4F2_HUMAN
Evidence for PS localization
Functions
(Microbial infection) In case of hepatitis C virus/HCV infection, the complex formed by SLC3A2 and SLC7A5/LAT1 plays a role in HCV propagation by facilitating viral entry into host cell and increasing L-leucine uptake-mediated mTORC1 signaling activation, thereby contributing to HCV-mediated pathogenesis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in 4F2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 43.5897 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 42.3077 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 42.3077 | 4 | no |
| GO:0019900 | kinase binding | 29.4872 | 4 | no |
| GO:0019901 | protein kinase binding | 28.2051 | 5 | no |
| GO:0016462 | pyrophosphatase activity | 26.9231 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 26.9231 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 26.9231 | 6 | no |
| GO:0003924 | GTPase activity | 24.3590 | 7 | no |
| GO:0005525 | GTP binding | 24.3590 | 5 | no |
| GO:0019001 | guanyl nucleotide binding | 24.3590 | 5 | no |
| GO:0032561 | guanyl ribonucleotide binding | 24.3590 | 5 | no |
| GO:0046872 | metal ion binding | 20.5128 | 4 | no |
| GO:0003723 | RNA binding | 15.3846 | 4 | yes |
| GO:0045296 | cadherin binding | 8.9744 | 4 | yes |
| GO:0008324 | cation transmembrane transporter activity | 5.1282 | 4 | yes |
| GO:0008509 | anion transmembrane transporter activity | 5.1282 | 4 | yes |
| GO:0022853 | active ion transmembrane transporter activity | 5.1282 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 5.1282 | 4 | yes |
| GO:0008514 | organic anion transmembrane transporter activity | 3.8462 | 5 | yes |
| GO:0046873 | metal ion transmembrane transporter activity | 3.8462 | 5 | yes |
| GO:0015081 | sodium ion transmembrane transporter activity | 2.5641 | 6 | yes |
| GO:0015085 | calcium ion transmembrane transporter activity | 2.5641 | 6 | yes |
| GO:0015291 | secondary active transmembrane transporter activity | 2.5641 | 4 | yes |
| GO:0015297 | antiporter activity | 2.5641 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in 4F2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 69.2308 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 60.2564 | 4 | no |
| GO:0010646 | regulation of cell communication | 56.4103 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 56.4103 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 53.8462 | 4 | no |
| GO:0009966 | regulation of signal transduction | 52.5641 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 50.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.7179 | 4 | no |
| GO:0006996 | organelle organization | 46.1538 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 46.1538 | 5 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.1538 | 4 | no |
| GO:0051049 | regulation of transport | 41.0256 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 41.0256 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 39.7436 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 39.7436 | 5 | no |
| GO:0022607 | cellular component assembly | 38.4615 | 4 | no |
| GO:0010468 | regulation of gene expression | 38.4615 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.4615 | 5 | no |
| GO:0008104 | protein localization | 34.6154 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 34.6154 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 34.6154 | 6 | no |
| GO:0010941 | regulation of cell death | 33.3333 | 4 | no |
| GO:0030030 | cell projection organization | 33.3333 | 4 | no |
| GO:0071310 | cellular response to organic substance | 33.3333 | 4 | no |
| GO:0023056 | positive regulation of signaling | 32.0513 | 4 | no |
| GO:0031399 | regulation of protein modification process | 32.0513 | 6 | no |
| GO:0033043 | regulation of organelle organization | 32.0513 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 30.7692 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 30.7692 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 30.7692 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.7692 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 30.7692 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.7692 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 29.4872 | 4 | no |
| GO:0071702 | organic substance transport | 29.4872 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 29.4872 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 29.4872 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 29.4872 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 29.4872 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 29.4872 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 29.4872 | 5 | no |
| GO:0030334 | regulation of cell migration | 29.4872 | 5 | no |
| GO:2000145 | regulation of cell motility | 29.4872 | 4 | no |
| GO:0071705 | nitrogen compound transport | 28.2051 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.2051 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 28.2051 | 5 | no |
| GO:0023057 | negative regulation of signaling | 28.2051 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 28.2051 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 28.2051 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 26.9231 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.9231 | 5 | no |
| GO:0036211 | protein modification process | 26.9231 | 4 | no |
| GO:0043412 | macromolecule modification | 26.9231 | 4 | no |
| GO:0032880 | regulation of protein localization | 26.9231 | 5 | no |
| GO:0060341 | regulation of cellular localization | 26.9231 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 26.9231 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 26.9231 | 6 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 26.9231 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.6410 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 25.6410 | 6 | no |
| GO:0031401 | positive regulation of protein modification process | 25.6410 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 25.6410 | 7 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 25.6410 | 7 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 25.6410 | 4 | no |
| GO:0007010 | cytoskeleton organization | 24.3590 | 5 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 24.3590 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 24.3590 | 5 | no |
| GO:0042327 | positive regulation of phosphorylation | 24.3590 | 8 | no |
| GO:0051050 | positive regulation of transport | 24.3590 | 4 | no |
| GO:0051336 | regulation of hydrolase activity | 24.3590 | 4 | no |
| GO:2000147 | positive regulation of cell motility | 23.0769 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 23.0769 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.0769 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.0769 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 23.0769 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.0769 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.0769 | 7 | no |
| GO:0051338 | regulation of transferase activity | 23.0769 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 23.0769 | 6 | no |
| GO:0031175 | neuron projection development | 23.0769 | 6 | no |
| GO:0051493 | regulation of cytoskeleton organization | 23.0769 | 6 | no |
| GO:0030155 | regulation of cell adhesion | 23.0769 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 23.0769 | 4 | no |
| GO:0008284 | positive regulation of cell population proliferation | 23.0769 | 5 | no |
| GO:0030335 | positive regulation of cell migration | 23.0769 | 6 | no |
| GO:0040017 | positive regulation of locomotion | 23.0769 | 4 | no |
| GO:0061024 | membrane organization | 21.7949 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 21.7949 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.7949 | 5 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 21.7949 | 8 | no |
| GO:0010628 | positive regulation of gene expression | 21.7949 | 6 | no |
| GO:0051241 | negative regulation of multicellular organismal process | 20.5128 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 20.5128 | 4 | no |
| GO:0009894 | regulation of catabolic process | 20.5128 | 4 | no |
| GO:0015031 | protein transport | 20.5128 | 4 | no |
| GO:0051347 | positive regulation of transferase activity | 20.5128 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 20.5128 | 4 | no |
| GO:1903829 | positive regulation of protein localization | 20.5128 | 5 | no |
| GO:0014070 | response to organic cyclic compound | 17.9487 | 4 | yes |
| GO:0006811 | ion transport | 11.5385 | 4 | yes |
| GO:0006812 | cation transport | 7.6923 | 5 | yes |
| GO:0006820 | anion transport | 5.1282 | 5 | yes |
| GO:0030001 | metal ion transport | 5.1282 | 6 | yes |
| GO:0098655 | cation transmembrane transport | 5.1282 | 4 | yes |
| GO:0006816 | calcium ion transport | 3.8462 | 7 | yes |
| GO:0015711 | organic anion transport | 3.8462 | 5 | yes |
| GO:0044000 | movement in host | 3.8462 | 4 | yes |
| GO:0098657 | import into cell | 3.8462 | 4 | yes |
| GO:0006865 | amino acid transport | 2.5641 | 5 | yes |
| GO:0015849 | organic acid transport | 2.5641 | 5 | yes |
| GO:0043330 | response to exogenous dsRNA | 2.5641 | 5 | yes |
| GO:0043331 | response to dsRNA | 2.5641 | 4 | yes |
| GO:0044409 | entry into host | 2.5641 | 5 | yes |
| GO:0046718 | viral entry into host cell | 2.5641 | 6 | yes |
| GO:0046942 | carboxylic acid transport | 2.5641 | 6 | yes |
| GO:0098656 | anion transmembrane transport | 2.5641 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in 4F2_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 2.5641 | 3 | no |
| DOID:0111962 | combined immunodeficiency | 2.5641 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 2.5641 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GPR37_HUMAN | [view interactions] | Low throughput | no | no |
| CD44_HUMAN | [view interactions] | Low throughput | no | yes |
| LAT1_HUMAN | [view interactions] | Low throughput | no | yes |
| NGAL_HUMAN | [view interactions] | Low throughput | no | no |
| TLC3A_HUMAN | [view interactions] | Low throughput | no | no |
| LAT2_HUMAN | [view interactions] | Low throughput | no | no |
| XCT_HUMAN | [view interactions] | Low throughput | no | no |
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CAH9_HUMAN | [view interactions] | Low throughput | no | no |
| YLAT1_HUMAN | [view interactions] | Low throughput | no | no |
| RT09_HUMAN | [view interactions] | High throughput | no | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACINU_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3I_HUMAN | [view interactions] | High throughput | no | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP1_HUMAN | [view interactions] | High throughput | no | no |
| SRSF3_HUMAN | [view interactions] | High throughput | no | yes |
| TRA2B_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| MGST1_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| TXNIP_HUMAN | [view interactions] | High throughput | no | no |
| IFT27_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| RHDF2_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| CD9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| TSN5_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| TSN15_HUMAN | [view interactions] | High throughput | no | yes |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK07_HUMAN | [view interactions] | High throughput | no | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CAV2_HUMAN | [view interactions] | High throughput | no | no |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP3_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ELOV5_HUMAN | [view interactions] | High throughput | no | yes |
| CNR2_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOAT1_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DHB11_HUMAN | [view interactions] | High throughput | no | yes |
| CD158_HUMAN | [view interactions] | High throughput | no | no |
| 3BHS7_HUMAN | [view interactions] | High throughput | no | no |
| RN169_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APBB1_HUMAN | [view interactions] | High throughput | no | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| ST32C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
| MET7A_HUMAN | [view interactions] | High throughput | no | no |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| T22D1_HUMAN | [view interactions] | High throughput | no | no |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEK6_HUMAN | [view interactions] | High throughput | no | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRF2_HUMAN | [view interactions] | High throughput | no | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| PHLA3_HUMAN | [view interactions] | High throughput | no | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP10_HUMAN | [view interactions] | High throughput | no | yes |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| CCR4_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| NPSR1_HUMAN | [view interactions] | High throughput | no | no |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S15A4_HUMAN | [view interactions] | High throughput | no | yes |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| TM216_HUMAN | [view interactions] | High throughput | no | no |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTDSL_HUMAN | [view interactions] | High throughput | no | no |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| PGFRB_HUMAN | [view interactions] | High throughput | no | yes |
| STYK1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EBP_HUMAN | [view interactions] | High throughput | no | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| ASB5_HUMAN | [view interactions] | High throughput | no | no |
| ASB11_HUMAN | [view interactions] | High throughput | no | no |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| LEG3_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| MBOA1_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| ITCH_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| ARMC8_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| PPAP_HUMAN | [view interactions] | High throughput | no | no |
| DUS12_HUMAN | [view interactions] | High throughput | no | no |
| DUS23_HUMAN | [view interactions] | High throughput | no | yes |
| DUS6_HUMAN | [view interactions] | High throughput | no | yes |
| DUS7_HUMAN | [view interactions] | High throughput | no | yes |
| DUS9_HUMAN | [view interactions] | High throughput | no | no |
| EYA2_HUMAN | [view interactions] | High throughput | no | yes |
| EYA3_HUMAN | [view interactions] | High throughput | no | no |
| MTMR7_HUMAN | [view interactions] | High throughput | no | no |
| PTPRO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STYL1_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| ELOB_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| RHG30_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| DNJC1_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| LRC61_HUMAN | [view interactions] | High throughput | no | yes |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| MARH2_HUMAN | [view interactions] | High throughput | no | yes |
| MARH3_HUMAN | [view interactions] | High throughput | no | no |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| IKBA_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEM6A_HUMAN | [view interactions] | High throughput | no | yes |
| TNFL9_HUMAN | [view interactions] | High throughput | no | no |
| ITA7_HUMAN | [view interactions] | High throughput | no | yes |
| ABHEA_HUMAN | [view interactions] | High throughput | no | yes |
| GALT7_HUMAN | [view interactions] | High throughput | no | no |
| DIK1A_HUMAN | [view interactions] | High throughput | no | yes |
| POMT1_HUMAN | [view interactions] | High throughput | no | no |
| MGT4B_HUMAN | [view interactions] | High throughput | no | no |
| MOT10_HUMAN | [view interactions] | High throughput | no | yes |
| PXL2A_HUMAN | [view interactions] | High throughput | no | yes |
| GET1_HUMAN | [view interactions] | High throughput | no | yes |
| LRFN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPD1L_HUMAN | [view interactions] | High throughput | no | no |
| LARG1_HUMAN | [view interactions] | High throughput | no | no |
| XPR1_HUMAN | [view interactions] | High throughput | no | yes |
| CGT_HUMAN | [view interactions] | High throughput | no | no |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| PIGB_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| LAT_HUMAN | [view interactions] | High throughput | no | no |
| CRBN_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFIP1_HUMAN | [view interactions] | High throughput | no | yes |
| PIGR_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YLAT2_HUMAN | [view interactions] | High throughput | no | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAMP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |