ATX10_HUMAN
Evidence for PS localization
Functions
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ATX10_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 26.6667 | 4 | no |
| GO:0003723 | RNA binding | 26.6667 | 4 | no |
| GO:0000166 | nucleotide binding | 24.4444 | 4 | no |
| GO:0017076 | purine nucleotide binding | 22.2222 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.2222 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.2222 | 4 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 22.2222 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ATX10_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 57.7778 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 51.1111 | 4 | no |
| GO:0010646 | regulation of cell communication | 48.8889 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 48.8889 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.8889 | 4 | no |
| GO:0009966 | regulation of signal transduction | 46.6667 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 46.6667 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 44.4444 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 44.4444 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 44.4444 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 44.4444 | 5 | no |
| GO:0010468 | regulation of gene expression | 42.2222 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 42.2222 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 42.2222 | 5 | no |
| GO:0006996 | organelle organization | 37.7778 | 4 | yes |
| GO:0043067 | regulation of programmed cell death | 37.7778 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 35.5556 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 35.5556 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 35.5556 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 35.5556 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 35.5556 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 35.5556 | 5 | no |
| GO:0031399 | regulation of protein modification process | 35.5556 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 35.5556 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 33.3333 | 5 | no |
| GO:0023056 | positive regulation of signaling | 33.3333 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:0036211 | protein modification process | 33.3333 | 4 | no |
| GO:0043412 | macromolecule modification | 33.3333 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 33.3333 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 33.3333 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 33.3333 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 33.3333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 31.1111 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 31.1111 | 7 | no |
| GO:0008104 | protein localization | 31.1111 | 4 | no |
| GO:0009894 | regulation of catabolic process | 31.1111 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 31.1111 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 31.1111 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 31.1111 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 31.1111 | 5 | no |
| GO:0023057 | negative regulation of signaling | 31.1111 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 31.1111 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 31.1111 | 5 | no |
| GO:0022607 | cellular component assembly | 28.8889 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 26.6667 | 4 | no |
| GO:0060341 | regulation of cellular localization | 26.6667 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.6667 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.6667 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.6667 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 26.6667 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.4444 | 5 | no |
| GO:0009057 | macromolecule catabolic process | 24.4444 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 24.4444 | 7 | no |
| GO:0032880 | regulation of protein localization | 24.4444 | 5 | no |
| GO:0071310 | cellular response to organic substance | 24.4444 | 4 | no |
| GO:0080134 | regulation of response to stress | 24.4444 | 4 | no |
| GO:0030162 | regulation of proteolysis | 24.4444 | 6 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 24.4444 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.4444 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 24.4444 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 22.2222 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.2222 | 4 | no |
| GO:0051049 | regulation of transport | 22.2222 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 22.2222 | 8 | no |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 22.2222 | 7 | no |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 22.2222 | 5 | no |
| GO:0007010 | cytoskeleton organization | 22.2222 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 22.2222 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 22.2222 | 4 | no |
| GO:0030030 | cell projection organization | 15.5556 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 13.3333 | 5 | yes |
| GO:0070925 | organelle assembly | 8.8889 | 5 | yes |
| GO:0031175 | neuron projection development | 6.6667 | 6 | yes |
| GO:0044782 | cilium organization | 6.6667 | 5 | yes |
| GO:0030031 | cell projection assembly | 4.4444 | 5 | yes |
| GO:0060271 | cilium assembly | 4.4444 | 6 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 4.4444 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MYPT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FINC_HUMAN | [view interactions] | Low throughput | no | yes |
| RT16_HUMAN | [view interactions] | Low throughput | no | yes |
| GLSK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GOGA1_HUMAN | [view interactions] | Low throughput | no | yes |
| ABCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| LAMB3_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIM26_HUMAN | [view interactions] | High throughput | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| VGFR2_HUMAN | [view interactions] | High throughput | no | no |
| SHIP1_HUMAN | [view interactions] | High throughput | no | no |
| TXK_HUMAN | [view interactions] | High throughput | no | no |
| GATA3_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| PHLA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAF1_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA6_HUMAN | [view interactions] | High throughput | no | no |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| STYL1_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAGD1_HUMAN | [view interactions] | High throughput | no | no |
| TNR14_HUMAN | [view interactions] | High throughput | no | no |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WRP73_HUMAN | [view interactions] | High throughput | no | no |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| BAK_HUMAN | [view interactions] | High throughput | no | no |
| CD1C_HUMAN | [view interactions] | High throughput | no | no |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AF17_HUMAN | [view interactions] | High throughput | no | yes |
| PIAS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN232_HUMAN | [view interactions] | High throughput | no | no |
| CSN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLE1_HUMAN | [view interactions] | High throughput | no | yes |
| SPT22_HUMAN | [view interactions] | High throughput | no | no |
| SKI8_HUMAN | [view interactions] | High throughput | no | yes |
| SPA2L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H32_HUMAN | [view interactions] | High throughput | no | yes |
| UBQLN_HUMAN | [view interactions] | High throughput | no | no |
| C19L2_HUMAN | [view interactions] | High throughput | no | yes |
| LRAT1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPV_HUMAN | [view interactions] | High throughput | no | yes |
| ZN774_HUMAN | [view interactions] | High throughput | no | no |
| HYAL2_HUMAN | [view interactions] | High throughput | no | no |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| MICA2_HUMAN | [view interactions] | High throughput | no | yes |
| SLU7_HUMAN | [view interactions] | High throughput | no | yes |
| UT14A_HUMAN | [view interactions] | High throughput | no | yes |
| LPIN1_HUMAN | [view interactions] | High throughput | no | no |
| MLC1_HUMAN | [view interactions] | High throughput | no | no |
| ZKSC5_HUMAN | [view interactions] | High throughput | no | yes |
| PHF19_HUMAN | [view interactions] | High throughput | no | no |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL3_HUMAN | [view interactions] | High throughput | no | no |
| TWST2_HUMAN | [view interactions] | High throughput | no | no |
| 5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
| PE2R4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBL2_HUMAN | [view interactions] | High throughput | no | no |
| LIMS1_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DSCR9_HUMAN | [view interactions] | High throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| CE152_HUMAN | [view interactions] | High throughput | no | yes |
| CE162_HUMAN | [view interactions] | High throughput | no | yes |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| P5F1B_HUMAN | [view interactions] | High throughput | no | no |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS6_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| TGFR2_HUMAN | [view interactions] | High throughput | no | no |
| CCND1_HUMAN | [view interactions] | High throughput | no | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| CDKN3_HUMAN | [view interactions] | High throughput | no | no |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| VTNC_HUMAN | [view interactions] | High throughput | no | no |
| TFDP2_HUMAN | [view interactions] | High throughput | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOSD1_HUMAN | [view interactions] | High throughput | no | no |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY8_HUMAN | [view interactions] | High throughput | no | no |
| TM171_HUMAN | [view interactions] | High throughput | no | yes |
| BTNL9_HUMAN | [view interactions] | High throughput | no | no |
| NKG2A_HUMAN | [view interactions] | High throughput | no | no |
| TPST2_HUMAN | [view interactions] | High throughput | no | yes |
| F174A_HUMAN | [view interactions] | High throughput | no | yes |
| S1PR4_HUMAN | [view interactions] | High throughput | no | no |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| TNR5_HUMAN | [view interactions] | High throughput | no | no |
| CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| PEG10_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| SMCA4_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| MEN1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP36_HUMAN | [view interactions] | High throughput | no | yes |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDK12_HUMAN | [view interactions] | High throughput | no | yes |
| SLD5_HUMAN | [view interactions] | High throughput | no | yes |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| MTEF3_HUMAN | [view interactions] | High throughput | no | no |
| SAE2_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFL1_HUMAN | [view interactions] | High throughput | no | yes |
| XPO5_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| WWP1_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |