ITA5_HUMAN
(Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in ITA5_HUMAN |
---|---|---|---|---|
GO:0043168 | anion binding | 35.9375 | 4 | no |
GO:0000166 | nucleotide binding | 32.8125 | 4 | no |
GO:0017076 | purine nucleotide binding | 31.2500 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 31.2500 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 31.2500 | 4 | no |
GO:0003779 | actin binding | 29.6875 | 4 | no |
GO:0016462 | pyrophosphatase activity | 25.0000 | 5 | no |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 25.0000 | 4 | no |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 25.0000 | 6 | no |
GO:0003924 | GTPase activity | 23.4375 | 7 | no |
GO:0043169 | cation binding | 21.8750 | 4 | yes |
GO:0046872 | metal ion binding | 21.8750 | 5 | yes |
GO:0005525 | GTP binding | 21.8750 | 5 | no |
GO:0019001 | guanyl nucleotide binding | 21.8750 | 6 | no |
GO:0032561 | guanyl ribonucleotide binding | 21.8750 | 5 | no |
GO:0019900 | kinase binding | 20.3125 | 4 | no |
GO:0019901 | protein kinase binding | 20.3125 | 5 | no |
GO:0001618 | virus receptor activity | 6.2500 | 4 | yes |
GO:0005509 | calcium ion binding | 4.6875 | 6 | yes |
GO:0005126 | cytokine receptor binding | 3.1250 | 4 | yes |
GO:0005161 | platelet-derived growth factor receptor binding | 3.1250 | 5 | yes |
GO:0005172 | vascular endothelial growth factor receptor binding | 3.1250 | 5 | yes |
GO:0043184 | vascular endothelial growth factor receptor 2 binding | 3.1250 | 6 | yes |
GO:0070851 | growth factor receptor binding | 3.1250 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in ITA5_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 56.2500 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 48.4375 | 4 | no |
GO:0006996 | organelle organization | 40.6250 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 39.0625 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 39.0625 | 4 | yes |
GO:0022607 | cellular component assembly | 37.5000 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 37.5000 | 4 | yes |
GO:0010646 | regulation of cell communication | 34.3750 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 32.8125 | 4 | yes |
GO:0030334 | regulation of cell migration | 32.8125 | 5 | yes |
GO:2000145 | regulation of cell motility | 32.8125 | 4 | yes |
GO:0044087 | regulation of cellular component biogenesis | 32.8125 | 4 | no |
GO:0051049 | regulation of transport | 32.8125 | 4 | no |
GO:0009966 | regulation of signal transduction | 31.2500 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 31.2500 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 31.2500 | 4 | no |
GO:0097435 | supramolecular fiber organization | 31.2500 | 4 | no |
GO:0008104 | protein localization | 31.2500 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 29.6875 | 5 | yes |
GO:0007015 | actin filament organization | 29.6875 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 29.6875 | 5 | no |
GO:0042127 | regulation of cell population proliferation | 29.6875 | 4 | no |
GO:0033043 | regulation of organelle organization | 29.6875 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 28.1250 | 5 | yes |
GO:0007010 | cytoskeleton organization | 28.1250 | 5 | no |
GO:0032970 | regulation of actin filament-based process | 28.1250 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 26.5625 | 5 | yes |
GO:0010647 | positive regulation of cell communication | 26.5625 | 5 | yes |
GO:0023056 | positive regulation of signaling | 26.5625 | 4 | yes |
GO:0043067 | regulation of programmed cell death | 26.5625 | 4 | yes |
GO:0010468 | regulation of gene expression | 26.5625 | 6 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 26.5625 | 5 | no |
GO:0030030 | cell projection organization | 26.5625 | 4 | no |
GO:0032956 | regulation of actin cytoskeleton organization | 26.5625 | 5 | no |
GO:0051493 | regulation of cytoskeleton organization | 26.5625 | 6 | no |
GO:1902531 | regulation of intracellular signal transduction | 26.5625 | 5 | no |
GO:0030155 | regulation of cell adhesion | 25.0000 | 4 | yes |
GO:0042981 | regulation of apoptotic process | 25.0000 | 5 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 25.0000 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 25.0000 | 5 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 25.0000 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 23.4375 | 5 | yes |
GO:0071702 | organic substance transport | 23.4375 | 4 | no |
GO:0060341 | regulation of cellular localization | 23.4375 | 4 | no |
GO:0030335 | positive regulation of cell migration | 21.8750 | 6 | yes |
GO:0040017 | positive regulation of locomotion | 21.8750 | 4 | yes |
GO:2000147 | positive regulation of cell motility | 21.8750 | 5 | yes |
GO:0031344 | regulation of cell projection organization | 21.8750 | 5 | no |
GO:0071310 | cellular response to organic substance | 21.8750 | 4 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.8750 | 6 | no |
GO:0071705 | nitrogen compound transport | 21.8750 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 21.8750 | 4 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 21.8750 | 6 | no |
GO:0032880 | regulation of protein localization | 21.8750 | 5 | no |
GO:0010810 | regulation of cell-substrate adhesion | 20.3125 | 5 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 20.3125 | 4 | yes |
GO:0051094 | positive regulation of developmental process | 20.3125 | 4 | yes |
GO:0009891 | positive regulation of biosynthetic process | 20.3125 | 5 | no |
GO:0044089 | positive regulation of cellular component biogenesis | 20.3125 | 5 | no |
GO:0141124 | intracellular signaling cassette | 20.3125 | 4 | no |
GO:0008284 | positive regulation of cell population proliferation | 20.3125 | 5 | no |
GO:0110053 | regulation of actin filament organization | 20.3125 | 6 | no |
GO:1902903 | regulation of supramolecular fiber organization | 20.3125 | 5 | no |
GO:0043066 | negative regulation of apoptotic process | 18.7500 | 6 | yes |
GO:0043069 | negative regulation of programmed cell death | 18.7500 | 5 | yes |
GO:2000026 | regulation of multicellular organismal development | 18.7500 | 4 | yes |
GO:0019220 | regulation of phosphate metabolic process | 17.1875 | 6 | yes |
GO:0031399 | regulation of protein modification process | 17.1875 | 6 | yes |
GO:0034330 | cell junction organization | 17.1875 | 4 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 17.1875 | 5 | yes |
GO:0051247 | positive regulation of protein metabolic process | 17.1875 | 6 | yes |
GO:0010562 | positive regulation of phosphorus metabolic process | 15.6250 | 6 | yes |
GO:0045785 | positive regulation of cell adhesion | 15.6250 | 5 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 15.6250 | 7 | yes |
GO:0001932 | regulation of protein phosphorylation | 14.0625 | 7 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 14.0625 | 8 | yes |
GO:0031401 | positive regulation of protein modification process | 14.0625 | 7 | yes |
GO:0042325 | regulation of phosphorylation | 14.0625 | 7 | yes |
GO:0042327 | positive regulation of phosphorylation | 14.0625 | 8 | yes |
GO:0007160 | cell-matrix adhesion | 12.5000 | 4 | yes |
GO:0010811 | positive regulation of cell-substrate adhesion | 12.5000 | 6 | yes |
GO:0034329 | cell junction assembly | 12.5000 | 5 | yes |
GO:0007229 | integrin-mediated signaling pathway | 9.3750 | 4 | yes |
GO:0045765 | regulation of angiogenesis | 9.3750 | 5 | yes |
GO:0045766 | positive regulation of angiogenesis | 9.3750 | 6 | yes |
GO:0090287 | regulation of cellular response to growth factor stimulus | 9.3750 | 4 | yes |
GO:1901342 | regulation of vasculature development | 9.3750 | 5 | yes |
GO:1904018 | positive regulation of vasculature development | 9.3750 | 5 | yes |
GO:0050890 | cognition | 7.8125 | 4 | yes |
GO:0044319 | wound healing, spreading of cells | 6.2500 | 4 | yes |
GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecules | 6.2500 | 4 | yes |
GO:0007044 | cell-substrate junction assembly | 4.6875 | 6 | yes |
GO:0007159 | leukocyte cell-cell adhesion | 4.6875 | 4 | yes |
GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway | 4.6875 | 5 | yes |
GO:0034113 | heterotypic cell-cell adhesion | 4.6875 | 4 | yes |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 4.6875 | 8 | yes |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 4.6875 | 9 | yes |
GO:0150115 | cell-substrate junction organization | 4.6875 | 5 | yes |
GO:0023035 | CD40 signaling pathway | 3.1250 | 4 | yes |
GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway | 3.1250 | 6 | yes |
GO:0033631 | cell-cell adhesion mediated by integrin | 3.1250 | 4 | yes |
GO:0035313 | wound healing, spreading of epidermal cells | 3.1250 | 5 | yes |
GO:0035987 | endodermal cell differentiation | 3.1250 | 4 | yes |
GO:2000209 | regulation of anoikis | 3.1250 | 6 | yes |
GO:2000811 | negative regulation of anoikis | 3.1250 | 7 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
L1CAM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LG3BP_HUMAN | [view interactions] | Low throughput | no | no |
UBAP1_HUMAN | [view interactions] | Low throughput | no | yes |
VINC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
VTNC_HUMAN | [view interactions] | Low throughput | no | no |
TLN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SHRPN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EGLN_HUMAN | [view interactions] | Low throughput | no | no |
TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
ACVL1_HUMAN | [view interactions] | Low throughput | no | yes |
ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FINC_HUMAN | [view interactions] | Low throughput | no | yes |
CCN2_HUMAN | [view interactions] | Low throughput | no | yes |
PLPP3_HUMAN | [view interactions] | Low throughput | no | no |
FIBG_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ADA15_HUMAN | [view interactions] | Low throughput | no | yes |
X3CL1_HUMAN | [view interactions] | Low throughput | no | yes |
ITB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
1433T_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CD9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TSP4_HUMAN | [view interactions] | Low throughput | no | no |
FABPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MSS4_HUMAN | [view interactions] | Low throughput | no | yes |
AUP1_HUMAN | [view interactions] | Low throughput | no | yes |
GIPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ILK_HUMAN | [view interactions] | Low throughput | no | no |
FGFR2_HUMAN | [view interactions] | Low throughput | no | yes |
CBL_HUMAN | [view interactions] | Low throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
SE1L1_HUMAN | [view interactions] | Low throughput | no | yes |
ITB5_HUMAN | [view interactions] | Low throughput | no | yes |
ANGP2_HUMAN | [view interactions] | Low throughput | no | no |
CIB1_HUMAN | [view interactions] | Low throughput | no | no |
TIMP2_HUMAN | [view interactions] | Low throughput | no | no |
VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
MMP9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IBP2_HUMAN | [view interactions] | Low throughput | no | no |
RTN4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
LEG1_HUMAN | [view interactions] | High throughput | no | yes |
RN123_HUMAN | [view interactions] | High throughput | no | yes |
LEG3_HUMAN | [view interactions] | High throughput | no | yes |
WDR25_HUMAN | [view interactions] | High throughput | no | yes |
LEG9_HUMAN | [view interactions] | High throughput | no | yes |
LCN1_HUMAN | [view interactions] | High throughput | no | no |
NCTR3_HUMAN | [view interactions] | High throughput | no | no |
TENS2_HUMAN | [view interactions] | High throughput | no | no |
GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LEG12_HUMAN | [view interactions] | High throughput | no | no |
TGM2_HUMAN | [view interactions] | High throughput | no | no |
PSPC_HUMAN | [view interactions] | High throughput | no | no |
IL5RA_HUMAN | [view interactions] | High throughput | no | no |
RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CD59_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PCDH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEF1_HUMAN | [view interactions] | High throughput | no | no |
BTNL2_HUMAN | [view interactions] | High throughput | no | no |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
RHOQ_HUMAN | [view interactions] | High throughput | no | no |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
RHOF_HUMAN | [view interactions] | High throughput | no | no |
RHOU_HUMAN | [view interactions] | High throughput | no | no |
RHOH_HUMAN | [view interactions] | High throughput | no | yes |
RND3_HUMAN | [view interactions] | High throughput | no | no |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOD_HUMAN | [view interactions] | High throughput | no | no |
RND2_HUMAN | [view interactions] | High throughput | no | no |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
TOP3B_HUMAN | [view interactions] | High throughput | no | no |
GGH_HUMAN | [view interactions] | High throughput | no | yes |
METK2_HUMAN | [view interactions] | High throughput | no | no |
VP26B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLK1_HUMAN | [view interactions] | High throughput | no | yes |
FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CAH9_HUMAN | [view interactions] | High throughput | no | no |
OTULL_HUMAN | [view interactions] | High throughput | no | no |
ST7_HUMAN | [view interactions] | High throughput | no | yes |
GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
T106B_HUMAN | [view interactions] | High throughput | no | yes |
RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STING_HUMAN | [view interactions] | High throughput | no | yes |
TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARC1B_HUMAN | [view interactions] | High throughput | no | no |
ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARP5L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARPC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LUZP1_HUMAN | [view interactions] | High throughput | no | yes |
TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DAPK3_HUMAN | [view interactions] | High throughput | no | yes |
MICA3_HUMAN | [view interactions] | High throughput | no | yes |
TPRN_HUMAN | [view interactions] | High throughput | no | yes |
PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BTNL3_HUMAN | [view interactions] | High throughput | no | no |
ADA32_HUMAN | [view interactions] | High throughput | no | no |
TAFA4_HUMAN | [view interactions] | High throughput | no | no |
VCAM1_HUMAN | [view interactions] | High throughput | no | no |
CD81_HUMAN | [view interactions] | High throughput | no | no |
GRK6_HUMAN | [view interactions] | High throughput | no | yes |
STABP_HUMAN | [view interactions] | High throughput | no | yes |
GP182_HUMAN | [view interactions] | High throughput | no | no |
LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTDSL_HUMAN | [view interactions] | High throughput | no | no |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
KCNK3_HUMAN | [view interactions] | High throughput | no | no |
FBX6_HUMAN | [view interactions] | High throughput | no | yes |
CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RBBP6_HUMAN | [view interactions] | High throughput | no | yes |
TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
CYTSB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RNF4_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
ST14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ORC4_HUMAN | [view interactions] | High throughput | no | yes |
BRE1B_HUMAN | [view interactions] | High throughput | no | yes |
PA2GE_HUMAN | [view interactions] | High throughput | no | no |
CAD23_HUMAN | [view interactions] | High throughput | no | yes |
LY86_HUMAN | [view interactions] | High throughput | no | no |
BAP31_HUMAN | [view interactions] | High throughput | no | yes |
TXD16_HUMAN | [view interactions] | High throughput | no | yes |
PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTNB_HUMAN | [view interactions] | High throughput | no | yes |
UBAC1_HUMAN | [view interactions] | High throughput | no | yes |
T106A_HUMAN | [view interactions] | High throughput | no | no |
TMPSD_HUMAN | [view interactions] | High throughput | no | no |
FBX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |