VPS28_HUMAN
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in VPS28_HUMAN |
---|---|---|---|---|
GO:0043130 | ubiquitin binding | 7.3171 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in VPS28_HUMAN |
---|---|---|---|---|
GO:0031323 | regulation of cellular metabolic process | 56.0976 | 4 | no |
GO:0006996 | organelle organization | 56.0976 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 51.2195 | 4 | yes |
GO:0008104 | protein localization | 51.2195 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 46.3415 | 4 | yes |
GO:0071702 | organic substance transport | 46.3415 | 4 | yes |
GO:0071705 | nitrogen compound transport | 43.9024 | 4 | yes |
GO:0022607 | cellular component assembly | 43.9024 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 41.4634 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 41.4634 | 4 | yes |
GO:0015031 | protein transport | 41.4634 | 4 | yes |
GO:0016192 | vesicle-mediated transport | 41.4634 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 39.0244 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 39.0244 | 4 | no |
GO:0051049 | regulation of transport | 36.5854 | 4 | yes |
GO:0044087 | regulation of cellular component biogenesis | 36.5854 | 4 | no |
GO:0070925 | organelle assembly | 31.7073 | 5 | yes |
GO:0010646 | regulation of cell communication | 29.2683 | 4 | no |
GO:0033043 | regulation of organelle organization | 29.2683 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 29.2683 | 4 | yes |
GO:0009894 | regulation of catabolic process | 29.2683 | 4 | yes |
GO:0051050 | positive regulation of transport | 26.8293 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 26.8293 | 5 | yes |
GO:0009966 | regulation of signal transduction | 26.8293 | 4 | no |
GO:0044089 | positive regulation of cellular component biogenesis | 26.8293 | 5 | no |
GO:0061024 | membrane organization | 26.8293 | 4 | no |
GO:0007034 | vacuolar transport | 26.8293 | 4 | yes |
GO:0016050 | vesicle organization | 26.8293 | 5 | yes |
GO:0051130 | positive regulation of cellular component organization | 24.3902 | 5 | yes |
GO:0043933 | protein-containing complex organization | 24.3902 | 4 | no |
GO:0051726 | regulation of cell cycle | 24.3902 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 24.3902 | 4 | no |
GO:0010468 | regulation of gene expression | 24.3902 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 24.3902 | 5 | no |
GO:0031329 | regulation of cellular catabolic process | 24.3902 | 5 | no |
GO:0007032 | endosome organization | 24.3902 | 6 | yes |
GO:0009892 | negative regulation of metabolic process | 24.3902 | 4 | yes |
GO:0007010 | cytoskeleton organization | 21.9512 | 5 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 21.9512 | 5 | no |
GO:0010506 | regulation of autophagy | 21.9512 | 6 | no |
GO:0022411 | cellular component disassembly | 21.9512 | 4 | no |
GO:0006886 | intracellular protein transport | 21.9512 | 4 | yes |
GO:0009057 | macromolecule catabolic process | 21.9512 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 21.9512 | 5 | yes |
GO:0016197 | endosomal transport | 21.9512 | 4 | yes |
GO:0036257 | multivesicular body organization | 21.9512 | 7 | yes |
GO:0036258 | multivesicular body assembly | 21.9512 | 6 | yes |
GO:0051603 | proteolysis involved in protein catabolic process | 19.5122 | 5 | yes |
GO:0060341 | regulation of cellular localization | 19.5122 | 4 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 19.5122 | 4 | yes |
GO:0006508 | proteolysis | 19.5122 | 4 | yes |
GO:0031399 | regulation of protein modification process | 19.5122 | 6 | yes |
GO:0032880 | regulation of protein localization | 19.5122 | 5 | yes |
GO:0043632 | modification-dependent macromolecule catabolic process | 17.0732 | 5 | yes |
GO:0044265 | cellular macromolecule catabolic process | 17.0732 | 4 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 17.0732 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 17.0732 | 5 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 17.0732 | 5 | yes |
GO:0016236 | macroautophagy | 17.0732 | 4 | yes |
GO:0019941 | modification-dependent protein catabolic process | 17.0732 | 6 | yes |
GO:0051223 | regulation of protein transport | 14.6341 | 5 | yes |
GO:0051247 | positive regulation of protein metabolic process | 14.6341 | 6 | yes |
GO:0070201 | regulation of establishment of protein localization | 14.6341 | 6 | yes |
GO:0006511 | ubiquitin-dependent protein catabolic process | 14.6341 | 7 | yes |
GO:0033365 | protein localization to organelle | 14.6341 | 5 | yes |
GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | 14.6341 | 8 | yes |
GO:0045324 | late endosome to vacuole transport | 12.1951 | 5 | yes |
GO:0071985 | multivesicular body sorting pathway | 12.1951 | 5 | yes |
GO:0072594 | establishment of protein localization to organelle | 12.1951 | 4 | yes |
GO:0032509 | endosome transport via multivesicular body sorting pathway | 12.1951 | 5 | yes |
GO:0051248 | negative regulation of protein metabolic process | 9.7561 | 6 | yes |
GO:0072665 | protein localization to vacuole | 9.7561 | 6 | yes |
GO:0072666 | establishment of protein localization to vacuole | 9.7561 | 5 | yes |
GO:1903829 | positive regulation of protein localization | 9.7561 | 5 | yes |
GO:0030100 | regulation of endocytosis | 9.7561 | 5 | yes |
GO:0042176 | regulation of protein catabolic process | 9.7561 | 5 | yes |
GO:0045807 | positive regulation of endocytosis | 7.3171 | 5 | yes |
GO:0009896 | positive regulation of catabolic process | 7.3171 | 5 | yes |
GO:0031400 | negative regulation of protein modification process | 7.3171 | 7 | yes |
GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway | 7.3171 | 6 | yes |
GO:0051222 | positive regulation of protein transport | 4.8780 | 5 | yes |
GO:1903320 | regulation of protein modification by small protein conjugation or removal | 4.8780 | 7 | yes |
GO:1903321 | negative regulation of protein modification by small protein conjugation or removal | 4.8780 | 8 | yes |
GO:1904951 | positive regulation of establishment of protein localization | 4.8780 | 6 | yes |
GO:2000395 | regulation of ubiquitin-dependent endocytosis | 4.8780 | 6 | yes |
GO:2000397 | positive regulation of ubiquitin-dependent endocytosis | 4.8780 | 6 | yes |
GO:0031396 | regulation of protein ubiquitination | 4.8780 | 8 | yes |
GO:0031397 | negative regulation of protein ubiquitination | 4.8780 | 9 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
VP37B_HUMAN | [view interactions] | Low throughput | no | yes |
M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
TS101_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MB12A_HUMAN | [view interactions] | Low throughput | no | yes |
VP37A_HUMAN | [view interactions] | Low throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DFFB_HUMAN | [view interactions] | Low throughput | no | yes |
DFFA_HUMAN | [view interactions] | Low throughput | no | yes |
AKTIP_HUMAN | [view interactions] | Low throughput | no | yes |
BCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SNF8_HUMAN | [view interactions] | Low throughput | no | yes |
VPS25_HUMAN | [view interactions] | Low throughput | no | yes |
VPS36_HUMAN | [view interactions] | Low throughput | no | yes |
ALG2_HUMAN | [view interactions] | Low throughput | no | yes |
UBAP1_HUMAN | [view interactions] | Low throughput | no | yes |
VP37C_HUMAN | [view interactions] | Low throughput | no | yes |
NIF3L_HUMAN | [view interactions] | High throughput | no | yes |
DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HIP1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI14_HUMAN | [view interactions] | High throughput | no | yes |
SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SKIL_HUMAN | [view interactions] | High throughput | no | yes |
VPS52_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SMN_HUMAN | [view interactions] | High throughput | no | yes |
CE57L_HUMAN | [view interactions] | High throughput | no | yes |
CEP55_HUMAN | [view interactions] | High throughput | no | yes |
CD2AP_HUMAN | [view interactions] | High throughput | no | no |
PAR6B_HUMAN | [view interactions] | High throughput | no | no |
SGO2_HUMAN | [view interactions] | High throughput | no | no |
OBSCN_HUMAN | [view interactions] | High throughput | no | yes |
TAF10_HUMAN | [view interactions] | High throughput | no | yes |
VATG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBP_HUMAN | [view interactions] | High throughput | no | yes |
VPP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MUC13_HUMAN | [view interactions] | High throughput | no | no |
RM03_HUMAN | [view interactions] | High throughput | no | yes |
VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S35F6_HUMAN | [view interactions] | High throughput | no | yes |
CLCN7_HUMAN | [view interactions] | High throughput | no | yes |
CHM2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DHX36_HUMAN | [view interactions] | High throughput | no | yes |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CB069_HUMAN | [view interactions] | High throughput | no | yes |
S23IP_HUMAN | [view interactions] | High throughput | no | yes |
KATIP_HUMAN | [view interactions] | High throughput | no | yes |
UMAD1_HUMAN | [view interactions] | High throughput | no | yes |
PGBM_HUMAN | [view interactions] | High throughput | no | no |
HBE_HUMAN | [view interactions] | High throughput | no | no |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S2541_HUMAN | [view interactions] | High throughput | no | no |
SCN2B_HUMAN | [view interactions] | High throughput | no | no |
ARRD1_HUMAN | [view interactions] | High throughput | no | yes |
VP37D_HUMAN | [view interactions] | High throughput | no | no |
AKA11_HUMAN | [view interactions] | High throughput | no | yes |
MB12B_HUMAN | [view interactions] | High throughput | no | no |
RGPD5_HUMAN | [view interactions] | High throughput | no | no |
PCP2_HUMAN | [view interactions] | High throughput | no | no |
STXB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COQ3_HUMAN | [view interactions] | High throughput | no | no |
EVG1_HUMAN | [view interactions] | High throughput | no | no |
PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FINC_HUMAN | [view interactions] | High throughput | no | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
USBP1_HUMAN | [view interactions] | High throughput | no | no |
TRI27_HUMAN | [view interactions] | High throughput | no | yes |
GO45_HUMAN | [view interactions] | High throughput | no | yes |
GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SAXO1_HUMAN | [view interactions] | High throughput | no | no |
ASF1A_HUMAN | [view interactions] | High throughput | no | no |
FABPH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GBRAP_HUMAN | [view interactions] | High throughput | no | no |
PCNA_HUMAN | [view interactions] | High throughput | no | no |
ITF2_HUMAN | [view interactions] | High throughput | no | yes |
HTF4_HUMAN | [view interactions] | High throughput | no | yes |
CBX5_HUMAN | [view interactions] | High throughput | no | yes |
MBIP1_HUMAN | [view interactions] | High throughput | no | yes |
TRI54_HUMAN | [view interactions] | High throughput | no | no |
CARD9_HUMAN | [view interactions] | High throughput | no | no |
RASF5_HUMAN | [view interactions] | High throughput | no | yes |
PNMA5_HUMAN | [view interactions] | High throughput | no | yes |
INCA1_HUMAN | [view interactions] | High throughput | no | no |
UBP2_HUMAN | [view interactions] | High throughput | no | yes |
LMO3_HUMAN | [view interactions] | High throughput | no | no |
TSNAX_HUMAN | [view interactions] | High throughput | no | yes |
CDK18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NRDE2_HUMAN | [view interactions] | High throughput | no | yes |
AAKB2_HUMAN | [view interactions] | High throughput | no | yes |
BEX2_HUMAN | [view interactions] | High throughput | no | yes |
CC146_HUMAN | [view interactions] | High throughput | no | yes |
COX5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SUOX_HUMAN | [view interactions] | High throughput | no | no |
SHC3_HUMAN | [view interactions] | High throughput | no | yes |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
GEM_HUMAN | [view interactions] | High throughput | no | yes |
UBE2U_HUMAN | [view interactions] | High throughput | no | no |
AB17A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BRCA2_HUMAN | [view interactions] | High throughput | no | no |
DCAF6_HUMAN | [view interactions] | High throughput | no | no |
MD1L1_HUMAN | [view interactions] | High throughput | no | yes |
HAUS8_HUMAN | [view interactions] | High throughput | no | yes |
MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TAF1_HUMAN | [view interactions] | High throughput | no | yes |
BAZ2A_HUMAN | [view interactions] | High throughput | no | no |
CUTA_HUMAN | [view interactions] | High throughput | no | yes |
E41LB_HUMAN | [view interactions] | High throughput | no | yes |
RBM26_HUMAN | [view interactions] | High throughput | no | yes |
SETX_HUMAN | [view interactions] | High throughput | no | yes |
KNL1_HUMAN | [view interactions] | High throughput | no | no |
TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
CGAS_HUMAN | [view interactions] | High throughput | no | yes |
APEX1_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
IL1B_HUMAN | [view interactions] | High throughput | no | no |
UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
CP2J2_HUMAN | [view interactions] | High throughput | no | no |
ACY1_HUMAN | [view interactions] | High throughput | no | no |
F227B_HUMAN | [view interactions] | High throughput | no | yes |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
PRP6_HUMAN | [view interactions] | High throughput | no | yes |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
ZDH23_HUMAN | [view interactions] | High throughput | no | no |
CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
PEBB_HUMAN | [view interactions] | High throughput | no | no |
SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
S1PR1_HUMAN | [view interactions] | High throughput | no | no |
PDE2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBE3B_HUMAN | [view interactions] | High throughput | no | yes |
WDFY1_HUMAN | [view interactions] | High throughput | no | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RIT1_HUMAN | [view interactions] | High throughput | no | yes |
HSP7C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VTA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
HGS_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
HDAC6_HUMAN | [view interactions] | Computational | no | yes |
VPS4B_HUMAN | [view interactions] | Computational | no | yes |
CFTR_HUMAN | [view interactions] | Computational | no | no |
PCNT_HUMAN | [view interactions] | Computational | no | yes |
PARK7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CHM4C_HUMAN | [view interactions] | Computational | no | yes |
CHM1B_HUMAN | [view interactions] | Computational | no | yes |
IST1_HUMAN | [view interactions] | Computational | no | yes |
STAM2_HUMAN | [view interactions] | Computational | no | yes |
RNAS1_HUMAN | [view interactions] | Computational | no | yes |
VPS4A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PLIN3_HUMAN | [view interactions] | Computational | no | yes |
STAM1_HUMAN | [view interactions] | Computational | no | yes |
CHMP5_HUMAN | [view interactions] | Computational | no | yes |
PLIN2_HUMAN | [view interactions] | Computational | no | no |
CHMP6_HUMAN | [view interactions] | Computational | no | yes |
AR13B_HUMAN | [view interactions] | Computational | no | yes |
HBB_HUMAN | [view interactions] | Computational | no | no |
CHM1A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CHM4B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CHM2A_HUMAN | [view interactions] | Computational | no | yes |
PDC6I_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CETN1_HUMAN | [view interactions] | Computational | no | no |
CHMP7_HUMAN | [view interactions] | Computational | no | yes |
IFT88_HUMAN | [view interactions] | Computational | no | no |
CHM4A_HUMAN | [view interactions] | Computational | no | no |