GSTM3_HUMAN
Evidence for PS localization
Functions
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GSTM3_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 37.7049 | 4 | no |
| GO:0043168 | anion binding | 36.0656 | 4 | yes |
| GO:0000166 | nucleotide binding | 34.4262 | 4 | no |
| GO:0017076 | purine nucleotide binding | 34.4262 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 29.5082 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 27.8689 | 6 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.8689 | 4 | no |
| GO:0045296 | cadherin binding | 24.5902 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.9508 | 5 | no |
| GO:0005524 | ATP binding | 21.3115 | 5 | no |
| GO:0016462 | pyrophosphatase activity | 21.3115 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 21.3115 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 21.3115 | 6 | no |
| GO:0031625 | ubiquitin protein ligase binding | 21.3115 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 21.3115 | 4 | no |
| GO:0042803 | protein homodimerization activity | 9.8361 | 4 | yes |
| GO:0004364 | glutathione transferase activity | 4.9180 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GSTM3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 57.3770 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 55.7377 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 55.7377 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 54.0984 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 54.0984 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 44.2623 | 4 | no |
| GO:0010468 | regulation of gene expression | 44.2623 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 44.2623 | 5 | no |
| GO:0010646 | regulation of cell communication | 44.2623 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 44.2623 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 44.2623 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 40.9836 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 40.9836 | 4 | no |
| GO:0009966 | regulation of signal transduction | 40.9836 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 40.9836 | 5 | no |
| GO:0006996 | organelle organization | 39.3443 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 39.3443 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 39.3443 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.7049 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 36.0656 | 5 | no |
| GO:0031399 | regulation of protein modification process | 34.4262 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 32.7869 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 32.7869 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 32.7869 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 32.7869 | 4 | no |
| GO:0022607 | cellular component assembly | 32.7869 | 4 | no |
| GO:0023056 | positive regulation of signaling | 31.1475 | 4 | no |
| GO:0043412 | macromolecule modification | 31.1475 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.1475 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 31.1475 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 29.5082 | 6 | no |
| GO:0010647 | positive regulation of cell communication | 29.5082 | 5 | no |
| GO:0036211 | protein modification process | 29.5082 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 27.8689 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 27.8689 | 6 | no |
| GO:0071310 | cellular response to organic substance | 27.8689 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 27.8689 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 27.8689 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 26.2295 | 4 | no |
| GO:0051049 | regulation of transport | 26.2295 | 4 | no |
| GO:0009894 | regulation of catabolic process | 26.2295 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.2295 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.2295 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.2295 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 26.2295 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 24.5902 | 5 | no |
| GO:0080134 | regulation of response to stress | 24.5902 | 4 | no |
| GO:0060341 | regulation of cellular localization | 24.5902 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 24.5902 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 24.5902 | 5 | no |
| GO:0008104 | protein localization | 24.5902 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 24.5902 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 24.5902 | 6 | no |
| GO:0009057 | macromolecule catabolic process | 24.5902 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.9508 | 5 | no |
| GO:0031400 | negative regulation of protein modification process | 22.9508 | 7 | no |
| GO:0032880 | regulation of protein localization | 22.9508 | 5 | no |
| GO:0043933 | protein-containing complex organization | 22.9508 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.9508 | 6 | no |
| GO:0045595 | regulation of cell differentiation | 21.3115 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 21.3115 | 4 | no |
| GO:0010629 | negative regulation of gene expression | 21.3115 | 7 | no |
| GO:1901565 | organonitrogen compound catabolic process | 21.3115 | 4 | no |
| GO:0001885 | endothelial cell development | 4.9180 | 5 | yes |
| GO:0002064 | epithelial cell development | 4.9180 | 4 | yes |
| GO:0018916 | nitrobenzene metabolic process | 4.9180 | 5 | yes |
| GO:0042178 | xenobiotic catabolic process | 4.9180 | 4 | yes |
| GO:0042537 | benzene-containing compound metabolic process | 4.9180 | 4 | yes |
| GO:0008065 | establishment of blood-nerve barrier | 3.2787 | 6 | yes |
| GO:0043627 | response to estrogen | 3.2787 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SPB5_HUMAN | [view interactions] | Low throughput | no | no |
| CAND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GSTM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZP4_HUMAN | [view interactions] | Low throughput | no | no |
| 3MG_HUMAN | [view interactions] | High throughput | no | yes |
| SOMA_HUMAN | [view interactions] | High throughput | no | no |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBL2_HUMAN | [view interactions] | High throughput | no | yes |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| GSTM1_HUMAN | [view interactions] | High throughput | no | yes |
| GSTM4_HUMAN | [view interactions] | High throughput | no | yes |
| CLVS2_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRLL_HUMAN | [view interactions] | High throughput | no | yes |
| KLH42_HUMAN | [view interactions] | High throughput | no | yes |
| F120B_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| KCD12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| DAAF5_HUMAN | [view interactions] | High throughput | no | no |
| VCIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| MK08_HUMAN | [view interactions] | High throughput | no | yes |
| DYR_HUMAN | [view interactions] | High throughput | no | yes |
| FOXK1_HUMAN | [view interactions] | High throughput | no | yes |
| NALP2_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ANKH1_HUMAN | [view interactions] | High throughput | no | yes |
| CTF18_HUMAN | [view interactions] | High throughput | no | no |
| TRIPC_HUMAN | [view interactions] | High throughput | no | yes |
| WNK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEMO_HUMAN | [view interactions] | High throughput | no | yes |
| NAB2_HUMAN | [view interactions] | High throughput | no | yes |
| TBD2B_HUMAN | [view interactions] | High throughput | no | yes |
| FOXK2_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QRIC1_HUMAN | [view interactions] | High throughput | no | yes |
| IKKB_HUMAN | [view interactions] | High throughput | no | yes |
| ABCF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYMPK_HUMAN | [view interactions] | High throughput | no | yes |
| PIGT_HUMAN | [view interactions] | High throughput | no | no |
| PDXD1_HUMAN | [view interactions] | High throughput | no | no |
| DCC1_HUMAN | [view interactions] | High throughput | no | yes |
| OXSR1_HUMAN | [view interactions] | High throughput | no | yes |
| BRAT1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSX2_HUMAN | [view interactions] | High throughput | no | no |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| CYTN_HUMAN | [view interactions] | High throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISCU_HUMAN | [view interactions] | High throughput | no | yes |
| DHX32_HUMAN | [view interactions] | High throughput | no | yes |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYEP_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G6PD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICAL_HUMAN | [view interactions] | High throughput | no | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S10A2_HUMAN | [view interactions] | High throughput | no | no |
| PRDX3_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYCC_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYRC_HUMAN | [view interactions] | High throughput | no | yes |
| HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIMP1_HUMAN | [view interactions] | High throughput | no | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CIAO3_HUMAN | [view interactions] | High throughput | no | yes |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| RBX2_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2C_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| DJB11_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| MCHR1_HUMAN | [view interactions] | High throughput | no | no |
| GSTM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTM5_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2L_HUMAN | [view interactions] | High throughput | no | no |
| SLBP_HUMAN | [view interactions] | High throughput | no | yes |
| PLSI_HUMAN | [view interactions] | High throughput | no | no |
| ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
| GNB1L_HUMAN | [view interactions] | High throughput | no | yes |
| LANC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPX2_HUMAN | [view interactions] | High throughput | no | yes |
| ANR16_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZP3_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| ATG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |