Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ANK3_HUMAN

May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin. [View more on UniProt]

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Download full PS network for entry.

No data found.

ELM instance Name Type Start End Partner
ELMI001681 LIG_EVH1_1 LIG 3254 3258 -

Molecular function

Term Name % Distance from the top of the tree Annotated in ANK3_HUMAN
GO:0019900 kinase binding 30.5882 4 no
GO:0019901 protein kinase binding 28.2353 5 no
GO:0017076 purine nucleotide binding 24.7059 4 no
GO:0032555 purine ribonucleotide binding 24.7059 4 no
GO:0035639 purine ribonucleoside triphosphate binding 24.7059 4 no
GO:0045296 cadherin binding 16.4706 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ANK3_HUMAN
GO:0048522 positive regulation of cellular process 64.7059 4 yes
GO:0022607 cellular component assembly 51.7647 4 yes
GO:0060255 regulation of macromolecule metabolic process 50.5882 4 yes
GO:0048523 negative regulation of cellular process 47.0588 4 yes
GO:0051128 regulation of cellular component organization 47.0588 4 no
GO:0006996 organelle organization 45.8824 4 no
GO:0010646 regulation of cell communication 44.7059 4 yes
GO:0031323 regulation of cellular metabolic process 43.5294 4 no
GO:0051171 regulation of nitrogen compound metabolic process 43.5294 4 no
GO:0080090 regulation of primary metabolic process 43.5294 4 no
GO:0008104 protein localization 42.3529 4 yes
GO:0009893 positive regulation of metabolic process 42.3529 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 42.3529 5 yes
GO:0009966 regulation of signal transduction 41.1765 4 no
GO:0030030 cell projection organization 37.6471 4 yes
GO:0051049 regulation of transport 37.6471 4 yes
GO:0010468 regulation of gene expression 35.2941 5 yes
GO:0007010 cytoskeleton organization 35.2941 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 32.9412 5 no
GO:0051246 regulation of protein metabolic process 32.9412 5 no
GO:0031325 positive regulation of cellular metabolic process 30.5882 5 no
GO:0048584 positive regulation of response to stimulus 30.5882 4 no
GO:0051094 positive regulation of developmental process 30.5882 4 no
GO:1902531 regulation of intracellular signal transduction 30.5882 5 no
GO:0010647 positive regulation of cell communication 29.4118 5 yes
GO:0034330 cell junction organization 29.4118 4 yes
GO:0023056 positive regulation of signaling 28.2353 4 no
GO:0043085 positive regulation of catalytic activity 28.2353 4 no
GO:0120036 plasma membrane bounded cell projection organization 27.0588 5 no
GO:0009892 negative regulation of metabolic process 27.0588 4 no
GO:0016192 vesicle-mediated transport 25.8824 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 25.8824 4 no
GO:0031344 regulation of cell projection organization 25.8824 5 no
GO:0044087 regulation of cellular component biogenesis 25.8824 4 no
GO:0045595 regulation of cell differentiation 25.8824 4 no
GO:0051240 positive regulation of multicellular organismal process 25.8824 4 no
GO:0071310 cellular response to organic substance 25.8824 4 no
GO:0019220 regulation of phosphate metabolic process 25.8824 6 no
GO:0031399 regulation of protein modification process 25.8824 6 no
GO:0042325 regulation of phosphorylation 25.8824 7 no
GO:0051174 regulation of phosphorus metabolic process 25.8824 5 no
GO:0009967 positive regulation of signal transduction 24.7059 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 24.7059 6 no
GO:2000026 regulation of multicellular organismal development 24.7059 4 no
GO:0043269 regulation of ion transport 23.5294 5 yes
GO:0060341 regulation of cellular localization 23.5294 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 23.5294 5 no
GO:0033043 regulation of organelle organization 23.5294 5 no
GO:0051130 positive regulation of cellular component organization 23.5294 5 no
GO:0034329 cell junction assembly 23.5294 5 no
GO:0001932 regulation of protein phosphorylation 23.5294 7 no
GO:0051247 positive regulation of protein metabolic process 23.5294 6 no
GO:0032880 regulation of protein localization 22.3529 5 yes
GO:0061024 membrane organization 22.3529 4 yes
GO:1901701 cellular response to oxygen-containing compound 22.3529 4 no
GO:0009889 regulation of biosynthetic process 22.3529 4 no
GO:0031326 regulation of cellular biosynthetic process 22.3529 5 no
GO:0031175 neuron projection development 22.3529 6 no
GO:0010605 negative regulation of macromolecule metabolic process 22.3529 5 no
GO:0010941 regulation of cell death 22.3529 4 no
GO:0045597 positive regulation of cell differentiation 21.1765 5 no
GO:2000145 regulation of cell motility 21.1765 4 no
GO:0036211 protein modification process 21.1765 4 no
GO:0043412 macromolecule modification 21.1765 4 no
GO:0042127 regulation of cell population proliferation 21.1765 4 no
GO:0032990 cell part morphogenesis 20.0000 4 yes
GO:0030155 regulation of cell adhesion 18.8235 4 yes
GO:0048812 neuron projection morphogenesis 18.8235 7 yes
GO:0048858 cell projection morphogenesis 18.8235 5 yes
GO:0071702 organic substance transport 18.8235 4 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 18.8235 6 yes
GO:0034762 regulation of transmembrane transport 17.6471 4 yes
GO:0051050 positive regulation of transport 17.6471 4 yes
GO:0071705 nitrogen compound transport 17.6471 4 yes
GO:0010628 positive regulation of gene expression 16.4706 6 yes
GO:0034765 regulation of ion transmembrane transport 16.4706 5 yes
GO:0072657 protein localization to membrane 16.4706 4 yes
GO:0050808 synapse organization 15.2941 5 yes
GO:0010959 regulation of metal ion transport 14.1176 6 yes
GO:0045785 positive regulation of cell adhesion 14.1176 5 yes
GO:1903829 positive regulation of protein localization 14.1176 5 yes
GO:1990778 protein localization to cell periphery 14.1176 5 yes
GO:0015031 protein transport 12.9412 4 yes
GO:0022898 regulation of transmembrane transporter activity 12.9412 4 yes
GO:1904062 regulation of cation transmembrane transport 12.9412 6 yes
GO:1905475 regulation of protein localization to membrane 12.9412 6 yes
GO:0010038 response to metal ion 11.7647 4 yes
GO:0032412 regulation of ion transmembrane transporter activity 11.7647 5 yes
GO:0048878 chemical homeostasis 11.7647 4 yes
GO:0072659 protein localization to plasma membrane 11.7647 5 yes
GO:0007409 axonogenesis 10.5882 8 yes
GO:0051051 negative regulation of transport 10.5882 4 yes
GO:0070201 regulation of establishment of protein localization 10.5882 6 yes
GO:0022407 regulation of cell-cell adhesion 9.4118 5 yes
GO:0043270 positive regulation of ion transport 9.4118 5 yes
GO:0050801 ion homeostasis 9.4118 5 yes
GO:0055065 metal ion homeostasis 9.4118 7 yes
GO:0055080 cation homeostasis 9.4118 6 yes
GO:0098771 inorganic ion homeostasis 9.4118 6 yes
GO:1905477 positive regulation of protein localization to membrane 9.4118 6 yes
GO:2001257 regulation of cation channel activity 9.4118 6 yes
GO:0001508 action potential 8.2353 4 yes
GO:0051223 regulation of protein transport 8.2353 5 yes
GO:0071709 membrane assembly 8.2353 5 yes
GO:0022409 positive regulation of cell-cell adhesion 7.0588 6 yes
GO:0032386 regulation of intracellular transport 7.0588 5 yes
GO:0072507 divalent inorganic cation homeostasis 7.0588 7 yes
GO:1904951 positive regulation of establishment of protein localization 7.0588 6 yes
GO:0002028 regulation of sodium ion transport 5.8824 7 yes
GO:0032388 positive regulation of intracellular transport 5.8824 5 yes
GO:0032411 positive regulation of transporter activity 5.8824 4 yes
GO:0032414 positive regulation of ion transmembrane transporter activity 5.8824 5 yes
GO:0034764 positive regulation of transmembrane transport 5.8824 5 yes
GO:0034767 positive regulation of ion transmembrane transport 5.8824 6 yes
GO:0051222 positive regulation of protein transport 5.8824 5 yes
GO:0071241 cellular response to inorganic substance 5.8824 4 yes
GO:1904064 positive regulation of cation transmembrane transport 5.8824 7 yes
GO:2001259 positive regulation of cation channel activity 5.8824 6 yes
GO:0000281 mitotic cytokinesis 4.7059 4 yes
GO:0007009 plasma membrane organization 4.7059 5 yes
GO:0033157 regulation of intracellular protein transport 4.7059 6 yes
GO:0043266 regulation of potassium ion transport 4.7059 7 yes
GO:0061640 cytoskeleton-dependent cytokinesis 4.7059 4 yes
GO:0071248 cellular response to metal ion 4.7059 5 yes
GO:1901016 regulation of potassium ion transmembrane transporter activity 4.7059 6 yes
GO:1901379 regulation of potassium ion transmembrane transport 4.7059 7 yes
GO:0007528 neuromuscular junction development 3.5294 6 yes
GO:0019228 neuronal action potential 3.5294 5 yes
GO:0032410 negative regulation of transporter activity 3.5294 4 yes
GO:0032413 negative regulation of ion transmembrane transporter activity 3.5294 5 yes
GO:0034763 negative regulation of transmembrane transport 3.5294 5 yes
GO:0034766 negative regulation of ion transmembrane transport 3.5294 6 yes
GO:0043271 negative regulation of ion transport 3.5294 5 yes
GO:0048193 Golgi vesicle transport 3.5294 5 yes
GO:0090150 establishment of protein localization to membrane 3.5294 4 yes
GO:0090316 positive regulation of intracellular protein transport 3.5294 6 yes
GO:0098876 vesicle-mediated transport to the plasma membrane 3.5294 4 yes
GO:1902305 regulation of sodium ion transmembrane transport 3.5294 7 yes
GO:1904063 negative regulation of cation transmembrane transport 3.5294 7 yes
GO:2000649 regulation of sodium ion transmembrane transporter activity 3.5294 6 yes
GO:0003254 regulation of membrane depolarization 2.3529 4 yes
GO:0006892 post-Golgi vesicle-mediated transport 2.3529 6 yes
GO:0006893 Golgi to plasma membrane transport 2.3529 5 yes
GO:0034110 regulation of homotypic cell-cell adhesion 2.3529 6 yes
GO:0043001 Golgi to plasma membrane protein transport 2.3529 5 yes
GO:0061951 establishment of protein localization to plasma membrane 2.3529 5 yes
GO:2001258 negative regulation of cation channel activity 2.3529 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in ANK3_HUMAN
DOID:331 central nervous system disease 5.8824 3 no
DOID:936 brain disease 5.8824 4 no
DOID:0050701 electroclinical syndrome 4.7059 6 no
DOID:1826 epilepsy 4.7059 5 no
DOID:0112202 developmental and epileptic encephalopathy 3.5294 7 no
DOID:114 heart disease 3.5294 3 no
DOID:0060038 specific developmental disorder 2.3529 3 no
DOID:1059 intellectual disability 2.3529 4 no
DOID:0050703 infancy electroclinical syndrome 2.3529 7 no
DOID:0060169 benign familial infantile epilepsy 2.3529 8 no
DOID:0050700 cardiomyopathy 2.3529 4 no
DOID:0060036 intrinsic cardiomyopathy 2.3529 5 no
DOID:0080000 muscular disease 2.3529 3 no
DOID:423 myopathy 2.3529 5 no
DOID:66 muscle tissue disease 2.3529 4 no
DOID:9884 muscular dystrophy 2.3529 6 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
AP3B1_HUMAN [view entry] [view interactions] Low throughput yes yes
SCN5A_HUMAN [view interactions] Low throughput no no
MARE3_HUMAN [view entry] [view interactions] Low throughput yes yes
MARE1_HUMAN [view entry] [view interactions] Low throughput yes yes
FLNC_HUMAN [view entry] [view interactions] Low throughput yes no
PLEC_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTG_HUMAN [view entry] [view interactions] Low throughput yes yes
SCN1B_HUMAN [view interactions] Low throughput no no
KCNC1_HUMAN [view entry] [view interactions] Low throughput yes yes
SPTN4_HUMAN [view entry] [view interactions] Low throughput yes no
TIAM1_HUMAN [view entry] [view interactions] Low throughput yes yes
HOOK1_HUMAN [view interactions] Low throughput no no
USP9X_HUMAN [view entry] [view interactions] Low throughput yes yes
GBRAP_HUMAN [view interactions] Low throughput no no
MLP3A_HUMAN [view entry] [view interactions] Low throughput yes yes
MLP3C_HUMAN [view interactions] Low throughput no no
GBRL1_HUMAN [view interactions] Low throughput no yes
MLP3B_HUMAN [view interactions] Low throughput no yes
L1CAM_HUMAN [view entry] [view interactions] Low throughput yes yes
SPTB2_HUMAN [view entry] [view interactions] Low throughput yes yes
HOME1_HUMAN [view entry] [view interactions] Low throughput yes yes
CRK_HUMAN [view entry] [view interactions] High throughput yes no
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
YAP1_HUMAN [view interactions] High throughput no yes
SMAD2_HUMAN [view interactions] High throughput no yes
SMAD3_HUMAN [view interactions] High throughput no yes
KIF11_HUMAN [view interactions] High throughput no yes
CRY1_HUMAN [view interactions] High throughput no yes
PCNA_HUMAN [view interactions] High throughput no no
DEN6A_HUMAN [view interactions] High throughput no yes
TMEDA_HUMAN [view interactions] High throughput no yes
PRSR2_HUMAN [view interactions] High throughput no yes
PALM2_HUMAN [view entry] [view interactions] High throughput yes no
DOK4_HUMAN [view interactions] High throughput no yes
PWP1_HUMAN [view interactions] High throughput no no
NEXN_HUMAN [view interactions] High throughput no yes
NCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
FEZ1_HUMAN [view interactions] High throughput no no
HIF1N_HUMAN [view interactions] High throughput no yes
JIP1_HUMAN [view entry] [view interactions] High throughput yes yes
IMP1L_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
HMGN1_HUMAN [view interactions] High throughput no yes
H1X_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
MICA3_HUMAN [view interactions] High throughput no yes
SPAT7_HUMAN [view interactions] High throughput no no
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
ITM2B_HUMAN [view interactions] High throughput no yes
MK06_HUMAN [view interactions] High throughput no yes
PICAL_HUMAN [view entry] [view interactions] High throughput yes yes
NDEL1_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
TMM17_HUMAN [view interactions] High throughput no yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
CTDSL_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
EPHB2_HUMAN [view entry] [view interactions] High throughput yes yes
FGFR1_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
PGFRA_HUMAN [view interactions] High throughput no no
NS1BP_HUMAN [view interactions] High throughput no yes
TF3C4_HUMAN [view interactions] High throughput no no
EP15R_HUMAN [view entry] [view interactions] High throughput yes yes
MCM6_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
MCM4_HUMAN [view interactions] High throughput no yes
JIP4_HUMAN [view interactions] High throughput no yes
UBP15_HUMAN [view entry] [view interactions] High throughput yes yes
NAB2_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
RING2_HUMAN [view interactions] High throughput no yes
PHAF1_HUMAN [view interactions] High throughput no yes
RPGF5_HUMAN [view interactions] High throughput no yes
UXS1_HUMAN [view interactions] High throughput no yes
LIRA6_HUMAN [view interactions] High throughput no no
RHG22_HUMAN [view entry] [view interactions] High throughput yes yes
AGAP2_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPL_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
AGRIN_HUMAN [view entry] [view interactions] High throughput yes yes
PLK1_HUMAN [view interactions] High throughput no yes
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
SCN1A_HUMAN [view interactions] High throughput no no
SCN2A_HUMAN [view entry] [view interactions] High throughput yes yes
SCN8A_HUMAN [view entry] [view interactions] High throughput yes no
CUL4A_HUMAN [view interactions] High throughput no no
PQBP1_HUMAN [view interactions] High throughput no yes
RYK_HUMAN [view interactions] High throughput no no
TTLL4_HUMAN [view interactions] High throughput no yes
FGF12_HUMAN [view interactions] High throughput no no
MYPT2_HUMAN [view interactions] High throughput no no
CCD96_HUMAN [view interactions] High throughput no no
ABTB2_HUMAN [view interactions] High throughput no yes
TTBK1_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
JIP2_HUMAN [view entry] [view interactions] High throughput yes no
BSND_HUMAN [view interactions] High throughput no no
AJUBA_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RND3_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
SRPK2_HUMAN [view entry] [view interactions] High throughput yes yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
AGR2_HUMAN [view interactions] High throughput no no
RET_HUMAN [view interactions] High throughput no yes
PTPRA_HUMAN [view interactions] High throughput no yes
DNJC5_HUMAN [view interactions] High throughput no yes
RHG21_HUMAN [view entry] [view interactions] High throughput yes yes
ARVC_HUMAN [view entry] [view interactions] High throughput yes yes
AT2B1_HUMAN [view entry] [view interactions] High throughput yes yes
BCR_HUMAN [view entry] [view interactions] High throughput yes yes
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
CTND1_HUMAN [view entry] [view interactions] High throughput yes no
DOCK7_HUMAN [view entry] [view interactions] High throughput yes no
DTNA_HUMAN [view entry] [view interactions] High throughput yes yes
FARP1_HUMAN [view entry] [view interactions] High throughput yes no
FCHO2_HUMAN [view interactions] High throughput no yes
LRCH3_HUMAN [view interactions] High throughput no yes
LZTS2_HUMAN [view interactions] High throughput no no
NAA35_HUMAN [view interactions] High throughput no yes
AKAP2_HUMAN [view interactions] High throughput no no
LIPB1_HUMAN [view interactions] High throughput no yes
SIR2_HUMAN [view entry] [view interactions] High throughput yes yes
SMRCD_HUMAN [view interactions] High throughput no yes
SPTN1_HUMAN [view entry] [view interactions] High throughput yes yes
SPTN2_HUMAN [view entry] [view interactions] High throughput yes yes
ABR_HUMAN [view entry] [view interactions] High throughput yes yes
ANR28_HUMAN [view interactions] High throughput no no
CE152_HUMAN [view interactions] High throughput no yes
DLG5_HUMAN [view entry] [view interactions] High throughput yes no
EIF3F_HUMAN [view interactions] High throughput no yes
H31_HUMAN [view interactions] High throughput no yes
SKT_HUMAN [view entry] [view interactions] High throughput yes yes
PEAK1_HUMAN [view interactions] High throughput no yes
CMC2_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
UTRN_HUMAN [view entry] [view interactions] High throughput yes yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
DIRA3_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
E41LA_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
LCK_HUMAN [view entry] [view interactions] High throughput yes no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
STX4_HUMAN [view entry] [view interactions] High throughput yes no
STX6_HUMAN [view interactions] High throughput no yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
ZFPL1_HUMAN [view interactions] High throughput no yes
VP33B_HUMAN [view interactions] High throughput no yes
RNF43_HUMAN [view interactions] High throughput no yes
CD44_HUMAN [view interactions] Computational no yes
ANK2_HUMAN [view entry] [view interactions] Computational yes yes
KCNQ2_HUMAN [view entry] [view interactions] Computational yes yes
SCN3A_HUMAN [view interactions] Computational no yes
NFASC_HUMAN [view entry] [view interactions] Computational yes yes
SPTN5_HUMAN [view interactions] Computational no no
MAGD1_HUMAN [view interactions] Computational no no
KCNQ3_HUMAN [view interactions] Computational no no
ITPR2_HUMAN [view interactions] Computational no yes
NAV1_HUMAN [view interactions] Computational no yes
SCNAA_HUMAN [view interactions] Computational no no
NRCAM_HUMAN [view entry] [view interactions] Computational yes no
ANK1_HUMAN [view entry] [view interactions] Computational yes no
ITPR3_HUMAN [view interactions] Computational no yes