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AKT1_HUMAN

AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis (PubMed, PubMed, PubMed, PubMed). This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates (PubMed, PubMed, PubMed, PubMed). Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported (PubMed, PubMed, PubMed, PubMed). AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface . Phosphorylation of PTPN1 at Ser-50 negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the attenuation of insulin signaling . Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for insulin-stimulated glucose transport (PubMed). AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at Ser-21 and GSK3B at Ser-9, resulting in inhibition of its kinase activity . Phosphorylation of GSK3 isoforms by AKT is also thought to be one mechanism by which cell proliferation is driven . AKT regulates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase) (PubMed). Phosphorylation of Ser-83 decreases MAP3K5 kinase activity stimulated by oxidative stress and thereby prevents apoptosis (PubMed). AKT mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at Ser-939 and Thr-1462, thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1 (PubMed). AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization (PubMed). In particular, FOXO1 is phosphorylated at Thr-24, Ser-256 and Ser-319 (PubMed). FOXO3 and FOXO4 are phosphorylated on equivalent sites (PubMed). AKT has an important role in the regulation of NF-kappa-B-dependent gene transcription and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein) (PubMed). The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1 (PubMed). AKT phosphorylates Ser-454 on ATP citrate lyase (ACLY), thereby potentially regulating ACLY activity and fatty acid synthesis . Activates the 3B isoform of cyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of Ser-273, resulting in reduced cyclic AMP levels and inhibition of lipolysis . Phosphorylates PIKFYVE on Ser-318, which results in increased PI(3)P-5 activity . The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the regulation cell proliferation and cell growth. AKT plays a role as key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation . Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I) (PubMed, PubMed). AKT mediates the antiapoptotic effects of IGF-I . Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly (PubMed). May be involved in the regulation of the placental development . Phosphorylates STK4/MST1 at Thr-120 and Thr-387 leading to inhibition of its: kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3 (PubMed). Phosphorylates STK3/MST2 at Thr-117 and Thr-384 leading to inhibition of its: cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation (PubMed, PubMed). Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation (PubMed). Phosphorylates RAF1 at Ser-259 and negatively regulates its activity (PubMed). Phosphorylation of BAD stimulates its pro-apoptotic activity (PubMed). Phosphorylates KAT6A at Thr-369 and this phosphorylation inhibits the interaction of KAT6A with PML and negatively regulates its acetylation activity towards p53/TP53 (PubMed). Phosphorylates palladin (PALLD), modulating cytoskeletal organization and cell motility (PubMed). Phosphorylates prohibitin (PHB), playing an important role in cell metabolism and proliferation (PubMed). Phosphorylates CDKN1A, for which phosphorylation at Thr-145 induces its release from CDK2 and cytoplasmic relocalization (PubMed). These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation (PubMed). Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation (PubMed). Phosphorylates PCK1 at Ser-90, reducing the binding affinity of PCK1 to oxaloacetate and changing PCK1 into an atypical protein kinase activity using GTP as donor (PubMed). Also acts as an activator of TMEM175 potassium channel activity in response to growth factors: forms the lysoK(GF) complex together with TMEM175 and acts by promoting TMEM175 channel activation, independently of its protein kinase activity (PubMed). [View more on UniProt]

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Position Amino acid Mutation Disease Overlap with binding region
17 Glu Lys Breastcancer(BC) -
17 Glu Lys Proteussyndrome(PROTEUSS) -
25 Arg Cys Cowdensyndrome6(CWS6) -
435 Thr Pro Cowdensyndrome6(CWS6) -
ELM instance Name Type Start End Partner
ELMI001976 DOC_WW_Pin1_4 DOC 89 94 -
ELMI001977 DOC_WW_Pin1_4 DOC 447 452 -
ELMI003847 MOD_CK2_1 MOD 126 132 -
ELMI001976 DOC_WW_Pin1_4 DOC 89 94 -
ELMI001977 DOC_WW_Pin1_4 DOC 447 452 -
ELMI003847 MOD_CK2_1 MOD 126 132 -

Molecular function

Term Name % Distance from the top of the tree Annotated in AKT1_HUMAN
GO:0043168 anion binding 41.1483 4 yes
GO:0000166 nucleotide binding 39.2344 4 yes
GO:0017076 purine nucleotide binding 39.2344 5 yes
GO:0032555 purine ribonucleotide binding 37.7990 4 yes
GO:0030554 adenyl nucleotide binding 36.8421 6 yes
GO:0035639 purine ribonucleoside triphosphate binding 36.8421 4 yes
GO:0032559 adenyl ribonucleotide binding 35.4067 5 yes
GO:0005524 ATP binding 34.4498 5 yes
GO:0043169 cation binding 31.1005 4 no
GO:0046872 metal ion binding 30.6220 5 no
GO:0019900 kinase binding 29.6651 4 yes
GO:0019901 protein kinase binding 28.2297 5 yes
GO:0003723 RNA binding 21.5311 4 no
GO:0016301 kinase activity 20.0957 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 19.6172 4 yes
GO:0004674 protein serine/threonine kinase activity 15.3110 4 yes
GO:0106310 protein serine kinase activity 14.8325 4 yes
GO:0042803 protein homodimerization activity 10.5263 4 yes
GO:0019887 protein kinase regulator activity 9.5694 4 yes
GO:0099106 ion channel regulator activity 5.2632 4 yes
GO:0004860 protein kinase inhibitor activity 4.7847 5 yes
GO:0019210 kinase inhibitor activity 4.7847 4 yes
GO:0035091 phosphatidylinositol binding 4.7847 4 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 4.3062 4 yes
GO:1901981 phosphatidylinositol phosphate binding 3.8278 5 yes
GO:0030291 protein serine/threonine kinase inhibitor activity 3.3493 6 yes
GO:0015459 potassium channel regulator activity 2.3923 5 yes
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1.4354 5 yes
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 0.9569 5 yes
GO:0099103 channel activator activity 0.9569 4 yes
GO:0099104 potassium channel activator activity 0.9569 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in AKT1_HUMAN
GO:0048522 positive regulation of cellular process 73.2057 4 yes
GO:0060255 regulation of macromolecule metabolic process 72.2488 4 yes
GO:0031323 regulation of cellular metabolic process 70.3349 4 yes
GO:0080090 regulation of primary metabolic process 69.3780 4 yes
GO:0048523 negative regulation of cellular process 62.6794 4 yes
GO:0009889 regulation of biosynthetic process 57.8947 4 yes
GO:0031326 regulation of cellular biosynthetic process 57.4163 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 56.4593 5 yes
GO:0009893 positive regulation of metabolic process 55.9809 4 yes
GO:0010646 regulation of cell communication 55.5024 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 53.5885 5 yes
GO:0009966 regulation of signal transduction 52.6316 4 yes
GO:0051246 regulation of protein metabolic process 51.6746 5 yes
GO:0051128 regulation of cellular component organization 51.1962 4 yes
GO:0010468 regulation of gene expression 50.2392 6 yes
GO:0031325 positive regulation of cellular metabolic process 48.8038 5 yes
GO:0009892 negative regulation of metabolic process 45.4545 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 43.5407 5 yes
GO:0048584 positive regulation of response to stimulus 40.6699 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 40.1914 5 yes
GO:1902531 regulation of intracellular signal transduction 39.7129 5 yes
GO:0031324 negative regulation of cellular metabolic process 39.7129 5 yes
GO:0023056 positive regulation of signaling 38.7560 4 yes
GO:0031399 regulation of protein modification process 38.2775 6 yes
GO:0010647 positive regulation of cell communication 37.7990 5 yes
GO:0051247 positive regulation of protein metabolic process 36.8421 6 yes
GO:0036211 protein modification process 36.3636 4 yes
GO:0042981 regulation of apoptotic process 36.3636 5 yes
GO:0043067 regulation of programmed cell death 36.3636 4 yes
GO:0043412 macromolecule modification 36.3636 4 yes
GO:0009891 positive regulation of biosynthetic process 36.3636 5 yes
GO:0051049 regulation of transport 35.8852 4 yes
GO:0031328 positive regulation of cellular biosynthetic process 35.8852 6 yes
GO:0051174 regulation of phosphorus metabolic process 35.4067 5 yes
GO:0019220 regulation of phosphate metabolic process 35.4067 6 yes
GO:0006996 organelle organization 34.9282 4 yes
GO:0009967 positive regulation of signal transduction 34.9282 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 34.4498 6 yes
GO:0006796 phosphate-containing compound metabolic process 33.9713 4 yes
GO:0048585 negative regulation of response to stimulus 33.4928 4 yes
GO:0010648 negative regulation of cell communication 33.0144 5 yes
GO:0023057 negative regulation of signaling 33.0144 4 yes
GO:0022607 cellular component assembly 32.5359 4 no
GO:0051252 regulation of RNA metabolic process 32.0574 5 yes
GO:0009894 regulation of catabolic process 31.5789 4 yes
GO:0009968 negative regulation of signal transduction 31.5789 5 yes
GO:0060341 regulation of cellular localization 31.5789 4 yes
GO:0042325 regulation of phosphorylation 31.1005 7 yes
GO:0008104 protein localization 31.1005 4 yes
GO:2001141 regulation of RNA biosynthetic process 30.6220 6 yes
GO:0006355 regulation of DNA-templated transcription 30.6220 7 yes
GO:0032880 regulation of protein localization 29.6651 5 yes
GO:0001932 regulation of protein phosphorylation 29.6651 7 yes
GO:0042127 regulation of cell population proliferation 28.7081 4 yes
GO:0051248 negative regulation of protein metabolic process 28.7081 6 yes
GO:0051130 positive regulation of cellular component organization 28.2297 5 no
GO:0009890 negative regulation of biosynthetic process 28.2297 5 yes
GO:0071310 cellular response to organic substance 28.2297 4 yes
GO:0031327 negative regulation of cellular biosynthetic process 28.2297 6 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 27.7512 6 yes
GO:0080134 regulation of response to stress 27.7512 4 yes
GO:0043066 negative regulation of apoptotic process 25.8373 6 yes
GO:0043069 negative regulation of programmed cell death 25.8373 5 yes
GO:0033043 regulation of organelle organization 25.3589 5 yes
GO:0045595 regulation of cell differentiation 25.3589 4 yes
GO:0051240 positive regulation of multicellular organismal process 25.3589 4 yes
GO:0044087 regulation of cellular component biogenesis 24.4019 4 yes
GO:0031401 positive regulation of protein modification process 24.4019 7 yes
GO:0051050 positive regulation of transport 23.9234 4 yes
GO:0051094 positive regulation of developmental process 23.9234 4 yes
GO:1902533 positive regulation of intracellular signal transduction 23.4450 6 yes
GO:0051338 regulation of transferase activity 23.4450 4 yes
GO:0043933 protein-containing complex organization 22.9665 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 22.9665 5 yes
GO:0045937 positive regulation of phosphate metabolic process 22.0096 7 yes
GO:0010562 positive regulation of phosphorus metabolic process 22.0096 6 yes
GO:1901701 cellular response to oxygen-containing compound 21.5311 4 yes
GO:0051726 regulation of cell cycle 21.5311 4 yes
GO:0016310 phosphorylation 21.5311 5 yes
GO:0043085 positive regulation of catalytic activity 21.0526 4 yes
GO:0007010 cytoskeleton organization 21.0526 5 no
GO:0010243 response to organonitrogen compound 21.0526 4 yes
GO:0010628 positive regulation of gene expression 21.0526 7 yes
GO:0042327 positive regulation of phosphorylation 20.5742 8 yes
GO:2000026 regulation of multicellular organismal development 20.5742 4 yes
GO:0043549 regulation of kinase activity 20.5742 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 20.5742 8 yes
GO:0071702 organic substance transport 20.5742 4 yes
GO:0030162 regulation of proteolysis 20.0957 6 yes
GO:0051129 negative regulation of cellular component organization 19.6172 5 yes
GO:0031400 negative regulation of protein modification process 19.6172 7 yes
GO:0141124 intracellular signaling cassette 19.6172 4 yes
GO:1902532 negative regulation of intracellular signal transduction 19.1388 6 yes
GO:1903829 positive regulation of protein localization 19.1388 5 yes
GO:2000145 regulation of cell motility 19.1388 4 yes
GO:0001934 positive regulation of protein phosphorylation 19.1388 8 yes
GO:0045859 regulation of protein kinase activity 19.1388 6 yes
GO:0010629 negative regulation of gene expression 19.1388 7 yes
GO:0071705 nitrogen compound transport 19.1388 4 yes
GO:0032101 regulation of response to external stimulus 19.1388 4 yes
GO:0051336 regulation of hydrolase activity 18.1818 4 yes
GO:0006468 protein phosphorylation 17.7033 5 yes
GO:0008284 positive regulation of cell population proliferation 17.7033 5 yes
GO:0009057 macromolecule catabolic process 17.7033 4 yes
GO:0009896 positive regulation of catabolic process 17.7033 5 yes
GO:0015031 protein transport 17.7033 4 yes
GO:0030334 regulation of cell migration 17.7033 5 yes
GO:0002684 positive regulation of immune system process 17.2249 4 yes
GO:0045936 negative regulation of phosphate metabolic process 17.2249 7 yes
GO:0007167 enzyme-linked receptor protein signaling pathway 17.2249 4 yes
GO:0010563 negative regulation of phosphorus metabolic process 17.2249 6 yes
GO:0030155 regulation of cell adhesion 17.2249 4 yes
GO:1901565 organonitrogen compound catabolic process 17.2249 4 yes
GO:1901699 cellular response to nitrogen compound 16.7464 4 yes
GO:0034762 regulation of transmembrane transport 16.7464 4 yes
GO:0043086 negative regulation of catalytic activity 16.7464 4 yes
GO:0045597 positive regulation of cell differentiation 16.7464 5 yes
GO:0042176 regulation of protein catabolic process 16.2679 5 yes
GO:0006915 apoptotic process 16.2679 4 yes
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 16.2679 5 yes
GO:0071417 cellular response to organonitrogen compound 16.2679 4 yes
GO:2001233 regulation of apoptotic signaling pathway 15.7895 5 yes
GO:0051347 positive regulation of transferase activity 15.7895 5 yes
GO:0018193 peptidyl-amino acid modification 15.7895 5 yes
GO:0031329 regulation of cellular catabolic process 15.7895 5 yes
GO:0031344 regulation of cell projection organization 15.7895 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 15.7895 6 yes
GO:0033993 response to lipid 15.3110 4 yes
GO:0042326 negative regulation of phosphorylation 15.3110 8 yes
GO:0050776 regulation of immune response 15.3110 4 yes
GO:0051254 positive regulation of RNA metabolic process 15.3110 6 yes
GO:1902680 positive regulation of RNA biosynthetic process 14.8325 7 yes
GO:0045893 positive regulation of DNA-templated transcription 14.8325 8 yes
GO:0010564 regulation of cell cycle process 14.8325 5 yes
GO:0060284 regulation of cell development 14.8325 5 yes
GO:0001933 negative regulation of protein phosphorylation 14.3541 8 yes
GO:0045862 positive regulation of proteolysis 14.3541 7 yes
GO:0006508 proteolysis 14.3541 4 yes
GO:0006886 intracellular protein transport 13.8756 4 yes
GO:0051051 negative regulation of transport 13.8756 4 yes
GO:0031347 regulation of defense response 13.8756 5 yes
GO:0033365 protein localization to organelle 13.3971 5 yes
GO:0033674 positive regulation of kinase activity 13.3971 6 yes
GO:0032870 cellular response to hormone stimulus 12.9187 4 yes
GO:1901873 regulation of post-translational protein modification 12.9187 7 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 12.9187 8 yes
GO:0040017 positive regulation of locomotion 12.9187 4 yes
GO:2000147 positive regulation of cell motility 12.9187 5 yes
GO:0043687 post-translational protein modification 12.9187 5 yes
GO:0030163 protein catabolic process 12.9187 4 yes
GO:0030335 positive regulation of cell migration 12.9187 6 yes
GO:0043269 regulation of monoatomic ion transport 12.4402 5 yes
GO:0045860 positive regulation of protein kinase activity 12.4402 7 yes
GO:0050865 regulation of cell activation 12.4402 4 yes
GO:0010506 regulation of autophagy 12.4402 6 yes
GO:0061024 membrane organization 12.4402 4 yes
GO:0071363 cellular response to growth factor stimulus 12.4402 4 yes
GO:1903050 regulation of proteolysis involved in protein catabolic process 11.9617 7 yes
GO:0051052 regulation of DNA metabolic process 11.9617 5 yes
GO:0001558 regulation of cell growth 11.4833 4 yes
GO:2001234 negative regulation of apoptotic signaling pathway 11.4833 6 yes
GO:0002694 regulation of leukocyte activation 11.4833 4 yes
GO:0045785 positive regulation of cell adhesion 11.4833 5 yes
GO:0009059 macromolecule biosynthetic process 11.4833 4 yes
GO:0051348 negative regulation of transferase activity 11.4833 5 yes
GO:0010975 regulation of neuron projection development 11.4833 7 yes
GO:0070647 protein modification by small protein conjugation or removal 11.4833 6 yes
GO:0031396 regulation of protein ubiquitination 11.4833 9 yes
GO:0045088 regulation of innate immune response 11.0048 5 yes
GO:0045732 positive regulation of protein catabolic process 11.0048 6 yes
GO:0002831 regulation of response to biotic stimulus 11.0048 4 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 11.0048 9 yes
GO:0051249 regulation of lymphocyte activation 11.0048 5 yes
GO:0010959 regulation of metal ion transport 11.0048 6 yes
GO:0036293 response to decreased oxygen levels 10.5263 4 yes
GO:0043632 modification-dependent macromolecule catabolic process 10.5263 5 yes
GO:0009895 negative regulation of catabolic process 10.5263 5 yes
GO:0051345 positive regulation of hydrolase activity 10.5263 5 yes
GO:0051603 proteolysis involved in protein catabolic process 10.5263 5 yes
GO:0019941 modification-dependent protein catabolic process 10.5263 6 yes
GO:0022407 regulation of cell-cell adhesion 10.5263 5 yes
GO:0071396 cellular response to lipid 10.5263 5 yes
GO:0071900 regulation of protein serine/threonine kinase activity 10.5263 7 yes
GO:0043434 response to peptide hormone 10.0478 4 yes
GO:0007346 regulation of mitotic cell cycle 10.0478 5 yes
GO:0050863 regulation of T cell activation 10.0478 6 yes
GO:0010038 response to metal ion 10.0478 4 yes
GO:0010608 post-transcriptional regulation of gene expression 10.0478 7 yes
GO:0061136 regulation of proteasomal protein catabolic process 10.0478 6 yes
GO:0062012 regulation of small molecule metabolic process 10.0478 4 yes
GO:1900180 regulation of protein localization to nucleus 10.0478 6 yes
GO:0032446 protein modification by small protein conjugation 9.5694 7 yes
GO:0033673 negative regulation of kinase activity 9.5694 6 yes
GO:0034097 response to cytokine 9.5694 4 yes
GO:0006109 regulation of carbohydrate metabolic process 9.5694 5 yes
GO:0006417 regulation of translation 9.5694 6 yes
GO:0050807 regulation of synapse organization 9.5694 5 yes
GO:0051054 positive regulation of DNA metabolic process 9.5694 6 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 9.0909 6 yes
GO:0034764 positive regulation of transmembrane transport 9.0909 5 yes
GO:1903052 positive regulation of proteolysis involved in protein catabolic process 9.0909 8 yes
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 9.0909 5 yes
GO:2001242 regulation of intrinsic apoptotic signaling pathway 9.0909 6 yes
GO:0050678 regulation of epithelial cell proliferation 9.0909 5 yes
GO:0010632 regulation of epithelial cell migration 9.0909 4 yes
GO:0051960 regulation of nervous system development 9.0909 5 yes
GO:0016567 protein ubiquitination 9.0909 8 yes
GO:0002683 negative regulation of immune system process 8.6124 4 yes
GO:0006469 negative regulation of protein kinase activity 8.6124 7 yes
GO:0006511 ubiquitin-dependent protein catabolic process 8.6124 7 yes
GO:0010639 negative regulation of organelle organization 8.6124 6 yes
GO:0052547 regulation of peptidase activity 8.6124 5 yes
GO:0052548 regulation of endopeptidase activity 8.6124 6 yes
GO:0018105 peptidyl-serine phosphorylation 8.6124 6 yes
GO:0018209 peptidyl-serine modification 8.6124 6 yes
GO:0071375 cellular response to peptide hormone stimulus 8.6124 5 yes
GO:1901800 positive regulation of proteasomal protein catabolic process 8.1340 7 yes
GO:2000116 regulation of cysteine-type endopeptidase activity 8.1340 7 yes
GO:0043467 regulation of generation of precursor metabolites and energy 8.1340 5 yes
GO:2001236 regulation of extrinsic apoptotic signaling pathway 8.1340 6 yes
GO:0050867 positive regulation of cell activation 8.1340 5 yes
GO:0010498 proteasomal protein catabolic process 8.1340 5 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 7.6555 7 yes
GO:0036294 cellular response to decreased oxygen levels 7.6555 5 yes
GO:1903828 negative regulation of protein localization 7.6555 5 yes
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 7.6555 6 yes
GO:0002696 positive regulation of leukocyte activation 7.6555 5 yes
GO:0045787 positive regulation of cell cycle 7.6555 5 yes
GO:0045861 negative regulation of proteolysis 7.6555 7 yes
GO:0007005 mitochondrion organization 7.6555 5 yes
GO:0048638 regulation of developmental growth 7.6555 4 yes
GO:0009416 response to light stimulus 7.6555 4 yes
GO:0051251 positive regulation of lymphocyte activation 7.6555 6 yes
GO:0051346 negative regulation of hydrolase activity 7.6555 5 yes
GO:0062013 positive regulation of small molecule metabolic process 7.6555 5 yes
GO:0062197 cellular response to chemical stress 7.6555 4 yes
GO:0019216 regulation of lipid metabolic process 7.6555 5 yes
GO:0022409 positive regulation of cell-cell adhesion 7.6555 6 yes
GO:0071453 cellular response to oxygen levels 7.6555 4 yes
GO:0072594 establishment of protein localization to organelle 7.6555 4 yes
GO:0032868 response to insulin 7.1770 5 yes
GO:1901987 regulation of cell cycle phase transition 7.1770 6 yes
GO:1905475 regulation of protein localization to membrane 7.1770 6 yes
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 7.1770 6 yes
GO:0043393 regulation of protein binding 7.1770 4 yes
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 7.1770 7 yes
GO:0045927 positive regulation of growth 7.1770 4 yes
GO:0006954 inflammatory response 7.1770 4 yes
GO:0050870 positive regulation of T cell activation 7.1770 7 yes
GO:0071345 cellular response to cytokine stimulus 7.1770 5 yes
GO:1900182 positive regulation of protein localization to nucleus 7.1770 6 yes
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 7.1770 6 yes
GO:0034504 protein localization to nucleus 6.6986 6 yes
GO:0034763 negative regulation of transmembrane transport 6.6986 5 yes
GO:0043270 positive regulation of monoatomic ion transport 6.6986 5 yes
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 6.6986 8 yes
GO:0006913 nucleocytoplasmic transport 6.6986 5 yes
GO:0046777 protein autophosphorylation 6.6986 6 yes
GO:0007162 negative regulation of cell adhesion 6.6986 5 yes
GO:0008286 insulin receptor signaling pathway 6.6986 6 yes
GO:0048660 regulation of smooth muscle cell proliferation 6.6986 5 yes
GO:0050679 positive regulation of epithelial cell proliferation 6.6986 6 yes
GO:0051169 nuclear transport 6.6986 4 yes
GO:0010594 regulation of endothelial cell migration 6.6986 5 yes
GO:0010634 positive regulation of epithelial cell migration 6.6986 5 yes
GO:0010821 regulation of mitochondrion organization 6.6986 6 yes
GO:0016241 regulation of macroautophagy 6.6986 7 yes
GO:0019221 cytokine-mediated signaling pathway 6.6986 4 yes
GO:0071902 positive regulation of protein serine/threonine kinase activity 6.6986 8 yes
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 6.2201 7 yes
GO:0032869 cellular response to insulin stimulus 6.2201 6 yes
GO:1901990 regulation of mitotic cell cycle phase transition 6.2201 6 yes
GO:0034599 cellular response to oxidative stress 6.2201 4 yes
GO:0038127 ERBB signaling pathway 6.2201 6 yes
GO:0040013 negative regulation of locomotion 6.2201 4 yes
GO:2000146 negative regulation of cell motility 6.2201 5 yes
GO:0051091 positive regulation of DNA-binding transcription factor activity 6.2201 4 yes
GO:0019318 hexose metabolic process 6.2201 4 yes
GO:0097305 response to alcohol 6.2201 4 yes
GO:0032006 regulation of TOR signaling 6.2201 6 yes
GO:1901874 negative regulation of post-translational protein modification 5.7416 8 yes
GO:1903321 negative regulation of protein modification by small protein conjugation or removal 5.7416 9 yes
GO:1904375 regulation of protein localization to cell periphery 5.7416 6 yes
GO:0043255 regulation of carbohydrate biosynthetic process 5.7416 5 yes
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 5.7416 7 yes
GO:0006006 glucose metabolic process 5.7416 5 yes
GO:0045913 positive regulation of carbohydrate metabolic process 5.7416 5 yes
GO:0010466 negative regulation of peptidase activity 5.7416 6 yes
GO:0010827 regulation of glucose transmembrane transport 5.7416 5 yes
GO:0010951 negative regulation of endopeptidase activity 5.7416 7 yes
GO:0030336 negative regulation of cell migration 5.7416 6 yes
GO:0090068 positive regulation of cell cycle process 5.7416 6 yes
GO:1901654 response to ketone 5.2632 4 yes
GO:1901796 regulation of signal transduction by p53 class mediator 5.2632 6 yes
GO:1903432 regulation of TORC1 signaling 5.2632 7 yes
GO:0042593 glucose homeostasis 5.2632 4 yes
GO:1905477 positive regulation of protein localization to membrane 5.2632 6 yes
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5.2632 7 yes
GO:2000117 negative regulation of cysteine-type endopeptidase activity 5.2632 8 yes
GO:0045834 positive regulation of lipid metabolic process 5.2632 5 yes
GO:0007173 epidermal growth factor receptor signaling pathway 5.2632 7 yes
GO:0060491 regulation of cell projection assembly 5.2632 5 yes
GO:0071241 cellular response to inorganic substance 5.2632 4 yes
GO:0030307 positive regulation of cell growth 5.2632 5 yes
GO:0031345 negative regulation of cell projection organization 5.2632 6 yes
GO:0031397 negative regulation of protein ubiquitination 5.2632 10 yes
GO:0033135 regulation of peptidyl-serine phosphorylation 4.7847 8 yes
GO:1902115 regulation of organelle assembly 4.7847 5 yes
GO:1902806 regulation of cell cycle G1/S phase transition 4.7847 7 yes
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction 4.7847 5 yes
GO:0043535 regulation of blood vessel endothelial cell migration 4.7847 6 yes
GO:0001936 regulation of endothelial cell proliferation 4.7847 6 yes
GO:0045931 positive regulation of mitotic cell cycle 4.7847 6 yes
GO:0006606 protein import into nucleus 4.7847 5 yes
GO:0048661 positive regulation of smooth muscle cell proliferation 4.7847 6 yes
GO:0051170 import into nucleus 4.7847 6 yes
GO:0010906 regulation of glucose metabolic process 4.7847 5 yes
GO:0062207 regulation of pattern recognition receptor signaling pathway 4.7847 5 yes
GO:0018107 peptidyl-threonine phosphorylation 4.7847 6 yes
GO:0018210 peptidyl-threonine modification 4.7847 6 yes
GO:0071248 cellular response to metal ion 4.7847 5 yes
GO:0071901 negative regulation of protein serine/threonine kinase activity 4.7847 8 yes
GO:0031330 negative regulation of cellular catabolic process 4.7847 6 yes
GO:0120032 regulation of plasma membrane bounded cell projection assembly 4.7847 6 yes
GO:1901655 cellular response to ketone 4.3062 5 yes
GO:0032881 regulation of polysaccharide metabolic process 4.3062 5 yes
GO:0032885 regulation of polysaccharide biosynthetic process 4.3062 6 yes
GO:0033138 positive regulation of peptidyl-serine phosphorylation 4.3062 9 yes
GO:1903076 regulation of protein localization to plasma membrane 4.3062 7 yes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 4.3062 7 yes
GO:0000302 response to reactive oxygen species 4.3062 4 yes
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 4.3062 7 yes
GO:0001938 positive regulation of endothelial cell proliferation 4.3062 7 yes
GO:0046324 regulation of glucose import 4.3062 6 yes
GO:0046890 regulation of lipid biosynthetic process 4.3062 5 yes
GO:0048009 insulin-like growth factor receptor signaling pathway 4.3062 6 yes
GO:0010507 negative regulation of autophagy 4.3062 7 yes
GO:0010595 positive regulation of endothelial cell migration 4.3062 6 yes
GO:0051881 regulation of mitochondrial membrane potential 4.3062 4 yes
GO:0010828 positive regulation of glucose transmembrane transport 4.3062 6 yes
GO:0015980 energy derivation by oxidation of organic compounds 4.3062 4 yes
GO:0070849 response to epidermal growth factor 4.3062 4 yes
GO:0071364 cellular response to epidermal growth factor stimulus 4.3062 5 yes
GO:0030855 epithelial cell differentiation 4.3062 4 yes
GO:0097306 cellular response to alcohol 4.3062 5 yes
GO:0099175 regulation of postsynapse organization 4.3062 6 yes
GO:1904377 positive regulation of protein localization to cell periphery 3.8278 6 yes
GO:1905952 regulation of lipid localization 3.8278 4 yes
GO:0001649 osteoblast differentiation 3.8278 4 yes
GO:0002685 regulation of leukocyte migration 3.8278 4 yes
GO:0005979 regulation of glycogen biosynthetic process 3.8278 7 yes
GO:0006112 energy reserve metabolic process 3.8278 5 yes
GO:0048639 positive regulation of developmental growth 3.8278 5 yes
GO:0051100 negative regulation of binding 3.8278 4 yes
GO:0010467 gene expression 3.8278 5 yes
GO:0010762 regulation of fibroblast migration 3.8278 6 yes
GO:0060078 regulation of postsynaptic membrane potential 3.8278 4 yes
GO:0010962 regulation of glucan biosynthetic process 3.8278 7 yes
GO:0070873 regulation of glycogen metabolic process 3.8278 6 yes
GO:0022408 negative regulation of cell-cell adhesion 3.8278 6 yes
GO:0032091 negative regulation of protein binding 3.8278 5 yes
GO:0032368 regulation of lipid transport 3.8278 5 yes
GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3.3493 7 yes
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3.3493 8 yes
GO:0034614 cellular response to reactive oxygen species 3.3493 5 yes
GO:1903311 regulation of mRNA metabolic process 3.3493 6 yes
GO:0043536 positive regulation of blood vessel endothelial cell migration 3.3493 7 yes
GO:0044042 glucan metabolic process 3.3493 5 yes
GO:0001667 ameboidal-type cell migration 3.3493 4 yes
GO:0002028 regulation of sodium ion transport 3.3493 7 yes
GO:0005976 polysaccharide metabolic process 3.3493 4 yes
GO:0005977 glycogen metabolic process 3.3493 6 yes
GO:0046326 positive regulation of glucose import 3.3493 7 yes
GO:0046889 positive regulation of lipid biosynthetic process 3.3493 6 yes
GO:0007009 plasma membrane organization 3.3493 5 yes
GO:0010565 regulation of cellular ketone metabolic process 3.3493 5 yes
GO:0060079 excitatory postsynaptic potential 3.3493 5 yes
GO:0010907 positive regulation of glucose metabolic process 3.3493 6 yes
GO:0070585 protein localization to mitochondrion 3.3493 6 yes
GO:1901989 positive regulation of cell cycle phase transition 2.8708 7 yes
GO:0034612 response to tumor necrosis factor 2.8708 5 yes
GO:0035924 cellular response to vascular endothelial growth factor stimulus 2.8708 5 yes
GO:1903078 positive regulation of protein localization to plasma membrane 2.8708 7 yes
GO:0039531 regulation of cytoplasmic pattern recognition receptor signaling pathway 2.8708 6 yes
GO:1990089 response to nerve growth factor 2.8708 4 yes
GO:1990090 cellular response to nerve growth factor stimulus 2.8708 5 yes
GO:0045428 regulation of nitric oxide biosynthetic process 2.8708 5 yes
GO:0007249 canonical NF-kappaB signal transduction 2.8708 5 yes
GO:0008637 apoptotic mitochondrial changes 2.8708 6 yes
GO:0009411 response to UV 2.8708 5 yes
GO:0051341 regulation of oxidoreductase activity 2.8708 4 yes
GO:0010631 epithelial cell migration 2.8708 5 yes
GO:0016051 carbohydrate biosynthetic process 2.8708 4 yes
GO:0016242 negative regulation of macroautophagy 2.8708 8 yes
GO:0019217 regulation of fatty acid metabolic process 2.8708 6 yes
GO:0080164 regulation of nitric oxide metabolic process 2.8708 4 yes
GO:0090199 regulation of release of cytochrome c from mitochondria 2.8708 7 yes
GO:0032008 positive regulation of TOR signaling 2.8708 7 yes
GO:1901992 positive regulation of mitotic cell cycle phase transition 2.3923 7 yes
GO:1902017 regulation of cilium assembly 2.3923 6 yes
GO:1903038 negative regulation of leukocyte cell-cell adhesion 2.3923 7 yes
GO:1904029 regulation of cyclin-dependent protein kinase activity 2.3923 5 yes
GO:1904263 positive regulation of TORC1 signaling 2.3923 8 yes
GO:0042692 muscle cell differentiation 2.3923 4 yes
GO:1905953 negative regulation of lipid localization 2.3923 4 yes
GO:2000008 regulation of protein localization to cell surface 2.3923 6 yes
GO:0043276 anoikis 2.3923 5 yes
GO:0043488 regulation of mRNA stability 2.3923 4 yes
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 2.3923 7 yes
GO:0045725 positive regulation of glycogen biosynthetic process 2.3923 7 yes
GO:0045838 positive regulation of membrane potential 2.3923 4 yes
GO:0046620 regulation of organ growth 2.3923 4 yes
GO:0048568 embryonic organ development 2.3923 4 yes
GO:0008593 regulation of Notch signaling pathway 2.3923 5 yes
GO:0050994 regulation of lipid catabolic process 2.3923 5 yes
GO:0010763 positive regulation of fibroblast migration 2.3923 7 yes
GO:0010918 positive regulation of mitochondrial membrane potential 2.3923 5 yes
GO:0061013 regulation of mRNA catabolic process 2.3923 5 yes
GO:0062014 negative regulation of small molecule metabolic process 2.3923 5 yes
GO:0070875 positive regulation of glycogen metabolic process 2.3923 6 yes
GO:0071675 regulation of mononuclear cell migration 2.3923 5 yes
GO:0071887 leukocyte apoptotic process 2.3923 5 yes
GO:0072655 establishment of protein localization to mitochondrion 2.3923 5 yes
GO:0031641 regulation of myelination 2.3923 4 yes
GO:0031929 TOR signaling 2.3923 4 yes
GO:0032369 negative regulation of lipid transport 2.3923 5 yes
GO:1901099 negative regulation of signal transduction in absence of ligand 2.3923 6 yes
GO:0032768 regulation of monooxygenase activity 1.9139 5 yes
GO:0032890 regulation of organic acid transport 1.9139 5 yes
GO:1902808 positive regulation of cell cycle G1/S phase transition 1.9139 8 yes
GO:0034694 response to prostaglandin 1.9139 4 yes
GO:0034695 response to prostaglandin E 1.9139 5 yes
GO:1904407 positive regulation of nitric oxide metabolic process 1.9139 5 yes
GO:0043217 myelin maintenance 1.9139 6 yes
GO:2000074 regulation of type B pancreatic cell development 1.9139 6 yes
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 1.9139 6 yes
GO:0043542 endothelial cell migration 1.9139 6 yes
GO:2000401 regulation of lymphocyte migration 1.9139 6 yes
GO:0045429 positive regulation of nitric oxide biosynthetic process 1.9139 6 yes
GO:0045833 negative regulation of lipid metabolic process 1.9139 5 yes
GO:0046320 regulation of fatty acid oxidation 1.9139 7 yes
GO:0046622 positive regulation of organ growth 1.9139 5 yes
GO:0008643 carbohydrate transport 1.9139 5 yes
GO:0051146 striated muscle cell differentiation 1.9139 5 yes
GO:0051353 positive regulation of oxidoreductase activity 1.9139 5 yes
GO:0071379 cellular response to prostaglandin stimulus 1.9139 5 yes
GO:0071380 cellular response to prostaglandin E stimulus 1.9139 6 yes
GO:0072595 maintenance of protein localization in organelle 1.9139 4 yes
GO:0090201 negative regulation of release of cytochrome c from mitochondria 1.9139 7 yes
GO:0031663 lipopolysaccharide-mediated signaling pathway 1.9139 4 yes
GO:0031998 regulation of fatty acid beta-oxidation 1.9139 6 yes
GO:0032069 regulation of nuclease activity 1.9139 5 yes
GO:0032770 positive regulation of monooxygenase activity 1.4354 6 yes
GO:0032891 negative regulation of organic acid transport 1.4354 5 yes
GO:0038061 non-canonical NF-kappaB signal transduction 1.4354 5 yes
GO:1903719 regulation of I-kappaB phosphorylation 1.4354 8 yes
GO:0039532 negative regulation of cytoplasmic pattern recognition receptor signaling pathway 1.4354 5 yes
GO:1904031 positive regulation of cyclin-dependent protein kinase activity 1.4354 6 yes
GO:2000010 positive regulation of protein localization to cell surface 1.4354 6 yes
GO:0043534 blood vessel endothelial cell migration 1.4354 7 yes
GO:2000191 regulation of fatty acid transport 1.4354 6 yes
GO:2000192 negative regulation of fatty acid transport 1.4354 6 yes
GO:0000271 polysaccharide biosynthetic process 1.4354 5 yes
GO:0045598 regulation of fat cell differentiation 1.4354 5 yes
GO:0002686 negative regulation of leukocyte migration 1.4354 5 yes
GO:0045746 negative regulation of Notch signaling pathway 1.4354 6 yes
GO:0003376 sphingosine-1-phosphate receptor signaling pathway 1.4354 4 yes
GO:0005978 glycogen biosynthetic process 1.4354 7 yes
GO:0009250 glucan biosynthetic process 1.4354 6 yes
GO:0050999 regulation of nitric-oxide synthase activity 1.4354 6 yes
GO:0051000 positive regulation of nitric-oxide synthase activity 1.4354 7 yes
GO:0010746 regulation of long-chain fatty acid import across plasma membrane 1.4354 5 yes
GO:0010748 negative regulation of long-chain fatty acid import across plasma membrane 1.4354 6 yes
GO:0010761 fibroblast migration 1.4354 5 yes
GO:0060644 mammary gland epithelial cell differentiation 1.4354 5 yes
GO:0070227 lymphocyte apoptotic process 1.4354 6 yes
GO:0071356 cellular response to tumor necrosis factor 1.4354 6 yes
GO:0072656 maintenance of protein location in mitochondrion 1.4354 5 yes
GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 1.4354 7 yes
GO:0032070 regulation of deoxyribonuclease activity 1.4354 6 yes
GO:0140212 regulation of long-chain fatty acid import into cell 1.4354 7 yes
GO:0032071 regulation of endodeoxyribonuclease activity 1.4354 7 yes
GO:0140213 negative regulation of long-chain fatty acid import into cell 1.4354 7 yes
GO:0032075 positive regulation of nuclease activity 1.4354 6 yes
GO:0160049 negative regulation of cGAS/STING signaling pathway 1.4354 6 yes
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 1.4354 8 yes
GO:0032287 peripheral nervous system myelin maintenance 1.4354 7 yes
GO:1902018 negative regulation of cilium assembly 0.9569 7 yes
GO:1902116 negative regulation of organelle assembly 0.9569 6 yes
GO:0035655 interleukin-18-mediated signaling pathway 0.9569 5 yes
GO:1903326 regulation of tRNA metabolic process 0.9569 6 yes
GO:1903721 positive regulation of I-kappaB phosphorylation 0.9569 9 yes
GO:1905550 regulation of protein localization to endoplasmic reticulum 0.9569 6 yes
GO:1905552 positive regulation of protein localization to endoplasmic reticulum 0.9569 6 yes
GO:1990418 response to insulin-like growth factor stimulus 0.9569 4 yes
GO:2000235 regulation of tRNA processing 0.9569 7 yes
GO:2000402 negative regulation of lymphocyte migration 0.9569 7 yes
GO:0002042 cell migration involved in sprouting angiogenesis 0.9569 8 yes
GO:0045600 positive regulation of fat cell differentiation 0.9569 6 yes
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 0.9569 6 yes
GO:0045922 negative regulation of fatty acid metabolic process 0.9569 6 yes
GO:0046322 negative regulation of fatty acid oxidation 0.9569 7 yes
GO:0006924 activation-induced cell death of T cells 0.9569 8 yes
GO:0046686 response to cadmium ion 0.9569 5 yes
GO:0050995 negative regulation of lipid catabolic process 0.9569 6 yes
GO:0052031 symbiont-mediated perturbation of host defense response 0.9569 4 yes
GO:0052200 response to host defenses 0.9569 4 yes
GO:0010765 positive regulation of sodium ion transport 0.9569 6 yes
GO:0060416 response to growth hormone 0.9569 5 yes
GO:0060674 placenta blood vessel development 0.9569 4 yes
GO:0060709 glycogen cell differentiation involved in embryonic placenta development 0.9569 4 yes
GO:0060716 labyrinthine layer blood vessel development 0.9569 5 yes
GO:0070141 response to UV-A 0.9569 6 yes
GO:0070231 T cell apoptotic process 0.9569 7 yes
GO:0019049 virus-mediated perturbation of host defense response 0.9569 4 yes
GO:0071276 cellular response to cadmium ion 0.9569 6 yes
GO:0071404 cellular response to low-density lipoprotein particle stimulus 0.9569 4 yes
GO:0071676 negative regulation of mononuclear cell migration 0.9569 6 yes
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 0.9569 6 yes
GO:0097012 response to granulocyte macrophage colony-stimulating factor 0.9569 5 yes
GO:0110002 regulation of tRNA methylation 0.9569 8 yes
GO:0031999 negative regulation of fatty acid beta-oxidation 0.9569 7 yes
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus 0.9569 5 yes
GO:0032077 positive regulation of deoxyribonuclease activity 0.9569 7 yes
GO:0150031 regulation of protein localization to lysosome 0.9569 6 yes
GO:0032079 positive regulation of endodeoxyribonuclease activity 0.9569 8 yes
GO:0150033 negative regulation of protein localization to lysosome 0.9569 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CREB1_HUMAN [view interactions] Low throughput no yes
RON_HUMAN [view interactions] Low throughput no yes
TBCD4_HUMAN [view interactions] Low throughput no yes
CTND1_HUMAN [view entry] [view interactions] Low throughput yes no
NOTC1_HUMAN [view entry] [view interactions] Low throughput yes yes
ITPR3_HUMAN [view interactions] Low throughput no yes
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
GATA2_HUMAN [view interactions] Low throughput no yes
TRMB_HUMAN [view interactions] Low throughput no yes
ANDR_HUMAN [view interactions] Low throughput no no
GATA1_HUMAN [view interactions] Low throughput no no
AKTIP_HUMAN [view interactions] Low throughput no yes
SH2B2_HUMAN [view interactions] Low throughput no yes
IRAK1_HUMAN [view interactions] Low throughput no yes
KAT6A_HUMAN [view interactions] Low throughput no yes
MTCP1_HUMAN [view interactions] Low throughput no no
RHG07_HUMAN [view interactions] Low throughput no no
TSC1_HUMAN [view entry] [view interactions] Low throughput yes yes
MK08_HUMAN [view interactions] Low throughput no yes
TSC2_HUMAN [view entry] [view interactions] Low throughput yes yes
MK09_HUMAN [view interactions] Low throughput no yes
KPCT_HUMAN [view interactions] Low throughput no no
KLHL3_HUMAN [view interactions] Low throughput no no
NR4A1_HUMAN [view interactions] Low throughput no yes
KC1D_HUMAN [view entry] [view interactions] Low throughput yes yes
M3K11_HUMAN [view interactions] Low throughput no yes
BCL3_HUMAN [view interactions] Low throughput no yes
MP2K4_HUMAN [view interactions] Low throughput no yes
ITB3_HUMAN [view entry] [view interactions] Low throughput yes no
TCL1B_HUMAN [view interactions] Low throughput no no
RAC1_HUMAN [view entry] [view interactions] Low throughput yes no
GAB2_HUMAN [view interactions] Low throughput no yes
ZRAN1_HUMAN [view interactions] Low throughput no yes
ILK_HUMAN [view interactions] Low throughput no no
KANK1_HUMAN [view interactions] Low throughput no yes
M3K8_HUMAN [view interactions] Low throughput no yes
SP1_HUMAN [view interactions] Low throughput no yes
1433Z_HUMAN [view entry] [view interactions] Low throughput yes yes
SP3_HUMAN [view interactions] Low throughput no no
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
SSH1_HUMAN [view interactions] Low throughput no yes
NPM_HUMAN [view entry] [view interactions] Low throughput yes yes
FBX31_HUMAN [view entry] [view interactions] Low throughput yes yes
TRIB3_HUMAN [view interactions] Low throughput no yes
MARK2_HUMAN [view entry] [view interactions] Low throughput yes yes
PI51C_HUMAN [view entry] [view interactions] Low throughput yes yes
PEPL_HUMAN [view interactions] Low throughput no yes
MERL_HUMAN [view interactions] Low throughput no yes
BABA1_HUMAN [view interactions] Low throughput no yes
SETB1_HUMAN [view interactions] Low throughput no yes
EMSY_HUMAN [view interactions] Low throughput no yes
COMD1_HUMAN [view interactions] Low throughput no yes
UBP8_HUMAN [view entry] [view interactions] Low throughput yes no
BEX1_HUMAN [view interactions] Low throughput no yes
HDAC3_HUMAN [view interactions] Low throughput no yes
UBP11_HUMAN [view interactions] Low throughput no yes
SNF5_HUMAN [view interactions] Low throughput no yes
OTUB2_HUMAN [view interactions] Low throughput no no
ASXL1_HUMAN [view interactions] Low throughput no no
ACTS_HUMAN [view interactions] Low throughput no no
OTUD5_HUMAN [view interactions] Low throughput no yes
SMRC1_HUMAN [view interactions] Low throughput no yes
OTU6A_HUMAN [view interactions] Low throughput no no
SMRC2_HUMAN [view interactions] Low throughput no yes
CAST1_HUMAN [view interactions] Low throughput no yes
EZH2_HUMAN [view interactions] Low throughput no no
UBP10_HUMAN [view interactions] Low throughput no yes
HSP74_HUMAN [view entry] [view interactions] Low throughput yes yes
SKP2_HUMAN [view interactions] Low throughput no yes
PA2G4_HUMAN [view interactions] Low throughput no yes
ERBB3_HUMAN [view interactions] Low throughput no yes
TRI13_HUMAN [view interactions] Low throughput no no
CTBP1_HUMAN [view entry] [view interactions] Low throughput yes yes
NFKB1_HUMAN [view interactions] Low throughput no yes
CALM2_HUMAN [view entry] [view interactions] Low throughput yes yes
SMAD3_HUMAN [view interactions] Low throughput no yes
CALM3_HUMAN [view entry] [view interactions] Low throughput yes yes
SMAD4_HUMAN [view interactions] Low throughput no yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
SMAD2_HUMAN [view interactions] Low throughput no yes
PHLP1_HUMAN [view interactions] Low throughput no yes
SMAD7_HUMAN [view interactions] Low throughput no yes
FKBP5_HUMAN [view interactions] Low throughput no yes
STK4_HUMAN [view interactions] Low throughput no yes
PP2BA_HUMAN [view entry] [view interactions] Low throughput yes yes
WDFY2_HUMAN [view interactions] Low throughput no no
PTEN_HUMAN [view entry] [view interactions] Low throughput yes yes
FOXO1_HUMAN [view interactions] Low throughput no yes
IQGA1_HUMAN [view entry] [view interactions] Low throughput yes no
MTOR_HUMAN [view entry] [view interactions] Low throughput yes yes
HS90A_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP4_HUMAN [view interactions] Low throughput no no
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
MUL1_HUMAN [view interactions] Low throughput no no
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
IBTK_HUMAN [view interactions] Low throughput no yes
RS27A_HUMAN [view entry] [view interactions] Low throughput yes yes
BTBDA_HUMAN [view interactions] Low throughput no no
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
TERA_HUMAN [view entry] [view interactions] Low throughput yes yes
PEBP4_HUMAN [view interactions] Low throughput no no
VIME_HUMAN [view entry] [view interactions] Low throughput yes no
EP300_HUMAN [view interactions] Low throughput no yes
GBB1_HUMAN [view entry] [view interactions] Low throughput yes yes
KAT2B_HUMAN [view interactions] Low throughput no yes
SIR1_HUMAN [view interactions] Low throughput no yes
RICTR_HUMAN [view interactions] Low throughput no yes
PREX1_HUMAN [view entry] [view interactions] Low throughput yes no
PP2AA_HUMAN [view entry] [view interactions] Low throughput yes yes
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
CBP_HUMAN [view interactions] Low throughput no yes
ENOA_HUMAN [view entry] [view interactions] Low throughput yes yes
F110C_HUMAN [view interactions] Low throughput no yes
GCR_HUMAN [view entry] [view interactions] Low throughput yes yes
AKT2_HUMAN [view entry] [view interactions] Low throughput yes yes
ITPR1_HUMAN [view entry] [view interactions] Low throughput yes yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
CHIP_HUMAN [view entry] [view interactions] Low throughput yes yes
THOC4_HUMAN [view interactions] Low throughput no no
THEM4_HUMAN [view interactions] Low throughput no no
BECN1_HUMAN [view interactions] Low throughput no yes
PKN1_HUMAN [view entry] [view interactions] Low throughput yes yes
SKI_HUMAN [view interactions] Low throughput no yes
SIN1_HUMAN [view interactions] Low throughput no yes
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
PHLP2_HUMAN [view interactions] Low throughput no yes
CCNA2_HUMAN [view interactions] Low throughput no no
NEDD4_HUMAN [view entry] [view interactions] Low throughput yes yes
TTC3_HUMAN [view interactions] Low throughput no yes
PRKDC_HUMAN [view entry] [view interactions] Low throughput yes yes
CDC37_HUMAN [view interactions] Low throughput no yes
RPTOR_HUMAN [view interactions] Low throughput no yes
STK3_HUMAN [view interactions] Low throughput no yes
CLK2_HUMAN [view interactions] Low throughput no yes
CSK_HUMAN [view interactions] Low throughput no yes
HS90B_HUMAN [view entry] [view interactions] Low throughput yes yes
DAB2P_HUMAN [view entry] [view interactions] Low throughput yes no
HSPB1_HUMAN [view entry] [view interactions] Low throughput yes no
CYLD_HUMAN [view entry] [view interactions] Low throughput yes yes
RGCC_HUMAN [view interactions] Low throughput no yes
TRAF6_HUMAN [view entry] [view interactions] Low throughput yes yes
CNOT9_HUMAN [view interactions] Low throughput no yes
JADE1_HUMAN [view interactions] Low throughput no yes
PK3CA_HUMAN [view entry] [view interactions] Low throughput yes yes
P85A_HUMAN [view interactions] Low throughput no yes
NF2L2_HUMAN [view interactions] Low throughput no yes
TIF1A_HUMAN [view interactions] Low throughput no yes
NHRF3_HUMAN [view interactions] Low throughput no no
NCF2_HUMAN [view interactions] Low throughput no no
SIR6_HUMAN [view interactions] Low throughput no yes
FOXO4_HUMAN [view interactions] Low throughput no no
YBOX1_HUMAN [view interactions] Low throughput no yes
2ABB_HUMAN [view interactions] Low throughput no yes
CLIP3_HUMAN [view entry] [view interactions] Low throughput yes no
PKHO1_HUMAN [view interactions] Low throughput no no
BAG1_HUMAN [view interactions] Low throughput no yes
ARBK1_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCB_HUMAN [view entry] [view interactions] Low throughput yes yes
FHL1_HUMAN [view interactions] Low throughput no no
ACAP1_HUMAN [view interactions] Low throughput no yes
CDN1C_HUMAN [view interactions] Low throughput no yes
SNAI1_HUMAN [view interactions] Low throughput no yes
PP1B_HUMAN [view entry] [view interactions] Low throughput yes yes
IRF3_HUMAN [view interactions] Low throughput no yes
TBK1_HUMAN [view entry] [view interactions] Low throughput yes yes
CDN1B_HUMAN [view interactions] Low throughput no yes
NHRF1_HUMAN [view interactions] Low throughput no no
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
ACK1_HUMAN [view entry] [view interactions] Low throughput yes yes
1433S_HUMAN [view entry] [view interactions] Low throughput yes yes
TRI15_HUMAN [view interactions] Low throughput no no
RARA_HUMAN [view interactions] Low throughput no no
PYGO2_HUMAN [view interactions] Low throughput no yes
2AAA_HUMAN [view entry] [view interactions] Low throughput yes no
TRAF4_HUMAN [view interactions] Low throughput no yes
BCL10_HUMAN [view interactions] Low throughput no yes
ARRB2_HUMAN [view entry] [view interactions] Low throughput yes no
HSPB2_HUMAN [view interactions] Low throughput no yes
ARRB1_HUMAN [view entry] [view interactions] Low throughput yes yes
GABR2_HUMAN [view entry] [view interactions] Low throughput yes yes
RAF1_HUMAN [view entry] [view interactions] Low throughput yes no
RHES_HUMAN [view interactions] Low throughput no yes
PLCG1_HUMAN [view entry] [view interactions] Low throughput yes yes
IKBA_HUMAN [view interactions] Low throughput no yes
LRRK2_HUMAN [view interactions] Low throughput no yes
AGAP2_HUMAN [view entry] [view interactions] Low throughput yes yes
BRCA1_HUMAN [view interactions] Low throughput no yes
FGFR1_HUMAN [view entry] [view interactions] Low throughput yes yes
LT4R2_HUMAN [view interactions] Low throughput no no
DNMT1_HUMAN [view interactions] Low throughput no no
SRPK2_HUMAN [view entry] [view interactions] Low throughput yes yes
GLI1_HUMAN [view interactions] Low throughput no no
FANCI_HUMAN [view interactions] Low throughput no yes
KS6B1_HUMAN [view entry] [view interactions] Low throughput yes yes
FACD2_HUMAN [view interactions] Low throughput no no
PDPK1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP1_HUMAN [view interactions] Low throughput no yes
JIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
TOPB1_HUMAN [view interactions] Low throughput no yes
M3K5_HUMAN [view interactions] Low throughput no yes
UBE2S_HUMAN [view interactions] Low throughput no no
TERT_HUMAN [view interactions] Low throughput no no
CCNF_HUMAN [view interactions] Low throughput no no
KPCZ_HUMAN [view entry] [view interactions] Low throughput yes yes
KMT2D_HUMAN [view interactions] Low throughput no yes
G3P_HUMAN [view entry] [view interactions] Low throughput yes yes
ARNT_HUMAN [view entry] [view interactions] Low throughput yes yes
MDM2_HUMAN [view entry] [view interactions] Low throughput yes yes
PARVB_HUMAN [view interactions] Low throughput no no
PFKAP_HUMAN [view entry] [view interactions] Low throughput yes yes
IGF1R_HUMAN [view entry] [view interactions] Low throughput yes yes
CXA1_HUMAN [view entry] [view interactions] Low throughput yes yes
BAIP2_HUMAN [view entry] [view interactions] Low throughput yes yes
BI2L1_HUMAN [view interactions] Low throughput no yes
IL3RB_HUMAN [view interactions] Low throughput no no
IWS1_HUMAN [view interactions] Low throughput no yes
PP1A_HUMAN [view entry] [view interactions] Low throughput yes yes
AKTS1_HUMAN [view interactions] Low throughput no yes
NIBA1_HUMAN [view interactions] Low throughput no no
BIP_HUMAN [view entry] [view interactions] Low throughput yes yes
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
LMNA_HUMAN [view entry] [view interactions] Low throughput yes yes
HDAC6_HUMAN [view interactions] Low throughput no yes
RNF8_HUMAN [view interactions] Low throughput no yes
HMOX1_HUMAN [view interactions] Low throughput no no
TISB_HUMAN [view interactions] Low throughput no no
FOXO3_HUMAN [view interactions] Low throughput no yes
B2L11_HUMAN [view interactions] Low throughput no yes
PDE3A_HUMAN [view interactions] Low throughput no no
PKN2_HUMAN [view interactions] Low throughput no yes
SH3R1_HUMAN [view interactions] Low throughput no yes
PTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
TBA1A_HUMAN [view entry] [view interactions] Low throughput yes yes
BIEA_HUMAN [view interactions] Low throughput no yes
CAR11_HUMAN [view interactions] Low throughput no no
SYTL1_HUMAN [view interactions] Low throughput no yes
PDK1_HUMAN [view interactions] Low throughput no yes
TBCD7_HUMAN [view interactions] Low throughput no no
PRGC1_HUMAN [view interactions] Low throughput no no
LANC2_HUMAN [view entry] [view interactions] Low throughput yes yes
MAD1_HUMAN [view interactions] Low throughput no yes
T126B_HUMAN [view interactions] Low throughput no yes
FUBP2_HUMAN [view interactions] Low throughput no yes
GSK3A_HUMAN [view interactions] Low throughput no yes
CHFR_HUMAN [view interactions] Low throughput no no
FUS_HUMAN [view entry] [view interactions] Low throughput yes yes
FAF1_HUMAN [view interactions] Low throughput no yes
ENPL_HUMAN [view entry] [view interactions] Low throughput yes yes
SOX2_HUMAN [view interactions] Low throughput no yes
NQO1_HUMAN [view interactions] Low throughput no no
COX2_HUMAN [view entry] [view interactions] Low throughput yes yes
MK04_HUMAN [view interactions] Low throughput no no
BAP1_HUMAN [view interactions] Low throughput no yes
KDM4B_HUMAN [view interactions] Low throughput no no
WEE1_HUMAN [view interactions] Low throughput no yes
PCGF2_HUMAN [view interactions] Low throughput no no
DNM1L_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR2_HUMAN [view entry] [view interactions] Low throughput yes yes
RNF12_HUMAN [view interactions] Low throughput no yes
KAISO_HUMAN [view interactions] Low throughput no yes
DP13A_HUMAN [view entry] [view interactions] Low throughput yes yes
TCL1A_HUMAN [view interactions] Low throughput no no
H2B1B_HUMAN [view interactions] Low throughput no yes
H2B2E_HUMAN [view interactions] Low throughput no yes
TNAP3_HUMAN [view interactions] Low throughput no yes
UBP33_HUMAN [view interactions] Low throughput no yes
UHRF1_HUMAN [view interactions] Low throughput no yes
HD_HUMAN [view entry] [view interactions] Low throughput yes yes
CASP3_HUMAN [view entry] [view interactions] Low throughput yes yes
BAX_HUMAN [view interactions] Low throughput no yes
NEMO_HUMAN [view interactions] Low throughput no yes
CHSP1_HUMAN [view interactions] Low throughput no yes
MAPK2_HUMAN [view interactions] Low throughput no yes
NCOR2_HUMAN [view interactions] Low throughput no yes
KCD20_HUMAN [view interactions] Low throughput no yes
NOS3_HUMAN [view interactions] Low throughput no no
GRB10_HUMAN [view entry] [view interactions] Low throughput yes yes
XIAP_HUMAN [view interactions] Low throughput no yes
NGB_HUMAN [view interactions] Low throughput no yes
CDN1A_HUMAN [view interactions] Low throughput no no
BAD_HUMAN [view entry] [view interactions] Low throughput yes yes
PIAS2_HUMAN [view interactions] Low throughput no yes
IKKB_HUMAN [view interactions] Low throughput no yes
PCKGC_HUMAN [view interactions] Low throughput no no
IKKA_HUMAN [view interactions] Low throughput no yes
ESR1_HUMAN [view interactions] Low throughput no no
BRAF_HUMAN [view entry] [view interactions] Low throughput yes yes
B2CL1_HUMAN [view interactions] Low throughput no yes
MK14_HUMAN [view interactions] Low throughput no yes
WNK4_HUMAN [view interactions] Low throughput no yes
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
RNF11_HUMAN [view interactions] Low throughput no yes
EF2_HUMAN [view entry] [view interactions] Low throughput yes yes
RN115_HUMAN [view interactions] Low throughput no yes
ARFP2_HUMAN [view interactions] Low throughput no no
PTPA_HUMAN [view interactions] Low throughput no yes
FANCA_HUMAN [view interactions] Low throughput no no
F261_HUMAN [view interactions] Low throughput no no
IMDH2_HUMAN [view interactions] Low throughput no yes
H2B2F_HUMAN [view interactions] Low throughput no yes
K1C10_HUMAN [view interactions] Low throughput no no
H2B1C_HUMAN [view interactions] Low throughput no yes
UXS1_HUMAN [view interactions] Low throughput no yes
H2B1K_HUMAN [view interactions] Low throughput no yes
PIAS1_HUMAN [view entry] [view interactions] Low throughput yes yes
H2B1H_HUMAN [view interactions] Low throughput no yes
PHB2_HUMAN [view entry] [view interactions] Low throughput yes yes
H2B1D_HUMAN [view interactions] Low throughput no yes
GRDN_HUMAN [view interactions] Low throughput no no
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
THIC_HUMAN [view interactions] High throughput no yes
CE57L_HUMAN [view interactions] High throughput no yes
CTDS2_HUMAN [view interactions] High throughput no yes
NOL4_HUMAN [view interactions] High throughput no no
TRM2B_HUMAN [view interactions] High throughput no yes
TMCC2_HUMAN [view interactions] High throughput no yes
MTUS2_HUMAN [view interactions] High throughput no yes
PLXB1_HUMAN [view entry] [view interactions] High throughput yes yes
FETUA_HUMAN [view interactions] High throughput no no
APOH_HUMAN [view interactions] High throughput no no
PMGE_HUMAN [view interactions] High throughput no no
DNJB1_HUMAN [view entry] [view interactions] High throughput yes yes
NCOA4_HUMAN [view interactions] High throughput no no
P4K2B_HUMAN [view interactions] High throughput no yes
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
SRTD4_HUMAN [view interactions] High throughput no yes
AMRA1_HUMAN [view interactions] High throughput no yes
RL23_HUMAN [view entry] [view interactions] High throughput yes yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
RHG09_HUMAN [view interactions] High throughput no no
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
ARHGG_HUMAN [view interactions] High throughput no yes
ZHX1_HUMAN [view interactions] High throughput no no
ARG28_HUMAN [view interactions] High throughput no yes
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
FBW1A_HUMAN [view interactions] High throughput no yes
REX1B_HUMAN [view interactions] High throughput no no
CA174_HUMAN [view interactions] High throughput no yes
CGBP1_HUMAN [view interactions] High throughput no yes
CKLF8_HUMAN [view interactions] High throughput no yes
CNKR3_HUMAN [view interactions] High throughput no yes
CTDP1_HUMAN [view interactions] High throughput no yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
EFHC1_HUMAN [view interactions] High throughput no yes
F168A_HUMAN [view interactions] High throughput no yes
ABRX1_HUMAN [view interactions] High throughput no no
FRDA_HUMAN [view interactions] High throughput no yes
GAB1_HUMAN [view interactions] High throughput no yes
GMPPA_HUMAN [view interactions] High throughput no no
NSF_HUMAN [view entry] [view interactions] High throughput yes yes
ALAT2_HUMAN [view interactions] High throughput no yes
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
HEAT3_HUMAN [view interactions] High throughput no yes
ISCA2_HUMAN [view interactions] High throughput no yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
IP3KB_HUMAN [view interactions] High throughput no no
HXK1_HUMAN [view entry] [view interactions] High throughput yes yes
NKG2A_HUMAN [view interactions] High throughput no no
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
MAGB1_HUMAN [view interactions] High throughput no no
TBB5_HUMAN [view interactions] High throughput no yes
MARK4_HUMAN [view interactions] High throughput no yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
MEF2D_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
MLF2_HUMAN [view entry] [view interactions] High throughput yes yes
MOK_HUMAN [view interactions] High throughput no no
PEBP1_HUMAN [view entry] [view interactions] High throughput yes yes
NED4L_HUMAN [view entry] [view interactions] High throughput yes yes
MDHC_HUMAN [view entry] [view interactions] High throughput yes yes
NKD1_HUMAN [view interactions] High throughput no no
COT2_HUMAN [view interactions] High throughput no no
LDHA_HUMAN [view entry] [view interactions] High throughput yes yes
NRIP2_HUMAN [view interactions] High throughput no yes
HBB_HUMAN [view interactions] High throughput no no
OSB11_HUMAN [view interactions] High throughput no no
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
OXSR1_HUMAN [view interactions] High throughput no yes
ALDOA_HUMAN [view entry] [view interactions] High throughput yes no
RPP29_HUMAN [view entry] [view interactions] High throughput yes yes
IF4A1_HUMAN [view interactions] High throughput no no
POP7_HUMAN [view interactions] High throughput no yes
PSB4_HUMAN [view interactions] High throughput no yes
PP1RB_HUMAN [view interactions] High throughput no yes
GUAD_HUMAN [view entry] [view interactions] High throughput yes yes
KAP0_HUMAN [view entry] [view interactions] High throughput yes yes
VPP2_HUMAN [view interactions] High throughput no yes
PSRC1_HUMAN [view interactions] High throughput no no
P5CR3_HUMAN [view interactions] High throughput no no
GDS1_HUMAN [view entry] [view interactions] High throughput yes yes
PINK1_HUMAN [view interactions] High throughput no yes
REPS1_HUMAN [view interactions] High throughput no yes
RUVB2_HUMAN [view interactions] High throughput no yes
SMBT2_HUMAN [view interactions] High throughput no yes
SHAN2_HUMAN [view entry] [view interactions] High throughput yes yes
RCN2_HUMAN [view interactions] High throughput no yes
FCERB_HUMAN [view interactions] High throughput no no
SHQ1_HUMAN [view interactions] High throughput no no
S25A3_HUMAN [view entry] [view interactions] High throughput yes no
SLFN5_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
SRBS1_HUMAN [view entry] [view interactions] High throughput yes yes
HSP76_HUMAN [view entry] [view interactions] High throughput yes yes
SPT33_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
IGSF8_HUMAN [view entry] [view interactions] High throughput yes no
STOX1_HUMAN [view interactions] High throughput no yes
H90B3_HUMAN [view interactions] High throughput no no
CD81_HUMAN [view interactions] High throughput no no
TBCE_HUMAN [view interactions] High throughput no no
RMP_HUMAN [view interactions] High throughput no yes
UBP50_HUMAN [view entry] [view interactions] High throughput yes no
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
WDR53_HUMAN [view interactions] High throughput no yes
RL1D1_HUMAN [view interactions] High throughput no yes
ZCCHV_HUMAN [view interactions] High throughput no yes
NOP56_HUMAN [view interactions] High throughput no yes
PPM1H_HUMAN [view interactions] High throughput no yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
SPN90_HUMAN [view entry] [view interactions] High throughput yes no
DSG1_HUMAN [view entry] [view interactions] High throughput yes no
OFD1_HUMAN [view interactions] High throughput no yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
MOD5_HUMAN [view interactions] High throughput no yes
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
CD44_HUMAN [view entry] [view interactions] High throughput yes yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
CDK4_HUMAN [view interactions] High throughput no no
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
CDK6_HUMAN [view interactions] High throughput no yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
CDN2B_HUMAN [view interactions] High throughput no no
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
CDN2C_HUMAN [view interactions] High throughput no yes
DESP_HUMAN [view entry] [view interactions] High throughput yes no
EPHA2_HUMAN [view interactions] High throughput no no
AXA2L_HUMAN [view interactions] High throughput no no
FGFR4_HUMAN [view interactions] High throughput no no
ANXA2_HUMAN [view entry] [view interactions] High throughput yes no
GLIS2_HUMAN [view interactions] High throughput no no
LATS2_HUMAN [view interactions] High throughput no yes
MPRI_HUMAN [view interactions] High throughput no yes
MP2K3_HUMAN [view entry] [view interactions] High throughput yes yes
CYTB_HUMAN [view interactions] High throughput no no
MP2K5_HUMAN [view interactions] High throughput no yes
SPRR3_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
CRNN_HUMAN [view interactions] High throughput no no
PGFRA_HUMAN [view interactions] High throughput no no
K1H2_HUMAN [view interactions] High throughput no no
RASF1_HUMAN [view interactions] High throughput no yes
S10A3_HUMAN [view interactions] High throughput no no
ARAF_HUMAN [view interactions] High throughput no yes
CBLC_HUMAN [view interactions] High throughput no yes
CCND2_HUMAN [view interactions] High throughput no yes
KPCE_HUMAN [view entry] [view interactions] High throughput yes yes
TCOF_HUMAN [view interactions] High throughput no yes
CCNE1_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
HIF1A_HUMAN [view interactions] High throughput no no
KAT2A_HUMAN [view interactions] High throughput no no
AHSA1_HUMAN [view entry] [view interactions] High throughput yes yes
ERD22_HUMAN [view interactions] High throughput no yes
MP2K6_HUMAN [view interactions] High throughput no yes
NF1_HUMAN [view entry] [view interactions] High throughput yes no
SOX4_HUMAN [view interactions] High throughput no yes
TEAD2_HUMAN [view interactions] High throughput no no
TNR1A_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
DS13A_HUMAN [view interactions] High throughput no no
TIE2_HUMAN [view interactions] High throughput no no
TE2IP_HUMAN [view interactions] High throughput no yes
AKT3_HUMAN [view interactions] High throughput no yes
FAK1_HUMAN [view entry] [view interactions] High throughput yes yes
RBBP5_HUMAN [view interactions] High throughput no yes
SL9A1_HUMAN [view interactions] High throughput no no
PK3CB_HUMAN [view interactions] High throughput no yes
SGT1_HUMAN [view interactions] High throughput no no
RPE_HUMAN [view interactions] High throughput no yes
PDK2_HUMAN [view interactions] High throughput no yes
KKCC1_HUMAN [view entry] [view interactions] High throughput yes yes
BRE1B_HUMAN [view interactions] High throughput no yes
EGLN1_HUMAN [view entry] [view interactions] High throughput yes yes
LA_HUMAN [view interactions] High throughput no yes
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
BRE1A_HUMAN [view interactions] High throughput no yes
EFL1_HUMAN [view interactions] High throughput no yes
WDR48_HUMAN [view entry] [view interactions] High throughput yes yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
CUL1_HUMAN [view interactions] High throughput no yes
TRM61_HUMAN [view interactions] High throughput no no
RFA1_HUMAN [view interactions] High throughput no yes
TRHDE_HUMAN [view interactions] High throughput no no
RFA2_HUMAN [view interactions] High throughput no yes
TBB4B_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
TPM4_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
TPM2_HUMAN [view entry] [view interactions] High throughput yes yes
M4K4_HUMAN [view interactions] High throughput no yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
CD2AP_HUMAN [view interactions] High throughput no no
INSR_HUMAN [view interactions] High throughput no yes
UCK2_HUMAN [view interactions] High throughput no no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
KCC2D_HUMAN [view entry] [view interactions] High throughput yes yes
FLII_HUMAN [view entry] [view interactions] High throughput yes yes
PKD2_HUMAN [view interactions] High throughput no yes
INT3_HUMAN [view interactions] High throughput no yes
CAN1_HUMAN [view entry] [view interactions] High throughput yes yes
CABL1_HUMAN [view interactions] High throughput no no
ATRX_HUMAN [view entry] [view interactions] High throughput yes yes
E2AK3_HUMAN [view interactions] High throughput no yes
PKD1_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
SHPS1_HUMAN [view entry] [view interactions] High throughput yes yes
BUB1_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
FBXW7_HUMAN [view interactions] High throughput no yes
ZDH18_HUMAN [view interactions] High throughput no yes
MLH3_HUMAN [view interactions] High throughput no no
ZDH23_HUMAN [view interactions] High throughput no no
MSH2_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
RASN_HUMAN [view entry] [view interactions] High throughput yes no
PMS2_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
STK11_HUMAN [view interactions] High throughput no yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
TLR2_HUMAN [view interactions] High throughput no no
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
SOAT2_HUMAN [view interactions] High throughput no no
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
GET4_HUMAN [view interactions] High throughput no yes
UBR5_HUMAN [view interactions] High throughput no no
CLAP2_HUMAN [view entry] [view interactions] High throughput yes no
CCNI_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
ENOG_HUMAN [view entry] [view interactions] High throughput yes yes
FNDC5_HUMAN [view interactions] High throughput no no
GFAP_HUMAN [view entry] [view interactions] High throughput yes no
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
RIGI_HUMAN [view interactions] High throughput no yes
NMDE1_HUMAN [view entry] [view interactions] High throughput yes yes
FZR1_HUMAN [view interactions] High throughput no no
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
PRS8_HUMAN [view interactions] High throughput no yes
SOSD1_HUMAN [view interactions] High throughput no no
MYPR_HUMAN [view entry] [view interactions] High throughput yes yes
PTN3_HUMAN [view interactions] High throughput no yes
RNF14_HUMAN [view interactions] High throughput no yes
PTGDS_HUMAN [view interactions] High throughput no yes
UMPS_HUMAN [view interactions] High throughput no no
SRR_HUMAN [view entry] [view interactions] High throughput yes yes
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
SYUB_HUMAN [view interactions] High throughput no yes
EFMT3_HUMAN [view interactions] High throughput no no
ST4A1_HUMAN [view interactions] High throughput no yes
SRB4D_HUMAN [view interactions] High throughput no no
ZN691_HUMAN [view interactions] High throughput no yes
PDE3B_HUMAN [view interactions] High throughput no no
UCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
ABH15_HUMAN [view interactions] High throughput no yes
CASC3_HUMAN [view interactions] High throughput no yes
AGR3_HUMAN [view interactions] High throughput no no
I13R2_HUMAN [view interactions] High throughput no no
IL24_HUMAN [view interactions] High throughput no no
ESIP1_HUMAN [view interactions] High throughput no yes
VASP_HUMAN [view entry] [view interactions] High throughput yes yes
MRC2_HUMAN [view interactions] High throughput no yes
KS6B2_HUMAN [view interactions] High throughput no yes
MTA3_HUMAN [view interactions] High throughput no yes
GEPH_HUMAN [view entry] [view interactions] High throughput yes yes
OSGI1_HUMAN [view interactions] High throughput no no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
RSLAB_HUMAN [view interactions] High throughput no no
S10AE_HUMAN [view interactions] High throughput no no
SPB5_HUMAN [view interactions] High throughput no no
ST14_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
TFF1_HUMAN [view interactions] High throughput no no
THRSP_HUMAN [view interactions] High throughput no no
PARPT_HUMAN [view interactions] High throughput no no
NSD3_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
H2B3B_HUMAN [view interactions] High throughput no yes
CEP76_HUMAN [view interactions] High throughput no yes
H2B1J_HUMAN [view interactions] High throughput no yes
DDT4L_HUMAN [view interactions] High throughput no no
H2B1O_HUMAN [view interactions] High throughput no yes
MESD_HUMAN [view interactions] High throughput no yes
XAF1_HUMAN [view interactions] High throughput no yes
PREB_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
SRSF5_HUMAN [view interactions] High throughput no yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
YIF1B_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
TOP3B_HUMAN [view interactions] High throughput no no
THIO_HUMAN [view interactions] High throughput no yes
ZNF24_HUMAN [view interactions] High throughput no yes
PLK1_HUMAN [view interactions] High throughput no yes
CYH1_HUMAN [view interactions] High throughput no no
PRUN2_HUMAN [view entry] [view interactions] High throughput yes yes
GALA_HUMAN [view interactions] High throughput no no
SIK1_HUMAN [view interactions] High throughput no yes
BTBD1_HUMAN [view interactions] High throughput no yes
CHK1_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
KS6A3_HUMAN [view entry] [view interactions] High throughput yes yes
NLGN3_HUMAN [view entry] [view interactions] High throughput yes yes
KS6A1_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
SGK2_HUMAN [view interactions] High throughput no yes
KS6A4_HUMAN [view interactions] High throughput no yes
PPM1A_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
4EBP1_HUMAN [view entry] [view interactions] High throughput yes yes
PTN11_HUMAN [view entry] [view interactions] High throughput yes yes
MATK_HUMAN [view interactions] High throughput no yes
SPT6H_HUMAN [view interactions] High throughput no yes