PDE2A_HUMAN
Evidence for PS localization
Functions
Regulates mitochondrial cAMP levels and respiration . Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002310 | MOD_NMyristoyl | MOD | 1 | 7 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PDE2A_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 35.1351 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 24.3243 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 24.3243 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 21.6216 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 21.6216 | 5 | yes |
| GO:0042803 | protein homodimerization activity | 21.6216 | 4 | yes |
| GO:0046914 | transition metal ion binding | 13.5135 | 5 | yes |
| GO:0008270 | zinc ion binding | 10.8108 | 6 | yes |
| GO:0019001 | guanyl nucleotide binding | 10.8108 | 5 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 10.8108 | 5 | yes |
| GO:0000287 | magnesium ion binding | 5.4054 | 5 | yes |
| GO:0004112 | cyclic-nucleotide phosphodiesterase activity | 5.4054 | 6 | yes |
| GO:0004114 | 3,5-cyclic-nucleotide phosphodiesterase activity | 5.4054 | 7 | yes |
| GO:0004115 | 3,5-cyclic-AMP phosphodiesterase activity | 5.4054 | 8 | yes |
| GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | 5.4054 | 8 | yes |
| GO:0008081 | phosphoric diester hydrolase activity | 5.4054 | 5 | yes |
| GO:0030551 | cyclic nucleotide binding | 5.4054 | 4 | yes |
| GO:0030552 | cAMP binding | 5.4054 | 4 | yes |
| GO:0030553 | cGMP binding | 5.4054 | 4 | yes |
| GO:0030911 | TPR domain binding | 5.4054 | 4 | yes |
| GO:0042301 | phosphate ion binding | 5.4054 | 4 | yes |
| GO:0042578 | phosphoric ester hydrolase activity | 5.4054 | 4 | yes |
| GO:0047555 | 3,5-cyclic-GMP phosphodiesterase activity | 5.4054 | 8 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PDE2A_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 48.6486 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.9459 | 4 | yes |
| GO:0006996 | organelle organization | 45.9459 | 4 | no |
| GO:0009966 | regulation of signal transduction | 40.5405 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 40.5405 | 4 | yes |
| GO:0008104 | protein localization | 40.5405 | 4 | no |
| GO:0071702 | organic substance transport | 40.5405 | 4 | no |
| GO:0071705 | nitrogen compound transport | 37.8378 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 35.1351 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 35.1351 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 35.1351 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 35.1351 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 35.1351 | 4 | yes |
| GO:0051049 | regulation of transport | 35.1351 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 32.4324 | 4 | yes |
| GO:0022607 | cellular component assembly | 32.4324 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 29.7297 | 5 | no |
| GO:0023056 | positive regulation of signaling | 29.7297 | 4 | no |
| GO:0051050 | positive regulation of transport | 29.7297 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 29.7297 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 27.0270 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 27.0270 | 4 | yes |
| GO:0010468 | regulation of gene expression | 27.0270 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.0270 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 27.0270 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 27.0270 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 27.0270 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 27.0270 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 27.0270 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 27.0270 | 5 | yes |
| GO:0015031 | protein transport | 27.0270 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.3243 | 6 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 24.3243 | 4 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 24.3243 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 24.3243 | 6 | yes |
| GO:0009967 | positive regulation of signal transduction | 24.3243 | 5 | no |
| GO:0007005 | mitochondrion organization | 24.3243 | 5 | no |
| GO:0031399 | regulation of protein modification process | 24.3243 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 24.3243 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 21.6216 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.6216 | 5 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.6216 | 5 | yes |
| GO:0080134 | regulation of response to stress | 21.6216 | 4 | yes |
| GO:0061024 | membrane organization | 21.6216 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.6216 | 4 | no |
| GO:0033365 | protein localization to organelle | 21.6216 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 21.6216 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.6216 | 7 | no |
| GO:0019220 | regulation of phosphate metabolic process | 21.6216 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 21.6216 | 7 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 21.6216 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 21.6216 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.6216 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 18.9189 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 18.9189 | 6 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 18.9189 | 5 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 18.9189 | 6 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 18.9189 | 6 | yes |
| GO:0051253 | negative regulation of RNA metabolic process | 18.9189 | 6 | yes |
| GO:0071310 | cellular response to organic substance | 18.9189 | 4 | yes |
| GO:0010648 | negative regulation of cell communication | 16.2162 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 16.2162 | 4 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 16.2162 | 7 | yes |
| GO:1901699 | cellular response to nitrogen compound | 16.2162 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 16.2162 | 4 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 16.2162 | 7 | yes |
| GO:1903507 | negative regulation of nucleic acid-templated transcription | 16.2162 | 8 | yes |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 13.5135 | 8 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 13.5135 | 7 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 13.5135 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 13.5135 | 5 | yes |
| GO:0009968 | negative regulation of signal transduction | 13.5135 | 5 | yes |
| GO:0010243 | response to organonitrogen compound | 13.5135 | 4 | yes |
| GO:0010628 | positive regulation of gene expression | 13.5135 | 6 | yes |
| GO:0048585 | negative regulation of response to stimulus | 13.5135 | 4 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 13.5135 | 4 | yes |
| GO:0006163 | purine nucleotide metabolic process | 10.8108 | 5 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 10.8108 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 10.8108 | 5 | yes |
| GO:0010821 | regulation of mitochondrion organization | 10.8108 | 6 | yes |
| GO:0014070 | response to organic cyclic compound | 10.8108 | 4 | yes |
| GO:0019693 | ribose phosphate metabolic process | 10.8108 | 4 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 10.8108 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 10.8108 | 4 | yes |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 8.1081 | 4 | yes |
| GO:0009187 | cyclic nucleotide metabolic process | 8.1081 | 6 | yes |
| GO:0032101 | regulation of response to external stimulus | 8.1081 | 4 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 8.1081 | 5 | yes |
| GO:0034097 | response to cytokine | 8.1081 | 4 | yes |
| GO:0070848 | response to growth factor | 8.1081 | 4 | yes |
| GO:0071345 | cellular response to cytokine stimulus | 8.1081 | 5 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 8.1081 | 5 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 8.1081 | 4 | yes |
| GO:1902532 | negative regulation of intracellular signal transduction | 8.1081 | 6 | yes |
| GO:0001885 | endothelial cell development | 5.4054 | 5 | yes |
| GO:0002064 | epithelial cell development | 5.4054 | 4 | yes |
| GO:0002521 | leukocyte differentiation | 5.4054 | 4 | yes |
| GO:0002573 | myeloid leukocyte differentiation | 5.4054 | 5 | yes |
| GO:0003018 | vascular process in circulatory system | 5.4054 | 4 | yes |
| GO:0003281 | ventricular septum development | 5.4054 | 4 | yes |
| GO:0006195 | purine nucleotide catabolic process | 5.4054 | 6 | yes |
| GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 5.4054 | 5 | yes |
| GO:0009154 | purine ribonucleotide catabolic process | 5.4054 | 6 | yes |
| GO:0009166 | nucleotide catabolic process | 5.4054 | 6 | yes |
| GO:0009214 | cyclic nucleotide catabolic process | 5.4054 | 7 | yes |
| GO:0009261 | ribonucleotide catabolic process | 5.4054 | 5 | yes |
| GO:0010752 | regulation of cGMP-mediated signaling | 5.4054 | 6 | yes |
| GO:0010754 | negative regulation of cGMP-mediated signaling | 5.4054 | 7 | yes |
| GO:0014074 | response to purine-containing compound | 5.4054 | 5 | yes |
| GO:0019439 | aromatic compound catabolic process | 5.4054 | 4 | yes |
| GO:0019932 | second-messenger-mediated signaling | 5.4054 | 4 | yes |
| GO:0019933 | cAMP-mediated signaling | 5.4054 | 6 | yes |
| GO:0019934 | cGMP-mediated signaling | 5.4054 | 6 | yes |
| GO:0019935 | cyclic-nucleotide-mediated signaling | 5.4054 | 5 | yes |
| GO:0030099 | myeloid cell differentiation | 5.4054 | 4 | yes |
| GO:0030224 | monocyte differentiation | 5.4054 | 6 | yes |
| GO:0031347 | regulation of defense response | 5.4054 | 5 | yes |
| GO:0031349 | positive regulation of defense response | 5.4054 | 5 | yes |
| GO:0034655 | nucleobase-containing compound catabolic process | 5.4054 | 4 | yes |
| GO:0035904 | aorta development | 5.4054 | 5 | yes |
| GO:0036005 | response to macrophage colony-stimulating factor | 5.4054 | 5 | yes |
| GO:0036006 | cellular response to macrophage colony-stimulating factor stimulus | 5.4054 | 6 | yes |
| GO:0043116 | negative regulation of vascular permeability | 5.4054 | 4 | yes |
| GO:0043117 | positive regulation of vascular permeability | 5.4054 | 4 | yes |
| GO:0043949 | regulation of cAMP-mediated signaling | 5.4054 | 6 | yes |
| GO:0043951 | negative regulation of cAMP-mediated signaling | 5.4054 | 7 | yes |
| GO:0044270 | cellular nitrogen compound catabolic process | 5.4054 | 4 | yes |
| GO:0046068 | cGMP metabolic process | 5.4054 | 7 | yes |
| GO:0046069 | cGMP catabolic process | 5.4054 | 7 | yes |
| GO:0046434 | organophosphate catabolic process | 5.4054 | 4 | yes |
| GO:0046683 | response to organophosphorus | 5.4054 | 4 | yes |
| GO:0046700 | heterocycle catabolic process | 5.4054 | 4 | yes |
| GO:0050727 | regulation of inflammatory response | 5.4054 | 5 | yes |
| GO:0050729 | positive regulation of inflammatory response | 5.4054 | 6 | yes |
| GO:0051591 | response to cAMP | 5.4054 | 4 | yes |
| GO:0060840 | artery development | 5.4054 | 4 | yes |
| GO:0061028 | establishment of endothelial barrier | 5.4054 | 6 | yes |
| GO:0070305 | response to cGMP | 5.4054 | 4 | yes |
| GO:0071260 | cellular response to mechanical stimulus | 5.4054 | 4 | yes |
| GO:0071320 | cellular response to cAMP | 5.4054 | 5 | yes |
| GO:0071321 | cellular response to cGMP | 5.4054 | 5 | yes |
| GO:0071466 | cellular response to xenobiotic stimulus | 5.4054 | 4 | yes |
| GO:0071560 | cellular response to transforming growth factor beta stimulus | 5.4054 | 4 | yes |
| GO:0072523 | purine-containing compound catabolic process | 5.4054 | 5 | yes |
| GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus | 5.4054 | 6 | yes |
| GO:0097012 | response to granulocyte macrophage colony-stimulating factor | 5.4054 | 5 | yes |
| GO:1901136 | carbohydrate derivative catabolic process | 5.4054 | 4 | yes |
| GO:1901292 | nucleoside phosphate catabolic process | 5.4054 | 5 | yes |
| GO:1901361 | organic cyclic compound catabolic process | 5.4054 | 4 | yes |
| GO:1903131 | mononuclear cell differentiation | 5.4054 | 5 | yes |
| GO:1904612 | response to 2,3,7,8-tetrachlorodibenzodioxine | 5.4054 | 5 | yes |
| GO:1904613 | cellular response to 2,3,7,8-tetrachlorodibenzodioxine | 5.4054 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| AIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDE2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OBI1_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| SLX4I_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S38A7_HUMAN | [view interactions] | High throughput | no | yes |
| UXS1_HUMAN | [view interactions] | High throughput | no | yes |
| ABCBA_HUMAN | [view interactions] | High throughput | no | yes |
| PLS1_HUMAN | [view interactions] | High throughput | no | no |
| STX16_HUMAN | [view interactions] | High throughput | no | yes |
| A2MG_HUMAN | [view interactions] | High throughput | no | yes |
| CHMP5_HUMAN | [view interactions] | High throughput | no | yes |
| TOM1_HUMAN | [view interactions] | High throughput | no | yes |
| CC127_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAZP2_HUMAN | [view interactions] | High throughput | no | no |
| TAOK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP9B_HUMAN | [view interactions] | High throughput | no | yes |
| RDH13_HUMAN | [view interactions] | High throughput | no | no |
| RELL1_HUMAN | [view interactions] | High throughput | no | yes |
| TMED1_HUMAN | [view interactions] | High throughput | no | yes |
| GL8D1_HUMAN | [view interactions] | High throughput | no | yes |
| HS2ST_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| RN121_HUMAN | [view interactions] | High throughput | no | yes |
| TS101_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP37C_HUMAN | [view interactions] | High throughput | no | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| MON2_HUMAN | [view interactions] | High throughput | no | no |
| SARAF_HUMAN | [view interactions] | High throughput | no | no |
| CHM2A_HUMAN | [view interactions] | High throughput | no | yes |
| MFS10_HUMAN | [view interactions] | High throughput | no | yes |
| RNF26_HUMAN | [view interactions] | High throughput | no | yes |
| MYH2_HUMAN | [view interactions] | High throughput | no | yes |
| CAV2_HUMAN | [view interactions] | High throughput | no | no |
| PEX2_HUMAN | [view interactions] | High throughput | no | yes |
| FUT8_HUMAN | [view interactions] | High throughput | no | yes |
| VPS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MFF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S12A6_HUMAN | [view interactions] | High throughput | no | yes |
| PACC1_HUMAN | [view interactions] | High throughput | no | no |
| PPM1L_HUMAN | [view interactions] | High throughput | no | yes |
| MB12B_HUMAN | [view interactions] | High throughput | no | no |
| FADS3_HUMAN | [view interactions] | High throughput | no | no |
| EPS8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S35A3_HUMAN | [view interactions] | High throughput | no | yes |
| MCAT_HUMAN | [view interactions] | High throughput | no | yes |
| COBA1_HUMAN | [view interactions] | High throughput | no | no |
| ATG3_HUMAN | [view interactions] | High throughput | no | yes |
| ORML3_HUMAN | [view interactions] | High throughput | no | no |
| MBOA5_HUMAN | [view interactions] | High throughput | no | no |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP4P2_HUMAN | [view interactions] | High throughput | no | yes |
| TTC1_HUMAN | [view interactions] | High throughput | no | yes |
| COPT1_HUMAN | [view interactions] | High throughput | no | no |
| SMRCD_HUMAN | [view interactions] | High throughput | no | yes |
| ANO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDES1_HUMAN | [view interactions] | High throughput | no | no |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S12A4_HUMAN | [view interactions] | High throughput | no | yes |
| CP20A_HUMAN | [view interactions] | High throughput | no | yes |
| PTH2_HUMAN | [view interactions] | High throughput | no | yes |
| PLS3_HUMAN | [view interactions] | High throughput | no | yes |
| FADS2_HUMAN | [view interactions] | High throughput | no | yes |
| ITCH_HUMAN | [view interactions] | High throughput | no | yes |
| MRP1_HUMAN | [view interactions] | High throughput | no | no |
| GLCM_HUMAN | [view interactions] | High throughput | no | yes |
| TMED5_HUMAN | [view interactions] | High throughput | no | yes |
| NNTM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMX3_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| EPHA2_HUMAN | [view interactions] | High throughput | no | no |
| TM165_HUMAN | [view interactions] | High throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| GHITM_HUMAN | [view interactions] | High throughput | no | yes |
| AT12A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRUN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFR1_HUMAN | [view interactions] | High throughput | no | yes |
| APAF_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| STEA3_HUMAN | [view interactions] | High throughput | no | yes |
| B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
| MRP5_HUMAN | [view interactions] | High throughput | no | no |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCMC1_HUMAN | [view interactions] | High throughput | no | no |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDIPT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GALT1_HUMAN | [view interactions] | High throughput | no | yes |
| MARC2_HUMAN | [view interactions] | High throughput | no | no |
| Z3H7B_HUMAN | [view interactions] | High throughput | no | no |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| OSBL5_HUMAN | [view interactions] | High throughput | no | yes |
| UB2G2_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6A_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX10_HUMAN | [view interactions] | High throughput | no | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| GUC2D_HUMAN | [view interactions] | Computational | no | no |
| ADCY8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GCYA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ANPRB_HUMAN | [view interactions] | Computational | no | no |
| ADCY5_HUMAN | [view interactions] | Computational | no | no |
| PUR8_HUMAN | [view interactions] | Computational | no | yes |
| KAD3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ADCY3_HUMAN | [view interactions] | Computational | no | yes |
| ADCYA_HUMAN | [view interactions] | Computational | no | yes |
| ADCY4_HUMAN | [view interactions] | Computational | no | yes |
| DCK_HUMAN | [view interactions] | Computational | no | no |
| CNRG_HUMAN | [view interactions] | Computational | no | no |
| ANPRA_HUMAN | [view interactions] | Computational | no | no |
| APT_HUMAN | [view interactions] | Computational | no | yes |