Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MYO9A_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating its GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in MYO9A_HUMAN
GO:0043168 anion binding 35.7143 4 yes
GO:0000166 nucleotide binding 28.5714 4 yes
GO:0017076 purine nucleotide binding 28.5714 5 yes
GO:0032555 purine ribonucleotide binding 28.5714 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 28.5714 4 yes
GO:0003723 RNA binding 28.5714 4 no
GO:0043169 cation binding 25.0000 4 yes
GO:0046872 metal ion binding 25.0000 5 yes
GO:0045296 cadherin binding 25.0000 4 no
GO:0019900 kinase binding 25.0000 4 no
GO:0019901 protein kinase binding 25.0000 5 no
GO:0003779 actin binding 17.8571 4 yes
GO:0005524 ATP binding 17.8571 5 yes
GO:0030554 adenyl nucleotide binding 17.8571 6 yes
GO:0032559 adenyl ribonucleotide binding 17.8571 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MYO9A_HUMAN
GO:0060255 regulation of macromolecule metabolic process 60.7143 4 no
GO:0080090 regulation of primary metabolic process 57.1429 4 no
GO:0031323 regulation of cellular metabolic process 53.5714 4 no
GO:0048523 negative regulation of cellular process 53.5714 4 no
GO:0048522 positive regulation of cellular process 50.0000 4 no
GO:0010646 regulation of cell communication 46.4286 4 yes
GO:0051128 regulation of cellular component organization 46.4286 4 yes
GO:0022607 cellular component assembly 42.8571 4 yes
GO:0008104 protein localization 42.8571 4 no
GO:0009889 regulation of biosynthetic process 42.8571 4 no
GO:0010468 regulation of gene expression 42.8571 6 no
GO:0010556 regulation of macromolecule biosynthetic process 42.8571 5 no
GO:0031326 regulation of cellular biosynthetic process 42.8571 5 no
GO:0009966 regulation of signal transduction 35.7143 4 yes
GO:0051246 regulation of protein metabolic process 35.7143 5 no
GO:0006996 organelle organization 32.1429 4 no
GO:0009892 negative regulation of metabolic process 32.1429 4 no
GO:0009893 positive regulation of metabolic process 32.1429 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 32.1429 5 no
GO:0019220 regulation of phosphate metabolic process 32.1429 6 no
GO:0042981 regulation of apoptotic process 32.1429 5 no
GO:0043067 regulation of programmed cell death 32.1429 4 no
GO:0051174 regulation of phosphorus metabolic process 32.1429 5 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 yes
GO:0006355 regulation of DNA-templated transcription 28.5714 7 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0010605 negative regulation of macromolecule metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0045595 regulation of cell differentiation 28.5714 4 no
GO:0051252 regulation of RNA metabolic process 28.5714 5 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0051049 regulation of transport 28.5714 4 no
GO:0010648 negative regulation of cell communication 25.0000 5 no
GO:0023057 negative regulation of signaling 25.0000 4 no
GO:0031325 positive regulation of cellular metabolic process 25.0000 5 no
GO:0042127 regulation of cell population proliferation 25.0000 4 no
GO:0043933 protein-containing complex organization 25.0000 4 no
GO:0141124 intracellular signaling cassette 25.0000 4 no
GO:1901701 cellular response to oxygen-containing compound 25.0000 4 no
GO:0031344 regulation of cell projection organization 21.4286 5 yes
GO:0034330 cell junction organization 21.4286 4 yes
GO:0009891 positive regulation of biosynthetic process 21.4286 5 no
GO:0009968 negative regulation of signal transduction 21.4286 5 no
GO:0031328 positive regulation of cellular biosynthetic process 21.4286 6 no
GO:0043066 negative regulation of apoptotic process 21.4286 6 no
GO:0043069 negative regulation of programmed cell death 21.4286 5 no
GO:0043085 positive regulation of catalytic activity 21.4286 4 no
GO:0043254 regulation of protein-containing complex assembly 21.4286 5 no
GO:0043412 macromolecule modification 21.4286 4 no
GO:0044087 regulation of cellular component biogenesis 21.4286 4 no
GO:0048584 positive regulation of response to stimulus 21.4286 4 no
GO:0048585 negative regulation of response to stimulus 21.4286 4 no
GO:0051248 negative regulation of protein metabolic process 21.4286 6 no
GO:0071702 organic substance transport 21.4286 4 no
GO:0071705 nitrogen compound transport 21.4286 4 no
GO:0021762 substantia nigra development 21.4286 4 no
GO:0032880 regulation of protein localization 21.4286 5 no
GO:0033043 regulation of organelle organization 21.4286 5 no
GO:0051493 regulation of cytoskeleton organization 21.4286 6 no
GO:0060341 regulation of cellular localization 21.4286 4 no
GO:0071310 cellular response to organic substance 21.4286 4 no
GO:0051726 regulation of cell cycle 21.4286 4 no
GO:0022603 regulation of anatomical structure morphogenesis 17.8571 4 yes
GO:0034329 cell junction assembly 14.2857 5 yes
GO:0030855 epithelial cell differentiation 10.7143 4 yes
GO:0030859 polarized epithelial cell differentiation 10.7143 5 yes
GO:0035088 establishment or maintenance of apical/basal cell polarity 10.7143 4 yes
GO:0035089 establishment of apical/basal cell polarity 10.7143 5 yes
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 10.7143 5 yes
GO:0045198 establishment of epithelial cell apical/basal polarity 10.7143 5 yes
GO:0051056 regulation of small GTPase mediated signal transduction 10.7143 6 yes
GO:0061162 establishment of monopolar cell polarity 10.7143 4 yes
GO:0090162 establishment of epithelial cell polarity 10.7143 4 yes
GO:0007600 sensory perception 7.1429 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
2ABB_HUMAN [view interactions] High throughput no yes
TRPM7_HUMAN [view interactions] High throughput no no
NAA10_HUMAN [view interactions] High throughput no yes
ATP5H_HUMAN [view interactions] High throughput no yes
NUP98_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no
UN45A_HUMAN [view interactions] High throughput no yes
IMDH2_HUMAN [view interactions] High throughput no yes
KTN1_HUMAN [view entry] [view interactions] High throughput yes yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
DYR1A_HUMAN [view interactions] High throughput no yes
MYZAP_HUMAN [view interactions] High throughput no yes
GRL1A_HUMAN [view interactions] High throughput no no
MTR1A_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
IKBB_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
PCM1_HUMAN [view interactions] High throughput no yes
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
JADE2_HUMAN [view interactions] High throughput no yes
SKAP1_HUMAN [view interactions] High throughput no no
MCM2_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
DQX1_HUMAN [view interactions] High throughput no no
CDC16_HUMAN [view interactions] High throughput no yes
LZTS2_HUMAN [view interactions] High throughput no no
TMOD4_HUMAN [view interactions] High throughput no no
CNDH2_HUMAN [view interactions] High throughput no no
KAD9_HUMAN [view interactions] High throughput no yes
BPNT1_HUMAN [view interactions] High throughput no yes
CRYL1_HUMAN [view interactions] High throughput no yes
P4HA2_HUMAN [view interactions] High throughput no no
DNAI7_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
APEX1_HUMAN [view interactions] High throughput no yes
BRD7_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
RTRAF_HUMAN [view interactions] High throughput no yes
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
FUBP3_HUMAN [view interactions] High throughput no yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
CH10_HUMAN [view interactions] High throughput no yes
RT17_HUMAN [view interactions] High throughput no yes
MYL6B_HUMAN [view entry] [view interactions] High throughput yes no
NHP2_HUMAN [view interactions] High throughput no yes
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
RUXE_HUMAN [view interactions] High throughput no no
CHM4C_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
TRI52_HUMAN [view interactions] High throughput no yes
TTYH1_HUMAN [view entry] [view interactions] High throughput yes no
NEK10_HUMAN [view interactions] High throughput no no
DKK3_HUMAN [view interactions] High throughput no yes
CAN2_HUMAN [view entry] [view interactions] High throughput yes no
ACRBP_HUMAN [view interactions] High throughput no no
PNMA2_HUMAN [view interactions] High throughput no yes
KRT38_HUMAN [view interactions] High throughput no no
K22E_HUMAN [view interactions] High throughput no no
MR1L1_HUMAN [view interactions] High throughput no no
TBC15_HUMAN [view interactions] High throughput no yes
LURA1_HUMAN [view interactions] High throughput no yes
COPT1_HUMAN [view interactions] High throughput no no
ABTB2_HUMAN [view interactions] High throughput no yes
GALD1_HUMAN [view interactions] High throughput no yes
KCNA2_HUMAN [view entry] [view interactions] High throughput yes yes
GSDMC_HUMAN [view interactions] High throughput no no
LRAD1_HUMAN [view interactions] High throughput no no
K1C40_HUMAN [view interactions] High throughput no no
CREB3_HUMAN [view interactions] High throughput no no
UBXN6_HUMAN [view entry] [view interactions] High throughput yes yes
SAMD3_HUMAN [view interactions] High throughput no no
RGF1A_HUMAN [view interactions] High throughput no yes
ZNRD2_HUMAN [view interactions] High throughput no yes
SF3B3_HUMAN [view interactions] High throughput no yes
MAGA9_HUMAN [view interactions] High throughput no no
NGN3_HUMAN [view interactions] High throughput no no
KCNA3_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOV_HUMAN [view interactions] High throughput no no
SOX2_HUMAN [view interactions] High throughput no yes
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
CCNF_HUMAN [view interactions] High throughput no no
CFAH_HUMAN [view interactions] High throughput no no
IER5_HUMAN [view interactions] High throughput no yes
SETD2_HUMAN [view interactions] High throughput no yes
CE152_HUMAN [view interactions] High throughput no yes
PROF1_HUMAN [view entry] [view interactions] High throughput yes yes
GSK3A_HUMAN [view interactions] High throughput no yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
COP1_HUMAN [view interactions] High throughput no no