PSA4_HUMAN
Evidence for PS localization
Functions
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PSA4_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 30.4348 | 4 | no |
| GO:0003723 | RNA binding | 30.4348 | 4 | no |
| GO:0000166 | nucleotide binding | 28.2609 | 4 | no |
| GO:0017076 | purine nucleotide binding | 28.2609 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 27.1739 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.1739 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.9130 | 6 | no |
| GO:0005524 | ATP binding | 22.8261 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.8261 | 5 | no |
| GO:0016462 | pyrophosphatase activity | 21.7391 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 21.7391 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 21.7391 | 6 | no |
| GO:0043169 | cation binding | 20.6522 | 4 | no |
| GO:0046872 | metal ion binding | 20.6522 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PSA4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.8696 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 58.6957 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 58.6957 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 54.3478 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 45.6522 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.6522 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 44.5652 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 44.5652 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 43.4783 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 43.4783 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 42.3913 | 5 | no |
| GO:0010646 | regulation of cell communication | 41.3043 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.2174 | 5 | no |
| GO:0006996 | organelle organization | 36.9565 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 36.9565 | 5 | no |
| GO:0009966 | regulation of signal transduction | 34.7826 | 4 | no |
| GO:0010468 | regulation of gene expression | 34.7826 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.7826 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 31.5217 | 4 | no |
| GO:0009894 | regulation of catabolic process | 31.5217 | 4 | no |
| GO:0036211 | protein modification process | 31.5217 | 4 | no |
| GO:0043412 | macromolecule modification | 31.5217 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 30.4348 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 30.4348 | 5 | no |
| GO:0031399 | regulation of protein modification process | 30.4348 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.4348 | 4 | no |
| GO:0008104 | protein localization | 29.3478 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 29.3478 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 29.3478 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.3478 | 5 | no |
| GO:0023056 | positive regulation of signaling | 29.3478 | 4 | no |
| GO:0060341 | regulation of cellular localization | 29.3478 | 4 | no |
| GO:0022607 | cellular component assembly | 28.2609 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.2609 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 28.2609 | 5 | no |
| GO:0006508 | proteolysis | 27.1739 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 27.1739 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 27.1739 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.1739 | 5 | no |
| GO:0032880 | regulation of protein localization | 27.1739 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 26.0870 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 26.0870 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.0870 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 26.0870 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.0000 | 7 | no |
| GO:0010648 | negative regulation of cell communication | 25.0000 | 5 | no |
| GO:0023057 | negative regulation of signaling | 25.0000 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 25.0000 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0071310 | cellular response to organic substance | 25.0000 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.0000 | 6 | no |
| GO:0051049 | regulation of transport | 23.9130 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 22.8261 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.8261 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.8261 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.8261 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 22.8261 | 5 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.8261 | 6 | no |
| GO:0019941 | modification-dependent protein catabolic process | 21.7391 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 21.7391 | 5 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 21.7391 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 21.7391 | 7 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.7391 | 6 | no |
| GO:0030163 | protein catabolic process | 20.6522 | 4 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 20.6522 | 4 | yes |
| GO:0042176 | regulation of protein catabolic process | 20.6522 | 5 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 20.6522 | 8 | no |
| GO:0010638 | positive regulation of organelle organization | 20.6522 | 6 | no |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 19.5652 | 7 | yes |
| GO:0010498 | proteasomal protein catabolic process | 17.3913 | 5 | yes |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 17.3913 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PSA6_HUMAN | [view interactions] | Low throughput | no | yes |
| PSA5_HUMAN | [view interactions] | Low throughput | no | yes |
| PSA1_HUMAN | [view interactions] | Low throughput | no | yes |
| IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL1_HUMAN | [view interactions] | Low throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLK1_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PSB8_HUMAN | [view interactions] | Low throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | Low throughput | no | yes |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ASB10_HUMAN | [view interactions] | Low throughput | no | no |
| UBP14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PSMG3_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMG1_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMG4_HUMAN | [view interactions] | Low throughput | no | yes |
| AKIR2_HUMAN | [view interactions] | Low throughput | no | no |
| FOS_HUMAN | [view interactions] | Low throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PSA2_HUMAN | [view interactions] | Low throughput | no | yes |
| PSA3_HUMAN | [view interactions] | Low throughput | no | no |
| PSA7_HUMAN | [view interactions] | Low throughput | no | yes |
| POMP_HUMAN | [view interactions] | Low throughput | no | yes |
| PSMG2_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB5_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB4_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB1_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB3_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB2_HUMAN | [view interactions] | Low throughput | no | yes |
| PSB7_HUMAN | [view interactions] | Low throughput | no | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| BHE41_HUMAN | [view interactions] | Low throughput | no | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NSUN2_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| AIMP1_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GANAB_HUMAN | [view interactions] | High throughput | no | yes |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| GT251_HUMAN | [view interactions] | High throughput | no | no |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AMFR_HUMAN | [view interactions] | High throughput | no | yes |
| CNDP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF15_HUMAN | [view interactions] | High throughput | no | yes |
| PAAF1_HUMAN | [view interactions] | High throughput | no | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| RCC2_HUMAN | [view interactions] | High throughput | no | no |
| TLX2_HUMAN | [view interactions] | High throughput | no | no |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RYR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIG1_HUMAN | [view interactions] | High throughput | no | yes |
| MYPC3_HUMAN | [view interactions] | High throughput | no | no |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| IKZF1_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| TRI38_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| TFP11_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CI072_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| ADRM1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD4_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GATA1_HUMAN | [view interactions] | High throughput | no | no |
| REL_HUMAN | [view interactions] | High throughput | no | yes |
| CARD9_HUMAN | [view interactions] | High throughput | no | no |
| RN185_HUMAN | [view interactions] | High throughput | no | no |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RD23A_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEDD8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME2_HUMAN | [view interactions] | High throughput | no | no |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| HERC3_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| PTC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RELB_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| SHRPN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL4_HUMAN | [view interactions] | High throughput | no | yes |
| DESI1_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGFR2_HUMAN | [view interactions] | High throughput | no | no |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| VRK3_HUMAN | [view interactions] | High throughput | no | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN2_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| INSI2_HUMAN | [view interactions] | High throughput | no | yes |
| UNKL_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| MAF_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME4_HUMAN | [view interactions] | High throughput | no | yes |
| SELO_HUMAN | [view interactions] | High throughput | no | yes |
| PSMF1_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| CSTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COG2_HUMAN | [view interactions] | High throughput | no | no |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| SEML_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RITA1_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| MEN1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBX5_HUMAN | [view interactions] | High throughput | no | no |
| CDK7_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| DDI1_HUMAN | [view interactions] | High throughput | no | no |
| DDI2_HUMAN | [view interactions] | High throughput | no | no |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI3R4_HUMAN | [view interactions] | High throughput | no | yes |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| GOLI_HUMAN | [view interactions] | High throughput | no | yes |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| NQO1_HUMAN | [view interactions] | High throughput | no | no |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD5_HUMAN | [view interactions] | High throughput | no | yes |
| PSMA8_HUMAN | [view interactions] | High throughput | no | no |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YBOX1_HUMAN | [view interactions] | High throughput | no | yes |
| AP3M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPP38_HUMAN | [view interactions] | High throughput | no | yes |
| P5CR3_HUMAN | [view interactions] | High throughput | no | no |
| CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
| ELP6_HUMAN | [view interactions] | High throughput | no | no |
| EXOS4_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS5_HUMAN | [view interactions] | High throughput | no | yes |
| GET3_HUMAN | [view interactions] | High throughput | no | yes |
| CHMP5_HUMAN | [view interactions] | High throughput | no | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| ERO1B_HUMAN | [view interactions] | High throughput | no | yes |
| RT09_HUMAN | [view interactions] | High throughput | no | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAE2_HUMAN | [view interactions] | High throughput | no | yes |
| XPOT_HUMAN | [view interactions] | High throughput | no | no |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WDR11_HUMAN | [view interactions] | High throughput | no | yes |
| PSB10_HUMAN | [view interactions] | High throughput | no | no |
| PSMD9_HUMAN | [view interactions] | High throughput | no | yes |
| TXND5_HUMAN | [view interactions] | High throughput | no | yes |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| PSD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| G6PD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FPPS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR2_HUMAN | [view interactions] | High throughput | no | yes |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S10A2_HUMAN | [view interactions] | High throughput | no | no |
| PRDX3_HUMAN | [view interactions] | High throughput | no | yes |
| METK2_HUMAN | [view interactions] | High throughput | no | no |
| PROF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEM6_HUMAN | [view interactions] | High throughput | no | no |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| TXLNA_HUMAN | [view interactions] | High throughput | no | yes |
| SLX1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BABA1_HUMAN | [view interactions] | High throughput | no | yes |
| GARS_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| BUB1B_HUMAN | [view interactions] | High throughput | no | no |
| COPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB9_HUMAN | [view interactions] | High throughput | no | no |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| SYMC_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| SHLD3_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| GTF2I_HUMAN | [view interactions] | High throughput | no | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |