ITA5_HUMAN
(Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ITA5_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 35.9375 | 4 | no |
| GO:0000166 | nucleotide binding | 32.8125 | 4 | no |
| GO:0017076 | purine nucleotide binding | 31.2500 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 31.2500 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 31.2500 | 4 | no |
| GO:0003779 | actin binding | 29.6875 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 25.0000 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 25.0000 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 25.0000 | 6 | no |
| GO:0003924 | GTPase activity | 23.4375 | 7 | no |
| GO:0043169 | cation binding | 21.8750 | 4 | yes |
| GO:0046872 | metal ion binding | 21.8750 | 5 | yes |
| GO:0005525 | GTP binding | 21.8750 | 5 | no |
| GO:0019001 | guanyl nucleotide binding | 21.8750 | 6 | no |
| GO:0032561 | guanyl ribonucleotide binding | 21.8750 | 5 | no |
| GO:0019900 | kinase binding | 20.3125 | 4 | no |
| GO:0019901 | protein kinase binding | 20.3125 | 5 | no |
| GO:0001618 | virus receptor activity | 6.2500 | 4 | yes |
| GO:0005509 | calcium ion binding | 4.6875 | 6 | yes |
| GO:0005126 | cytokine receptor binding | 3.1250 | 4 | yes |
| GO:0005161 | platelet-derived growth factor receptor binding | 3.1250 | 5 | yes |
| GO:0005172 | vascular endothelial growth factor receptor binding | 3.1250 | 5 | yes |
| GO:0043184 | vascular endothelial growth factor receptor 2 binding | 3.1250 | 6 | yes |
| GO:0070851 | growth factor receptor binding | 3.1250 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ITA5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 56.2500 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 48.4375 | 4 | no |
| GO:0006996 | organelle organization | 40.6250 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 39.0625 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 39.0625 | 4 | yes |
| GO:0022607 | cellular component assembly | 37.5000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 37.5000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 34.3750 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 32.8125 | 4 | yes |
| GO:0030334 | regulation of cell migration | 32.8125 | 5 | yes |
| GO:2000145 | regulation of cell motility | 32.8125 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 32.8125 | 4 | no |
| GO:0051049 | regulation of transport | 32.8125 | 4 | no |
| GO:0009966 | regulation of signal transduction | 31.2500 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 31.2500 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 31.2500 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 31.2500 | 4 | no |
| GO:0008104 | protein localization | 31.2500 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.6875 | 5 | yes |
| GO:0007015 | actin filament organization | 29.6875 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 29.6875 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 29.6875 | 4 | no |
| GO:0033043 | regulation of organelle organization | 29.6875 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.1250 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 28.1250 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 28.1250 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.5625 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 26.5625 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 26.5625 | 4 | yes |
| GO:0043067 | regulation of programmed cell death | 26.5625 | 4 | yes |
| GO:0010468 | regulation of gene expression | 26.5625 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 26.5625 | 5 | no |
| GO:0030030 | cell projection organization | 26.5625 | 4 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 26.5625 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 26.5625 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.5625 | 5 | no |
| GO:0030155 | regulation of cell adhesion | 25.0000 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 25.0000 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 25.0000 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 25.0000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 23.4375 | 5 | yes |
| GO:0071702 | organic substance transport | 23.4375 | 4 | no |
| GO:0060341 | regulation of cellular localization | 23.4375 | 4 | no |
| GO:0030335 | positive regulation of cell migration | 21.8750 | 6 | yes |
| GO:0040017 | positive regulation of locomotion | 21.8750 | 4 | yes |
| GO:2000147 | positive regulation of cell motility | 21.8750 | 5 | yes |
| GO:0031344 | regulation of cell projection organization | 21.8750 | 5 | no |
| GO:0071310 | cellular response to organic substance | 21.8750 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.8750 | 6 | no |
| GO:0071705 | nitrogen compound transport | 21.8750 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 21.8750 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 21.8750 | 6 | no |
| GO:0032880 | regulation of protein localization | 21.8750 | 5 | no |
| GO:0010810 | regulation of cell-substrate adhesion | 20.3125 | 5 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 20.3125 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 20.3125 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 20.3125 | 5 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 20.3125 | 5 | no |
| GO:0141124 | intracellular signaling cassette | 20.3125 | 4 | no |
| GO:0008284 | positive regulation of cell population proliferation | 20.3125 | 5 | no |
| GO:0110053 | regulation of actin filament organization | 20.3125 | 6 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 20.3125 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 18.7500 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 18.7500 | 5 | yes |
| GO:2000026 | regulation of multicellular organismal development | 18.7500 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 17.1875 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 17.1875 | 6 | yes |
| GO:0034330 | cell junction organization | 17.1875 | 4 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 17.1875 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 17.1875 | 6 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 15.6250 | 6 | yes |
| GO:0045785 | positive regulation of cell adhesion | 15.6250 | 5 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 15.6250 | 7 | yes |
| GO:0001932 | regulation of protein phosphorylation | 14.0625 | 7 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 14.0625 | 8 | yes |
| GO:0031401 | positive regulation of protein modification process | 14.0625 | 7 | yes |
| GO:0042325 | regulation of phosphorylation | 14.0625 | 7 | yes |
| GO:0042327 | positive regulation of phosphorylation | 14.0625 | 8 | yes |
| GO:0007160 | cell-matrix adhesion | 12.5000 | 4 | yes |
| GO:0010811 | positive regulation of cell-substrate adhesion | 12.5000 | 6 | yes |
| GO:0034329 | cell junction assembly | 12.5000 | 5 | yes |
| GO:0007229 | integrin-mediated signaling pathway | 9.3750 | 4 | yes |
| GO:0045765 | regulation of angiogenesis | 9.3750 | 5 | yes |
| GO:0045766 | positive regulation of angiogenesis | 9.3750 | 6 | yes |
| GO:0090287 | regulation of cellular response to growth factor stimulus | 9.3750 | 4 | yes |
| GO:1901342 | regulation of vasculature development | 9.3750 | 5 | yes |
| GO:1904018 | positive regulation of vasculature development | 9.3750 | 5 | yes |
| GO:0050890 | cognition | 7.8125 | 4 | yes |
| GO:0044319 | wound healing, spreading of cells | 6.2500 | 4 | yes |
| GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecules | 6.2500 | 4 | yes |
| GO:0007044 | cell-substrate junction assembly | 4.6875 | 6 | yes |
| GO:0007159 | leukocyte cell-cell adhesion | 4.6875 | 4 | yes |
| GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway | 4.6875 | 5 | yes |
| GO:0034113 | heterotypic cell-cell adhesion | 4.6875 | 4 | yes |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 4.6875 | 8 | yes |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 4.6875 | 9 | yes |
| GO:0150115 | cell-substrate junction organization | 4.6875 | 5 | yes |
| GO:0023035 | CD40 signaling pathway | 3.1250 | 4 | yes |
| GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway | 3.1250 | 6 | yes |
| GO:0033631 | cell-cell adhesion mediated by integrin | 3.1250 | 4 | yes |
| GO:0035313 | wound healing, spreading of epidermal cells | 3.1250 | 5 | yes |
| GO:0035987 | endodermal cell differentiation | 3.1250 | 4 | yes |
| GO:2000209 | regulation of anoikis | 3.1250 | 6 | yes |
| GO:2000811 | negative regulation of anoikis | 3.1250 | 7 | yes |
Disease
No data found.
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| L1CAM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LG3BP_HUMAN | [view interactions] | Low throughput | no | no |
| UBAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VTNC_HUMAN | [view interactions] | Low throughput | no | no |
| TLN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SHRPN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EGLN_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| ACVL1_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FINC_HUMAN | [view interactions] | Low throughput | no | yes |
| CCN2_HUMAN | [view interactions] | Low throughput | no | yes |
| PLPP3_HUMAN | [view interactions] | Low throughput | no | no |
| FIBG_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ADA15_HUMAN | [view interactions] | Low throughput | no | yes |
| X3CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TSP4_HUMAN | [view interactions] | Low throughput | no | no |
| FABPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MSS4_HUMAN | [view interactions] | Low throughput | no | yes |
| AUP1_HUMAN | [view interactions] | Low throughput | no | yes |
| GIPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ILK_HUMAN | [view interactions] | Low throughput | no | no |
| FGFR2_HUMAN | [view interactions] | Low throughput | no | yes |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
| SE1L1_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB5_HUMAN | [view interactions] | Low throughput | no | yes |
| ANGP2_HUMAN | [view interactions] | Low throughput | no | no |
| CIB1_HUMAN | [view interactions] | Low throughput | no | no |
| TIMP2_HUMAN | [view interactions] | Low throughput | no | no |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| MMP9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| IBP2_HUMAN | [view interactions] | Low throughput | no | no |
| RTN4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| LEG1_HUMAN | [view interactions] | High throughput | no | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| WDR25_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| LCN1_HUMAN | [view interactions] | High throughput | no | no |
| NCTR3_HUMAN | [view interactions] | High throughput | no | no |
| TENS2_HUMAN | [view interactions] | High throughput | no | no |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG12_HUMAN | [view interactions] | High throughput | no | no |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| PSPC_HUMAN | [view interactions] | High throughput | no | no |
| IL5RA_HUMAN | [view interactions] | High throughput | no | no |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD59_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCDH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEF1_HUMAN | [view interactions] | High throughput | no | no |
| BTNL2_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| GGH_HUMAN | [view interactions] | High throughput | no | yes |
| METK2_HUMAN | [view interactions] | High throughput | no | no |
| VP26B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLK1_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP1_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| OTULL_HUMAN | [view interactions] | High throughput | no | no |
| ST7_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARC1B_HUMAN | [view interactions] | High throughput | no | no |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP5L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LUZP1_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAPK3_HUMAN | [view interactions] | High throughput | no | yes |
| MICA3_HUMAN | [view interactions] | High throughput | no | yes |
| TPRN_HUMAN | [view interactions] | High throughput | no | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTNL3_HUMAN | [view interactions] | High throughput | no | no |
| ADA32_HUMAN | [view interactions] | High throughput | no | no |
| TAFA4_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| GRK6_HUMAN | [view interactions] | High throughput | no | yes |
| STABP_HUMAN | [view interactions] | High throughput | no | yes |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTDSL_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBBP6_HUMAN | [view interactions] | High throughput | no | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| CYTSB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ST14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ORC4_HUMAN | [view interactions] | High throughput | no | yes |
| BRE1B_HUMAN | [view interactions] | High throughput | no | yes |
| PA2GE_HUMAN | [view interactions] | High throughput | no | no |
| CAD23_HUMAN | [view interactions] | High throughput | no | yes |
| LY86_HUMAN | [view interactions] | High throughput | no | no |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| TXD16_HUMAN | [view interactions] | High throughput | no | yes |
| PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTNB_HUMAN | [view interactions] | High throughput | no | yes |
| UBAC1_HUMAN | [view interactions] | High throughput | no | yes |
| T106A_HUMAN | [view interactions] | High throughput | no | no |
| TMPSD_HUMAN | [view interactions] | High throughput | no | no |
| FBX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |