Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ITA5_HUMAN

GO
G2C
SynaptomeDB

(Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in ITA5_HUMAN
GO:0017076 purine nucleotide binding 32.8571 4 no
GO:0032555 purine ribonucleotide binding 32.8571 4 no
GO:0035639 purine ribonucleoside triphosphate binding 32.8571 4 no
GO:0003779 actin binding 31.4286 4 no
GO:0019900 kinase binding 24.2857 4 no
GO:0019901 protein kinase binding 24.2857 5 no
GO:0046872 metal ion binding 21.4286 4 yes
GO:0003924 GTPase activity 21.4286 7 no
GO:0016462 pyrophosphatase activity 21.4286 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 21.4286 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 21.4286 6 no
GO:0070851 growth factor receptor binding 4.2857 4 yes
GO:0005126 cytokine receptor binding 2.8571 4 yes
GO:0005161 platelet-derived growth factor receptor binding 2.8571 5 yes
GO:0005172 vascular endothelial growth factor receptor binding 2.8571 5 yes
GO:0043184 vascular endothelial growth factor receptor 2 binding 2.8571 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ITA5_HUMAN
GO:0048522 positive regulation of cellular process 61.4286 4 yes
GO:0048523 negative regulation of cellular process 54.2857 4 yes
GO:0022607 cellular component assembly 45.7143 4 yes
GO:0006996 organelle organization 44.2857 4 no
GO:0051128 regulation of cellular component organization 44.2857 4 no
GO:0060255 regulation of macromolecule metabolic process 42.8571 4 yes
GO:0080090 regulation of primary metabolic process 42.8571 4 yes
GO:0031323 regulation of cellular metabolic process 41.4286 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 40.0000 4 yes
GO:0010646 regulation of cell communication 38.5714 4 yes
GO:0009893 positive regulation of metabolic process 37.1429 4 yes
GO:0009966 regulation of signal transduction 37.1429 4 yes
GO:0051049 regulation of transport 35.7143 4 no
GO:0030030 cell projection organization 35.7143 4 no
GO:0010604 positive regulation of macromolecule metabolic process 34.2857 5 yes
GO:0030334 regulation of cell migration 34.2857 5 yes
GO:2000145 regulation of cell motility 34.2857 4 yes
GO:0007010 cytoskeleton organization 34.2857 5 no
GO:0022603 regulation of anatomical structure morphogenesis 32.8571 4 yes
GO:0048584 positive regulation of response to stimulus 32.8571 4 yes
GO:0120036 plasma membrane bounded cell projection organization 32.8571 5 no
GO:0031325 positive regulation of cellular metabolic process 31.4286 5 yes
GO:0033043 regulation of organelle organization 31.4286 5 no
GO:0044087 regulation of cellular component biogenesis 31.4286 4 no
GO:0009967 positive regulation of signal transduction 30.0000 5 yes
GO:0010647 positive regulation of cell communication 30.0000 5 yes
GO:0010941 regulation of cell death 30.0000 4 yes
GO:0023056 positive regulation of signaling 30.0000 4 yes
GO:0030155 regulation of cell adhesion 30.0000 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 30.0000 5 yes
GO:0007015 actin filament organization 30.0000 5 no
GO:0097435 supramolecular fiber organization 30.0000 4 no
GO:0008104 protein localization 30.0000 4 no
GO:0043067 regulation of programmed cell death 28.5714 5 yes
GO:0009889 regulation of biosynthetic process 28.5714 4 no
GO:0010468 regulation of gene expression 28.5714 5 no
GO:0031326 regulation of cellular biosynthetic process 28.5714 5 no
GO:0045595 regulation of cell differentiation 28.5714 4 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 no
GO:0042981 regulation of apoptotic process 27.1429 6 yes
GO:0042127 regulation of cell population proliferation 27.1429 4 no
GO:0032970 regulation of actin filament-based process 27.1429 4 no
GO:0051493 regulation of cytoskeleton organization 27.1429 6 no
GO:0051094 positive regulation of developmental process 25.7143 4 yes
GO:0022604 regulation of cell morphogenesis 25.7143 5 no
GO:0031344 regulation of cell projection organization 25.7143 5 no
GO:0032956 regulation of actin cytoskeleton organization 25.7143 5 no
GO:0051130 positive regulation of cellular component organization 25.7143 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.7143 6 no
GO:0010810 regulation of cell-substrate adhesion 24.2857 5 yes
GO:0051240 positive regulation of multicellular organismal process 24.2857 4 yes
GO:0051246 regulation of protein metabolic process 24.2857 5 yes
GO:1902533 positive regulation of intracellular signal transduction 24.2857 6 no
GO:0032880 regulation of protein localization 24.2857 5 no
GO:0060341 regulation of cellular localization 24.2857 4 no
GO:0030335 positive regulation of cell migration 22.8571 6 yes
GO:0040017 positive regulation of locomotion 22.8571 4 yes
GO:2000147 positive regulation of cell motility 22.8571 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 22.8571 5 no
GO:0016192 vesicle-mediated transport 22.8571 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.8571 5 no
GO:0071702 organic substance transport 22.8571 4 no
GO:0071310 cellular response to organic substance 22.8571 4 no
GO:0051050 positive regulation of transport 22.8571 4 no
GO:0034330 cell junction organization 21.4286 4 yes
GO:0060548 negative regulation of cell death 21.4286 5 yes
GO:0071705 nitrogen compound transport 21.4286 4 no
GO:0030031 cell projection assembly 21.4286 5 no
GO:0019220 regulation of phosphate metabolic process 20.0000 6 yes
GO:0043066 negative regulation of apoptotic process 20.0000 7 yes
GO:0043069 negative regulation of programmed cell death 20.0000 6 yes
GO:0051174 regulation of phosphorus metabolic process 20.0000 5 yes
GO:0007229 integrin-mediated signaling pathway 18.5714 4 yes
GO:0010562 positive regulation of phosphorus metabolic process 18.5714 6 yes
GO:0031399 regulation of protein modification process 18.5714 6 yes
GO:0042325 regulation of phosphorylation 18.5714 7 yes
GO:0045785 positive regulation of cell adhesion 18.5714 5 yes
GO:0045937 positive regulation of phosphate metabolic process 18.5714 7 yes
GO:0051247 positive regulation of protein metabolic process 18.5714 6 yes
GO:0031401 positive regulation of protein modification process 17.1429 7 yes
GO:0034329 cell junction assembly 17.1429 5 yes
GO:0042327 positive regulation of phosphorylation 17.1429 8 yes
GO:2000026 regulation of multicellular organismal development 17.1429 4 yes
GO:0001932 regulation of protein phosphorylation 15.7143 7 yes
GO:0001934 positive regulation of protein phosphorylation 15.7143 8 yes
GO:0010811 positive regulation of cell-substrate adhesion 14.2857 6 yes
GO:0007044 cell-substrate junction assembly 8.5714 6 yes
GO:0045765 regulation of angiogenesis 8.5714 5 yes
GO:0045766 positive regulation of angiogenesis 8.5714 6 yes
GO:0050890 cognition 8.5714 4 yes
GO:0150115 cell-substrate junction organization 8.5714 5 yes
GO:1901342 regulation of vasculature development 8.5714 5 yes
GO:1904018 positive regulation of vasculature development 8.5714 5 yes
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 7.1429 8 yes
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 7.1429 9 yes
GO:0090287 regulation of cellular response to growth factor stimulus 7.1429 4 yes
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 5.7143 4 yes
GO:2000209 regulation of anoikis 5.7143 7 yes
GO:2000811 negative regulation of anoikis 5.7143 8 yes
GO:0007159 leukocyte cell-cell adhesion 4.2857 4 yes
GO:0007613 memory 4.2857 4 yes
GO:0034113 heterotypic cell-cell adhesion 4.2857 4 yes
GO:0044319 wound healing, spreading of cells 4.2857 4 yes
GO:0023035 CD40 signaling pathway 2.8571 4 yes
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 2.8571 5 yes
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 2.8571 6 yes
GO:0033631 cell-cell adhesion mediated by integrin 2.8571 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in ITA5_HUMAN
DOID:114 heart disease 4.2857 3 no
DOID:0080000 muscular disease 2.8571 3 no
DOID:3191 nemaline myopathy 2.8571 7 no
DOID:422 congenital structural myopathy 2.8571 6 no
DOID:423 myopathy 2.8571 5 no
DOID:66 muscle tissue disease 2.8571 4 no
DOID:0050700 cardiomyopathy 2.8571 4 no
DOID:0060036 intrinsic cardiomyopathy 2.8571 5 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SHRPN_HUMAN [view entry] [view interactions] Low throughput yes yes
EGLN_HUMAN [view interactions] Low throughput no no
TGFR1_HUMAN [view interactions] Low throughput no no
ACVL1_HUMAN [view interactions] Low throughput no yes
ITB1_HUMAN [view entry] [view interactions] Low throughput yes no
NRP1_HUMAN [view entry] [view interactions] Low throughput yes yes
FINC_HUMAN [view interactions] Low throughput no yes
CCN2_HUMAN [view interactions] Low throughput no yes
PLPP3_HUMAN [view interactions] Low throughput no no
FIBG_HUMAN [view entry] [view interactions] Low throughput yes no
ADA15_HUMAN [view interactions] Low throughput no yes
X3CL1_HUMAN [view interactions] Low throughput no yes
MMP9_HUMAN [view interactions] Low throughput no no
ITB3_HUMAN [view entry] [view interactions] Low throughput yes no
CXA1_HUMAN [view entry] [view interactions] Low throughput yes yes
1433T_HUMAN [view entry] [view interactions] Low throughput yes yes
CD9_HUMAN [view entry] [view interactions] Low throughput yes no
FABPH_HUMAN [view entry] [view interactions] Low throughput yes no
MSS4_HUMAN [view interactions] Low throughput no yes
AUP1_HUMAN [view interactions] Low throughput no yes
GIPC1_HUMAN [view entry] [view interactions] Low throughput yes yes
ILK_HUMAN [view interactions] Low throughput no no
FGFR2_HUMAN [view interactions] Low throughput no yes
CBL_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
ATX3_HUMAN [view interactions] Low throughput no yes
SE1L1_HUMAN [view interactions] Low throughput no yes
ITB5_HUMAN [view interactions] Low throughput no yes
ANGP2_HUMAN [view interactions] Low throughput no no
CIB1_HUMAN [view interactions] Low throughput no no
TIMP2_HUMAN [view interactions] Low throughput no no
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
VGFR2_HUMAN [view interactions] Low throughput no no
IBP2_HUMAN [view interactions] Low throughput no no
RTN4_HUMAN [view entry] [view interactions] Low throughput yes yes
EGFR_HUMAN [view interactions] Low throughput no no
L1CAM_HUMAN [view entry] [view interactions] Low throughput yes yes
LG3BP_HUMAN [view interactions] Low throughput no no
UBAP1_HUMAN [view interactions] Low throughput no yes
VINC_HUMAN [view entry] [view interactions] Low throughput yes no
TLN1_HUMAN [view entry] [view interactions] Low throughput yes no
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
TPRN_HUMAN [view interactions] High throughput no yes
MICA3_HUMAN [view interactions] High throughput no yes
DAPK3_HUMAN [view interactions] High throughput no yes
TMOD1_HUMAN [view entry] [view interactions] High throughput yes yes
LUZP1_HUMAN [view interactions] High throughput no yes
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
TMOD3_HUMAN [view interactions] High throughput no yes
ARPC5_HUMAN [view interactions] High throughput no yes
ARP5L_HUMAN [view entry] [view interactions] High throughput yes yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
MY18A_HUMAN [view entry] [view interactions] High throughput yes yes
MYO5A_HUMAN [view entry] [view interactions] High throughput yes yes
LIMC1_HUMAN [view entry] [view interactions] High throughput yes no
AP2B1_HUMAN [view entry] [view interactions] High throughput yes yes
CYTSA_HUMAN [view interactions] High throughput no yes
ARP3_HUMAN [view entry] [view interactions] High throughput yes yes
ARC1B_HUMAN [view interactions] High throughput no no
LEG8_HUMAN [view entry] [view interactions] High throughput yes yes
BTNL3_HUMAN [view interactions] High throughput no no
ADA32_HUMAN [view interactions] High throughput no no
TAFA4_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
CD81_HUMAN [view interactions] High throughput no no
GRK6_HUMAN [view interactions] High throughput no yes
STABP_HUMAN [view interactions] High throughput no yes
GP182_HUMAN [view interactions] High throughput no no
LAMP1_HUMAN [view interactions] High throughput no yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
CTDSL_HUMAN [view interactions] High throughput no no
FBX6_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
FLNA_HUMAN [view entry] [view interactions] High throughput yes no
MYO6_HUMAN [view entry] [view interactions] High throughput yes no
RBBP6_HUMAN [view interactions] High throughput no yes
TPM1_HUMAN [view entry] [view interactions] High throughput yes no
TPM2_HUMAN [view entry] [view interactions] High throughput yes yes
TPM3_HUMAN [view entry] [view interactions] High throughput yes yes
LRRF2_HUMAN [view interactions] High throughput no yes
CYTSB_HUMAN [view entry] [view interactions] High throughput yes yes
RNF4_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
ST14_HUMAN [view entry] [view interactions] High throughput yes yes
ORC4_HUMAN [view interactions] High throughput no yes
BRE1B_HUMAN [view interactions] High throughput no yes
PA2GE_HUMAN [view interactions] High throughput no no
CAD23_HUMAN [view interactions] High throughput no yes
LY86_HUMAN [view interactions] High throughput no no
BAP31_HUMAN [view interactions] High throughput no yes
TXD16_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
MTNB_HUMAN [view interactions] High throughput no yes
UBAC1_HUMAN [view interactions] High throughput no yes
T106A_HUMAN [view interactions] High throughput no no
TMPSD_HUMAN [view interactions] High throughput no no
FBX2_HUMAN [view entry] [view interactions] High throughput yes yes
LEG1_HUMAN [view interactions] High throughput no yes
RN123_HUMAN [view interactions] High throughput no yes
LEG3_HUMAN [view interactions] High throughput no yes
WDR25_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
LCN1_HUMAN [view interactions] High throughput no no
NCTR3_HUMAN [view interactions] High throughput no no
TNS2_HUMAN [view interactions] High throughput no no
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
LEG12_HUMAN [view interactions] High throughput no no
TGM2_HUMAN [view interactions] High throughput no no
PSPC_HUMAN [view interactions] High throughput no no
IL5RA_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
CD59_HUMAN [view entry] [view interactions] High throughput yes no
PCDH1_HUMAN [view entry] [view interactions] High throughput yes yes
DEF1_HUMAN [view interactions] High throughput no no
BTNL2_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOC_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND3_HUMAN [view interactions] High throughput no no
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOD_HUMAN [view interactions] High throughput no no
RND2_HUMAN [view interactions] High throughput no no
GGH_HUMAN [view interactions] High throughput no yes
METK2_HUMAN [view interactions] High throughput no no
VP26B_HUMAN [view interactions] High throughput no yes
CLK1_HUMAN [view interactions] High throughput no yes
FUBP1_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
AT1B3_HUMAN [view interactions] High throughput no yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
CAH9_HUMAN [view interactions] High throughput no no
OTULL_HUMAN [view interactions] High throughput no no
ST7_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
CAV1_HUMAN [view interactions] High throughput no no
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
T106B_HUMAN [view interactions] High throughput no yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
COIA1_HUMAN [view interactions] Computational no no
ITAL_HUMAN [view interactions] Computational no no
ITA10_HUMAN [view interactions] Computational no no
OSTP_HUMAN [view interactions] Computational no yes
ITAV_HUMAN [view interactions] Computational no yes
FAK1_HUMAN [view entry] [view interactions] Computational yes yes
CEAM8_HUMAN [view interactions] Computational no no
TIE2_HUMAN [view interactions] Computational no no
UPAR_HUMAN [view interactions] Computational no yes
UROK_HUMAN [view interactions] Computational no no
LAMA5_HUMAN [view entry] [view interactions] Computational yes no
ITB8_HUMAN [view interactions] Computational no no
ITA4_HUMAN [view interactions] Computational no no
TLN2_HUMAN [view entry] [view interactions] Computational yes yes
VEGFD_HUMAN [view interactions] Computational no no
CD28_HUMAN [view interactions] Computational no no
CO1A1_HUMAN [view interactions] Computational no yes
ITB4_HUMAN [view entry] [view interactions] Computational yes yes
VTNC_HUMAN [view interactions] Computational no no
ITA3_HUMAN [view entry] [view interactions] Computational yes yes
ACTN1_HUMAN [view entry] [view interactions] Computational yes yes
FAK2_HUMAN [view entry] [view interactions] Computational yes yes
PEBB_HUMAN [view interactions] Computational no no
FBN1_HUMAN [view interactions] Computational no no
CEAM6_HUMAN [view interactions] Computational no no
ITA11_HUMAN [view interactions] Computational no yes
ANGP1_HUMAN [view interactions] Computational no no
ITB7_HUMAN [view interactions] Computational no no
CEAM1_HUMAN [view interactions] Computational no no
JAM3_HUMAN [view interactions] Computational no no
NISCH_HUMAN [view interactions] Computational no yes
ITA1_HUMAN [view interactions] Computational no yes
ITA8_HUMAN [view entry] [view interactions] Computational yes no
ITAD_HUMAN [view interactions] Computational no no
CD80_HUMAN [view interactions] Computational no no
ACTN4_HUMAN [view entry] [view interactions] Computational yes yes
VGFR3_HUMAN [view interactions] Computational no yes
ITA2_HUMAN [view interactions] Computational no yes
ITB2_HUMAN [view interactions] Computational no no
LAMA2_HUMAN [view interactions] Computational no no
FIBB_HUMAN [view entry] [view interactions] Computational yes no
SKAP2_HUMAN [view interactions] Computational no no
LAMA1_HUMAN [view interactions] Computational no no
LAMC1_HUMAN [view interactions] Computational no yes
JAM2_HUMAN [view interactions] Computational no no
LAMA3_HUMAN [view interactions] Computational no no
SRC_HUMAN [view entry] [view interactions] Computational yes no
ITB6_HUMAN [view interactions] Computational no no
RUNX2_HUMAN [view interactions] Computational no no