AT1A1_HUMAN
Evidence for PS localization
Functions
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in AT1A1_HUMAN |
|---|---|---|---|---|
| GO:0032555 | purine ribonucleotide binding | 35.6643 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 35.6643 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 35.6643 | 4 | yes |
| GO:0046872 | metal ion binding | 26.5734 | 4 | yes |
| GO:0019900 | kinase binding | 21.6783 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.9790 | 5 | yes |
| GO:0005524 | ATP binding | 20.9790 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 20.9790 | 5 | yes |
| GO:0008324 | cation transmembrane transporter activity | 15.3846 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 14.6853 | 4 | yes |
| GO:0022853 | active ion transmembrane transporter activity | 12.5874 | 4 | yes |
| GO:0015399 | primary active transmembrane transporter activity | 11.1888 | 4 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 10.4895 | 5 | yes |
| GO:0015662 | P-type ion transporter activity | 6.9930 | 4 | yes |
| GO:0046982 | protein heterodimerization activity | 6.2937 | 4 | yes |
| GO:0015079 | potassium ion transmembrane transporter activity | 6.2937 | 6 | yes |
| GO:0015081 | sodium ion transmembrane transporter activity | 6.2937 | 6 | yes |
| GO:0005391 | P-type sodium:potassium-exchanging transporter activity | 4.8951 | 5 | yes |
| GO:0008554 | P-type sodium transporter activity | 4.8951 | 4 | yes |
| GO:0008556 | P-type potassium transmembrane transporter activity | 4.8951 | 4 | yes |
| GO:0042578 | phosphoric ester hydrolase activity | 3.4965 | 4 | yes |
| GO:0016791 | phosphatase activity | 3.4965 | 5 | yes |
| GO:0030955 | potassium ion binding | 2.7972 | 6 | yes |
| GO:0031420 | alkali metal ion binding | 2.7972 | 5 | yes |
| GO:0031402 | sodium ion binding | 2.0979 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in AT1A1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 53.8462 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 42.6573 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 41.9580 | 4 | yes |
| GO:0010646 | regulation of cell communication | 41.9580 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 40.5594 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 39.1608 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 38.4615 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 36.3636 | 4 | no |
| GO:0022607 | cellular component assembly | 34.9650 | 4 | no |
| GO:0009966 | regulation of signal transduction | 34.2657 | 4 | no |
| GO:0006996 | organelle organization | 33.5664 | 4 | no |
| GO:0051049 | regulation of transport | 32.1678 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 32.1678 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 31.4685 | 5 | no |
| GO:0010468 | regulation of gene expression | 30.7692 | 5 | no |
| GO:0008104 | protein localization | 27.9720 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 27.9720 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 27.2727 | 5 | no |
| GO:0071310 | cellular response to organic substance | 25.8741 | 4 | yes |
| GO:0071702 | organic substance transport | 25.1748 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 25.1748 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 24.4755 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 24.4755 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.4755 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 23.7762 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 23.7762 | 5 | yes |
| GO:0016192 | vesicle-mediated transport | 23.7762 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.7762 | 5 | no |
| GO:0071705 | nitrogen compound transport | 23.0769 | 4 | no |
| GO:0060341 | regulation of cellular localization | 23.0769 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 23.0769 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.0769 | 4 | no |
| GO:0010941 | regulation of cell death | 23.0769 | 4 | no |
| GO:0031399 | regulation of protein modification process | 23.0769 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 22.3776 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 22.3776 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 22.3776 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.3776 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.3776 | 6 | no |
| GO:0032880 | regulation of protein localization | 21.6783 | 5 | no |
| GO:0036211 | protein modification process | 21.6783 | 4 | no |
| GO:0043412 | macromolecule modification | 21.6783 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.9790 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 20.9790 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 20.9790 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 20.9790 | 5 | no |
| GO:0006811 | ion transport | 20.9790 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 20.2797 | 4 | no |
| GO:0048878 | chemical homeostasis | 19.5804 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 17.4825 | 5 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 17.4825 | 4 | yes |
| GO:0050801 | ion homeostasis | 16.7832 | 5 | yes |
| GO:0055080 | cation homeostasis | 16.7832 | 6 | yes |
| GO:0098771 | inorganic ion homeostasis | 16.7832 | 6 | yes |
| GO:0006812 | cation transport | 16.0839 | 5 | yes |
| GO:0043269 | regulation of ion transport | 16.0839 | 5 | yes |
| GO:0006873 | cellular ion homeostasis | 15.3846 | 4 | yes |
| GO:0030003 | cellular cation homeostasis | 15.3846 | 5 | yes |
| GO:0055065 | metal ion homeostasis | 14.6853 | 7 | yes |
| GO:0014070 | response to organic cyclic compound | 13.9860 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 13.9860 | 4 | yes |
| GO:0006875 | cellular metal ion homeostasis | 13.2867 | 6 | yes |
| GO:0030001 | metal ion transport | 13.2867 | 6 | yes |
| GO:0098655 | cation transmembrane transport | 12.5874 | 4 | yes |
| GO:0098660 | inorganic ion transmembrane transport | 12.5874 | 4 | yes |
| GO:0010959 | regulation of metal ion transport | 11.8881 | 6 | yes |
| GO:0044057 | regulation of system process | 11.8881 | 4 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 11.1888 | 5 | yes |
| GO:0098662 | inorganic cation transmembrane transport | 11.1888 | 5 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 9.7902 | 5 | yes |
| GO:0030004 | cellular monovalent inorganic cation homeostasis | 9.7902 | 6 | yes |
| GO:0055067 | monovalent inorganic cation homeostasis | 9.7902 | 7 | yes |
| GO:0033993 | response to lipid | 9.0909 | 4 | yes |
| GO:0098657 | import into cell | 9.0909 | 4 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 8.3916 | 6 | yes |
| GO:0071396 | cellular response to lipid | 8.3916 | 5 | yes |
| GO:0090257 | regulation of muscle system process | 8.3916 | 5 | yes |
| GO:0032870 | cellular response to hormone stimulus | 7.6923 | 4 | yes |
| GO:0006937 | regulation of muscle contraction | 6.9930 | 6 | yes |
| GO:0048545 | response to steroid hormone | 6.9930 | 4 | yes |
| GO:0098659 | inorganic cation import across plasma membrane | 6.9930 | 5 | yes |
| GO:0099587 | inorganic ion import across plasma membrane | 6.9930 | 4 | yes |
| GO:0002028 | regulation of sodium ion transport | 6.9930 | 7 | yes |
| GO:0006813 | potassium ion transport | 6.2937 | 7 | yes |
| GO:0006814 | sodium ion transport | 6.2937 | 7 | yes |
| GO:0006883 | cellular sodium ion homeostasis | 6.2937 | 7 | yes |
| GO:0030007 | cellular potassium ion homeostasis | 6.2937 | 7 | yes |
| GO:0035725 | sodium ion transmembrane transport | 6.2937 | 6 | yes |
| GO:0036376 | sodium ion export across plasma membrane | 6.2937 | 4 | yes |
| GO:0055075 | potassium ion homeostasis | 6.2937 | 8 | yes |
| GO:0055078 | sodium ion homeostasis | 6.2937 | 8 | yes |
| GO:1903522 | regulation of blood circulation | 6.2937 | 5 | yes |
| GO:0008016 | regulation of heart contraction | 5.5944 | 6 | yes |
| GO:0071383 | cellular response to steroid hormone stimulus | 5.5944 | 5 | yes |
| GO:0071805 | potassium ion transmembrane transport | 5.5944 | 6 | yes |
| GO:0086064 | cell communication by electrical coupling involved in cardiac conduction | 5.5944 | 4 | yes |
| GO:1902600 | proton transmembrane transport | 5.5944 | 6 | yes |
| GO:1990573 | potassium ion import across plasma membrane | 5.5944 | 6 | yes |
| GO:0019216 | regulation of lipid metabolic process | 4.8951 | 5 | yes |
| GO:0090075 | relaxation of muscle | 4.8951 | 4 | yes |
| GO:0006942 | regulation of striated muscle contraction | 4.1958 | 7 | yes |
| GO:0055119 | relaxation of cardiac muscle | 4.1958 | 5 | yes |
| GO:0086009 | membrane repolarization | 3.4965 | 4 | yes |
| GO:0045822 | negative regulation of heart contraction | 2.7972 | 6 | yes |
| GO:0045823 | positive regulation of heart contraction | 2.7972 | 6 | yes |
| GO:1903416 | response to glycoside | 2.7972 | 4 | yes |
| GO:1903523 | negative regulation of blood circulation | 2.7972 | 5 | yes |
| GO:1903524 | positive regulation of blood circulation | 2.7972 | 5 | yes |
| GO:0001508 | action potential | 2.7972 | 4 | yes |
| GO:0019218 | regulation of steroid metabolic process | 2.0979 | 6 | yes |
| GO:0045833 | negative regulation of lipid metabolic process | 2.0979 | 5 | yes |
| GO:0045933 | positive regulation of muscle contraction | 2.0979 | 5 | yes |
| GO:0046890 | regulation of lipid biosynthetic process | 2.0979 | 5 | yes |
| GO:0086001 | cardiac muscle cell action potential | 2.0979 | 5 | yes |
| GO:0086002 | cardiac muscle cell action potential involved in contraction | 2.0979 | 6 | yes |
| GO:0086011 | membrane repolarization during action potential | 2.0979 | 5 | yes |
| GO:0086013 | membrane repolarization during cardiac muscle cell action potential | 2.0979 | 6 | yes |
| GO:0099622 | cardiac muscle cell membrane repolarization | 2.0979 | 5 | yes |
| GO:0010894 | negative regulation of steroid biosynthetic process | 1.3986 | 7 | yes |
| GO:0031943 | regulation of glucocorticoid metabolic process | 1.3986 | 5 | yes |
| GO:0031944 | negative regulation of glucocorticoid metabolic process | 1.3986 | 6 | yes |
| GO:0031946 | regulation of glucocorticoid biosynthetic process | 1.3986 | 6 | yes |
| GO:0031947 | negative regulation of glucocorticoid biosynthetic process | 1.3986 | 7 | yes |
| GO:0032350 | regulation of hormone metabolic process | 1.3986 | 4 | yes |
| GO:0032351 | negative regulation of hormone metabolic process | 1.3986 | 5 | yes |
| GO:0032353 | negative regulation of hormone biosynthetic process | 1.3986 | 6 | yes |
| GO:0045939 | negative regulation of steroid metabolic process | 1.3986 | 6 | yes |
| GO:0045989 | positive regulation of striated muscle contraction | 1.3986 | 6 | yes |
| GO:0046885 | regulation of hormone biosynthetic process | 1.3986 | 5 | yes |
| GO:0050810 | regulation of steroid biosynthetic process | 1.3986 | 6 | yes |
| GO:0051055 | negative regulation of lipid biosynthetic process | 1.3986 | 6 | yes |
| GO:0090030 | regulation of steroid hormone biosynthetic process | 1.3986 | 6 | yes |
| GO:0090032 | negative regulation of steroid hormone biosynthetic process | 1.3986 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in AT1A1_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 1.3986 | 3 | no |
| DOID:1289 | neurodegenerative disease | 1.3986 | 4 | no |
| DOID:331 | central nervous system disease | 1.3986 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GPNMB_HUMAN | [view interactions] | Low throughput | no | no |
| RN183_HUMAN | [view interactions] | Low throughput | no | no |
| TCTP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AT1B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| FXYD3_HUMAN | [view interactions] | Low throughput | no | yes |
| KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZNRF1_HUMAN | [view interactions] | Low throughput | no | yes |
| ZNRF2_HUMAN | [view interactions] | Low throughput | no | yes |
| PKD1_HUMAN | [view interactions] | Low throughput | no | yes |
| PKD2_HUMAN | [view interactions] | Low throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNX6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CAC1D_HUMAN | [view interactions] | Low throughput | no | yes |
| KLOT_HUMAN | [view interactions] | Low throughput | no | no |
| B3AT_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PPME1_HUMAN | [view interactions] | Low throughput | no | yes |
| S12A1_HUMAN | [view interactions] | Low throughput | no | no |
| COF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PLM_HUMAN | [view interactions] | Low throughput | no | no |
| FXYD7_HUMAN | [view interactions] | Low throughput | no | no |
| NAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FXYD4_HUMAN | [view interactions] | Low throughput | no | no |
| AP2A2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| HAVR1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXNIP_HUMAN | [view interactions] | High throughput | no | no |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| MFRN2_HUMAN | [view interactions] | High throughput | no | no |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| TRPC6_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| NFIX_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| SOX17_HUMAN | [view interactions] | High throughput | no | no |
| INSI1_HUMAN | [view interactions] | High throughput | no | no |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| RN185_HUMAN | [view interactions] | High throughput | no | no |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| AGO1_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMK2_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| MUL1_HUMAN | [view interactions] | High throughput | no | no |
| TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JPH1_HUMAN | [view interactions] | High throughput | no | no |
| BMR1A_HUMAN | [view interactions] | High throughput | no | no |
| FOXK2_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NICA_HUMAN | [view interactions] | High throughput | no | yes |
| OMA1_HUMAN | [view interactions] | High throughput | no | no |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| FOXK1_HUMAN | [view interactions] | High throughput | no | yes |
| MBOA1_HUMAN | [view interactions] | High throughput | no | no |
| DOP2_HUMAN | [view interactions] | High throughput | no | yes |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| SPP2B_HUMAN | [view interactions] | High throughput | no | yes |
| YIPF5_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| CSCL2_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| ZN363_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| CD9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TSN5_HUMAN | [view interactions] | High throughput | no | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TSN15_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| MK07_HUMAN | [view interactions] | High throughput | no | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PEBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| NDRG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF4_HUMAN | [view interactions] | High throughput | no | yes |
| 4F2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| LAT1_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| NCK5L_HUMAN | [view interactions] | High throughput | no | yes |
| F241A_HUMAN | [view interactions] | High throughput | no | yes |
| B4GT2_HUMAN | [view interactions] | High throughput | no | no |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| AL7A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADAT2_HUMAN | [view interactions] | High throughput | no | yes |
| ZFHX4_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM27_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| RT11_HUMAN | [view interactions] | High throughput | no | yes |
| E2F3_HUMAN | [view interactions] | High throughput | no | no |
| RT14_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| MZT1_HUMAN | [view interactions] | High throughput | no | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB2_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLP1_HUMAN | [view interactions] | High throughput | no | no |
| GRK6_HUMAN | [view interactions] | High throughput | no | yes |
| TCOF_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| ZN574_HUMAN | [view interactions] | High throughput | no | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| STYK1_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADCK2_HUMAN | [view interactions] | High throughput | no | yes |
| ST32C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| PMYT1_HUMAN | [view interactions] | High throughput | no | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| ACADM_HUMAN | [view interactions] | High throughput | no | yes |
| NDRG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1B2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAMP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| CLH2_HUMAN | [view interactions] | High throughput | no | no |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RD3_HUMAN | [view interactions] | High throughput | no | no |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD177_HUMAN | [view interactions] | High throughput | no | no |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPR35_HUMAN | [view interactions] | High throughput | no | no |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR1B_HUMAN | [view interactions] | High throughput | no | no |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRADD_HUMAN | [view interactions] | High throughput | no | yes |
| OST48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3B_HUMAN | [view interactions] | High throughput | no | yes |
| MK04_HUMAN | [view interactions] | High throughput | no | no |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK20_HUMAN | [view interactions] | High throughput | no | yes |
| ITA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HIPK4_HUMAN | [view interactions] | High throughput | no | no |
| RM40_HUMAN | [view interactions] | High throughput | no | yes |
| DYRK4_HUMAN | [view interactions] | High throughput | no | no |
| NDUB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD3_HUMAN | [view interactions] | High throughput | no | yes |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSRB_HUMAN | [view interactions] | High throughput | no | no |
| RAB4B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TECR_HUMAN | [view interactions] | High throughput | no | yes |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| TMCO1_HUMAN | [view interactions] | High throughput | no | yes |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPCAM_HUMAN | [view interactions] | High throughput | no | no |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC5A1_HUMAN | [view interactions] | High throughput | no | no |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTS_HUMAN | [view interactions] | High throughput | no | no |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2FB_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD2_HUMAN | [view interactions] | High throughput | no | yes |
| ARMX3_HUMAN | [view interactions] | High throughput | no | no |
| TECT3_HUMAN | [view interactions] | High throughput | no | yes |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM5_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| FHI1A_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| PTN1_HUMAN | [view interactions] | High throughput | no | yes |
| A2MG_HUMAN | [view interactions] | High throughput | no | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| NELFB_HUMAN | [view interactions] | High throughput | no | no |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| NELFD_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| NELFA_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| P5F1B_HUMAN | [view interactions] | High throughput | no | no |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX25_HUMAN | [view interactions] | High throughput | no | no |
| DYR2_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| APH1A_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| APH1B_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| CLN3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| MET7A_HUMAN | [view interactions] | High throughput | no | no |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SKI_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| ABCG1_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| NEPRO_HUMAN | [view interactions] | High throughput | no | no |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCDN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| DPOD1_HUMAN | [view interactions] | High throughput | no | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| TXTP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PURA2_HUMAN | [view interactions] | High throughput | no | yes |
| COPE_HUMAN | [view interactions] | High throughput | no | yes |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2L6_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| ATP4B_HUMAN | [view interactions] | Computational | no | no |
| AT2A2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ATNG_HUMAN | [view interactions] | Computational | no | no |
| AT1B4_HUMAN | [view interactions] | Computational | no | no |
| AT1A4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| KCNJ5_HUMAN | [view interactions] | Computational | no | yes |
| SL9A1_HUMAN | [view interactions] | Computational | no | no |
| XLRS1_HUMAN | [view interactions] | Computational | no | no |