precursor metabolites and energy | 3.5294 | 5 | yes |
GO:0005976 | polysaccharide metabolic process | 2.9412 | 4 | yes |
GO:0005977 | glycogen metabolic process | 2.9412 | 6 | yes |
GO:0006073 | cellular glucan metabolic process | 2.9412 | 5 | yes |
GO:0006112 | energy reserve metabolic process | 2.9412 | 5 | yes |
GO:0044042 | glucan metabolic process | 2.9412 | 5 | yes |
GO:0044264 | cellular polysaccharide metabolic process | 2.9412 | 4 | yes |
GO:0000165 | MAPK cascade | 2.3529 | 4 | yes |
GO:0005979 | regulation of glycogen biosynthetic process | 2.3529 | 7 | yes |
GO:0010962 | regulation of glucan biosynthetic process | 2.3529 | 6 | yes |
GO:0070873 | regulation of glycogen metabolic process | 2.3529 | 6 | yes |
GO:0009648 | photoperiodism | 1.7647 | 5 | yes |
GO:0043153 | entrainment of circadian clock by photoperiod | 1.7647 | 4 | yes |
GO:0043470 | regulation of carbohydrate catabolic process | 1.7647 | 5 | yes |
GO:0005981 | regulation of glycogen catabolic process | 1.1765 | 6 | yes |
GO:0043471 | regulation of cellular carbohydrate catabolic process | 1.1765 | 5 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in PP1B_HUMAN |
---|---|---|---|---|
DOID:114 | heart disease | 4.1176 | 3 | no |
DOID:0050700 | cardiomyopathy | 3.5294 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 3.5294 | 5 | no |
DOID:557 | kidney disease | 2.3529 | 3 | no |
DOID:0080000 | muscular disease | 2.3529 | 3 | no |
DOID:423 | myopathy | 2.3529 | 5 | no |
DOID:66 | muscle tissue disease | 2.3529 | 4 | no |
DOID:0050851 | glomerulosclerosis | 1.7647 | 6 | no |
DOID:10952 | nephritis | 1.7647 | 4 | no |
DOID:1312 | focal segmental glomerulosclerosis | 1.7647 | 7 | no |
DOID:2921 | glomerulonephritis | 1.7647 | 5 | no |
DOID:12930 | dilated cardiomyopathy | 1.7647 | 6 | no |
DOID:2843 | long QT syndrome | 1.1765 | 6 | no |
DOID:0060674 | catecholaminergic polymorphic ventricular tachycardia | 1.1765 | 5 | no |
DOID:10273 | heart conduction disease | 1.1765 | 4 | no |
DOID:3191 | nemaline myopathy | 1.1765 | 7 | no |
DOID:422 | congenital structural myopathy | 1.1765 | 6 | no |
DOID:0110274 | autosomal recessive limb-girdle muscular dystrophy | 1.1765 | 8 | no |
DOID:11724 | limb-girdle muscular dystrophy | 1.1765 | 7 | no |
DOID:9884 | muscular dystrophy | 1.1765 | 6 | no |
DOID:0050155 | sensory system disease | 1.1765 | 3 | no |
DOID:0050563 | nonsyndromic deafness | 1.1765 | 5 | no |
DOID:0050564 | autosomal dominant nonsyndromic deafness | 1.1765 | 6 | no |
DOID:2742 | auditory system disease | 1.1765 | 4 | no |
DOID:1247 | blood coagulation disease | 1.1765 | 3 | no |
DOID:2218 | blood platelet disease | 1.1765 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
IASPP_HUMAN | [view interactions] | Low throughput | no | yes |
PP12C_HUMAN | [view interactions] | Low throughput | no | yes |
NEB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AURKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MDM4_HUMAN | [view interactions] | Low throughput | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PR15A_HUMAN | [view interactions] | Low throughput | no | yes |
PPR3A_HUMAN | [view interactions] | Low throughput | no | no |
MYPT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MYPT2_HUMAN | [view interactions] | Low throughput | no | no |
H31_HUMAN | [view interactions] | Low throughput | no | yes |
H33_HUMAN | [view interactions] | Low throughput | no | yes |
GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LZTR1_HUMAN | [view interactions] | Low throughput | no | no |
HXA2_HUMAN | [view interactions] | Low throughput | no | no |
UBAC1_HUMAN | [view interactions] | Low throughput | no | yes |
KIF23_HUMAN | [view interactions] | Low throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NONO_HUMAN | [view interactions] | Low throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RYR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RB_HUMAN | [view interactions] | Low throughput | no | yes |
NUCL_HUMAN | [view interactions] | Low throughput | no | yes |
MERL_HUMAN | [view interactions] | Low throughput | no | yes |
E41L1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
MYL6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SNF5_HUMAN | [view interactions] | Low throughput | no | yes |
BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
NCOR1_HUMAN | [view interactions] | Low throughput | no | yes |
TIF1B_HUMAN | [view interactions] | Low throughput | no | yes |
RL5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HDAC7_HUMAN | [view interactions] | Low throughput | no | no |
2A5G_HUMAN | [view interactions] | Low throughput | no | yes |
GLUT4_HUMAN | [view interactions] | High throughput | no | no |
PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
LBR_HUMAN | [view interactions] | High throughput | no | yes |
CCNB1_HUMAN | [view interactions] | High throughput | no | no |
HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASF7_HUMAN | [view interactions] | High throughput | no | no |
PAN2_HUMAN | [view interactions] | High throughput | no | no |
RASF8_HUMAN | [view interactions] | High throughput | no | yes |
EED_HUMAN | [view interactions] | High throughput | no | yes |
RASF9_HUMAN | [view interactions] | High throughput | no | yes |
LUZP4_HUMAN | [view interactions] | High throughput | no | no |
MNDA_HUMAN | [view interactions] | High throughput | no | no |
ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
DAB2_HUMAN | [view interactions] | High throughput | no | yes |
RBM6_HUMAN | [view interactions] | High throughput | no | yes |
UNK_HUMAN | [view interactions] | High throughput | no | yes |
CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
DHX9_HUMAN | [view interactions] | High throughput | no | yes |
ACTS_HUMAN | [view interactions] | High throughput | no | no |
SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYO1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COBL_HUMAN | [view interactions] | High throughput | no | yes |
CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITPI2_HUMAN | [view interactions] | High throughput | no | yes |
CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MISP_HUMAN | [view interactions] | High throughput | no | no |
FLNB_HUMAN | [view interactions] | High throughput | no | no |
BMP2K_HUMAN | [view interactions] | High throughput | no | yes |
LMO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LUZP1_HUMAN | [view interactions] | High throughput | no | yes |
MYLK_HUMAN | [view interactions] | High throughput | no | no |
DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SH24A_HUMAN | [view interactions] | High throughput | no | no |
MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RIF1_HUMAN | [view interactions] | High throughput | no | yes |
ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZN638_HUMAN | [view interactions] | High throughput | no | yes |
TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AFAP1_HUMAN | [view interactions] | High throughput | no | yes |
EPN4_HUMAN | [view interactions] | High throughput | no | yes |
KI18A_HUMAN | [view interactions] | High throughput | no | yes |
SIR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CD59_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TES_HUMAN | [view interactions] | High throughput | no | yes |
FLII_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MET17_HUMAN | [view interactions] | High throughput | no | yes |
PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEXN_HUMAN | [view interactions] | High throughput | no | yes |
KI18B_HUMAN | [view interactions] | High throughput | no | no |
GA2L3_HUMAN | [view interactions] | High throughput | no | no |
YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UACA_HUMAN | [view interactions] | High throughput | no | yes |
CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STON2_HUMAN | [view interactions] | High throughput | no | yes |
GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAI14_HUMAN | [view interactions] | High throughput | no | yes |
LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
PACN3_HUMAN | [view interactions] | High throughput | no | yes |
AAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DSG2_HUMAN | [view interactions] | High throughput | no | no |
PARD3_HUMAN | [view interactions] | High throughput | no | yes |
TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GLI1_HUMAN | [view interactions] | High throughput | no | no |
TOX4_HUMAN | [view interactions] | High throughput | no | yes |
UBX2B_HUMAN | [view interactions] | High throughput | no | no |
DAA10_HUMAN | [view interactions] | High throughput | no | yes |
UBXN1_HUMAN | [view interactions] | High throughput | no | no |
ANTR1_HUMAN | [view interactions] | High throughput | no | no |
CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OXDA_HUMAN | [view interactions] | High throughput | no | no |
RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAD18_HUMAN | [view interactions] | High throughput | no | yes |
ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SFRP2_HUMAN | [view interactions] | High throughput | no | no |
IPP2_HUMAN | [view interactions] | High throughput | no | no |
SFRP1_HUMAN | [view interactions] | High throughput | no | no |
MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SFRP5_HUMAN | [view interactions] | High throughput | no | no |
PR15B_HUMAN | [view interactions] | High throughput | no | no |
CD2B2_HUMAN | [view interactions] | High throughput | no | yes |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
AHNK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PPP6_HUMAN | [view interactions] | High throughput | no | yes |
PP1R8_HUMAN | [view interactions] | High throughput | no | yes |
ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
YAF2_HUMAN | [view interactions] | High throughput | no | yes |
RBP56_HUMAN | [view interactions] | High throughput | no | yes |
ARMC8_HUMAN | [view interactions] | High throughput | no | yes |
CALL3_HUMAN | [view interactions] | High throughput | no | yes |
MATR3_HUMAN | [view interactions] | High throughput | no | yes |
SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PP1R7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MEP50_HUMAN | [view interactions] | High throughput | no | yes |
MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CHD3_HUMAN | [view interactions] | High throughput | no | yes |
ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CHD4_HUMAN | [view interactions] | High throughput | no | yes |
CDK2_HUMAN | [view interactions] | High throughput | no | yes |
ITA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FGF11_HUMAN | [view interactions] | High throughput | no | no |
IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
ASF1A_HUMAN | [view interactions] | High throughput | no | no |
LARP7_HUMAN | [view interactions] | High throughput | no | yes |
DEN2B_HUMAN | [view interactions] | High throughput | no | yes |
R144A_HUMAN | [view interactions] | High throughput | no | yes |
RHGBA_HUMAN | [view interactions] | High throughput | no | yes |
REST_HUMAN | [view interactions] | High throughput | no | yes |
KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H4_HUMAN | [view interactions] | High throughput | no | yes |
ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEK2_HUMAN | [view interactions] | High throughput | no | no |
MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRWD1_HUMAN | [view interactions] | High throughput | no | no |
RB12B_HUMAN | [view interactions] | High throughput | no | yes |
A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ABC3B_HUMAN | [view interactions] | High throughput | no | no |
BACH1_HUMAN | [view interactions] | High throughput | no | no |
COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZBT10_HUMAN | [view interactions] | High throughput | no | yes |
CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
YAP1_HUMAN | [view interactions] | High throughput | no | yes |
CDCA2_HUMAN | [view interactions] | High throughput | no | yes |
VRK3_HUMAN | [view interactions] | High throughput | no | yes |
PKHG3_HUMAN | [view interactions] | High throughput | no | yes |
TIA1_HUMAN | [view interactions] | High throughput | no | no |
ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANO7_HUMAN | [view interactions] | High throughput | no | no |
ZN106_HUMAN | [view interactions] | High throughput | no | no |
PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RGAP1_HUMAN | [view interactions] | High throughput | no | no |
WWP2_HUMAN | [view interactions] | High throughput | no | no |
SC16A_HUMAN | [view interactions] | High throughput | no | yes |
RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
K1671_HUMAN | [view interactions] | High throughput | no | yes |
RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCOA5_HUMAN | [view interactions] | High throughput | no | yes |
ECT2_HUMAN | [view interactions] | High throughput | no | no |
CYTSB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KI20A_HUMAN | [view interactions] | High throughput | no | yes |
COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PRC1_HUMAN | [view interactions] | High throughput | no | yes |
PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SSH2_HUMAN | [view interactions] | High throughput | no | no |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INS_HUMAN | [view interactions] | High throughput | no | no |
HNRH3_HUMAN | [view interactions] | High throughput | no | no |
NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
NUPR1_HUMAN | [view interactions] | High throughput | no | no |
P3C2A_HUMAN | [view interactions] | High throughput | no | yes |
NPC1_HUMAN | [view interactions] | High throughput | no | yes |
TPRN_HUMAN | [view interactions] | High throughput | no | yes |
BRD4_HUMAN | [view interactions] | High throughput | no | yes |
ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ILF3_HUMAN | [view interactions] | High throughput | no | yes |
TAF2_HUMAN | [view interactions] | High throughput | no | no |
RMP_HUMAN | [view interactions] | High throughput | no | yes |
ANDR_HUMAN | [view interactions] | High throughput | no | no |
EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ISG15_HUMAN | [view interactions] | High throughput | no | no |
ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FZR1_HUMAN | [view interactions] | High throughput | no | no |
ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WDR5_HUMAN | [view interactions] | High throughput | no | no |
PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
MYO5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGD5_HUMAN | [view interactions] | High throughput | no | yes |
AKAP2_HUMAN | [view interactions] | High throughput | no | no |
NALP7_HUMAN | [view interactions] | High throughput | no | no |
ACTC_HUMAN | [view interactions] | High throughput | no | no |
SIK2_HUMAN | [view interactions] | High throughput | no | yes |
COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SVIL_HUMAN | [view interactions] | High throughput | no | yes |
CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDRG1_HUMAN | [view interactions] | High throughput | no | yes |
SSRP1_HUMAN | [view interactions] | High throughput | no | yes |
MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TOP1_HUMAN | [view interactions] | High throughput | no | yes |
BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
UBX2A_HUMAN | [view interactions] | High throughput | no | no |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACTT1_HUMAN | [view interactions] | High throughput | no | no |
RIT1_HUMAN | [view interactions] | High throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLK1_HUMAN | [view interactions] | High throughput | no | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBX7_HUMAN | [view interactions] | High throughput | no | yes |
GA2L1_HUMAN | [view interactions] | High throughput | no | yes |
SAFB2_HUMAN | [view interactions] | High throughput | no | yes |
ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PAPOA_HUMAN | [view interactions] | High throughput | no | yes |
COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP1RB_HUMAN | [view interactions] | High throughput | no | yes |
HCFC1_HUMAN | [view interactions] | High throughput | no | yes |
WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KAT8_HUMAN | [view interactions] | High throughput | no | no |
DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DHX15_HUMAN | [view interactions] | High throughput | no | yes |
DAPK3_HUMAN | [view interactions] | High throughput | no | yes |
KIME_HUMAN | [view interactions] | High throughput | no | yes |
BACD2_HUMAN | [view interactions] | High throughput | no | no |
DENR_HUMAN | [view interactions] | High throughput | no | yes |
LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SIPA1_HUMAN | [view interactions] | High throughput | no | yes |
DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SAFB1_HUMAN | [view interactions] | High throughput | no | yes |
CPSF1_HUMAN | [view interactions] | High throughput | no | no |
INF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SSU72_HUMAN | [view interactions] | High throughput | no | yes |
RBMX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP37_HUMAN | [view interactions] | High throughput | no | no |
SI1L3_HUMAN | [view interactions] | High throughput | no | yes |
TRI14_HUMAN | [view interactions] | High throughput | no | yes |
MYO19_HUMAN | [view interactions] | High throughput | no | yes |
NECD_HUMAN | [view interactions] | High throughput | no | no |
ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN326_HUMAN | [view interactions] | High throughput | no | yes |
RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RMXL1_HUMAN | [view interactions] | High throughput | no | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PP16B_HUMAN | [view interactions] | High throughput | no | yes |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
PPR18_HUMAN | [view interactions] | High throughput | no | no |
PML_HUMAN | [view interactions] | High throughput | no | yes |
AAPK1_HUMAN | [view interactions] | High throughput | no | no |
AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
ECH1_HUMAN | [view interactions] | High throughput | no | yes |
XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRD16_HUMAN | [view interactions] | High throughput | no | no |
MECOM_HUMAN | [view interactions] | High throughput | no | yes |
ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
MOT11_HUMAN | [view interactions] | High throughput | no | no |
YLPM1_HUMAN | [view interactions] | High throughput | no | yes |
WDR82_HUMAN | [view interactions] | High throughput | no | no |
TARA_HUMAN | [view interactions] | High throughput | no | yes |
SHOC2_HUMAN | [view interactions] | High throughput | no | yes |
PLCL2_HUMAN | [view interactions] | High throughput | no | yes |
LRRC1_HUMAN | [view interactions] | High throughput | no | yes |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
CC85C_HUMAN | [view interactions] | High throughput | no | yes |
VCAM1_HUMAN | [view interactions] | High throughput | no | no |
TNFA_HUMAN | [view interactions] | High throughput | no | no |
TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MINP1_HUMAN | [view interactions] | High throughput | no | yes |
GYS1_HUMAN | [view interactions] | High throughput | no | yes |
PPR37_HUMAN | [view interactions] | High throughput | no | yes |
PPR3C_HUMAN | [view interactions] | High throughput | no | yes |
HTRA4_HUMAN | [view interactions] | High throughput | no | no |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NUAK1_HUMAN | [view interactions] | High throughput | no | no |
NUAK2_HUMAN | [view interactions] | High throughput | no | yes |
LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
TMM33_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
JUN_HUMAN | [view interactions] | High throughput | no | yes |
PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAV3_HUMAN | [view interactions] | High throughput | no | no |
LITD1_HUMAN | [view interactions] | High throughput | no | no |
CSRN2_HUMAN | [view interactions] | High throughput | no | yes |
IPP2B_HUMAN | [view interactions] | High throughput | no | no |
CSRN1_HUMAN | [view interactions] | High throughput | no | no |
IPP2C_HUMAN | [view interactions] | High throughput | no | no |
CRTP1_HUMAN | [view interactions] | High throughput | no | yes |
KANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PPR27_HUMAN | [view interactions] | High throughput | no | no |
PHAR3_HUMAN | [view interactions] | High throughput | no | no |
NRAC_HUMAN | [view interactions] | High throughput | no | no |
MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
LMTK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEMO_HUMAN | [view interactions] | High throughput | no | yes |
RIPK3_HUMAN | [view interactions] | High throughput | no | no |
CEP72_HUMAN | [view interactions] | High throughput | no | yes |
SAS6_HUMAN | [view interactions] | High throughput | no | no |
CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMAD6_HUMAN | [view interactions] | High throughput | no | no |
RAB21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UXT_HUMAN | [view interactions] | High throughput | no | yes |
PQBP1_HUMAN | [view interactions] | High throughput | no | yes |
TLK1_HUMAN | [view interactions] | High throughput | no | yes |
CT027_HUMAN | [view interactions] | High throughput | no | yes |
RPAP3_HUMAN | [view interactions] | High throughput | no | yes |
RPAB1_HUMAN | [view interactions] | High throughput | no | yes |
WBP11_HUMAN | [view interactions] | High throughput | no | yes |
HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
PPR3B_HUMAN | [view interactions] | High throughput | no | yes |
PCNA_HUMAN | [view interactions] | High throughput | no | no |
CCND3_HUMAN | [view interactions] | High throughput | no | no |
MAX_HUMAN | [view interactions] | High throughput | no | yes |
BCL2_HUMAN | [view interactions] | High throughput | no | no |
UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
CCND1_HUMAN | [view interactions] | High throughput | no | yes |
MED23_HUMAN | [view interactions] | High throughput | no | no |
PACS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INTU_HUMAN | [view interactions] | High throughput | no | yes |
DEC1_HUMAN | [view interactions] | High throughput | no | no |
MEOX2_HUMAN | [view interactions] | High throughput | no | no |
SPC1L_HUMAN | [view interactions] | High throughput | no | no |
SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
AKA11_HUMAN | [view interactions] | High throughput | no | yes |
ZFYV9_HUMAN | [view interactions] | High throughput | no | yes |
PP16A_HUMAN | [view interactions] | High throughput | no | no |
CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INT1_HUMAN | [view interactions] | High throughput | no | yes |
BHE40_HUMAN | [view interactions] | High throughput | no | yes |
INT6_HUMAN | [view interactions] | High throughput | no | yes |
CLOCK_HUMAN | [view interactions] | High throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RORG_HUMAN | [view interactions] | High throughput | no | no |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DUX4C_HUMAN | [view interactions] | High throughput | no | no |
SIR7_HUMAN | [view interactions] | High throughput | no | yes |
P5F1B_HUMAN | [view interactions] | High throughput | no | no |
TRPM8_HUMAN | [view interactions] | Computational | no | no |
ML12A_HUMAN | [view interactions] | Computational | no | no |
FIP1_HUMAN | [view interactions] | Computational | no | yes |
PP4R2_HUMAN | [view interactions] | Computational | no | yes |
2A5A_HUMAN | [view interactions] | Computational | no | yes |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KC1E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
WDR33_HUMAN | [view interactions] | Computational | no | yes |
NEPR1_HUMAN | [view interactions] | Computational | no | yes |
PER2_HUMAN | [view interactions] | Computational | no | yes |
PLK1_HUMAN | [view interactions] | Computational | no | yes |
2ABA_HUMAN | [view interactions] | Computational | no | yes |
PPR3E_HUMAN | [view interactions] | Computational | no | yes |
2ABD_HUMAN | [view interactions] | Computational | no | yes |
KGP1_HUMAN | [view interactions] | Computational | no | yes |
KPCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CPSF2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RBBP6_HUMAN | [view interactions] | Computational | no | yes |
PP2BB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PPLA_HUMAN | [view interactions] | Computational | no | no |
PP4R4_HUMAN | [view interactions] | Computational | no | yes |
CANB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CPSF4_HUMAN | [view interactions] | Computational | no | yes |
CNEP1_HUMAN | [view interactions] | Computational | no | yes |
MYH11_HUMAN | [view entry] [view interactions] | Computational | yes | no |
KCC2B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CPSF3_HUMAN | [view interactions] | Computational | no | yes |
PPR3F_HUMAN | [view interactions] | Computational | no | yes |
PPR1A_HUMAN | [view interactions] | Computational | no | yes |
RHOC_HUMAN | [view interactions] | Computational | no | no |
GYS2_HUMAN | [view interactions] | Computational | no | no |
PTPA_HUMAN | [view interactions] | Computational | no | yes |
IF2A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
1433B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PP4R1_HUMAN | [view interactions] | Computational | no | yes |
PP2AB_HUMAN | [view interactions] | Computational | no | yes |
CYC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KC1D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SYMPK_HUMAN | [view interactions] | Computational | no | yes |
ROCK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PHAR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ROCK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PPR3D_HUMAN | [view interactions] | Computational | no | yes |
ML12B_HUMAN | [view interactions] | Computational | no | no |
NMDE1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MPIP3_HUMAN | [view interactions] | Computational | no | yes |
CAC1C_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PLIN1_HUMAN | [view interactions] | Computational | no | no |
RBL1_HUMAN | [view interactions] | Computational | no | yes |
RAF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CAC1D_HUMAN | [view interactions] | Computational | no | yes |
WWTR1_HUMAN | [view interactions] | Computational | no | yes |
PPR1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MYL9_HUMAN | [view interactions] | Computational | no | no |
PP14A_HUMAN | [view interactions] | Computational | no | yes |
KGP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RBL2_HUMAN | [view interactions] | Computational | no | yes |
NMDE2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PP2BA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RASF5_HUMAN | [view interactions] | Computational | no | yes |
CRY1_HUMAN | [view interactions] | Computational | no | yes |
KCC2D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PER1_HUMAN | [view interactions] | Computational | no | no |
PP2AA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
2AAA_HUMAN | [view entry] [view interactions] | Computational | yes | no |