Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NPTXR_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in NPTXR_HUMAN
GO:0043169 cation binding 71.4286 4 yes
GO:0046872 metal ion binding 71.4286 5 yes
GO:0000166 nucleotide binding 28.5714 4 no
GO:0005524 ATP binding 28.5714 5 no
GO:0017076 purine nucleotide binding 28.5714 5 no
GO:0030554 adenyl nucleotide binding 28.5714 6 no
GO:0032555 purine ribonucleotide binding 28.5714 4 no
GO:0032559 adenyl ribonucleotide binding 28.5714 5 no
GO:0035639 purine ribonucleoside triphosphate binding 28.5714 4 no
GO:0043168 anion binding 28.5714 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in NPTXR_HUMAN
GO:0071310 cellular response to organic substance 57.1429 4 no
GO:0022607 cellular component assembly 42.8571 4 no
GO:0048523 negative regulation of cellular process 42.8571 4 no
GO:0007268 chemical synaptic transmission 28.5714 7 no
GO:0098916 anterograde trans-synaptic signaling 28.5714 6 no
GO:0099536 synaptic signaling 28.5714 4 no
GO:0099537 trans-synaptic signaling 28.5714 5 no
GO:0006996 organelle organization 28.5714 4 no
GO:0008104 protein localization 28.5714 4 no
GO:0030030 cell projection organization 28.5714 4 no
GO:0070925 organelle assembly 28.5714 5 no
GO:1901701 cellular response to oxygen-containing compound 28.5714 4 no
GO:0010646 regulation of cell communication 28.5714 4 no
GO:0030334 regulation of cell migration 28.5714 5 no
GO:0030335 positive regulation of cell migration 28.5714 6 no
GO:0031396 regulation of protein ubiquitination 28.5714 9 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0034097 response to cytokine 28.5714 4 no
GO:0040017 positive regulation of locomotion 28.5714 4 no
GO:0042981 regulation of apoptotic process 28.5714 5 no
GO:0043066 negative regulation of apoptotic process 28.5714 6 no
GO:0043067 regulation of programmed cell death 28.5714 4 no
GO:0043069 negative regulation of programmed cell death 28.5714 5 no
GO:0043254 regulation of protein-containing complex assembly 28.5714 5 no
GO:0044087 regulation of cellular component biogenesis 28.5714 4 no
GO:0048522 positive regulation of cellular process 28.5714 4 no
GO:0051128 regulation of cellular component organization 28.5714 4 no
GO:0051129 negative regulation of cellular component organization 28.5714 5 no
GO:0051246 regulation of protein metabolic process 28.5714 5 no
GO:0060255 regulation of macromolecule metabolic process 28.5714 4 no
GO:0070670 response to interleukin-4 28.5714 5 no
GO:0071345 cellular response to cytokine stimulus 28.5714 5 no
GO:0071353 cellular response to interleukin-4 28.5714 6 no
GO:0080090 regulation of primary metabolic process 28.5714 4 no
GO:1901873 regulation of post-translational protein modification 28.5714 7 no
GO:1903320 regulation of protein modification by small protein conjugation or removal 28.5714 8 no
GO:2000145 regulation of cell motility 28.5714 4 no
GO:2000147 positive regulation of cell motility 28.5714 5 no
GO:0001894 tissue homeostasis 28.5714 4 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NPTX1_HUMAN [view entry] [view interactions] Low throughput yes yes
HDAC4_HUMAN [view interactions] High throughput no yes
ASF1A_HUMAN [view interactions] High throughput no no
PHC1_HUMAN [view interactions] High throughput no yes
NEUFC_HUMAN [view interactions] High throughput no yes
PSPC_HUMAN [view interactions] High throughput no no
FBX2_HUMAN [view entry] [view interactions] High throughput yes yes
COR1A_HUMAN [view entry] [view interactions] High throughput yes no
FBX11_HUMAN [view interactions] High throughput no no
SELN_HUMAN [view interactions] High throughput no yes
SIAE_HUMAN [view interactions] High throughput no yes
NPTX2_HUMAN [view entry] [view interactions] High throughput yes yes
PAR3L_HUMAN [view interactions] High throughput no yes
FINC_HUMAN [view interactions] High throughput no yes
HOOK2_HUMAN [view interactions] High throughput no yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes
AQP6_HUMAN [view interactions] High throughput no no
PTX4_HUMAN [view interactions] High throughput no no
CST9L_HUMAN [view interactions] High throughput no no
EMID1_HUMAN [view interactions] High throughput no yes
MFAP4_HUMAN [view interactions] High throughput no no
FHI2A_HUMAN [view interactions] High throughput no yes
ACACB_HUMAN [view interactions] High throughput no no
IL5RA_HUMAN [view interactions] High throughput no no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
ERP44_HUMAN [view interactions] High throughput no yes