ABCF3_HUMAN
Evidence for PS localization
Functions
Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B. [View more on UniProt]
Protein features
Transmembrane
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 46%
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Close ✖
ABCF3_HUMAN has binary interactions with 27 proteins
Isoforms
Interacting regions
Canonical [ABCF3_HUMAN]
Isoform [F8WCU6] alignment
Isoform [Q9NUQ8-2] alignment
LOADING 72%
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABCF3_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 32.1429 | 4 | yes |
| GO:0045296 | cadherin binding | 28.5714 | 4 | yes |
| GO:0000166 | nucleotide binding | 25.0000 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 25.0000 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 25.0000 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 21.4286 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 21.4286 | 5 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.4286 | 4 | yes |
| GO:0003723 | RNA binding | 21.4286 | 4 | no |
| GO:0005524 | ATP binding | 17.8571 | 5 | yes |
| GO:0016462 | pyrophosphatase activity | 17.8571 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 17.8571 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 17.8571 | 6 | yes |
| GO:0016887 | ATP hydrolysis activity | 14.2857 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABCF3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 67.8571 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 60.7143 | 4 | no |
| GO:0010646 | regulation of cell communication | 50.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 46.4286 | 4 | no |
| GO:0008104 | protein localization | 46.4286 | 4 | no |
| GO:0006996 | organelle organization | 42.8571 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.8571 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 35.7143 | 4 | no |
| GO:0010468 | regulation of gene expression | 35.7143 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.7143 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 35.7143 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 35.7143 | 5 | no |
| GO:0051049 | regulation of transport | 35.7143 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 35.7143 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.1429 | 5 | no |
| GO:0071310 | cellular response to organic substance | 32.1429 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 32.1429 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.1429 | 5 | no |
| GO:0033043 | regulation of organelle organization | 32.1429 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 32.1429 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.1429 | 5 | no |
| GO:0009966 | regulation of signal transduction | 28.5714 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.5714 | 5 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABCF2_HUMAN | [view interactions] | High throughput | no | yes |
| ACINU_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARL4D_HUMAN | [view interactions] | High throughput | no | no |
| ASB6_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTLA_HUMAN | [view interactions] | High throughput | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCD33_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| CDN1B_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| CIB2_HUMAN | [view interactions] | High throughput | no | yes |
| CLASR_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT3_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTN_HUMAN | [view interactions] | High throughput | no | no |
| D2HDH_HUMAN | [view interactions] | High throughput | no | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |