EPN2_HUMAN
Plays a role in the formation of clathrin-coated invaginations and endocytosis. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001148 | LIG_EH_1 | LIG | 536 | 540 | - |
ELMI001149 | LIG_EH_1 | LIG | 551 | 555 | - |
ELMI001150 | LIG_EH_1 | LIG | 636 | 640 | - |
ELMI001210 | TRG_AP2beta_CARGO_1 | TRG | 456 | 465 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in EPN2_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 24.3902 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 24.3902 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 24.3902 | 4 | no |
GO:0046872 | metal ion binding | 21.9512 | 4 | no |
GO:0045296 | cadherin binding | 19.5122 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in EPN2_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 53.6585 | 4 | yes |
GO:0008104 | protein localization | 53.6585 | 4 | no |
GO:0048523 | negative regulation of cellular process | 51.2195 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 51.2195 | 4 | no |
GO:0016192 | vesicle-mediated transport | 48.7805 | 4 | yes |
GO:0071702 | organic substance transport | 48.7805 | 4 | no |
GO:0071705 | nitrogen compound transport | 48.7805 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 48.7805 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 46.3415 | 4 | no |
GO:0006897 | endocytosis | 43.9024 | 5 | yes |
GO:0015031 | protein transport | 43.9024 | 4 | no |
GO:0010646 | regulation of cell communication | 41.4634 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 41.4634 | 4 | no |
GO:0051128 | regulation of cellular component organization | 41.4634 | 4 | no |
GO:0006996 | organelle organization | 39.0244 | 4 | no |
GO:0009966 | regulation of signal transduction | 36.5854 | 4 | yes |
GO:0006886 | intracellular protein transport | 36.5854 | 4 | no |
GO:0022607 | cellular component assembly | 36.5854 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 34.1463 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 34.1463 | 5 | no |
GO:0009889 | regulation of biosynthetic process | 31.7073 | 4 | no |
GO:0010468 | regulation of gene expression | 31.7073 | 5 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 31.7073 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 31.7073 | 5 | no |
GO:0006898 | receptor-mediated endocytosis | 31.7073 | 6 | no |
GO:0031325 | positive regulation of cellular metabolic process | 29.2683 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 29.2683 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 29.2683 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 26.8293 | 5 | no |
GO:0072583 | clathrin-dependent endocytosis | 26.8293 | 7 | no |
GO:0051246 | regulation of protein metabolic process | 26.8293 | 5 | no |
GO:0010941 | regulation of cell death | 26.8293 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 24.3902 | 4 | yes |
GO:0006355 | regulation of DNA-templated transcription | 24.3902 | 6 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.3902 | 5 | no |
GO:0051049 | regulation of transport | 24.3902 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 24.3902 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 24.3902 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 24.3902 | 6 | no |
GO:0043933 | protein-containing complex organization | 24.3902 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 24.3902 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 24.3902 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 21.9512 | 5 | yes |
GO:0010647 | positive regulation of cell communication | 21.9512 | 5 | yes |
GO:0023056 | positive regulation of signaling | 21.9512 | 4 | yes |
GO:0009891 | positive regulation of biosynthetic process | 21.9512 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.9512 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 21.9512 | 6 | no |
GO:0032880 | regulation of protein localization | 21.9512 | 5 | no |
GO:0060341 | regulation of cellular localization | 21.9512 | 4 | no |
GO:0065003 | protein-containing complex assembly | 21.9512 | 5 | no |
GO:0042981 | regulation of apoptotic process | 21.9512 | 6 | no |
GO:0043067 | regulation of programmed cell death | 21.9512 | 5 | no |
GO:0010648 | negative regulation of cell communication | 14.6341 | 5 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 14.6341 | 4 | yes |
GO:0023057 | negative regulation of signaling | 14.6341 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 12.1951 | 5 | yes |
GO:0048585 | negative regulation of response to stimulus | 12.1951 | 4 | yes |
GO:2000026 | regulation of multicellular organismal development | 12.1951 | 4 | yes |
GO:0051093 | negative regulation of developmental process | 9.7561 | 4 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 9.7561 | 4 | yes |
GO:0008593 | regulation of Notch signaling pathway | 4.8780 | 5 | yes |
GO:0045765 | regulation of angiogenesis | 4.8780 | 5 | yes |
GO:1901342 | regulation of vasculature development | 4.8780 | 5 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
UBQL2_HUMAN | [view interactions] | Low throughput | no | yes |
VGFR3_HUMAN | [view interactions] | Low throughput | no | yes |
RBP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EPS15_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CLH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AP2A2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TBA1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EED_HUMAN | [view interactions] | High throughput | no | yes |
EPN3_HUMAN | [view interactions] | High throughput | no | no |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
BACD3_HUMAN | [view interactions] | High throughput | no | yes |
1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBM47_HUMAN | [view interactions] | High throughput | no | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHG18_HUMAN | [view interactions] | High throughput | no | yes |
CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H2A2A_HUMAN | [view interactions] | High throughput | no | yes |
RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H2B1C_HUMAN | [view interactions] | High throughput | no | yes |
H1X_HUMAN | [view interactions] | High throughput | no | yes |
RAD50_HUMAN | [view interactions] | High throughput | no | yes |
SMCA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NSD2_HUMAN | [view interactions] | High throughput | no | yes |
EP15R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
RN183_HUMAN | [view interactions] | High throughput | no | no |
CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXD3_HUMAN | [view interactions] | High throughput | no | no |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STX6_HUMAN | [view interactions] | High throughput | no | yes |
STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DPP4_HUMAN | [view interactions] | High throughput | no | no |
ACE2_HUMAN | [view interactions] | High throughput | no | no |
F1892_HUMAN | [view interactions] | High throughput | no | yes |
GTSE1_HUMAN | [view interactions] | High throughput | no | no |
1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEUL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
PICAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMM17_HUMAN | [view interactions] | High throughput | no | yes |
TGON2_HUMAN | [view interactions] | High throughput | no | yes |
LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
EPHA2_HUMAN | [view interactions] | High throughput | no | no |
FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
FGFR4_HUMAN | [view interactions] | High throughput | no | no |
FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
RAB3I_HUMAN | [view interactions] | High throughput | no | no |
ITSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
APOE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WBP2_HUMAN | [view interactions] | High throughput | no | yes |
F168A_HUMAN | [view interactions] | High throughput | no | yes |
TRIM1_HUMAN | [view interactions] | High throughput | no | no |
TXLNA_HUMAN | [view interactions] | High throughput | no | yes |
CDIP1_HUMAN | [view interactions] | High throughput | no | yes |
TRI18_HUMAN | [view interactions] | High throughput | no | no |
EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARRD2_HUMAN | [view interactions] | High throughput | no | no |
RNF8_HUMAN | [view interactions] | High throughput | no | yes |
ARRD3_HUMAN | [view interactions] | High throughput | no | no |
TRI23_HUMAN | [view interactions] | High throughput | no | yes |
PKHB2_HUMAN | [view interactions] | High throughput | no | yes |
TRI62_HUMAN | [view interactions] | High throughput | no | no |
MAR1_HUMAN | [view interactions] | High throughput | no | no |
PMEPA_HUMAN | [view interactions] | High throughput | no | no |
ATX1_HUMAN | [view interactions] | High throughput | no | yes |
SPART_HUMAN | [view interactions] | High throughput | no | yes |
LFG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
PP4P1_HUMAN | [view interactions] | High throughput | no | yes |
WBP1L_HUMAN | [view interactions] | High throughput | no | yes |
SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
THOP1_HUMAN | [view interactions] | High throughput | no | yes |
DAZP2_HUMAN | [view interactions] | High throughput | no | no |
FANCM_HUMAN | [view interactions] | High throughput | no | no |
LITAF_HUMAN | [view interactions] | High throughput | no | yes |
ARRD1_HUMAN | [view interactions] | High throughput | no | yes |
RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI26_HUMAN | [view interactions] | High throughput | no | yes |
WBP1_HUMAN | [view interactions] | High throughput | no | yes |
UBB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VGFR2_HUMAN | [view interactions] | Computational | no | no |
AP2M1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ITSN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FCHO2_HUMAN | [view interactions] | Computational | no | yes |
AP2A1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CLH2_HUMAN | [view interactions] | Computational | no | no |
GAK_HUMAN | [view entry] [view interactions] | Computational | yes | yes |