GRB10_HUMAN
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001450 | MOD_ProDKin_1 | MOD | 147 | 153 | - |
ELMI001463 | MOD_ProDKin_1 | MOD | 473 | 479 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in GRB10_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 36.7647 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 36.7647 | 5 | no |
GO:0005524 | ATP binding | 35.2941 | 5 | no |
GO:0032555 | purine ribonucleotide binding | 35.2941 | 4 | no |
GO:0032559 | adenyl ribonucleotide binding | 35.2941 | 5 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 35.2941 | 4 | no |
GO:0003723 | RNA binding | 29.4118 | 4 | no |
GO:0019900 | kinase binding | 22.0588 | 4 | no |
GO:0019901 | protein kinase binding | 22.0588 | 5 | no |
GO:0030159 | signaling receptor complex adaptor activity | 8.8235 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in GRB10_HUMAN |
---|---|---|---|---|
GO:0060255 | regulation of macromolecule metabolic process | 73.5294 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 72.0588 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 70.5882 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 70.5882 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 69.1176 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 67.6471 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 60.2941 | 4 | yes |
GO:0010646 | regulation of cell communication | 60.2941 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 57.3529 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 55.8824 | 5 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 55.8824 | 5 | no |
GO:0009966 | regulation of signal transduction | 54.4118 | 4 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 54.4118 | 5 | yes |
GO:0010468 | regulation of gene expression | 54.4118 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 52.9412 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 51.4706 | 5 | no |
GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 50.0000 | 5 | yes |
GO:0009892 | negative regulation of metabolic process | 47.0588 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 47.0588 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 45.5882 | 5 | yes |
GO:0048584 | positive regulation of response to stimulus | 44.1176 | 4 | yes |
GO:0051252 | regulation of RNA metabolic process | 42.6471 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 42.6471 | 5 | no |
GO:0071310 | cellular response to organic substance | 42.6471 | 4 | no |
GO:0010647 | positive regulation of cell communication | 42.6471 | 5 | yes |
GO:0023056 | positive regulation of signaling | 42.6471 | 4 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 42.6471 | 5 | yes |
GO:0031399 | regulation of protein modification process | 42.6471 | 6 | no |
GO:0043412 | macromolecule modification | 41.1765 | 4 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 41.1765 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 39.7059 | 6 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 39.7059 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 39.7059 | 6 | no |
GO:0009967 | positive regulation of signal transduction | 39.7059 | 5 | yes |
GO:0051049 | regulation of transport | 39.7059 | 4 | yes |
GO:0006355 | regulation of DNA-templated transcription | 39.7059 | 6 | no |
GO:0036211 | protein modification process | 39.7059 | 4 | no |
GO:0010941 | regulation of cell death | 38.2353 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 38.2353 | 6 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 38.2353 | 5 | yes |
GO:0008104 | protein localization | 36.7647 | 4 | no |
GO:0043067 | regulation of programmed cell death | 36.7647 | 5 | no |
GO:0042325 | regulation of phosphorylation | 36.7647 | 7 | yes |
GO:0022607 | cellular component assembly | 35.2941 | 4 | no |
GO:0042127 | regulation of cell population proliferation | 35.2941 | 4 | no |
GO:0042981 | regulation of apoptotic process | 35.2941 | 6 | no |
GO:0006796 | phosphate-containing compound metabolic process | 35.2941 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 33.8235 | 5 | no |
GO:0060548 | negative regulation of cell death | 33.8235 | 5 | no |
GO:0010648 | negative regulation of cell communication | 33.8235 | 5 | yes |
GO:0023057 | negative regulation of signaling | 33.8235 | 4 | yes |
GO:0048585 | negative regulation of response to stimulus | 33.8235 | 4 | yes |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 32.3529 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 32.3529 | 6 | no |
GO:0045595 | regulation of cell differentiation | 30.8824 | 4 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 30.8824 | 6 | no |
GO:0060341 | regulation of cellular localization | 30.8824 | 4 | no |
GO:0043069 | negative regulation of programmed cell death | 30.8824 | 6 | no |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 30.8824 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 30.8824 | 5 | yes |
GO:0010243 | response to organonitrogen compound | 30.8824 | 4 | yes |
GO:0001932 | regulation of protein phosphorylation | 30.8824 | 7 | no |
GO:0051338 | regulation of transferase activity | 29.4118 | 4 | no |
GO:0009894 | regulation of catabolic process | 29.4118 | 4 | no |
GO:0043066 | negative regulation of apoptotic process | 29.4118 | 7 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 29.4118 | 6 | no |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 29.4118 | 5 | yes |
GO:0010562 | positive regulation of phosphorus metabolic process | 29.4118 | 6 | yes |
GO:0042327 | positive regulation of phosphorylation | 29.4118 | 8 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 29.4118 | 7 | yes |
GO:0051248 | negative regulation of protein metabolic process | 27.9412 | 6 | no |
GO:0010628 | positive regulation of gene expression | 27.9412 | 6 | no |
GO:0032880 | regulation of protein localization | 27.9412 | 5 | no |
GO:0051254 | positive regulation of RNA metabolic process | 27.9412 | 6 | no |
GO:0071702 | organic substance transport | 27.9412 | 4 | no |
GO:0071705 | nitrogen compound transport | 27.9412 | 4 | no |
GO:1901701 | cellular response to oxygen-containing compound | 27.9412 | 4 | no |
GO:2000026 | regulation of multicellular organismal development | 27.9412 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 27.9412 | 4 | yes |
GO:0031401 | positive regulation of protein modification process | 27.9412 | 7 | no |
GO:0043085 | positive regulation of catalytic activity | 26.4706 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 26.4706 | 5 | no |
GO:0006996 | organelle organization | 26.4706 | 4 | no |
GO:0016310 | phosphorylation | 26.4706 | 5 | no |
GO:0043549 | regulation of kinase activity | 25.0000 | 5 | no |
GO:0051726 | regulation of cell cycle | 25.0000 | 4 | no |
GO:0015031 | protein transport | 25.0000 | 4 | no |
GO:0045893 | positive regulation of DNA-templated transcription | 25.0000 | 7 | no |
GO:1902680 | positive regulation of RNA biosynthetic process | 25.0000 | 7 | no |
GO:1903508 | positive regulation of nucleic acid-templated transcription | 25.0000 | 8 | no |
GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
GO:0051094 | positive regulation of developmental process | 25.0000 | 4 | no |
GO:0006468 | protein phosphorylation | 25.0000 | 5 | no |
GO:0006357 | regulation of transcription by RNA polymerase II | 23.5294 | 7 | no |
GO:0006886 | intracellular protein transport | 23.5294 | 4 | no |
GO:0031344 | regulation of cell projection organization | 23.5294 | 5 | no |
GO:0051050 | positive regulation of transport | 23.5294 | 4 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.5294 | 6 | no |
GO:0065003 | protein-containing complex assembly | 23.5294 | 5 | no |
GO:0031329 | regulation of cellular catabolic process | 23.5294 | 5 | no |
GO:0043408 | regulation of MAPK cascade | 23.5294 | 6 | no |
GO:1901699 | cellular response to nitrogen compound | 23.5294 | 4 | no |
GO:0001934 | positive regulation of protein phosphorylation | 23.5294 | 8 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 22.0588 | 4 | no |
GO:0051223 | regulation of protein transport | 22.0588 | 5 | no |
GO:0070201 | regulation of establishment of protein localization | 22.0588 | 6 | no |
GO:0080134 | regulation of response to stress | 22.0588 | 4 | no |
GO:0033043 | regulation of organelle organization | 22.0588 | 5 | no |
GO:0071417 | cellular response to organonitrogen compound | 22.0588 | 4 | no |
GO:0070848 | response to growth factor | 22.0588 | 4 | no |
GO:0071363 | cellular response to growth factor stimulus | 22.0588 | 5 | no |
GO:0051347 | positive regulation of transferase activity | 20.5882 | 5 | no |
GO:0051129 | negative regulation of cellular component organization | 20.5882 | 5 | no |
GO:2000145 | regulation of cell motility | 20.5882 | 4 | no |
GO:0030162 | regulation of proteolysis | 20.5882 | 6 | no |
GO:0014070 | response to organic cyclic compound | 20.5882 | 4 | no |
GO:0016192 | vesicle-mediated transport | 20.5882 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 20.5882 | 4 | no |
GO:0008285 | negative regulation of cell population proliferation | 20.5882 | 5 | no |
GO:0009890 | negative regulation of biosynthetic process | 20.5882 | 5 | yes |
GO:0031327 | negative regulation of cellular biosynthetic process | 20.5882 | 6 | yes |
GO:2000112 | regulation of cellular macromolecule biosynthetic process | 20.5882 | 6 | yes |
GO:0031400 | negative regulation of protein modification process | 20.5882 | 7 | no |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 19.1176 | 6 | yes |
GO:0034762 | regulation of transmembrane transport | 19.1176 | 4 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 14.7059 | 6 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 14.7059 | 7 | yes |
GO:1901652 | response to peptide | 14.7059 | 4 | yes |
GO:0008286 | insulin receptor signaling pathway | 13.2353 | 6 | yes |
GO:0030111 | regulation of Wnt signaling pathway | 13.2353 | 5 | yes |
GO:0042326 | negative regulation of phosphorylation | 13.2353 | 8 | yes |
GO:0051051 | negative regulation of transport | 11.7647 | 4 | yes |
GO:0000165 | MAPK cascade | 10.2941 | 4 | yes |
GO:0006109 | regulation of carbohydrate metabolic process | 10.2941 | 5 | yes |
GO:0043434 | response to peptide hormone | 10.2941 | 4 | yes |
GO:0043467 | regulation of generation of precursor metabolites and energy | 10.2941 | 5 | yes |
GO:0090287 | regulation of cellular response to growth factor stimulus | 10.2941 | 4 | yes |
GO:0010675 | regulation of cellular carbohydrate metabolic process | 8.8235 | 5 | yes |
GO:0032868 | response to insulin | 8.8235 | 5 | yes |
GO:0034763 | negative regulation of transmembrane transport | 8.8235 | 5 | yes |
GO:0048009 | insulin-like growth factor receptor signaling pathway | 8.8235 | 6 | yes |
GO:0005979 | regulation of glycogen biosynthetic process | 7.3529 | 7 | yes |
GO:0010827 | regulation of glucose transmembrane transport | 7.3529 | 5 | yes |
GO:0010962 | regulation of glucan biosynthetic process | 7.3529 | 6 | yes |
GO:0032881 | regulation of polysaccharide metabolic process | 7.3529 | 5 | yes |
GO:0032885 | regulation of polysaccharide biosynthetic process | 7.3529 | 6 | yes |
GO:0043255 | regulation of carbohydrate biosynthetic process | 7.3529 | 5 | yes |
GO:0046324 | regulation of glucose import | 7.3529 | 6 | yes |
GO:0070371 | ERK1 and ERK2 cascade | 7.3529 | 5 | yes |
GO:0070873 | regulation of glycogen metabolic process | 7.3529 | 6 | yes |
GO:0030178 | negative regulation of Wnt signaling pathway | 5.8824 | 6 | yes |
GO:0046626 | regulation of insulin receptor signaling pathway | 5.8824 | 5 | yes |
GO:0120162 | positive regulation of cold-induced thermogenesis | 5.8824 | 4 | yes |
GO:1900076 | regulation of cellular response to insulin stimulus | 5.8824 | 4 | yes |
GO:0010467 | gene expression | 4.4118 | 4 | yes |
GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway | 4.4118 | 5 | yes |
GO:0046627 | negative regulation of insulin receptor signaling pathway | 4.4118 | 6 | yes |
GO:1900077 | negative regulation of cellular response to insulin stimulus | 4.4118 | 5 | yes |
GO:2000113 | negative regulation of cellular macromolecule biosynthetic process | 4.4118 | 7 | yes |
GO:0010677 | negative regulation of cellular carbohydrate metabolic process | 2.9412 | 6 | yes |
GO:0010829 | negative regulation of glucose transmembrane transport | 2.9412 | 6 | yes |
GO:0014812 | muscle cell migration | 2.9412 | 4 | yes |
GO:0014909 | smooth muscle cell migration | 2.9412 | 5 | yes |
GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway | 2.9412 | 6 | yes |
GO:0045719 | negative regulation of glycogen biosynthetic process | 2.9412 | 7 | yes |
GO:0045912 | negative regulation of carbohydrate metabolic process | 2.9412 | 5 | yes |
GO:0046325 | negative regulation of glucose import | 2.9412 | 7 | yes |
GO:0070874 | negative regulation of glycogen metabolic process | 2.9412 | 6 | yes |
GO:1904738 | vascular associated smooth muscle cell migration | 2.9412 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in GRB10_HUMAN |
---|---|---|---|---|
DOID:0050686 | organ system cancer | 4.4118 | 3 | no |
DOID:331 | central nervous system disease | 4.4118 | 3 | no |
DOID:10595 | Charcot-Marie-Tooth disease | 2.9412 | 6 | no |
DOID:1289 | neurodegenerative disease | 2.9412 | 4 | no |
DOID:231 | motor neuron disease | 2.9412 | 5 | no |
DOID:440 | neuromuscular disease | 2.9412 | 5 | no |
DOID:574 | peripheral nervous system disease | 2.9412 | 3 | no |
DOID:870 | neuropathy | 2.9412 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
EPHB1_HUMAN | [view interactions] | Low throughput | no | no |
1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PGFRB_HUMAN | [view interactions] | Low throughput | no | yes |
P85A_HUMAN | [view interactions] | Low throughput | no | yes |
CAV1_HUMAN | [view interactions] | Low throughput | no | no |
RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
KIT_HUMAN | [view interactions] | Low throughput | no | no |
MP2K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RET_HUMAN | [view interactions] | Low throughput | no | yes |
GRB10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GHR_HUMAN | [view interactions] | Low throughput | no | yes |
JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IRS2_HUMAN | [view interactions] | Low throughput | no | yes |
IRS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CNOT9_HUMAN | [view interactions] | Low throughput | no | yes |
NED4L_HUMAN | [view interactions] | Low throughput | no | yes |
IL2RG_HUMAN | [view interactions] | Low throughput | no | no |
IL4RA_HUMAN | [view interactions] | Low throughput | no | no |
SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCNA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NTRK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CHFR_HUMAN | [view interactions] | Low throughput | no | no |
FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
INSR_HUMAN | [view interactions] | Low throughput | no | yes |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
GGYF1_HUMAN | [view interactions] | Low throughput | no | yes |
GGYF2_HUMAN | [view interactions] | Low throughput | no | yes |
FLT3_HUMAN | [view interactions] | Low throughput | no | no |
AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
H14_HUMAN | [view interactions] | High throughput | no | yes |
H13_HUMAN | [view interactions] | High throughput | no | no |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H12_HUMAN | [view interactions] | High throughput | no | yes |
HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP77_HUMAN | [view interactions] | High throughput | no | no |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
CADH3_HUMAN | [view interactions] | High throughput | no | no |
2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NOP2_HUMAN | [view interactions] | High throughput | no | yes |
RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP11_HUMAN | [view interactions] | High throughput | no | yes |
RL37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
2ABA_HUMAN | [view interactions] | High throughput | no | yes |
PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBM39_HUMAN | [view interactions] | High throughput | no | yes |
CUL7_HUMAN | [view interactions] | High throughput | no | yes |
SC23B_HUMAN | [view interactions] | High throughput | no | yes |
TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
SRSF7_HUMAN | [view interactions] | High throughput | no | yes |
2ABD_HUMAN | [view interactions] | High throughput | no | yes |
DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MIA40_HUMAN | [view interactions] | High throughput | no | yes |
TFB1M_HUMAN | [view interactions] | High throughput | no | yes |
H1X_HUMAN | [view interactions] | High throughput | no | yes |
HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EBP2_HUMAN | [view interactions] | High throughput | no | yes |
GRWD1_HUMAN | [view interactions] | High throughput | no | no |
MK67I_HUMAN | [view interactions] | High throughput | no | yes |
GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
DDX24_HUMAN | [view interactions] | High throughput | no | yes |
GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
WDR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EXOS3_HUMAN | [view interactions] | High throughput | no | yes |
RBM28_HUMAN | [view interactions] | High throughput | no | yes |
AKP8L_HUMAN | [view interactions] | High throughput | no | yes |
G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RCL1_HUMAN | [view interactions] | High throughput | no | no |
EXOS1_HUMAN | [view interactions] | High throughput | no | yes |
IF2B2_HUMAN | [view interactions] | High throughput | no | yes |
ANR28_HUMAN | [view interactions] | High throughput | no | no |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TOP1_HUMAN | [view interactions] | High throughput | no | yes |
PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AL1A3_HUMAN | [view interactions] | High throughput | no | yes |
DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FAT1_HUMAN | [view interactions] | High throughput | no | yes |
SART3_HUMAN | [view interactions] | High throughput | no | yes |
CDC73_HUMAN | [view interactions] | High throughput | no | yes |
SPB1_HUMAN | [view interactions] | High throughput | no | yes |
PAF1_HUMAN | [view interactions] | High throughput | no | yes |
WDR61_HUMAN | [view interactions] | High throughput | no | yes |
L10K_HUMAN | [view interactions] | High throughput | no | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EHD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MK13_HUMAN | [view interactions] | High throughput | no | yes |
PGM1_HUMAN | [view interactions] | High throughput | no | no |
PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
ZDH17_HUMAN | [view interactions] | High throughput | no | yes |
RCAN3_HUMAN | [view interactions] | High throughput | no | no |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TXK_HUMAN | [view interactions] | High throughput | no | no |
PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IMA4_HUMAN | [view interactions] | High throughput | no | yes |
SNAT_HUMAN | [view interactions] | High throughput | no | no |
BLK_HUMAN | [view interactions] | High throughput | no | no |
SYFM_HUMAN | [view interactions] | High throughput | no | yes |
TEKT4_HUMAN | [view interactions] | High throughput | no | no |
ZMY19_HUMAN | [view interactions] | High throughput | no | yes |
AP4AT_HUMAN | [view interactions] | High throughput | no | no |
IKBD_HUMAN | [view interactions] | High throughput | no | no |
TNK1_HUMAN | [view interactions] | High throughput | no | yes |
KANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI55_HUMAN | [view interactions] | High throughput | no | no |
TRI63_HUMAN | [view interactions] | High throughput | no | no |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WDR59_HUMAN | [view interactions] | High throughput | no | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INS_HUMAN | [view interactions] | High throughput | no | no |
DDX58_HUMAN | [view interactions] | High throughput | no | yes |
AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
MAGA3_HUMAN | [view interactions] | High throughput | no | no |
S10A2_HUMAN | [view interactions] | High throughput | no | no |
RILP_HUMAN | [view interactions] | High throughput | no | no |
NRN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CCYL1_HUMAN | [view interactions] | High throughput | no | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ERBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEN5B_HUMAN | [view interactions] | High throughput | no | yes |
SYNC_HUMAN | [view interactions] | High throughput | no | yes |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MEG10_HUMAN | [view interactions] | High throughput | no | no |
NOA1_HUMAN | [view interactions] | High throughput | no | yes |
IQCB1_HUMAN | [view interactions] | High throughput | no | no |
1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KI67_HUMAN | [view interactions] | High throughput | no | no |
RPOM_HUMAN | [view interactions] | High throughput | no | yes |
CRTAP_HUMAN | [view interactions] | High throughput | no | yes |
HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GDNF_HUMAN | [view interactions] | Computational | no | yes |
PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PDGFB_HUMAN | [view interactions] | Computational | no | yes |
GRB7_HUMAN | [view interactions] | Computational | no | no |
DOK1_HUMAN | [view interactions] | Computational | no | yes |
ATF4_HUMAN | [view interactions] | Computational | no | no |
IGF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
SHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GFRA1_HUMAN | [view interactions] | Computational | no | no |