Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CTNA1_HUMAN

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. Involved in the regulation of WWTR1/TAZ, YAP1 and TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation . May play a crucial role in cell differentiation. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in CTNA1_HUMAN
GO:0017076 purine nucleotide binding 35.5072 4 no
GO:0032555 purine ribonucleotide binding 35.5072 4 no
GO:0035639 purine ribonucleoside triphosphate binding 35.5072 4 no
GO:0019900 kinase binding 28.9855 4 no
GO:0019901 protein kinase binding 28.9855 5 no
GO:0045296 cadherin binding 23.1884 4 yes
GO:0005524 ATP binding 23.1884 5 no
GO:0030554 adenyl nucleotide binding 23.1884 5 no
GO:0032559 adenyl ribonucleotide binding 23.1884 5 no
GO:0003779 actin binding 16.6667 4 yes
GO:0003723 RNA binding 10.1449 4 yes
GO:0017166 vinculin binding 3.6232 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CTNA1_HUMAN
GO:0048522 positive regulation of cellular process 69.5652 4 yes
GO:0010646 regulation of cell communication 61.5942 4 yes
GO:0048523 negative regulation of cellular process 57.9710 4 yes
GO:0009966 regulation of signal transduction 57.2464 4 yes
GO:0051128 regulation of cellular component organization 54.3478 4 no
GO:0060255 regulation of macromolecule metabolic process 52.1739 4 no
GO:0031323 regulation of cellular metabolic process 48.5507 4 no
GO:0009893 positive regulation of metabolic process 47.1014 4 no
GO:0080090 regulation of primary metabolic process 46.3768 4 no
GO:0010604 positive regulation of macromolecule metabolic process 46.3768 5 no
GO:0051171 regulation of nitrogen compound metabolic process 45.6522 4 no
GO:0022607 cellular component assembly 43.4783 4 yes
GO:0048584 positive regulation of response to stimulus 42.7536 4 yes
GO:0008104 protein localization 42.0290 4 yes
GO:1902531 regulation of intracellular signal transduction 41.3043 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 40.5797 5 no
GO:0010647 positive regulation of cell communication 39.8551 5 yes
GO:0023056 positive regulation of signaling 39.8551 4 yes
GO:0006996 organelle organization 39.8551 4 no
GO:0051049 regulation of transport 38.4058 4 no
GO:0031325 positive regulation of cellular metabolic process 38.4058 5 no
GO:0009967 positive regulation of signal transduction 36.9565 5 yes
GO:0051246 regulation of protein metabolic process 36.9565 5 no
GO:0010468 regulation of gene expression 36.2319 5 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0051130 positive regulation of cellular component organization 32.6087 5 no
GO:0030030 cell projection organization 32.6087 4 yes
GO:0071310 cellular response to organic substance 32.6087 4 yes
GO:0044087 regulation of cellular component biogenesis 31.8841 4 no
GO:0042127 regulation of cell population proliferation 31.8841 4 yes
GO:0031399 regulation of protein modification process 31.8841 6 no
GO:0007010 cytoskeleton organization 31.1594 5 no
GO:0033043 regulation of organelle organization 31.1594 5 no
GO:0051174 regulation of phosphorus metabolic process 30.4348 5 no
GO:0031344 regulation of cell projection organization 30.4348 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 30.4348 6 no
GO:0009889 regulation of biosynthetic process 30.4348 4 no
GO:0019220 regulation of phosphate metabolic process 30.4348 6 no
GO:0051240 positive regulation of multicellular organismal process 29.7101 4 no
GO:0010941 regulation of cell death 29.7101 4 yes
GO:0034330 cell junction organization 29.7101 4 yes
GO:0045595 regulation of cell differentiation 29.7101 4 yes
GO:2000145 regulation of cell motility 29.7101 4 yes
GO:0031326 regulation of cellular biosynthetic process 29.7101 5 no
GO:0051094 positive regulation of developmental process 28.9855 4 no
GO:0048585 negative regulation of response to stimulus 28.9855 4 yes
GO:0060341 regulation of cellular localization 28.9855 4 yes
GO:0009892 negative regulation of metabolic process 28.9855 4 no
GO:0030155 regulation of cell adhesion 28.9855 4 no
GO:0042325 regulation of phosphorylation 28.9855 7 no
GO:0010648 negative regulation of cell communication 28.2609 5 yes
GO:0023057 negative regulation of signaling 28.2609 4 yes
GO:0032880 regulation of protein localization 28.2609 5 yes
GO:0042981 regulation of apoptotic process 28.2609 6 yes
GO:0043067 regulation of programmed cell death 28.2609 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 28.2609 5 no
GO:0030334 regulation of cell migration 28.2609 5 no
GO:0043085 positive regulation of catalytic activity 27.5362 4 no
GO:0001932 regulation of protein phosphorylation 27.5362 7 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 27.5362 5 no
GO:0022603 regulation of anatomical structure morphogenesis 26.8116 4 no
GO:0051050 positive regulation of transport 26.8116 4 no
GO:0010605 negative regulation of macromolecule metabolic process 26.8116 5 no
GO:0031401 positive regulation of protein modification process 26.8116 7 no
GO:0045937 positive regulation of phosphate metabolic process 26.0870 7 no
GO:1902533 positive regulation of intracellular signal transduction 26.0870 6 no
GO:0120036 plasma membrane bounded cell projection organization 26.0870 5 yes
GO:1901701 cellular response to oxygen-containing compound 26.0870 4 yes
GO:0010562 positive regulation of phosphorus metabolic process 26.0870 6 no
GO:0043412 macromolecule modification 25.3623 4 no
GO:0009968 negative regulation of signal transduction 25.3623 5 yes
GO:0042327 positive regulation of phosphorylation 25.3623 8 no
GO:0036211 protein modification process 24.6377 4 no
GO:0006796 phosphate-containing compound metabolic process 24.6377 4 no
GO:0010243 response to organonitrogen compound 24.6377 4 yes
GO:2000026 regulation of multicellular organismal development 24.6377 4 yes
GO:0071702 organic substance transport 24.6377 4 no
GO:0051252 regulation of RNA metabolic process 23.9130 5 no
GO:0001934 positive regulation of protein phosphorylation 23.9130 8 no
GO:0031324 negative regulation of cellular metabolic process 23.9130 5 no
GO:0043408 regulation of MAPK cascade 23.1884 6 no
GO:1903506 regulation of nucleic acid-templated transcription 23.1884 7 no
GO:2001141 regulation of RNA biosynthetic process 23.1884 6 no
GO:0080134 regulation of response to stress 22.4638 4 no
GO:0051336 regulation of hydrolase activity 22.4638 4 no
GO:0071705 nitrogen compound transport 22.4638 4 no
GO:0006355 regulation of DNA-templated transcription 22.4638 6 no
GO:0045597 positive regulation of cell differentiation 21.7391 5 no
GO:0016192 vesicle-mediated transport 21.7391 4 no
GO:0051493 regulation of cytoskeleton organization 21.7391 6 no
GO:0051172 negative regulation of nitrogen compound metabolic process 21.0145 5 no
GO:0051338 regulation of transferase activity 21.0145 4 no
GO:0034329 cell junction assembly 21.0145 5 yes
GO:0045216 cell-cell junction organization 21.0145 5 yes
GO:0060284 regulation of cell development 21.0145 5 yes
GO:1901699 cellular response to nitrogen compound 21.0145 4 yes
GO:0008284 positive regulation of cell population proliferation 21.0145 5 no
GO:0051129 negative regulation of cellular component organization 20.2899 5 no
GO:0032970 regulation of actin filament-based process 20.2899 4 no
GO:0010975 regulation of neuron projection development 20.2899 7 no
GO:0071417 cellular response to organonitrogen compound 20.2899 4 yes
GO:0009891 positive regulation of biosynthetic process 20.2899 5 no
GO:0010628 positive regulation of gene expression 20.2899 6 no
GO:0097435 supramolecular fiber organization 19.5652 4 yes
GO:0060548 negative regulation of cell death 18.8406 5 yes
GO:0007015 actin filament organization 16.6667 5 yes
GO:0010942 positive regulation of cell death 16.6667 5 yes
GO:0014070 response to organic cyclic compound 16.6667 4 yes
GO:0031175 neuron projection development 16.6667 6 yes
GO:0043066 negative regulation of apoptotic process 16.6667 7 yes
GO:0043069 negative regulation of programmed cell death 16.6667 6 yes
GO:0051241 negative regulation of multicellular organismal process 16.6667 4 yes
GO:0051960 regulation of nervous system development 16.6667 5 yes
GO:0043065 positive regulation of apoptotic process 15.2174 7 yes
GO:0043068 positive regulation of programmed cell death 15.2174 6 yes
GO:0007043 cell-cell junction assembly 13.7681 6 yes
GO:0050767 regulation of neurogenesis 13.7681 6 yes
GO:0071407 cellular response to organic cyclic compound 13.7681 5 yes
GO:0008285 negative regulation of cell population proliferation 13.0435 5 yes
GO:0051093 negative regulation of developmental process 13.0435 4 yes
GO:0045596 negative regulation of cell differentiation 12.3188 5 yes
GO:0040013 negative regulation of locomotion 10.8696 4 yes
GO:2000146 negative regulation of cell motility 10.8696 5 yes
GO:2001233 regulation of apoptotic signaling pathway 10.8696 5 yes
GO:2001234 negative regulation of apoptotic signaling pathway 8.6957 6 yes
GO:0010721 negative regulation of cell development 7.9710 6 yes
GO:1900180 regulation of protein localization to nucleus 7.2464 6 yes
GO:2001236 regulation of extrinsic apoptotic signaling pathway 7.2464 6 yes
GO:0097305 response to alcohol 6.5217 4 yes
GO:2000177 regulation of neural precursor cell proliferation 6.5217 5 yes
GO:0050768 negative regulation of neurogenesis 5.7971 6 yes
GO:0051961 negative regulation of nervous system development 5.7971 5 yes
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 5.7971 7 yes
GO:1903828 negative regulation of protein localization 5.0725 5 yes
GO:0097306 cellular response to alcohol 4.3478 5 yes
GO:0042476 odontogenesis 3.6232 4 yes
GO:0071680 response to indole-3-methanol 3.6232 5 yes
GO:0071681 cellular response to indole-3-methanol 3.6232 5 yes
GO:0008589 regulation of smoothened signaling pathway 2.8986 5 yes
GO:0043297 apical junction assembly 2.8986 7 yes
GO:0048678 response to axon injury 2.8986 4 yes
GO:0090136 epithelial cell-cell adhesion 2.8986 4 yes
GO:1900181 negative regulation of protein localization to nucleus 2.8986 6 yes
GO:1902692 regulation of neuroblast proliferation 2.8986 6 yes
GO:2001235 positive regulation of apoptotic signaling pathway 2.8986 6 yes
GO:0008406 gonad development 2.1739 4 yes
GO:0008584 male gonad development 2.1739 5 yes
GO:0016264 gap junction assembly 2.1739 7 yes
GO:0042475 odontogenesis of dentin-containing tooth 2.1739 5 yes
GO:0045880 positive regulation of smoothened signaling pathway 2.1739 6 yes
GO:1901099 negative regulation of signal transduction in absence of ligand 2.1739 6 yes
GO:2000178 negative regulation of neural precursor cell proliferation 2.1739 6 yes
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 2.1739 7 yes
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 2.1739 7 yes
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 2.1739 7 yes
GO:0007406 negative regulation of neuroblast proliferation 1.4493 7 yes
GO:0031102 neuron projection regeneration 1.4493 4 yes
GO:0031103 axon regeneration 1.4493 5 yes
GO:0043627 response to estrogen 1.4493 4 yes
GO:0061564 axon development 1.4493 7 yes
GO:2001044 regulation of integrin-mediated signaling pathway 1.4493 5 yes
GO:2001045 negative regulation of integrin-mediated signaling pathway 1.4493 6 yes
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 1.4493 8 yes

Disease

Term Name % Distance from top the of the tree Annotated in CTNA1_HUMAN
DOID:0050700 cardiomyopathy 2.1739 4 no
DOID:0060036 intrinsic cardiomyopathy 2.1739 5 no
DOID:114 heart disease 2.1739 3 no
DOID:0060038 specific developmental disorder 1.4493 3 no
DOID:1059 intellectual disability 1.4493 4 no
DOID:0111962 combined immunodeficiency 1.4493 4 no
DOID:612 primary immunodeficiency disease 1.4493 3 no
DOID:0050686 organ system cancer 1.4493 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ZO2_HUMAN [view entry] [view interactions] Low throughput yes no
SPTB2_HUMAN [view entry] [view interactions] Low throughput yes yes
AFAD_HUMAN [view interactions] Low throughput no yes
CE350_HUMAN [view interactions] Low throughput no yes
ARMC8_HUMAN [view interactions] Low throughput no yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PLAK_HUMAN [view entry] [view interactions] Low throughput yes yes
APC_HUMAN [view entry] [view interactions] Low throughput yes no
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
VINC_HUMAN [view entry] [view interactions] Low throughput yes no
ECT2_HUMAN [view interactions] Low throughput no no
RGAP1_HUMAN [view interactions] Low throughput no no
IKBA_HUMAN [view interactions] Low throughput no yes
BCL9L_HUMAN [view interactions] Low throughput no no
BCL9_HUMAN [view interactions] Low throughput no yes
CADH5_HUMAN [view interactions] Low throughput no yes
PARD3_HUMAN [view interactions] Low throughput no yes
YAP1_HUMAN [view interactions] Low throughput no yes
LIMA1_HUMAN [view entry] [view interactions] Low throughput yes no
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
CTNA1_HUMAN [view entry] [view interactions] Low throughput yes yes
OBI1_HUMAN [view interactions] Low throughput no yes
ACTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
LRAT2_HUMAN [view interactions] Low throughput no yes
IQEC1_HUMAN [view entry] [view interactions] Low throughput yes yes
B2MG_HUMAN [view interactions] Low throughput no yes
CTND1_HUMAN [view entry] [view interactions] Low throughput yes no
CADH3_HUMAN [view interactions] Low throughput no no
CADH2_HUMAN [view entry] [view interactions] Low throughput yes no
CAH9_HUMAN [view interactions] Low throughput no no
PTN14_HUMAN [view interactions] Low throughput no yes
VEZA_HUMAN [view interactions] Low throughput no yes
MYO7A_HUMAN [view interactions] Low throughput no yes
PSN1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG1_HUMAN [view entry] [view interactions] Low throughput yes yes
FMN1_HUMAN [view interactions] Low throughput no no
NUMB_HUMAN [view entry] [view interactions] Low throughput yes yes
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOC_HUMAN [view interactions] High throughput no no
RHOD_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RANG_HUMAN [view interactions] High throughput no no
TBB4B_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
UBC9_HUMAN [view interactions] High throughput no yes
GARS_HUMAN [view interactions] High throughput no yes
OSBP1_HUMAN [view interactions] High throughput no yes
SC23A_HUMAN [view entry] [view interactions] High throughput yes yes
UBP11_HUMAN [view interactions] High throughput no yes
XRCC6_HUMAN [view interactions] High throughput no yes
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
CUL2_HUMAN [view interactions] High throughput no yes
IF4B_HUMAN [view entry] [view interactions] High throughput yes yes
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
ANM3_HUMAN [view interactions] High throughput no yes
XPO7_HUMAN [view entry] [view interactions] High throughput yes yes
CATL1_HUMAN [view interactions] High throughput no yes
SDCB1_HUMAN [view entry] [view interactions] High throughput yes yes
ZO1_HUMAN [view entry] [view interactions] High throughput yes no
AGR2_HUMAN [view interactions] High throughput no no
DPPA3_HUMAN [view interactions] High throughput no no
DNJC5_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
ANK3_HUMAN [view entry] [view interactions] High throughput yes yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
ANR26_HUMAN [view interactions] High throughput no yes
RHG32_HUMAN [view entry] [view interactions] High throughput yes yes
CC85C_HUMAN [view interactions] High throughput no yes
GRDN_HUMAN [view interactions] High throughput no no
DAPLE_HUMAN [view interactions] High throughput no yes
CENPF_HUMAN [view interactions] High throughput no no
CING_HUMAN [view interactions] High throughput no no
CLMN_HUMAN [view entry] [view interactions] High throughput yes no
DLG5_HUMAN [view entry] [view interactions] High throughput yes no
DSG2_HUMAN [view interactions] High throughput no no
ERBIN_HUMAN [view entry] [view interactions] High throughput yes yes
F110B_HUMAN [view interactions] High throughput no yes
JCAD_HUMAN [view interactions] High throughput no yes
SKT_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
LZTS2_HUMAN [view interactions] High throughput no no
MAGD2_HUMAN [view interactions] High throughput no yes
MAGI1_HUMAN [view interactions] High throughput no no
NDUF4_HUMAN [view interactions] High throughput no yes
NHS_HUMAN [view interactions] High throughput no yes
PKP2_HUMAN [view interactions] High throughput no yes
PKP4_HUMAN [view entry] [view interactions] High throughput yes yes
PLCH1_HUMAN [view interactions] High throughput no no
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA6_HUMAN [view entry] [view interactions] High throughput yes no
ASPP1_HUMAN [view interactions] High throughput no yes
GDS1_HUMAN [view entry] [view interactions] High throughput yes yes
RINT1_HUMAN [view interactions] High throughput no yes
SCRIB_HUMAN [view entry] [view interactions] High throughput yes no
SI1L3_HUMAN [view interactions] High throughput no yes
SIR2_HUMAN [view entry] [view interactions] High throughput yes yes
SRBS1_HUMAN [view entry] [view interactions] High throughput yes yes
SRBS2_HUMAN [view entry] [view interactions] High throughput yes no
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
ASPP2_HUMAN [view interactions] High throughput no yes
AFG32_HUMAN [view entry] [view interactions] High throughput yes yes
ANR28_HUMAN [view interactions] High throughput no no
BCR_HUMAN [view entry] [view interactions] High throughput yes yes
CP131_HUMAN [view interactions] High throughput no no
DTNA_HUMAN [view entry] [view interactions] High throughput yes yes
DVL1_HUMAN [view entry] [view interactions] High throughput yes yes
ECD_HUMAN [view interactions] High throughput no yes
IKKB_HUMAN [view interactions] High throughput no yes
K1671_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
KDIS_HUMAN [view interactions] High throughput no yes
LIMD1_HUMAN [view interactions] High throughput no yes
MTR1A_HUMAN [view interactions] High throughput no no
LMO7_HUMAN [view entry] [view interactions] High throughput yes yes
MTR1B_HUMAN [view interactions] High throughput no yes
LRC49_HUMAN [view interactions] High throughput no no
MACF1_HUMAN [view entry] [view interactions] High throughput yes yes
M4K4_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
MARK3_HUMAN [view interactions] High throughput no yes
ARRB2_HUMAN [view entry] [view interactions] High throughput yes no
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
NEBL_HUMAN [view entry] [view interactions] High throughput yes no
PEAK1_HUMAN [view interactions] High throughput no yes
ARAF_HUMAN [view interactions] High throughput no yes
PHAR4_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
RASF8_HUMAN [view interactions] High throughput no yes
BMR1A_HUMAN [view interactions] High throughput no no
ENTR1_HUMAN [view interactions] High throughput no no
SI1L1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
AXIN1_HUMAN [view interactions] High throughput no yes
UTRN_HUMAN [view entry] [view interactions] High throughput yes yes
FBW1B_HUMAN [view interactions] High throughput no yes
E41LA_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
NHSL1_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
CETN2_HUMAN [view interactions] High throughput no yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
GSK3A_HUMAN [view interactions] High throughput no yes
LYN_HUMAN [view entry] [view interactions] High throughput yes no
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
NU155_HUMAN [view interactions] High throughput no yes
TGFR1_HUMAN [view interactions] High throughput no no
OCLN_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
LRRK2_HUMAN [view interactions] High throughput no yes
ZYX_HUMAN [view interactions] High throughput no no
DUS4_HUMAN [view entry] [view interactions] High throughput yes no
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
CSK_HUMAN [view interactions] High throughput no yes
NLGN2_HUMAN [view entry] [view interactions] High throughput yes yes
MP2K3_HUMAN [view entry] [view interactions] High throughput yes yes
GRB10_HUMAN [view entry] [view interactions] High throughput yes yes
RHG21_HUMAN [view entry] [view interactions] High throughput yes yes
RHG23_HUMAN [view entry] [view interactions] High throughput yes yes
ECT2L_HUMAN [view interactions] High throughput no no
ZBT18_HUMAN [view interactions] High throughput no yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
E2F3_HUMAN [view interactions] High throughput no no
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP1_HUMAN [view interactions] High throughput no yes
TF7L2_HUMAN [view interactions] High throughput no yes
DDR2_HUMAN [view interactions] High throughput no no
MET_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
TYRO3_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
MCM7_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
PKHA7_HUMAN [view interactions] High throughput no yes
ANGI_HUMAN [view interactions] High throughput no no
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
PEX5R_HUMAN [view entry] [view interactions] High throughput yes yes
RYR2_HUMAN [view entry] [view interactions] High throughput yes yes
LITD1_HUMAN [view interactions] High throughput no no
INSR_HUMAN [view interactions] High throughput no yes
CD81_HUMAN [view interactions] High throughput no no
AKT1_HUMAN [view entry] [view interactions] High throughput yes yes
BAAT_HUMAN [view interactions] High throughput no no
ALDOB_HUMAN [view interactions] High throughput no no
CATL2_HUMAN [view interactions] High throughput no yes
F16P1_HUMAN [view interactions] High throughput no no
F16P2_HUMAN [view interactions] High throughput no no
FRAT2_HUMAN [view interactions] High throughput no no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
DHB3_HUMAN [view interactions] High throughput no no
MP2K1_HUMAN [view entry] [view interactions] High throughput yes yes
CC180_HUMAN [view interactions] High throughput no no
SIAS_HUMAN [view interactions] High throughput no yes
SFRP2_HUMAN [view interactions] High throughput no no
SFRP4_HUMAN [view interactions] High throughput no no
SMAD1_HUMAN [view interactions] High throughput no yes
STX17_HUMAN [view interactions] High throughput no yes
TDRD7_HUMAN [view interactions] High throughput no yes
ZN189_HUMAN [view interactions] High throughput no yes
ZN510_HUMAN [view interactions] High throughput no yes
ZGPAT_HUMAN [view interactions] High throughput no no
PAR2_HUMAN [view entry] [view interactions] High throughput yes yes
CSN5_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
NHRF2_HUMAN [view entry] [view interactions] High throughput yes no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
CTDSL_HUMAN [view interactions] High throughput no no
EPHA4_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA7_HUMAN [view entry] [view interactions] High throughput yes no
FGFR1_HUMAN [view interactions] High throughput no yes
SASH1_HUMAN [view interactions] High throughput no yes
4ET_HUMAN [view interactions] High throughput no yes
RBM26_HUMAN [view interactions] High throughput no yes
PTPRQ_HUMAN [view interactions] High throughput no no
PCP2_HUMAN [view interactions] High throughput no no
RYK_HUMAN [view interactions] High throughput no no
SIR7_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
CTNA3_HUMAN [view interactions] High throughput no no
OBSL1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
FBW1A_HUMAN [view interactions] High throughput no yes
UNK_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
HERC2_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
CAF1A_HUMAN [view interactions] High throughput no yes
CF298_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
CADH8_HUMAN [view interactions] High throughput no no
CNBP1_HUMAN [view interactions] High throughput no no
DMD_HUMAN [view entry] [view interactions] High throughput yes no
SAPC1_HUMAN [view interactions] High throughput no no
SLAF7_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
UBE2A_HUMAN [view interactions] High throughput no no
BRCA1_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
EGLN3_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
SUZ12_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
TISD_HUMAN [view interactions] High throughput no no
CDK9_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
DUS10_HUMAN [view entry] [view interactions] High throughput yes yes
PTPRU_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
CUL7_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
WDR76_HUMAN [view interactions] High throughput no no
INSI1_HUMAN [view interactions] High throughput no no
ANDR_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
CAD12_HUMAN [view interactions] High throughput no no
TX1B3_HUMAN [view interactions] High throughput no no
CTNA2_HUMAN [view entry] [view interactions] High throughput yes yes
FLRT1_HUMAN [view interactions] High throughput no no
CLC4A_HUMAN [view interactions] High throughput no no
SLIRP_HUMAN [view interactions] High throughput no yes
CLC4D_HUMAN [view interactions] High throughput no no
MYO6_HUMAN [view entry] [view interactions] Computational yes no
HGF_HUMAN [view interactions] Computational no yes
MMP3_HUMAN [view interactions] Computational no no
PAR6A_HUMAN [view interactions] Computational no yes
IQGA3_HUMAN [view interactions] Computational no no
ENAH_HUMAN [view entry] [view interactions] Computational yes yes
KINH_HUMAN [view entry] [view interactions] Computational yes no
SRC_HUMAN [view entry] [view interactions] Computational yes no
NTF2_HUMAN [view interactions] Computational no yes
NECT1_HUMAN [view interactions] Computational no yes
GFRA1_HUMAN [view interactions] Computational no no
IGF2_HUMAN [view interactions] Computational no no
KPCI_HUMAN [view entry] [view interactions] Computational yes yes
MERL_HUMAN [view interactions] Computational no yes
PAK1_HUMAN [view entry] [view interactions] Computational yes yes
PK3CA_HUMAN [view entry] [view interactions] Computational yes yes
VASP_HUMAN [view interactions] Computational no yes
CTND2_HUMAN [view entry] [view interactions] Computational yes no
CAD15_HUMAN [view interactions] Computational no no
GRIA2_HUMAN [view entry] [view interactions] Computational yes yes
RAP1A_HUMAN [view entry] [view interactions] Computational yes no
EPHA2_HUMAN [view interactions] Computational no no
ACTN4_HUMAN [view entry] [view interactions] Computational yes yes
PAR3_HUMAN [view interactions] Computational no no
EXOC3_HUMAN [view entry] [view interactions] Computational yes no
ITB7_HUMAN [view interactions] Computational no no
CABL1_HUMAN [view interactions] Computational no no
NECT2_HUMAN [view interactions] Computational no no
PI51A_HUMAN [view interactions] Computational no yes
PAK2_HUMAN [view entry] [view interactions] Computational yes no
PAK3_HUMAN [view entry] [view interactions] Computational yes no
SLIT1_HUMAN [view interactions] Computational no no
PI51C_HUMAN [view entry] [view interactions] Computational yes yes
DYN2_HUMAN [view entry] [view interactions] Computational yes yes
PTPRJ_HUMAN [view interactions] Computational no yes
EFNA1_HUMAN [view interactions] Computational no no
MMP7_HUMAN [view interactions] Computational no no
BDNF_HUMAN [view interactions] Computational no yes
IGF1_HUMAN [view entry] [view interactions] Computational yes no
IQGA2_HUMAN [view interactions] Computational no yes
KIFC3_HUMAN [view interactions] Computational no no
MGAT3_HUMAN [view interactions] Computational no yes
MEP1B_HUMAN [view interactions] Computational no no
CXA1_HUMAN [view entry] [view interactions] Computational yes yes
NTRK2_HUMAN [view entry] [view interactions] Computational yes yes
VGFR2_HUMAN [view interactions] Computational no no
AJUBA_HUMAN [view interactions] Computational no yes
PTN11_HUMAN [view entry] [view interactions] Computational yes yes
MP2K6_HUMAN [view interactions] Computational no yes
PTN1_HUMAN [view interactions] Computational no yes
ACTG_HUMAN [view entry] [view interactions] Computational yes yes
EXOC4_HUMAN [view entry] [view interactions] Computational yes yes
RET_HUMAN [view interactions] Computational no yes
GDNF_HUMAN [view interactions] Computational no yes
ADA10_HUMAN [view entry] [view interactions] Computational yes yes
ITAE_HUMAN [view interactions] Computational no no
APCL_HUMAN [view entry] [view interactions] Computational yes no
ACTS_HUMAN [view interactions] Computational no no
LRP5_HUMAN [view interactions] Computational no yes
IQGA1_HUMAN [view entry] [view interactions] Computational yes no
CAH2_HUMAN [view entry] [view interactions] Computational yes no
ABL1_HUMAN [view entry] [view interactions] Computational yes yes
RAB5A_HUMAN [view entry] [view interactions] Computational yes yes
GNA13_HUMAN [view entry] [view interactions] Computational yes yes
GNA12_HUMAN [view interactions] Computational no no
STX4_HUMAN [view entry] [view interactions] Computational yes no
ROBO1_HUMAN [view interactions] Computational no yes
CAD17_HUMAN [view interactions] Computational no no
FYN_HUMAN [view entry] [view interactions] Computational yes no
FER_HUMAN [view interactions] Computational no yes
P85A_HUMAN [view interactions] Computational no yes
EGF_HUMAN [view interactions] Computational no no
RAP1B_HUMAN [view entry] [view interactions] Computational yes no
KPCZ_HUMAN [view entry] [view interactions] Computational yes yes