HSP76_HUMAN
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed). [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in HSP76_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 46.4789 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 42.2535 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 42.2535 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 40.8451 | 5 | yes |
GO:0005524 | ATP binding | 36.6197 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 36.6197 | 5 | yes |
GO:0019900 | kinase binding | 29.5775 | 4 | no |
GO:0019901 | protein kinase binding | 28.1690 | 5 | no |
GO:0031625 | ubiquitin protein ligase binding | 23.9437 | 5 | yes |
GO:0044389 | ubiquitin-like protein ligase binding | 23.9437 | 4 | yes |
GO:0016462 | pyrophosphatase activity | 19.7183 | 5 | yes |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 19.7183 | 4 | yes |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 19.7183 | 6 | yes |
GO:0016887 | ATP hydrolysis activity | 12.6761 | 7 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in HSP76_HUMAN |
---|---|---|---|---|
GO:0060255 | regulation of macromolecule metabolic process | 64.7887 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 61.9718 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 60.5634 | 4 | no |
GO:0048522 | positive regulation of cellular process | 59.1549 | 4 | no |
GO:0048523 | negative regulation of cellular process | 57.7465 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 56.3380 | 4 | no |
GO:0010646 | regulation of cell communication | 49.2958 | 4 | no |
GO:0009966 | regulation of signal transduction | 47.8873 | 4 | no |
GO:0051128 | regulation of cellular component organization | 46.4789 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 46.4789 | 5 | no |
GO:0009889 | regulation of biosynthetic process | 45.0704 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 45.0704 | 5 | no |
GO:0010468 | regulation of gene expression | 43.6620 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 42.2535 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 42.2535 | 4 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 42.2535 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 42.2535 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 42.2535 | 5 | no |
GO:0006996 | organelle organization | 40.8451 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 39.4366 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 39.4366 | 5 | no |
GO:0010941 | regulation of cell death | 39.4366 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 39.4366 | 5 | no |
GO:0006355 | regulation of DNA-templated transcription | 38.0282 | 6 | no |
GO:0042981 | regulation of apoptotic process | 38.0282 | 6 | no |
GO:0043067 | regulation of programmed cell death | 38.0282 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 38.0282 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 38.0282 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 38.0282 | 6 | no |
GO:0031325 | positive regulation of cellular metabolic process | 36.6197 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 35.2113 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 35.2113 | 5 | no |
GO:0008104 | protein localization | 33.8028 | 4 | no |
GO:0031399 | regulation of protein modification process | 33.8028 | 6 | no |
GO:0048585 | negative regulation of response to stimulus | 33.8028 | 4 | no |
GO:0010647 | positive regulation of cell communication | 32.3944 | 5 | no |
GO:0023056 | positive regulation of signaling | 32.3944 | 4 | no |
GO:0051049 | regulation of transport | 32.3944 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 32.3944 | 6 | no |
GO:0009967 | positive regulation of signal transduction | 30.9859 | 5 | no |
GO:0009968 | negative regulation of signal transduction | 30.9859 | 5 | no |
GO:0010648 | negative regulation of cell communication | 30.9859 | 5 | no |
GO:0023057 | negative regulation of signaling | 30.9859 | 4 | no |
GO:0036211 | protein modification process | 30.9859 | 4 | no |
GO:0043066 | negative regulation of apoptotic process | 30.9859 | 7 | no |
GO:0043069 | negative regulation of programmed cell death | 30.9859 | 6 | no |
GO:0043412 | macromolecule modification | 30.9859 | 4 | no |
GO:0060548 | negative regulation of cell death | 30.9859 | 5 | no |
GO:0071310 | cellular response to organic substance | 29.5775 | 4 | yes |
GO:0015031 | protein transport | 28.1690 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 28.1690 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 28.1690 | 6 | no |
GO:0071702 | organic substance transport | 28.1690 | 4 | no |
GO:0071705 | nitrogen compound transport | 28.1690 | 4 | no |
GO:0080134 | regulation of response to stress | 28.1690 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 28.1690 | 4 | no |
GO:0042127 | regulation of cell population proliferation | 28.1690 | 4 | no |
GO:0016192 | vesicle-mediated transport | 26.7606 | 4 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 26.7606 | 6 | no |
GO:0009894 | regulation of catabolic process | 26.7606 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 26.7606 | 4 | no |
GO:0060341 | regulation of cellular localization | 25.3521 | 4 | no |
GO:0051338 | regulation of transferase activity | 25.3521 | 4 | no |
GO:0010243 | response to organonitrogen compound | 23.9437 | 4 | no |
GO:0022607 | cellular component assembly | 23.9437 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 23.9437 | 6 | no |
GO:0030162 | regulation of proteolysis | 23.9437 | 6 | no |
GO:0033043 | regulation of organelle organization | 23.9437 | 5 | no |
GO:0042325 | regulation of phosphorylation | 23.9437 | 7 | no |
GO:0051174 | regulation of phosphorus metabolic process | 23.9437 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 23.9437 | 4 | no |
GO:0051129 | negative regulation of cellular component organization | 22.5352 | 5 | no |
GO:0032880 | regulation of protein localization | 22.5352 | 5 | no |
GO:0001932 | regulation of protein phosphorylation | 21.1268 | 7 | no |
GO:0031401 | positive regulation of protein modification process | 21.1268 | 7 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.1268 | 6 | no |
GO:0050776 | regulation of immune response | 21.1268 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 21.1268 | 5 | no |
GO:1902532 | negative regulation of intracellular signal transduction | 21.1268 | 6 | no |
GO:0006886 | intracellular protein transport | 21.1268 | 4 | no |
GO:0007010 | cytoskeleton organization | 21.1268 | 5 | no |
GO:0006986 | response to unfolded protein | 19.7183 | 4 | yes |
GO:0051084 | de novo post-translational protein folding | 12.6761 | 4 | yes |
GO:0051085 | chaperone cofactor-dependent protein refolding | 12.6761 | 4 | yes |
GO:0035967 | cellular response to topologically incorrect protein | 11.2676 | 4 | yes |
GO:0034620 | cellular response to unfolded protein | 9.8592 | 5 | yes |
GO:0034605 | cellular response to heat | 8.4507 | 4 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in HSP76_HUMAN |
---|---|---|---|---|
DOID:114 | heart disease | 4.2254 | 3 | no |
DOID:65 | connective tissue disease | 2.8169 | 3 | no |
DOID:0050700 | cardiomyopathy | 2.8169 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 2.8169 | 5 | no |
DOID:12930 | dilated cardiomyopathy | 2.8169 | 6 | no |
DOID:0050686 | organ system cancer | 2.8169 | 3 | no |
DOID:6457 | Cowden syndrome | 2.8169 | 3 | no |
DOID:0080001 | bone disease | 2.8169 | 4 | no |
DOID:0080006 | bone development disease | 2.8169 | 5 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
FUND1_HUMAN | [view interactions] | Low throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SKAP_HUMAN | [view interactions] | Low throughput | no | yes |
RO52_HUMAN | [view interactions] | Low throughput | no | yes |
FAF1_HUMAN | [view interactions] | High throughput | no | yes |
TET2_HUMAN | [view interactions] | High throughput | no | yes |
PPARG_HUMAN | [view interactions] | High throughput | no | yes |
ZFY21_HUMAN | [view interactions] | High throughput | no | yes |
ATX3_HUMAN | [view interactions] | High throughput | no | yes |
VRK3_HUMAN | [view interactions] | High throughput | no | yes |
H4_HUMAN | [view interactions] | High throughput | no | yes |
PTMA_HUMAN | [view interactions] | High throughput | no | yes |
ARAF_HUMAN | [view interactions] | High throughput | no | yes |
CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
LMBRL_HUMAN | [view interactions] | High throughput | no | no |
NFX1_HUMAN | [view interactions] | High throughput | no | yes |
PINK1_HUMAN | [view interactions] | High throughput | no | yes |
YAP1_HUMAN | [view interactions] | High throughput | no | yes |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBS3A_HUMAN | [view interactions] | High throughput | no | no |
BRD4_HUMAN | [view interactions] | High throughput | no | yes |
RN185_HUMAN | [view interactions] | High throughput | no | no |
DJB11_HUMAN | [view interactions] | High throughput | no | yes |
DNJB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJB3_HUMAN | [view interactions] | High throughput | no | no |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG1_HUMAN | [view interactions] | High throughput | no | yes |
SPT6H_HUMAN | [view interactions] | High throughput | no | yes |
BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PSB2_HUMAN | [view interactions] | High throughput | no | yes |
FZR1_HUMAN | [view interactions] | High throughput | no | no |
TEDC1_HUMAN | [view interactions] | High throughput | no | no |
CBPC6_HUMAN | [view interactions] | High throughput | no | yes |
PLPL5_HUMAN | [view interactions] | High throughput | no | no |
FA12_HUMAN | [view interactions] | High throughput | no | no |
GALA_HUMAN | [view interactions] | High throughput | no | no |
NDRG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LST8_HUMAN | [view interactions] | High throughput | no | yes |
OD3L1_HUMAN | [view interactions] | High throughput | no | no |
LIME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFFL_HUMAN | [view interactions] | High throughput | no | yes |
TRABD_HUMAN | [view interactions] | High throughput | no | yes |
NR1I3_HUMAN | [view interactions] | High throughput | no | no |
CDK20_HUMAN | [view interactions] | High throughput | no | yes |
MYO1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFPL2_HUMAN | [view interactions] | High throughput | no | no |
GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CC117_HUMAN | [view interactions] | High throughput | no | yes |
CC038_HUMAN | [view interactions] | High throughput | no | yes |
LRC8E_HUMAN | [view interactions] | High throughput | no | no |
CPLN2_HUMAN | [view interactions] | High throughput | no | yes |
PELI3_HUMAN | [view interactions] | High throughput | no | yes |
ZN488_HUMAN | [view interactions] | High throughput | no | no |
FA83F_HUMAN | [view interactions] | High throughput | no | no |
DHR13_HUMAN | [view interactions] | High throughput | no | yes |
PAXI1_HUMAN | [view interactions] | High throughput | no | no |
SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBX38_HUMAN | [view interactions] | High throughput | no | yes |
CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
T106B_HUMAN | [view interactions] | High throughput | no | yes |
PML_HUMAN | [view interactions] | High throughput | no | yes |
DNJB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
GBRAP_HUMAN | [view interactions] | High throughput | no | no |
IQCB1_HUMAN | [view interactions] | High throughput | no | no |
MLF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RIPK4_HUMAN | [view interactions] | High throughput | no | no |
OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
SIDT2_HUMAN | [view interactions] | High throughput | no | yes |
SGTB_HUMAN | [view interactions] | High throughput | no | yes |
HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IFT27_HUMAN | [view interactions] | High throughput | no | yes |
TT30B_HUMAN | [view interactions] | High throughput | no | no |
POC1A_HUMAN | [view interactions] | High throughput | no | yes |
HPBP1_HUMAN | [view interactions] | High throughput | no | yes |
KLH34_HUMAN | [view interactions] | High throughput | no | no |
ILK_HUMAN | [view interactions] | High throughput | no | no |
ABH15_HUMAN | [view interactions] | High throughput | no | yes |
MOCS3_HUMAN | [view interactions] | High throughput | no | yes |
NTNG1_HUMAN | [view interactions] | High throughput | no | no |
NEK4_HUMAN | [view interactions] | High throughput | no | yes |
PRD16_HUMAN | [view interactions] | High throughput | no | no |
AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTK6_HUMAN | [view interactions] | High throughput | no | yes |
SOCS1_HUMAN | [view interactions] | High throughput | no | yes |
MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MP2K5_HUMAN | [view interactions] | High throughput | no | yes |
PDPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK_HUMAN | [view interactions] | High throughput | no | yes |
PAXI_HUMAN | [view interactions] | High throughput | no | yes |
PTN12_HUMAN | [view interactions] | High throughput | no | yes |
MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K14_HUMAN | [view interactions] | High throughput | no | yes |
DUS6_HUMAN | [view interactions] | High throughput | no | yes |
BAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ELK1_HUMAN | [view interactions] | High throughput | no | yes |
PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KPCG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KS6A1_HUMAN | [view interactions] | High throughput | no | yes |
HDAC1_HUMAN | [view interactions] | High throughput | no | no |
UFO_HUMAN | [view interactions] | High throughput | no | no |
GAB2_HUMAN | [view interactions] | High throughput | no | yes |
KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BRAF_HUMAN | [view interactions] | High throughput | no | yes |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MOT11_HUMAN | [view interactions] | High throughput | no | no |
PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STYX_HUMAN | [view interactions] | High throughput | no | yes |
SNIP1_HUMAN | [view interactions] | High throughput | no | no |
E2F3_HUMAN | [view interactions] | High throughput | no | no |
TERF1_HUMAN | [view interactions] | High throughput | no | no |
TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BCL3_HUMAN | [view interactions] | High throughput | no | yes |
OASL_HUMAN | [view interactions] | High throughput | no | no |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
JUN_HUMAN | [view interactions] | High throughput | no | yes |
TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BMI1_HUMAN | [view interactions] | High throughput | no | yes |
CISH_HUMAN | [view interactions] | High throughput | no | yes |
CP4FC_HUMAN | [view interactions] | High throughput | no | no |
ADCK5_HUMAN | [view interactions] | High throughput | no | yes |
BAG4_HUMAN | [view interactions] | High throughput | no | yes |
COMD6_HUMAN | [view interactions] | High throughput | no | no |
LEG7_HUMAN | [view interactions] | High throughput | no | no |
KT222_HUMAN | [view interactions] | High throughput | no | no |
SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRAP1_HUMAN | [view interactions] | High throughput | no | no |
REL_HUMAN | [view interactions] | High throughput | no | yes |
NEMO_HUMAN | [view interactions] | High throughput | no | yes |
M3K1_HUMAN | [view interactions] | High throughput | no | yes |
M3K3_HUMAN | [view interactions] | High throughput | no | no |
RELB_HUMAN | [view interactions] | High throughput | no | yes |
RIPK2_HUMAN | [view interactions] | High throughput | no | yes |
TAB1_HUMAN | [view interactions] | High throughput | no | yes |
TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
TNR1B_HUMAN | [view interactions] | High throughput | no | no |
CSN5_HUMAN | [view interactions] | High throughput | no | yes |
CUL1_HUMAN | [view interactions] | High throughput | no | yes |
NEDD8_HUMAN | [view interactions] | High throughput | no | yes |
SMAD6_HUMAN | [view interactions] | High throughput | no | no |
STK4_HUMAN | [view interactions] | High throughput | no | yes |
NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
JMY_HUMAN | [view interactions] | High throughput | no | yes |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
NEK8_HUMAN | [view interactions] | High throughput | no | yes |
NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
NECD_HUMAN | [view interactions] | High throughput | no | no |
CV015_HUMAN | [view interactions] | High throughput | no | no |
FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CDK9_HUMAN | [view interactions] | High throughput | no | yes |
RPAP3_HUMAN | [view interactions] | High throughput | no | yes |
MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
COP1_HUMAN | [view interactions] | High throughput | no | no |
DYRK2_HUMAN | [view interactions] | High throughput | no | yes |
INSI2_HUMAN | [view interactions] | High throughput | no | yes |
PARD3_HUMAN | [view interactions] | High throughput | no | yes |
SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
CBL_HUMAN | [view interactions] | High throughput | no | yes |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NOS2_HUMAN | [view interactions] | High throughput | no | yes |
UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
P53_HUMAN | [view interactions] | High throughput | no | no |
DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA4_HUMAN | [view interactions] | High throughput | no | yes |
DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJB5_HUMAN | [view interactions] | High throughput | no | yes |
DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJB7_HUMAN | [view interactions] | High throughput | no | no |
DNJB8_HUMAN | [view interactions] | High throughput | no | no |
CCNI2_HUMAN | [view interactions] | High throughput | no | no |
LRC28_HUMAN | [view interactions] | High throughput | no | yes |
VASH1_HUMAN | [view interactions] | High throughput | no | yes |
P33MX_HUMAN | [view interactions] | High throughput | no | yes |
NXF5_HUMAN | [view interactions] | High throughput | no | no |
TSSK1_HUMAN | [view interactions] | High throughput | no | no |
KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GAN_HUMAN | [view interactions] | High throughput | no | yes |
SKI_HUMAN | [view interactions] | High throughput | no | yes |
MCM2_HUMAN | [view interactions] | High throughput | no | no |
MCM5_HUMAN | [view interactions] | High throughput | no | no |
KSR1_HUMAN | [view interactions] | High throughput | no | yes |
RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
PROD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VILL_HUMAN | [view interactions] | High throughput | no | no |
CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGLN3_HUMAN | [view interactions] | High throughput | no | no |
LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
PRP8_HUMAN | [view interactions] | High throughput | no | yes |
AAR2_HUMAN | [view interactions] | High throughput | no | no |
PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
LARP7_HUMAN | [view interactions] | High throughput | no | yes |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
TLR9_HUMAN | [view interactions] | High throughput | no | no |
IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P121C_HUMAN | [view interactions] | Computational | no | yes |
NU153_HUMAN | [view interactions] | Computational | no | yes |
NUP37_HUMAN | [view interactions] | Computational | no | yes |
F10A1_HUMAN | [view interactions] | Computational | no | yes |
P121A_HUMAN | [view interactions] | Computational | no | yes |
NU133_HUMAN | [view interactions] | Computational | no | yes |
NUP35_HUMAN | [view interactions] | Computational | no | yes |
NUP85_HUMAN | [view interactions] | Computational | no | yes |
NUP93_HUMAN | [view interactions] | Computational | no | yes |
NU107_HUMAN | [view interactions] | Computational | no | no |
HS105_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAE1L_HUMAN | [view interactions] | Computational | no | no |
NUP62_HUMAN | [view interactions] | Computational | no | yes |
NUP54_HUMAN | [view interactions] | Computational | no | yes |
NUP43_HUMAN | [view interactions] | Computational | no | yes |
PO210_HUMAN | [view interactions] | Computational | no | yes |
NU160_HUMAN | [view interactions] | Computational | no | no |
NUP98_HUMAN | [view interactions] | Computational | no | no |
TLR2_HUMAN | [view interactions] | Computational | no | no |
RBP2_HUMAN | [view interactions] | Computational | no | yes |
NUP58_HUMAN | [view interactions] | Computational | no | yes |
TPR_HUMAN | [view interactions] | Computational | no | yes |
AAAS_HUMAN | [view interactions] | Computational | no | yes |
NU188_HUMAN | [view interactions] | Computational | no | yes |
NDC1_HUMAN | [view interactions] | Computational | no | yes |
BAG2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
DNJC2_HUMAN | [view interactions] | Computational | no | yes |
NUP50_HUMAN | [view interactions] | Computational | no | yes |
SEH1_HUMAN | [view interactions] | Computational | no | no |
NUP42_HUMAN | [view interactions] | Computational | no | no |
SEC13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NU214_HUMAN | [view interactions] | Computational | no | no |
NUP88_HUMAN | [view interactions] | Computational | no | yes |
NU205_HUMAN | [view interactions] | Computational | no | no |
NU155_HUMAN | [view interactions] | Computational | no | yes |