Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

LANC2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in LANC2_HUMAN
GO:0043168 anion binding 33.3333 4 yes
GO:0000166 nucleotide binding 27.7778 4 yes
GO:0017076 purine nucleotide binding 27.7778 5 yes
GO:0032555 purine ribonucleotide binding 27.7778 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 27.7778 4 yes
GO:0019900 kinase binding 27.7778 4 no
GO:0003779 actin binding 22.2222 4 no
GO:0042803 protein homodimerization activity 22.2222 4 no
GO:0019901 protein kinase binding 22.2222 5 no
GO:0031625 ubiquitin protein ligase binding 22.2222 5 no
GO:0043169 cation binding 22.2222 4 no
GO:0044389 ubiquitin-like protein ligase binding 22.2222 4 no
GO:0046872 metal ion binding 22.2222 5 no
GO:0005524 ATP binding 16.6667 5 yes
GO:0005525 GTP binding 16.6667 5 yes
GO:0019001 guanyl nucleotide binding 16.6667 6 yes
GO:0030554 adenyl nucleotide binding 16.6667 6 yes
GO:0032559 adenyl ribonucleotide binding 16.6667 5 yes
GO:0032561 guanyl ribonucleotide binding 16.6667 5 yes
GO:0035091 phosphatidylinositol binding 16.6667 4 yes
GO:1901981 phosphatidylinositol phosphate binding 16.6667 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in LANC2_HUMAN
GO:0048522 positive regulation of cellular process 88.8889 4 yes
GO:0031323 regulation of cellular metabolic process 72.2222 4 yes
GO:0048523 negative regulation of cellular process 72.2222 4 yes
GO:0051128 regulation of cellular component organization 72.2222 4 no
GO:0060255 regulation of macromolecule metabolic process 66.6667 4 yes
GO:0009966 regulation of signal transduction 61.1111 4 yes
GO:0010646 regulation of cell communication 61.1111 4 yes
GO:0048584 positive regulation of response to stimulus 61.1111 4 yes
GO:0080090 regulation of primary metabolic process 61.1111 4 yes
GO:0009892 negative regulation of metabolic process 55.5556 4 yes
GO:0031324 negative regulation of cellular metabolic process 55.5556 5 yes
GO:0022607 cellular component assembly 55.5556 4 no
GO:0051130 positive regulation of cellular component organization 55.5556 5 no
GO:0009893 positive regulation of metabolic process 55.5556 4 no
GO:0009889 regulation of biosynthetic process 50.0000 4 yes
GO:0010468 regulation of gene expression 50.0000 6 yes
GO:0010556 regulation of macromolecule biosynthetic process 50.0000 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 50.0000 5 yes
GO:0031326 regulation of cellular biosynthetic process 50.0000 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 no
GO:0051246 regulation of protein metabolic process 50.0000 5 no
GO:0009890 negative regulation of biosynthetic process 44.4444 5 yes
GO:0009967 positive regulation of signal transduction 44.4444 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 44.4444 6 yes
GO:0010647 positive regulation of cell communication 44.4444 5 yes
GO:0023056 positive regulation of signaling 44.4444 4 yes
GO:0031327 negative regulation of cellular biosynthetic process 44.4444 6 yes
GO:0031344 regulation of cell projection organization 44.4444 5 no
GO:0097435 supramolecular fiber organization 44.4444 4 no
GO:0006996 organelle organization 44.4444 4 no
GO:0009894 regulation of catabolic process 44.4444 4 no
GO:0031325 positive regulation of cellular metabolic process 44.4444 5 no
GO:0036211 protein modification process 44.4444 4 no
GO:0043412 macromolecule modification 44.4444 4 no
GO:0031399 regulation of protein modification process 44.4444 6 no
GO:0032880 regulation of protein localization 44.4444 5 no
GO:0051247 positive regulation of protein metabolic process 44.4444 6 no
GO:0060341 regulation of cellular localization 44.4444 4 no
GO:0030030 cell projection organization 44.4444 4 no
GO:0006355 regulation of DNA-templated transcription 38.8889 7 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 38.8889 5 yes
GO:0051252 regulation of RNA metabolic process 38.8889 5 yes
GO:2001141 regulation of RNA biosynthetic process 38.8889 6 yes
GO:0031346 positive regulation of cell projection organization 38.8889 6 no
GO:0044087 regulation of cellular component biogenesis 38.8889 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 38.8889 6 no
GO:1902531 regulation of intracellular signal transduction 38.8889 5 no
GO:0008104 protein localization 38.8889 4 no
GO:0019220 regulation of phosphate metabolic process 38.8889 6 no
GO:0051049 regulation of transport 38.8889 4 no
GO:0051094 positive regulation of developmental process 38.8889 4 no
GO:0051174 regulation of phosphorus metabolic process 38.8889 5 no
GO:0022603 regulation of anatomical structure morphogenesis 33.3333 4 no
GO:0033043 regulation of organelle organization 33.3333 5 no
GO:0051129 negative regulation of cellular component organization 33.3333 5 no
GO:0141124 intracellular signaling cassette 33.3333 4 no
GO:0009896 positive regulation of catabolic process 33.3333 5 no
GO:0031329 regulation of cellular catabolic process 33.3333 5 no
GO:0001558 regulation of cell growth 33.3333 4 no
GO:0009057 macromolecule catabolic process 33.3333 4 no
GO:0010629 negative regulation of gene expression 33.3333 7 no
GO:0030307 positive regulation of cell growth 33.3333 5 no
GO:0031401 positive regulation of protein modification process 33.3333 7 no
GO:0042325 regulation of phosphorylation 33.3333 7 no
GO:0043933 protein-containing complex organization 33.3333 4 no
GO:0045927 positive regulation of growth 33.3333 4 no
GO:0080134 regulation of response to stress 33.3333 4 no
GO:1901701 cellular response to oxygen-containing compound 33.3333 4 no
GO:1903829 positive regulation of protein localization 33.3333 5 no
GO:0051240 positive regulation of multicellular organismal process 33.3333 4 no
GO:2000026 regulation of multicellular organismal development 33.3333 4 no
GO:0002684 positive regulation of immune system process 33.3333 4 no
GO:0006915 apoptotic process 33.3333 4 no
GO:0030334 regulation of cell migration 33.3333 5 no
GO:0030335 positive regulation of cell migration 33.3333 6 no
GO:0040017 positive regulation of locomotion 33.3333 4 no
GO:2000145 regulation of cell motility 33.3333 4 no
GO:2000147 positive regulation of cell motility 33.3333 5 no
GO:0051726 regulation of cell cycle 33.3333 4 no
GO:0042127 regulation of cell population proliferation 33.3333 4 no
GO:0007015 actin filament organization 27.7778 5 no
GO:0010639 negative regulation of organelle organization 27.7778 6 no
GO:0071310 cellular response to organic substance 27.7778 4 no
GO:1902903 regulation of supramolecular fiber organization 27.7778 5 no
GO:0010506 regulation of autophagy 27.7778 6 no
GO:0001932 regulation of protein phosphorylation 27.7778 7 no
GO:0006357 regulation of transcription by RNA polymerase II 27.7778 8 no
GO:0006508 proteolysis 27.7778 4 no
GO:0009891 positive regulation of biosynthetic process 27.7778 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 27.7778 6 no
GO:0030163 protein catabolic process 27.7778 4 no
GO:0031328 positive regulation of cellular biosynthetic process 27.7778 6 no
GO:0033365 protein localization to organelle 27.7778 5 no
GO:0042981 regulation of apoptotic process 27.7778 5 no
GO:0043067 regulation of programmed cell death 27.7778 4 no
GO:0043549 regulation of kinase activity 27.7778 5 no
GO:0045893 positive regulation of DNA-templated transcription 27.7778 8 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 27.7778 5 no
GO:0048638 regulation of developmental growth 27.7778 4 no
GO:0050804 modulation of chemical synaptic transmission 27.7778 5 no
GO:0051254 positive regulation of RNA metabolic process 27.7778 6 no
GO:0051338 regulation of transferase activity 27.7778 4 no
GO:0062197 cellular response to chemical stress 27.7778 4 no
GO:0065003 protein-containing complex assembly 27.7778 5 no
GO:0070201 regulation of establishment of protein localization 27.7778 6 no
GO:0099177 regulation of trans-synaptic signaling 27.7778 4 no
GO:1901565 organonitrogen compound catabolic process 27.7778 4 no
GO:1902533 positive regulation of intracellular signal transduction 27.7778 6 no
GO:1902680 positive regulation of RNA biosynthetic process 27.7778 7 no
GO:0010562 positive regulation of phosphorus metabolic process 27.7778 6 no
GO:0042327 positive regulation of phosphorylation 27.7778 8 no
GO:0045937 positive regulation of phosphate metabolic process 27.7778 7 no
GO:0120036 plasma membrane bounded cell projection organization 27.7778 5 no
GO:0045595 regulation of cell differentiation 27.7778 4 no
GO:0030155 regulation of cell adhesion 27.7778 4 no
GO:0032101 regulation of response to external stimulus 27.7778 4 no
GO:0008284 positive regulation of cell population proliferation 27.7778 5 no
GO:0050807 regulation of synapse organization 27.7778 5 no
GO:0045892 negative regulation of DNA-templated transcription 22.2222 8 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 22.2222 5 yes
GO:0051253 negative regulation of RNA metabolic process 22.2222 6 yes
GO:1902679 negative regulation of RNA biosynthetic process 22.2222 7 yes
GO:0034097 response to cytokine 22.2222 4 no
GO:0044089 positive regulation of cellular component biogenesis 22.2222 5 no
GO:0051493 regulation of cytoskeleton organization 22.2222 6 no
GO:0060491 regulation of cell projection assembly 22.2222 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 22.2222 6 no
GO:0031331 positive regulation of cellular catabolic process 22.2222 6 no
GO:0043687 post-translational protein modification 22.2222 5 no
GO:0071702 organic substance transport 22.2222 4 no
GO:0071705 nitrogen compound transport 22.2222 4 no
GO:0006109 regulation of carbohydrate metabolic process 22.2222 5 no
GO:0006511 ubiquitin-dependent protein catabolic process 22.2222 7 no
GO:0009968 negative regulation of signal transduction 22.2222 5 no
GO:0010038 response to metal ion 22.2222 4 no
GO:0010243 response to organonitrogen compound 22.2222 4 no
GO:0010563 negative regulation of phosphorus metabolic process 22.2222 6 no
GO:0010628 positive regulation of gene expression 22.2222 7 no
GO:0010638 positive regulation of organelle organization 22.2222 6 no
GO:0010648 negative regulation of cell communication 22.2222 5 no
GO:0019941 modification-dependent protein catabolic process 22.2222 6 no
GO:0023057 negative regulation of signaling 22.2222 4 no
GO:0030162 regulation of proteolysis 22.2222 6 no
GO:0031400 negative regulation of protein modification process 22.2222 7 no
GO:0034599 cellular response to oxidative stress 22.2222 4 no
GO:0043393 regulation of protein binding 22.2222 4 no
GO:0043632 modification-dependent macromolecule catabolic process 22.2222 5 no
GO:0045862 positive regulation of proteolysis 22.2222 7 no
GO:0045936 negative regulation of phosphate metabolic process 22.2222 7 no
GO:0045944 positive regulation of transcription by RNA polymerase II 22.2222 9 no
GO:0048585 negative regulation of response to stimulus 22.2222 4 no
GO:0048639 positive regulation of developmental growth 22.2222 5 no
GO:0050890 cognition 22.2222 4 no
GO:0050905 neuromuscular process 22.2222 4 no
GO:0051050 positive regulation of transport 22.2222 4 no
GO:0051051 negative regulation of transport 22.2222 4 no
GO:0051248 negative regulation of protein metabolic process 22.2222 6 no
GO:0051603 proteolysis involved in protein catabolic process 22.2222 5 no
GO:0062012 regulation of small molecule metabolic process 22.2222 4 no
GO:0071417 cellular response to organonitrogen compound 22.2222 4 no
GO:1901699 cellular response to nitrogen compound 22.2222 4 no
GO:1902532 negative regulation of intracellular signal transduction 22.2222 6 no
GO:1903828 negative regulation of protein localization 22.2222 5 no
GO:0001934 positive regulation of protein phosphorylation 22.2222 8 no
GO:0034762 regulation of transmembrane transport 22.2222 4 no
GO:0043085 positive regulation of catalytic activity 22.2222 4 no
GO:0007010 cytoskeleton organization 22.2222 5 no
GO:0010975 regulation of neuron projection development 22.2222 7 no
GO:0045597 positive regulation of cell differentiation 22.2222 5 no
GO:0051960 regulation of nervous system development 22.2222 5 no
GO:0060284 regulation of cell development 22.2222 5 no
GO:0006468 protein phosphorylation 22.2222 5 no
GO:0006796 phosphate-containing compound metabolic process 22.2222 4 no
GO:0016310 phosphorylation 22.2222 5 no
GO:0010564 regulation of cell cycle process 22.2222 5 no
GO:1901987 regulation of cell cycle phase transition 22.2222 6 no
GO:0007346 regulation of mitotic cell cycle 22.2222 5 no
GO:0032103 positive regulation of response to external stimulus 22.2222 5 no
GO:0002685 regulation of leukocyte migration 22.2222 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
EPS8_HUMAN [view entry] [view interactions] Low throughput yes yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
MP2K5_HUMAN [view interactions] High throughput no yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
OTUD5_HUMAN [view interactions] High throughput no yes
FEZ1_HUMAN [view interactions] High throughput no no
PCGF2_HUMAN [view interactions] High throughput no no
KCNJ5_HUMAN [view interactions] High throughput no yes
DOK2_HUMAN [view interactions] High throughput no no
MINY3_HUMAN [view interactions] High throughput no yes
GSTM3_HUMAN [view entry] [view interactions] High throughput yes yes
GMFG_HUMAN [view interactions] High throughput no yes
TE2IP_HUMAN [view interactions] High throughput no yes
APBB1_HUMAN [view entry] [view interactions] High throughput yes yes
SIM26_HUMAN [view interactions] High throughput no no
APBP2_HUMAN [view interactions] High throughput no yes
TDRKH_HUMAN [view interactions] High throughput no no
CIAO1_HUMAN [view interactions] High throughput no yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
TERF2_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
SIAH1_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
TFE2_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
MERL_HUMAN [view interactions] High throughput no yes
AIRE_HUMAN [view interactions] High throughput no no
PVR_HUMAN [view interactions] High throughput no yes
PPIE_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
MTOR_HUMAN [view entry] [view interactions] High throughput yes yes
RICTR_HUMAN [view interactions] High throughput no yes
RPTOR_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
EYA4_HUMAN [view interactions] High throughput no yes
MTMR4_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
WWP2_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
CC018_HUMAN [view interactions] High throughput no yes
ANR39_HUMAN [view interactions] High throughput no no
SPXN4_HUMAN [view interactions] High throughput no no
TM263_HUMAN [view interactions] High throughput no yes
LAIR2_HUMAN [view interactions] High throughput no no
PP14D_HUMAN [view interactions] High throughput no no
IFT20_HUMAN [view interactions] High throughput no yes
CD6_HUMAN [view interactions] High throughput no no
APBA1_HUMAN [view interactions] High throughput no no
CC85A_HUMAN [view interactions] High throughput no yes
PAGE1_HUMAN [view interactions] High throughput no no
TPM4_HUMAN [view entry] [view interactions] High throughput yes yes
RT18C_HUMAN [view interactions] High throughput no yes
TTHY_HUMAN [view interactions] High throughput no no
AT7L1_HUMAN [view interactions] High throughput no yes
MTPN_HUMAN [view interactions] High throughput no yes
HYPM_HUMAN [view interactions] High throughput no no
F133A_HUMAN [view interactions] High throughput no no
E41L5_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
BAP1_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
FND3A_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
OTUD1_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
RHOU_HUMAN [view interactions] High throughput no no
MON1B_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
FKB10_HUMAN [view interactions] High throughput no yes
LZTL1_HUMAN [view interactions] High throughput no no
MLP3B_HUMAN [view interactions] High throughput no yes
H31_HUMAN [view interactions] High throughput no yes
COP1_HUMAN [view interactions] High throughput no no