GRB10_HUMAN
Evidence for PS localization
Functions
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI001450 | MOD_ProDKin_1 | MOD | 147 | 153 | - |
| ELMI001463 | MOD_ProDKin_1 | MOD | 473 | 479 | - |
| ELMI001450 | MOD_ProDKin_1 | MOD | 147 | 153 | - |
| ELMI001463 | MOD_ProDKin_1 | MOD | 473 | 479 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GRB10_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 35.8209 | 4 | no |
| GO:0043168 | anion binding | 35.8209 | 4 | no |
| GO:0005524 | ATP binding | 34.3284 | 5 | no |
| GO:0017076 | purine nucleotide binding | 34.3284 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 34.3284 | 6 | no |
| GO:0032555 | purine ribonucleotide binding | 34.3284 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 34.3284 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.3284 | 4 | no |
| GO:0003723 | RNA binding | 29.8507 | 4 | no |
| GO:0031625 | ubiquitin protein ligase binding | 20.8955 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 20.8955 | 4 | no |
| GO:0019900 | kinase binding | 20.8955 | 4 | no |
| GO:0019901 | protein kinase binding | 20.8955 | 5 | no |
| GO:0030159 | signaling receptor complex adaptor activity | 8.9552 | 4 | yes |
| GO:0005158 | insulin receptor binding | 7.4627 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GRB10_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 71.6418 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 71.6418 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 68.6567 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 67.1642 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 64.1791 | 4 | yes |
| GO:0010646 | regulation of cell communication | 61.1940 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 58.2090 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 58.2090 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 56.7164 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 56.7164 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 56.7164 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 52.2388 | 5 | no |
| GO:0010468 | regulation of gene expression | 50.7463 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 50.7463 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 50.7463 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 47.7612 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 47.7612 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 47.7612 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 44.7761 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 44.7761 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 43.2836 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 43.2836 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 43.2836 | 5 | no |
| GO:0043412 | macromolecule modification | 43.2836 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 41.7910 | 5 | yes |
| GO:0036211 | protein modification process | 41.7910 | 4 | no |
| GO:0031399 | regulation of protein modification process | 40.2985 | 6 | no |
| GO:0008104 | protein localization | 40.2985 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 38.8060 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 38.8060 | 5 | no |
| GO:0023057 | negative regulation of signaling | 37.3134 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 37.3134 | 5 | yes |
| GO:0048585 | negative regulation of response to stimulus | 37.3134 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 37.3134 | 5 | no |
| GO:0022607 | cellular component assembly | 37.3134 | 4 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 37.3134 | 6 | no |
| GO:0010648 | negative regulation of cell communication | 35.8209 | 5 | yes |
| GO:0051049 | regulation of transport | 35.8209 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 35.8209 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 35.8209 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 35.8209 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 35.8209 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 34.3284 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 34.3284 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 32.8358 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 32.8358 | 5 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 32.8358 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 32.8358 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 31.3433 | 7 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 31.3433 | 6 | no |
| GO:0045595 | regulation of cell differentiation | 31.3433 | 4 | no |
| GO:0060341 | regulation of cellular localization | 31.3433 | 4 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 29.8507 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 29.8507 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 29.8507 | 4 | no |
| GO:0043069 | negative regulation of programmed cell death | 29.8507 | 5 | no |
| GO:0007169 | cell surface receptor protein tyrosine kinase signaling pathway | 28.3582 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 28.3582 | 6 | no |
| GO:0043066 | negative regulation of apoptotic process | 28.3582 | 6 | no |
| GO:0071310 | cellular response to organic substance | 28.3582 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 28.3582 | 7 | no |
| GO:0032880 | regulation of protein localization | 28.3582 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.8657 | 5 | yes |
| GO:0010243 | response to organonitrogen compound | 26.8657 | 4 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.8657 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.8657 | 6 | yes |
| GO:0043933 | protein-containing complex organization | 26.8657 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 26.8657 | 5 | no |
| GO:0071702 | organic substance transport | 26.8657 | 4 | no |
| GO:0071705 | nitrogen compound transport | 26.8657 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 26.8657 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 25.3731 | 6 | yes |
| GO:0042327 | positive regulation of phosphorylation | 25.3731 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 25.3731 | 7 | yes |
| GO:0010628 | positive regulation of gene expression | 25.3731 | 7 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 25.3731 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 25.3731 | 4 | no |
| GO:0006996 | organelle organization | 25.3731 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 25.3731 | 7 | no |
| GO:0044087 | regulation of cellular component biogenesis | 25.3731 | 4 | no |
| GO:0141124 | intracellular signaling cassette | 23.8806 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 23.8806 | 5 | no |
| GO:0006468 | protein phosphorylation | 23.8806 | 5 | no |
| GO:0016310 | phosphorylation | 23.8806 | 5 | no |
| GO:0015031 | protein transport | 23.8806 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 22.3881 | 8 | no |
| GO:0030030 | cell projection organization | 22.3881 | 4 | no |
| GO:0043408 | regulation of MAPK cascade | 22.3881 | 6 | no |
| GO:0080134 | regulation of response to stress | 22.3881 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 22.3881 | 4 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 22.3881 | 8 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 22.3881 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.3881 | 4 | no |
| GO:0030162 | regulation of proteolysis | 20.8955 | 6 | no |
| GO:0031400 | negative regulation of protein modification process | 20.8955 | 7 | no |
| GO:0051338 | regulation of transferase activity | 20.8955 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 20.8955 | 5 | no |
| GO:0051726 | regulation of cell cycle | 20.8955 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.8955 | 6 | no |
| GO:0008285 | negative regulation of cell population proliferation | 20.8955 | 5 | no |
| GO:0033043 | regulation of organelle organization | 20.8955 | 5 | no |
| GO:0060284 | regulation of cell development | 20.8955 | 5 | no |
| GO:0034762 | regulation of transmembrane transport | 19.4030 | 4 | yes |
| GO:0009059 | macromolecule biosynthetic process | 16.4179 | 4 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 14.9254 | 6 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 14.9254 | 7 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 13.4328 | 5 | yes |
| GO:0042326 | negative regulation of phosphorylation | 13.4328 | 8 | yes |
| GO:0051051 | negative regulation of transport | 13.4328 | 4 | yes |
| GO:0008286 | insulin receptor signaling pathway | 11.9403 | 6 | yes |
| GO:0034763 | negative regulation of transmembrane transport | 11.9403 | 5 | yes |
| GO:0043434 | response to peptide hormone | 11.9403 | 4 | yes |
| GO:0048009 | insulin-like growth factor receptor signaling pathway | 11.9403 | 6 | yes |
| GO:0090287 | regulation of cellular response to growth factor stimulus | 11.9403 | 4 | yes |
| GO:0000165 | MAPK cascade | 10.4478 | 5 | yes |
| GO:0006109 | regulation of carbohydrate metabolic process | 10.4478 | 5 | yes |
| GO:0032868 | response to insulin | 10.4478 | 5 | yes |
| GO:0043467 | regulation of generation of precursor metabolites and energy | 8.9552 | 5 | yes |
| GO:0005979 | regulation of glycogen biosynthetic process | 5.9701 | 7 | yes |
| GO:0010827 | regulation of glucose transmembrane transport | 5.9701 | 5 | yes |
| GO:0010962 | regulation of glucan biosynthetic process | 5.9701 | 7 | yes |
| GO:0032881 | regulation of polysaccharide metabolic process | 5.9701 | 5 | yes |
| GO:0032885 | regulation of polysaccharide biosynthetic process | 5.9701 | 6 | yes |
| GO:0043255 | regulation of carbohydrate biosynthetic process | 5.9701 | 5 | yes |
| GO:0046324 | regulation of glucose import | 5.9701 | 6 | yes |
| GO:0046626 | regulation of insulin receptor signaling pathway | 5.9701 | 5 | yes |
| GO:0070371 | ERK1 and ERK2 cascade | 5.9701 | 6 | yes |
| GO:0070873 | regulation of glycogen metabolic process | 5.9701 | 6 | yes |
| GO:0120161 | regulation of cold-induced thermogenesis | 5.9701 | 4 | yes |
| GO:0120162 | positive regulation of cold-induced thermogenesis | 5.9701 | 5 | yes |
| GO:1900076 | regulation of cellular response to insulin stimulus | 5.9701 | 4 | yes |
| GO:0010467 | gene expression | 4.4776 | 5 | yes |
| GO:0030178 | negative regulation of Wnt signaling pathway | 4.4776 | 6 | yes |
| GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway | 4.4776 | 5 | yes |
| GO:0045912 | negative regulation of carbohydrate metabolic process | 4.4776 | 5 | yes |
| GO:0046627 | negative regulation of insulin receptor signaling pathway | 4.4776 | 6 | yes |
| GO:1900077 | negative regulation of cellular response to insulin stimulus | 4.4776 | 5 | yes |
| GO:0010829 | negative regulation of glucose transmembrane transport | 2.9851 | 6 | yes |
| GO:0014812 | muscle cell migration | 2.9851 | 4 | yes |
| GO:0014909 | smooth muscle cell migration | 2.9851 | 5 | yes |
| GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway | 2.9851 | 6 | yes |
| GO:0045719 | negative regulation of glycogen biosynthetic process | 2.9851 | 7 | yes |
| GO:0046325 | negative regulation of glucose import | 2.9851 | 7 | yes |
| GO:0070874 | negative regulation of glycogen metabolic process | 2.9851 | 6 | yes |
| GO:1904738 | vascular associated smooth muscle cell migration | 2.9851 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CAV1_HUMAN | [view interactions] | Low throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| KIT_HUMAN | [view interactions] | Low throughput | no | no |
| MP2K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RET_HUMAN | [view interactions] | Low throughput | no | yes |
| GRB10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GHR_HUMAN | [view interactions] | Low throughput | no | yes |
| JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IRS2_HUMAN | [view interactions] | Low throughput | no | yes |
| IRS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CNOT9_HUMAN | [view interactions] | Low throughput | no | yes |
| NED4L_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IL2RG_HUMAN | [view interactions] | Low throughput | no | no |
| IL4RA_HUMAN | [view interactions] | Low throughput | no | no |
| SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NTRK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHFR_HUMAN | [view interactions] | Low throughput | no | no |
| FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| INSR_HUMAN | [view interactions] | Low throughput | no | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| GGYF1_HUMAN | [view interactions] | Low throughput | no | yes |
| GGYF2_HUMAN | [view interactions] | Low throughput | no | yes |
| FLT3_HUMAN | [view interactions] | Low throughput | no | no |
| EPHB1_HUMAN | [view interactions] | Low throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PGFRB_HUMAN | [view interactions] | Low throughput | no | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXK_HUMAN | [view interactions] | High throughput | no | no |
| PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA4_HUMAN | [view interactions] | High throughput | no | yes |
| SNAT_HUMAN | [view interactions] | High throughput | no | no |
| BLK_HUMAN | [view interactions] | High throughput | no | no |
| SYFM_HUMAN | [view interactions] | High throughput | no | yes |
| TEKT4_HUMAN | [view interactions] | High throughput | no | no |
| ZMY19_HUMAN | [view interactions] | High throughput | no | yes |
| AP4AT_HUMAN | [view interactions] | High throughput | no | no |
| IKBD_HUMAN | [view interactions] | High throughput | no | no |
| TNK1_HUMAN | [view interactions] | High throughput | no | yes |
| KANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WDR59_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| S10A2_HUMAN | [view interactions] | High throughput | no | no |
| RILP_HUMAN | [view interactions] | High throughput | no | no |
| NRN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| CCNB1_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEN5B_HUMAN | [view interactions] | High throughput | no | yes |
| SYNC_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEG10_HUMAN | [view interactions] | High throughput | no | no |
| NOA1_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| IF2B2_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS1_HUMAN | [view interactions] | High throughput | no | yes |
| RCL1_HUMAN | [view interactions] | High throughput | no | no |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKP8L_HUMAN | [view interactions] | High throughput | no | yes |
| RBM28_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS3_HUMAN | [view interactions] | High throughput | no | yes |
| WDR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
| MK67I_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| EBP2_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H1X_HUMAN | [view interactions] | High throughput | no | yes |
| TFB1M_HUMAN | [view interactions] | High throughput | no | yes |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2ABD_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF7_HUMAN | [view interactions] | High throughput | no | yes |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| SC23B_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2ABA_HUMAN | [view interactions] | High throughput | no | yes |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOP2_HUMAN | [view interactions] | High throughput | no | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CADH3_HUMAN | [view interactions] | High throughput | no | no |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| HSP77_HUMAN | [view interactions] | High throughput | no | no |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H12_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H13_HUMAN | [view interactions] | High throughput | no | no |
| H14_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CRTAP_HUMAN | [view interactions] | High throughput | no | yes |
| RPOM_HUMAN | [view interactions] | High throughput | no | yes |
| L10K_HUMAN | [view interactions] | High throughput | no | yes |
| SKI8_HUMAN | [view interactions] | High throughput | no | yes |
| PAF1_HUMAN | [view interactions] | High throughput | no | yes |
| SPB1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| FAT1_HUMAN | [view interactions] | High throughput | no | yes |
| RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| AL1A3_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP1_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANR28_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EHD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK13_HUMAN | [view interactions] | High throughput | no | yes |
| PGM1_HUMAN | [view interactions] | High throughput | no | no |
| PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDH17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RCAN3_HUMAN | [view interactions] | High throughput | no | no |