FBX2_HUMAN
Evidence for PS localization
Functions
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type . [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FBX2_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 31.8841 | 4 | no |
| GO:0046872 | metal ion binding | 31.8841 | 5 | no |
| GO:0004842 | ubiquitin-protein transferase activity | 5.7971 | 4 | yes |
| GO:0016755 | aminoacyltransferase activity | 5.7971 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FBX2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 57.9710 | 4 | no |
| GO:0010646 | regulation of cell communication | 55.0725 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.7246 | 4 | no |
| GO:0009966 | regulation of signal transduction | 49.2754 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 49.2754 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 49.2754 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 44.9275 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 44.9275 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 39.1304 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 37.6812 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 37.6812 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 36.2319 | 4 | no |
| GO:0010468 | regulation of gene expression | 36.2319 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 36.2319 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 36.2319 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 34.7826 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.7826 | 5 | no |
| GO:0030030 | cell projection organization | 33.3333 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 33.3333 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 31.8841 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.8841 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.4348 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.4348 | 4 | no |
| GO:0008104 | protein localization | 30.4348 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 30.4348 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 30.4348 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 30.4348 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.9855 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 28.9855 | 5 | no |
| GO:2000145 | regulation of cell motility | 27.5362 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 27.5362 | 5 | no |
| GO:0022607 | cellular component assembly | 27.5362 | 4 | no |
| GO:0031399 | regulation of protein modification process | 27.5362 | 6 | yes |
| GO:0009968 | negative regulation of signal transduction | 26.0870 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 26.0870 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.0870 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 26.0870 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.0870 | 5 | no |
| GO:0036211 | protein modification process | 26.0870 | 4 | yes |
| GO:0043412 | macromolecule modification | 26.0870 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 26.0870 | 4 | no |
| GO:0030334 | regulation of cell migration | 26.0870 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 24.6377 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 24.6377 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.6377 | 4 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 24.6377 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 24.6377 | 5 | no |
| GO:0051049 | regulation of transport | 24.6377 | 4 | no |
| GO:0060284 | regulation of cell development | 24.6377 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.1884 | 5 | no |
| GO:0006996 | organelle organization | 23.1884 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.1884 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 23.1884 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 23.1884 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 23.1884 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 23.1884 | 5 | no |
| GO:0030162 | regulation of proteolysis | 21.7391 | 6 | no |
| GO:0031175 | neuron projection development | 21.7391 | 6 | no |
| GO:0050807 | regulation of synapse organization | 21.7391 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 21.7391 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 21.7391 | 4 | yes |
| GO:0051960 | regulation of nervous system development | 21.7391 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.7391 | 6 | no |
| GO:0032101 | regulation of response to external stimulus | 20.2899 | 4 | no |
| GO:0080134 | regulation of response to stress | 20.2899 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 20.2899 | 7 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.2899 | 5 | no |
| GO:0010629 | negative regulation of gene expression | 20.2899 | 7 | no |
| GO:0006508 | proteolysis | 20.2899 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 20.2899 | 4 | yes |
| GO:0030155 | regulation of cell adhesion | 20.2899 | 4 | no |
| GO:0050767 | regulation of neurogenesis | 20.2899 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 18.8406 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 15.9420 | 4 | yes |
| GO:0042176 | regulation of protein catabolic process | 14.4928 | 5 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 14.4928 | 4 | yes |
| GO:0030163 | protein catabolic process | 13.0435 | 4 | yes |
| GO:0019941 | modification-dependent protein catabolic process | 10.1449 | 6 | yes |
| GO:0032446 | protein modification by small protein conjugation | 10.1449 | 7 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 10.1449 | 5 | yes |
| GO:0043687 | post-translational protein modification | 10.1449 | 5 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 10.1449 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 10.1449 | 6 | yes |
| GO:1901873 | regulation of post-translational protein modification | 10.1449 | 7 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 10.1449 | 8 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 8.6957 | 7 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 8.6957 | 5 | yes |
| GO:0016567 | protein ubiquitination | 8.6957 | 8 | yes |
| GO:0031396 | regulation of protein ubiquitination | 8.6957 | 9 | yes |
| GO:0010498 | proteasomal protein catabolic process | 7.2464 | 5 | yes |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 7.2464 | 6 | yes |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 4.3478 | 7 | yes |
| GO:1901136 | carbohydrate derivative catabolic process | 4.3478 | 4 | yes |
| GO:0006516 | glycoprotein catabolic process | 2.8986 | 5 | yes |
| GO:0009100 | glycoprotein metabolic process | 2.8986 | 4 | yes |
| GO:0099170 | postsynaptic modulation of chemical synaptic transmission | 2.8986 | 6 | yes |
| GO:0099576 | regulation of protein catabolic process at postsynapse, modulating synaptic transmission | 2.8986 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SKP1_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TERA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BACE1_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL1_HUMAN | [view interactions] | Low throughput | no | yes |
| CXB2_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL7_HUMAN | [view interactions] | Low throughput | no | yes |
| ANC2_HUMAN | [view interactions] | Low throughput | no | no |
| RBX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TOR1A_HUMAN | [view interactions] | Low throughput | no | yes |
| A1AT_HUMAN | [view interactions] | Low throughput | no | no |
| SHPS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IL6RA_HUMAN | [view interactions] | Low throughput | no | no |
| IL6RB_HUMAN | [view interactions] | Low throughput | no | no |
| FBN1_HUMAN | [view interactions] | Low throughput | no | no |
| LAMP2_HUMAN | [view interactions] | Low throughput | no | yes |
| PDE4D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PAQRB_HUMAN | [view interactions] | Low throughput | no | no |
| FETUA_HUMAN | [view interactions] | Low throughput | no | no |
| UB2D2_HUMAN | [view interactions] | Low throughput | no | yes |
| UB2D1_HUMAN | [view interactions] | Low throughput | no | yes |
| UB2D3_HUMAN | [view interactions] | Low throughput | no | yes |
| UB2E1_HUMAN | [view interactions] | Low throughput | no | yes |
| UB2L3_HUMAN | [view interactions] | Low throughput | no | yes |
| FBX2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VPS36_HUMAN | [view interactions] | High throughput | no | yes |
| ITAV_HUMAN | [view interactions] | High throughput | no | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| CNTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADAM9_HUMAN | [view interactions] | High throughput | no | no |
| TM2D3_HUMAN | [view interactions] | High throughput | no | yes |
| ROBO1_HUMAN | [view interactions] | High throughput | no | yes |
| NELL2_HUMAN | [view interactions] | High throughput | no | no |
| ITA8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| POMT1_HUMAN | [view interactions] | High throughput | no | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| ITA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CHLE_HUMAN | [view interactions] | High throughput | no | no |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| ITA1_HUMAN | [view interactions] | High throughput | no | yes |
| VASN_HUMAN | [view interactions] | High throughput | no | yes |
| ITA2_HUMAN | [view interactions] | High throughput | no | yes |
| IPSP_HUMAN | [view interactions] | High throughput | no | no |
| NOMO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBLN4_HUMAN | [view interactions] | High throughput | no | no |
| EMB_HUMAN | [view interactions] | High throughput | no | no |
| ADA33_HUMAN | [view interactions] | High throughput | no | yes |
| SLIT2_HUMAN | [view interactions] | High throughput | no | no |
| SIA7E_HUMAN | [view interactions] | High throughput | no | no |
| BMP1_HUMAN | [view interactions] | High throughput | no | yes |
| OPCM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B4GT3_HUMAN | [view interactions] | High throughput | no | yes |
| ERO1B_HUMAN | [view interactions] | High throughput | no | yes |
| FOLR3_HUMAN | [view interactions] | High throughput | no | no |
| AMGO3_HUMAN | [view interactions] | High throughput | no | no |
| ERAP2_HUMAN | [view interactions] | High throughput | no | yes |
| GDF9_HUMAN | [view interactions] | High throughput | no | no |
| ARSK_HUMAN | [view interactions] | High throughput | no | no |
| CAP7_HUMAN | [view interactions] | High throughput | no | no |
| PCP_HUMAN | [view interactions] | High throughput | no | yes |
| CHSTC_HUMAN | [view interactions] | High throughput | no | yes |
| PIEZ1_HUMAN | [view interactions] | High throughput | no | no |
| RNT2_HUMAN | [view interactions] | High throughput | no | yes |
| CD109_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| CAV2_HUMAN | [view interactions] | High throughput | no | no |
| PO210_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMED9_HUMAN | [view interactions] | High throughput | no | yes |
| EMIL3_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMED4_HUMAN | [view interactions] | High throughput | no | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| LYRM4_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUN1_HUMAN | [view interactions] | High throughput | no | yes |
| PFD6_HUMAN | [view interactions] | High throughput | no | yes |
| LIGO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| LRIG1_HUMAN | [view interactions] | High throughput | no | yes |
| BRAP_HUMAN | [view interactions] | High throughput | no | yes |
| SUSD1_HUMAN | [view interactions] | High throughput | no | no |
| PAX4_HUMAN | [view interactions] | High throughput | no | no |
| ENPP5_HUMAN | [view interactions] | High throughput | no | yes |
| VSTM1_HUMAN | [view interactions] | High throughput | no | no |
| PLXC1_HUMAN | [view interactions] | High throughput | no | no |
| AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPT2_HUMAN | [view interactions] | High throughput | no | no |
| PLTP_HUMAN | [view interactions] | High throughput | no | no |
| MGMT_HUMAN | [view interactions] | High throughput | no | no |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR2_HUMAN | [view interactions] | High throughput | no | yes |
| S12A7_HUMAN | [view interactions] | High throughput | no | yes |
| NID2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMA1_HUMAN | [view interactions] | High throughput | no | no |
| EPHB4_HUMAN | [view interactions] | High throughput | no | yes |
| LRP2_HUMAN | [view interactions] | High throughput | no | no |
| SLAF7_HUMAN | [view interactions] | High throughput | no | no |
| PCDH9_HUMAN | [view interactions] | High throughput | no | no |
| NECT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLXD1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
| ITB5_HUMAN | [view interactions] | High throughput | no | yes |
| BOC_HUMAN | [view interactions] | High throughput | no | yes |
| PPAL_HUMAN | [view interactions] | High throughput | no | no |
| IF_HUMAN | [view interactions] | High throughput | no | yes |
| CLPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASIC4_HUMAN | [view interactions] | High throughput | no | no |
| CLN5_HUMAN | [view interactions] | High throughput | no | yes |
| CD166_HUMAN | [view interactions] | High throughput | no | no |
| CATZ_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NOE2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MA2B2_HUMAN | [view interactions] | High throughput | no | no |
| CDHR4_HUMAN | [view interactions] | High throughput | no | no |
| CEMIP_HUMAN | [view interactions] | High throughput | no | no |
| FFAR1_HUMAN | [view interactions] | High throughput | no | no |
| SCRB1_HUMAN | [view interactions] | High throughput | no | no |
| HEXB_HUMAN | [view interactions] | High throughput | no | no |
| PXDN_HUMAN | [view interactions] | High throughput | no | no |
| LYAG_HUMAN | [view interactions] | High throughput | no | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| IL25_HUMAN | [view interactions] | High throughput | no | no |
| CREG1_HUMAN | [view interactions] | High throughput | no | no |
| WNT7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PMGT2_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| TTC17_HUMAN | [view interactions] | High throughput | no | yes |
| INSL3_HUMAN | [view interactions] | High throughput | no | no |
| ATRN_HUMAN | [view interactions] | High throughput | no | yes |
| THSD4_HUMAN | [view interactions] | High throughput | no | no |
| MA2B1_HUMAN | [view interactions] | High throughput | no | yes |
| C1RL_HUMAN | [view interactions] | High throughput | no | yes |
| MANBA_HUMAN | [view interactions] | High throughput | no | yes |
| PRELP_HUMAN | [view interactions] | High throughput | no | no |
| COCH_HUMAN | [view interactions] | High throughput | no | no |
| DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSC2_HUMAN | [view interactions] | High throughput | no | no |
| SPRNG_HUMAN | [view interactions] | High throughput | no | yes |
| ATF6A_HUMAN | [view interactions] | High throughput | no | yes |
| SEM4G_HUMAN | [view interactions] | High throughput | no | yes |
| OFUT1_HUMAN | [view interactions] | High throughput | no | yes |
| WN10B_HUMAN | [view interactions] | High throughput | no | yes |
| CC28A_HUMAN | [view interactions] | High throughput | no | no |
| ST14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SE1L3_HUMAN | [view interactions] | High throughput | no | yes |
| LTBP4_HUMAN | [view interactions] | High throughput | no | yes |
| INGR1_HUMAN | [view interactions] | High throughput | no | no |
| CILP2_HUMAN | [view interactions] | High throughput | no | no |
| TPA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MER34_HUMAN | [view interactions] | High throughput | no | no |
| BTD_HUMAN | [view interactions] | High throughput | no | no |
| C4BPB_HUMAN | [view interactions] | High throughput | no | no |
| PLOD3_HUMAN | [view interactions] | High throughput | no | yes |
| AGRG6_HUMAN | [view interactions] | High throughput | no | no |
| SEM6A_HUMAN | [view interactions] | High throughput | no | yes |
| OSMR_HUMAN | [view interactions] | High throughput | no | yes |
| ADA17_HUMAN | [view interactions] | High throughput | no | yes |
| IGSF2_HUMAN | [view interactions] | High throughput | no | yes |
| CSTL1_HUMAN | [view interactions] | High throughput | no | no |
| GXLT1_HUMAN | [view interactions] | High throughput | no | no |
| NPTXR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| GPAA1_HUMAN | [view interactions] | High throughput | no | yes |
| CTHR1_HUMAN | [view interactions] | High throughput | no | yes |
| VGFR1_HUMAN | [view interactions] | High throughput | no | no |
| BMP4_HUMAN | [view interactions] | High throughput | no | no |
| SPA9_HUMAN | [view interactions] | High throughput | no | no |
| EPDR1_HUMAN | [view interactions] | High throughput | no | yes |
| ARSB_HUMAN | [view interactions] | High throughput | no | yes |
| I12R1_HUMAN | [view interactions] | High throughput | no | no |
| H6ST1_HUMAN | [view interactions] | High throughput | no | no |
| OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
| LIFR_HUMAN | [view interactions] | High throughput | no | no |
| CADM4_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA5_HUMAN | [view interactions] | High throughput | no | no |
| TINAL_HUMAN | [view interactions] | High throughput | no | no |
| SUCO_HUMAN | [view interactions] | High throughput | no | yes |
| LAMB3_HUMAN | [view interactions] | High throughput | no | yes |
| SCAR3_HUMAN | [view interactions] | High throughput | no | yes |
| LRP10_HUMAN | [view interactions] | High throughput | no | no |
| PLXA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ICAM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEM3C_HUMAN | [view interactions] | High throughput | no | no |
| CD47_HUMAN | [view interactions] | High throughput | no | no |
| NCLN_HUMAN | [view interactions] | High throughput | no | yes |
| GPI8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRG_HUMAN | [view interactions] | High throughput | no | no |
| TMM25_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRJ_HUMAN | [view interactions] | High throughput | no | yes |
| KLK5_HUMAN | [view interactions] | High throughput | no | no |
| PTPRK_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| GOLM2_HUMAN | [view interactions] | High throughput | no | yes |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| L1CAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRFN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGRN1_HUMAN | [view interactions] | High throughput | no | yes |
| COCA1_HUMAN | [view interactions] | High throughput | no | yes |
| LRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| PVR_HUMAN | [view interactions] | High throughput | no | yes |
| PIGS_HUMAN | [view interactions] | High throughput | no | yes |
| COIA1_HUMAN | [view interactions] | High throughput | no | no |
| ITA6_HUMAN | [view interactions] | High throughput | no | yes |
| TIMP1_HUMAN | [view interactions] | High throughput | no | no |
| CRLF1_HUMAN | [view interactions] | High throughput | no | no |
| HXK2_HUMAN | [view interactions] | High throughput | no | yes |
| SIAE_HUMAN | [view interactions] | High throughput | no | yes |
| SEM6B_HUMAN | [view interactions] | High throughput | no | yes |
| GNPTA_HUMAN | [view interactions] | High throughput | no | yes |
| QSOX1_HUMAN | [view interactions] | High throughput | no | no |
| PCYOX_HUMAN | [view interactions] | High throughput | no | yes |
| NICA_HUMAN | [view interactions] | High throughput | no | yes |
| LRIG2_HUMAN | [view interactions] | High throughput | no | yes |
| ROCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| SE6L2_HUMAN | [view interactions] | High throughput | no | yes |
| TM231_HUMAN | [view interactions] | High throughput | no | yes |
| LAMC3_HUMAN | [view interactions] | High throughput | no | no |
| MPRI_HUMAN | [view interactions] | High throughput | no | yes |
| GNS_HUMAN | [view interactions] | High throughput | no | yes |
| CA2D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNED1_HUMAN | [view interactions] | High throughput | no | yes |
| LAMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATS7_HUMAN | [view interactions] | High throughput | no | no |
| LAMA4_HUMAN | [view interactions] | High throughput | no | no |
| DUOX1_HUMAN | [view interactions] | High throughput | no | no |
| LAMB2_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN3_HUMAN | [view interactions] | High throughput | no | no |
| LAMC1_HUMAN | [view interactions] | High throughput | no | yes |
| MEST_HUMAN | [view interactions] | High throughput | no | no |
| LGMN_HUMAN | [view interactions] | High throughput | no | yes |
| JAG1_HUMAN | [view interactions] | High throughput | no | no |
| CD276_HUMAN | [view interactions] | High throughput | no | yes |
| AGRF1_HUMAN | [view interactions] | High throughput | no | no |
| ANR46_HUMAN | [view interactions] | High throughput | no | yes |
| S4A7_HUMAN | [view interactions] | High throughput | no | no |
| T131L_HUMAN | [view interactions] | High throughput | no | yes |
| LICH_HUMAN | [view interactions] | High throughput | no | yes |
| PKD2_HUMAN | [view interactions] | High throughput | no | yes |
| MINP1_HUMAN | [view interactions] | High throughput | no | yes |
| PGLT1_HUMAN | [view interactions] | High throughput | no | no |
| SC11A_HUMAN | [view interactions] | High throughput | no | no |
| HPSE_HUMAN | [view interactions] | High throughput | no | no |
| GDN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPBG_HUMAN | [view interactions] | High throughput | no | yes |
| CHST8_HUMAN | [view interactions] | High throughput | no | no |
| CTU1_HUMAN | [view interactions] | High throughput | no | no |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FPRP_HUMAN | [view interactions] | High throughput | no | yes |
| SCAP_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| TUTLA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRIG3_HUMAN | [view interactions] | High throughput | no | yes |
| GRAH_HUMAN | [view interactions] | High throughput | no | no |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| POMT2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMC2_HUMAN | [view interactions] | High throughput | no | no |
| BGLR_HUMAN | [view interactions] | High throughput | no | yes |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIA8D_HUMAN | [view interactions] | High throughput | no | yes |
| NOTC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H6ST2_HUMAN | [view interactions] | High throughput | no | no |
| NOTC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SORL_HUMAN | [view interactions] | High throughput | no | yes |
| NOTC3_HUMAN | [view interactions] | High throughput | no | yes |
| ATF6B_HUMAN | [view interactions] | High throughput | no | yes |
| AGRG1_HUMAN | [view interactions] | High throughput | no | yes |
| ASIC5_HUMAN | [view interactions] | High throughput | no | yes |
| CD48_HUMAN | [view interactions] | High throughput | no | no |
| CEIP2_HUMAN | [view interactions] | High throughput | no | yes |
| AGRA3_HUMAN | [view interactions] | High throughput | no | yes |
| SPHM_HUMAN | [view interactions] | High throughput | no | yes |
| CD14_HUMAN | [view interactions] | High throughput | no | no |
| EMC7_HUMAN | [view interactions] | High throughput | no | yes |
| GAS6_HUMAN | [view interactions] | High throughput | no | no |
| TMTC3_HUMAN | [view interactions] | High throughput | no | yes |
| GALT5_HUMAN | [view interactions] | High throughput | no | no |
| ANAG_HUMAN | [view interactions] | High throughput | no | no |
| SPIT1_HUMAN | [view interactions] | High throughput | no | yes |
| AMOL2_HUMAN | [view interactions] | High throughput | no | no |
| NEDD8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCAP_HUMAN | [view interactions] | High throughput | no | yes |
| PCSK5_HUMAN | [view interactions] | High throughput | no | yes |
| AGRV1_HUMAN | [view interactions] | High throughput | no | no |
| PRAM2_HUMAN | [view interactions] | High throughput | no | no |
| SEM4D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PAG15_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLXB2_HUMAN | [view interactions] | High throughput | no | yes |
| TGO1_HUMAN | [view interactions] | High throughput | no | yes |
| TM131_HUMAN | [view interactions] | High throughput | no | yes |
| TXD15_HUMAN | [view interactions] | High throughput | no | yes |
| PLGT3_HUMAN | [view interactions] | High throughput | no | no |
| MYORG_HUMAN | [view interactions] | High throughput | no | yes |
| CA2D2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| TPSN_HUMAN | [view interactions] | High throughput | no | yes |
| SNX9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRFN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| TECT2_HUMAN | [view interactions] | High throughput | no | yes |
| TGFB1_HUMAN | [view interactions] | High throughput | no | no |
| LAMA3_HUMAN | [view interactions] | High throughput | no | no |
| COEA1_HUMAN | [view interactions] | High throughput | no | no |
| LMF2_HUMAN | [view interactions] | High throughput | no | yes |
| SIA7D_HUMAN | [view interactions] | High throughput | no | no |
| BT2A1_HUMAN | [view interactions] | High throughput | no | yes |
| CD320_HUMAN | [view interactions] | High throughput | no | yes |
| EMIL2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC3_HUMAN | [view interactions] | High throughput | no | yes |
| EMC8_HUMAN | [view interactions] | High throughput | no | no |
| LAMB1_HUMAN | [view interactions] | High throughput | no | yes |
| VKGC_HUMAN | [view interactions] | High throughput | no | yes |
| GSLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAAA_HUMAN | [view interactions] | High throughput | no | yes |
| LAG3_HUMAN | [view interactions] | High throughput | no | no |
| PGBM_HUMAN | [view interactions] | High throughput | no | no |
| CSPG4_HUMAN | [view interactions] | High throughput | no | yes |
| NPTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATF_HUMAN | [view interactions] | High throughput | no | yes |
| LEPR_HUMAN | [view interactions] | High throughput | no | no |
| GLYC_HUMAN | [view interactions] | High throughput | no | no |
| AMOL1_HUMAN | [view interactions] | High throughput | no | no |
| PIGU_HUMAN | [view interactions] | High throughput | no | no |
| CO8A_HUMAN | [view interactions] | High throughput | no | no |
| PLBL2_HUMAN | [view interactions] | High throughput | no | yes |
| COL12_HUMAN | [view interactions] | High throughput | no | no |
| SULF2_HUMAN | [view interactions] | High throughput | no | yes |
| UNC5B_HUMAN | [view interactions] | High throughput | no | yes |
| CATL2_HUMAN | [view interactions] | High throughput | no | yes |
| TM39A_HUMAN | [view interactions] | High throughput | no | yes |
| SELN_HUMAN | [view interactions] | High throughput | no | yes |
| CHSTA_HUMAN | [view interactions] | High throughput | no | yes |
| CELR3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| MEGF8_HUMAN | [view interactions] | High throughput | no | yes |
| TXD11_HUMAN | [view interactions] | High throughput | no | yes |
| ABCA2_HUMAN | [view interactions] | High throughput | no | yes |
| MRC2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMF1_HUMAN | [view interactions] | High throughput | no | yes |
| OSTM1_HUMAN | [view interactions] | High throughput | no | yes |
| PCYXL_HUMAN | [view interactions] | High throughput | no | yes |
| KAT7_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTC13_HUMAN | [view interactions] | High throughput | no | no |
| TGBR3_HUMAN | [view interactions] | High throughput | no | yes |
| K319L_HUMAN | [view interactions] | High throughput | no | yes |
| FBN2_HUMAN | [view interactions] | High throughput | no | no |
| NOMO3_HUMAN | [view interactions] | High throughput | no | yes |
| TEN3_HUMAN | [view interactions] | High throughput | no | yes |
| DIAC_HUMAN | [view interactions] | High throughput | no | yes |
| CTF1_HUMAN | [view interactions] | High throughput | no | no |
| ENPP1_HUMAN | [view interactions] | High throughput | no | yes |
| EDIL3_HUMAN | [view interactions] | High throughput | no | yes |
| JAG2_HUMAN | [view interactions] | High throughput | no | yes |
| ECE1_HUMAN | [view interactions] | High throughput | no | yes |
| ADA23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| MERTK_HUMAN | [view interactions] | High throughput | no | yes |
| CGT_HUMAN | [view interactions] | High throughput | no | no |
| G6PE_HUMAN | [view interactions] | High throughput | no | yes |
| SDK2_HUMAN | [view interactions] | High throughput | no | no |
| KPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| I17RA_HUMAN | [view interactions] | High throughput | no | yes |
| CDHR2_HUMAN | [view interactions] | High throughput | no | yes |
| B3GL2_HUMAN | [view interactions] | High throughput | no | yes |
| CO6A1_HUMAN | [view interactions] | High throughput | no | no |
| CO6A2_HUMAN | [view interactions] | High throughput | no | no |
| VPS25_HUMAN | [view interactions] | High throughput | no | yes |
| EDEM2_HUMAN | [view interactions] | High throughput | no | yes |
| IGSF3_HUMAN | [view interactions] | High throughput | no | yes |
| RN157_HUMAN | [view interactions] | High throughput | no | no |
| NFS1_HUMAN | [view interactions] | High throughput | no | yes |
| AGRIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
| SULF1_HUMAN | [view interactions] | High throughput | no | no |
| NID1_HUMAN | [view interactions] | High throughput | no | no |
| CBPD_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENPP4_HUMAN | [view interactions] | High throughput | no | yes |
| ASPG_HUMAN | [view interactions] | High throughput | no | yes |
| FRAS1_HUMAN | [view interactions] | High throughput | no | yes |
| PIGT_HUMAN | [view interactions] | High throughput | no | no |
| IDUA_HUMAN | [view interactions] | High throughput | no | yes |
| CNTP3_HUMAN | [view interactions] | High throughput | no | yes |
| CAHD1_HUMAN | [view interactions] | High throughput | no | no |
| GRN_HUMAN | [view interactions] | High throughput | no | no |