LMTK2_HUMAN
Evidence for PS localization
Functions
Phosphorylates PPP1C, phosphorylase b and CFTR. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in LMTK2_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 37.7778 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 37.7778 | 5 | yes |
| GO:0043168 | anion binding | 37.7778 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 35.5556 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 35.5556 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 28.8889 | 6 | yes |
| GO:0005524 | ATP binding | 26.6667 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 26.6667 | 5 | yes |
| GO:0019900 | kinase binding | 24.4444 | 4 | no |
| GO:0019901 | protein kinase binding | 24.4444 | 5 | no |
| GO:0003723 | RNA binding | 24.4444 | 4 | no |
| GO:0016301 | kinase activity | 13.3333 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 13.3333 | 4 | yes |
| GO:0019888 | protein phosphatase regulator activity | 13.3333 | 4 | yes |
| GO:0017022 | myosin binding | 11.1111 | 4 | yes |
| GO:0004674 | protein serine/threonine kinase activity | 8.8889 | 4 | yes |
| GO:0106310 | protein serine kinase activity | 8.8889 | 4 | yes |
| GO:0004864 | protein phosphatase inhibitor activity | 4.4444 | 5 | yes |
| GO:0019212 | phosphatase inhibitor activity | 4.4444 | 4 | yes |
| GO:0070853 | myosin VI binding | 4.4444 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in LMTK2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 68.8889 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 60.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 57.7778 | 4 | no |
| GO:0010646 | regulation of cell communication | 51.1111 | 4 | no |
| GO:0008104 | protein localization | 48.8889 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 48.8889 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 46.6667 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 42.2222 | 4 | no |
| GO:0009966 | regulation of signal transduction | 42.2222 | 4 | no |
| GO:0051049 | regulation of transport | 42.2222 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 42.2222 | 5 | no |
| GO:0071702 | organic substance transport | 40.0000 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 40.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 40.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 40.0000 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 40.0000 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 40.0000 | 4 | no |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0071705 | nitrogen compound transport | 37.7778 | 4 | yes |
| GO:0036211 | protein modification process | 35.5556 | 4 | yes |
| GO:0043412 | macromolecule modification | 35.5556 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 35.5556 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 35.5556 | 5 | no |
| GO:0023056 | positive regulation of signaling | 35.5556 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 35.5556 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 33.3333 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 33.3333 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
| GO:0015031 | protein transport | 31.1111 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 31.1111 | 6 | no |
| GO:0045595 | regulation of cell differentiation | 28.8889 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 28.8889 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 28.8889 | 6 | no |
| GO:0051094 | positive regulation of developmental process | 26.6667 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.6667 | 6 | no |
| GO:0071310 | cellular response to organic substance | 26.6667 | 4 | no |
| GO:0022607 | cellular component assembly | 26.6667 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.4444 | 6 | no |
| GO:0031400 | negative regulation of protein modification process | 24.4444 | 7 | no |
| GO:0042981 | regulation of apoptotic process | 24.4444 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 24.4444 | 4 | no |
| GO:0050776 | regulation of immune response | 24.4444 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.4444 | 5 | no |
| GO:2000026 | regulation of multicellular organismal development | 24.4444 | 4 | no |
| GO:0002684 | positive regulation of immune system process | 22.2222 | 4 | no |
| GO:0023057 | negative regulation of signaling | 22.2222 | 4 | no |
| GO:0045597 | positive regulation of cell differentiation | 22.2222 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 22.2222 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.2222 | 7 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.2222 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.2222 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.2222 | 6 | no |
| GO:0051726 | regulation of cell cycle | 22.2222 | 4 | no |
| GO:0060341 | regulation of cellular localization | 22.2222 | 4 | no |
| GO:0006468 | protein phosphorylation | 15.5556 | 5 | yes |
| GO:0016310 | phosphorylation | 15.5556 | 5 | yes |
| GO:0018193 | peptidyl-amino acid modification | 15.5556 | 5 | yes |
| GO:0006811 | monoatomic ion transport | 13.3333 | 4 | yes |
| GO:0006812 | monoatomic cation transport | 11.1111 | 5 | yes |
| GO:0030001 | metal ion transport | 11.1111 | 6 | yes |
| GO:0018105 | peptidyl-serine phosphorylation | 8.8889 | 6 | yes |
| GO:0018107 | peptidyl-threonine phosphorylation | 8.8889 | 6 | yes |
| GO:0018209 | peptidyl-serine modification | 8.8889 | 6 | yes |
| GO:0018210 | peptidyl-threonine modification | 8.8889 | 6 | yes |
| GO:0043112 | receptor metabolic process | 8.8889 | 4 | yes |
| GO:0046777 | protein autophosphorylation | 8.8889 | 6 | yes |
| GO:0001881 | receptor recycling | 6.6667 | 5 | yes |
| GO:0032456 | endocytic recycling | 6.6667 | 4 | yes |
| GO:0098927 | vesicle-mediated transport between endosomal compartments | 6.6667 | 4 | yes |
| GO:0000041 | transition metal ion transport | 4.4444 | 7 | yes |
| GO:0006826 | iron ion transport | 4.4444 | 8 | yes |
| GO:0033572 | transferrin transport | 4.4444 | 5 | yes |
| GO:0045022 | early endosome to late endosome transport | 4.4444 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LMTK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IPP2_HUMAN | [view interactions] | Low throughput | no | no |
| MYO6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| DEN6A_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| COR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SORT_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| CC113_HUMAN | [view interactions] | High throughput | no | no |
| HUTH_HUMAN | [view interactions] | High throughput | no | yes |
| INVS_HUMAN | [view interactions] | High throughput | no | no |
| ATD3B_HUMAN | [view interactions] | High throughput | no | yes |
| TAD2B_HUMAN | [view interactions] | High throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPM1F_HUMAN | [view interactions] | High throughput | no | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1K_HUMAN | [view interactions] | High throughput | no | yes |
| ILKAP_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
| PTN6_HUMAN | [view interactions] | High throughput | no | no |
| DUS6_HUMAN | [view interactions] | High throughput | no | yes |
| DUS14_HUMAN | [view interactions] | High throughput | no | yes |
| PTN12_HUMAN | [view interactions] | High throughput | no | yes |
| DUS29_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR6_HUMAN | [view interactions] | High throughput | no | no |
| TPTE2_HUMAN | [view interactions] | High throughput | no | no |
| PTPC1_HUMAN | [view interactions] | High throughput | no | yes |
| CC14A_HUMAN | [view interactions] | High throughput | no | yes |
| STYX_HUMAN | [view interactions] | High throughput | no | yes |
| DUS19_HUMAN | [view interactions] | High throughput | no | yes |
| MPIP3_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| RS29_HUMAN | [view interactions] | High throughput | no | yes |
| RAB6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YTDC1_HUMAN | [view interactions] | High throughput | no | yes |
| CCD86_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| XPO5_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STML2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P5CR2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRL2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC9_HUMAN | [view interactions] | High throughput | no | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DD19A_HUMAN | [view interactions] | High throughput | no | yes |
| RAB1C_HUMAN | [view interactions] | High throughput | no | no |
| NUP93_HUMAN | [view interactions] | High throughput | no | yes |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1R7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| SP16H_HUMAN | [view interactions] | High throughput | no | yes |
| CNBP_HUMAN | [view interactions] | High throughput | no | no |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| IF2B_HUMAN | [view interactions] | High throughput | no | yes |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
| EBP2_HUMAN | [view interactions] | High throughput | no | yes |
| SYK_HUMAN | [view interactions] | High throughput | no | yes |
| H2AY_HUMAN | [view interactions] | High throughput | no | yes |
| KIF5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLC4_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPR3A_HUMAN | [view interactions] | High throughput | no | no |
| LYPL1_HUMAN | [view interactions] | High throughput | no | yes |
| NPT2B_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ATP9A_HUMAN | [view interactions] | High throughput | no | yes |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |