CSN3_HUMAN
Evidence for PS localization
Functions
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CSN3_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 31.9444 | 4 | no |
| GO:0000166 | nucleotide binding | 30.5556 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.5556 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 30.5556 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.1667 | 4 | no |
| GO:0031625 | ubiquitin protein ligase binding | 25.0000 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 25.0000 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.6111 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 23.6111 | 5 | no |
| GO:0003723 | RNA binding | 23.6111 | 4 | no |
| GO:0005524 | ATP binding | 22.2222 | 5 | no |
| GO:0043169 | cation binding | 20.8333 | 4 | no |
| GO:0046872 | metal ion binding | 20.8333 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CSN3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.1667 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 48.6111 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.8333 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 45.8333 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.6667 | 4 | yes |
| GO:0006996 | organelle organization | 38.8889 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 37.5000 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 36.1111 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.1111 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 36.1111 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.3333 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.9444 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 31.9444 | 5 | no |
| GO:0043412 | macromolecule modification | 30.5556 | 4 | yes |
| GO:0010468 | regulation of gene expression | 30.5556 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.5556 | 4 | no |
| GO:0031399 | regulation of protein modification process | 29.1667 | 6 | yes |
| GO:0036211 | protein modification process | 29.1667 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 29.1667 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 29.1667 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 29.1667 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.1667 | 5 | no |
| GO:0022607 | cellular component assembly | 29.1667 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 27.7778 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 26.3889 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 25.0000 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 25.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.0000 | 4 | no |
| GO:0023057 | negative regulation of signaling | 25.0000 | 4 | no |
| GO:0007010 | cytoskeleton organization | 25.0000 | 5 | no |
| GO:0008104 | protein localization | 25.0000 | 4 | no |
| GO:0009057 | macromolecule catabolic process | 23.6111 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 23.6111 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.6111 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.6111 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.6111 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 23.6111 | 4 | no |
| GO:0006508 | proteolysis | 22.2222 | 4 | yes |
| GO:0043687 | post-translational protein modification | 22.2222 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 22.2222 | 6 | yes |
| GO:0009967 | positive regulation of signal transduction | 22.2222 | 5 | no |
| GO:0043066 | negative regulation of apoptotic process | 22.2222 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 22.2222 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.2222 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.2222 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.2222 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.2222 | 5 | no |
| GO:0051049 | regulation of transport | 22.2222 | 4 | no |
| GO:0060341 | regulation of cellular localization | 22.2222 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.8333 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.8333 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.8333 | 6 | no |
| GO:0043933 | protein-containing complex organization | 20.8333 | 4 | no |
| GO:0033043 | regulation of organelle organization | 20.8333 | 5 | no |
| GO:0019941 | modification-dependent protein catabolic process | 19.4444 | 6 | yes |
| GO:0043632 | modification-dependent macromolecule catabolic process | 19.4444 | 5 | yes |
| GO:0051603 | proteolysis involved in protein catabolic process | 19.4444 | 5 | yes |
| GO:0080134 | regulation of response to stress | 19.4444 | 4 | yes |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 18.0556 | 7 | yes |
| GO:0032446 | protein modification by small protein conjugation | 18.0556 | 7 | yes |
| GO:1901873 | regulation of post-translational protein modification | 15.2778 | 7 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 15.2778 | 8 | yes |
| GO:0080135 | regulation of cellular response to stress | 11.1111 | 4 | yes |
| GO:0070646 | protein modification by small protein removal | 8.3333 | 7 | yes |
| GO:0001701 | in utero embryonic development | 6.9444 | 6 | yes |
| GO:0009416 | response to light stimulus | 6.9444 | 4 | yes |
| GO:0009792 | embryo development ending in birth or egg hatching | 6.9444 | 4 | yes |
| GO:0043009 | chordate embryonic development | 6.9444 | 5 | yes |
| GO:0045116 | protein neddylation | 6.9444 | 8 | yes |
| GO:1901796 | regulation of signal transduction by p53 class mediator | 6.9444 | 6 | yes |
| GO:0000338 | protein deneddylation | 2.7778 | 8 | yes |
| GO:0043516 | regulation of DNA damage response, signal transduction by p53 class mediator | 2.7778 | 5 | yes |
| GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | 2.7778 | 6 | yes |
| GO:2000434 | regulation of protein neddylation | 2.7778 | 9 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NEDD8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
| CEBPE_HUMAN | [view interactions] | Low throughput | no | no |
| PGH2_HUMAN | [view interactions] | Low throughput | no | no |
| MLF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RBX1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ELOB_HUMAN | [view interactions] | Low throughput | no | no |
| ELOC_HUMAN | [view interactions] | Low throughput | no | no |
| IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
| IKBA_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF5_HUMAN | [view interactions] | Low throughput | no | no |
| BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IL1RA_HUMAN | [view interactions] | Low throughput | no | no |
| DDIT3_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB2_HUMAN | [view interactions] | Low throughput | no | no |
| DDB1_HUMAN | [view interactions] | Low throughput | no | yes |
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSN5_HUMAN | [view interactions] | Low throughput | no | yes |
| CSN6_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | Low throughput | no | yes |
| CSN2_HUMAN | [view interactions] | Low throughput | no | yes |
| CSN1_HUMAN | [view interactions] | Low throughput | no | no |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KBTB2_HUMAN | [view interactions] | Low throughput | no | yes |
| CSN7A_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSN7B_HUMAN | [view interactions] | Low throughput | no | yes |
| DET1_HUMAN | [view interactions] | Low throughput | no | no |
| CSN8_HUMAN | [view interactions] | Low throughput | no | yes |
| CUL2_HUMAN | [view interactions] | Low throughput | no | yes |
| CSN9_HUMAN | [view interactions] | Low throughput | no | yes |
| CSN4_HUMAN | [view interactions] | Low throughput | no | yes |
| BTBD1_HUMAN | [view interactions] | High throughput | no | yes |
| FEM1B_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SPN90_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KLH12_HUMAN | [view interactions] | High throughput | no | no |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| IRF2_HUMAN | [view interactions] | High throughput | no | yes |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| WRP73_HUMAN | [view interactions] | High throughput | no | no |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| PAHX_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| CSN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| ARF4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PXL2B_HUMAN | [view interactions] | High throughput | no | yes |
| NJMU_HUMAN | [view interactions] | High throughput | no | yes |
| SOSB2_HUMAN | [view interactions] | High throughput | no | no |
| FRS3_HUMAN | [view interactions] | High throughput | no | no |
| A2MG_HUMAN | [view interactions] | High throughput | no | yes |
| ACY2_HUMAN | [view interactions] | High throughput | no | no |
| DOPO_HUMAN | [view interactions] | High throughput | no | no |
| TOR1A_HUMAN | [view interactions] | High throughput | no | yes |
| GARS_HUMAN | [view interactions] | High throughput | no | yes |
| GLE1_HUMAN | [view interactions] | High throughput | no | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| HEXB_HUMAN | [view interactions] | High throughput | no | no |
| HXD10_HUMAN | [view interactions] | High throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| NOS3_HUMAN | [view interactions] | High throughput | no | no |
| PEX1_HUMAN | [view interactions] | High throughput | no | no |
| PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYUB_HUMAN | [view interactions] | High throughput | no | yes |
| TTHY_HUMAN | [view interactions] | High throughput | no | no |
| UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYYC_HUMAN | [view interactions] | High throughput | no | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| PEX26_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABRX2_HUMAN | [view interactions] | High throughput | no | yes |
| DCNL1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLH13_HUMAN | [view interactions] | High throughput | no | no |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| CRBN_HUMAN | [view interactions] | High throughput | no | yes |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| RON_HUMAN | [view interactions] | High throughput | no | yes |
| SWAP1_HUMAN | [view interactions] | High throughput | no | no |
| MCPH1_HUMAN | [view interactions] | High throughput | no | yes |
| FAD1_HUMAN | [view interactions] | High throughput | no | yes |
| K2C80_HUMAN | [view interactions] | High throughput | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDA1_HUMAN | [view interactions] | High throughput | no | yes |
| ERCC8_HUMAN | [view interactions] | High throughput | no | no |
| DCAF1_HUMAN | [view interactions] | High throughput | no | yes |
| LRC14_HUMAN | [view interactions] | High throughput | no | no |
| COP1_HUMAN | [view interactions] | High throughput | no | no |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX17_HUMAN | [view interactions] | High throughput | no | no |
| KLH42_HUMAN | [view interactions] | High throughput | no | yes |
| KLH18_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP2_HUMAN | [view interactions] | High throughput | no | no |
| DCAF8_HUMAN | [view interactions] | High throughput | no | yes |
| ERCC6_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBXW4_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| KLH15_HUMAN | [view interactions] | High throughput | no | yes |
| SRP14_HUMAN | [view interactions] | High throughput | no | no |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| IBTK_HUMAN | [view interactions] | High throughput | no | yes |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| DC4L2_HUMAN | [view interactions] | High throughput | no | no |
| PHIP_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOCS2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MAFB_HUMAN | [view interactions] | High throughput | no | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| INSI1_HUMAN | [view interactions] | High throughput | no | no |
| INSI2_HUMAN | [view interactions] | High throughput | no | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR39_HUMAN | [view interactions] | High throughput | no | no |
| DENR_HUMAN | [view interactions] | High throughput | no | yes |
| SYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NHRF2_HUMAN | [view interactions] | High throughput | no | no |
| HS12A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| POTEF_HUMAN | [view interactions] | High throughput | no | no |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| ASB6_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| KLDC3_HUMAN | [view interactions] | High throughput | no | yes |
| KLHL8_HUMAN | [view interactions] | High throughput | no | no |
| CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
| AP5S1_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRAME_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| FBX42_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NC2B_HUMAN | [view interactions] | High throughput | no | yes |
| PB1_HUMAN | [view interactions] | High throughput | no | yes |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| SMCA5_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BABA1_HUMAN | [view interactions] | High throughput | no | yes |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA4_HUMAN | [view interactions] | High throughput | no | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO2_HUMAN | [view interactions] | High throughput | no | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| IMA7_HUMAN | [view interactions] | High throughput | no | yes |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| RO60_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPB1_HUMAN | [view interactions] | High throughput | no | no |
| SYVC_HUMAN | [view interactions] | High throughput | no | yes |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM25_HUMAN | [view interactions] | High throughput | no | yes |
| 5NTC_HUMAN | [view interactions] | High throughput | no | yes |
| RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF2_HUMAN | [view interactions] | High throughput | no | yes |
| AMPD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA3_HUMAN | [view interactions] | High throughput | no | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| TSR1_HUMAN | [view interactions] | High throughput | no | no |
| ARI4B_HUMAN | [view interactions] | High throughput | no | yes |
| PP6R3_HUMAN | [view interactions] | High throughput | no | yes |
| 5MP2_HUMAN | [view interactions] | High throughput | no | yes |
| KI21A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| SMRC1_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KBP_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FNBP1_HUMAN | [view interactions] | High throughput | no | yes |
| ADNP_HUMAN | [view interactions] | High throughput | no | yes |
| PHAX_HUMAN | [view interactions] | High throughput | no | yes |
| EMAL4_HUMAN | [view interactions] | High throughput | no | yes |
| WDR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RALY_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| DTL_HUMAN | [view interactions] | High throughput | no | no |
| LLR1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| DDB2_HUMAN | [view interactions] | High throughput | no | yes |
| LCA5_HUMAN | [view interactions] | High throughput | no | no |
| APBB3_HUMAN | [view interactions] | High throughput | no | no |
| KLH10_HUMAN | [view interactions] | High throughput | no | no |
| FBXL5_HUMAN | [view interactions] | High throughput | no | yes |
| FXL14_HUMAN | [view interactions] | High throughput | no | yes |
| FBX7_HUMAN | [view interactions] | High throughput | no | yes |
| HBB_HUMAN | [view interactions] | High throughput | no | no |
| DCA11_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF4_HUMAN | [view interactions] | High throughput | no | yes |
| APBP2_HUMAN | [view interactions] | High throughput | no | yes |
| BTBD2_HUMAN | [view interactions] | High throughput | no | no |