EPS8_HUMAN
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context. Displays barbed-end actin capping activity when associated with ABI1, thereby regulating actin-based motility process: capping activity is auto-inhibited and inhibition is relieved upon ABI1 interaction. Also shows actin bundling activity when associated with BAIAP2, enhancing BAIAP2-dependent membrane extensions and promoting filopodial protrusions. Involved in the regulation of processes such as axonal filopodia growth, stereocilia length, dendritic cell migration and cancer cell migration and invasion. Acts as a regulator of axonal filopodia formation in neurons: in the absence of neurotrophic factors, negatively regulates axonal filopodia formation via actin-capping activity. In contrast, it is phosphorylated in the presence of BDNF leading to inhibition of its actin-capping activity and stimulation of filopodia formation. Component of a complex with WHRN and MYO15A that localizes at stereocilia tips and is required for elongation of the stereocilia actin core. Indirectly involved in cell cycle progression; its degradation following ubiquitination being required during G2 phase to promote cell shape changes. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI003807 | LIG_SH3_3 | LIG | 210 | 216 | - |
ELMI003806 | LIG_SH3_3 | LIG | 215 | 221 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in EPS8_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 37.2549 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 37.2549 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 35.2941 | 4 | no |
GO:0019900 | kinase binding | 29.4118 | 4 | no |
GO:0019901 | protein kinase binding | 25.4902 | 5 | no |
GO:0016301 | kinase activity | 23.5294 | 4 | no |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 23.5294 | 4 | no |
GO:0046872 | metal ion binding | 23.5294 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 23.5294 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 23.5294 | 5 | no |
GO:0005524 | ATP binding | 21.5686 | 5 | no |
GO:0003779 | actin binding | 13.7255 | 4 | yes |
GO:0031267 | small GTPase binding | 7.8431 | 5 | yes |
GO:0051020 | GTPase binding | 7.8431 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in EPS8_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 76.4706 | 4 | yes |
GO:0010646 | regulation of cell communication | 72.5490 | 4 | yes |
GO:0009966 | regulation of signal transduction | 62.7451 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 56.8627 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 54.9020 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 54.9020 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 54.9020 | 4 | no |
GO:0048523 | negative regulation of cellular process | 54.9020 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 49.0196 | 5 | no |
GO:0023056 | positive regulation of signaling | 49.0196 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 49.0196 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 47.0588 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 47.0588 | 4 | no |
GO:0051128 | regulation of cellular component organization | 47.0588 | 4 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 45.0980 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 45.0980 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 45.0980 | 5 | yes |
GO:0009967 | positive regulation of signal transduction | 43.1373 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 41.1765 | 6 | no |
GO:0042325 | regulation of phosphorylation | 41.1765 | 7 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 41.1765 | 5 | no |
GO:0051174 | regulation of phosphorus metabolic process | 41.1765 | 5 | no |
GO:0031399 | regulation of protein modification process | 39.2157 | 6 | no |
GO:0006996 | organelle organization | 39.2157 | 4 | yes |
GO:0001932 | regulation of protein phosphorylation | 39.2157 | 7 | no |
GO:0042127 | regulation of cell population proliferation | 37.2549 | 4 | no |
GO:0010468 | regulation of gene expression | 37.2549 | 5 | no |
GO:0007010 | cytoskeleton organization | 37.2549 | 5 | yes |
GO:0033043 | regulation of organelle organization | 37.2549 | 5 | yes |
GO:0009892 | negative regulation of metabolic process | 35.2941 | 4 | no |
GO:0022607 | cellular component assembly | 35.2941 | 4 | yes |
GO:0010562 | positive regulation of phosphorus metabolic process | 33.3333 | 6 | no |
GO:0042327 | positive regulation of phosphorylation | 33.3333 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 33.3333 | 7 | no |
GO:0051247 | positive regulation of protein metabolic process | 33.3333 | 6 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 33.3333 | 4 | yes |
GO:0071310 | cellular response to organic substance | 33.3333 | 4 | yes |
GO:0097435 | supramolecular fiber organization | 33.3333 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.3725 | 5 | no |
GO:0051049 | regulation of transport | 31.3725 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 31.3725 | 5 | no |
GO:0010941 | regulation of cell death | 31.3725 | 4 | no |
GO:0007015 | actin filament organization | 31.3725 | 5 | yes |
GO:0051130 | positive regulation of cellular component organization | 31.3725 | 5 | yes |
GO:0051493 | regulation of cytoskeleton organization | 31.3725 | 6 | yes |
GO:0031401 | positive regulation of protein modification process | 29.4118 | 7 | no |
GO:0009889 | regulation of biosynthetic process | 29.4118 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 29.4118 | 5 | no |
GO:0050804 | modulation of chemical synaptic transmission | 29.4118 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 29.4118 | 4 | no |
GO:0016192 | vesicle-mediated transport | 29.4118 | 4 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 29.4118 | 6 | no |
GO:0031344 | regulation of cell projection organization | 29.4118 | 5 | yes |
GO:0044087 | regulation of cellular component biogenesis | 29.4118 | 4 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.4118 | 6 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 29.4118 | 8 | no |
GO:0010243 | response to organonitrogen compound | 27.4510 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 27.4510 | 5 | no |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 27.4510 | 4 | no |
GO:0042981 | regulation of apoptotic process | 27.4510 | 6 | no |
GO:0043067 | regulation of programmed cell death | 27.4510 | 5 | no |
GO:0045595 | regulation of cell differentiation | 27.4510 | 4 | no |
GO:0051094 | positive regulation of developmental process | 27.4510 | 4 | no |
GO:0080134 | regulation of response to stress | 27.4510 | 4 | no |
GO:0031346 | positive regulation of cell projection organization | 27.4510 | 6 | yes |
GO:0032956 | regulation of actin cytoskeleton organization | 27.4510 | 5 | yes |
GO:0032970 | regulation of actin filament-based process | 27.4510 | 4 | yes |
GO:0030334 | regulation of cell migration | 25.4902 | 5 | no |
GO:2000145 | regulation of cell motility | 25.4902 | 4 | no |
GO:0006355 | regulation of DNA-templated transcription | 25.4902 | 6 | no |
GO:0043085 | positive regulation of catalytic activity | 25.4902 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 25.4902 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 25.4902 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 25.4902 | 6 | no |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 25.4902 | 5 | no |
GO:0008284 | positive regulation of cell population proliferation | 25.4902 | 5 | no |
GO:1901701 | cellular response to oxygen-containing compound | 25.4902 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 25.4902 | 5 | no |
GO:0030030 | cell projection organization | 25.4902 | 4 | no |
GO:0051338 | regulation of transferase activity | 25.4902 | 4 | no |
GO:0022604 | regulation of cell morphogenesis | 25.4902 | 5 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 25.4902 | 5 | yes |
GO:0051056 | regulation of small GTPase mediated signal transduction | 25.4902 | 6 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 25.4902 | 4 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 23.5294 | 6 | no |
GO:0060341 | regulation of cellular localization | 23.5294 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 23.5294 | 5 | no |
GO:0008104 | protein localization | 23.5294 | 4 | no |
GO:0030335 | positive regulation of cell migration | 23.5294 | 6 | no |
GO:0040017 | positive regulation of locomotion | 23.5294 | 4 | no |
GO:2000147 | positive regulation of cell motility | 23.5294 | 5 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 23.5294 | 5 | no |
GO:0043549 | regulation of kinase activity | 23.5294 | 5 | no |
GO:0016310 | phosphorylation | 21.5686 | 5 | no |
GO:0036211 | protein modification process | 21.5686 | 4 | no |
GO:0043412 | macromolecule modification | 21.5686 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 21.5686 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.5686 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 21.5686 | 6 | no |
GO:0051050 | positive regulation of transport | 21.5686 | 4 | no |
GO:0010638 | positive regulation of organelle organization | 21.5686 | 6 | no |
GO:0010628 | positive regulation of gene expression | 21.5686 | 6 | no |
GO:0051240 | positive regulation of multicellular organismal process | 21.5686 | 4 | no |
GO:1901699 | cellular response to nitrogen compound | 21.5686 | 4 | no |
GO:0045859 | regulation of protein kinase activity | 21.5686 | 6 | no |
GO:0032101 | regulation of response to external stimulus | 21.5686 | 4 | no |
GO:0007264 | small GTPase mediated signal transduction | 21.5686 | 4 | yes |
GO:0060491 | regulation of cell projection assembly | 21.5686 | 5 | yes |
GO:1902903 | regulation of supramolecular fiber organization | 21.5686 | 5 | yes |
GO:0007265 | Ras protein signal transduction | 19.6078 | 5 | yes |
GO:0051129 | negative regulation of cellular component organization | 19.6078 | 5 | yes |
GO:0110053 | regulation of actin filament organization | 19.6078 | 6 | yes |
GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 19.6078 | 6 | yes |
GO:0046578 | regulation of Ras protein signal transduction | 17.6471 | 7 | yes |
GO:0043254 | regulation of protein-containing complex assembly | 15.6863 | 5 | yes |
GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 15.6863 | 6 | yes |
GO:0032535 | regulation of cellular component size | 13.7255 | 4 | yes |
GO:0034097 | response to cytokine | 13.7255 | 4 | yes |
GO:0035023 | regulation of Rho protein signal transduction | 13.7255 | 8 | yes |
GO:0008360 | regulation of cell shape | 11.7647 | 6 | yes |
GO:0032271 | regulation of protein polymerization | 11.7647 | 6 | yes |
GO:0071345 | cellular response to cytokine stimulus | 11.7647 | 5 | yes |
GO:0008064 | regulation of actin polymerization or depolymerization | 9.8039 | 6 | yes |
GO:0010639 | negative regulation of organelle organization | 9.8039 | 6 | yes |
GO:0030832 | regulation of actin filament length | 9.8039 | 5 | yes |
GO:0031532 | actin cytoskeleton reorganization | 9.8039 | 4 | yes |
GO:0051017 | actin filament bundle assembly | 9.8039 | 5 | yes |
GO:0061572 | actin filament bundle organization | 9.8039 | 6 | yes |
GO:0007266 | Rho protein signal transduction | 7.8431 | 6 | yes |
GO:0016601 | Rac protein signal transduction | 7.8431 | 6 | yes |
GO:0030833 | regulation of actin filament polymerization | 7.8431 | 7 | yes |
GO:0031333 | negative regulation of protein-containing complex assembly | 7.8431 | 6 | yes |
GO:0043242 | negative regulation of protein-containing complex disassembly | 7.8431 | 6 | yes |
GO:0043244 | regulation of protein-containing complex disassembly | 7.8431 | 5 | yes |
GO:0051494 | negative regulation of cytoskeleton organization | 7.8431 | 7 | yes |
GO:1901879 | regulation of protein depolymerization | 7.8431 | 6 | yes |
GO:1901880 | negative regulation of protein depolymerization | 7.8431 | 7 | yes |
GO:1902904 | negative regulation of supramolecular fiber organization | 7.8431 | 6 | yes |
GO:0030834 | regulation of actin filament depolymerization | 5.8824 | 7 | yes |
GO:0030835 | negative regulation of actin filament depolymerization | 5.8824 | 7 | yes |
GO:0036336 | dendritic cell migration | 5.8824 | 4 | yes |
GO:0044772 | mitotic cell cycle phase transition | 5.8824 | 4 | yes |
GO:0051764 | actin crosslink formation | 5.8824 | 6 | yes |
GO:1900027 | regulation of ruffle assembly | 5.8824 | 7 | yes |
GO:1900029 | positive regulation of ruffle assembly | 5.8824 | 7 | yes |
GO:0008344 | adult locomotory behavior | 3.9216 | 4 | yes |
GO:0010458 | exit from mitosis | 3.9216 | 5 | yes |
GO:0030837 | negative regulation of actin filament polymerization | 3.9216 | 7 | yes |
GO:0032272 | negative regulation of protein polymerization | 3.9216 | 7 | yes |
GO:0048149 | behavioral response to ethanol | 3.9216 | 4 | yes |
GO:0051016 | barbed-end actin filament capping | 3.9216 | 9 | yes |
GO:0051693 | actin filament capping | 3.9216 | 8 | yes |
GO:1990823 | response to leukemia inhibitory factor | 3.9216 | 5 | yes |
GO:1990830 | cellular response to leukemia inhibitory factor | 3.9216 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in EPS8_HUMAN |
---|---|---|---|---|
DOID:1289 | neurodegenerative disease | 3.9216 | 4 | no |
DOID:331 | central nervous system disease | 3.9216 | 3 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
BI2L1_HUMAN | [view interactions] | Low throughput | no | yes |
AL7A1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
BAIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
FBXW5_HUMAN | [view interactions] | Low throughput | no | no |
ABI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSKP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LANC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LANC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ABI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
US6NL_HUMAN | [view interactions] | Low throughput | no | yes |
MK03_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CBL_HUMAN | [view interactions] | Low throughput | no | yes |
EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CD3E_HUMAN | [view interactions] | Low throughput | no | no |
DVL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITSN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SHC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SHB_HUMAN | [view interactions] | Low throughput | no | yes |
NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NMDE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NMDE3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P85A_HUMAN | [view interactions] | Low throughput | no | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXCL2_HUMAN | [view interactions] | High throughput | no | no |
XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
M3K11_HUMAN | [view interactions] | High throughput | no | yes |
NFKB2_HUMAN | [view interactions] | High throughput | no | yes |
RFXAP_HUMAN | [view interactions] | High throughput | no | no |
BCKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S27A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SF3B3_HUMAN | [view interactions] | High throughput | no | yes |
ZZZ3_HUMAN | [view interactions] | High throughput | no | yes |
CTNA3_HUMAN | [view interactions] | High throughput | no | no |
GULP1_HUMAN | [view interactions] | High throughput | no | no |
ADA22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARMC1_HUMAN | [view interactions] | High throughput | no | yes |
SCRN3_HUMAN | [view interactions] | High throughput | no | yes |
NACC2_HUMAN | [view interactions] | High throughput | no | yes |
PRSR2_HUMAN | [view interactions] | High throughput | no | yes |
TPRN_HUMAN | [view interactions] | High throughput | no | yes |
CH033_HUMAN | [view interactions] | High throughput | no | yes |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
FGL1_HUMAN | [view interactions] | High throughput | no | no |
SOX2_HUMAN | [view interactions] | High throughput | no | yes |
ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ITB5_HUMAN | [view interactions] | High throughput | no | yes |
ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
INSR_HUMAN | [view interactions] | High throughput | no | yes |
HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
TYDP2_HUMAN | [view interactions] | High throughput | no | no |
XAGE2_HUMAN | [view interactions] | High throughput | no | no |
CF141_HUMAN | [view interactions] | High throughput | no | no |
RCAN3_HUMAN | [view interactions] | High throughput | no | no |
RSP14_HUMAN | [view interactions] | High throughput | no | no |
IPSP_HUMAN | [view interactions] | High throughput | no | no |
HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GOG8D_HUMAN | [view interactions] | High throughput | no | no |
BYST_HUMAN | [view interactions] | High throughput | no | yes |
PI5PA_HUMAN | [view interactions] | High throughput | no | no |
SMCE1_HUMAN | [view interactions] | High throughput | no | yes |
BORC6_HUMAN | [view interactions] | High throughput | no | yes |
CS025_HUMAN | [view interactions] | High throughput | no | no |
RM20_HUMAN | [view interactions] | High throughput | no | yes |
MYO15_HUMAN | [view interactions] | High throughput | no | no |
IDLC_HUMAN | [view interactions] | High throughput | no | no |
BL1S6_HUMAN | [view interactions] | High throughput | no | yes |
CC85B_HUMAN | [view interactions] | High throughput | no | yes |
AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
PCM1_HUMAN | [view interactions] | High throughput | no | yes |
HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
TEX28_HUMAN | [view interactions] | High throughput | no | no |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
ANR28_HUMAN | [view interactions] | High throughput | no | no |
EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ROR1_HUMAN | [view interactions] | High throughput | no | no |
TANK_HUMAN | [view interactions] | High throughput | no | yes |
MTG8_HUMAN | [view interactions] | High throughput | no | yes |
MDC1_HUMAN | [view interactions] | High throughput | no | yes |
AMPD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
NUPR1_HUMAN | [view interactions] | High throughput | no | no |
DDX58_HUMAN | [view interactions] | High throughput | no | yes |
MRP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GPC5B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MND1_HUMAN | [view interactions] | High throughput | no | no |
MEIS2_HUMAN | [view interactions] | High throughput | no | yes |
MILR1_HUMAN | [view interactions] | High throughput | no | no |
MS18B_HUMAN | [view interactions] | High throughput | no | no |
TMM51_HUMAN | [view interactions] | High throughput | no | yes |
TYW3_HUMAN | [view interactions] | High throughput | no | yes |
LYRM4_HUMAN | [view interactions] | High throughput | no | yes |
ETFA_HUMAN | [view interactions] | High throughput | no | yes |
IBP5_HUMAN | [view interactions] | High throughput | no | no |
PDE2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ABRX2_HUMAN | [view interactions] | High throughput | no | yes |
RHG15_HUMAN | [view interactions] | High throughput | no | no |
RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHG26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CHIO_HUMAN | [view interactions] | High throughput | no | yes |
RHG42_HUMAN | [view interactions] | High throughput | no | yes |
FBF1_HUMAN | [view interactions] | High throughput | no | no |
TBKB1_HUMAN | [view interactions] | High throughput | no | no |
GLI2_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRIC1_HUMAN | [view interactions] | High throughput | no | yes |
PRIC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RGF1B_HUMAN | [view interactions] | High throughput | no | no |
RASF8_HUMAN | [view interactions] | High throughput | no | yes |
SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SRGP1_HUMAN | [view interactions] | High throughput | no | no |
TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACTC_HUMAN | [view interactions] | High throughput | no | no |
BICD1_HUMAN | [view interactions] | High throughput | no | yes |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CK052_HUMAN | [view interactions] | High throughput | no | no |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IFM3_HUMAN | [view interactions] | High throughput | no | yes |
PALLD_HUMAN | [view interactions] | Computational | no | yes |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PI3R6_HUMAN | [view interactions] | Computational | no | yes |
PK3CB_HUMAN | [view interactions] | Computational | no | yes |
WHRN_HUMAN | [view interactions] | Computational | no | no |
PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAB5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ABL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PK3CG_HUMAN | [view interactions] | Computational | no | yes |
EGF_HUMAN | [view interactions] | Computational | no | no |