GSTM3_HUMAN
Evidence for PS localization
Functions
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GSTM3_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 21.8750 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 21.8750 | 5 | no |
| GO:0003723 | RNA binding | 21.8750 | 4 | no |
| GO:0045296 | cadherin binding | 21.8750 | 4 | no |
| GO:0004364 | glutathione transferase activity | 12.5000 | 4 | yes |
| GO:0042803 | protein homodimerization activity | 12.5000 | 4 | yes |
| GO:1900750 | oligopeptide binding | 9.3750 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GSTM3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 56.2500 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 56.2500 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 46.8750 | 4 | no |
| GO:0010646 | regulation of cell communication | 46.8750 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.8750 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 46.8750 | 4 | no |
| GO:0009966 | regulation of signal transduction | 43.7500 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 43.7500 | 4 | no |
| GO:0043412 | macromolecule modification | 37.5000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 37.5000 | 5 | no |
| GO:0010468 | regulation of gene expression | 34.3750 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 34.3750 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 34.3750 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 34.3750 | 5 | no |
| GO:0036211 | protein modification process | 31.2500 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 31.2500 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.2500 | 5 | no |
| GO:0010941 | regulation of cell death | 31.2500 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 31.2500 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 31.2500 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 28.1250 | 5 | no |
| GO:0051049 | regulation of transport | 28.1250 | 4 | no |
| GO:0071310 | cellular response to organic substance | 28.1250 | 4 | no |
| GO:0022607 | cellular component assembly | 28.1250 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 28.1250 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 25.0000 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.0000 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.0000 | 6 | no |
| GO:0009889 | regulation of biosynthetic process | 25.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.0000 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 25.0000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.0000 | 5 | no |
| GO:0019752 | carboxylic acid metabolic process | 25.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 25.0000 | 5 | no |
| GO:0043436 | oxoacid metabolic process | 25.0000 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.0000 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 25.0000 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.0000 | 6 | no |
| GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | no |
| GO:0006996 | organelle organization | 25.0000 | 4 | no |
| GO:0030162 | regulation of proteolysis | 25.0000 | 6 | no |
| GO:0031399 | regulation of protein modification process | 25.0000 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 25.0000 | 6 | no |
| GO:0060548 | negative regulation of cell death | 21.8750 | 5 | no |
| GO:0080134 | regulation of response to stress | 21.8750 | 4 | no |
| GO:0034762 | regulation of transmembrane transport | 21.8750 | 4 | no |
| GO:0034765 | regulation of ion transmembrane transport | 21.8750 | 5 | no |
| GO:0043269 | regulation of ion transport | 21.8750 | 5 | no |
| GO:0051050 | positive regulation of transport | 21.8750 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 21.8750 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.8750 | 6 | no |
| GO:0060341 | regulation of cellular localization | 21.8750 | 4 | no |
| GO:0006518 | peptide metabolic process | 21.8750 | 4 | yes |
| GO:0043603 | cellular amide metabolic process | 21.8750 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 21.8750 | 4 | no |
| GO:0031400 | negative regulation of protein modification process | 21.8750 | 7 | no |
| GO:0042981 | regulation of apoptotic process | 21.8750 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 21.8750 | 6 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.8750 | 5 | no |
| GO:0006749 | glutathione metabolic process | 18.7500 | 4 | yes |
| GO:0042178 | xenobiotic catabolic process | 12.5000 | 4 | yes |
| GO:0042537 | benzene-containing compound metabolic process | 12.5000 | 4 | yes |
| GO:0001885 | endothelial cell development | 9.3750 | 5 | yes |
| GO:0002064 | epithelial cell development | 9.3750 | 4 | yes |
| GO:0008065 | establishment of blood-nerve barrier | 6.2500 | 6 | yes |
| GO:0043627 | response to estrogen | 6.2500 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GSTM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZP4_HUMAN | [view interactions] | Low throughput | no | no |
| SPB5_HUMAN | [view interactions] | Low throughput | no | no |
| GSTM5_HUMAN | [view interactions] | High throughput | no | yes |
| TPX2_HUMAN | [view interactions] | High throughput | no | yes |
| LANC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNB1L_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
| PLSI_HUMAN | [view interactions] | High throughput | no | no |
| SLBP_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2L_HUMAN | [view interactions] | High throughput | no | no |
| ANR16_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZP3_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| ATG5_HUMAN | [view interactions] | High throughput | no | no |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| 3MG_HUMAN | [view interactions] | High throughput | no | yes |
| SOMA_HUMAN | [view interactions] | High throughput | no | no |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| RBL2_HUMAN | [view interactions] | High throughput | no | yes |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| GSTM1_HUMAN | [view interactions] | High throughput | no | yes |
| GSTM4_HUMAN | [view interactions] | High throughput | no | yes |
| CLVS2_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRLL_HUMAN | [view interactions] | High throughput | no | yes |
| KLH42_HUMAN | [view interactions] | High throughput | no | yes |
| F120B_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| KCD12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| DAAF5_HUMAN | [view interactions] | High throughput | no | no |
| VCIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| MK08_HUMAN | [view interactions] | High throughput | no | yes |
| DYR_HUMAN | [view interactions] | High throughput | no | yes |
| FOXK1_HUMAN | [view interactions] | High throughput | no | yes |
| NALP2_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ANKH1_HUMAN | [view interactions] | High throughput | no | yes |
| CTF18_HUMAN | [view interactions] | High throughput | no | no |
| TRIPC_HUMAN | [view interactions] | High throughput | no | yes |
| WNK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEMO_HUMAN | [view interactions] | High throughput | no | yes |
| NAB2_HUMAN | [view interactions] | High throughput | no | yes |
| TBD2B_HUMAN | [view interactions] | High throughput | no | yes |
| FOXK2_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QRIC1_HUMAN | [view interactions] | High throughput | no | yes |
| IKKB_HUMAN | [view interactions] | High throughput | no | yes |
| ABCF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYMPK_HUMAN | [view interactions] | High throughput | no | yes |
| PIGT_HUMAN | [view interactions] | High throughput | no | no |
| PDXD1_HUMAN | [view interactions] | High throughput | no | no |
| DCC1_HUMAN | [view interactions] | High throughput | no | yes |
| OXSR1_HUMAN | [view interactions] | High throughput | no | yes |
| BRAT1_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISCU_HUMAN | [view interactions] | High throughput | no | yes |
| DHX32_HUMAN | [view interactions] | High throughput | no | yes |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| DJB11_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| GSTM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GSHR_HUMAN | [view interactions] | Computational | no | yes |
| GPX5_HUMAN | [view interactions] | Computational | no | no |
| GSTO2_HUMAN | [view interactions] | Computational | no | no |
| GSTO1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GPX8_HUMAN | [view interactions] | Computational | no | no |
| HYEP_HUMAN | [view interactions] | Computational | no | no |
| GSTT2_HUMAN | [view interactions] | Computational | no | no |