Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

LANC2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in LANC2_HUMAN
GO:0017076 purine nucleotide binding 35.7143 4 yes
GO:0032555 purine ribonucleotide binding 35.7143 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 35.7143 4 yes
GO:0019900 kinase binding 35.7143 4 no
GO:0019901 protein kinase binding 35.7143 5 no
GO:0042803 protein homodimerization activity 28.5714 4 no
GO:0005524 ATP binding 21.4286 5 yes
GO:0005525 GTP binding 21.4286 5 yes
GO:0019001 guanyl nucleotide binding 21.4286 5 yes
GO:0030554 adenyl nucleotide binding 21.4286 5 yes
GO:0032559 adenyl ribonucleotide binding 21.4286 5 yes
GO:0032561 guanyl ribonucleotide binding 21.4286 5 yes
GO:0035091 phosphatidylinositol binding 21.4286 4 yes
GO:1901981 phosphatidylinositol phosphate binding 21.4286 5 yes
GO:0003779 actin binding 21.4286 4 no
GO:0019902 phosphatase binding 21.4286 4 no
GO:0019903 protein phosphatase binding 21.4286 5 no
GO:0046982 protein heterodimerization activity 21.4286 4 no
GO:0003677 DNA binding 21.4286 4 no
GO:0003690 double-stranded DNA binding 21.4286 5 no
GO:0043565 sequence-specific DNA binding 21.4286 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in LANC2_HUMAN
GO:0048522 positive regulation of cellular process 85.7143 4 yes
GO:0031323 regulation of cellular metabolic process 71.4286 4 yes
GO:0048523 negative regulation of cellular process 64.2857 4 yes
GO:0006996 organelle organization 64.2857 4 no
GO:0051128 regulation of cellular component organization 64.2857 4 no
GO:0009966 regulation of signal transduction 57.1429 4 yes
GO:0010646 regulation of cell communication 57.1429 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 57.1429 4 yes
GO:0060255 regulation of macromolecule metabolic process 57.1429 4 yes
GO:0080090 regulation of primary metabolic process 57.1429 4 yes
GO:0031344 regulation of cell projection organization 57.1429 5 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0022607 cellular component assembly 50.0000 4 no
GO:0033043 regulation of organelle organization 50.0000 5 no
GO:0051130 positive regulation of cellular component organization 50.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 50.0000 6 no
GO:0051094 positive regulation of developmental process 50.0000 4 no
GO:0009893 positive regulation of metabolic process 50.0000 4 no
GO:0031325 positive regulation of cellular metabolic process 50.0000 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 42.8571 5 no
GO:0051174 regulation of phosphorus metabolic process 42.8571 5 no
GO:0051247 positive regulation of protein metabolic process 42.8571 6 no
GO:0009892 negative regulation of metabolic process 42.8571 4 yes
GO:0031324 negative regulation of cellular metabolic process 42.8571 5 yes
GO:0048584 positive regulation of response to stimulus 42.8571 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 42.8571 4 no
GO:0030030 cell projection organization 42.8571 4 no
GO:0031346 positive regulation of cell projection organization 42.8571 6 no
GO:0032880 regulation of protein localization 42.8571 5 no
GO:0060341 regulation of cellular localization 42.8571 4 no
GO:0097435 supramolecular fiber organization 42.8571 4 no
GO:0120036 plasma membrane bounded cell projection organization 42.8571 5 no
GO:1903829 positive regulation of protein localization 42.8571 5 no
GO:0008104 protein localization 42.8571 4 no
GO:0051240 positive regulation of multicellular organismal process 42.8571 4 no
GO:0009894 regulation of catabolic process 42.8571 4 no
GO:0010604 positive regulation of macromolecule metabolic process 42.8571 5 no
GO:0019220 regulation of phosphate metabolic process 42.8571 6 no
GO:0031329 regulation of cellular catabolic process 42.8571 5 no
GO:0031399 regulation of protein modification process 42.8571 6 no
GO:0043412 macromolecule modification 35.7143 4 no
GO:0043549 regulation of kinase activity 35.7143 5 no
GO:0045595 regulation of cell differentiation 35.7143 4 no
GO:0045597 positive regulation of cell differentiation 35.7143 5 no
GO:0045937 positive regulation of phosphate metabolic process 35.7143 7 no
GO:0051129 negative regulation of cellular component organization 35.7143 5 no
GO:0051338 regulation of transferase activity 35.7143 4 no
GO:0051347 positive regulation of transferase activity 35.7143 5 no
GO:0071310 cellular response to organic substance 35.7143 4 no
GO:1902531 regulation of intracellular signal transduction 35.7143 5 no
GO:0010468 regulation of gene expression 35.7143 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 35.7143 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 35.7143 5 yes
GO:0007010 cytoskeleton organization 35.7143 5 no
GO:0030334 regulation of cell migration 35.7143 5 no
GO:0030335 positive regulation of cell migration 35.7143 6 no
GO:0040017 positive regulation of locomotion 35.7143 4 no
GO:0044087 regulation of cellular component biogenesis 35.7143 4 no
GO:0051049 regulation of transport 35.7143 4 no
GO:0051493 regulation of cytoskeleton organization 35.7143 6 no
GO:2000145 regulation of cell motility 35.7143 4 no
GO:2000147 positive regulation of cell motility 35.7143 5 no
GO:1901701 cellular response to oxygen-containing compound 35.7143 4 no
GO:2000026 regulation of multicellular organismal development 35.7143 4 no
GO:0010562 positive regulation of phosphorus metabolic process 35.7143 6 no
GO:0033674 positive regulation of kinase activity 35.7143 6 no
GO:0036211 protein modification process 35.7143 4 no
GO:0042325 regulation of phosphorylation 35.7143 7 no
GO:0042327 positive regulation of phosphorylation 35.7143 8 no
GO:0043085 positive regulation of catalytic activity 35.7143 4 no
GO:0045859 regulation of protein kinase activity 28.5714 6 no
GO:0045860 positive regulation of protein kinase activity 28.5714 7 no
GO:0045862 positive regulation of proteolysis 28.5714 7 no
GO:0048638 regulation of developmental growth 28.5714 4 no
GO:0048878 chemical homeostasis 28.5714 4 no
GO:0051336 regulation of hydrolase activity 28.5714 4 no
GO:0051345 positive regulation of hydrolase activity 28.5714 5 no
GO:0051960 regulation of nervous system development 28.5714 5 no
GO:0060284 regulation of cell development 28.5714 5 no
GO:0080134 regulation of response to stress 28.5714 4 no
GO:0080135 regulation of cellular response to stress 28.5714 4 no
GO:1902903 regulation of supramolecular fiber organization 28.5714 5 no
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 no
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 no
GO:0006355 regulation of DNA-templated transcription 28.5714 6 yes
GO:0009889 regulation of biosynthetic process 28.5714 4 yes
GO:0009967 positive regulation of signal transduction 28.5714 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 28.5714 5 yes
GO:0010647 positive regulation of cell communication 28.5714 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.5714 5 yes
GO:0023056 positive regulation of signaling 28.5714 4 yes
GO:0031326 regulation of cellular biosynthetic process 28.5714 5 yes
GO:0051252 regulation of RNA metabolic process 28.5714 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 28.5714 7 yes
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 yes
GO:0007015 actin filament organization 28.5714 5 no
GO:0022604 regulation of cell morphogenesis 28.5714 5 no
GO:0031175 neuron projection development 28.5714 6 no
GO:0032956 regulation of actin cytoskeleton organization 28.5714 5 no
GO:0032970 regulation of actin filament-based process 28.5714 4 no
GO:0042127 regulation of cell population proliferation 28.5714 4 no
GO:0044089 positive regulation of cellular component biogenesis 28.5714 5 no
GO:0051050 positive regulation of transport 28.5714 4 no
GO:0070201 regulation of establishment of protein localization 28.5714 6 no
GO:0006915 apoptotic process 28.5714 4 no
GO:0010941 regulation of cell death 28.5714 4 no
GO:0015031 protein transport 28.5714 4 no
GO:0051726 regulation of cell cycle 28.5714 4 no
GO:0071702 organic substance transport 28.5714 4 no
GO:0071705 nitrogen compound transport 28.5714 4 no
GO:0001558 regulation of cell growth 28.5714 4 no
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0001934 positive regulation of protein phosphorylation 28.5714 8 no
GO:0009896 positive regulation of catabolic process 28.5714 5 no
GO:0010038 response to metal ion 28.5714 4 no
GO:0010506 regulation of autophagy 28.5714 6 no
GO:0010639 negative regulation of organelle organization 28.5714 6 no
GO:0030162 regulation of proteolysis 28.5714 6 no
GO:0031331 positive regulation of cellular catabolic process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0033365 protein localization to organelle 28.5714 5 no
GO:0034762 regulation of transmembrane transport 28.5714 4 no
GO:0043269 regulation of ion transport 28.5714 5 no
GO:0043393 regulation of protein binding 21.4286 4 no
GO:0045834 positive regulation of lipid metabolic process 21.4286 5 no
GO:0045893 positive regulation of DNA-templated transcription 21.4286 7 no
GO:0045927 positive regulation of growth 21.4286 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 21.4286 6 no
GO:0045936 negative regulation of phosphate metabolic process 21.4286 7 no
GO:0048585 negative regulation of response to stimulus 21.4286 4 no
GO:0048639 positive regulation of developmental growth 21.4286 5 no
GO:0051051 negative regulation of transport 21.4286 4 no
GO:0051248 negative regulation of protein metabolic process 21.4286 6 no
GO:0051254 positive regulation of RNA metabolic process 21.4286 6 no
GO:0052547 regulation of peptidase activity 21.4286 5 no
GO:0052548 regulation of endopeptidase activity 21.4286 6 no
GO:0070848 response to growth factor 21.4286 4 no
GO:0071241 cellular response to inorganic substance 21.4286 4 no
GO:0071248 cellular response to metal ion 21.4286 5 no
GO:0071363 cellular response to growth factor stimulus 21.4286 5 no
GO:0071417 cellular response to organonitrogen compound 21.4286 4 no
GO:1901214 regulation of neuron death 21.4286 5 no
GO:1901652 response to peptide 21.4286 4 no
GO:1901699 cellular response to nitrogen compound 21.4286 4 no
GO:1902680 positive regulation of RNA biosynthetic process 21.4286 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 21.4286 8 no
GO:1990090 cellular response to nerve growth factor stimulus 21.4286 4 no
GO:2000112 regulation of cellular macromolecule biosynthetic process 21.4286 6 no
GO:2000116 regulation of cysteine-type endopeptidase activity 21.4286 7 no
GO:0032271 regulation of protein polymerization 21.4286 6 no
GO:0043254 regulation of protein-containing complex assembly 21.4286 5 no
GO:0006873 cellular ion homeostasis 21.4286 4 no
GO:0006874 cellular calcium ion homeostasis 21.4286 7 no
GO:0006875 cellular metal ion homeostasis 21.4286 6 no
GO:0022898 regulation of transmembrane transporter activity 21.4286 4 no
GO:0030003 cellular cation homeostasis 21.4286 5 no
GO:0032412 regulation of ion transmembrane transporter activity 21.4286 5 no
GO:0034765 regulation of ion transmembrane transport 21.4286 5 no
GO:0044057 regulation of system process 21.4286 4 no
GO:0050801 ion homeostasis 21.4286 5 no
GO:0055065 metal ion homeostasis 21.4286 7 no
GO:0055074 calcium ion homeostasis 21.4286 8 no
GO:0055080 cation homeostasis 21.4286 6 no
GO:0072503 cellular divalent inorganic cation homeostasis 21.4286 6 no
GO:0072507 divalent inorganic cation homeostasis 21.4286 7 no
GO:0098771 inorganic ion homeostasis 21.4286 6 no
GO:1904062 regulation of cation transmembrane transport 21.4286 6 no
GO:0043933 protein-containing complex organization 21.4286 4 no
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 21.4286 8 no
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 21.4286 9 no
GO:0050890 cognition 21.4286 4 no
GO:0050905 neuromuscular process 21.4286 4 no
GO:0065003 protein-containing complex assembly 21.4286 5 no
GO:0010720 positive regulation of cell development 21.4286 6 no
GO:0050767 regulation of neurogenesis 21.4286 6 no
GO:0050769 positive regulation of neurogenesis 21.4286 6 no
GO:0051962 positive regulation of nervous system development 21.4286 5 no
GO:0070925 organelle assembly 21.4286 5 no
GO:1902905 positive regulation of supramolecular fiber organization 21.4286 6 no
GO:0002684 positive regulation of immune system process 21.4286 4 no
GO:0002685 regulation of leukocyte migration 21.4286 4 no
GO:0007264 small GTPase mediated signal transduction 21.4286 4 no
GO:0007265 Ras protein signal transduction 21.4286 5 no
GO:0008284 positive regulation of cell population proliferation 21.4286 5 no
GO:0008360 regulation of cell shape 21.4286 6 no
GO:0030155 regulation of cell adhesion 21.4286 4 no
GO:0050865 regulation of cell activation 21.4286 4 no
GO:0051222 positive regulation of protein transport 21.4286 5 no
GO:0051223 regulation of protein transport 21.4286 5 no
GO:0060491 regulation of cell projection assembly 21.4286 5 no
GO:0060627 regulation of vesicle-mediated transport 21.4286 4 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 21.4286 6 no
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 21.4286 6 no
GO:1904951 positive regulation of establishment of protein localization 21.4286 6 no
GO:2000377 regulation of reactive oxygen species metabolic process 21.4286 5 no
GO:0000302 response to reactive oxygen species 21.4286 4 no
GO:0006886 intracellular protein transport 21.4286 4 no
GO:0010632 regulation of epithelial cell migration 21.4286 4 no
GO:0010634 positive regulation of epithelial cell migration 21.4286 5 no
GO:0010942 positive regulation of cell death 21.4286 5 no
GO:0034599 cellular response to oxidative stress 21.4286 4 no
GO:0034614 cellular response to reactive oxygen species 21.4286 5 no
GO:0042981 regulation of apoptotic process 21.4286 6 no
GO:0043067 regulation of programmed cell death 21.4286 5 no
GO:0062197 cellular response to chemical stress 21.4286 4 no
GO:0006417 regulation of translation 21.4286 6 no
GO:0006468 protein phosphorylation 21.4286 5 no
GO:0006796 phosphate-containing compound metabolic process 21.4286 4 no
GO:0007346 regulation of mitotic cell cycle 21.4286 5 no
GO:0009891 positive regulation of biosynthetic process 21.4286 5 no
GO:0009968 negative regulation of signal transduction 21.4286 5 no
GO:0010243 response to organonitrogen compound 21.4286 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 21.4286 6 no
GO:0010563 negative regulation of phosphorus metabolic process 21.4286 6 no
GO:0010608 post-transcriptional regulation of gene expression 21.4286 6 no
GO:0010628 positive regulation of gene expression 21.4286 6 no
GO:0010629 negative regulation of gene expression 21.4286 6 no
GO:0010648 negative regulation of cell communication 21.4286 5 no
GO:0010821 regulation of mitochondrion organization 21.4286 6 no
GO:0010823 negative regulation of mitochondrion organization 21.4286 7 no
GO:0010975 regulation of neuron projection development 21.4286 7 no
GO:0016310 phosphorylation 21.4286 5 no
GO:0019216 regulation of lipid metabolic process 21.4286 5 no
GO:0023057 negative regulation of signaling 21.4286 4 no
GO:0030307 positive regulation of cell growth 21.4286 5 no
GO:0031328 positive regulation of cellular biosynthetic process 21.4286 6 no
GO:0031400 negative regulation of protein modification process 21.4286 7 no
GO:0031929 TOR signaling 21.4286 4 no
GO:0034097 response to cytokine 21.4286 4 no
GO:0034248 regulation of cellular amide metabolic process 21.4286 5 no
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 21.4286 8 no
GO:0009890 negative regulation of biosynthetic process 14.2857 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 14.2857 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 14.2857 6 yes
GO:0045892 negative regulation of DNA-templated transcription 14.2857 7 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 14.2857 6 yes
GO:0051253 negative regulation of RNA metabolic process 14.2857 6 yes
GO:1902679 negative regulation of RNA biosynthetic process 14.2857 7 yes
GO:1903507 negative regulation of nucleic acid-templated transcription 14.2857 8 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
EPS8_HUMAN [view entry] [view interactions] Low throughput yes yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
MP2K5_HUMAN [view interactions] High throughput no yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
OTUD5_HUMAN [view interactions] High throughput no yes
FEZ1_HUMAN [view interactions] High throughput no no
PCGF2_HUMAN [view interactions] High throughput no no
KCNJ5_HUMAN [view interactions] High throughput no yes
DOK2_HUMAN [view interactions] High throughput no no
MINY3_HUMAN [view interactions] High throughput no yes
GSTM3_HUMAN [view entry] [view interactions] High throughput yes yes
GMFG_HUMAN [view interactions] High throughput no yes
TE2IP_HUMAN [view interactions] High throughput no yes
APBB1_HUMAN [view interactions] High throughput no yes
APBP2_HUMAN [view interactions] High throughput no yes
TDRKH_HUMAN [view interactions] High throughput no no
CIAO1_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
TERF2_HUMAN [view interactions] High throughput no yes
SIAH1_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
TFE2_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
MERL_HUMAN [view interactions] High throughput no yes
AIRE_HUMAN [view interactions] High throughput no no
PVR_HUMAN [view interactions] High throughput no yes
PPIE_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
MTOR_HUMAN [view entry] [view interactions] High throughput yes yes
RICTR_HUMAN [view interactions] High throughput no yes
RPTOR_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
EYA4_HUMAN [view interactions] High throughput no yes
MTMR4_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
WWP2_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
CC018_HUMAN [view interactions] High throughput no yes
ANR39_HUMAN [view interactions] High throughput no no
SPXN4_HUMAN [view interactions] High throughput no no
TM263_HUMAN [view interactions] High throughput no yes
LAIR2_HUMAN [view interactions] High throughput no no
PP14D_HUMAN [view interactions] High throughput no no
IFT20_HUMAN [view interactions] High throughput no yes
CD6_HUMAN [view interactions] High throughput no no
APBA1_HUMAN [view interactions] High throughput no no
CC85A_HUMAN [view interactions] High throughput no yes
PAGE1_HUMAN [view interactions] High throughput no no
TPM4_HUMAN [view entry] [view interactions] High throughput yes yes
RT18C_HUMAN [view interactions] High throughput no yes
TTHY_HUMAN [view interactions] High throughput no no
AT7L1_HUMAN [view interactions] High throughput no yes
MTPN_HUMAN [view interactions] High throughput no yes
HYPM_HUMAN [view interactions] High throughput no no
F133A_HUMAN [view interactions] High throughput no no
E41L5_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
BAP1_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
RHOU_HUMAN [view interactions] High throughput no no
MON1B_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes