Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

AT1B2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in AT1B2_HUMAN
GO:0046872 metal ion binding 44.4444 4 no
GO:0003723 RNA binding 38.8889 4 no
GO:0008324 cation transmembrane transporter activity 38.8889 4 no
GO:0015399 primary active transmembrane transporter activity 38.8889 4 no
GO:0015662 P-type ion transporter activity 38.8889 4 no
GO:0022853 active ion transmembrane transporter activity 38.8889 4 no
GO:0022890 inorganic cation transmembrane transporter activity 38.8889 4 no
GO:0046873 metal ion transmembrane transporter activity 38.8889 5 no
GO:0005524 ATP binding 33.3333 5 no
GO:0017076 purine nucleotide binding 33.3333 4 no
GO:0030554 adenyl nucleotide binding 33.3333 5 no
GO:0032555 purine ribonucleotide binding 33.3333 4 no
GO:0032559 adenyl ribonucleotide binding 33.3333 5 no
GO:0035639 purine ribonucleoside triphosphate binding 33.3333 4 no
GO:0005391 P-type sodium:potassium-exchanging transporter activity 33.3333 5 no
GO:0008554 P-type sodium transporter activity 33.3333 4 no
GO:0008556 P-type potassium transmembrane transporter activity 33.3333 4 no
GO:0015079 potassium ion transmembrane transporter activity 33.3333 6 no
GO:0015081 sodium ion transmembrane transporter activity 33.3333 6 no
GO:0046982 protein heterodimerization activity 22.2222 4 yes
GO:0019900 kinase binding 22.2222 4 no
GO:0051117 ATPase binding 11.1111 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in AT1B2_HUMAN
GO:0048523 negative regulation of cellular process 50.0000 4 yes
GO:0048878 chemical homeostasis 50.0000 4 yes
GO:0006811 ion transport 44.4444 4 yes
GO:0006812 cation transport 44.4444 5 yes
GO:0006873 cellular ion homeostasis 44.4444 4 yes
GO:0006875 cellular metal ion homeostasis 44.4444 6 yes
GO:0030001 metal ion transport 44.4444 6 yes
GO:0030003 cellular cation homeostasis 44.4444 5 yes
GO:0050801 ion homeostasis 44.4444 5 yes
GO:0055065 metal ion homeostasis 44.4444 7 yes
GO:0055080 cation homeostasis 44.4444 6 yes
GO:0098655 cation transmembrane transport 44.4444 4 yes
GO:0098660 inorganic ion transmembrane transport 44.4444 4 yes
GO:0098662 inorganic cation transmembrane transport 44.4444 5 yes
GO:0098771 inorganic ion homeostasis 44.4444 6 yes
GO:0006813 potassium ion transport 38.8889 7 yes
GO:0006814 sodium ion transport 38.8889 7 yes
GO:0006883 cellular sodium ion homeostasis 38.8889 7 yes
GO:0030004 cellular monovalent inorganic cation homeostasis 38.8889 6 yes
GO:0030007 cellular potassium ion homeostasis 38.8889 7 yes
GO:0035725 sodium ion transmembrane transport 38.8889 6 yes
GO:0036376 sodium ion export across plasma membrane 38.8889 4 yes
GO:0048522 positive regulation of cellular process 38.8889 4 yes
GO:0051049 regulation of transport 38.8889 4 yes
GO:0055067 monovalent inorganic cation homeostasis 38.8889 7 yes
GO:0055075 potassium ion homeostasis 38.8889 8 yes
GO:0055078 sodium ion homeostasis 38.8889 8 yes
GO:0071805 potassium ion transmembrane transport 38.8889 6 yes
GO:0098657 import into cell 38.8889 4 yes
GO:0098659 inorganic cation import across plasma membrane 38.8889 5 yes
GO:0099587 inorganic ion import across plasma membrane 38.8889 4 yes
GO:1990573 potassium ion import across plasma membrane 38.8889 6 yes
GO:0010646 regulation of cell communication 38.8889 4 no
GO:0030030 cell projection organization 33.3333 4 yes
GO:0043269 regulation of ion transport 33.3333 5 yes
GO:0120036 plasma membrane bounded cell projection organization 33.3333 5 yes
GO:0044057 regulation of system process 33.3333 4 no
GO:0051240 positive regulation of multicellular organismal process 33.3333 4 no
GO:0031323 regulation of cellular metabolic process 33.3333 4 no
GO:0060255 regulation of macromolecule metabolic process 33.3333 4 no
GO:0080090 regulation of primary metabolic process 33.3333 4 no
GO:0022898 regulation of transmembrane transporter activity 27.7778 4 yes
GO:0031344 regulation of cell projection organization 27.7778 5 yes
GO:0032412 regulation of ion transmembrane transporter activity 27.7778 5 yes
GO:0034762 regulation of transmembrane transport 27.7778 4 yes
GO:0034765 regulation of ion transmembrane transport 27.7778 5 yes
GO:0051128 regulation of cellular component organization 27.7778 4 yes
GO:0086064 cell communication by electrical coupling involved in cardiac conduction 27.7778 4 yes
GO:1904062 regulation of cation transmembrane transport 27.7778 6 yes
GO:0006996 organelle organization 27.7778 4 no
GO:0022607 cellular component assembly 27.7778 4 no
GO:0050804 modulation of chemical synaptic transmission 27.7778 5 no
GO:0099177 regulation of trans-synaptic signaling 27.7778 4 no
GO:0008104 protein localization 27.7778 4 no
GO:0009966 regulation of signal transduction 27.7778 4 no
GO:0051171 regulation of nitrogen compound metabolic process 27.7778 4 no
GO:0051246 regulation of protein metabolic process 27.7778 5 no
GO:0010468 regulation of gene expression 27.7778 5 no
GO:0071310 cellular response to organic substance 27.7778 4 no
GO:1902600 proton transmembrane transport 27.7778 6 no
GO:0002028 regulation of sodium ion transport 22.2222 7 yes
GO:0010959 regulation of metal ion transport 22.2222 6 yes
GO:0010975 regulation of neuron projection development 22.2222 7 yes
GO:0051130 positive regulation of cellular component organization 22.2222 5 yes
GO:0086009 membrane repolarization 22.2222 4 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 22.2222 6 yes
GO:0006412 translation 22.2222 4 no
GO:0006518 peptide metabolic process 22.2222 4 no
GO:0009059 macromolecule biosynthetic process 22.2222 4 no
GO:0034645 cellular macromolecule biosynthetic process 22.2222 4 no
GO:0043043 peptide biosynthetic process 22.2222 5 no
GO:0043603 cellular amide metabolic process 22.2222 4 no
GO:0043604 amide biosynthetic process 22.2222 5 no
GO:0044271 cellular nitrogen compound biosynthetic process 22.2222 4 no
GO:1901566 organonitrogen compound biosynthetic process 22.2222 4 no
GO:0006937 regulation of muscle contraction 22.2222 6 no
GO:0006942 regulation of striated muscle contraction 22.2222 7 no
GO:0008016 regulation of heart contraction 22.2222 6 no
GO:0051241 negative regulation of multicellular organismal process 22.2222 4 no
GO:0055119 relaxation of cardiac muscle 22.2222 5 no
GO:0090075 relaxation of muscle 22.2222 4 no
GO:0090257 regulation of muscle system process 22.2222 5 no
GO:1903522 regulation of blood circulation 22.2222 5 no
GO:0009893 positive regulation of metabolic process 22.2222 4 no
GO:0009967 positive regulation of signal transduction 22.2222 5 no
GO:0010604 positive regulation of macromolecule metabolic process 22.2222 5 no
GO:0010647 positive regulation of cell communication 22.2222 5 no
GO:0022603 regulation of anatomical structure morphogenesis 22.2222 4 no
GO:0023056 positive regulation of signaling 22.2222 4 no
GO:0031175 neuron projection development 22.2222 6 no
GO:0048584 positive regulation of response to stimulus 22.2222 4 no
GO:0050890 cognition 22.2222 4 no
GO:0051094 positive regulation of developmental process 22.2222 4 no
GO:0051129 negative regulation of cellular component organization 22.2222 5 no
GO:0009892 negative regulation of metabolic process 22.2222 4 no
GO:0031324 negative regulation of cellular metabolic process 22.2222 5 no
GO:0032870 cellular response to hormone stimulus 22.2222 4 no
GO:0003018 vascular process in circulatory system 16.6667 4 yes
GO:0010232 vascular transport 16.6667 4 yes
GO:0031346 positive regulation of cell projection organization 16.6667 6 yes
GO:0032411 positive regulation of transporter activity 16.6667 4 yes
GO:0032414 positive regulation of ion transmembrane transporter activity 16.6667 5 yes
GO:0034764 positive regulation of transmembrane transport 16.6667 5 yes
GO:0034767 positive regulation of ion transmembrane transport 16.6667 6 yes
GO:0043270 positive regulation of ion transport 16.6667 5 yes
GO:0050821 protein stabilization 16.6667 4 yes
GO:0051050 positive regulation of transport 16.6667 4 yes
GO:0150104 transport across blood-brain barrier 16.6667 5 yes
GO:1902305 regulation of sodium ion transmembrane transport 16.6667 7 yes
GO:1904064 positive regulation of cation transmembrane transport 16.6667 7 yes
GO:0010765 positive regulation of sodium ion transport 11.1111 6 yes
GO:0030334 regulation of cell migration 11.1111 5 yes
GO:0032781 positive regulation of ATP-dependent activity 11.1111 4 yes
GO:0043266 regulation of potassium ion transport 11.1111 7 yes
GO:0043268 positive regulation of potassium ion transport 11.1111 6 yes
GO:1901016 regulation of potassium ion transmembrane transporter activity 11.1111 6 yes
GO:1901018 positive regulation of potassium ion transmembrane transporter activity 11.1111 6 yes
GO:1901379 regulation of potassium ion transmembrane transport 11.1111 7 yes
GO:1901381 positive regulation of potassium ion transmembrane transport 11.1111 7 yes
GO:1902307 positive regulation of sodium ion transmembrane transport 11.1111 7 yes
GO:1903276 regulation of sodium ion export across plasma membrane 11.1111 8 yes
GO:1903278 positive regulation of sodium ion export across plasma membrane 11.1111 8 yes
GO:1903286 regulation of potassium ion import 11.1111 8 yes
GO:1903288 positive regulation of potassium ion import across plasma membrane 11.1111 8 yes
GO:2000145 regulation of cell motility 11.1111 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
APBB1_HUMAN [view interactions] High throughput no yes
XLRS1_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
CPEB2_HUMAN [view entry] [view interactions] High throughput yes no
COPG2_HUMAN [view interactions] High throughput no yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
TADBP_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
GNMT_HUMAN [view interactions] High throughput no no
AT1A3_HUMAN [view entry] [view interactions] High throughput yes no
TSN31_HUMAN [view interactions] High throughput no yes
CLGN_HUMAN [view interactions] High throughput no no
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
AT5F1_HUMAN [view interactions] High throughput no yes
RL26_HUMAN [view entry] [view interactions] High throughput yes yes
RLA2_HUMAN [view entry] [view interactions] High throughput yes yes
RS18_HUMAN [view entry] [view interactions] High throughput yes yes
RS8_HUMAN [view entry] [view interactions] High throughput yes no
AT1A2_HUMAN [view entry] [view interactions] High throughput yes yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
NGB_HUMAN [view interactions] High throughput no yes
AT1A4_HUMAN [view entry] [view interactions] Computational yes no
AT1B4_HUMAN [view interactions] Computational no no
RAB28_HUMAN [view interactions] Computational no yes
ATNG_HUMAN [view interactions] Computational no no
AT2A2_HUMAN [view entry] [view interactions] Computational yes yes
AT12A_HUMAN [view entry] [view interactions] Computational yes no
PLM_HUMAN [view interactions] Computational no no
AT1B3_HUMAN [view interactions] Computational no yes