Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MYO6_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Myosins are actin-based motor molecules with ATPase activity . Unconventional myosins serve in intracellular movements . Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments (PubMed). Has slow rate of actin-activated ADP release due to weak ATP binding . Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration . Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway (PubMed). Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells (PubMed). May act as a regulator of F-actin dynamics . As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton (PubMed). May play a role in transporting DAB2 from the plasma membrane to specific cellular targets . May play a role in the extension and network organization of neurites . Required for structural integrity of inner ear hair cells . Modulates RNA polymerase II-dependent transcription (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
442 Cys Tyr Deafness,autosomaldominant,22(DFNA22) -
216 Glu Val Deafness,autosomalrecessive,37(DFNB37) -
246 His Arg Deafness,autosomaldominant22,withhypertrophiccardiomyopathy(DFNHCM) -

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in MYO6_HUMAN
GO:0019900 kinase binding 26.2821 4 no
GO:0019901 protein kinase binding 24.3590 5 no
GO:0003723 RNA binding 23.7179 4 no
GO:0017076 purine nucleotide binding 22.4359 4 yes
GO:0032555 purine ribonucleotide binding 22.4359 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 22.4359 4 yes
GO:0003779 actin binding 19.2308 4 yes
GO:0005524 ATP binding 17.9487 5 yes
GO:0030554 adenyl nucleotide binding 17.9487 5 yes
GO:0032559 adenyl ribonucleotide binding 17.9487 5 yes
GO:0043531 ADP binding 3.8462 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MYO6_HUMAN
GO:0048522 positive regulation of cellular process 59.6154 4 yes
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 47.4359 4 yes
GO:0080090 regulation of primary metabolic process 45.5128 4 yes
GO:0031323 regulation of cellular metabolic process 43.5897 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 43.5897 4 yes
GO:0051128 regulation of cellular component organization 43.5897 4 no
GO:0010646 regulation of cell communication 42.9487 4 no
GO:0009893 positive regulation of metabolic process 38.4615 4 yes
GO:0009966 regulation of signal transduction 36.5385 4 no
GO:0010604 positive regulation of macromolecule metabolic process 35.2564 5 yes
GO:0022607 cellular component assembly 35.2564 4 no
GO:0008104 protein localization 34.6154 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 33.9744 5 yes
GO:0006996 organelle organization 33.9744 4 no
GO:0010468 regulation of gene expression 31.4103 5 yes
GO:0031325 positive regulation of cellular metabolic process 30.7692 5 yes
GO:0051049 regulation of transport 30.1282 4 yes
GO:0016192 vesicle-mediated transport 29.4872 4 yes
GO:0009892 negative regulation of metabolic process 29.4872 4 no
GO:0051246 regulation of protein metabolic process 29.4872 5 no
GO:0009889 regulation of biosynthetic process 28.2051 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 27.5641 5 no
GO:0031326 regulation of cellular biosynthetic process 26.9231 5 yes
GO:0071702 organic substance transport 26.2821 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 25.6410 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 yes
GO:0071705 nitrogen compound transport 25.0000 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 24.3590 5 no
GO:0010647 positive regulation of cell communication 24.3590 5 no
GO:0023056 positive regulation of signaling 24.3590 4 no
GO:0007010 cytoskeleton organization 24.3590 5 no
GO:0033043 regulation of organelle organization 23.7179 5 no
GO:0010941 regulation of cell death 23.7179 4 no
GO:0051247 positive regulation of protein metabolic process 23.7179 6 no
GO:1902531 regulation of intracellular signal transduction 23.7179 5 no
GO:0048584 positive regulation of response to stimulus 23.7179 4 no
GO:0044087 regulation of cellular component biogenesis 23.7179 4 no
GO:0031324 negative regulation of cellular metabolic process 23.0769 5 no
GO:0051252 regulation of RNA metabolic process 22.4359 5 yes
GO:0051130 positive regulation of cellular component organization 22.4359 5 no
GO:0043412 macromolecule modification 22.4359 4 no
GO:0042981 regulation of apoptotic process 21.7949 6 no
GO:0043067 regulation of programmed cell death 21.7949 5 no
GO:0022603 regulation of anatomical structure morphogenesis 21.7949 4 no
GO:0015031 protein transport 21.1538 4 yes
GO:0060341 regulation of cellular localization 21.1538 4 no
GO:0036211 protein modification process 21.1538 4 no
GO:0006355 regulation of DNA-templated transcription 20.5128 6 yes
GO:1903506 regulation of nucleic acid-templated transcription 20.5128 7 yes
GO:2001141 regulation of RNA biosynthetic process 20.5128 6 yes
GO:0009967 positive regulation of signal transduction 20.5128 5 no
GO:0006897 endocytosis 19.8718 5 yes
GO:0097435 supramolecular fiber organization 17.3077 4 yes
GO:0006886 intracellular protein transport 16.0256 4 yes
GO:0009891 positive regulation of biosynthetic process 15.3846 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 15.3846 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 15.3846 6 yes
GO:0007015 actin filament organization 14.7436 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 14.1026 7 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 12.8205 6 yes
GO:0051254 positive regulation of RNA metabolic process 10.8974 6 yes
GO:0045893 positive regulation of DNA-templated transcription 9.6154 7 yes
GO:0051046 regulation of secretion 9.6154 5 yes
GO:1902680 positive regulation of RNA biosynthetic process 9.6154 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 9.6154 8 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 7.6923 8 yes
GO:0006974 cellular response to DNA damage stimulus 5.7692 4 yes
GO:0030705 cytoskeleton-dependent intracellular transport 5.1282 4 yes
GO:0030855 epithelial cell differentiation 4.4872 4 yes
GO:0051650 establishment of vesicle localization 4.4872 4 yes
GO:0030182 neuron differentiation 3.8462 4 yes
GO:0030050 vesicle transport along actin filament 2.5641 4 yes
GO:0042770 signal transduction in response to DNA damage 2.5641 4 yes
GO:0099515 actin filament-based transport 2.5641 5 yes
GO:0099518 vesicle cytoskeletal trafficking 2.5641 5 yes
GO:0007600 sensory perception 1.9231 4 yes
GO:0009913 epidermal cell differentiation 1.9231 5 yes
GO:0035315 hair cell differentiation 1.9231 5 yes
GO:0042490 mechanoreceptor differentiation 1.9231 5 yes
GO:0072331 signal transduction by p53 class mediator 1.9231 4 yes
GO:0007605 sensory perception of sound 1.2821 6 yes
GO:0030330 DNA damage response, signal transduction by p53 class mediator 1.2821 5 yes
GO:0042472 inner ear morphogenesis 1.2821 4 yes
GO:0042491 inner ear auditory receptor cell differentiation 1.2821 6 yes
GO:0050954 sensory perception of mechanical stimulus 1.2821 5 yes
GO:0060113 inner ear receptor cell differentiation 1.2821 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in MYO6_HUMAN
DOID:331 central nervous system disease 3.2051 3 no
DOID:114 heart disease 2.5641 3 no
DOID:0050155 sensory system disease 1.9231 3 yes
DOID:0050563 nonsyndromic deafness 1.9231 5 yes
DOID:0050564 autosomal dominant nonsyndromic deafness 1.9231 6 yes
DOID:2742 auditory system disease 1.9231 4 yes
DOID:0050700 cardiomyopathy 1.9231 4 no
DOID:0060036 intrinsic cardiomyopathy 1.9231 5 no
DOID:0060038 specific developmental disorder 1.9231 3 no
DOID:1059 intellectual disability 1.9231 4 no
DOID:612 primary immunodeficiency disease 1.9231 3 no
DOID:1289 neurodegenerative disease 1.9231 4 no
DOID:0050701 electroclinical syndrome 1.9231 6 no
DOID:0112202 developmental and epileptic encephalopathy 1.9231 7 no
DOID:1826 epilepsy 1.9231 5 no
DOID:936 brain disease 1.9231 4 no
DOID:0050565 autosomal recessive nonsyndromic deafness 1.2821 6 yes
DOID:0110495 autosomal recessive nonsyndromic deafness 37 1.2821 7 yes
DOID:0110552 autosomal dominant nonsyndromic deafness 22 1.2821 7 yes
DOID:2843 long QT syndrome 1.2821 6 no
DOID:0111962 combined immunodeficiency 1.2821 4 no
DOID:0050890 synucleinopathy 1.2821 5 no
DOID:0060894 early-onset Parkinsons disease 1.2821 7 no
DOID:14330 Parkinsons disease 1.2821 6 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SEPT9_HUMAN [view interactions] Low throughput no no
DAB2_HUMAN [view interactions] Low throughput no yes
TM1L2_HUMAN [view entry] [view interactions] Low throughput yes yes
TOM1_HUMAN [view interactions] Low throughput no yes
DAB1_HUMAN [view interactions] Low throughput no yes
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
GIPC1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
CFTR_HUMAN [view interactions] Low throughput no no
NUCL_HUMAN [view interactions] Low throughput no yes
LRCH3_HUMAN [view interactions] Low throughput no yes
LMTK2_HUMAN [view entry] [view interactions] Low throughput yes yes
HNRPU_HUMAN [view interactions] Low throughput no yes
DOCK7_HUMAN [view entry] [view interactions] Low throughput yes no
AP2B1_HUMAN [view entry] [view interactions] Low throughput yes yes
MYO6_HUMAN [view entry] [view interactions] Low throughput yes no
SP1_HUMAN [view interactions] Low throughput no yes
RPB1_HUMAN [view interactions] Low throughput no no
PML_HUMAN [view interactions] Low throughput no yes
SRSF2_HUMAN [view interactions] Low throughput no yes
TAXB1_HUMAN [view interactions] Low throughput no yes
CACO2_HUMAN [view interactions] Low throughput no yes
OPTN_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA2_HUMAN [view entry] [view interactions] Low throughput yes yes
AP2A1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
CLH1_HUMAN [view entry] [view interactions] Low throughput yes yes
CAZA1_HUMAN [view entry] [view interactions] Low throughput yes yes
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
CLCB_HUMAN [view entry] [view interactions] Low throughput yes yes
GIPC2_HUMAN [view interactions] Low throughput no yes
CLCA_HUMAN [view entry] [view interactions] Low throughput yes no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
NUPR1_HUMAN [view interactions] High throughput no no
CSN5_HUMAN [view interactions] High throughput no yes
F16P1_HUMAN [view interactions] High throughput no no
RU17_HUMAN [view interactions] High throughput no yes
RUXE_HUMAN [view interactions] High throughput no no
GEMI8_HUMAN [view interactions] High throughput no yes
STRAP_HUMAN [view entry] [view interactions] High throughput yes yes
RUXF_HUMAN [view interactions] High throughput no no
GEMI6_HUMAN [view interactions] High throughput no yes
GEMI2_HUMAN [view interactions] High throughput no yes
GEMI4_HUMAN [view interactions] High throughput no yes
DDX20_HUMAN [view interactions] High throughput no no
PROF2_HUMAN [view entry] [view interactions] High throughput yes yes
DZIP3_HUMAN [view interactions] High throughput no yes
MKRN2_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
ISG15_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
PCGF3_HUMAN [view interactions] High throughput no yes
ML12B_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
FGD5_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
TFR1_HUMAN [view interactions] High throughput no yes
CATB_HUMAN [view interactions] High throughput no yes
IFM1_HUMAN [view interactions] High throughput no no
CATS_HUMAN [view interactions] High throughput no no
DPP4_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
CLC4D_HUMAN [view interactions] High throughput no no
CLC4E_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOD_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
RHBT1_HUMAN [view interactions] High throughput no yes
RNF11_HUMAN [view interactions] High throughput no yes
RHBT2_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND2_HUMAN [view interactions] High throughput no no
RND3_HUMAN [view interactions] High throughput no no
F1892_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
ARL8A_HUMAN [view interactions] High throughput no no
UBP11_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
UBP25_HUMAN [view interactions] High throughput no yes
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
FA13A_HUMAN [view interactions] High throughput no yes
WRP73_HUMAN [view interactions] High throughput no no
MYL6B_HUMAN [view entry] [view interactions] High throughput yes no
ACTBL_HUMAN [view interactions] High throughput no no
RS27A_HUMAN [view entry] [view interactions] High throughput yes yes
FBX30_HUMAN [view interactions] High throughput no yes
DP13B_HUMAN [view entry] [view interactions] High throughput yes yes
FBX34_HUMAN [view interactions] High throughput no no
TMOD2_HUMAN [view entry] [view interactions] High throughput yes yes
NEB1_HUMAN [view entry] [view interactions] High throughput yes yes
DPP9_HUMAN [view interactions] High throughput no yes
CUED1_HUMAN [view interactions] High throughput no yes
DNJC2_HUMAN [view interactions] High throughput no yes
POTEI_HUMAN [view interactions] High throughput no no
G6PD_HUMAN [view entry] [view interactions] High throughput yes no
AAPK1_HUMAN [view interactions] High throughput no no
PAK2_HUMAN [view entry] [view interactions] High throughput yes no
AAKB1_HUMAN [view interactions] High throughput no yes
RD23A_HUMAN [view interactions] High throughput no yes
RD23B_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
NHLC2_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
SRRM2_HUMAN [view interactions] High throughput no yes
SH3L1_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
SH2D3_HUMAN [view interactions] High throughput no no
F120C_HUMAN [view interactions] High throughput no yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
CPSF1_HUMAN [view interactions] High throughput no no
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPC_HUMAN [view interactions] High throughput no yes
ZBT18_HUMAN [view interactions] High throughput no yes
KANK1_HUMAN [view interactions] High throughput no yes
CHK2_HUMAN [view interactions] High throughput no yes
VANG1_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
SHRM3_HUMAN [view interactions] High throughput no yes
COX15_HUMAN [view interactions] High throughput no yes
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
WRIP1_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
TRIMM_HUMAN [view interactions] High throughput no no
H2B1H_HUMAN [view interactions] High throughput no yes
LCAP_HUMAN [view interactions] High throughput no yes
CSTF3_HUMAN [view interactions] High throughput no yes
WDR33_HUMAN [view interactions] High throughput no yes
GTR1_HUMAN [view entry] [view interactions] High throughput yes no
PKP2_HUMAN [view interactions] High throughput no yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
MTCL1_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
SPB1_HUMAN [view interactions] High throughput no yes
KRI1_HUMAN [view interactions] High throughput no yes
E2F3_HUMAN [view interactions] High throughput no no
CCSE2_HUMAN [view interactions] High throughput no yes
HMGA2_HUMAN [view interactions] High throughput no yes
SEM4C_HUMAN [view entry] [view interactions] High throughput yes no
PPR3C_HUMAN [view interactions] High throughput no yes
FLOT2_HUMAN [view entry] [view interactions] High throughput yes yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
LTV1_HUMAN [view interactions] High throughput no yes
AKA11_HUMAN [view interactions] High throughput no yes
DDX3Y_HUMAN [view interactions] High throughput no yes
IPO8_HUMAN [view interactions] High throughput no no
XRCC5_HUMAN [view interactions] High throughput no yes
TOP2A_HUMAN [view interactions] High throughput no no
WRN_HUMAN [view interactions] High throughput no yes
MOONR_HUMAN [view interactions] High throughput no yes
TRI41_HUMAN [view interactions] High throughput no yes
TRA2B_HUMAN [view interactions] High throughput no yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
YETS2_HUMAN [view interactions] High throughput no no
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
SI1L1_HUMAN [view entry] [view interactions] High throughput yes yes
RS6_HUMAN [view entry] [view interactions] High throughput yes yes
PCM1_HUMAN [view interactions] High throughput no yes
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
OFD1_HUMAN [view interactions] High throughput no yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
RB6I2_HUMAN [view entry] [view interactions] High throughput yes yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
ZN638_HUMAN [view interactions] High throughput no yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
KIRR1_HUMAN [view interactions] High throughput no no
RLA0_HUMAN [view entry] [view interactions] High throughput yes yes
MAGI1_HUMAN [view interactions] High throughput no no
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
NSF1C_HUMAN [view entry] [view interactions] High throughput yes yes
RL7_HUMAN [view entry] [view interactions] High throughput yes yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
RPA1_HUMAN [view interactions] High throughput no yes
NOG2_HUMAN [view interactions] High throughput no yes
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
BNIP2_HUMAN [view interactions] High throughput no yes
PDIA1_HUMAN [view interactions] High throughput no yes
SURF6_HUMAN [view interactions] High throughput no yes
NOL8_HUMAN [view interactions] High throughput no yes
PP6R1_HUMAN [view interactions] High throughput no no
LRCH1_HUMAN [view interactions] High throughput no yes
PHLB2_HUMAN [view interactions] High throughput no yes
DOCK8_HUMAN [view interactions] High throughput no yes
ZFYV9_HUMAN [view interactions] High throughput no yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
SYNJ1_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
SYNRG_HUMAN [view interactions] High throughput no yes
PAAT_HUMAN [view interactions] High throughput no yes
DOCK6_HUMAN [view interactions] High throughput no yes
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
CLCN7_HUMAN [view interactions] High throughput no yes
DDX3X_HUMAN [view entry] [view interactions] High throughput yes yes
TPGS1_HUMAN [view interactions] High throughput no no
DDX17_HUMAN [view entry] [view interactions] High throughput yes yes
AP2S1_HUMAN [view entry] [view interactions] High throughput yes no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
EPN2_HUMAN [view entry] [view interactions] High throughput yes yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
ANR28_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
EP15R_HUMAN [view entry] [view interactions] High throughput yes yes
DAPK1_HUMAN [view entry] [view interactions] High throughput yes yes
LRC49_HUMAN [view interactions] High throughput no no
IRF8_HUMAN [view interactions] High throughput no no
ODB2_HUMAN [view entry] [view interactions] High throughput yes yes
PAX7_HUMAN [view interactions] High throughput no no
ANR40_HUMAN [view interactions] High throughput no yes
ZIC3_HUMAN [view interactions] High throughput no no
SAHH_HUMAN [view entry] [view interactions] High throughput yes yes
ELF3_HUMAN [view interactions] High throughput no no
GGA3_HUMAN [view entry] [view interactions] High throughput yes yes
EPHAA_HUMAN [view interactions] High throughput no yes
FCHO2_HUMAN [view interactions] High throughput no yes
LZTS2_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
LRCH2_HUMAN [view interactions] High throughput no no
BCAR1_HUMAN [view interactions] High throughput no yes
PARP4_HUMAN [view interactions] High throughput no yes
PKHA7_HUMAN [view interactions] High throughput no yes
ZFY16_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
ITSN1_HUMAN [view entry] [view interactions] High throughput yes yes
BMI1_HUMAN [view interactions] High throughput no yes
ITSN2_HUMAN [view entry] [view interactions] High throughput yes yes
F1711_HUMAN [view entry] [view interactions] High throughput yes yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
GULP1_HUMAN [view interactions] High throughput no no
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
DP13A_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
TXNL1_HUMAN [view entry] [view interactions] High throughput yes yes
APC_HUMAN [view entry] [view interactions] High throughput yes no
FMNL3_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
FHI1A_HUMAN [view interactions] High throughput no yes
IKKE_HUMAN [view interactions] High throughput no yes
STRN3_HUMAN [view interactions] High throughput no yes
NEMO_HUMAN [view interactions] High throughput no yes
HOOK3_HUMAN [view entry] [view interactions] High throughput yes yes
M3K3_HUMAN [view interactions] High throughput no no
ZNF24_HUMAN [view interactions] High throughput no yes
RIPK3_HUMAN [view interactions] High throughput no no
LRCH4_HUMAN [view interactions] High throughput no no
TNR1A_HUMAN [view interactions] High throughput no yes
CP131_HUMAN [view interactions] High throughput no no
TNR1B_HUMAN [view interactions] High throughput no no
BMP2K_HUMAN [view interactions] High throughput no yes
SMN_HUMAN [view interactions] High throughput no yes
SI1L3_HUMAN [view interactions] High throughput no yes
CSAG1_HUMAN [view interactions] High throughput no no
PTH2_HUMAN [view interactions] High throughput no yes
RFFL_HUMAN [view interactions] High throughput no yes
DBLOH_HUMAN [view interactions] High throughput no no
RN183_HUMAN [view interactions] High throughput no no
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
DNJC5_HUMAN [view interactions] High throughput no yes
PSA1_HUMAN [view interactions] High throughput no yes
B3GA1_HUMAN [view interactions] High throughput no yes
PLRKT_HUMAN [view interactions] High throughput no yes
CAV1_HUMAN [view interactions] High throughput no no
FOS_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
FOXL1_HUMAN [view interactions] High throughput no no
CXD3_HUMAN [view interactions] High throughput no no
STAT1_HUMAN [view entry] [view interactions] High throughput yes no
LAMP2_HUMAN [view interactions] High throughput no yes
EPHA5_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR3_HUMAN [view interactions] High throughput no yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
FGFR4_HUMAN [view interactions] High throughput no no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
PTN11_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK2_HUMAN [view entry] [view interactions] High throughput yes yes
RAB9A_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
STX6_HUMAN [view interactions] High throughput no yes
PGFRA_HUMAN [view interactions] High throughput no no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
NAA40_HUMAN [view interactions] High throughput no no
TMPS2_HUMAN [view interactions] High throughput no no
CATL1_HUMAN [view interactions] High throughput no yes
WBP2_HUMAN [view interactions] High throughput no yes
FURIN_HUMAN [view interactions] High throughput no yes
RPOM_HUMAN [view interactions] High throughput no yes
TM11B_HUMAN [view interactions] High throughput no no
RNF43_HUMAN [view interactions] High throughput no yes
FBX25_HUMAN [view interactions] High throughput no no
KCNQ2_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
PAN2_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
ABCE1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
CAZA2_HUMAN [view entry] [view interactions] High throughput yes yes
CDK2_HUMAN [view interactions] High throughput no yes
DREB_HUMAN [view entry] [view interactions] High throughput yes yes
FLNA_HUMAN [view entry] [view interactions] High throughput yes no
GAK_HUMAN [view entry] [view interactions] High throughput yes yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
PICAL_HUMAN [view entry] [view interactions] High throughput yes yes
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
GTSE1_HUMAN [view interactions] High throughput no no
ANLN_HUMAN [view interactions] High throughput no yes
MYO5C_HUMAN [view entry] [view interactions] High throughput yes yes
MYO19_HUMAN [view interactions] High throughput no yes
MY18A_HUMAN [view entry] [view interactions] High throughput yes yes
CD2AP_HUMAN [view interactions] High throughput no no
ITA5_HUMAN [view entry] [view interactions] High throughput yes no
MYO1C_HUMAN [view entry] [view interactions] High throughput yes yes
TPM1_HUMAN [view entry] [view interactions] High throughput yes no
TMOD3_HUMAN [view interactions] High throughput no yes
CALL3_HUMAN [view interactions] High throughput no yes
MYH10_HUMAN [view entry] [view interactions] High throughput yes yes
UBXN1_HUMAN [view interactions] High throughput no no
RN126_HUMAN [view interactions] High throughput no yes
SC16A_HUMAN [view interactions] High throughput no yes
AP2A2_HUMAN [view entry] [view interactions] High throughput yes yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
EPN4_HUMAN [view interactions] High throughput no yes
P3C2A_HUMAN [view interactions] High throughput no yes
EPS15_HUMAN [view entry] [view interactions] High throughput yes yes
REPS2_HUMAN [view entry] [view interactions] High throughput yes no
COPB2_HUMAN [view entry] [view interactions] High throughput yes yes
DDB1_HUMAN [view interactions] High throughput no yes
SYEP_HUMAN [view interactions] High throughput no yes
DCAF1_HUMAN [view interactions] High throughput no yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
GTPB4_HUMAN [view interactions] High throughput no yes
ARHGC_HUMAN [view interactions] High throughput no yes
YTDC2_HUMAN [view interactions] High throughput no no
DCTN2_HUMAN [view entry] [view interactions] High throughput yes yes
GELS_HUMAN [view entry] [view interactions] High throughput yes no
REPS1_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
DX39B_HUMAN [view interactions] High throughput no no
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
SYLC_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
RMD5A_HUMAN [view interactions] High throughput no yes
LAP2A_HUMAN [view interactions] High throughput no yes
TNFA_HUMAN [view interactions] High throughput no no
SH3B4_HUMAN [view interactions] High throughput no yes
CAR10_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
ACTC_HUMAN [view interactions] High throughput no no
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
APEX1_HUMAN [view interactions] High throughput no yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
LRC31_HUMAN [view interactions] High throughput no no
CTNB1_HUMAN [view entry] [view interactions] Computational yes yes
CTND1_HUMAN [view entry] [view interactions] Computational yes no
CTNA1_HUMAN [view entry] [view interactions] Computational yes yes
MDM2_HUMAN [view interactions] Computational no yes
MYL6_HUMAN [view entry] [view interactions] Computational yes no
TPRN_HUMAN [view interactions] Computational no yes
RAC3_HUMAN [view entry] [view interactions] Computational yes no
KCC2D_HUMAN [view entry] [view interactions] Computational yes yes
CCG8_HUMAN [view entry] [view interactions] Computational yes no
OTOF_HUMAN [view interactions] Computational no yes
VINC_HUMAN [view entry] [view interactions] Computational yes no
RL40_HUMAN [view entry] [view interactions] Computational yes yes
CCG3_HUMAN [view entry] [view interactions] Computational yes no
GRIA4_HUMAN [view entry] [view interactions] Computational yes no
PDLI4_HUMAN [view entry] [view interactions] Computational yes yes
PAK3_HUMAN [view entry] [view interactions] Computational yes no
MYO9A_HUMAN [view entry] [view interactions] Computational yes yes
PDLI2_HUMAN [view interactions] Computational no no
MYO1A_HUMAN [view interactions] Computational no no
CCG2_HUMAN [view entry] [view interactions] Computational yes no
E41L1_HUMAN [view entry] [view interactions] Computational yes yes
GRIA3_HUMAN [view entry] [view interactions] Computational yes yes
MY18B_HUMAN [view interactions] Computational no no
GRIA1_HUMAN [view entry] [view interactions] Computational yes yes
AKAP5_HUMAN [view entry] [view interactions] Computational yes yes
CCG4_HUMAN [view entry] [view interactions] Computational yes no
KCC2B_HUMAN [view entry] [view interactions] Computational yes yes