Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ITA5_HUMAN

GO
G2C
SynaptomeDB

(Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in ITA5_HUMAN
GO:0043168 anion binding 35.9375 4 no
GO:0000166 nucleotide binding 32.8125 4 no
GO:0017076 purine nucleotide binding 31.2500 5 no
GO:0032555 purine ribonucleotide binding 31.2500 4 no
GO:0035639 purine ribonucleoside triphosphate binding 31.2500 4 no
GO:0003779 actin binding 29.6875 4 no
GO:0016462 pyrophosphatase activity 25.0000 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 25.0000 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 25.0000 6 no
GO:0003924 GTPase activity 23.4375 7 no
GO:0043169 cation binding 21.8750 4 yes
GO:0046872 metal ion binding 21.8750 5 yes
GO:0005525 GTP binding 21.8750 5 no
GO:0019001 guanyl nucleotide binding 21.8750 6 no
GO:0032561 guanyl ribonucleotide binding 21.8750 5 no
GO:0019900 kinase binding 20.3125 4 no
GO:0019901 protein kinase binding 20.3125 5 no
GO:0001618 virus receptor activity 6.2500 4 yes
GO:0005509 calcium ion binding 4.6875 6 yes
GO:0005126 cytokine receptor binding 3.1250 4 yes
GO:0005161 platelet-derived growth factor receptor binding 3.1250 5 yes
GO:0005172 vascular endothelial growth factor receptor binding 3.1250 5 yes
GO:0043184 vascular endothelial growth factor receptor 2 binding 3.1250 6 yes
GO:0070851 growth factor receptor binding 3.1250 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ITA5_HUMAN
GO:0048522 positive regulation of cellular process 56.2500 4 yes
GO:0048523 negative regulation of cellular process 50.0000 4 yes
GO:0051128 regulation of cellular component organization 48.4375 4 no
GO:0006996 organelle organization 40.6250 4 no
GO:0031323 regulation of cellular metabolic process 39.0625 4 yes
GO:0060255 regulation of macromolecule metabolic process 39.0625 4 yes
GO:0022607 cellular component assembly 37.5000 4 yes
GO:0080090 regulation of primary metabolic process 37.5000 4 yes
GO:0010646 regulation of cell communication 34.3750 4 yes
GO:0009893 positive regulation of metabolic process 32.8125 4 yes
GO:0030334 regulation of cell migration 32.8125 5 yes
GO:2000145 regulation of cell motility 32.8125 4 yes
GO:0044087 regulation of cellular component biogenesis 32.8125 4 no
GO:0051049 regulation of transport 32.8125 4 no
GO:0009966 regulation of signal transduction 31.2500 4 yes
GO:0048584 positive regulation of response to stimulus 31.2500 4 yes
GO:0009889 regulation of biosynthetic process 31.2500 4 no
GO:0097435 supramolecular fiber organization 31.2500 4 no
GO:0008104 protein localization 31.2500 4 no
GO:0010604 positive regulation of macromolecule metabolic process 29.6875 5 yes
GO:0007015 actin filament organization 29.6875 5 no
GO:0031326 regulation of cellular biosynthetic process 29.6875 5 no
GO:0042127 regulation of cell population proliferation 29.6875 4 no
GO:0033043 regulation of organelle organization 29.6875 5 no
GO:0031325 positive regulation of cellular metabolic process 28.1250 5 yes
GO:0007010 cytoskeleton organization 28.1250 5 no
GO:0032970 regulation of actin filament-based process 28.1250 4 no
GO:0009967 positive regulation of signal transduction 26.5625 5 yes
GO:0010647 positive regulation of cell communication 26.5625 5 yes
GO:0023056 positive regulation of signaling 26.5625 4 yes
GO:0043067 regulation of programmed cell death 26.5625 4 yes
GO:0010468 regulation of gene expression 26.5625 6 no
GO:0010556 regulation of macromolecule biosynthetic process 26.5625 5 no
GO:0030030 cell projection organization 26.5625 4 no
GO:0032956 regulation of actin cytoskeleton organization 26.5625 5 no
GO:0051493 regulation of cytoskeleton organization 26.5625 6 no
GO:1902531 regulation of intracellular signal transduction 26.5625 5 no
GO:0030155 regulation of cell adhesion 25.0000 4 yes
GO:0042981 regulation of apoptotic process 25.0000 5 yes
GO:0051240 positive regulation of multicellular organismal process 25.0000 4 yes
GO:0051130 positive regulation of cellular component organization 25.0000 5 no
GO:0120036 plasma membrane bounded cell projection organization 25.0000 5 no
GO:0051246 regulation of protein metabolic process 23.4375 5 yes
GO:0071702 organic substance transport 23.4375 4 no
GO:0060341 regulation of cellular localization 23.4375 4 no
GO:0030335 positive regulation of cell migration 21.8750 6 yes
GO:0040017 positive regulation of locomotion 21.8750 4 yes
GO:2000147 positive regulation of cell motility 21.8750 5 yes
GO:0031344 regulation of cell projection organization 21.8750 5 no
GO:0071310 cellular response to organic substance 21.8750 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.8750 6 no
GO:0071705 nitrogen compound transport 21.8750 4 no
GO:0009892 negative regulation of metabolic process 21.8750 4 no
GO:1902533 positive regulation of intracellular signal transduction 21.8750 6 no
GO:0032880 regulation of protein localization 21.8750 5 no
GO:0010810 regulation of cell-substrate adhesion 20.3125 5 yes
GO:0022603 regulation of anatomical structure morphogenesis 20.3125 4 yes
GO:0051094 positive regulation of developmental process 20.3125 4 yes
GO:0009891 positive regulation of biosynthetic process 20.3125 5 no
GO:0044089 positive regulation of cellular component biogenesis 20.3125 5 no
GO:0141124 intracellular signaling cassette 20.3125 4 no
GO:0008284 positive regulation of cell population proliferation 20.3125 5 no
GO:0110053 regulation of actin filament organization 20.3125 6 no
GO:1902903 regulation of supramolecular fiber organization 20.3125 5 no
GO:0043066 negative regulation of apoptotic process 18.7500 6 yes
GO:0043069 negative regulation of programmed cell death 18.7500 5 yes
GO:2000026 regulation of multicellular organismal development 18.7500 4 yes
GO:0019220 regulation of phosphate metabolic process 17.1875 6 yes
GO:0031399 regulation of protein modification process 17.1875 6 yes
GO:0034330 cell junction organization 17.1875 4 yes
GO:0051174 regulation of phosphorus metabolic process 17.1875 5 yes
GO:0051247 positive regulation of protein metabolic process 17.1875 6 yes
GO:0010562 positive regulation of phosphorus metabolic process 15.6250 6 yes
GO:0045785 positive regulation of cell adhesion 15.6250 5 yes
GO:0045937 positive regulation of phosphate metabolic process 15.6250 7 yes
GO:0001932 regulation of protein phosphorylation 14.0625 7 yes
GO:0001934 positive regulation of protein phosphorylation 14.0625 8 yes
GO:0031401 positive regulation of protein modification process 14.0625 7 yes
GO:0042325 regulation of phosphorylation 14.0625 7 yes
GO:0042327 positive regulation of phosphorylation 14.0625 8 yes
GO:0007160 cell-matrix adhesion 12.5000 4 yes
GO:0010811 positive regulation of cell-substrate adhesion 12.5000 6 yes
GO:0034329 cell junction assembly 12.5000 5 yes
GO:0007229 integrin-mediated signaling pathway 9.3750 4 yes
GO:0045765 regulation of angiogenesis 9.3750 5 yes
GO:0045766 positive regulation of angiogenesis 9.3750 6 yes
GO:0090287 regulation of cellular response to growth factor stimulus 9.3750 4 yes
GO:1901342 regulation of vasculature development 9.3750 5 yes
GO:1904018 positive regulation of vasculature development 9.3750 5 yes
GO:0050890 cognition 7.8125 4 yes
GO:0044319 wound healing, spreading of cells 6.2500 4 yes
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 6.2500 4 yes
GO:0007044 cell-substrate junction assembly 4.6875 6 yes
GO:0007159 leukocyte cell-cell adhesion 4.6875 4 yes
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 4.6875 5 yes
GO:0034113 heterotypic cell-cell adhesion 4.6875 4 yes
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 4.6875 8 yes
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 4.6875 9 yes
GO:0150115 cell-substrate junction organization 4.6875 5 yes
GO:0023035 CD40 signaling pathway 3.1250 4 yes
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 3.1250 6 yes
GO:0033631 cell-cell adhesion mediated by integrin 3.1250 4 yes
GO:0035313 wound healing, spreading of epidermal cells 3.1250 5 yes
GO:0035987 endodermal cell differentiation 3.1250 4 yes
GO:2000209 regulation of anoikis 3.1250 6 yes
GO:2000811 negative regulation of anoikis 3.1250 7 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
L1CAM_HUMAN [view entry] [view interactions] Low throughput yes yes
LG3BP_HUMAN [view interactions] Low throughput no no
UBAP1_HUMAN [view interactions] Low throughput no yes
VINC_HUMAN [view entry] [view interactions] Low throughput yes no
VTNC_HUMAN [view interactions] Low throughput no no
TLN1_HUMAN [view entry] [view interactions] Low throughput yes no
SHRPN_HUMAN [view entry] [view interactions] Low throughput yes yes
EGLN_HUMAN [view interactions] Low throughput no no
TGFR1_HUMAN [view interactions] Low throughput no no
ACVL1_HUMAN [view interactions] Low throughput no yes
ITB1_HUMAN [view entry] [view interactions] Low throughput yes no
NRP1_HUMAN [view entry] [view interactions] Low throughput yes yes
FINC_HUMAN [view interactions] Low throughput no yes
CCN2_HUMAN [view interactions] Low throughput no yes
PLPP3_HUMAN [view interactions] Low throughput no no
FIBG_HUMAN [view entry] [view interactions] Low throughput yes no
ADA15_HUMAN [view interactions] Low throughput no yes
X3CL1_HUMAN [view interactions] Low throughput no yes
ITB3_HUMAN [view entry] [view interactions] Low throughput yes no
CXA1_HUMAN [view entry] [view interactions] Low throughput yes yes
1433T_HUMAN [view entry] [view interactions] Low throughput yes yes
CD9_HUMAN [view entry] [view interactions] Low throughput yes no
TSP4_HUMAN [view interactions] Low throughput no no
FABPH_HUMAN [view entry] [view interactions] Low throughput yes no
MSS4_HUMAN [view interactions] Low throughput no yes
AUP1_HUMAN [view interactions] Low throughput no yes
GIPC1_HUMAN [view entry] [view interactions] Low throughput yes yes
ILK_HUMAN [view interactions] Low throughput no no
FGFR2_HUMAN [view interactions] Low throughput no yes
CBL_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
ATX3_HUMAN [view interactions] Low throughput no yes
SE1L1_HUMAN [view interactions] Low throughput no yes
ITB5_HUMAN [view interactions] Low throughput no yes
ANGP2_HUMAN [view interactions] Low throughput no no
CIB1_HUMAN [view interactions] Low throughput no no
TIMP2_HUMAN [view interactions] Low throughput no no
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
VGFR2_HUMAN [view interactions] Low throughput no no
MMP9_HUMAN [view entry] [view interactions] Low throughput yes no
IBP2_HUMAN [view interactions] Low throughput no no
RTN4_HUMAN [view entry] [view interactions] Low throughput yes yes
EGFR_HUMAN [view interactions] Low throughput no no
LEG1_HUMAN [view interactions] High throughput no yes
RN123_HUMAN [view interactions] High throughput no yes
LEG3_HUMAN [view interactions] High throughput no yes
WDR25_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
LCN1_HUMAN [view interactions] High throughput no no
NCTR3_HUMAN [view interactions] High throughput no no
TENS2_HUMAN [view interactions] High throughput no no
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
LEG12_HUMAN [view interactions] High throughput no no
TGM2_HUMAN [view interactions] High throughput no no
PSPC_HUMAN [view interactions] High throughput no no
IL5RA_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
CD59_HUMAN [view entry] [view interactions] High throughput yes no
PCDH1_HUMAN [view entry] [view interactions] High throughput yes yes
DEF1_HUMAN [view interactions] High throughput no no
BTNL2_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOC_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND3_HUMAN [view interactions] High throughput no no
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOD_HUMAN [view interactions] High throughput no no
RND2_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
TOP3B_HUMAN [view interactions] High throughput no no
GGH_HUMAN [view interactions] High throughput no yes
METK2_HUMAN [view interactions] High throughput no no
VP26B_HUMAN [view entry] [view interactions] High throughput yes yes
CLK1_HUMAN [view interactions] High throughput no yes
FUBP1_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
AT1B3_HUMAN [view interactions] High throughput no yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
CAH9_HUMAN [view interactions] High throughput no no
OTULL_HUMAN [view interactions] High throughput no no
ST7_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
CAV1_HUMAN [view interactions] High throughput no no
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
T106B_HUMAN [view interactions] High throughput no yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
STING_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes
ARC1B_HUMAN [view interactions] High throughput no no
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
CYTSA_HUMAN [view interactions] High throughput no yes
AP2B1_HUMAN [view entry] [view interactions] High throughput yes yes
LIMC1_HUMAN [view entry] [view interactions] High throughput yes no
MYO5A_HUMAN [view entry] [view interactions] High throughput yes yes
MY18A_HUMAN [view entry] [view interactions] High throughput yes yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
ARP5L_HUMAN [view entry] [view interactions] High throughput yes yes
ARPC5_HUMAN [view entry] [view interactions] High throughput yes yes
TMOD3_HUMAN [view interactions] High throughput no yes
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
LUZP1_HUMAN [view interactions] High throughput no yes
TMOD1_HUMAN [view entry] [view interactions] High throughput yes yes
DAPK3_HUMAN [view interactions] High throughput no yes
MICA3_HUMAN [view interactions] High throughput no yes
TPRN_HUMAN [view interactions] High throughput no yes
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
LEG8_HUMAN [view entry] [view interactions] High throughput yes yes
BTNL3_HUMAN [view interactions] High throughput no no
ADA32_HUMAN [view interactions] High throughput no no
TAFA4_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
CD81_HUMAN [view interactions] High throughput no no
GRK6_HUMAN [view interactions] High throughput no yes
STABP_HUMAN [view interactions] High throughput no yes
GP182_HUMAN [view interactions] High throughput no no
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
CTDSL_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
FBX6_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
FLNA_HUMAN [view entry] [view interactions] High throughput yes no
MYO6_HUMAN [view entry] [view interactions] High throughput yes no
RBBP6_HUMAN [view interactions] High throughput no yes
TPM1_HUMAN [view entry] [view interactions] High throughput yes no
TPM2_HUMAN [view entry] [view interactions] High throughput yes yes
TPM3_HUMAN [view entry] [view interactions] High throughput yes yes
LRRF2_HUMAN [view interactions] High throughput no yes
CYTSB_HUMAN [view entry] [view interactions] High throughput yes yes
RNF4_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
ST14_HUMAN [view entry] [view interactions] High throughput yes yes
ORC4_HUMAN [view interactions] High throughput no yes
BRE1B_HUMAN [view interactions] High throughput no yes
PA2GE_HUMAN [view interactions] High throughput no no
CAD23_HUMAN [view interactions] High throughput no yes
LY86_HUMAN [view interactions] High throughput no no
BAP31_HUMAN [view interactions] High throughput no yes
TXD16_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
MTNB_HUMAN [view interactions] High throughput no yes
UBAC1_HUMAN [view interactions] High throughput no yes
T106A_HUMAN [view interactions] High throughput no no
TMPSD_HUMAN [view interactions] High throughput no no
FBX2_HUMAN [view entry] [view interactions] High throughput yes yes