Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MYO9A_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating its GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in MYO9A_HUMAN
GO:0017076 purine nucleotide binding 42.8571 4 yes
GO:0032555 purine ribonucleotide binding 38.0952 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 38.0952 4 yes
GO:0030554 adenyl nucleotide binding 28.5714 5 yes
GO:0046872 metal ion binding 28.5714 4 yes
GO:0003779 actin binding 23.8095 4 yes
GO:0005524 ATP binding 23.8095 5 yes
GO:0032559 adenyl ribonucleotide binding 23.8095 5 yes
GO:0003723 RNA binding 23.8095 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in MYO9A_HUMAN
GO:0022607 cellular component assembly 52.3810 4 yes
GO:0060255 regulation of macromolecule metabolic process 47.6190 4 no
GO:0006996 organelle organization 42.8571 4 no
GO:0031323 regulation of cellular metabolic process 42.8571 4 no
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0051171 regulation of nitrogen compound metabolic process 42.8571 4 no
GO:0080090 regulation of primary metabolic process 42.8571 4 no
GO:0048523 negative regulation of cellular process 42.8571 4 no
GO:0051128 regulation of cellular component organization 38.0952 4 yes
GO:0010468 regulation of gene expression 38.0952 5 no
GO:0010646 regulation of cell communication 33.3333 4 yes
GO:0043933 protein-containing complex organization 33.3333 4 no
GO:0051049 regulation of transport 33.3333 4 no
GO:0009889 regulation of biosynthetic process 33.3333 4 no
GO:0010556 regulation of macromolecule biosynthetic process 33.3333 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 33.3333 5 no
GO:0031326 regulation of cellular biosynthetic process 33.3333 5 no
GO:0007010 cytoskeleton organization 33.3333 5 no
GO:0009966 regulation of signal transduction 28.5714 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 28.5714 4 yes
GO:0034330 cell junction organization 28.5714 4 yes
GO:0043085 positive regulation of catalytic activity 28.5714 4 yes
GO:1902531 regulation of intracellular signal transduction 28.5714 5 yes
GO:1901701 cellular response to oxygen-containing compound 28.5714 4 no
GO:0006355 regulation of DNA-templated transcription 28.5714 6 no
GO:0008104 protein localization 28.5714 4 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0051252 regulation of RNA metabolic process 28.5714 5 no
GO:1903506 regulation of nucleic acid-templated transcription 28.5714 7 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0045595 regulation of cell differentiation 28.5714 4 no
GO:0022604 regulation of cell morphogenesis 23.8095 5 yes
GO:0031344 regulation of cell projection organization 23.8095 5 yes
GO:0051336 regulation of hydrolase activity 23.8095 4 yes
GO:0010243 response to organonitrogen compound 23.8095 4 no
GO:0065003 protein-containing complex assembly 23.8095 5 no
GO:0006357 regulation of transcription by RNA polymerase II 23.8095 7 no
GO:0007015 actin filament organization 23.8095 5 no
GO:0031325 positive regulation of cellular metabolic process 23.8095 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 23.8095 5 no
GO:0071702 organic substance transport 23.8095 4 no
GO:0071705 nitrogen compound transport 23.8095 4 no
GO:0097435 supramolecular fiber organization 23.8095 4 no
GO:0043412 macromolecule modification 23.8095 4 no
GO:0032956 regulation of actin cytoskeleton organization 23.8095 5 no
GO:0032970 regulation of actin filament-based process 23.8095 4 no
GO:0033043 regulation of organelle organization 23.8095 5 no
GO:0051493 regulation of cytoskeleton organization 23.8095 6 no
GO:2000145 regulation of cell motility 23.8095 4 no
GO:0006796 phosphate-containing compound metabolic process 23.8095 4 no
GO:0019220 regulation of phosphate metabolic process 23.8095 6 no
GO:0030030 cell projection organization 23.8095 4 no
GO:0042127 regulation of cell population proliferation 23.8095 4 no
GO:0042325 regulation of phosphorylation 23.8095 7 no
GO:0051174 regulation of phosphorus metabolic process 23.8095 5 no
GO:0051246 regulation of protein metabolic process 23.8095 5 no
GO:0071310 cellular response to organic substance 23.8095 4 no
GO:0030855 epithelial cell differentiation 19.0476 4 yes
GO:0034329 cell junction assembly 19.0476 5 yes
GO:0051345 positive regulation of hydrolase activity 19.0476 5 yes
GO:0007600 sensory perception 14.2857 4 yes
GO:0030859 polarized epithelial cell differentiation 14.2857 5 yes
GO:0035088 establishment or maintenance of apical/basal cell polarity 14.2857 4 yes
GO:0035089 establishment of apical/basal cell polarity 14.2857 5 yes
GO:0043087 regulation of GTPase activity 14.2857 5 yes
GO:0043547 positive regulation of GTPase activity 14.2857 6 yes
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 14.2857 5 yes
GO:0045198 establishment of epithelial cell apical/basal polarity 14.2857 5 yes
GO:0051056 regulation of small GTPase mediated signal transduction 14.2857 6 yes
GO:0061162 establishment of monopolar cell polarity 14.2857 4 yes
GO:0090162 establishment of epithelial cell polarity 14.2857 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TRPM7_HUMAN [view interactions] High throughput no no
NAA10_HUMAN [view interactions] High throughput no yes
IMDH2_HUMAN [view interactions] High throughput no yes
UN45A_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
NUP98_HUMAN [view interactions] High throughput no no
ATP5H_HUMAN [view interactions] High throughput no yes
KTN1_HUMAN [view entry] [view interactions] High throughput yes yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
MYZAP_HUMAN [view interactions] High throughput no yes
GRL1A_HUMAN [view interactions] High throughput no no
MTR1A_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
IKBB_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
PCM1_HUMAN [view interactions] High throughput no yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
JADE2_HUMAN [view interactions] High throughput no yes
SKAP1_HUMAN [view interactions] High throughput no no
MCM2_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
DQX1_HUMAN [view interactions] High throughput no no
CDC16_HUMAN [view interactions] High throughput no yes
LZTS2_HUMAN [view interactions] High throughput no no
TMOD4_HUMAN [view interactions] High throughput no no
CNDH2_HUMAN [view interactions] High throughput no no
KAD9_HUMAN [view interactions] High throughput no yes
BPNT1_HUMAN [view interactions] High throughput no yes
CRYL1_HUMAN [view interactions] High throughput no yes
P4HA2_HUMAN [view interactions] High throughput no no
DNAI7_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
APEX1_HUMAN [view interactions] High throughput no yes
BRD7_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
RTRAF_HUMAN [view interactions] High throughput no yes
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
FUBP3_HUMAN [view interactions] High throughput no yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
CH10_HUMAN [view interactions] High throughput no yes
RT17_HUMAN [view interactions] High throughput no yes
MYL6B_HUMAN [view entry] [view interactions] High throughput yes no
NHP2_HUMAN [view interactions] High throughput no yes
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
RUXE_HUMAN [view interactions] High throughput no no
CHM4C_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
TRI52_HUMAN [view interactions] High throughput no yes
TTYH1_HUMAN [view entry] [view interactions] High throughput yes no
NEK10_HUMAN [view interactions] High throughput no no
DKK3_HUMAN [view interactions] High throughput no yes
CAN2_HUMAN [view interactions] High throughput no no
ACRBP_HUMAN [view interactions] High throughput no no
PNMA2_HUMAN [view interactions] High throughput no yes
KRT38_HUMAN [view interactions] High throughput no no
K22E_HUMAN [view interactions] High throughput no no
MR1L1_HUMAN [view interactions] High throughput no no
TBC15_HUMAN [view interactions] High throughput no yes
LURA1_HUMAN [view interactions] High throughput no yes
COPT1_HUMAN [view interactions] High throughput no no
ABTB2_HUMAN [view interactions] High throughput no yes
GALD1_HUMAN [view interactions] High throughput no yes
KCNA2_HUMAN [view entry] [view interactions] High throughput yes yes
GSDMC_HUMAN [view interactions] High throughput no no
LRAD1_HUMAN [view interactions] High throughput no no
K1C40_HUMAN [view interactions] High throughput no no
CREB3_HUMAN [view interactions] High throughput no no
UBXN6_HUMAN [view entry] [view interactions] High throughput yes yes
SAMD3_HUMAN [view interactions] High throughput no no
RGF1A_HUMAN [view interactions] High throughput no yes
ZNRD2_HUMAN [view interactions] High throughput no yes
SF3B3_HUMAN [view interactions] High throughput no yes
MAGA9_HUMAN [view interactions] High throughput no no
NGN3_HUMAN [view interactions] High throughput no no
KCNA3_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOV_HUMAN [view interactions] High throughput no no
IER5_HUMAN [view interactions] High throughput no yes
SETD2_HUMAN [view interactions] High throughput no yes
CE152_HUMAN [view interactions] High throughput no yes
PROF1_HUMAN [view entry] [view interactions] High throughput yes yes
CRK_HUMAN [view entry] [view interactions] High throughput yes no
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
2ABB_HUMAN [view interactions] High throughput no yes
MY18B_HUMAN [view interactions] Computational no no
MYO6_HUMAN [view entry] [view interactions] Computational yes no