LMTK2_HUMAN
Phosphorylates PPP1C, phosphorylase b and CFTR. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in LMTK2_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 35.1351 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 35.1351 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 35.1351 | 4 | yes |
GO:0005524 | ATP binding | 27.0270 | 5 | yes |
GO:0030554 | adenyl nucleotide binding | 27.0270 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 27.0270 | 5 | yes |
GO:0019900 | kinase binding | 24.3243 | 4 | no |
GO:0019901 | protein kinase binding | 24.3243 | 5 | no |
GO:0046872 | metal ion binding | 21.6216 | 4 | no |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 16.2162 | 4 | yes |
GO:0016301 | kinase activity | 16.2162 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 16.2162 | 4 | yes |
GO:0019888 | protein phosphatase regulator activity | 16.2162 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 10.8108 | 4 | yes |
GO:0017022 | myosin binding | 10.8108 | 4 | yes |
GO:0106310 | protein serine kinase activity | 10.8108 | 4 | yes |
GO:0004864 | protein phosphatase inhibitor activity | 5.4054 | 5 | yes |
GO:0019212 | phosphatase inhibitor activity | 5.4054 | 4 | yes |
GO:0070853 | myosin VI binding | 5.4054 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in LMTK2_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 72.9730 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 62.1622 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 59.4595 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 56.7568 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 51.3514 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 51.3514 | 4 | no |
GO:0008104 | protein localization | 48.6486 | 4 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 45.9459 | 5 | yes |
GO:0036211 | protein modification process | 45.9459 | 4 | yes |
GO:0043412 | macromolecule modification | 45.9459 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 45.9459 | 5 | no |
GO:0010646 | regulation of cell communication | 43.2432 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 43.2432 | 5 | no |
GO:0006796 | phosphate-containing compound metabolic process | 40.5405 | 4 | yes |
GO:0071702 | organic substance transport | 40.5405 | 4 | yes |
GO:0010468 | regulation of gene expression | 40.5405 | 5 | no |
GO:0051049 | regulation of transport | 40.5405 | 4 | no |
GO:0006996 | organelle organization | 40.5405 | 4 | no |
GO:0071705 | nitrogen compound transport | 37.8378 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 37.8378 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 37.8378 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 35.1351 | 6 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 35.1351 | 5 | yes |
GO:0051128 | regulation of cellular component organization | 35.1351 | 4 | no |
GO:0009966 | regulation of signal transduction | 32.4324 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 32.4324 | 4 | no |
GO:0015031 | protein transport | 29.7297 | 4 | yes |
GO:0016192 | vesicle-mediated transport | 29.7297 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 29.7297 | 5 | no |
GO:0023056 | positive regulation of signaling | 29.7297 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 29.7297 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 29.7297 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 29.7297 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 29.7297 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 29.7297 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 29.7297 | 6 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 27.0270 | 6 | yes |
GO:0042325 | regulation of phosphorylation | 27.0270 | 7 | yes |
GO:0043085 | positive regulation of catalytic activity | 27.0270 | 4 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 27.0270 | 7 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 27.0270 | 5 | no |
GO:0031399 | regulation of protein modification process | 27.0270 | 6 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.0270 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 27.0270 | 5 | no |
GO:0006468 | protein phosphorylation | 24.3243 | 5 | yes |
GO:0006811 | ion transport | 24.3243 | 4 | yes |
GO:0016310 | phosphorylation | 24.3243 | 5 | yes |
GO:0030030 | cell projection organization | 24.3243 | 4 | yes |
GO:0051338 | regulation of transferase activity | 24.3243 | 4 | yes |
GO:0045595 | regulation of cell differentiation | 24.3243 | 4 | no |
GO:0051094 | positive regulation of developmental process | 24.3243 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 24.3243 | 4 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.3243 | 5 | no |
GO:0022607 | cellular component assembly | 24.3243 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 24.3243 | 5 | no |
GO:0018193 | peptidyl-amino acid modification | 21.6216 | 5 | yes |
GO:0042327 | positive regulation of phosphorylation | 21.6216 | 8 | yes |
GO:0043549 | regulation of kinase activity | 21.6216 | 5 | yes |
GO:0051347 | positive regulation of transferase activity | 21.6216 | 5 | yes |
GO:0071310 | cellular response to organic substance | 21.6216 | 4 | no |
GO:0006355 | regulation of DNA-templated transcription | 21.6216 | 6 | no |
GO:0051252 | regulation of RNA metabolic process | 21.6216 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 21.6216 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 21.6216 | 6 | no |
GO:0001932 | regulation of protein phosphorylation | 21.6216 | 7 | no |
GO:0051248 | negative regulation of protein metabolic process | 21.6216 | 6 | no |
GO:0031401 | positive regulation of protein modification process | 21.6216 | 7 | no |
GO:0050776 | regulation of immune response | 21.6216 | 4 | no |
GO:0010941 | regulation of cell death | 21.6216 | 4 | no |
GO:0010942 | positive regulation of cell death | 21.6216 | 5 | no |
GO:0042981 | regulation of apoptotic process | 21.6216 | 6 | no |
GO:0043067 | regulation of programmed cell death | 21.6216 | 5 | no |
GO:0006812 | cation transport | 18.9189 | 5 | yes |
GO:0033674 | positive regulation of kinase activity | 18.9189 | 6 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 16.2162 | 4 | yes |
GO:0016197 | endosomal transport | 16.2162 | 4 | yes |
GO:0030001 | metal ion transport | 16.2162 | 6 | yes |
GO:0046777 | protein autophosphorylation | 16.2162 | 6 | yes |
GO:0018209 | peptidyl-serine modification | 13.5135 | 6 | yes |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 10.8108 | 5 | yes |
GO:0007409 | axonogenesis | 10.8108 | 8 | yes |
GO:0016482 | cytosolic transport | 10.8108 | 4 | yes |
GO:0018105 | peptidyl-serine phosphorylation | 10.8108 | 6 | yes |
GO:0018107 | peptidyl-threonine phosphorylation | 10.8108 | 6 | yes |
GO:0018210 | peptidyl-threonine modification | 10.8108 | 6 | yes |
GO:0032990 | cell part morphogenesis | 10.8108 | 4 | yes |
GO:0048812 | neuron projection morphogenesis | 10.8108 | 7 | yes |
GO:0048858 | cell projection morphogenesis | 10.8108 | 5 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 10.8108 | 6 | yes |
GO:0032456 | endocytic recycling | 8.1081 | 5 | yes |
GO:0043112 | receptor metabolic process | 8.1081 | 4 | yes |
GO:0098876 | vesicle-mediated transport to the plasma membrane | 8.1081 | 4 | yes |
GO:0000041 | transition metal ion transport | 5.4054 | 7 | yes |
GO:0001881 | receptor recycling | 5.4054 | 5 | yes |
GO:0006826 | iron ion transport | 5.4054 | 8 | yes |
GO:0033572 | transferrin transport | 5.4054 | 5 | yes |
GO:0045022 | early endosome to late endosome transport | 5.4054 | 5 | yes |
GO:0098927 | vesicle-mediated transport between endosomal compartments | 5.4054 | 5 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in LMTK2_HUMAN |
---|---|---|---|---|
DOID:0050700 | cardiomyopathy | 5.4054 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 5.4054 | 5 | no |
DOID:114 | heart disease | 5.4054 | 3 | no |
DOID:2843 | long QT syndrome | 5.4054 | 6 | no |
DOID:0111962 | combined immunodeficiency | 5.4054 | 4 | no |
DOID:612 | primary immunodeficiency disease | 5.4054 | 3 | no |
DOID:627 | severe combined immunodeficiency | 5.4054 | 5 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LMTK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IPP2_HUMAN | [view interactions] | Low throughput | no | no |
MYO6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P5CR2_HUMAN | [view interactions] | High throughput | no | yes |
STML2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
XPO5_HUMAN | [view interactions] | High throughput | no | yes |
ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
CCD86_HUMAN | [view interactions] | High throughput | no | yes |
YTDC1_HUMAN | [view interactions] | High throughput | no | yes |
RAB6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS29_HUMAN | [view interactions] | High throughput | no | yes |
FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
PPR3A_HUMAN | [view interactions] | High throughput | no | no |
LYPL1_HUMAN | [view interactions] | High throughput | no | yes |
NPT2B_HUMAN | [view interactions] | High throughput | no | no |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
ATP9A_HUMAN | [view interactions] | High throughput | no | yes |
SIR6_HUMAN | [view interactions] | High throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
DEN6A_HUMAN | [view interactions] | High throughput | no | yes |
FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
OCLN_HUMAN | [view interactions] | High throughput | no | no |
PEX14_HUMAN | [view interactions] | High throughput | no | yes |
RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
STX6_HUMAN | [view interactions] | High throughput | no | yes |
STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SORT_HUMAN | [view interactions] | High throughput | no | yes |
MECOM_HUMAN | [view interactions] | High throughput | no | yes |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TAD2B_HUMAN | [view interactions] | High throughput | no | yes |
ATD3B_HUMAN | [view interactions] | High throughput | no | yes |
INVS_HUMAN | [view interactions] | High throughput | no | no |
HUTH_HUMAN | [view interactions] | High throughput | no | yes |
CC113_HUMAN | [view interactions] | High throughput | no | no |
PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PPM1F_HUMAN | [view interactions] | High throughput | no | yes |
PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DUS14_HUMAN | [view interactions] | High throughput | no | yes |
DUS6_HUMAN | [view interactions] | High throughput | no | yes |
PTN12_HUMAN | [view interactions] | High throughput | no | yes |
PTN6_HUMAN | [view interactions] | High throughput | no | no |
PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
PPM1K_HUMAN | [view interactions] | High throughput | no | yes |
ILKAP_HUMAN | [view interactions] | High throughput | no | yes |
STYX_HUMAN | [view interactions] | High throughput | no | yes |
DUS19_HUMAN | [view interactions] | High throughput | no | yes |
DUS29_HUMAN | [view interactions] | High throughput | no | yes |
CC14A_HUMAN | [view interactions] | High throughput | no | yes |
PTPC1_HUMAN | [view interactions] | High throughput | no | yes |
TPTE2_HUMAN | [view interactions] | High throughput | no | no |
MTMR6_HUMAN | [view interactions] | High throughput | no | no |
MPIP3_HUMAN | [view interactions] | High throughput | no | yes |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DHX9_HUMAN | [view interactions] | High throughput | no | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KLC4_HUMAN | [view interactions] | High throughput | no | yes |
KIF5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H2AY_HUMAN | [view interactions] | High throughput | no | yes |
SYK_HUMAN | [view interactions] | High throughput | no | yes |
EBP2_HUMAN | [view interactions] | High throughput | no | yes |
NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EMD_HUMAN | [view interactions] | High throughput | no | yes |
IF2B_HUMAN | [view interactions] | High throughput | no | yes |
RBM14_HUMAN | [view interactions] | High throughput | no | yes |
UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CNBP_HUMAN | [view interactions] | High throughput | no | no |
SP16H_HUMAN | [view interactions] | High throughput | no | yes |
SSRP1_HUMAN | [view interactions] | High throughput | no | yes |
PP1R7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NUP93_HUMAN | [view interactions] | High throughput | no | yes |
RAB1C_HUMAN | [view interactions] | High throughput | no | no |
DD19A_HUMAN | [view interactions] | High throughput | no | yes |
M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJC9_HUMAN | [view interactions] | High throughput | no | yes |
HNRL2_HUMAN | [view interactions] | High throughput | no | yes |