MYL6B_HUMAN
Evidence for PS localization
Functions
Regulatory light chain of myosin. Does not bind calcium. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MYL6B_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 46.1538 | 4 | no |
| GO:0000166 | nucleotide binding | 43.5897 | 4 | no |
| GO:0017076 | purine nucleotide binding | 43.5897 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 43.5897 | 4 | no |
| GO:0043169 | cation binding | 41.0256 | 4 | yes |
| GO:0046872 | metal ion binding | 41.0256 | 5 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 41.0256 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 33.3333 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 33.3333 | 5 | no |
| GO:0005524 | ATP binding | 30.7692 | 5 | no |
| GO:0003779 | actin binding | 30.7692 | 4 | no |
| GO:0019900 | kinase binding | 28.2051 | 4 | no |
| GO:0019901 | protein kinase binding | 28.2051 | 5 | no |
| GO:0005509 | calcium ion binding | 20.5128 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MYL6B_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 64.1026 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 56.4103 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 53.8462 | 4 | no |
| GO:0006996 | organelle organization | 48.7179 | 4 | no |
| GO:0010646 | regulation of cell communication | 48.7179 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 48.7179 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.7179 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 46.1538 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 43.5897 | 4 | no |
| GO:0009966 | regulation of signal transduction | 43.5897 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.5897 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 41.0256 | 5 | no |
| GO:0007010 | cytoskeleton organization | 38.4615 | 5 | no |
| GO:0022607 | cellular component assembly | 35.8974 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 35.8974 | 5 | no |
| GO:0008104 | protein localization | 33.3333 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 33.3333 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.3333 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.3333 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 33.3333 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.7692 | 4 | no |
| GO:0141124 | intracellular signaling cassette | 30.7692 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 30.7692 | 4 | no |
| GO:0051726 | regulation of cell cycle | 30.7692 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.2051 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.2051 | 5 | no |
| GO:0031399 | regulation of protein modification process | 28.2051 | 6 | no |
| GO:0043933 | protein-containing complex organization | 28.2051 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.2051 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.2051 | 5 | no |
| GO:0051049 | regulation of transport | 28.2051 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.6410 | 7 | no |
| GO:0042981 | regulation of apoptotic process | 25.6410 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 25.6410 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.6410 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.6410 | 6 | no |
| GO:0010564 | regulation of cell cycle process | 25.6410 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 25.6410 | 4 | no |
| GO:0033043 | regulation of organelle organization | 25.6410 | 5 | no |
| GO:0030030 | cell projection organization | 23.0769 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.0769 | 7 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.0769 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.0769 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 23.0769 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.0769 | 6 | no |
| GO:0023056 | positive regulation of signaling | 23.0769 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.0769 | 6 | no |
| GO:0031401 | positive regulation of protein modification process | 23.0769 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 23.0769 | 7 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.0769 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 23.0769 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.0769 | 5 | no |
| GO:0071310 | cellular response to organic substance | 23.0769 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 23.0769 | 4 | no |
| GO:0007264 | small GTPase-mediated signal transduction | 20.5128 | 5 | no |
| GO:0032880 | regulation of protein localization | 20.5128 | 5 | no |
| GO:0060341 | regulation of cellular localization | 20.5128 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 20.5128 | 8 | no |
| GO:0009967 | positive regulation of signal transduction | 20.5128 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 20.5128 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 20.5128 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.5128 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 20.5128 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 20.5128 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.5128 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 20.5128 | 4 | no |
| GO:2000145 | regulation of cell motility | 20.5128 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 20.5128 | 5 | no |
| GO:0051050 | positive regulation of transport | 20.5128 | 4 | no |
| GO:0007015 | actin filament organization | 20.5128 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 20.5128 | 6 | no |
| GO:0060537 | muscle tissue development | 12.8205 | 4 | yes |
| GO:0006936 | muscle contraction | 10.2564 | 4 | yes |
| GO:0007519 | skeletal muscle tissue development | 10.2564 | 5 | yes |
| GO:0030049 | muscle filament sliding | 7.6923 | 6 | yes |
| GO:0033275 | actin-myosin filament sliding | 7.6923 | 5 | yes |
| GO:0070252 | actin-mediated cell contraction | 7.6923 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MDM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| MYL6B_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| IQGA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK3_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| FOS_HUMAN | [view interactions] | High throughput | no | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHI1B_HUMAN | [view interactions] | High throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFE2_HUMAN | [view interactions] | High throughput | no | no |
| SP1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| PAN2_HUMAN | [view interactions] | High throughput | no | no |
| CEP57_HUMAN | [view interactions] | High throughput | no | yes |
| CEP76_HUMAN | [view interactions] | High throughput | no | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| R144A_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT7B_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO9A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG8_HUMAN | [view interactions] | High throughput | no | yes |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTX3_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ML12A_HUMAN | [view interactions] | High throughput | no | no |
| MYL9_HUMAN | [view interactions] | High throughput | no | no |
| IQGA3_HUMAN | [view interactions] | High throughput | no | no |
| MYH14_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| SMAP_HUMAN | [view interactions] | High throughput | no | yes |
| EIPR1_HUMAN | [view interactions] | High throughput | no | yes |
| EI2BE_HUMAN | [view interactions] | High throughput | no | yes |
| IRF3_HUMAN | [view interactions] | High throughput | no | yes |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| FOXO1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP46_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| ML12B_HUMAN | [view interactions] | High throughput | no | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SP17_HUMAN | [view interactions] | High throughput | no | no |
| MYO9B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| SIM43_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| DUX4_HUMAN | [view interactions] | High throughput | no | no |
| ATF3_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |