CTNA1_HUMAN
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. Involved in the regulation of WWTR1/TAZ, YAP1 and TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation . May play a crucial role in cell differentiation. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in CTNA1_HUMAN |
---|---|---|---|---|
GO:0043168 | anion binding | 31.2057 | 4 | no |
GO:0000166 | nucleotide binding | 30.4965 | 4 | no |
GO:0017076 | purine nucleotide binding | 29.7872 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 26.9504 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 26.9504 | 4 | no |
GO:0019900 | kinase binding | 23.4043 | 4 | no |
GO:0019901 | protein kinase binding | 22.6950 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 20.5674 | 6 | no |
GO:0045296 | cadherin binding | 19.8582 | 4 | yes |
GO:0003779 | actin binding | 17.7305 | 4 | yes |
GO:0003723 | RNA binding | 16.3121 | 4 | yes |
GO:0017166 | vinculin binding | 3.5461 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in CTNA1_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 63.1206 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 51.0638 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 49.6454 | 4 | no |
GO:0010646 | regulation of cell communication | 49.6454 | 4 | yes |
GO:0009966 | regulation of signal transduction | 46.8085 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 44.6809 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 44.6809 | 4 | no |
GO:0022607 | cellular component assembly | 43.9716 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 41.1348 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 38.2979 | 4 | no |
GO:0008104 | protein localization | 37.5887 | 4 | yes |
GO:0006996 | organelle organization | 36.1702 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 36.1702 | 5 | no |
GO:0009889 | regulation of biosynthetic process | 36.1702 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 35.4610 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 35.4610 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 34.0426 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 32.6241 | 4 | yes |
GO:0010468 | regulation of gene expression | 32.6241 | 6 | no |
GO:0051246 | regulation of protein metabolic process | 30.4965 | 5 | no |
GO:0023056 | positive regulation of signaling | 30.4965 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 29.7872 | 5 | yes |
GO:0051130 | positive regulation of cellular component organization | 29.0780 | 5 | no |
GO:0030030 | cell projection organization | 29.0780 | 4 | yes |
GO:0051049 | regulation of transport | 28.3688 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 28.3688 | 5 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 27.6596 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 26.9504 | 4 | yes |
GO:0060341 | regulation of cellular localization | 26.9504 | 4 | yes |
GO:0034330 | cell junction organization | 26.9504 | 4 | yes |
GO:0044087 | regulation of cellular component biogenesis | 26.2411 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 25.5319 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 25.5319 | 5 | no |
GO:0032880 | regulation of protein localization | 25.5319 | 5 | yes |
GO:0042127 | regulation of cell population proliferation | 25.5319 | 4 | yes |
GO:2000145 | regulation of cell motility | 24.8227 | 4 | yes |
GO:0031344 | regulation of cell projection organization | 24.8227 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 24.8227 | 6 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.8227 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 24.8227 | 5 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 24.8227 | 6 | no |
GO:0045595 | regulation of cell differentiation | 24.8227 | 4 | yes |
GO:0019220 | regulation of phosphate metabolic process | 24.1135 | 6 | no |
GO:0031399 | regulation of protein modification process | 24.1135 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 24.1135 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 24.1135 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 24.1135 | 6 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.1135 | 5 | no |
GO:0043067 | regulation of programmed cell death | 24.1135 | 4 | yes |
GO:2000026 | regulation of multicellular organismal development | 23.4043 | 4 | yes |
GO:0051094 | positive regulation of developmental process | 23.4043 | 4 | no |
GO:0030334 | regulation of cell migration | 23.4043 | 5 | no |
GO:0033043 | regulation of organelle organization | 23.4043 | 5 | no |
GO:0009968 | negative regulation of signal transduction | 23.4043 | 5 | yes |
GO:0010648 | negative regulation of cell communication | 23.4043 | 5 | yes |
GO:0023057 | negative regulation of signaling | 23.4043 | 4 | yes |
GO:0042981 | regulation of apoptotic process | 23.4043 | 5 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 22.6950 | 5 | yes |
GO:0007010 | cytoskeleton organization | 22.6950 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 22.6950 | 4 | no |
GO:0042325 | regulation of phosphorylation | 21.9858 | 7 | no |
GO:0030155 | regulation of cell adhesion | 21.9858 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 21.9858 | 5 | no |
GO:0006355 | regulation of DNA-templated transcription | 21.2766 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 21.2766 | 6 | no |
GO:0071310 | cellular response to organic substance | 20.5674 | 4 | yes |
GO:0141124 | intracellular signaling cassette | 20.5674 | 4 | no |
GO:0051241 | negative regulation of multicellular organismal process | 19.8582 | 4 | yes |
GO:0060284 | regulation of cell development | 19.8582 | 5 | yes |
GO:0051960 | regulation of nervous system development | 18.4397 | 5 | yes |
GO:0010243 | response to organonitrogen compound | 17.7305 | 4 | yes |
GO:0034329 | cell junction assembly | 17.7305 | 5 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 17.0213 | 4 | yes |
GO:0050767 | regulation of neurogenesis | 15.6028 | 6 | yes |
GO:0045216 | cell-cell junction organization | 15.6028 | 5 | yes |
GO:0031175 | neuron projection development | 14.8936 | 6 | yes |
GO:0051093 | negative regulation of developmental process | 14.1844 | 4 | yes |
GO:1901699 | cellular response to nitrogen compound | 13.4752 | 4 | yes |
GO:0043066 | negative regulation of apoptotic process | 13.4752 | 6 | yes |
GO:0043069 | negative regulation of programmed cell death | 13.4752 | 5 | yes |
GO:0071417 | cellular response to organonitrogen compound | 12.7660 | 4 | yes |
GO:0007043 | cell-cell junction assembly | 11.3475 | 6 | yes |
GO:0014070 | response to organic cyclic compound | 11.3475 | 4 | yes |
GO:0045596 | negative regulation of cell differentiation | 11.3475 | 5 | yes |
GO:0008285 | negative regulation of cell population proliferation | 10.6383 | 5 | yes |
GO:0040013 | negative regulation of locomotion | 10.6383 | 4 | yes |
GO:0043068 | positive regulation of programmed cell death | 10.6383 | 5 | yes |
GO:2000146 | negative regulation of cell motility | 9.9291 | 5 | yes |
GO:2001233 | regulation of apoptotic signaling pathway | 9.9291 | 5 | yes |
GO:0043065 | positive regulation of apoptotic process | 9.2199 | 6 | yes |
GO:0071407 | cellular response to organic cyclic compound | 8.5106 | 5 | yes |
GO:0010721 | negative regulation of cell development | 8.5106 | 6 | yes |
GO:2001234 | negative regulation of apoptotic signaling pathway | 7.8014 | 6 | yes |
GO:0050768 | negative regulation of neurogenesis | 7.0922 | 6 | yes |
GO:0051961 | negative regulation of nervous system development | 7.0922 | 5 | yes |
GO:2000177 | regulation of neural precursor cell proliferation | 7.0922 | 5 | yes |
GO:1900180 | regulation of protein localization to nucleus | 6.3830 | 6 | yes |
GO:0097305 | response to alcohol | 5.6738 | 4 | yes |
GO:1903828 | negative regulation of protein localization | 5.6738 | 5 | yes |
GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 4.9645 | 6 | yes |
GO:0097306 | cellular response to alcohol | 4.2553 | 5 | yes |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 4.2553 | 7 | yes |
GO:0071680 | response to indole-3-methanol | 3.5461 | 5 | yes |
GO:0071681 | cellular response to indole-3-methanol | 3.5461 | 5 | yes |
GO:0090136 | epithelial cell-cell adhesion | 2.8369 | 4 | yes |
GO:0097191 | extrinsic apoptotic signaling pathway | 2.8369 | 4 | yes |
GO:1902692 | regulation of neuroblast proliferation | 2.8369 | 6 | yes |
GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 2.8369 | 7 | yes |
GO:0007229 | integrin-mediated signaling pathway | 2.8369 | 4 | yes |
GO:0008589 | regulation of smoothened signaling pathway | 2.8369 | 5 | yes |
GO:0042476 | odontogenesis | 2.8369 | 4 | yes |
GO:0043297 | apical junction assembly | 2.8369 | 7 | yes |
GO:0048678 | response to axon injury | 2.1277 | 4 | yes |
GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 2.1277 | 4 | yes |
GO:1900181 | negative regulation of protein localization to nucleus | 2.1277 | 6 | yes |
GO:1901099 | negative regulation of signal transduction in absence of ligand | 2.1277 | 6 | yes |
GO:2000178 | negative regulation of neural precursor cell proliferation | 2.1277 | 6 | yes |
GO:2001235 | positive regulation of apoptotic signaling pathway | 2.1277 | 6 | yes |
GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | 2.1277 | 7 | yes |
GO:0007224 | smoothened signaling pathway | 2.1277 | 4 | yes |
GO:0007405 | neuroblast proliferation | 2.1277 | 4 | yes |
GO:0008406 | gonad development | 2.1277 | 4 | yes |
GO:0008584 | male gonad development | 2.1277 | 5 | yes |
GO:0042475 | odontogenesis of dentin-containing tooth | 2.1277 | 5 | yes |
GO:0045880 | positive regulation of smoothened signaling pathway | 2.1277 | 6 | yes |
GO:0061564 | axon development | 1.4184 | 7 | yes |
GO:2001044 | regulation of integrin-mediated signaling pathway | 1.4184 | 5 | yes |
GO:2001045 | negative regulation of integrin-mediated signaling pathway | 1.4184 | 6 | yes |
GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway | 1.4184 | 7 | yes |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1.4184 | 8 | yes |
GO:0007406 | negative regulation of neuroblast proliferation | 1.4184 | 7 | yes |
GO:0016264 | gap junction assembly | 1.4184 | 7 | yes |
GO:0031102 | neuron projection regeneration | 1.4184 | 4 | yes |
GO:0031103 | axon regeneration | 1.4184 | 5 | yes |
GO:0043627 | response to estrogen | 1.4184 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
SCRIB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CEP55_HUMAN | [view interactions] | Low throughput | no | yes |
PDLI7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ZO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SPTB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AFAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CE350_HUMAN | [view interactions] | Low throughput | no | yes |
ARMC8_HUMAN | [view interactions] | Low throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PLAK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
VINC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
RGAP1_HUMAN | [view interactions] | Low throughput | no | no |
ECT2_HUMAN | [view interactions] | Low throughput | no | no |
IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
BCL9_HUMAN | [view interactions] | Low throughput | no | yes |
BCL9L_HUMAN | [view interactions] | Low throughput | no | no |
CADH5_HUMAN | [view interactions] | Low throughput | no | yes |
PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
LIMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TF65_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
OBI1_HUMAN | [view interactions] | Low throughput | no | yes |
ACTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRAT2_HUMAN | [view interactions] | Low throughput | no | yes |
B2MG_HUMAN | [view interactions] | Low throughput | no | yes |
IQEC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CTND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CADH3_HUMAN | [view interactions] | Low throughput | no | no |
CADH2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CAH9_HUMAN | [view interactions] | Low throughput | no | no |
PTN14_HUMAN | [view interactions] | Low throughput | no | yes |
VEZA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MYO7A_HUMAN | [view interactions] | Low throughput | no | yes |
PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FMN1_HUMAN | [view interactions] | Low throughput | no | no |
NUMB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
E2F4_HUMAN | [view interactions] | High throughput | no | no |
OVOL2_HUMAN | [view interactions] | High throughput | no | no |
ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
CAVN3_HUMAN | [view interactions] | High throughput | no | no |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GCSP_HUMAN | [view interactions] | High throughput | no | yes |
MOB3C_HUMAN | [view interactions] | High throughput | no | no |
MIDN_HUMAN | [view interactions] | High throughput | no | no |
SPOP_HUMAN | [view interactions] | High throughput | no | no |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
EGR2_HUMAN | [view interactions] | High throughput | no | no |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GARS_HUMAN | [view interactions] | High throughput | no | yes |
OSBP1_HUMAN | [view interactions] | High throughput | no | yes |
SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP11_HUMAN | [view interactions] | High throughput | no | yes |
XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CUL2_HUMAN | [view interactions] | High throughput | no | yes |
IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANM3_HUMAN | [view interactions] | High throughput | no | yes |
XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CATL1_HUMAN | [view interactions] | High throughput | no | yes |
SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
K1C18_HUMAN | [view interactions] | High throughput | no | no |
SYEP_HUMAN | [view interactions] | High throughput | no | yes |
PLST_HUMAN | [view interactions] | High throughput | no | yes |
SYWC_HUMAN | [view interactions] | High throughput | no | yes |
SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
METK2_HUMAN | [view interactions] | High throughput | no | no |
FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SYCC_HUMAN | [view interactions] | High throughput | no | yes |
SERPH_HUMAN | [view interactions] | High throughput | no | no |
TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IF4A1_HUMAN | [view interactions] | High throughput | no | no |
EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DPOA2_HUMAN | [view interactions] | High throughput | no | yes |
SYK_HUMAN | [view interactions] | High throughput | no | yes |
ELOB_HUMAN | [view interactions] | High throughput | no | no |
TSN_HUMAN | [view interactions] | High throughput | no | yes |
CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CARM1_HUMAN | [view interactions] | High throughput | no | yes |
ANKY2_HUMAN | [view interactions] | High throughput | no | no |
SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IKKB_HUMAN | [view interactions] | High throughput | no | yes |
IPO9_HUMAN | [view interactions] | High throughput | no | no |
CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LS14B_HUMAN | [view interactions] | High throughput | no | yes |
ATX10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTR1A_HUMAN | [view interactions] | High throughput | no | no |
CBPA4_HUMAN | [view interactions] | High throughput | no | no |
MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
PRP19_HUMAN | [view interactions] | High throughput | no | yes |
PSD13_HUMAN | [view interactions] | High throughput | no | yes |
TRI33_HUMAN | [view interactions] | High throughput | no | yes |
GLUT4_HUMAN | [view interactions] | High throughput | no | no |
AGR2_HUMAN | [view interactions] | High throughput | no | no |
ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DPPA3_HUMAN | [view interactions] | High throughput | no | no |
DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARAF_HUMAN | [view interactions] | High throughput | no | yes |
ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ILK_HUMAN | [view interactions] | High throughput | no | no |
CK052_HUMAN | [view interactions] | High throughput | no | no |
BMR1A_HUMAN | [view interactions] | High throughput | no | no |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
ANR26_HUMAN | [view interactions] | High throughput | no | yes |
RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
CC85C_HUMAN | [view interactions] | High throughput | no | yes |
FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
GRDN_HUMAN | [view interactions] | High throughput | no | no |
MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DAPLE_HUMAN | [view interactions] | High throughput | no | yes |
NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
CENPF_HUMAN | [view interactions] | High throughput | no | no |
CETN2_HUMAN | [view interactions] | High throughput | no | yes |
CING_HUMAN | [view interactions] | High throughput | no | no |
GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
CLMN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DSG2_HUMAN | [view interactions] | High throughput | no | no |
TGFR1_HUMAN | [view interactions] | High throughput | no | no |
ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
F110B_HUMAN | [view interactions] | High throughput | no | yes |
JCAD_HUMAN | [view interactions] | High throughput | no | yes |
LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DUS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LZTS2_HUMAN | [view interactions] | High throughput | no | no |
CSK_HUMAN | [view interactions] | High throughput | no | yes |
MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAGI1_HUMAN | [view interactions] | High throughput | no | no |
GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUF4_HUMAN | [view interactions] | High throughput | no | yes |
RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NHS_HUMAN | [view interactions] | High throughput | no | yes |
RHG23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKP2_HUMAN | [view interactions] | High throughput | no | yes |
ECT2L_HUMAN | [view interactions] | High throughput | no | no |
PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
PLCH1_HUMAN | [view interactions] | High throughput | no | no |
DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
E2F3_HUMAN | [view interactions] | High throughput | no | no |
GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RINT1_HUMAN | [view interactions] | High throughput | no | yes |
SI1L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SIR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TF7L2_HUMAN | [view interactions] | High throughput | no | yes |
SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
DDR2_HUMAN | [view interactions] | High throughput | no | no |
AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MET_HUMAN | [view interactions] | High throughput | no | yes |
ANR28_HUMAN | [view interactions] | High throughput | no | no |
NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
CP131_HUMAN | [view interactions] | High throughput | no | no |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DVL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNW1_HUMAN | [view interactions] | High throughput | no | yes |
ECD_HUMAN | [view interactions] | High throughput | no | yes |
CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
K1671_HUMAN | [view interactions] | High throughput | no | yes |
KDIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTBP3_HUMAN | [view interactions] | High throughput | no | no |
LIMD1_HUMAN | [view interactions] | High throughput | no | yes |
MCM7_HUMAN | [view interactions] | High throughput | no | no |
LMO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
JUN_HUMAN | [view interactions] | High throughput | no | yes |
LRC49_HUMAN | [view interactions] | High throughput | no | no |
PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M4K4_HUMAN | [view interactions] | High throughput | no | yes |
MARK3_HUMAN | [view interactions] | High throughput | no | yes |
ANGI_HUMAN | [view interactions] | High throughput | no | no |
NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEBL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PEX5R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
RYR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHAR4_HUMAN | [view interactions] | High throughput | no | yes |
LITD1_HUMAN | [view interactions] | High throughput | no | no |
RASF8_HUMAN | [view interactions] | High throughput | no | yes |
INSR_HUMAN | [view interactions] | High throughput | no | yes |
ENTR1_HUMAN | [view interactions] | High throughput | no | no |
CD81_HUMAN | [view interactions] | High throughput | no | no |
SI1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UTRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
E41LA_HUMAN | [view interactions] | High throughput | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ALDOB_HUMAN | [view interactions] | High throughput | no | no |
FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAAT_HUMAN | [view interactions] | High throughput | no | no |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CATL2_HUMAN | [view interactions] | High throughput | no | yes |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
F16P1_HUMAN | [view interactions] | High throughput | no | no |
MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
F16P2_HUMAN | [view interactions] | High throughput | no | no |
NU155_HUMAN | [view interactions] | High throughput | no | yes |
FRAT2_HUMAN | [view interactions] | High throughput | no | no |
OCLN_HUMAN | [view interactions] | High throughput | no | no |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DHB3_HUMAN | [view interactions] | High throughput | no | no |
STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CC180_HUMAN | [view interactions] | High throughput | no | no |
ZYX_HUMAN | [view interactions] | High throughput | no | no |
MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SIAS_HUMAN | [view interactions] | High throughput | no | yes |
STING_HUMAN | [view interactions] | High throughput | no | yes |
SFRP2_HUMAN | [view interactions] | High throughput | no | no |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SFRP4_HUMAN | [view interactions] | High throughput | no | no |
ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STX17_HUMAN | [view interactions] | High throughput | no | yes |
CD44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TDRD7_HUMAN | [view interactions] | High throughput | no | yes |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN189_HUMAN | [view interactions] | High throughput | no | yes |
FERM2_HUMAN | [view interactions] | High throughput | no | yes |
ZN510_HUMAN | [view interactions] | High throughput | no | yes |
LPP_HUMAN | [view interactions] | High throughput | no | yes |
NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZGPAT_HUMAN | [view interactions] | High throughput | no | no |
PTN13_HUMAN | [view interactions] | High throughput | no | yes |
PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SEPT2_HUMAN | [view interactions] | High throughput | no | no |
CSN5_HUMAN | [view interactions] | High throughput | no | yes |
SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NEK4_HUMAN | [view interactions] | High throughput | no | yes |
STEA3_HUMAN | [view interactions] | High throughput | no | yes |
NHRF2_HUMAN | [view interactions] | High throughput | no | no |
TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
YKT6_HUMAN | [view interactions] | High throughput | no | yes |
HSP13_HUMAN | [view interactions] | High throughput | no | yes |
TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RFA2_HUMAN | [view interactions] | High throughput | no | yes |
CTDSL_HUMAN | [view interactions] | High throughput | no | no |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |
EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MUC18_HUMAN | [view interactions] | High throughput | no | yes |
EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCNK3_HUMAN | [view interactions] | High throughput | no | no |
NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SASH1_HUMAN | [view interactions] | High throughput | no | yes |
4ET_HUMAN | [view interactions] | High throughput | no | yes |
RBM26_HUMAN | [view interactions] | High throughput | no | yes |
DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
PCP2_HUMAN | [view interactions] | High throughput | no | no |
RYK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SIR7_HUMAN | [view interactions] | High throughput | no | yes |
TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNA3_HUMAN | [view interactions] | High throughput | no | no |
OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
EED_HUMAN | [view interactions] | High throughput | no | yes |
FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
UNK_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
HERC2_HUMAN | [view interactions] | High throughput | no | yes |
MCM2_HUMAN | [view interactions] | High throughput | no | no |
CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
CF298_HUMAN | [view interactions] | High throughput | no | yes |
RAD18_HUMAN | [view interactions] | High throughput | no | yes |
CADH8_HUMAN | [view interactions] | High throughput | no | no |
CNBP1_HUMAN | [view interactions] | High throughput | no | no |
DMD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SAPC1_HUMAN | [view interactions] | High throughput | no | no |
SLAF7_HUMAN | [view interactions] | High throughput | no | no |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
UBE2A_HUMAN | [view interactions] | High throughput | no | no |
BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
TES_HUMAN | [view interactions] | High throughput | no | yes |
EGLN3_HUMAN | [view interactions] | High throughput | no | no |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
SUZ12_HUMAN | [view interactions] | High throughput | no | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
TISD_HUMAN | [view interactions] | High throughput | no | no |
CDK9_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
DUS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LMBRL_HUMAN | [view interactions] | High throughput | no | no |
CUL7_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WDR76_HUMAN | [view interactions] | High throughput | no | no |
INSI1_HUMAN | [view interactions] | High throughput | no | no |
ANDR_HUMAN | [view interactions] | High throughput | no | no |
WDR5_HUMAN | [view interactions] | High throughput | no | no |
CAD12_HUMAN | [view interactions] | High throughput | no | no |
TX1B3_HUMAN | [view interactions] | High throughput | no | no |
CTNA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLRT1_HUMAN | [view interactions] | High throughput | no | no |
CLC4A_HUMAN | [view interactions] | High throughput | no | no |
SLIRP_HUMAN | [view interactions] | High throughput | no | yes |
CLC4D_HUMAN | [view interactions] | High throughput | no | no |
RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
RHOQ_HUMAN | [view interactions] | High throughput | no | no |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOF_HUMAN | [view interactions] | High throughput | no | no |
RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
RHOD_HUMAN | [view interactions] | High throughput | no | no |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RANG_HUMAN | [view interactions] | High throughput | no | no |
TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |