Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

COR1A_HUMAN

GO
G2C
SynGO

May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in COR1A_HUMAN
GO:0003779 actin binding 36.0000 4 yes
GO:0045296 cadherin binding 26.0000 4 no
GO:0003723 RNA binding 24.0000 4 yes
GO:0019900 kinase binding 22.0000 4 no
GO:0042803 protein homodimerization activity 12.0000 4 yes
GO:0017022 myosin binding 6.0000 4 yes
GO:0003785 actin monomer binding 4.0000 5 yes
GO:0032036 myosin heavy chain binding 4.0000 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in COR1A_HUMAN
GO:0048522 positive regulation of cellular process 58.0000 4 yes
GO:0006996 organelle organization 50.0000 4 yes
GO:0022607 cellular component assembly 48.0000 4 yes
GO:0051128 regulation of cellular component organization 46.0000 4 yes
GO:0048523 negative regulation of cellular process 44.0000 4 yes
GO:0031323 regulation of cellular metabolic process 42.0000 4 no
GO:0044087 regulation of cellular component biogenesis 40.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 40.0000 4 no
GO:0080090 regulation of primary metabolic process 38.0000 4 no
GO:0010646 regulation of cell communication 34.0000 4 no
GO:0007010 cytoskeleton organization 32.0000 5 yes
GO:0009889 regulation of biosynthetic process 32.0000 4 no
GO:0097435 supramolecular fiber organization 30.0000 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 30.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 30.0000 5 no
GO:0051130 positive regulation of cellular component organization 30.0000 5 no
GO:0030030 cell projection organization 28.0000 4 yes
GO:0033043 regulation of organelle organization 28.0000 5 yes
GO:0009893 positive regulation of metabolic process 28.0000 4 no
GO:0009966 regulation of signal transduction 28.0000 4 no
GO:0120036 plasma membrane bounded cell projection organization 26.0000 5 yes
GO:0010468 regulation of gene expression 26.0000 6 no
GO:0031325 positive regulation of cellular metabolic process 26.0000 5 no
GO:0008104 protein localization 26.0000 4 no
GO:0036211 protein modification process 26.0000 4 no
GO:0043412 macromolecule modification 26.0000 4 no
GO:0051246 regulation of protein metabolic process 26.0000 5 no
GO:0007015 actin filament organization 24.0000 5 yes
GO:0022603 regulation of anatomical structure morphogenesis 24.0000 4 yes
GO:0051493 regulation of cytoskeleton organization 24.0000 6 yes
GO:1902903 regulation of supramolecular fiber organization 24.0000 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 24.0000 5 no
GO:0031344 regulation of cell projection organization 24.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 24.0000 6 no
GO:0009894 regulation of catabolic process 24.0000 4 no
GO:0043933 protein-containing complex organization 24.0000 4 no
GO:0042981 regulation of apoptotic process 22.0000 5 yes
GO:0043067 regulation of programmed cell death 22.0000 4 yes
GO:0071310 cellular response to organic substance 22.0000 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.0000 5 no
GO:0048584 positive regulation of response to stimulus 22.0000 4 no
GO:0032956 regulation of actin cytoskeleton organization 20.0000 5 yes
GO:0032970 regulation of actin filament-based process 20.0000 4 yes
GO:0043254 regulation of protein-containing complex assembly 20.0000 5 yes
GO:0051129 negative regulation of cellular component organization 20.0000 5 yes
GO:0051240 positive regulation of multicellular organismal process 20.0000 4 yes
GO:0070925 organelle assembly 20.0000 5 yes
GO:0098657 import into cell 20.0000 4 yes
GO:0051049 regulation of transport 18.0000 4 yes
GO:0110053 regulation of actin filament organization 18.0000 6 yes
GO:0022604 regulation of cell morphogenesis 16.0000 5 yes
GO:0030334 regulation of cell migration 16.0000 5 yes
GO:0034097 response to cytokine 16.0000 4 yes
GO:0042127 regulation of cell population proliferation 16.0000 4 yes
GO:0061024 membrane organization 16.0000 4 yes
GO:2000145 regulation of cell motility 16.0000 4 yes
GO:0002684 positive regulation of immune system process 14.0000 4 yes
GO:0010639 negative regulation of organelle organization 14.0000 6 yes
GO:0032271 regulation of protein polymerization 14.0000 6 yes
GO:0071345 cellular response to cytokine stimulus 14.0000 5 yes
GO:0001667 ameboidal-type cell migration 12.0000 4 yes
GO:0008284 positive regulation of cell population proliferation 12.0000 5 yes
GO:0030155 regulation of cell adhesion 12.0000 4 yes
GO:0030335 positive regulation of cell migration 12.0000 6 yes
GO:0032535 regulation of cellular component size 12.0000 4 yes
GO:0040017 positive regulation of locomotion 12.0000 4 yes
GO:0043066 negative regulation of apoptotic process 12.0000 6 yes
GO:0043069 negative regulation of programmed cell death 12.0000 5 yes
GO:0043523 regulation of neuron apoptotic process 12.0000 6 yes
GO:0051494 negative regulation of cytoskeleton organization 12.0000 7 yes
GO:0060627 regulation of vesicle-mediated transport 12.0000 4 yes
GO:1902904 negative regulation of supramolecular fiber organization 12.0000 6 yes
GO:2000147 positive regulation of cell motility 12.0000 5 yes
GO:0006915 apoptotic process 10.0000 4 yes
GO:0008064 regulation of actin polymerization or depolymerization 10.0000 6 yes
GO:0016050 vesicle organization 10.0000 5 yes
GO:0030832 regulation of actin filament length 10.0000 5 yes
GO:0030833 regulation of actin filament polymerization 10.0000 7 yes
GO:0045785 positive regulation of cell adhesion 10.0000 5 yes
GO:0140546 defense response to symbiont 10.0000 4 yes
GO:0022407 regulation of cell-cell adhesion 8.0000 5 yes
GO:0022409 positive regulation of cell-cell adhesion 8.0000 6 yes
GO:0034762 regulation of transmembrane transport 8.0000 4 yes
GO:0043524 negative regulation of neuron apoptotic process 8.0000 7 yes
GO:0051402 neuron apoptotic process 8.0000 5 yes
GO:0060326 cell chemotaxis 8.0000 4 yes
GO:0061025 membrane fusion 8.0000 5 yes
GO:0001894 tissue homeostasis 6.0000 4 yes
GO:0002685 regulation of leukocyte migration 6.0000 4 yes
GO:0002687 positive regulation of leukocyte migration 6.0000 5 yes
GO:0002694 regulation of leukocyte activation 6.0000 4 yes
GO:0002696 positive regulation of leukocyte activation 6.0000 5 yes
GO:0006811 monoatomic ion transport 6.0000 4 yes
GO:0006812 monoatomic cation transport 6.0000 5 yes
GO:0006906 vesicle fusion 6.0000 6 yes
GO:0006909 phagocytosis 6.0000 4 yes
GO:0007033 vacuole organization 6.0000 5 yes
GO:0010631 epithelial cell migration 6.0000 5 yes
GO:0030001 metal ion transport 6.0000 6 yes
GO:0031338 regulation of vesicle fusion 6.0000 5 yes
GO:0045055 regulated exocytosis 6.0000 4 yes
GO:0046903 secretion 6.0000 4 yes
GO:0048284 organelle fusion 6.0000 5 yes
GO:0050863 regulation of T cell activation 6.0000 6 yes
GO:0050865 regulation of cell activation 6.0000 4 yes
GO:0050867 positive regulation of cell activation 6.0000 5 yes
GO:0050870 positive regulation of T cell activation 6.0000 7 yes
GO:0051051 negative regulation of transport 6.0000 4 yes
GO:0051125 regulation of actin nucleation 6.0000 7 yes
GO:0051126 negative regulation of actin nucleation 6.0000 7 yes
GO:0051249 regulation of lymphocyte activation 6.0000 5 yes
GO:0051251 positive regulation of lymphocyte activation 6.0000 6 yes
GO:0071675 regulation of mononuclear cell migration 6.0000 5 yes
GO:0071677 positive regulation of mononuclear cell migration 6.0000 6 yes
GO:0072676 lymphocyte migration 6.0000 4 yes
GO:0072678 T cell migration 6.0000 5 yes
GO:0090174 organelle membrane fusion 6.0000 6 yes
GO:0098927 vesicle-mediated transport between endosomal compartments 6.0000 4 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 6.0000 6 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 6.0000 7 yes
GO:2000401 regulation of lymphocyte migration 6.0000 6 yes
GO:2000403 positive regulation of lymphocyte migration 6.0000 7 yes
GO:2000404 regulation of T cell migration 6.0000 7 yes
GO:2000406 positive regulation of T cell migration 6.0000 8 yes
GO:0001845 phagolysosome assembly 4.0000 6 yes
GO:0006816 calcium ion transport 4.0000 7 yes
GO:0007040 lysosome organization 4.0000 7 yes
GO:0010959 regulation of metal ion transport 4.0000 6 yes
GO:0031339 negative regulation of vesicle fusion 4.0000 5 yes
GO:0032796 uropod organization 4.0000 6 yes
GO:0032943 mononuclear cell proliferation 4.0000 4 yes
GO:0032944 regulation of mononuclear cell proliferation 4.0000 6 yes
GO:0032946 positive regulation of mononuclear cell proliferation 4.0000 7 yes
GO:0034765 regulation of monoatomic ion transmembrane transport 4.0000 5 yes
GO:0038179 neurotrophin signaling pathway 4.0000 4 yes
GO:0038180 nerve growth factor signaling pathway 4.0000 5 yes
GO:0042098 T cell proliferation 4.0000 5 yes
GO:0042102 positive regulation of T cell proliferation 4.0000 8 yes
GO:0042110 T cell activation 4.0000 4 yes
GO:0042129 regulation of T cell proliferation 4.0000 7 yes
GO:0043029 T cell homeostasis 4.0000 4 yes
GO:0043269 regulation of monoatomic ion transport 4.0000 5 yes
GO:0043320 natural killer cell degranulation 4.0000 4 yes
GO:0046651 lymphocyte proliferation 4.0000 4 yes
GO:0048873 homeostasis of number of cells within a tissue 4.0000 4 yes
GO:0050670 regulation of lymphocyte proliferation 4.0000 6 yes
GO:0050671 positive regulation of lymphocyte proliferation 4.0000 7 yes
GO:0050918 positive chemotaxis 4.0000 4 yes
GO:0051279 regulation of release of sequestered calcium ion into cytosol 4.0000 5 yes
GO:0051282 regulation of sequestering of calcium ion 4.0000 4 yes
GO:0051924 regulation of calcium ion transport 4.0000 7 yes
GO:0061502 early endosome to recycling endosome transport 4.0000 5 yes
GO:0070663 regulation of leukocyte proliferation 4.0000 5 yes
GO:0070665 positive regulation of leukocyte proliferation 4.0000 6 yes
GO:0070670 response to interleukin-4 4.0000 5 yes
GO:0071353 cellular response to interleukin-4 4.0000 6 yes
GO:0072679 thymocyte migration 4.0000 6 yes
GO:0080171 lytic vacuole organization 4.0000 6 yes
GO:1903169 regulation of calcium ion transmembrane transport 4.0000 7 yes
GO:1904062 regulation of monoatomic cation transmembrane transport 4.0000 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CD5R1_HUMAN [view entry] [view interactions] Low throughput yes no
CAPZB_HUMAN [view entry] [view interactions] Low throughput yes yes
WDR26_HUMAN [view interactions] Low throughput no yes
COR1A_HUMAN [view entry] [view interactions] Low throughput yes no
NACAM_HUMAN [view interactions] High throughput no no
NSF1C_HUMAN [view entry] [view interactions] High throughput yes yes
PALMD_HUMAN [view interactions] High throughput no no
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD4_HUMAN [view interactions] High throughput no yes
KS6C1_HUMAN [view entry] [view interactions] High throughput yes no
SRBS1_HUMAN [view entry] [view interactions] High throughput yes yes
SRBS2_HUMAN [view entry] [view interactions] High throughput yes no
SQSTM_HUMAN [view interactions] High throughput no yes
ZO1_HUMAN [view entry] [view interactions] High throughput yes no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
SMAD3_HUMAN [view interactions] High throughput no yes
RBTN2_HUMAN [view interactions] High throughput no yes
SMRD1_HUMAN [view interactions] High throughput no yes
RPAC1_HUMAN [view interactions] High throughput no no
STAT3_HUMAN [view entry] [view interactions] High throughput yes yes
GIT2_HUMAN [view interactions] High throughput no yes
TAB1_HUMAN [view interactions] High throughput no yes
POTE1_HUMAN [view interactions] High throughput no no
YTDC1_HUMAN [view interactions] High throughput no yes
NAL12_HUMAN [view interactions] High throughput no yes
IFT57_HUMAN [view interactions] High throughput no yes
POC1A_HUMAN [view interactions] High throughput no yes
S2541_HUMAN [view interactions] High throughput no no
RM12_HUMAN [view interactions] High throughput no yes
NELL2_HUMAN [view interactions] High throughput no no
TM205_HUMAN [view interactions] High throughput no yes
DNJC1_HUMAN [view interactions] High throughput no yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
SYVC_HUMAN [view interactions] High throughput no yes
POC1B_HUMAN [view interactions] High throughput no no
COR1B_HUMAN [view entry] [view interactions] High throughput yes no
IFT80_HUMAN [view interactions] High throughput no yes
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
RBGP1_HUMAN [view interactions] High throughput no yes
TMCC2_HUMAN [view interactions] High throughput no yes
FOXA3_HUMAN [view interactions] High throughput no yes
THMS1_HUMAN [view interactions] High throughput no no
UB2G2_HUMAN [view interactions] High throughput no yes
DKK1_HUMAN [view interactions] High throughput no no
FHL3_HUMAN [view interactions] High throughput no no
MGN_HUMAN [view interactions] High throughput no yes
SPT20_HUMAN [view interactions] High throughput no yes
FSD2_HUMAN [view interactions] High throughput no no
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
MAGAB_HUMAN [view interactions] High throughput no no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
DDX24_HUMAN [view interactions] High throughput no yes
IFT20_HUMAN [view interactions] High throughput no yes
FOXP3_HUMAN [view interactions] High throughput no no
FMNL1_HUMAN [view entry] [view interactions] High throughput yes no
CORO6_HUMAN [view interactions] High throughput no no
BICD2_HUMAN [view interactions] High throughput no yes
IF172_HUMAN [view interactions] High throughput no no
RBG1L_HUMAN [view interactions] High throughput no yes
TRAF7_HUMAN [view interactions] High throughput no yes
TJAP1_HUMAN [view entry] [view interactions] High throughput yes yes
TASOR_HUMAN [view interactions] High throughput no yes
CEP44_HUMAN [view interactions] High throughput no yes
COR2A_HUMAN [view entry] [view interactions] High throughput yes no
U2AF2_HUMAN [view interactions] High throughput no yes
RASF8_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
TADBP_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
KDM6B_HUMAN [view interactions] High throughput no yes
NEK2_HUMAN [view interactions] High throughput no no
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
TIA1_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
BRD4_HUMAN [view interactions] High throughput no yes
RIGI_HUMAN [view interactions] High throughput no yes
TRIM9_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
INSY1_HUMAN [view entry] [view interactions] High throughput yes yes
MATN2_HUMAN [view interactions] High throughput no no
L37A2_HUMAN [view interactions] High throughput no no
MUC15_HUMAN [view interactions] High throughput no yes
NPTXR_HUMAN [view entry] [view interactions] High throughput yes yes
CNGA4_HUMAN [view interactions] High throughput no no
CA162_HUMAN [view interactions] High throughput no yes
GBG8_HUMAN [view interactions] High throughput no no
SKA2_HUMAN [view interactions] High throughput no no
KTU_HUMAN [view interactions] High throughput no yes
K2C7_HUMAN [view interactions] High throughput no no
TMCC3_HUMAN [view interactions] High throughput no yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
CCD78_HUMAN [view interactions] High throughput no no
ZF69B_HUMAN [view interactions] High throughput no yes
COLQ_HUMAN [view interactions] High throughput no no
PSMD9_HUMAN [view interactions] High throughput no yes
CRBG2_HUMAN [view interactions] High throughput no no
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
EF1B_HUMAN [view entry] [view interactions] High throughput yes yes
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
KLK10_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
IKZF3_HUMAN [view interactions] High throughput no no
IKZF1_HUMAN [view interactions] High throughput no no
VIGLN_HUMAN [view entry] [view interactions] High throughput yes yes
MILK2_HUMAN [view interactions] High throughput no no
UBP11_HUMAN [view interactions] High throughput no yes
UBP36_HUMAN [view interactions] High throughput no yes
ITA2B_HUMAN [view interactions] High throughput no no
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
ASPDH_HUMAN [view interactions] High throughput no yes
NH2L1_HUMAN [view interactions] High throughput no yes
C1QB_HUMAN [view entry] [view interactions] High throughput yes no
DHX9_HUMAN [view interactions] High throughput no yes
PI42A_HUMAN [view entry] [view interactions] High throughput yes yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
AGR2_HUMAN [view interactions] High throughput no no
JCAD_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
BT3L4_HUMAN [view interactions] High throughput no yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
DREB_HUMAN [view entry] [view interactions] High throughput yes yes
DBNL_HUMAN [view entry] [view interactions] High throughput yes yes
WAC2C_HUMAN [view interactions] High throughput no yes
WAC2A_HUMAN [view interactions] High throughput no yes
FKB15_HUMAN [view entry] [view interactions] High throughput yes yes
LMTK2_HUMAN [view entry] [view interactions] High throughput yes yes
MYL6_HUMAN [view entry] [view interactions] High throughput yes no