CPEB2_HUMAN
Evidence for PS localization
Functions
May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers . Required for cell cycle progression, specifically for the transition from metaphase to anaphase (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CPEB2_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 40.0000 | 4 | yes |
| GO:0003729 | mRNA binding | 30.0000 | 5 | yes |
| GO:0043022 | ribosome binding | 30.0000 | 4 | yes |
| GO:0045296 | cadherin binding | 30.0000 | 4 | no |
| GO:0043169 | cation binding | 30.0000 | 4 | no |
| GO:0046872 | metal ion binding | 30.0000 | 5 | no |
| GO:0000166 | nucleotide binding | 30.0000 | 4 | no |
| GO:0005525 | GTP binding | 30.0000 | 5 | no |
| GO:0017076 | purine nucleotide binding | 30.0000 | 5 | no |
| GO:0019001 | guanyl nucleotide binding | 30.0000 | 6 | no |
| GO:0032555 | purine ribonucleotide binding | 30.0000 | 4 | no |
| GO:0032561 | guanyl ribonucleotide binding | 30.0000 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 30.0000 | 4 | no |
| GO:0043168 | anion binding | 30.0000 | 4 | no |
| GO:0046982 | protein heterodimerization activity | 30.0000 | 4 | no |
| GO:0003730 | mRNA 3-UTR binding | 20.0000 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CPEB2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 70.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 50.0000 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 50.0000 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 50.0000 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 40.0000 | 6 | yes |
| GO:0051246 | regulation of protein metabolic process | 40.0000 | 5 | yes |
| GO:0030030 | cell projection organization | 40.0000 | 4 | no |
| GO:0051049 | regulation of transport | 40.0000 | 4 | no |
| GO:0006417 | regulation of translation | 30.0000 | 6 | yes |
| GO:0010608 | post-transcriptional regulation of gene expression | 30.0000 | 7 | yes |
| GO:0006996 | organelle organization | 30.0000 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 30.0000 | 5 | no |
| GO:0031346 | positive regulation of cell projection organization | 30.0000 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 30.0000 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 30.0000 | 6 | no |
| GO:0009059 | macromolecule biosynthetic process | 30.0000 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 20.0000 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 20.0000 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 20.0000 | 4 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 20.0000 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.0000 | 5 | yes |
| GO:0010629 | negative regulation of gene expression | 20.0000 | 7 | yes |
| GO:0017148 | negative regulation of translation | 20.0000 | 7 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 20.0000 | 5 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 20.0000 | 6 | yes |
| GO:0036293 | response to decreased oxygen levels | 20.0000 | 4 | yes |
| GO:0036294 | cellular response to decreased oxygen levels | 20.0000 | 5 | yes |
| GO:0043087 | regulation of GTPase activity | 20.0000 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 20.0000 | 6 | yes |
| GO:0051336 | regulation of hydrolase activity | 20.0000 | 4 | yes |
| GO:0071453 | cellular response to oxygen levels | 20.0000 | 4 | yes |
| GO:2000765 | regulation of cytoplasmic translation | 20.0000 | 7 | yes |
| GO:2000766 | negative regulation of cytoplasmic translation | 20.0000 | 8 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| EF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| GPX7_HUMAN | [view interactions] | Low throughput | no | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| ATG2A_HUMAN | [view interactions] | High throughput | no | yes |
| ATP6_HUMAN | [view interactions] | High throughput | no | no |
| CSN7A_HUMAN | [view interactions] | High throughput | no | yes |
| GABR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYAG_HUMAN | [view interactions] | High throughput | no | yes |
| KEAP1_HUMAN | [view interactions] | High throughput | no | yes |
| AT1B2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NECA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| PIGS_HUMAN | [view interactions] | High throughput | no | yes |
| PUF60_HUMAN | [view interactions] | High throughput | no | yes |
| ERI3_HUMAN | [view interactions] | High throughput | no | yes |
| SAP_HUMAN | [view interactions] | High throughput | no | yes |
| SPRC_HUMAN | [view interactions] | High throughput | no | yes |
| BSCL2_HUMAN | [view interactions] | High throughput | no | yes |
| CAN15_HUMAN | [view interactions] | High throughput | no | yes |
| VINEX_HUMAN | [view interactions] | High throughput | no | no |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C2C2L_HUMAN | [view interactions] | High throughput | no | yes |
| RBPMS_HUMAN | [view interactions] | High throughput | no | no |
| DMRTB_HUMAN | [view interactions] | High throughput | no | no |
| TFP11_HUMAN | [view interactions] | High throughput | no | no |
| U2AF1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP42_HUMAN | [view interactions] | High throughput | no | no |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| RBM38_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CELF1_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDEL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTA2_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| CPEB4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| MEX3B_HUMAN | [view interactions] | High throughput | no | no |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |