CTNA1_HUMAN
Evidence for PS localization
Functions
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. Involved in the regulation of WWTR1/TAZ, YAP1 and TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation . May play a crucial role in cell differentiation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CTNA1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 31.2057 | 4 | no |
| GO:0000166 | nucleotide binding | 30.4965 | 4 | no |
| GO:0017076 | purine nucleotide binding | 29.7872 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 26.9504 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.9504 | 4 | no |
| GO:0019900 | kinase binding | 23.4043 | 4 | no |
| GO:0019901 | protein kinase binding | 22.6950 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 20.5674 | 6 | no |
| GO:0045296 | cadherin binding | 19.8582 | 4 | yes |
| GO:0003779 | actin binding | 17.7305 | 4 | yes |
| GO:0003723 | RNA binding | 16.3121 | 4 | yes |
| GO:0017166 | vinculin binding | 3.5461 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CTNA1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 63.1206 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 51.0638 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 49.6454 | 4 | no |
| GO:0010646 | regulation of cell communication | 49.6454 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 46.8085 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 44.6809 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 44.6809 | 4 | no |
| GO:0022607 | cellular component assembly | 43.9716 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 41.1348 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.2979 | 4 | no |
| GO:0008104 | protein localization | 37.5887 | 4 | yes |
| GO:0006996 | organelle organization | 36.1702 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.1702 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 36.1702 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.4610 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 35.4610 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 34.0426 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 32.6241 | 4 | yes |
| GO:0010468 | regulation of gene expression | 32.6241 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 30.4965 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.4965 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 29.7872 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 29.0780 | 5 | no |
| GO:0030030 | cell projection organization | 29.0780 | 4 | yes |
| GO:0051049 | regulation of transport | 28.3688 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.3688 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 27.6596 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.9504 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 26.9504 | 4 | yes |
| GO:0034330 | cell junction organization | 26.9504 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 26.2411 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 25.5319 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 25.5319 | 5 | no |
| GO:0032880 | regulation of protein localization | 25.5319 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 25.5319 | 4 | yes |
| GO:2000145 | regulation of cell motility | 24.8227 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 24.8227 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.8227 | 6 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.8227 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 24.8227 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 24.8227 | 6 | no |
| GO:0045595 | regulation of cell differentiation | 24.8227 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 24.1135 | 6 | no |
| GO:0031399 | regulation of protein modification process | 24.1135 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.1135 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.1135 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 24.1135 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.1135 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 24.1135 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 23.4043 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 23.4043 | 4 | no |
| GO:0030334 | regulation of cell migration | 23.4043 | 5 | no |
| GO:0033043 | regulation of organelle organization | 23.4043 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 23.4043 | 5 | yes |
| GO:0010648 | negative regulation of cell communication | 23.4043 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 23.4043 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 23.4043 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 22.6950 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 22.6950 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.6950 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 21.9858 | 7 | no |
| GO:0030155 | regulation of cell adhesion | 21.9858 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 21.9858 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 21.2766 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.2766 | 6 | no |
| GO:0071310 | cellular response to organic substance | 20.5674 | 4 | yes |
| GO:0141124 | intracellular signaling cassette | 20.5674 | 4 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 19.8582 | 4 | yes |
| GO:0060284 | regulation of cell development | 19.8582 | 5 | yes |
| GO:0051960 | regulation of nervous system development | 18.4397 | 5 | yes |
| GO:0010243 | response to organonitrogen compound | 17.7305 | 4 | yes |
| GO:0034329 | cell junction assembly | 17.7305 | 5 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 17.0213 | 4 | yes |
| GO:0050767 | regulation of neurogenesis | 15.6028 | 6 | yes |
| GO:0045216 | cell-cell junction organization | 15.6028 | 5 | yes |
| GO:0031175 | neuron projection development | 14.8936 | 6 | yes |
| GO:0051093 | negative regulation of developmental process | 14.1844 | 4 | yes |
| GO:1901699 | cellular response to nitrogen compound | 13.4752 | 4 | yes |
| GO:0043066 | negative regulation of apoptotic process | 13.4752 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 13.4752 | 5 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 12.7660 | 4 | yes |
| GO:0007043 | cell-cell junction assembly | 11.3475 | 6 | yes |
| GO:0014070 | response to organic cyclic compound | 11.3475 | 4 | yes |
| GO:0045596 | negative regulation of cell differentiation | 11.3475 | 5 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 10.6383 | 5 | yes |
| GO:0040013 | negative regulation of locomotion | 10.6383 | 4 | yes |
| GO:0043068 | positive regulation of programmed cell death | 10.6383 | 5 | yes |
| GO:2000146 | negative regulation of cell motility | 9.9291 | 5 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 9.9291 | 5 | yes |
| GO:0043065 | positive regulation of apoptotic process | 9.2199 | 6 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 8.5106 | 5 | yes |
| GO:0010721 | negative regulation of cell development | 8.5106 | 6 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 7.8014 | 6 | yes |
| GO:0050768 | negative regulation of neurogenesis | 7.0922 | 6 | yes |
| GO:0051961 | negative regulation of nervous system development | 7.0922 | 5 | yes |
| GO:2000177 | regulation of neural precursor cell proliferation | 7.0922 | 5 | yes |
| GO:1900180 | regulation of protein localization to nucleus | 6.3830 | 6 | yes |
| GO:0097305 | response to alcohol | 5.6738 | 4 | yes |
| GO:1903828 | negative regulation of protein localization | 5.6738 | 5 | yes |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 4.9645 | 6 | yes |
| GO:0097306 | cellular response to alcohol | 4.2553 | 5 | yes |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 4.2553 | 7 | yes |
| GO:0071680 | response to indole-3-methanol | 3.5461 | 5 | yes |
| GO:0071681 | cellular response to indole-3-methanol | 3.5461 | 5 | yes |
| GO:0090136 | epithelial cell-cell adhesion | 2.8369 | 4 | yes |
| GO:0097191 | extrinsic apoptotic signaling pathway | 2.8369 | 4 | yes |
| GO:1902692 | regulation of neuroblast proliferation | 2.8369 | 6 | yes |
| GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 2.8369 | 7 | yes |
| GO:0007229 | integrin-mediated signaling pathway | 2.8369 | 4 | yes |
| GO:0008589 | regulation of smoothened signaling pathway | 2.8369 | 5 | yes |
| GO:0042476 | odontogenesis | 2.8369 | 4 | yes |
| GO:0043297 | apical junction assembly | 2.8369 | 7 | yes |
| GO:0048678 | response to axon injury | 2.1277 | 4 | yes |
| GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 2.1277 | 4 | yes |
| GO:1900181 | negative regulation of protein localization to nucleus | 2.1277 | 6 | yes |
| GO:1901099 | negative regulation of signal transduction in absence of ligand | 2.1277 | 6 | yes |
| GO:2000178 | negative regulation of neural precursor cell proliferation | 2.1277 | 6 | yes |
| GO:2001235 | positive regulation of apoptotic signaling pathway | 2.1277 | 6 | yes |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | 2.1277 | 7 | yes |
| GO:0007224 | smoothened signaling pathway | 2.1277 | 4 | yes |
| GO:0007405 | neuroblast proliferation | 2.1277 | 4 | yes |
| GO:0008406 | gonad development | 2.1277 | 4 | yes |
| GO:0008584 | male gonad development | 2.1277 | 5 | yes |
| GO:0042475 | odontogenesis of dentin-containing tooth | 2.1277 | 5 | yes |
| GO:0045880 | positive regulation of smoothened signaling pathway | 2.1277 | 6 | yes |
| GO:0061564 | axon development | 1.4184 | 7 | yes |
| GO:2001044 | regulation of integrin-mediated signaling pathway | 1.4184 | 5 | yes |
| GO:2001045 | negative regulation of integrin-mediated signaling pathway | 1.4184 | 6 | yes |
| GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway | 1.4184 | 7 | yes |
| GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1.4184 | 8 | yes |
| GO:0007406 | negative regulation of neuroblast proliferation | 1.4184 | 7 | yes |
| GO:0016264 | gap junction assembly | 1.4184 | 7 | yes |
| GO:0031102 | neuron projection regeneration | 1.4184 | 4 | yes |
| GO:0031103 | axon regeneration | 1.4184 | 5 | yes |
| GO:0043627 | response to estrogen | 1.4184 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SCRIB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CEP55_HUMAN | [view interactions] | Low throughput | no | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ZO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SPTB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AFAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CE350_HUMAN | [view interactions] | Low throughput | no | yes |
| ARMC8_HUMAN | [view interactions] | Low throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLAK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VINC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RGAP1_HUMAN | [view interactions] | Low throughput | no | no |
| ECT2_HUMAN | [view interactions] | Low throughput | no | no |
| IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
| BCL9_HUMAN | [view interactions] | Low throughput | no | yes |
| BCL9L_HUMAN | [view interactions] | Low throughput | no | no |
| CADH5_HUMAN | [view interactions] | Low throughput | no | yes |
| PARD3_HUMAN | [view interactions] | Low throughput | no | yes |
| YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TF65_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OBI1_HUMAN | [view interactions] | Low throughput | no | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRAT2_HUMAN | [view interactions] | Low throughput | no | yes |
| B2MG_HUMAN | [view interactions] | Low throughput | no | yes |
| IQEC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CADH3_HUMAN | [view interactions] | Low throughput | no | no |
| CADH2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CAH9_HUMAN | [view interactions] | Low throughput | no | no |
| PTN14_HUMAN | [view interactions] | Low throughput | no | yes |
| VEZA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYO7A_HUMAN | [view interactions] | Low throughput | no | yes |
| PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FMN1_HUMAN | [view interactions] | Low throughput | no | no |
| NUMB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| OVOL2_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCSP_HUMAN | [view interactions] | High throughput | no | yes |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| EGR2_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GARS_HUMAN | [view interactions] | High throughput | no | yes |
| OSBP1_HUMAN | [view interactions] | High throughput | no | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM3_HUMAN | [view interactions] | High throughput | no | yes |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| SYEP_HUMAN | [view interactions] | High throughput | no | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| METK2_HUMAN | [view interactions] | High throughput | no | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYCC_HUMAN | [view interactions] | High throughput | no | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4A1_HUMAN | [view interactions] | High throughput | no | no |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPOA2_HUMAN | [view interactions] | High throughput | no | yes |
| SYK_HUMAN | [view interactions] | High throughput | no | yes |
| ELOB_HUMAN | [view interactions] | High throughput | no | no |
| TSN_HUMAN | [view interactions] | High throughput | no | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| ANKY2_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IKKB_HUMAN | [view interactions] | High throughput | no | yes |
| IPO9_HUMAN | [view interactions] | High throughput | no | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LS14B_HUMAN | [view interactions] | High throughput | no | yes |
| ATX10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| CBPA4_HUMAN | [view interactions] | High throughput | no | no |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| BMR1A_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| ANR26_HUMAN | [view interactions] | High throughput | no | yes |
| RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
| CC85C_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| GRDN_HUMAN | [view interactions] | High throughput | no | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAPLE_HUMAN | [view interactions] | High throughput | no | yes |
| NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPF_HUMAN | [view interactions] | High throughput | no | no |
| CETN2_HUMAN | [view interactions] | High throughput | no | yes |
| CING_HUMAN | [view interactions] | High throughput | no | no |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| CLMN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSG2_HUMAN | [view interactions] | High throughput | no | no |
| TGFR1_HUMAN | [view interactions] | High throughput | no | no |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F110B_HUMAN | [view interactions] | High throughput | no | yes |
| JCAD_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGI1_HUMAN | [view interactions] | High throughput | no | no |
| GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUF4_HUMAN | [view interactions] | High throughput | no | yes |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHS_HUMAN | [view interactions] | High throughput | no | yes |
| RHG23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKP2_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2L_HUMAN | [view interactions] | High throughput | no | no |
| PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| PLCH1_HUMAN | [view interactions] | High throughput | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
| E2F3_HUMAN | [view interactions] | High throughput | no | no |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RINT1_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TF7L2_HUMAN | [view interactions] | High throughput | no | yes |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| DDR2_HUMAN | [view interactions] | High throughput | no | no |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| ANR28_HUMAN | [view interactions] | High throughput | no | no |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| CP131_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| ECD_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| K1671_HUMAN | [view interactions] | High throughput | no | yes |
| KDIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| LIMD1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| LMO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| LRC49_HUMAN | [view interactions] | High throughput | no | no |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| MARK3_HUMAN | [view interactions] | High throughput | no | yes |
| ANGI_HUMAN | [view interactions] | High throughput | no | no |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEBL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PEX5R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
| RYR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHAR4_HUMAN | [view interactions] | High throughput | no | yes |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| RASF8_HUMAN | [view interactions] | High throughput | no | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| ENTR1_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| SI1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UTRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALDOB_HUMAN | [view interactions] | High throughput | no | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAAT_HUMAN | [view interactions] | High throughput | no | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CATL2_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F16P2_HUMAN | [view interactions] | High throughput | no | no |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| FRAT2_HUMAN | [view interactions] | High throughput | no | no |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHB3_HUMAN | [view interactions] | High throughput | no | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC180_HUMAN | [view interactions] | High throughput | no | no |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIAS_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| SFRP2_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SFRP4_HUMAN | [view interactions] | High throughput | no | no |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| CD44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TDRD7_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN189_HUMAN | [view interactions] | High throughput | no | yes |
| FERM2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN510_HUMAN | [view interactions] | High throughput | no | yes |
| LPP_HUMAN | [view interactions] | High throughput | no | yes |
| NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZGPAT_HUMAN | [view interactions] | High throughput | no | no |
| PTN13_HUMAN | [view interactions] | High throughput | no | yes |
| PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT2_HUMAN | [view interactions] | High throughput | no | no |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| STEA3_HUMAN | [view interactions] | High throughput | no | yes |
| NHRF2_HUMAN | [view interactions] | High throughput | no | no |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| HSP13_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| CTDSL_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SASH1_HUMAN | [view interactions] | High throughput | no | yes |
| 4ET_HUMAN | [view interactions] | High throughput | no | yes |
| RBM26_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
| PCP2_HUMAN | [view interactions] | High throughput | no | no |
| RYK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| CF298_HUMAN | [view interactions] | High throughput | no | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| CADH8_HUMAN | [view interactions] | High throughput | no | no |
| CNBP1_HUMAN | [view interactions] | High throughput | no | no |
| DMD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAPC1_HUMAN | [view interactions] | High throughput | no | no |
| SLAF7_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| TISD_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| DUS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| INSI1_HUMAN | [view interactions] | High throughput | no | no |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| CAD12_HUMAN | [view interactions] | High throughput | no | no |
| TX1B3_HUMAN | [view interactions] | High throughput | no | no |
| CTNA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLRT1_HUMAN | [view interactions] | High throughput | no | no |
| CLC4A_HUMAN | [view interactions] | High throughput | no | no |
| SLIRP_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RANG_HUMAN | [view interactions] | High throughput | no | no |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |