ATX10_HUMAN
Evidence for PS localization
Functions
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ATX10_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 27.0270 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 24.3243 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 24.3243 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 24.3243 | 6 | no |
| GO:0017076 | purine nucleotide binding | 24.3243 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 24.3243 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.3243 | 4 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 21.6216 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ATX10_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 59.4595 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 51.3514 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 48.6486 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 48.6486 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.6486 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 48.6486 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 48.6486 | 5 | no |
| GO:0009966 | regulation of signal transduction | 45.9459 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.9459 | 4 | no |
| GO:0010468 | regulation of gene expression | 45.9459 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 45.9459 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 43.2432 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 40.5405 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 40.5405 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 40.5405 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 40.5405 | 5 | no |
| GO:0006996 | organelle organization | 37.8378 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 37.8378 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 37.8378 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 35.1351 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 35.1351 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 35.1351 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 35.1351 | 6 | no |
| GO:0036211 | protein modification process | 32.4324 | 4 | no |
| GO:0043412 | macromolecule modification | 32.4324 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 32.4324 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.4324 | 5 | no |
| GO:0031399 | regulation of protein modification process | 32.4324 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 32.4324 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 32.4324 | 6 | no |
| GO:0051128 | regulation of cellular component organization | 29.7297 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 29.7297 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 29.7297 | 5 | no |
| GO:0010941 | regulation of cell death | 29.7297 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 29.7297 | 5 | no |
| GO:0008104 | protein localization | 27.0270 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 27.0270 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 27.0270 | 5 | no |
| GO:0023057 | negative regulation of signaling | 27.0270 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 27.0270 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 27.0270 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 27.0270 | 6 | no |
| GO:0009894 | regulation of catabolic process | 27.0270 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 27.0270 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 27.0270 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 24.3243 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.3243 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.3243 | 5 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 24.3243 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.3243 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 24.3243 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 24.3243 | 6 | no |
| GO:0060548 | negative regulation of cell death | 24.3243 | 5 | no |
| GO:0022607 | cellular component assembly | 21.6216 | 4 | yes |
| GO:0009057 | macromolecule catabolic process | 21.6216 | 4 | no |
| GO:0007010 | cytoskeleton organization | 21.6216 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 21.6216 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.6216 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 21.6216 | 4 | no |
| GO:0071310 | cellular response to organic substance | 21.6216 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 21.6216 | 7 | no |
| GO:0030030 | cell projection organization | 13.5135 | 4 | yes |
| GO:0070925 | organelle assembly | 10.8108 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 10.8108 | 5 | yes |
| GO:0030031 | cell projection assembly | 5.4054 | 5 | yes |
| GO:0031175 | neuron projection development | 5.4054 | 6 | yes |
| GO:0044782 | cilium organization | 5.4054 | 5 | yes |
| GO:0060271 | cilium assembly | 5.4054 | 6 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 5.4054 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| OGT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FINC_HUMAN | [view interactions] | Low throughput | no | yes |
| RT16_HUMAN | [view interactions] | Low throughput | no | yes |
| GLSK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GOGA1_HUMAN | [view interactions] | Low throughput | no | yes |
| ABCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SLD5_HUMAN | [view interactions] | High throughput | no | yes |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| MTEF3_HUMAN | [view interactions] | High throughput | no | no |
| SAE2_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWP1_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| LAMB3_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| VGFR2_HUMAN | [view interactions] | High throughput | no | no |
| SHIP1_HUMAN | [view interactions] | High throughput | no | no |
| TXK_HUMAN | [view interactions] | High throughput | no | no |
| GATA3_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| PHLA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAF1_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA6_HUMAN | [view interactions] | High throughput | no | no |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| STYL1_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAGD1_HUMAN | [view interactions] | High throughput | no | no |
| TNR14_HUMAN | [view interactions] | High throughput | no | no |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WRP73_HUMAN | [view interactions] | High throughput | no | no |
| SAP18_HUMAN | [view interactions] | High throughput | no | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| PIAS1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN232_HUMAN | [view interactions] | High throughput | no | no |
| BAK_HUMAN | [view interactions] | High throughput | no | no |
| TLE1_HUMAN | [view interactions] | High throughput | no | yes |
| AF17_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD1C_HUMAN | [view interactions] | High throughput | no | no |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HYAL2_HUMAN | [view interactions] | High throughput | no | no |
| ZN774_HUMAN | [view interactions] | High throughput | no | no |
| CENPV_HUMAN | [view interactions] | High throughput | no | yes |
| LRAT1_HUMAN | [view interactions] | High throughput | no | yes |
| C19L2_HUMAN | [view interactions] | High throughput | no | yes |
| UBQLN_HUMAN | [view interactions] | High throughput | no | no |
| H32_HUMAN | [view interactions] | High throughput | no | yes |
| SPA2L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TWST2_HUMAN | [view interactions] | High throughput | no | no |
| SPT22_HUMAN | [view interactions] | High throughput | no | no |
| WDR61_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL3_HUMAN | [view interactions] | High throughput | no | no |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| PHF19_HUMAN | [view interactions] | High throughput | no | no |
| ZKSC5_HUMAN | [view interactions] | High throughput | no | yes |
| MLC1_HUMAN | [view interactions] | High throughput | no | no |
| LPIN1_HUMAN | [view interactions] | High throughput | no | no |
| UT14A_HUMAN | [view interactions] | High throughput | no | yes |
| SLU7_HUMAN | [view interactions] | High throughput | no | yes |
| MICA2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| 5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
| PE2R4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBL2_HUMAN | [view interactions] | High throughput | no | no |
| LIMS1_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| CE152_HUMAN | [view interactions] | High throughput | no | yes |
| CE162_HUMAN | [view interactions] | High throughput | no | yes |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| P5F1B_HUMAN | [view interactions] | High throughput | no | no |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS6_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| TGFR2_HUMAN | [view interactions] | High throughput | no | no |
| CCND1_HUMAN | [view interactions] | High throughput | no | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| CDKN3_HUMAN | [view interactions] | High throughput | no | no |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| VTNC_HUMAN | [view interactions] | High throughput | no | no |
| TFDP2_HUMAN | [view interactions] | High throughput | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOSD1_HUMAN | [view interactions] | High throughput | no | no |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY8_HUMAN | [view interactions] | High throughput | no | no |
| TM171_HUMAN | [view interactions] | High throughput | no | yes |
| BTNL9_HUMAN | [view interactions] | High throughput | no | no |
| NKG2A_HUMAN | [view interactions] | High throughput | no | no |
| TPST2_HUMAN | [view interactions] | High throughput | no | yes |
| F174A_HUMAN | [view interactions] | High throughput | no | yes |
| S1PR4_HUMAN | [view interactions] | High throughput | no | no |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| TNR5_HUMAN | [view interactions] | High throughput | no | no |
| CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| PEG10_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| SMCA4_HUMAN | [view interactions] | High throughput | no | yes |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDK12_HUMAN | [view interactions] | High throughput | no | yes |
| 2ABB_HUMAN | [view interactions] | Computational | no | yes |