ABCF3_HUMAN
Evidence for PS localization
Functions
Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABCF3_HUMAN |
|---|---|---|---|---|
| GO:0045296 | cadherin binding | 32.0000 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 20.0000 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 20.0000 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 20.0000 | 4 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 20.0000 | 5 | yes |
| GO:0005524 | ATP binding | 16.0000 | 5 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 16.0000 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABCF3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 52.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 52.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 44.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 44.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 44.0000 | 4 | no |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 40.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.0000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 36.0000 | 5 | no |
| GO:0008104 | protein localization | 36.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.0000 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.0000 | 5 | no |
| GO:0071310 | cellular response to organic substance | 32.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 32.0000 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 28.0000 | 4 | no |
| GO:0033043 | regulation of organelle organization | 28.0000 | 5 | no |
| GO:0051049 | regulation of transport | 28.0000 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.0000 | 5 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 28.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 28.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.0000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 28.0000 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 28.0000 | 5 | no |
| GO:0007010 | cytoskeleton organization | 24.0000 | 5 | no |
| GO:0031399 | regulation of protein modification process | 24.0000 | 6 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 24.0000 | 5 | no |
| GO:0071417 | cellular response to organonitrogen compound | 24.0000 | 4 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 24.0000 | 4 | no |
| GO:1901699 | cellular response to nitrogen compound | 24.0000 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.0000 | 6 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 24.0000 | 6 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 24.0000 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 24.0000 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 24.0000 | 6 | no |
| GO:0009894 | regulation of catabolic process | 24.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 24.0000 | 4 | no |
| GO:0030030 | cell projection organization | 24.0000 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 24.0000 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.0000 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 24.0000 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 24.0000 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 24.0000 | 6 | no |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ABCF3_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 12.0000 | 3 | no |
| DOID:0111198 | autosomal dominant distal hereditary motor neuronopathy | 8.0000 | 7 | no |
| DOID:12377 | spinal muscular atrophy | 8.0000 | 6 | no |
| DOID:1289 | neurodegenerative disease | 8.0000 | 4 | no |
| DOID:231 | motor neuron disease | 8.0000 | 5 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| FCSD2_HUMAN | [view interactions] | High throughput | no | no |
| ACINU_HUMAN | [view interactions] | High throughput | no | yes |
| IDLC_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOE1_HUMAN | [view interactions] | High throughput | no | yes |
| LEU1_HUMAN | [view interactions] | High throughput | no | no |
| NOA1_HUMAN | [view interactions] | High throughput | no | yes |
| HIRP3_HUMAN | [view interactions] | High throughput | no | no |
| MOC2B_HUMAN | [view interactions] | High throughput | no | yes |
| S35E1_HUMAN | [view interactions] | High throughput | no | yes |
| OSTP_HUMAN | [view interactions] | High throughput | no | yes |
| TBPL1_HUMAN | [view interactions] | High throughput | no | yes |
| FOXL1_HUMAN | [view interactions] | High throughput | no | no |
| TEAD2_HUMAN | [view interactions] | High throughput | no | no |
| RAB38_HUMAN | [view interactions] | High throughput | no | no |
| CCD33_HUMAN | [view interactions] | High throughput | no | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| MDFI_HUMAN | [view interactions] | High throughput | no | no |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| RBPMS_HUMAN | [view interactions] | High throughput | no | no |
| THAP1_HUMAN | [view interactions] | High throughput | no | no |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| RIOK2_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYTC2_HUMAN | [view interactions] | High throughput | no | yes |
| TPP2_HUMAN | [view interactions] | High throughput | no | yes |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LGI1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPTB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTMR4_HUMAN | [view interactions] | High throughput | no | no |
| HNRC2_HUMAN | [view interactions] | High throughput | no | no |
| M1IP1_HUMAN | [view interactions] | High throughput | no | yes |
| FYCO1_HUMAN | [view interactions] | High throughput | no | no |
| NEST_HUMAN | [view interactions] | High throughput | no | no |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| RPKL1_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR3_HUMAN | [view interactions] | High throughput | no | no |
| TCPQM_HUMAN | [view interactions] | High throughput | no | no |
| DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| ZB10P_HUMAN | [view interactions] | High throughput | no | yes |
| PKHG7_HUMAN | [view interactions] | High throughput | no | no |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| PI5L1_HUMAN | [view interactions] | High throughput | no | no |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIB2_HUMAN | [view interactions] | High throughput | no | yes |
| YPEL3_HUMAN | [view interactions] | High throughput | no | yes |
| PDE4D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLBL1_HUMAN | [view interactions] | High throughput | no | no |
| ASB6_HUMAN | [view interactions] | High throughput | no | yes |
| KLK15_HUMAN | [view interactions] | High throughput | no | no |
| ESPB1_HUMAN | [view interactions] | High throughput | no | no |
| TRI35_HUMAN | [view interactions] | High throughput | no | yes |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| ZNRD2_HUMAN | [view interactions] | High throughput | no | yes |
| PPARD_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT3_HUMAN | [view interactions] | High throughput | no | yes |
| D2HDH_HUMAN | [view interactions] | High throughput | no | no |
| KCD14_HUMAN | [view interactions] | High throughput | no | no |
| TLC3A_HUMAN | [view interactions] | High throughput | no | no |
| ARL4D_HUMAN | [view interactions] | High throughput | no | no |
| GSTM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNAI2_HUMAN | [view interactions] | High throughput | no | no |
| RFXK_HUMAN | [view interactions] | High throughput | no | yes |
| CLASR_HUMAN | [view interactions] | High throughput | no | yes |
| DYR_HUMAN | [view interactions] | High throughput | no | yes |
| UBP32_HUMAN | [view interactions] | High throughput | no | yes |
| PSG11_HUMAN | [view interactions] | High throughput | no | no |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| BTLA_HUMAN | [view interactions] | High throughput | no | no |
| HSPB8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPAS1_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| ABCF2_HUMAN | [view interactions] | High throughput | no | yes |
| INT2_HUMAN | [view interactions] | High throughput | no | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLRP9_HUMAN | [view interactions] | High throughput | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| GCN1_HUMAN | [view interactions] | Computational | no | yes |
| EF1G_HUMAN | [view entry] [view interactions] | Computational | yes | yes |