AKT1_HUMAN
AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis (PubMed, PubMed, PubMed, PubMed). This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates (PubMed, PubMed, PubMed, PubMed). Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported (PubMed, PubMed, PubMed, PubMed). AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface . Phosphorylation of PTPN1 at Ser-50 negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the attenuation of insulin signaling . Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for insulin-stimulated glucose transport (PubMed). AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at Ser-21 and GSK3B at Ser-9, resulting in inhibition of its kinase activity . Phosphorylation of GSK3 isoforms by AKT is also thought to be one mechanism by which cell proliferation is driven . AKT regulates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase) (PubMed). Phosphorylation of Ser-83 decreases MAP3K5 kinase activity stimulated by oxidative stress and thereby prevents apoptosis (PubMed). AKT mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at Ser-939 and Thr-1462, thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1 (PubMed). AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization (PubMed). In particular, FOXO1 is phosphorylated at Thr-24, Ser-256 and Ser-319 (PubMed). FOXO3 and FOXO4 are phosphorylated on equivalent sites (PubMed). AKT has an important role in the regulation of NF-kappa-B-dependent gene transcription and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein) (PubMed). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1 (PubMed). AKT phosphorylates Ser-454 on ATP citrate lyase (ACLY), thereby potentially regulating ACLY activity and fatty acid synthesis . Activates the 3B isoform of cyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of Ser-273, resulting in reduced cyclic AMP levels and inhibition of lipolysis . Phosphorylates PIKFYVE on Ser-318, which results in increased PI(3)P-5 activity . The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the regulation cell proliferation and cell growth. AKT plays a role as key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation . Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I) (PubMed, PubMed). AKT mediates the antiapoptotic effects of IGF-I . Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly (PubMed). May be involved in the regulation of the placental development . Phosphorylates STK4/MST1 at Thr-120 and Thr-387 leading to inhibition of its: kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3 (PubMed). Phosphorylates STK3/MST2 at Thr-117 and Thr-384 leading to inhibition of its: cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation (PubMed, PubMed). Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation (PubMed). Phosphorylates RAF1 at Ser-259 and negatively regulates its activity (PubMed). Phosphorylation of BAD stimulates its pro-apoptotic activity (PubMed). Phosphorylates KAT6A at Thr-369 and this phosphorylation inhibits the interaction of KAT6A with PML and negatively regulates its acetylation activity towards p53/TP53 (PubMed). Phosphorylates palladin (PALLD), modulating cytoskeletal organization and cell motility (PubMed). Phosphorylates prohibitin (PHB), playing an important role in cell metabolism and proliferation (PubMed). Phosphorylates CDKN1A, for which phosphorylation at Thr-145 induces its release from CDK2 and cytoplasmic relocalization (PubMed). These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation (PubMed). Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation (PubMed). Phosphorylates PCK1 at Ser-90, reducing the binding affinity of PCK1 to oxaloacetate and changing PCK1 into an atypical protein kinase activity using GTP as donor (PubMed). Also acts as an activator of TMEM175 potassium channel activity in response to growth factors: forms the lysoK(GF) complex together with TMEM175 and acts by promoting TMEM175 channel activation, independently of its protein kinase activity (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Position | Amino acid | Mutation | Disease | Overlap with binding region |
---|---|---|---|---|
17 | Glu | Lys | Breastcancer(BC) | - |
17 | Glu | Lys | Proteussyndrome(PROTEUSS) | - |
25 | Arg | Cys | Cowdensyndrome6(CWS6) | - |
435 | Thr | Pro | Cowdensyndrome6(CWS6) | - |
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001626 | DOC_AGCK_PIF_1 | DOC | 469 | 474 | - |
ELMI001976 | DOC_WW_Pin1_4 | DOC | 89 | 94 | - |
ELMI001977 | DOC_WW_Pin1_4 | DOC | 447 | 452 | - |
ELMI003847 | MOD_CK2_1 | MOD | 126 | 132 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in AKT1_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 39.8268 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 39.3939 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 38.9610 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 32.0346 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 31.6017 | 5 | yes |
GO:0005524 | ATP binding | 31.1688 | 5 | yes |
GO:0019900 | kinase binding | 30.3030 | 4 | yes |
GO:0046872 | metal ion binding | 28.5714 | 4 | no |
GO:0019901 | protein kinase binding | 27.7056 | 5 | yes |
GO:0003723 | RNA binding | 20.7792 | 4 | no |
GO:0016301 | kinase activity | 17.7489 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 17.3160 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 14.7186 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 12.5541 | 4 | yes |
GO:0106310 | protein serine kinase activity | 12.1212 | 4 | yes |
GO:0042803 | protein homodimerization activity | 10.3896 | 4 | yes |
GO:0035091 | phosphatidylinositol binding | 5.1948 | 4 | yes |
GO:1901981 | phosphatidylinositol phosphate binding | 3.8961 | 5 | yes |
GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding | 1.7316 | 4 | yes |
GO:0015459 | potassium channel regulator activity | 1.7316 | 4 | yes |
GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding | 1.2987 | 4 | yes |
GO:0099104 | potassium channel activator activity | 0.8658 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in AKT1_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 71.8615 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 67.9654 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 67.5325 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 67.5325 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 64.5022 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 62.7706 | 4 | yes |
GO:0010646 | regulation of cell communication | 58.0087 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 54.5455 | 4 | yes |
GO:0009966 | regulation of signal transduction | 53.2468 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 48.9177 | 5 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 48.9177 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 47.1861 | 5 | yes |
GO:0010468 | regulation of gene expression | 46.3203 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 46.3203 | 5 | yes |
GO:0051128 | regulation of cellular component organization | 45.8874 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 44.5887 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 44.1558 | 5 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 40.6926 | 5 | yes |
GO:0009892 | negative regulation of metabolic process | 39.8268 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 38.5281 | 5 | yes |
GO:0031399 | regulation of protein modification process | 37.6623 | 6 | yes |
GO:1902531 | regulation of intracellular signal transduction | 37.6623 | 5 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 37.2294 | 5 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 36.7965 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 36.7965 | 6 | yes |
GO:0010941 | regulation of cell death | 35.9307 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 35.0649 | 4 | no |
GO:0051049 | regulation of transport | 35.0649 | 4 | yes |
GO:0051247 | positive regulation of protein metabolic process | 34.6320 | 6 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 33.7662 | 5 | yes |
GO:0043067 | regulation of programmed cell death | 33.3333 | 5 | yes |
GO:0023056 | positive regulation of signaling | 33.3333 | 4 | no |
GO:0071310 | cellular response to organic substance | 33.3333 | 4 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 33.3333 | 5 | yes |
GO:0042981 | regulation of apoptotic process | 32.9004 | 6 | yes |
GO:0043412 | macromolecule modification | 32.9004 | 4 | yes |
GO:0006996 | organelle organization | 32.9004 | 4 | yes |
GO:0036211 | protein modification process | 32.4675 | 4 | yes |
GO:0042325 | regulation of phosphorylation | 32.4675 | 7 | yes |
GO:0010647 | positive regulation of cell communication | 32.4675 | 5 | no |
GO:0006796 | phosphate-containing compound metabolic process | 32.4675 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 30.3030 | 5 | no |
GO:0051252 | regulation of RNA metabolic process | 30.3030 | 5 | yes |
GO:0010648 | negative regulation of cell communication | 29.8701 | 5 | yes |
GO:0023057 | negative regulation of signaling | 29.8701 | 4 | yes |
GO:0022607 | cellular component assembly | 29.4372 | 4 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 29.0043 | 7 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 29.0043 | 6 | yes |
GO:0006355 | regulation of DNA-templated transcription | 29.0043 | 6 | yes |
GO:0048585 | negative regulation of response to stimulus | 29.0043 | 4 | yes |
GO:0043085 | positive regulation of catalytic activity | 28.5714 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 28.5714 | 5 | no |
GO:0042127 | regulation of cell population proliferation | 28.1385 | 4 | yes |
GO:0008104 | protein localization | 28.1385 | 4 | yes |
GO:0033043 | regulation of organelle organization | 27.7056 | 5 | yes |
GO:0001932 | regulation of protein phosphorylation | 27.7056 | 7 | yes |
GO:0060341 | regulation of cellular localization | 27.7056 | 4 | yes |
GO:0009894 | regulation of catabolic process | 27.2727 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 26.8398 | 5 | yes |
GO:0045595 | regulation of cell differentiation | 26.4069 | 4 | yes |
GO:0051338 | regulation of transferase activity | 26.4069 | 4 | yes |
GO:0009891 | positive regulation of biosynthetic process | 25.5411 | 5 | yes |
GO:0031328 | positive regulation of cellular biosynthetic process | 25.5411 | 6 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 25.1082 | 7 | yes |
GO:0010562 | positive regulation of phosphorus metabolic process | 25.1082 | 6 | yes |
GO:0060548 | negative regulation of cell death | 25.1082 | 5 | yes |
GO:0031401 | positive regulation of protein modification process | 24.6753 | 7 | yes |
GO:0032880 | regulation of protein localization | 24.6753 | 5 | yes |
GO:0051248 | negative regulation of protein metabolic process | 24.2424 | 6 | yes |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 23.8095 | 6 | yes |
GO:0010243 | response to organonitrogen compound | 23.8095 | 4 | yes |
GO:0051336 | regulation of hydrolase activity | 23.8095 | 4 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 23.3766 | 4 | yes |
GO:0043066 | negative regulation of apoptotic process | 23.3766 | 7 | yes |
GO:0043069 | negative regulation of programmed cell death | 23.3766 | 6 | yes |
GO:0042327 | positive regulation of phosphorylation | 22.9437 | 8 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 22.9437 | 4 | yes |
GO:0051726 | regulation of cell cycle | 22.9437 | 4 | yes |
GO:0080134 | regulation of response to stress | 22.9437 | 4 | yes |
GO:0051050 | positive regulation of transport | 22.5108 | 4 | yes |
GO:0016310 | phosphorylation | 22.5108 | 5 | yes |
GO:0043549 | regulation of kinase activity | 22.0779 | 5 | yes |
GO:0044087 | regulation of cellular component biogenesis | 22.0779 | 4 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.0779 | 6 | yes |
GO:0051094 | positive regulation of developmental process | 21.6450 | 4 | yes |
GO:0031329 | regulation of cellular catabolic process | 21.6450 | 5 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 21.2121 | 6 | no |
GO:2000145 | regulation of cell motility | 20.7792 | 4 | yes |
GO:0007010 | cytoskeleton organization | 20.7792 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 20.3463 | 4 | no |
GO:0030030 | cell projection organization | 20.3463 | 4 | no |
GO:0010628 | positive regulation of gene expression | 20.3463 | 6 | yes |
GO:0071702 | organic substance transport | 20.3463 | 4 | yes |
GO:0071705 | nitrogen compound transport | 19.9134 | 4 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 19.4805 | 8 | yes |
GO:0045859 | regulation of protein kinase activity | 19.4805 | 6 | yes |
GO:0008284 | positive regulation of cell population proliferation | 19.4805 | 5 | yes |
GO:0030334 | regulation of cell migration | 19.4805 | 5 | yes |
GO:2000026 | regulation of multicellular organismal development | 19.0476 | 4 | yes |
GO:0051347 | positive regulation of transferase activity | 18.6147 | 5 | yes |
GO:0031400 | negative regulation of protein modification process | 18.1818 | 7 | yes |
GO:0006357 | regulation of transcription by RNA polymerase II | 18.1818 | 7 | yes |
GO:0006468 | protein phosphorylation | 17.7489 | 5 | yes |
GO:0051129 | negative regulation of cellular component organization | 17.7489 | 5 | yes |
GO:0015031 | protein transport | 17.7489 | 4 | yes |
GO:0031344 | regulation of cell projection organization | 17.3160 | 5 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 17.3160 | 6 | yes |
GO:0030162 | regulation of proteolysis | 17.3160 | 6 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 16.8831 | 4 | yes |
GO:1903829 | positive regulation of protein localization | 16.4502 | 5 | yes |
GO:0045597 | positive regulation of cell differentiation | 16.4502 | 5 | yes |
GO:0018193 | peptidyl-amino acid modification | 16.4502 | 5 | yes |
GO:1901699 | cellular response to nitrogen compound | 16.0173 | 4 | yes |
GO:0043086 | negative regulation of catalytic activity | 16.0173 | 4 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 16.0173 | 7 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 16.0173 | 6 | yes |
GO:0033993 | response to lipid | 15.5844 | 4 | yes |
GO:0040017 | positive regulation of locomotion | 15.5844 | 4 | yes |
GO:2000147 | positive regulation of cell motility | 15.5844 | 5 | yes |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 15.5844 | 5 | yes |
GO:0051254 | positive regulation of RNA metabolic process | 15.5844 | 6 | yes |
GO:0071417 | cellular response to organonitrogen compound | 15.5844 | 4 | yes |
GO:0030335 | positive regulation of cell migration | 15.5844 | 6 | yes |
GO:0033674 | positive regulation of kinase activity | 15.1515 | 6 | yes |
GO:0051345 | positive regulation of hydrolase activity | 15.1515 | 5 | yes |
GO:0034762 | regulation of transmembrane transport | 14.7186 | 4 | yes |
GO:0080135 | regulation of cellular response to stress | 14.7186 | 4 | yes |
GO:1902680 | positive regulation of RNA biosynthetic process | 14.2857 | 7 | yes |
GO:1903508 | positive regulation of nucleic acid-templated transcription | 14.2857 | 8 | yes |
GO:0043269 | regulation of ion transport | 14.2857 | 5 | yes |
GO:2001233 | regulation of apoptotic signaling pathway | 14.2857 | 5 | yes |
GO:0045893 | positive regulation of DNA-templated transcription | 14.2857 | 7 | yes |
GO:0006886 | intracellular protein transport | 14.2857 | 4 | yes |
GO:0009896 | positive regulation of catabolic process | 14.2857 | 5 | yes |
GO:0030155 | regulation of cell adhesion | 14.2857 | 4 | yes |
GO:0006915 | apoptotic process | 13.8528 | 4 | yes |
GO:0010564 | regulation of cell cycle process | 13.8528 | 5 | yes |
GO:1902532 | negative regulation of intracellular signal transduction | 13.4199 | 6 | yes |
GO:0042326 | negative regulation of phosphorylation | 13.4199 | 8 | yes |
GO:0010629 | negative regulation of gene expression | 13.4199 | 6 | yes |
GO:0061024 | membrane organization | 13.4199 | 4 | yes |
GO:0002684 | positive regulation of immune system process | 12.9870 | 4 | yes |
GO:0045862 | positive regulation of proteolysis | 12.9870 | 7 | yes |
GO:0048878 | chemical homeostasis | 12.9870 | 4 | yes |
GO:0070848 | response to growth factor | 12.9870 | 4 | yes |
GO:0042176 | regulation of protein catabolic process | 12.5541 | 5 | yes |
GO:0045860 | positive regulation of protein kinase activity | 12.5541 | 7 | yes |
GO:0051051 | negative regulation of transport | 12.5541 | 4 | yes |
GO:0060284 | regulation of cell development | 12.5541 | 5 | yes |
GO:1901652 | response to peptide | 12.1212 | 4 | yes |
GO:0009057 | macromolecule catabolic process | 12.1212 | 4 | yes |
GO:0051052 | regulation of DNA metabolic process | 12.1212 | 5 | yes |
GO:0071363 | cellular response to growth factor stimulus | 12.1212 | 5 | yes |
GO:0001933 | negative regulation of protein phosphorylation | 11.6883 | 8 | yes |
GO:0031331 | positive regulation of cellular catabolic process | 11.2554 | 6 | yes |
GO:0010959 | regulation of metal ion transport | 11.2554 | 6 | yes |
GO:0010975 | regulation of neuron projection development | 11.2554 | 7 | yes |
GO:1901214 | regulation of neuron death | 10.8225 | 5 | yes |
GO:2000112 | regulation of cellular macromolecule biosynthetic process | 10.8225 | 6 | yes |
GO:0010506 | regulation of autophagy | 10.8225 | 6 | yes |
GO:0071396 | cellular response to lipid | 10.8225 | 5 | yes |
GO:0032870 | cellular response to hormone stimulus | 10.3896 | 4 | yes |
GO:0033365 | protein localization to organelle | 10.3896 | 5 | yes |
GO:2001234 | negative regulation of apoptotic signaling pathway | 10.3896 | 6 | yes |
GO:0045944 | positive regulation of transcription by RNA polymerase II | 10.3896 | 8 | yes |
GO:0018105 | peptidyl-serine phosphorylation | 10.3896 | 6 | yes |
GO:0018209 | peptidyl-serine modification | 10.3896 | 6 | yes |
GO:0001558 | regulation of cell growth | 9.9567 | 4 | yes |
GO:0051054 | positive regulation of DNA metabolic process | 9.9567 | 6 | yes |
GO:0051348 | negative regulation of transferase activity | 9.9567 | 5 | yes |
GO:1903320 | regulation of protein modification by small protein conjugation or removal | 9.5238 | 7 | yes |
GO:0045785 | positive regulation of cell adhesion | 9.5238 | 5 | yes |
GO:0050865 | regulation of cell activation | 9.5238 | 4 | yes |
GO:0010038 | response to metal ion | 9.5238 | 4 | yes |
GO:0071900 | regulation of protein serine/threonine kinase activity | 9.5238 | 7 | yes |
GO:1903050 | regulation of proteolysis involved in protein catabolic process | 9.0909 | 7 | yes |
GO:0034097 | response to cytokine | 9.0909 | 4 | yes |
GO:0034248 | regulation of cellular amide metabolic process | 9.0909 | 5 | yes |
GO:0036293 | response to decreased oxygen levels | 9.0909 | 4 | yes |
GO:0043393 | regulation of protein binding | 9.0909 | 4 | yes |
GO:0043434 | response to peptide hormone | 9.0909 | 4 | yes |
GO:0050678 | regulation of epithelial cell proliferation | 9.0909 | 5 | yes |
GO:1901653 | cellular response to peptide | 8.6580 | 5 | yes |
GO:0002694 | regulation of leukocyte activation | 8.6580 | 4 | yes |
GO:0006109 | regulation of carbohydrate metabolic process | 8.6580 | 5 | yes |
GO:0007346 | regulation of mitotic cell cycle | 8.6580 | 5 | yes |
GO:0010608 | post-transcriptional regulation of gene expression | 8.6580 | 6 | yes |
GO:0010639 | negative regulation of organelle organization | 8.6580 | 6 | yes |
GO:0051960 | regulation of nervous system development | 8.6580 | 5 | yes |
GO:0052547 | regulation of peptidase activity | 8.6580 | 5 | yes |
GO:0052548 | regulation of endopeptidase activity | 8.6580 | 6 | yes |
GO:0031396 | regulation of protein ubiquitination | 8.2251 | 8 | yes |
GO:1900180 | regulation of protein localization to nucleus | 8.2251 | 6 | yes |
GO:0033673 | negative regulation of kinase activity | 8.2251 | 6 | yes |
GO:0034764 | positive regulation of transmembrane transport | 8.2251 | 5 | yes |
GO:0043467 | regulation of generation of precursor metabolites and energy | 8.2251 | 5 | yes |
GO:0006417 | regulation of translation | 8.2251 | 6 | yes |
GO:0009895 | negative regulation of catabolic process | 8.2251 | 5 | yes |
GO:0051346 | negative regulation of hydrolase activity | 8.2251 | 5 | yes |
GO:0010632 | regulation of epithelial cell migration | 8.2251 | 4 | yes |
GO:0062012 | regulation of small molecule metabolic process | 8.2251 | 4 | yes |
GO:0019216 | regulation of lipid metabolic process | 8.2251 | 5 | yes |
GO:1901565 | organonitrogen compound catabolic process | 7.7922 | 4 | yes |
GO:2000116 | regulation of cysteine-type endopeptidase activity | 7.7922 | 7 | yes |
GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 7.7922 | 6 | yes |
GO:0044271 | cellular nitrogen compound biosynthetic process | 7.7922 | 4 | yes |
GO:0045787 | positive regulation of cell cycle | 7.7922 | 5 | yes |
GO:0006469 | negative regulation of protein kinase activity | 7.7922 | 7 | yes |
GO:0046777 | protein autophosphorylation | 7.7922 | 6 | yes |
GO:0051249 | regulation of lymphocyte activation | 7.7922 | 5 | yes |
GO:0071345 | cellular response to cytokine stimulus | 7.7922 | 5 | yes |
GO:0097305 | response to alcohol | 7.3593 | 4 | yes |
GO:0031667 | response to nutrient levels | 7.3593 | 4 | yes |
GO:1901215 | negative regulation of neuron death | 7.3593 | 6 | yes |
GO:0032868 | response to insulin | 7.3593 | 5 | yes |
GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 7.3593 | 6 | yes |
GO:0043270 | positive regulation of ion transport | 7.3593 | 5 | yes |
GO:0045732 | positive regulation of protein catabolic process | 7.3593 | 6 | yes |
GO:0009059 | macromolecule biosynthetic process | 7.3593 | 4 | yes |
GO:0010675 | regulation of cellular carbohydrate metabolic process | 7.3593 | 5 | yes |
GO:0070647 | protein modification by small protein conjugation or removal | 7.3593 | 5 | yes |
GO:0030163 | protein catabolic process | 7.3593 | 4 | yes |
GO:1905475 | regulation of protein localization to membrane | 6.9264 | 6 | yes |
GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 6.9264 | 8 | yes |
GO:0007005 | mitochondrion organization | 6.9264 | 5 | yes |
GO:0050863 | regulation of T cell activation | 6.9264 | 6 | yes |
GO:0051091 | positive regulation of DNA-binding transcription factor activity | 6.9264 | 4 | yes |
GO:0061136 | regulation of proteasomal protein catabolic process | 6.9264 | 6 | yes |
GO:0016241 | regulation of macroautophagy | 6.9264 | 7 | yes |
GO:1901654 | response to ketone | 6.4935 | 4 | yes |
GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 6.4935 | 8 | yes |
GO:0048660 | regulation of smooth muscle cell proliferation | 6.4935 | 5 | yes |
GO:0050679 | positive regulation of epithelial cell proliferation | 6.4935 | 6 | yes |
GO:0050867 | positive regulation of cell activation | 6.4935 | 5 | yes |
GO:0009416 | response to light stimulus | 6.4935 | 4 | yes |
GO:0022407 | regulation of cell-cell adhesion | 6.4935 | 5 | yes |
GO:0071902 | positive regulation of protein serine/threonine kinase activity | 6.4935 | 8 | yes |
GO:0072594 | establishment of protein localization to organelle | 6.4935 | 4 | yes |
GO:0031330 | negative regulation of cellular catabolic process | 6.0606 | 6 | yes |
GO:1900182 | positive regulation of protein localization to nucleus | 6.0606 | 6 | yes |
GO:0032446 | protein modification by small protein conjugation | 6.0606 | 6 | yes |
GO:0033500 | carbohydrate homeostasis | 6.0606 | 5 | yes |
GO:1904375 | regulation of protein localization to cell periphery | 6.0606 | 6 | yes |
GO:0042593 | glucose homeostasis | 6.0606 | 6 | yes |
GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 6.0606 | 6 | yes |
GO:0006954 | inflammatory response | 6.0606 | 4 | yes |
GO:0048638 | regulation of developmental growth | 6.0606 | 4 | yes |
GO:0010634 | positive regulation of epithelial cell migration | 6.0606 | 5 | yes |
GO:0010821 | regulation of mitochondrion organization | 6.0606 | 6 | yes |
GO:0062013 | positive regulation of small molecule metabolic process | 6.0606 | 5 | yes |
GO:0016567 | protein ubiquitination | 6.0606 | 7 | yes |
GO:0018107 | peptidyl-threonine phosphorylation | 6.0606 | 6 | yes |
GO:0018210 | peptidyl-threonine modification | 6.0606 | 6 | yes |
GO:0019318 | hexose metabolic process | 6.0606 | 4 | yes |
GO:0033135 | regulation of peptidyl-serine phosphorylation | 5.6277 | 8 | yes |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 5.6277 | 6 | yes |
GO:1903321 | negative regulation of protein modification by small protein conjugation or removal | 5.6277 | 8 | yes |
GO:0034763 | negative regulation of transmembrane transport | 5.6277 | 5 | yes |
GO:0036294 | cellular response to decreased oxygen levels | 5.6277 | 5 | yes |
GO:0038127 | ERBB signaling pathway | 5.6277 | 6 | yes |
GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 5.6277 | 7 | yes |
GO:0043255 | regulation of carbohydrate biosynthetic process | 5.6277 | 5 | yes |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 5.6277 | 7 | yes |
GO:0001667 | ameboidal-type cell migration | 5.6277 | 4 | yes |
GO:0045834 | positive regulation of lipid metabolic process | 5.6277 | 5 | yes |
GO:0045861 | negative regulation of proteolysis | 5.6277 | 7 | yes |
GO:0002696 | positive regulation of leukocyte activation | 5.6277 | 5 | yes |
GO:0045927 | positive regulation of growth | 5.6277 | 4 | yes |
GO:0006006 | glucose metabolic process | 5.6277 | 5 | yes |
GO:0007162 | negative regulation of cell adhesion | 5.6277 | 5 | yes |
GO:0051100 | negative regulation of binding | 5.6277 | 4 | yes |
GO:0051251 | positive regulation of lymphocyte activation | 5.6277 | 6 | yes |
GO:0071375 | cellular response to peptide hormone stimulus | 5.6277 | 5 | yes |
GO:0071453 | cellular response to oxygen levels | 5.6277 | 4 | yes |
GO:0090068 | positive regulation of cell cycle process | 5.1948 | 6 | yes |
GO:0031397 | negative regulation of protein ubiquitination | 5.1948 | 9 | yes |
GO:0032091 | negative regulation of protein binding | 5.1948 | 5 | yes |
GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 5.1948 | 7 | yes |
GO:1901800 | positive regulation of proteasomal protein catabolic process | 5.1948 | 7 | yes |
GO:1901987 | regulation of cell cycle phase transition | 5.1948 | 6 | yes |
GO:0032869 | cellular response to insulin stimulus | 5.1948 | 6 | yes |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 5.1948 | 9 | yes |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 5.1948 | 7 | yes |
GO:0034504 | protein localization to nucleus | 5.1948 | 6 | yes |
GO:1905477 | positive regulation of protein localization to membrane | 5.1948 | 6 | yes |
GO:0040013 | negative regulation of locomotion | 5.1948 | 4 | yes |
GO:2000146 | negative regulation of cell motility | 5.1948 | 5 | yes |
GO:0000302 | response to reactive oxygen species | 5.1948 | 4 | yes |
GO:0002683 | negative regulation of immune system process | 5.1948 | 4 | yes |
GO:0006913 | nucleocytoplasmic transport | 5.1948 | 5 | yes |
GO:0008286 | insulin receptor signaling pathway | 5.1948 | 6 | yes |
GO:0050870 | positive regulation of T cell activation | 5.1948 | 7 | yes |
GO:0051169 | nuclear transport | 5.1948 | 4 | yes |
GO:0010594 | regulation of endothelial cell migration | 5.1948 | 5 | yes |
GO:0062197 | cellular response to chemical stress | 5.1948 | 4 | yes |
GO:0015980 | energy derivation by oxidation of organic compounds | 5.1948 | 4 | yes |
GO:0071241 | cellular response to inorganic substance | 5.1948 | 4 | yes |
GO:0022409 | positive regulation of cell-cell adhesion | 5.1948 | 6 | yes |
GO:1901655 | cellular response to ketone | 4.7619 | 5 | yes |
GO:1903076 | regulation of protein localization to plasma membrane | 4.7619 | 7 | yes |
GO:0034599 | cellular response to oxidative stress | 4.7619 | 4 | yes |
GO:0048015 | phosphatidylinositol-mediated signaling | 4.7619 | 5 | yes |
GO:0048017 | inositol lipid-mediated signaling | 4.7619 | 4 | yes |
GO:0007173 | epidermal growth factor receptor signaling pathway | 4.7619 | 7 | yes |
GO:0010827 | regulation of glucose transmembrane transport | 4.7619 | 5 | yes |
GO:0030307 | positive regulation of cell growth | 4.7619 | 5 | yes |
GO:0030336 | negative regulation of cell migration | 4.7619 | 6 | yes |
GO:0097306 | cellular response to alcohol | 4.3290 | 5 | yes |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 4.3290 | 8 | yes |
GO:1901990 | regulation of mitotic cell cycle phase transition | 4.3290 | 6 | yes |
GO:0032881 | regulation of polysaccharide metabolic process | 4.3290 | 5 | yes |
GO:0032885 | regulation of polysaccharide biosynthetic process | 4.3290 | 6 | yes |
GO:0034645 | cellular macromolecule biosynthetic process | 4.3290 | 4 | yes |
GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 4.3290 | 7 | yes |
GO:0001936 | regulation of endothelial cell proliferation | 4.3290 | 6 | yes |
GO:0002685 | regulation of leukocyte migration | 4.3290 | 4 | yes |
GO:0045913 | positive regulation of carbohydrate metabolic process | 4.3290 | 5 | yes |
GO:0048661 | positive regulation of smooth muscle cell proliferation | 4.3290 | 6 | yes |
GO:0010466 | negative regulation of peptidase activity | 4.3290 | 6 | yes |
GO:0051881 | regulation of mitochondrial membrane potential | 4.3290 | 4 | yes |
GO:0010951 | negative regulation of endopeptidase activity | 4.3290 | 7 | yes |
GO:0071248 | cellular response to metal ion | 4.3290 | 5 | yes |
GO:0019221 | cytokine-mediated signaling pathway | 4.3290 | 4 | yes |
GO:0080164 | regulation of nitric oxide metabolic process | 3.8961 | 5 | yes |
GO:1900407 | regulation of cellular response to oxidative stress | 3.8961 | 5 | yes |
GO:1902882 | regulation of response to oxidative stress | 3.8961 | 5 | yes |
GO:1903201 | regulation of oxidative stress-induced cell death | 3.8961 | 5 | yes |
GO:1904377 | positive regulation of protein localization to cell periphery | 3.8961 | 6 | yes |
GO:1990090 | cellular response to nerve growth factor stimulus | 3.8961 | 4 | yes |
GO:2000117 | negative regulation of cysteine-type endopeptidase activity | 3.8961 | 8 | yes |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 3.8961 | 8 | yes |
GO:0045428 | regulation of nitric oxide biosynthetic process | 3.8961 | 6 | yes |
GO:0001938 | positive regulation of endothelial cell proliferation | 3.8961 | 7 | yes |
GO:0005979 | regulation of glycogen biosynthetic process | 3.8961 | 7 | yes |
GO:0006112 | energy reserve metabolic process | 3.8961 | 5 | yes |
GO:0046324 | regulation of glucose import | 3.8961 | 6 | yes |
GO:0006606 | protein import into nucleus | 3.8961 | 5 | yes |
GO:0051170 | import into nucleus | 3.8961 | 6 | yes |
GO:0010631 | epithelial cell migration | 3.8961 | 5 | yes |
GO:0010823 | negative regulation of mitochondrion organization | 3.8961 | 7 | yes |
GO:0010962 | regulation of glucan biosynthetic process | 3.8961 | 6 | yes |
GO:0014065 | phosphatidylinositol 3-kinase signaling | 3.8961 | 6 | yes |
GO:0070873 | regulation of glycogen metabolic process | 3.8961 | 6 | yes |
GO:0071364 | cellular response to epidermal growth factor stimulus | 3.8961 | 4 | yes |
GO:1902806 | regulation of cell cycle G1/S phase transition | 3.4632 | 7 | yes |
GO:1903078 | positive regulation of protein localization to plasma membrane | 3.4632 | 7 | yes |
GO:1903202 | negative regulation of oxidative stress-induced cell death | 3.4632 | 6 | yes |
GO:1903311 | regulation of mRNA metabolic process | 3.4632 | 6 | yes |
GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 3.4632 | 7 | yes |
GO:0043535 | regulation of blood vessel endothelial cell migration | 3.4632 | 6 | yes |
GO:0044042 | glucan metabolic process | 3.4632 | 5 | yes |
GO:0044264 | cellular polysaccharide metabolic process | 3.4632 | 4 | yes |
GO:0001649 | osteoblast differentiation | 3.4632 | 4 | yes |
GO:0002028 | regulation of sodium ion transport | 3.4632 | 7 | yes |
GO:0005976 | polysaccharide metabolic process | 3.4632 | 4 | yes |
GO:0005977 | glycogen metabolic process | 3.4632 | 6 | yes |
GO:0045931 | positive regulation of mitotic cell cycle | 3.4632 | 6 | yes |
GO:0006073 | cellular glucan metabolic process | 3.4632 | 5 | yes |
GO:0010507 | negative regulation of autophagy | 3.4632 | 7 | yes |
GO:0010595 | positive regulation of endothelial cell migration | 3.4632 | 6 | yes |
GO:0010676 | positive regulation of cellular carbohydrate metabolic process | 3.4632 | 6 | yes |
GO:0060078 | regulation of postsynaptic membrane potential | 3.4632 | 4 | yes |
GO:0010828 | positive regulation of glucose transmembrane transport | 3.4632 | 6 | yes |
GO:0010906 | regulation of glucose metabolic process | 3.4632 | 5 | yes |
GO:0030855 | epithelial cell differentiation | 3.4632 | 4 | yes |
GO:0031929 | TOR signaling | 3.0303 | 4 | yes |
GO:0032368 | regulation of lipid transport | 3.0303 | 5 | yes |
GO:1901796 | regulation of signal transduction by p53 class mediator | 3.0303 | 6 | yes |
GO:0034612 | response to tumor necrosis factor | 3.0303 | 5 | yes |
GO:0034614 | cellular response to reactive oxygen species | 3.0303 | 5 | yes |
GO:1904029 | regulation of cyclin-dependent protein kinase activity | 3.0303 | 5 | yes |
GO:1904407 | positive regulation of nitric oxide metabolic process | 3.0303 | 6 | yes |
GO:1905952 | regulation of lipid localization | 3.0303 | 4 | yes |
GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 3.0303 | 7 | yes |
GO:0043491 | protein kinase B signaling | 3.0303 | 4 | yes |
GO:0043542 | endothelial cell migration | 3.0303 | 6 | yes |
GO:0045429 | positive regulation of nitric oxide biosynthetic process | 3.0303 | 7 | yes |
GO:0046326 | positive regulation of glucose import | 3.0303 | 7 | yes |
GO:0048009 | insulin-like growth factor receptor signaling pathway | 3.0303 | 6 | yes |
GO:0007009 | plasma membrane organization | 3.0303 | 5 | yes |
GO:0048639 | positive regulation of developmental growth | 3.0303 | 5 | yes |
GO:0051341 | regulation of oxidoreductase activity | 3.0303 | 4 | yes |
GO:0060079 | excitatory postsynaptic potential | 3.0303 | 5 | yes |
GO:0010762 | regulation of fibroblast migration | 3.0303 | 6 | yes |
GO:0071675 | regulation of mononuclear cell migration | 3.0303 | 5 | yes |
GO:0071901 | negative regulation of protein serine/threonine kinase activity | 3.0303 | 8 | yes |
GO:0090199 | regulation of release of cytochrome c from mitochondria | 2.5974 | 7 | yes |
GO:0031641 | regulation of myelination | 2.5974 | 4 | yes |
GO:0042692 | muscle cell differentiation | 2.5974 | 4 | yes |
GO:0043536 | positive regulation of blood vessel endothelial cell migration | 2.5974 | 7 | yes |
GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 2.5974 | 6 | yes |
GO:0046686 | response to cadmium ion | 2.5974 | 5 | yes |
GO:0008637 | apoptotic mitochondrial changes | 2.5974 | 6 | yes |
GO:0010565 | regulation of cellular ketone metabolic process | 2.5974 | 5 | yes |
GO:0051353 | positive regulation of oxidoreductase activity | 2.5974 | 5 | yes |
GO:0010907 | positive regulation of glucose metabolic process | 2.5974 | 6 | yes |
GO:0070585 | protein localization to mitochondrion | 2.5974 | 6 | yes |
GO:0016242 | negative regulation of macroautophagy | 2.5974 | 8 | yes |
GO:0071356 | cellular response to tumor necrosis factor | 2.5974 | 6 | yes |
GO:0072655 | establishment of protein localization to mitochondrion | 2.5974 | 5 | yes |
GO:0090201 | negative regulation of release of cytochrome c from mitochondria | 2.1645 | 7 | yes |
GO:0031663 | lipopolysaccharide-mediated signaling pathway | 2.1645 | 4 | yes |
GO:1901099 | negative regulation of signal transduction in absence of ligand | 2.1645 | 6 | yes |
GO:0032369 | negative regulation of lipid transport | 2.1645 | 5 | yes |
GO:1901989 | positive regulation of cell cycle phase transition | 2.1645 | 7 | yes |
GO:1902175 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | 2.1645 | 6 | yes |
GO:1902176 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | 2.1645 | 7 | yes |
GO:0032890 | regulation of organic acid transport | 2.1645 | 5 | yes |
GO:0035924 | cellular response to vascular endothelial growth factor stimulus | 2.1645 | 6 | yes |
GO:1905953 | negative regulation of lipid localization | 2.1645 | 4 | yes |
GO:2000008 | regulation of protein localization to cell surface | 2.1645 | 6 | yes |
GO:2000074 | regulation of type B pancreatic cell development | 2.1645 | 6 | yes |
GO:0043276 | anoikis | 2.1645 | 5 | yes |
GO:0043488 | regulation of mRNA stability | 2.1645 | 4 | yes |
GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | 2.1645 | 7 | yes |
GO:0045725 | positive regulation of glycogen biosynthetic process | 2.1645 | 7 | yes |
GO:0045838 | positive regulation of membrane potential | 2.1645 | 4 | yes |
GO:0046890 | regulation of lipid biosynthetic process | 2.1645 | 5 | yes |
GO:0048568 | embryonic organ development | 2.1645 | 4 | yes |
GO:0008593 | regulation of Notch signaling pathway | 2.1645 | 5 | yes |
GO:0050994 | regulation of lipid catabolic process | 2.1645 | 5 | yes |
GO:0009411 | response to UV | 2.1645 | 5 | yes |
GO:0051146 | striated muscle cell differentiation | 2.1645 | 5 | yes |
GO:0010763 | positive regulation of fibroblast migration | 2.1645 | 7 | yes |
GO:0061013 | regulation of mRNA catabolic process | 2.1645 | 6 | yes |
GO:0010918 | positive regulation of mitochondrial membrane potential | 2.1645 | 5 | yes |
GO:0062014 | negative regulation of small molecule metabolic process | 2.1645 | 5 | yes |
GO:0070875 | positive regulation of glycogen metabolic process | 2.1645 | 6 | yes |
GO:0019217 | regulation of fatty acid metabolic process | 2.1645 | 6 | yes |
GO:0022408 | negative regulation of cell-cell adhesion | 2.1645 | 6 | yes |
GO:0031998 | regulation of fatty acid beta-oxidation | 1.7316 | 6 | yes |
GO:0032069 | regulation of nuclease activity | 1.7316 | 5 | yes |
GO:0032768 | regulation of monooxygenase activity | 1.7316 | 5 | yes |
GO:1901992 | positive regulation of mitotic cell cycle phase transition | 1.7316 | 7 | yes |
GO:0034694 | response to prostaglandin | 1.7316 | 4 | yes |
GO:0034695 | response to prostaglandin E | 1.7316 | 5 | yes |
GO:1904031 | positive regulation of cyclin-dependent protein kinase activity | 1.7316 | 6 | yes |
GO:0043217 | myelin maintenance | 1.7316 | 6 | yes |
GO:2000401 | regulation of lymphocyte migration | 1.7316 | 6 | yes |
GO:0043534 | blood vessel endothelial cell migration | 1.7316 | 7 | yes |
GO:0045833 | negative regulation of lipid metabolic process | 1.7316 | 5 | yes |
GO:0046320 | regulation of fatty acid oxidation | 1.7316 | 7 | yes |
GO:0046620 | regulation of organ growth | 1.7316 | 4 | yes |
GO:0046889 | positive regulation of lipid biosynthetic process | 1.7316 | 6 | yes |
GO:0008643 | carbohydrate transport | 1.7316 | 5 | yes |
GO:0010467 | gene expression | 1.7316 | 4 | yes |
GO:0070227 | lymphocyte apoptotic process | 1.7316 | 6 | yes |
GO:0016051 | carbohydrate biosynthetic process | 1.7316 | 4 | yes |
GO:0071276 | cellular response to cadmium ion | 1.7316 | 6 | yes |
GO:0071379 | cellular response to prostaglandin stimulus | 1.7316 | 5 | yes |
GO:0071380 | cellular response to prostaglandin E stimulus | 1.7316 | 6 | yes |
GO:0071887 | leukocyte apoptotic process | 1.7316 | 5 | yes |
GO:0072595 | maintenance of protein localization in organelle | 1.7316 | 4 | yes |
GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus | 1.2987 | 6 | yes |
GO:0097012 | response to granulocyte macrophage colony-stimulating factor | 1.2987 | 5 | yes |
GO:0140212 | regulation of long-chain fatty acid import into cell | 1.2987 | 7 | yes |
GO:0140213 | negative regulation of long-chain fatty acid import into cell | 1.2987 | 7 | yes |
GO:0032070 | regulation of deoxyribonuclease activity | 1.2987 | 6 | yes |
GO:0032071 | regulation of endodeoxyribonuclease activity | 1.2987 | 7 | yes |
GO:0032075 | positive regulation of nuclease activity | 1.2987 | 6 | yes |
GO:0032287 | peripheral nervous system myelin maintenance | 1.2987 | 7 | yes |
GO:0032770 | positive regulation of monooxygenase activity | 1.2987 | 6 | yes |
GO:0032891 | negative regulation of organic acid transport | 1.2987 | 5 | yes |
GO:1902808 | positive regulation of cell cycle G1/S phase transition | 1.2987 | 8 | yes |
GO:1903038 | negative regulation of leukocyte cell-cell adhesion | 1.2987 | 7 | yes |
GO:0033692 | cellular polysaccharide biosynthetic process | 1.2987 | 5 | yes |
GO:0034637 | cellular carbohydrate biosynthetic process | 1.2987 | 4 | yes |
GO:1903719 | regulation of I-kappaB phosphorylation | 1.2987 | 8 | yes |
GO:2000010 | positive regulation of protein localization to cell surface | 1.2987 | 6 | yes |
GO:2000191 | regulation of fatty acid transport | 1.2987 | 6 | yes |
GO:2000192 | negative regulation of fatty acid transport | 1.2987 | 6 | yes |
GO:0000271 | polysaccharide biosynthetic process | 1.2987 | 5 | yes |
GO:0045598 | regulation of fat cell differentiation | 1.2987 | 5 | yes |
GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity | 1.2987 | 6 | yes |
GO:0045746 | negative regulation of Notch signaling pathway | 1.2987 | 6 | yes |
GO:0002042 | cell migration involved in sprouting angiogenesis | 1.2987 | 8 | yes |
GO:0003376 | sphingosine-1-phosphate receptor signaling pathway | 1.2987 | 4 | yes |
GO:0005978 | glycogen biosynthetic process | 1.2987 | 7 | yes |
GO:0046209 | nitric oxide metabolic process | 1.2987 | 4 | yes |
GO:0046622 | positive regulation of organ growth | 1.2987 | 5 | yes |
GO:0006809 | nitric oxide biosynthetic process | 1.2987 | 5 | yes |
GO:0006924 | activation-induced cell death of T cells | 1.2987 | 8 | yes |
GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 1.2987 | 4 | yes |
GO:0009250 | glucan biosynthetic process | 1.2987 | 6 | yes |
GO:0050999 | regulation of nitric-oxide synthase activity | 1.2987 | 6 | yes |
GO:0051000 | positive regulation of nitric-oxide synthase activity | 1.2987 | 7 | yes |
GO:0010746 | regulation of long-chain fatty acid import across plasma membrane | 1.2987 | 5 | yes |
GO:0010748 | negative regulation of long-chain fatty acid import across plasma membrane | 1.2987 | 6 | yes |
GO:0010761 | fibroblast migration | 1.2987 | 5 | yes |
GO:0010765 | positive regulation of sodium ion transport | 1.2987 | 6 | yes |
GO:0060644 | mammary gland epithelial cell differentiation | 1.2987 | 5 | yes |
GO:0060674 | placenta blood vessel development | 1.2987 | 4 | yes |
GO:0060716 | labyrinthine layer blood vessel development | 1.2987 | 5 | yes |
GO:0070231 | T cell apoptotic process | 1.2987 | 7 | yes |
GO:0072656 | maintenance of protein location in mitochondrion | 1.2987 | 5 | yes |
GO:0100002 | negative regulation of protein kinase activity by protein phosphorylation | 0.8658 | 6 | yes |
GO:0140052 | cellular response to oxidised low-density lipoprotein particle stimulus | 0.8658 | 4 | yes |
GO:0031999 | negative regulation of fatty acid beta-oxidation | 0.8658 | 7 | yes |
GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle | 0.8658 | 8 | yes |
GO:0032077 | positive regulation of deoxyribonuclease activity | 0.8658 | 7 | yes |
GO:0032079 | positive regulation of endodeoxyribonuclease activity | 0.8658 | 8 | yes |
GO:1903721 | positive regulation of I-kappaB phosphorylation | 0.8658 | 9 | yes |
GO:0035655 | interleukin-18-mediated signaling pathway | 0.8658 | 5 | yes |
GO:0038061 | NIK/NF-kappaB signaling | 0.8658 | 4 | yes |
GO:1990418 | response to insulin-like growth factor stimulus | 0.8658 | 4 | yes |
GO:2000402 | negative regulation of lymphocyte migration | 0.8658 | 7 | yes |
GO:0045600 | positive regulation of fat cell differentiation | 0.8658 | 6 | yes |
GO:0002686 | negative regulation of leukocyte migration | 0.8658 | 5 | yes |
GO:0045922 | negative regulation of fatty acid metabolic process | 0.8658 | 6 | yes |
GO:0046322 | negative regulation of fatty acid oxidation | 0.8658 | 7 | yes |
GO:0050995 | negative regulation of lipid catabolic process | 0.8658 | 6 | yes |
GO:0060416 | response to growth hormone | 0.8658 | 5 | yes |
GO:0060709 | glycogen cell differentiation involved in embryonic placenta development | 0.8658 | 4 | yes |
GO:0070141 | response to UV-A | 0.8658 | 6 | yes |
GO:0071676 | negative regulation of mononuclear cell migration | 0.8658 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in AKT1_HUMAN |
---|---|---|---|---|
DOID:331 | central nervous system disease | 3.4632 | 3 | no |
DOID:0050686 | organ system cancer | 2.1645 | 3 | yes |
DOID:612 | primary immunodeficiency disease | 2.1645 | 3 | no |
DOID:1289 | neurodegenerative disease | 2.1645 | 4 | no |
DOID:0050700 | cardiomyopathy | 1.7316 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 1.7316 | 5 | no |
DOID:114 | heart disease | 1.7316 | 3 | no |
DOID:231 | motor neuron disease | 1.7316 | 5 | no |
DOID:6457 | Cowden syndrome | 1.2987 | 3 | yes |
DOID:332 | amyotrophic lateral sclerosis | 1.2987 | 6 | no |
DOID:0111962 | combined immunodeficiency | 1.2987 | 4 | no |
DOID:936 | brain disease | 1.2987 | 4 | no |
DOID:0081002 | Cowden syndrome 6 | 0.8658 | 4 | yes |
DOID:13482 | Proteus syndrome | 0.8658 | 3 | yes |
DOID:1612 | breast cancer | 0.8658 | 5 | yes |
DOID:5093 | thoracic cancer | 0.8658 | 4 | yes |
DOID:10780 | primary polycythemia | 0.8658 | 5 | no |
DOID:4961 | bone marrow disease | 0.8658 | 3 | no |
DOID:8432 | polycythemia | 0.8658 | 4 | no |
DOID:2843 | long QT syndrome | 0.8658 | 6 | no |
DOID:0111198 | autosomal dominant distal hereditary motor neuronopathy | 0.8658 | 7 | no |
DOID:12377 | spinal muscular atrophy | 0.8658 | 6 | no |
DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 0.8658 | 7 | no |
DOID:10595 | Charcot-Marie-Tooth disease | 0.8658 | 6 | no |
DOID:440 | neuromuscular disease | 0.8658 | 5 | no |
DOID:574 | peripheral nervous system disease | 0.8658 | 3 | no |
DOID:870 | neuropathy | 0.8658 | 4 | no |
DOID:37 | skin disease | 0.8658 | 3 | no |
DOID:120 | female reproductive organ cancer | 0.8658 | 5 | no |
DOID:193 | reproductive organ cancer | 0.8658 | 4 | no |
DOID:627 | severe combined immunodeficiency | 0.8658 | 5 | no |
DOID:0050155 | sensory system disease | 0.8658 | 3 | no |
DOID:0050563 | nonsyndromic deafness | 0.8658 | 5 | no |
DOID:0050564 | autosomal dominant nonsyndromic deafness | 0.8658 | 6 | no |
DOID:2742 | auditory system disease | 0.8658 | 4 | no |
DOID:0081062 | diabetes | 0.8658 | 5 | no |
DOID:2978 | carbohydrate metabolic disorder | 0.8658 | 3 | no |
DOID:4194 | glucose metabolism disease | 0.8658 | 4 | no |
DOID:9351 | diabetes mellitus | 0.8658 | 6 | no |
DOID:9352 | type 2 diabetes mellitus | 0.8658 | 7 | no |
DOID:12930 | dilated cardiomyopathy | 0.8658 | 6 | no |
DOID:0080000 | muscular disease | 0.8658 | 3 | no |
DOID:423 | myopathy | 0.8658 | 5 | no |
DOID:66 | muscle tissue disease | 0.8658 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
WNK4_HUMAN | [view interactions] | Low throughput | no | yes |
RNF11_HUMAN | [view interactions] | Low throughput | no | yes |
RN115_HUMAN | [view interactions] | Low throughput | no | yes |
PTPA_HUMAN | [view interactions] | Low throughput | no | yes |
F261_HUMAN | [view interactions] | Low throughput | no | no |
H2B2F_HUMAN | [view interactions] | Low throughput | no | yes |
H2B2E_HUMAN | [view interactions] | Low throughput | no | yes |
HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
H2B1K_HUMAN | [view interactions] | Low throughput | no | yes |
H2B1C_HUMAN | [view interactions] | Low throughput | no | yes |
H2B1H_HUMAN | [view interactions] | Low throughput | no | yes |
H2B1D_HUMAN | [view interactions] | Low throughput | no | yes |
CASP3_HUMAN | [view interactions] | Low throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BAX_HUMAN | [view interactions] | Low throughput | no | yes |
CREB1_HUMAN | [view interactions] | Low throughput | no | yes |
NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
RON_HUMAN | [view interactions] | Low throughput | no | yes |
MAPK2_HUMAN | [view interactions] | Low throughput | no | yes |
TBCD4_HUMAN | [view interactions] | Low throughput | no | yes |
CTND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ITPR3_HUMAN | [view interactions] | Low throughput | no | yes |
NOS3_HUMAN | [view interactions] | Low throughput | no | no |
CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
GATA2_HUMAN | [view interactions] | Low throughput | no | yes |
CDN1A_HUMAN | [view interactions] | Low throughput | no | no |
TRMB_HUMAN | [view interactions] | Low throughput | no | yes |
BAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GATA1_HUMAN | [view interactions] | Low throughput | no | no |
PIAS2_HUMAN | [view interactions] | Low throughput | no | yes |
SH2B2_HUMAN | [view interactions] | Low throughput | no | no |
IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
KAT6A_HUMAN | [view interactions] | Low throughput | no | yes |
IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
RHG07_HUMAN | [view interactions] | Low throughput | no | no |
BRAF_HUMAN | [view interactions] | Low throughput | no | yes |
MK08_HUMAN | [view interactions] | Low throughput | no | yes |
MK14_HUMAN | [view interactions] | Low throughput | no | yes |
MK09_HUMAN | [view interactions] | Low throughput | no | yes |
PAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KLHL3_HUMAN | [view interactions] | Low throughput | no | no |
EF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
H2B1B_HUMAN | [view interactions] | Low throughput | no | yes |
PLXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KC1D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ARFP2_HUMAN | [view interactions] | Low throughput | no | no |
BCL3_HUMAN | [view interactions] | Low throughput | no | yes |
FANCA_HUMAN | [view interactions] | Low throughput | no | no |
ITB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IMDH2_HUMAN | [view interactions] | Low throughput | no | yes |
RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
K1C10_HUMAN | [view interactions] | Low throughput | no | no |
ZRAN1_HUMAN | [view interactions] | Low throughput | no | yes |
UXS1_HUMAN | [view interactions] | Low throughput | no | yes |
KANK1_HUMAN | [view interactions] | Low throughput | no | yes |
PIAS1_HUMAN | [view interactions] | Low throughput | no | yes |
SP1_HUMAN | [view interactions] | Low throughput | no | yes |
PHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SP3_HUMAN | [view interactions] | Low throughput | no | no |
GRDN_HUMAN | [view interactions] | Low throughput | no | no |
SSH1_HUMAN | [view interactions] | Low throughput | no | yes |
FBX31_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PI51C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BABA1_HUMAN | [view interactions] | Low throughput | no | yes |
EMSY_HUMAN | [view interactions] | Low throughput | no | yes |
NOTC1_HUMAN | [view interactions] | Low throughput | no | yes |
BEX1_HUMAN | [view interactions] | Low throughput | no | yes |
UBP11_HUMAN | [view interactions] | Low throughput | no | yes |
OTUB2_HUMAN | [view interactions] | Low throughput | no | no |
OTUD5_HUMAN | [view interactions] | Low throughput | no | yes |
ANDR_HUMAN | [view interactions] | Low throughput | no | no |
OTU6A_HUMAN | [view interactions] | Low throughput | no | no |
AKTIP_HUMAN | [view interactions] | Low throughput | no | yes |
CAST1_HUMAN | [view interactions] | Low throughput | no | yes |
IRAK1_HUMAN | [view interactions] | Low throughput | no | yes |
UBP10_HUMAN | [view interactions] | Low throughput | no | yes |
MTCP1_HUMAN | [view interactions] | Low throughput | no | no |
NCF2_HUMAN | [view interactions] | Low throughput | no | no |
TSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TSC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCT_HUMAN | [view interactions] | Low throughput | no | no |
NR4A1_HUMAN | [view interactions] | Low throughput | no | yes |
M3K11_HUMAN | [view interactions] | Low throughput | no | yes |
MP2K4_HUMAN | [view interactions] | Low throughput | no | yes |
TCL1B_HUMAN | [view interactions] | Low throughput | no | no |
GAB2_HUMAN | [view interactions] | Low throughput | no | yes |
ILK_HUMAN | [view interactions] | Low throughput | no | no |
M3K8_HUMAN | [view interactions] | Low throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IRS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NPM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MARK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRIB3_HUMAN | [view interactions] | Low throughput | no | yes |
MERL_HUMAN | [view interactions] | Low throughput | no | yes |
PEPL_HUMAN | [view interactions] | Low throughput | no | yes |
SETB1_HUMAN | [view interactions] | Low throughput | no | yes |
UBP8_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
COMD1_HUMAN | [view interactions] | Low throughput | no | yes |
HDAC3_HUMAN | [view interactions] | Low throughput | no | yes |
SNF5_HUMAN | [view interactions] | Low throughput | no | yes |
ACTS_HUMAN | [view interactions] | Low throughput | no | no |
ASXL1_HUMAN | [view interactions] | Low throughput | no | no |
SMRC1_HUMAN | [view interactions] | Low throughput | no | yes |
SMRC2_HUMAN | [view interactions] | Low throughput | no | yes |
EZH2_HUMAN | [view interactions] | Low throughput | no | no |
HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SKP2_HUMAN | [view interactions] | Low throughput | no | yes |
PA2G4_HUMAN | [view interactions] | Low throughput | no | yes |
ERBB3_HUMAN | [view interactions] | Low throughput | no | yes |
TRI13_HUMAN | [view interactions] | Low throughput | no | no |
CTBP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NFKB1_HUMAN | [view interactions] | Low throughput | no | yes |
CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GLI1_HUMAN | [view interactions] | Low throughput | no | no |
SMAD3_HUMAN | [view interactions] | Low throughput | no | yes |
CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SMAD4_HUMAN | [view interactions] | Low throughput | no | yes |
PHLP1_HUMAN | [view interactions] | Low throughput | no | yes |
SMAD2_HUMAN | [view interactions] | Low throughput | no | yes |
FKBP5_HUMAN | [view interactions] | Low throughput | no | yes |
SMAD7_HUMAN | [view interactions] | Low throughput | no | yes |
PP2BA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
STK4_HUMAN | [view interactions] | Low throughput | no | yes |
PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
WDFY2_HUMAN | [view interactions] | Low throughput | no | no |
IQGA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
FOXO1_HUMAN | [view interactions] | Low throughput | no | yes |
MTOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBP4_HUMAN | [view interactions] | Low throughput | no | no |
HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MUL1_HUMAN | [view interactions] | Low throughput | no | no |
UBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IBTK_HUMAN | [view interactions] | Low throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BTBDA_HUMAN | [view interactions] | Low throughput | no | no |
RS27A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TERA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RL40_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PEBP4_HUMAN | [view interactions] | Low throughput | no | no |
VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KAT2B_HUMAN | [view interactions] | Low throughput | no | yes |
EP300_HUMAN | [view interactions] | Low throughput | no | yes |
SIR1_HUMAN | [view interactions] | Low throughput | no | yes |
RICTR_HUMAN | [view interactions] | Low throughput | no | yes |
PREX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PP2AA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ENOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CBP_HUMAN | [view interactions] | Low throughput | no | yes |
F110C_HUMAN | [view interactions] | Low throughput | no | yes |
GCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AKT2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITPR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
THOC4_HUMAN | [view interactions] | Low throughput | no | no |
THEM4_HUMAN | [view interactions] | Low throughput | no | no |
BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
SKI_HUMAN | [view interactions] | Low throughput | no | yes |
PKN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SIN1_HUMAN | [view interactions] | Low throughput | no | yes |
PHLP2_HUMAN | [view interactions] | Low throughput | no | yes |
NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CCNA2_HUMAN | [view interactions] | Low throughput | no | no |
PRKDC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TTC3_HUMAN | [view interactions] | Low throughput | no | yes |
RPTOR_HUMAN | [view interactions] | Low throughput | no | yes |
STK3_HUMAN | [view interactions] | Low throughput | no | yes |
CLK2_HUMAN | [view interactions] | Low throughput | no | yes |
HSPB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CSK_HUMAN | [view interactions] | Low throughput | no | yes |
HS90B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DAB2P_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CYLD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RGCC_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF6_HUMAN | [view interactions] | Low throughput | no | yes |
CNOT9_HUMAN | [view interactions] | Low throughput | no | yes |
CDC37_HUMAN | [view interactions] | Low throughput | no | yes |
JADE1_HUMAN | [view interactions] | Low throughput | no | yes |
PK3CA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
P85A_HUMAN | [view interactions] | Low throughput | no | yes |
NF2L2_HUMAN | [view interactions] | Low throughput | no | yes |
NHRF3_HUMAN | [view interactions] | Low throughput | no | no |
SIR6_HUMAN | [view interactions] | Low throughput | no | yes |
FOXO4_HUMAN | [view interactions] | Low throughput | no | no |
YBOX1_HUMAN | [view interactions] | Low throughput | no | yes |
2ABB_HUMAN | [view interactions] | Low throughput | no | yes |
CLIP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PKHO1_HUMAN | [view interactions] | Low throughput | no | no |
BAG1_HUMAN | [view interactions] | Low throughput | no | yes |
ARBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FHL1_HUMAN | [view interactions] | Low throughput | no | no |
KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ACAP1_HUMAN | [view interactions] | Low throughput | no | yes |
CDN1C_HUMAN | [view interactions] | Low throughput | no | yes |
SNAI1_HUMAN | [view interactions] | Low throughput | no | yes |
PP1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IRF3_HUMAN | [view interactions] | Low throughput | no | yes |
TBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NHRF1_HUMAN | [view interactions] | Low throughput | no | no |
CDN1B_HUMAN | [view interactions] | Low throughput | no | yes |
ACK1_HUMAN | [view interactions] | Low throughput | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TRI15_HUMAN | [view interactions] | Low throughput | no | no |
1433S_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PYGO2_HUMAN | [view interactions] | Low throughput | no | yes |
RARA_HUMAN | [view interactions] | Low throughput | no | no |
TRAF4_HUMAN | [view interactions] | Low throughput | no | yes |
2AAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
BCL10_HUMAN | [view interactions] | Low throughput | no | yes |
HSPB2_HUMAN | [view interactions] | Low throughput | no | yes |
ARRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GABR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ARRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RHES_HUMAN | [view interactions] | Low throughput | no | yes |
RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AGAP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
FGFR1_HUMAN | [view interactions] | Low throughput | no | yes |
BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
LT4R2_HUMAN | [view interactions] | Low throughput | no | no |
SRPK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DNMT1_HUMAN | [view interactions] | Low throughput | no | no |
FANCI_HUMAN | [view interactions] | Low throughput | no | yes |
FACD2_HUMAN | [view interactions] | Low throughput | no | no |
UBP1_HUMAN | [view interactions] | Low throughput | no | yes |
PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KS6B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
JIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBE2S_HUMAN | [view interactions] | Low throughput | no | no |
TOPB1_HUMAN | [view interactions] | Low throughput | no | yes |
CCNF_HUMAN | [view interactions] | Low throughput | no | no |
M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
KMT2D_HUMAN | [view interactions] | Low throughput | no | yes |
TERT_HUMAN | [view interactions] | Low throughput | no | no |
ARNT_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
G3P_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PARVB_HUMAN | [view interactions] | Low throughput | no | no |
PFKAP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MDM2_HUMAN | [view interactions] | Low throughput | no | yes |
IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BAIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BI2L1_HUMAN | [view interactions] | Low throughput | no | yes |
IWS1_HUMAN | [view interactions] | Low throughput | no | yes |
AKTS1_HUMAN | [view interactions] | Low throughput | no | yes |
IL3RB_HUMAN | [view interactions] | Low throughput | no | no |
PP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NIBA1_HUMAN | [view interactions] | Low throughput | no | no |
BIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
LMNA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HDAC6_HUMAN | [view interactions] | Low throughput | no | yes |
HMOX1_HUMAN | [view interactions] | Low throughput | no | no |
TISB_HUMAN | [view interactions] | Low throughput | no | no |
FOXO3_HUMAN | [view interactions] | Low throughput | no | yes |
B2L11_HUMAN | [view interactions] | Low throughput | no | yes |
PDE3A_HUMAN | [view interactions] | Low throughput | no | no |
PKN2_HUMAN | [view interactions] | Low throughput | no | yes |
SH3R1_HUMAN | [view interactions] | Low throughput | no | yes |
TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
BIEA_HUMAN | [view interactions] | Low throughput | no | yes |
SYTL1_HUMAN | [view interactions] | Low throughput | no | yes |
CAR11_HUMAN | [view interactions] | Low throughput | no | no |
TBCD7_HUMAN | [view interactions] | Low throughput | no | no |
PDK1_HUMAN | [view interactions] | Low throughput | no | yes |
LANC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PRGC1_HUMAN | [view interactions] | Low throughput | no | no |
T126B_HUMAN | [view interactions] | Low throughput | no | yes |
MAD1_HUMAN | [view interactions] | Low throughput | no | yes |
GSK3A_HUMAN | [view interactions] | Low throughput | no | yes |
FUBP2_HUMAN | [view interactions] | Low throughput | no | yes |
CHFR_HUMAN | [view interactions] | Low throughput | no | no |
FUS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FAF1_HUMAN | [view interactions] | Low throughput | no | yes |
ENPL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SOX2_HUMAN | [view interactions] | Low throughput | no | yes |
NQO1_HUMAN | [view interactions] | Low throughput | no | no |
RNF8_HUMAN | [view interactions] | Low throughput | no | yes |
COX2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MK04_HUMAN | [view interactions] | Low throughput | no | no |
BAP1_HUMAN | [view interactions] | Low throughput | no | yes |
KDM4B_HUMAN | [view interactions] | Low throughput | no | no |
WEE1_HUMAN | [view interactions] | Low throughput | no | yes |
PCGF2_HUMAN | [view interactions] | Low throughput | no | no |
CHSP1_HUMAN | [view interactions] | Low throughput | no | yes |
NCOR2_HUMAN | [view interactions] | Low throughput | no | yes |
KCD20_HUMAN | [view interactions] | Low throughput | no | yes |
GRB10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DP13A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NGB_HUMAN | [view interactions] | Low throughput | no | yes |
TCL1A_HUMAN | [view interactions] | Low throughput | no | no |
PCKGC_HUMAN | [view interactions] | Low throughput | no | no |
ESR1_HUMAN | [view interactions] | Low throughput | no | no |
B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
BTBD1_HUMAN | [view interactions] | High throughput | no | yes |
GALA_HUMAN | [view interactions] | High throughput | no | no |
PRUN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYH1_HUMAN | [view interactions] | High throughput | no | no |
THIO_HUMAN | [view interactions] | High throughput | no | yes |
KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ATX1_HUMAN | [view interactions] | High throughput | no | yes |
NLGN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
4EBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
THIC_HUMAN | [view interactions] | High throughput | no | yes |
CE57L_HUMAN | [view interactions] | High throughput | no | yes |
CTDS2_HUMAN | [view interactions] | High throughput | no | yes |
NOL4_HUMAN | [view interactions] | High throughput | no | no |
TRM2_HUMAN | [view interactions] | High throughput | no | yes |
TMCC2_HUMAN | [view interactions] | High throughput | no | yes |
MTUS2_HUMAN | [view interactions] | High throughput | no | yes |
CD44_HUMAN | [view interactions] | High throughput | no | yes |
CDK4_HUMAN | [view interactions] | High throughput | no | no |
CDK6_HUMAN | [view interactions] | High throughput | no | yes |
CDN2B_HUMAN | [view interactions] | High throughput | no | no |
CDN2C_HUMAN | [view interactions] | High throughput | no | yes |
EPHA2_HUMAN | [view interactions] | High throughput | no | no |
FGFR4_HUMAN | [view interactions] | High throughput | no | no |
GLIS2_HUMAN | [view interactions] | High throughput | no | no |
LATS2_HUMAN | [view interactions] | High throughput | no | yes |
MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
PGFRA_HUMAN | [view interactions] | High throughput | no | no |
RASF1_HUMAN | [view interactions] | High throughput | no | yes |
ARAF_HUMAN | [view interactions] | High throughput | no | yes |
PLXB1_HUMAN | [view interactions] | High throughput | no | yes |
CBLC_HUMAN | [view interactions] | High throughput | no | yes |
CCND2_HUMAN | [view interactions] | High throughput | no | yes |
CCNE1_HUMAN | [view interactions] | High throughput | no | no |
FETUA_HUMAN | [view interactions] | High throughput | no | no |
ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
APOH_HUMAN | [view interactions] | High throughput | no | no |
HIF1A_HUMAN | [view interactions] | High throughput | no | no |
KAT2A_HUMAN | [view interactions] | High throughput | no | no |
PMGE_HUMAN | [view interactions] | High throughput | no | no |
ERD22_HUMAN | [view interactions] | High throughput | no | yes |
DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MP2K6_HUMAN | [view interactions] | High throughput | no | yes |
NCOA4_HUMAN | [view interactions] | High throughput | no | no |
NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
P4K2B_HUMAN | [view interactions] | High throughput | no | yes |
SOX4_HUMAN | [view interactions] | High throughput | no | yes |
SRTD4_HUMAN | [view interactions] | High throughput | no | yes |
TEAD2_HUMAN | [view interactions] | High throughput | no | no |
RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P53_HUMAN | [view interactions] | High throughput | no | no |
DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TIE2_HUMAN | [view interactions] | High throughput | no | no |
ZHX1_HUMAN | [view interactions] | High throughput | no | no |
FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PK3CB_HUMAN | [view interactions] | High throughput | no | yes |
RPE_HUMAN | [view interactions] | High throughput | no | yes |
PDK2_HUMAN | [view interactions] | High throughput | no | yes |
KKCC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KS6A1_HUMAN | [view interactions] | High throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TBB5_HUMAN | [view interactions] | High throughput | no | yes |
1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PEBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COT2_HUMAN | [view interactions] | High throughput | no | no |
HBB_HUMAN | [view interactions] | High throughput | no | no |
PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IF4A1_HUMAN | [view interactions] | High throughput | no | no |
PSB4_HUMAN | [view interactions] | High throughput | no | yes |
GUAD_HUMAN | [view interactions] | High throughput | no | yes |
VPP2_HUMAN | [view interactions] | High throughput | no | yes |
PINK1_HUMAN | [view interactions] | High throughput | no | yes |
NOP56_HUMAN | [view interactions] | High throughput | no | yes |
FCERB_HUMAN | [view interactions] | High throughput | no | no |
RL1D1_HUMAN | [view interactions] | High throughput | no | yes |
BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H90B3_HUMAN | [view interactions] | High throughput | no | no |
CD81_HUMAN | [view interactions] | High throughput | no | no |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RCN2_HUMAN | [view interactions] | High throughput | no | yes |
ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AXA2L_HUMAN | [view interactions] | High throughput | no | no |
DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DSG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MPRI_HUMAN | [view interactions] | High throughput | no | yes |
CRNN_HUMAN | [view interactions] | High throughput | no | no |
SPRR3_HUMAN | [view interactions] | High throughput | no | no |
CYTB_HUMAN | [view interactions] | High throughput | no | no |
S10A3_HUMAN | [view interactions] | High throughput | no | no |
K1H2_HUMAN | [view interactions] | High throughput | no | no |
TCOF_HUMAN | [view interactions] | High throughput | no | yes |
KPCE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AKT3_HUMAN | [view interactions] | High throughput | no | yes |
TE2IP_HUMAN | [view interactions] | High throughput | no | yes |
SL9A1_HUMAN | [view interactions] | High throughput | no | no |
SGT1_HUMAN | [view interactions] | High throughput | no | no |
RBBP5_HUMAN | [view interactions] | High throughput | no | yes |
EGLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CUL1_HUMAN | [view interactions] | High throughput | no | yes |
DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
TRHDE_HUMAN | [view interactions] | High throughput | no | no |
M4K4_HUMAN | [view interactions] | High throughput | no | yes |
MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CD2AP_HUMAN | [view interactions] | High throughput | no | no |
UCK2_HUMAN | [view interactions] | High throughput | no | no |
WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INSR_HUMAN | [view interactions] | High throughput | no | yes |
KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLII_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKD2_HUMAN | [view interactions] | High throughput | no | yes |
INT3_HUMAN | [view interactions] | High throughput | no | yes |
CAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CABL1_HUMAN | [view interactions] | High throughput | no | no |
ATRX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
E2AK3_HUMAN | [view interactions] | High throughput | no | yes |
PKD1_HUMAN | [view interactions] | High throughput | no | yes |
KPYM_HUMAN | [view interactions] | High throughput | no | yes |
SHPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BUB1_HUMAN | [view interactions] | High throughput | no | no |
CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZDH18_HUMAN | [view interactions] | High throughput | no | yes |
FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
ZDH23_HUMAN | [view interactions] | High throughput | no | no |
MLH3_HUMAN | [view interactions] | High throughput | no | no |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
MSH2_HUMAN | [view interactions] | High throughput | no | yes |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PMS2_HUMAN | [view interactions] | High throughput | no | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STK11_HUMAN | [view interactions] | High throughput | no | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TLR2_HUMAN | [view interactions] | High throughput | no | no |
HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SOAT2_HUMAN | [view interactions] | High throughput | no | no |
UBR5_HUMAN | [view interactions] | High throughput | no | no |
CLAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GET4_HUMAN | [view interactions] | High throughput | no | yes |
CFAD_HUMAN | [view interactions] | High throughput | no | no |
CCNI_HUMAN | [view interactions] | High throughput | no | yes |
FNDC5_HUMAN | [view interactions] | High throughput | no | no |
ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DDX58_HUMAN | [view interactions] | High throughput | no | yes |
GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NMDE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FZR1_HUMAN | [view interactions] | High throughput | no | no |
PRS8_HUMAN | [view interactions] | High throughput | no | yes |
PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SOSD1_HUMAN | [view interactions] | High throughput | no | no |
MYPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RNF14_HUMAN | [view interactions] | High throughput | no | yes |
PTGDS_HUMAN | [view interactions] | High throughput | no | yes |
UMPS_HUMAN | [view interactions] | High throughput | no | no |
PTN3_HUMAN | [view interactions] | High throughput | no | yes |
DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYUB_HUMAN | [view interactions] | High throughput | no | yes |
EFMT3_HUMAN | [view interactions] | High throughput | no | no |
ST4A1_HUMAN | [view interactions] | High throughput | no | yes |
SRB4D_HUMAN | [view interactions] | High throughput | no | no |
UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDE3B_HUMAN | [view interactions] | High throughput | no | no |
ZN691_HUMAN | [view interactions] | High throughput | no | yes |
ABH15_HUMAN | [view interactions] | High throughput | no | yes |
AGR3_HUMAN | [view interactions] | High throughput | no | no |
CASC3_HUMAN | [view interactions] | High throughput | no | yes |
ESIP1_HUMAN | [view interactions] | High throughput | no | yes |
I13R2_HUMAN | [view interactions] | High throughput | no | no |
IL24_HUMAN | [view interactions] | High throughput | no | no |
VASP_HUMAN | [view interactions] | High throughput | no | yes |
OSGI1_HUMAN | [view interactions] | High throughput | no | no |
KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
MTA3_HUMAN | [view interactions] | High throughput | no | yes |
GEPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MRC2_HUMAN | [view interactions] | High throughput | no | yes |
CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S10AE_HUMAN | [view interactions] | High throughput | no | no |
CHK1_HUMAN | [view interactions] | High throughput | no | no |
RSLAB_HUMAN | [view interactions] | High throughput | no | no |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
SPB5_HUMAN | [view interactions] | High throughput | no | no |
TFF1_HUMAN | [view interactions] | High throughput | no | no |
ST14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
THRSP_HUMAN | [view interactions] | High throughput | no | no |
NSD3_HUMAN | [view interactions] | High throughput | no | yes |
PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEP76_HUMAN | [view interactions] | High throughput | no | yes |
MATK_HUMAN | [view interactions] | High throughput | no | yes |
DDT4L_HUMAN | [view interactions] | High throughput | no | no |
SPT6H_HUMAN | [view interactions] | High throughput | no | yes |
MESD_HUMAN | [view interactions] | High throughput | no | yes |
XAF1_HUMAN | [view interactions] | High throughput | no | yes |
KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RRAGA_HUMAN | [view interactions] | Computational | no | yes |
JAK1_HUMAN | [view interactions] | Computational | no | yes |
A1BG_HUMAN | [view interactions] | Computational | no | no |
RB_HUMAN | [view interactions] | Computational | no | yes |
FOXA2_HUMAN | [view interactions] | Computational | no | no |
BCL2_HUMAN | [view interactions] | Computational | no | no |
CATA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ARRS_HUMAN | [view interactions] | Computational | no | no |
EDNRA_HUMAN | [view interactions] | Computational | no | yes |
DEN1B_HUMAN | [view interactions] | Computational | no | yes |
M3K14_HUMAN | [view interactions] | Computational | no | yes |
LTOR2_HUMAN | [view interactions] | Computational | no | yes |
STRN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TNFA_HUMAN | [view interactions] | Computational | no | no |
P85B_HUMAN | [view interactions] | Computational | no | yes |
MEF2C_HUMAN | [view interactions] | Computational | no | yes |
VAV_HUMAN | [view interactions] | Computational | no | no |
LAMA1_HUMAN | [view interactions] | Computational | no | no |
OGT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RRAGB_HUMAN | [view interactions] | Computational | no | yes |
RARB_HUMAN | [view interactions] | Computational | no | yes |
CY24B_HUMAN | [view interactions] | Computational | no | no |
WASF2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PK3CD_HUMAN | [view interactions] | Computational | no | no |
CDN2A_HUMAN | [view interactions] | Computational | no | yes |
RASK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
LST8_HUMAN | [view interactions] | Computational | no | yes |
RXRA_HUMAN | [view interactions] | Computational | no | yes |
STA5A_HUMAN | [view interactions] | Computational | no | no |
DPTOR_HUMAN | [view interactions] | Computational | no | no |
SOCS3_HUMAN | [view interactions] | Computational | no | yes |
RXRB_HUMAN | [view interactions] | Computational | no | yes |
IL2_HUMAN | [view interactions] | Computational | no | no |
ASXL2_HUMAN | [view interactions] | Computational | no | no |
PRR5_HUMAN | [view interactions] | Computational | no | yes |
PML_HUMAN | [view interactions] | Computational | no | yes |
IL2RB_HUMAN | [view interactions] | Computational | no | no |
SHIP2_HUMAN | [view interactions] | Computational | no | yes |
S38A9_HUMAN | [view interactions] | Computational | no | yes |
STAT1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PLEK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MTSS1_HUMAN | [view interactions] | Computational | no | no |
RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
S1PR3_HUMAN | [view interactions] | Computational | no | no |
APAF_HUMAN | [view interactions] | Computational | no | no |
GBG1_HUMAN | [view interactions] | Computational | no | no |
MKRN1_HUMAN | [view interactions] | Computational | no | no |
CFLAR_HUMAN | [view interactions] | Computational | no | yes |
2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FHOD1_HUMAN | [view interactions] | Computational | no | no |
F262_HUMAN | [view interactions] | Computational | no | no |
CYFP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PDGFB_HUMAN | [view interactions] | Computational | no | yes |
GNDS_HUMAN | [view interactions] | Computational | no | yes |
IL2RA_HUMAN | [view interactions] | Computational | no | no |
P55G_HUMAN | [view interactions] | Computational | no | yes |
DVL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNAQ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNAZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EGF_HUMAN | [view interactions] | Computational | no | no |
CYC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
HSPB3_HUMAN | [view interactions] | Computational | no | no |
2A5B_HUMAN | [view interactions] | Computational | no | yes |
PP2AB_HUMAN | [view interactions] | Computational | no | yes |
TRPV1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GDIR2_HUMAN | [view interactions] | Computational | no | no |
NCF4_HUMAN | [view interactions] | Computational | no | no |
2AAB_HUMAN | [view interactions] | Computational | no | yes |
PGFRB_HUMAN | [view interactions] | Computational | no | yes |
MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MMP9_HUMAN | [view interactions] | Computational | no | no |
GDIR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PKHF2_HUMAN | [view interactions] | Computational | no | yes |
GON1_HUMAN | [view interactions] | Computational | no | yes |
IRS2_HUMAN | [view interactions] | Computational | no | yes |
SODC_HUMAN | [view interactions] | Computational | no | yes |
GRB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ABI1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
JUN_HUMAN | [view interactions] | Computational | no | yes |
CAD17_HUMAN | [view interactions] | Computational | no | no |
JAK3_HUMAN | [view interactions] | Computational | no | no |
PK3CG_HUMAN | [view interactions] | Computational | no | yes |
DEN1A_HUMAN | [view interactions] | Computational | no | no |
NOS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PHF20_HUMAN | [view interactions] | Computational | no | yes |
PI3R6_HUMAN | [view interactions] | Computational | no | yes |
GLUT4_HUMAN | [view interactions] | Computational | no | no |
PEBB_HUMAN | [view interactions] | Computational | no | no |
ITA6_HUMAN | [view interactions] | Computational | no | yes |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DKC1_HUMAN | [view interactions] | Computational | no | yes |
TXND9_HUMAN | [view interactions] | Computational | no | yes |
NKX31_HUMAN | [view interactions] | Computational | no | no |
RAC2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
STA5B_HUMAN | [view interactions] | Computational | no | yes |
TIAM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TEP1_HUMAN | [view interactions] | Computational | no | no |
2A5E_HUMAN | [view interactions] | Computational | no | yes |
BRPF1_HUMAN | [view interactions] | Computational | no | yes |
RHEB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
IF4E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
1433T_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CD19_HUMAN | [view interactions] | Computational | no | no |
NCF1_HUMAN | [view interactions] | Computational | no | no |
CCND1_HUMAN | [view interactions] | Computational | no | yes |
LTOR3_HUMAN | [view interactions] | Computational | no | yes |
2A5G_HUMAN | [view interactions] | Computational | no | yes |
IGF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNAI2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NRIP1_HUMAN | [view interactions] | Computational | no | yes |
MCL1_HUMAN | [view interactions] | Computational | no | yes |
GIT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SODE_HUMAN | [view interactions] | Computational | no | yes |
AXIN1_HUMAN | [view interactions] | Computational | no | yes |
SHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ITA2B_HUMAN | [view interactions] | Computational | no | no |
GNAI1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RXRG_HUMAN | [view interactions] | Computational | no | no |
ITB4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
IRF4_HUMAN | [view interactions] | Computational | no | no |
MYOD1_HUMAN | [view interactions] | Computational | no | no |
S1PR1_HUMAN | [view interactions] | Computational | no | no |
CD28_HUMAN | [view interactions] | Computational | no | no |
LTOR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MEF2A_HUMAN | [view interactions] | Computational | no | yes |
DAB1_HUMAN | [view interactions] | Computational | no | yes |
SODM_HUMAN | [view entry] [view interactions] | Computational | yes | no |
E2F1_HUMAN | [view interactions] | Computational | no | yes |
GAB1_HUMAN | [view interactions] | Computational | no | yes |
RRAGC_HUMAN | [view interactions] | Computational | no | yes |
PTK6_HUMAN | [view interactions] | Computational | no | yes |
GNAI3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
WASP_HUMAN | [view interactions] | Computational | no | yes |
CD86_HUMAN | [view interactions] | Computational | no | yes |
RRAGD_HUMAN | [view interactions] | Computational | no | yes |
GNAO_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ARF6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LAMC2_HUMAN | [view interactions] | Computational | no | no |
BRD1_HUMAN | [view interactions] | Computational | no | yes |
NOS2_HUMAN | [view interactions] | Computational | no | yes |
PLCG2_HUMAN | [view interactions] | Computational | no | yes |
NOTC4_HUMAN | [view interactions] | Computational | no | no |
PFKAL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
2ABA_HUMAN | [view interactions] | Computational | no | yes |
RELN_HUMAN | [view interactions] | Computational | no | no |
ANXA5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RHOU_HUMAN | [view interactions] | Computational | no | no |
SMO_HUMAN | [view interactions] | Computational | no | yes |
CD40L_HUMAN | [view interactions] | Computational | no | no |
RS6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VAV2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
IL6_HUMAN | [view interactions] | Computational | no | no |
DOCK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EDN1_HUMAN | [view interactions] | Computational | no | no |
CCM2_HUMAN | [view interactions] | Computational | no | yes |
CY24A_HUMAN | [view interactions] | Computational | no | no |
STAT3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LTOR4_HUMAN | [view interactions] | Computational | no | yes |
OCRL_HUMAN | [view interactions] | Computational | no | yes |
HXK2_HUMAN | [view interactions] | Computational | no | yes |
NOXA1_HUMAN | [view interactions] | Computational | no | yes |
MEF2D_HUMAN | [view interactions] | Computational | no | yes |
PFKAM_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CD80_HUMAN | [view interactions] | Computational | no | no |
LCAP_HUMAN | [view interactions] | Computational | no | yes |
GRB14_HUMAN | [view interactions] | Computational | no | yes |
ELAF_HUMAN | [view interactions] | Computational | no | no |
UB2D1_HUMAN | [view interactions] | Computational | no | yes |
PLCB2_HUMAN | [view interactions] | Computational | no | no |
RARG_HUMAN | [view interactions] | Computational | no | yes |
PARVA_HUMAN | [view interactions] | Computational | no | yes |
CASP9_HUMAN | [view interactions] | Computational | no | yes |
GON2_HUMAN | [view interactions] | Computational | no | no |
IL2RG_HUMAN | [view interactions] | Computational | no | no |
TENS1_HUMAN | [view interactions] | Computational | no | no |
PAXI_HUMAN | [view interactions] | Computational | no | yes |
GLI2_HUMAN | [view interactions] | Computational | no | yes |
PI3R5_HUMAN | [view interactions] | Computational | no | no |
2A5A_HUMAN | [view interactions] | Computational | no | yes |
ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
KEAP1_HUMAN | [view interactions] | Computational | no | yes |
TNR5_HUMAN | [view interactions] | Computational | no | no |
SRC8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
INS_HUMAN | [view interactions] | Computational | no | no |
JIP4_HUMAN | [view interactions] | Computational | no | yes |
ESR2_HUMAN | [view interactions] | Computational | no | no |
RHOG_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CRTC2_HUMAN | [view interactions] | Computational | no | yes |
GTPB4_HUMAN | [view interactions] | Computational | no | yes |
LAMB1_HUMAN | [view interactions] | Computational | no | yes |
LCK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
FSCN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EAF6_HUMAN | [view interactions] | Computational | no | no |
CAV1_HUMAN | [view interactions] | Computational | no | no |
PPARG_HUMAN | [view interactions] | Computational | no | yes |
SWP70_HUMAN | [view interactions] | Computational | no | no |
BRPF3_HUMAN | [view interactions] | Computational | no | yes |
RUNX2_HUMAN | [view interactions] | Computational | no | no |
DISC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ING5_HUMAN | [view interactions] | Computational | no | yes |
VLDLR_HUMAN | [view interactions] | Computational | no | yes |