AT1B2_HUMAN
Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth. [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in AT1B2_HUMAN |
---|---|---|---|---|
GO:0046872 | metal ion binding | 44.4444 | 4 | no |
GO:0003723 | RNA binding | 38.8889 | 4 | no |
GO:0008324 | cation transmembrane transporter activity | 38.8889 | 4 | no |
GO:0015399 | primary active transmembrane transporter activity | 38.8889 | 4 | no |
GO:0015662 | P-type ion transporter activity | 38.8889 | 4 | no |
GO:0022853 | active ion transmembrane transporter activity | 38.8889 | 4 | no |
GO:0022890 | inorganic cation transmembrane transporter activity | 38.8889 | 4 | no |
GO:0046873 | metal ion transmembrane transporter activity | 38.8889 | 5 | no |
GO:0005524 | ATP binding | 33.3333 | 5 | no |
GO:0017076 | purine nucleotide binding | 33.3333 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 33.3333 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 33.3333 | 4 | no |
GO:0032559 | adenyl ribonucleotide binding | 33.3333 | 5 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 33.3333 | 4 | no |
GO:0005391 | P-type sodium:potassium-exchanging transporter activity | 33.3333 | 5 | no |
GO:0008554 | P-type sodium transporter activity | 33.3333 | 4 | no |
GO:0008556 | P-type potassium transmembrane transporter activity | 33.3333 | 4 | no |
GO:0015079 | potassium ion transmembrane transporter activity | 33.3333 | 6 | no |
GO:0015081 | sodium ion transmembrane transporter activity | 33.3333 | 6 | no |
GO:0046982 | protein heterodimerization activity | 22.2222 | 4 | yes |
GO:0019900 | kinase binding | 22.2222 | 4 | no |
GO:0051117 | ATPase binding | 11.1111 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in AT1B2_HUMAN |
---|---|---|---|---|
GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | yes |
GO:0048878 | chemical homeostasis | 50.0000 | 4 | yes |
GO:0006811 | ion transport | 44.4444 | 4 | yes |
GO:0006812 | cation transport | 44.4444 | 5 | yes |
GO:0006873 | cellular ion homeostasis | 44.4444 | 4 | yes |
GO:0006875 | cellular metal ion homeostasis | 44.4444 | 6 | yes |
GO:0030001 | metal ion transport | 44.4444 | 6 | yes |
GO:0030003 | cellular cation homeostasis | 44.4444 | 5 | yes |
GO:0050801 | ion homeostasis | 44.4444 | 5 | yes |
GO:0055065 | metal ion homeostasis | 44.4444 | 7 | yes |
GO:0055080 | cation homeostasis | 44.4444 | 6 | yes |
GO:0098655 | cation transmembrane transport | 44.4444 | 4 | yes |
GO:0098660 | inorganic ion transmembrane transport | 44.4444 | 4 | yes |
GO:0098662 | inorganic cation transmembrane transport | 44.4444 | 5 | yes |
GO:0098771 | inorganic ion homeostasis | 44.4444 | 6 | yes |
GO:0006813 | potassium ion transport | 38.8889 | 7 | yes |
GO:0006814 | sodium ion transport | 38.8889 | 7 | yes |
GO:0006883 | cellular sodium ion homeostasis | 38.8889 | 7 | yes |
GO:0030004 | cellular monovalent inorganic cation homeostasis | 38.8889 | 6 | yes |
GO:0030007 | cellular potassium ion homeostasis | 38.8889 | 7 | yes |
GO:0035725 | sodium ion transmembrane transport | 38.8889 | 6 | yes |
GO:0036376 | sodium ion export across plasma membrane | 38.8889 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 38.8889 | 4 | yes |
GO:0051049 | regulation of transport | 38.8889 | 4 | yes |
GO:0055067 | monovalent inorganic cation homeostasis | 38.8889 | 7 | yes |
GO:0055075 | potassium ion homeostasis | 38.8889 | 8 | yes |
GO:0055078 | sodium ion homeostasis | 38.8889 | 8 | yes |
GO:0071805 | potassium ion transmembrane transport | 38.8889 | 6 | yes |
GO:0098657 | import into cell | 38.8889 | 4 | yes |
GO:0098659 | inorganic cation import across plasma membrane | 38.8889 | 5 | yes |
GO:0099587 | inorganic ion import across plasma membrane | 38.8889 | 4 | yes |
GO:1990573 | potassium ion import across plasma membrane | 38.8889 | 6 | yes |
GO:0010646 | regulation of cell communication | 38.8889 | 4 | no |
GO:0030030 | cell projection organization | 33.3333 | 4 | yes |
GO:0043269 | regulation of ion transport | 33.3333 | 5 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 33.3333 | 5 | yes |
GO:0044057 | regulation of system process | 33.3333 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 33.3333 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 33.3333 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 33.3333 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 33.3333 | 4 | no |
GO:0022898 | regulation of transmembrane transporter activity | 27.7778 | 4 | yes |
GO:0031344 | regulation of cell projection organization | 27.7778 | 5 | yes |
GO:0032412 | regulation of ion transmembrane transporter activity | 27.7778 | 5 | yes |
GO:0034762 | regulation of transmembrane transport | 27.7778 | 4 | yes |
GO:0034765 | regulation of ion transmembrane transport | 27.7778 | 5 | yes |
GO:0051128 | regulation of cellular component organization | 27.7778 | 4 | yes |
GO:0086064 | cell communication by electrical coupling involved in cardiac conduction | 27.7778 | 4 | yes |
GO:1904062 | regulation of cation transmembrane transport | 27.7778 | 6 | yes |
GO:0006996 | organelle organization | 27.7778 | 4 | no |
GO:0022607 | cellular component assembly | 27.7778 | 4 | no |
GO:0050804 | modulation of chemical synaptic transmission | 27.7778 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 27.7778 | 4 | no |
GO:0008104 | protein localization | 27.7778 | 4 | no |
GO:0009966 | regulation of signal transduction | 27.7778 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 27.7778 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 27.7778 | 5 | no |
GO:0010468 | regulation of gene expression | 27.7778 | 5 | no |
GO:0071310 | cellular response to organic substance | 27.7778 | 4 | no |
GO:1902600 | proton transmembrane transport | 27.7778 | 6 | no |
GO:0002028 | regulation of sodium ion transport | 22.2222 | 7 | yes |
GO:0010959 | regulation of metal ion transport | 22.2222 | 6 | yes |
GO:0010975 | regulation of neuron projection development | 22.2222 | 7 | yes |
GO:0051130 | positive regulation of cellular component organization | 22.2222 | 5 | yes |
GO:0086009 | membrane repolarization | 22.2222 | 4 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.2222 | 6 | yes |
GO:0006412 | translation | 22.2222 | 4 | no |
GO:0006518 | peptide metabolic process | 22.2222 | 4 | no |
GO:0009059 | macromolecule biosynthetic process | 22.2222 | 4 | no |
GO:0034645 | cellular macromolecule biosynthetic process | 22.2222 | 4 | no |
GO:0043043 | peptide biosynthetic process | 22.2222 | 5 | no |
GO:0043603 | cellular amide metabolic process | 22.2222 | 4 | no |
GO:0043604 | amide biosynthetic process | 22.2222 | 5 | no |
GO:0044271 | cellular nitrogen compound biosynthetic process | 22.2222 | 4 | no |
GO:1901566 | organonitrogen compound biosynthetic process | 22.2222 | 4 | no |
GO:0006937 | regulation of muscle contraction | 22.2222 | 6 | no |
GO:0006942 | regulation of striated muscle contraction | 22.2222 | 7 | no |
GO:0008016 | regulation of heart contraction | 22.2222 | 6 | no |
GO:0051241 | negative regulation of multicellular organismal process | 22.2222 | 4 | no |
GO:0055119 | relaxation of cardiac muscle | 22.2222 | 5 | no |
GO:0090075 | relaxation of muscle | 22.2222 | 4 | no |
GO:0090257 | regulation of muscle system process | 22.2222 | 5 | no |
GO:1903522 | regulation of blood circulation | 22.2222 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 22.2222 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 22.2222 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 22.2222 | 5 | no |
GO:0010647 | positive regulation of cell communication | 22.2222 | 5 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 22.2222 | 4 | no |
GO:0023056 | positive regulation of signaling | 22.2222 | 4 | no |
GO:0031175 | neuron projection development | 22.2222 | 6 | no |
GO:0048584 | positive regulation of response to stimulus | 22.2222 | 4 | no |
GO:0050890 | cognition | 22.2222 | 4 | no |
GO:0051094 | positive regulation of developmental process | 22.2222 | 4 | no |
GO:0051129 | negative regulation of cellular component organization | 22.2222 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 22.2222 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 22.2222 | 5 | no |
GO:0032870 | cellular response to hormone stimulus | 22.2222 | 4 | no |
GO:0003018 | vascular process in circulatory system | 16.6667 | 4 | yes |
GO:0010232 | vascular transport | 16.6667 | 4 | yes |
GO:0031346 | positive regulation of cell projection organization | 16.6667 | 6 | yes |
GO:0032411 | positive regulation of transporter activity | 16.6667 | 4 | yes |
GO:0032414 | positive regulation of ion transmembrane transporter activity | 16.6667 | 5 | yes |
GO:0034764 | positive regulation of transmembrane transport | 16.6667 | 5 | yes |
GO:0034767 | positive regulation of ion transmembrane transport | 16.6667 | 6 | yes |
GO:0043270 | positive regulation of ion transport | 16.6667 | 5 | yes |
GO:0050821 | protein stabilization | 16.6667 | 4 | yes |
GO:0051050 | positive regulation of transport | 16.6667 | 4 | yes |
GO:0150104 | transport across blood-brain barrier | 16.6667 | 5 | yes |
GO:1902305 | regulation of sodium ion transmembrane transport | 16.6667 | 7 | yes |
GO:1904064 | positive regulation of cation transmembrane transport | 16.6667 | 7 | yes |
GO:0010765 | positive regulation of sodium ion transport | 11.1111 | 6 | yes |
GO:0030334 | regulation of cell migration | 11.1111 | 5 | yes |
GO:0032781 | positive regulation of ATP-dependent activity | 11.1111 | 4 | yes |
GO:0043266 | regulation of potassium ion transport | 11.1111 | 7 | yes |
GO:0043268 | positive regulation of potassium ion transport | 11.1111 | 6 | yes |
GO:1901016 | regulation of potassium ion transmembrane transporter activity | 11.1111 | 6 | yes |
GO:1901018 | positive regulation of potassium ion transmembrane transporter activity | 11.1111 | 6 | yes |
GO:1901379 | regulation of potassium ion transmembrane transport | 11.1111 | 7 | yes |
GO:1901381 | positive regulation of potassium ion transmembrane transport | 11.1111 | 7 | yes |
GO:1902307 | positive regulation of sodium ion transmembrane transport | 11.1111 | 7 | yes |
GO:1903276 | regulation of sodium ion export across plasma membrane | 11.1111 | 8 | yes |
GO:1903278 | positive regulation of sodium ion export across plasma membrane | 11.1111 | 8 | yes |
GO:1903286 | regulation of potassium ion import | 11.1111 | 8 | yes |
GO:1903288 | positive regulation of potassium ion import across plasma membrane | 11.1111 | 8 | yes |
GO:2000145 | regulation of cell motility | 11.1111 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
APBB1_HUMAN | [view interactions] | High throughput | no | yes |
XLRS1_HUMAN | [view interactions] | High throughput | no | no |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
CPEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
COPG2_HUMAN | [view interactions] | High throughput | no | yes |
RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TADBP_HUMAN | [view interactions] | High throughput | no | yes |
TIA1_HUMAN | [view interactions] | High throughput | no | no |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GNMT_HUMAN | [view interactions] | High throughput | no | no |
AT1A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TSN31_HUMAN | [view interactions] | High throughput | no | yes |
CLGN_HUMAN | [view interactions] | High throughput | no | no |
CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
RL26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RLA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AT1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NGB_HUMAN | [view interactions] | High throughput | no | yes |
AT1A4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
AT1B4_HUMAN | [view interactions] | Computational | no | no |
RAB28_HUMAN | [view interactions] | Computational | no | yes |
ATNG_HUMAN | [view interactions] | Computational | no | no |
AT2A2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
AT12A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PLM_HUMAN | [view interactions] | Computational | no | no |
AT1B3_HUMAN | [view interactions] | Computational | no | yes |