Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MYL6_HUMAN

GO
G2C
SynGO

Regulatory light chain of myosin. Does not bind calcium. [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in MYL6_HUMAN
GO:0019900 kinase binding 31.6456 4 no
GO:0017076 purine nucleotide binding 30.3797 4 no
GO:0032555 purine ribonucleotide binding 30.3797 4 no
GO:0035639 purine ribonucleoside triphosphate binding 29.1139 4 no
GO:0046872 metal ion binding 27.8481 4 yes
GO:0019901 protein kinase binding 27.8481 5 no
GO:0003779 actin binding 22.7848 4 no
GO:0030554 adenyl nucleotide binding 22.7848 5 no
GO:0032559 adenyl ribonucleotide binding 22.7848 5 no
GO:0005524 ATP binding 21.5190 5 no
GO:0005509 calcium ion binding 10.1266 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MYL6_HUMAN
GO:0048522 positive regulation of cellular process 62.0253 4 no
GO:0060255 regulation of macromolecule metabolic process 60.7595 4 no
GO:0080090 regulation of primary metabolic process 54.4304 4 no
GO:0031323 regulation of cellular metabolic process 53.1646 4 no
GO:0048523 negative regulation of cellular process 51.8987 4 no
GO:0051171 regulation of nitrogen compound metabolic process 51.8987 4 no
GO:0009893 positive regulation of metabolic process 50.6329 4 no
GO:0010604 positive regulation of macromolecule metabolic process 49.3671 5 no
GO:0006996 organelle organization 48.1013 4 no
GO:0010646 regulation of cell communication 46.8354 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 45.5696 5 no
GO:0051128 regulation of cellular component organization 43.0380 4 no
GO:0009966 regulation of signal transduction 43.0380 4 no
GO:0008104 protein localization 40.5063 4 no
GO:0051049 regulation of transport 40.5063 4 no
GO:0010468 regulation of gene expression 40.5063 5 no
GO:0031325 positive regulation of cellular metabolic process 40.5063 5 no
GO:0051246 regulation of protein metabolic process 40.5063 5 no
GO:0031399 regulation of protein modification process 36.7089 6 no
GO:0051247 positive regulation of protein metabolic process 35.4430 6 no
GO:0009892 negative regulation of metabolic process 31.6456 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 31.6456 5 no
GO:0043412 macromolecule modification 31.6456 4 no
GO:0019220 regulation of phosphate metabolic process 31.6456 6 no
GO:0051174 regulation of phosphorus metabolic process 31.6456 5 no
GO:0022607 cellular component assembly 31.6456 4 no
GO:0007010 cytoskeleton organization 31.6456 5 no
GO:0036211 protein modification process 30.3797 4 no
GO:1902531 regulation of intracellular signal transduction 30.3797 5 no
GO:0009889 regulation of biosynthetic process 29.1139 4 no
GO:0031326 regulation of cellular biosynthetic process 29.1139 5 no
GO:0031401 positive regulation of protein modification process 29.1139 7 no
GO:0042325 regulation of phosphorylation 29.1139 7 no
GO:0060341 regulation of cellular localization 27.8481 4 no
GO:0010556 regulation of macromolecule biosynthetic process 27.8481 5 no
GO:0010605 negative regulation of macromolecule metabolic process 27.8481 5 no
GO:0031324 negative regulation of cellular metabolic process 27.8481 5 no
GO:0048584 positive regulation of response to stimulus 27.8481 4 no
GO:0033043 regulation of organelle organization 27.8481 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 26.5823 5 no
GO:0051252 regulation of RNA metabolic process 26.5823 5 no
GO:0030030 cell projection organization 26.5823 4 no
GO:0010562 positive regulation of phosphorus metabolic process 26.5823 6 no
GO:0045937 positive regulation of phosphate metabolic process 26.5823 7 no
GO:0010647 positive regulation of cell communication 26.5823 5 no
GO:0023056 positive regulation of signaling 26.5823 4 no
GO:0032880 regulation of protein localization 25.3165 5 no
GO:0010941 regulation of cell death 25.3165 4 no
GO:0045595 regulation of cell differentiation 25.3165 4 no
GO:0001932 regulation of protein phosphorylation 25.3165 7 no
GO:0051050 positive regulation of transport 25.3165 4 no
GO:0009967 positive regulation of signal transduction 25.3165 5 no
GO:0042981 regulation of apoptotic process 24.0506 6 no
GO:0043067 regulation of programmed cell death 24.0506 5 no
GO:0042327 positive regulation of phosphorylation 24.0506 8 no
GO:0043085 positive regulation of catalytic activity 24.0506 4 no
GO:0051726 regulation of cell cycle 24.0506 4 no
GO:0071310 cellular response to organic substance 24.0506 4 no
GO:0051493 regulation of cytoskeleton organization 24.0506 6 no
GO:0051248 negative regulation of protein metabolic process 22.7848 6 no
GO:0022603 regulation of anatomical structure morphogenesis 22.7848 4 no
GO:0032970 regulation of actin filament-based process 22.7848 4 no
GO:0044087 regulation of cellular component biogenesis 22.7848 4 no
GO:0016192 vesicle-mediated transport 21.5190 4 no
GO:0006355 regulation of DNA-templated transcription 21.5190 6 no
GO:0042127 regulation of cell population proliferation 21.5190 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 21.5190 6 no
GO:0051094 positive regulation of developmental process 21.5190 4 no
GO:1903506 regulation of nucleic acid-templated transcription 21.5190 7 no
GO:2001141 regulation of RNA biosynthetic process 21.5190 6 no
GO:0097435 supramolecular fiber organization 21.5190 4 no
GO:0120036 plasma membrane bounded cell projection organization 21.5190 5 no
GO:0001934 positive regulation of protein phosphorylation 21.5190 8 no
GO:0051336 regulation of hydrolase activity 21.5190 4 no
GO:0051130 positive regulation of cellular component organization 21.5190 5 no
GO:0071702 organic substance transport 20.2532 4 no
GO:0010648 negative regulation of cell communication 20.2532 5 no
GO:0023057 negative regulation of signaling 20.2532 4 no
GO:0031400 negative regulation of protein modification process 20.2532 7 no
GO:0051338 regulation of transferase activity 20.2532 4 no
GO:0010243 response to organonitrogen compound 20.2532 4 no
GO:0032956 regulation of actin cytoskeleton organization 20.2532 5 no
GO:0006936 muscle contraction 11.3924 4 yes
GO:0060537 muscle tissue development 7.5949 4 yes
GO:0007519 skeletal muscle tissue development 5.0633 5 yes
GO:0070252 actin-mediated cell contraction 5.0633 4 yes
GO:0030049 muscle filament sliding 3.7975 6 yes
GO:0033275 actin-myosin filament sliding 3.7975 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in MYL6_HUMAN
DOID:0050700 cardiomyopathy 3.7975 4 no
DOID:0060036 intrinsic cardiomyopathy 3.7975 5 no
DOID:114 heart disease 3.7975 3 no
DOID:0050155 sensory system disease 3.7975 3 no
DOID:0050563 nonsyndromic deafness 3.7975 5 no
DOID:0050564 autosomal dominant nonsyndromic deafness 3.7975 6 no
DOID:2742 auditory system disease 3.7975 4 no
DOID:2843 long QT syndrome 2.5316 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ESR1_HUMAN [view interactions] Low throughput no no
PP1B_HUMAN [view entry] [view interactions] Low throughput yes yes
TRI59_HUMAN [view interactions] Low throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
WWP2_HUMAN [view interactions] High throughput no no
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
FBXW8_HUMAN [view interactions] High throughput no yes
CUL9_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
EMC5_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
LRC31_HUMAN [view interactions] High throughput no no
DUX4_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
AURKB_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
SMCA2_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
BRD4_HUMAN [view interactions] High throughput no yes
NINL_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
F16P1_HUMAN [view interactions] High throughput no no
ML12B_HUMAN [view interactions] High throughput no no
INSI1_HUMAN [view interactions] High throughput no no
ANDR_HUMAN [view interactions] High throughput no no
ISG15_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
TPPP2_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
TPPC8_HUMAN [view interactions] High throughput no yes
SRBD1_HUMAN [view interactions] High throughput no yes
PARD3_HUMAN [view interactions] High throughput no yes
IQGA2_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
UBR5_HUMAN [view interactions] High throughput no no
FGD5_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
SIK2_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
ML12A_HUMAN [view interactions] High throughput no no
MYL9_HUMAN [view interactions] High throughput no no
MYO9B_HUMAN [view interactions] High throughput no yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
DESM_HUMAN [view entry] [view interactions] High throughput yes no
ATPB_HUMAN [view interactions] High throughput no yes
GRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
SAHH2_HUMAN [view entry] [view interactions] High throughput yes yes
AHNK_HUMAN [view entry] [view interactions] High throughput yes yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
SERA_HUMAN [view entry] [view interactions] High throughput yes yes
RCN1_HUMAN [view interactions] High throughput no yes
ORN_HUMAN [view interactions] High throughput no no
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
STMN1_HUMAN [view interactions] High throughput no yes
TPM2_HUMAN [view entry] [view interactions] High throughput yes yes
VINC_HUMAN [view entry] [view interactions] High throughput yes no
HOOK3_HUMAN [view entry] [view interactions] High throughput yes yes
HOOK1_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
ACBD5_HUMAN [view entry] [view interactions] High throughput yes yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
NAA40_HUMAN [view interactions] High throughput no no
DPP4_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
OPTN_HUMAN [view interactions] High throughput no yes
SLN11_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
MLH1_HUMAN [view interactions] High throughput no yes
HMGB2_HUMAN [view interactions] High throughput no yes
ARRB1_HUMAN [view entry] [view interactions] High throughput yes yes
ARRB2_HUMAN [view entry] [view interactions] High throughput yes no
2ABB_HUMAN [view interactions] High throughput no yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
UBP18_HUMAN [view interactions] High throughput no yes
UBP45_HUMAN [view interactions] High throughput no yes
BECN1_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
ATF2_HUMAN [view interactions] High throughput no yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
ANLN_HUMAN [view interactions] High throughput no yes
CALL3_HUMAN [view interactions] High throughput no yes
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
AAPK1_HUMAN [view interactions] High throughput no no
AAKB1_HUMAN [view interactions] High throughput no yes
OCRL_HUMAN [view interactions] High throughput no yes
MET14_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
EIF1B_HUMAN [view interactions] High throughput no no
IF6_HUMAN [view interactions] High throughput no yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
PINX1_HUMAN [view interactions] High throughput no yes
IKKE_HUMAN [view interactions] High throughput no yes
HLAB_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
LITD1_HUMAN [view interactions] High throughput no no
TCTP_HUMAN [view entry] [view interactions] High throughput yes yes
CD177_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
CNDD3_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
ATS12_HUMAN [view interactions] High throughput no no
GA2L3_HUMAN [view interactions] High throughput no no
DDT4L_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
CPSF5_HUMAN [view interactions] High throughput no yes
DNJB9_HUMAN [view interactions] High throughput no yes
PHOCN_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
IKKA_HUMAN [view interactions] High throughput no yes
NEMO_HUMAN [view interactions] High throughput no yes
M3K3_HUMAN [view interactions] High throughput no no
RIPK3_HUMAN [view interactions] High throughput no no
TNR1A_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
SETD7_HUMAN [view interactions] High throughput no yes
TIF1A_HUMAN [view interactions] High throughput no yes
TSYL6_HUMAN [view interactions] High throughput no no
FHI1B_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
RBTN2_HUMAN [view interactions] High throughput no yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
UBP46_HUMAN [view entry] [view interactions] High throughput yes yes
SRRM2_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
TSG10_HUMAN [view interactions] High throughput no no
ITA4_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
FBX32_HUMAN [view interactions] High throughput no no
PAN2_HUMAN [view interactions] High throughput no no
GLP1R_HUMAN [view interactions] High throughput no no
SUZ12_HUMAN [view interactions] High throughput no no
EED_HUMAN [view interactions] High throughput no yes
LEG3_HUMAN [view interactions] High throughput no yes
MYH11_HUMAN [view entry] [view interactions] High throughput yes no
CBX4_HUMAN [view interactions] High throughput no yes
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
MYO19_HUMAN [view interactions] High throughput no yes
BD1L1_HUMAN [view interactions] High throughput no yes
MY18A_HUMAN [view entry] [view interactions] High throughput yes yes
MYO1C_HUMAN [view entry] [view interactions] High throughput yes yes
SHCBP_HUMAN [view interactions] High throughput no no
VPS28_HUMAN [view entry] [view interactions] High throughput yes yes
KBP_HUMAN [view interactions] High throughput no yes
MYH10_HUMAN [view entry] [view interactions] High throughput yes yes
MCM2_HUMAN [view interactions] High throughput no no
KSR1_HUMAN [view interactions] High throughput no yes
CEBPA_HUMAN [view interactions] High throughput no yes
F210A_HUMAN [view interactions] High throughput no yes
MYH14_HUMAN [view entry] [view interactions] High throughput yes no
NEB1_HUMAN [view entry] [view interactions] High throughput yes yes
LIMA1_HUMAN [view entry] [view interactions] High throughput yes no
IQGA3_HUMAN [view interactions] High throughput no no
RANG_HUMAN [view interactions] High throughput no no
MYL6B_HUMAN [view entry] [view interactions] High throughput yes no
FACD2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
DC4L2_HUMAN [view interactions] High throughput no no
HDAC6_HUMAN [view interactions] High throughput no yes
DX39B_HUMAN [view interactions] High throughput no no
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
ARNT_HUMAN [view entry] [view interactions] High throughput yes yes
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
TBX3_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
PTC1_HUMAN [view entry] [view interactions] High throughput yes yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
MEP50_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
CHD3_HUMAN [view interactions] High throughput no yes
CHD4_HUMAN [view interactions] High throughput no yes
TNFA_HUMAN [view interactions] High throughput no no
HEXI1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
REQU_HUMAN [view interactions] High throughput no yes
PPT1_HUMAN [view interactions] High throughput no yes
RN181_HUMAN [view interactions] High throughput no no
SENP2_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
TISD_HUMAN [view interactions] High throughput no no
CDK9_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
ACTC_HUMAN [view interactions] High throughput no no
RBX1_HUMAN [view entry] [view interactions] High throughput yes no
TET2_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
CTCF_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
RU17_HUMAN [view interactions] High throughput no yes
MYH15_HUMAN [view interactions] Computational no yes
MYO6_HUMAN [view entry] [view interactions] Computational yes no
RHOC_HUMAN [view interactions] Computational no no
MLRA_HUMAN [view interactions] Computational no no
RHOA_HUMAN [view entry] [view interactions] Computational yes yes
TPM1_HUMAN [view entry] [view interactions] Computational yes no
MYLK_HUMAN [view interactions] Computational no no
PAK2_HUMAN [view entry] [view interactions] Computational yes no
PAK1_HUMAN [view entry] [view interactions] Computational yes yes
MYL5_HUMAN [view interactions] Computational no no
MYPT1_HUMAN [view entry] [view interactions] Computational yes yes
MYH13_HUMAN [view interactions] Computational no no
MYH8_HUMAN [view interactions] Computational no no
ACTG_HUMAN [view entry] [view interactions] Computational yes yes
MYLK3_HUMAN [view interactions] Computational no no
MLRV_HUMAN [view interactions] Computational no no
MYL1_HUMAN [view interactions] Computational no no
ROCK1_HUMAN [view entry] [view interactions] Computational yes yes
ROCK2_HUMAN [view entry] [view interactions] Computational yes yes
MLRS_HUMAN [view interactions] Computational no no
MYL10_HUMAN [view interactions] Computational no no
MYPT2_HUMAN [view interactions] Computational no no