Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IRS1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
1043 Ser Tyr Type2diabetesmellitus(T2D) -
1095 Cys Tyr Type2diabetesmellitus(T2D) -

Linear motifs

ELM instance Name Type Start End Partner
ELMI003065 DOC_MAPK_JIP1_4 DOC 857 863 -
ELMI002011 DOC_WW_Pin1_4 DOC 431 436 -
ELMI003692 LIG_SH2_GRB2like LIG 896 899 -
ELMI003065 DOC_MAPK_JIP1_4 DOC 857 863 -
ELMI002011 DOC_WW_Pin1_4 DOC 431 436 -
ELMI003692 LIG_SH2_GRB2like LIG 896 899 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in IRS1_HUMAN
GO:0019900 kinase binding 33.7838 4 yes
GO:0019901 protein kinase binding 32.4324 5 yes
GO:0043168 anion binding 29.7297 4 no
GO:0000166 nucleotide binding 27.0270 4 no
GO:0017076 purine nucleotide binding 27.0270 5 no
GO:0032555 purine ribonucleotide binding 27.0270 4 no
GO:0035639 purine ribonucleoside triphosphate binding 27.0270 4 no
GO:0005524 ATP binding 24.3243 5 no
GO:0016301 kinase activity 24.3243 4 no
GO:0030554 adenyl nucleotide binding 24.3243 6 no
GO:0032559 adenyl ribonucleotide binding 24.3243 5 no
GO:0003723 RNA binding 24.3243 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 22.9730 4 no
GO:0045309 protein phosphorylated amino acid binding 18.9189 4 yes
GO:1990782 protein tyrosine kinase binding 16.2162 6 yes
GO:0030971 receptor tyrosine kinase binding 14.8649 4 yes
GO:0001784 phosphotyrosine residue binding 12.1622 5 yes
GO:0030159 signaling receptor complex adaptor activity 10.8108 4 yes
GO:0005158 insulin receptor binding 9.4595 4 yes
GO:0005159 insulin-like growth factor receptor binding 8.1081 4 yes
GO:0042169 SH2 domain binding 8.1081 4 yes
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 5.4054 5 yes
GO:0005080 protein kinase C binding 5.4054 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in IRS1_HUMAN
GO:0048523 negative regulation of cellular process 77.0270 4 yes
GO:0048522 positive regulation of cellular process 75.6757 4 yes
GO:0060255 regulation of macromolecule metabolic process 72.9730 4 yes
GO:0031323 regulation of cellular metabolic process 72.9730 4 yes
GO:0080090 regulation of primary metabolic process 71.6216 4 yes
GO:0010646 regulation of cell communication 71.6216 4 yes
GO:0009966 regulation of signal transduction 68.9189 4 yes
GO:0031326 regulation of cellular biosynthetic process 62.1622 5 yes
GO:0009889 regulation of biosynthetic process 62.1622 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 60.8108 5 yes
GO:1902531 regulation of intracellular signal transduction 56.7568 5 yes
GO:0010468 regulation of gene expression 55.4054 6 no
GO:0051128 regulation of cellular component organization 55.4054 4 no
GO:0009892 negative regulation of metabolic process 54.0541 4 no
GO:0009893 positive regulation of metabolic process 54.0541 4 yes
GO:0048584 positive regulation of response to stimulus 52.7027 4 yes
GO:0051246 regulation of protein metabolic process 52.7027 5 no
GO:0010605 negative regulation of macromolecule metabolic process 51.3514 5 no
GO:0036211 protein modification process 51.3514 4 no
GO:0043412 macromolecule modification 51.3514 4 no
GO:0031324 negative regulation of cellular metabolic process 50.0000 5 no
GO:0010604 positive regulation of macromolecule metabolic process 50.0000 5 yes
GO:0009967 positive regulation of signal transduction 48.6486 5 yes
GO:0010647 positive regulation of cell communication 48.6486 5 yes
GO:0023056 positive regulation of signaling 48.6486 4 yes
GO:0031325 positive regulation of cellular metabolic process 44.5946 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 44.5946 5 no
GO:0048585 negative regulation of response to stimulus 43.2432 4 yes
GO:1902533 positive regulation of intracellular signal transduction 41.8919 6 yes
GO:0051252 regulation of RNA metabolic process 41.8919 5 no
GO:0010648 negative regulation of cell communication 41.8919 5 yes
GO:0023057 negative regulation of signaling 41.8919 4 yes
GO:0060341 regulation of cellular localization 40.5405 4 yes
GO:0009968 negative regulation of signal transduction 40.5405 5 yes
GO:0051049 regulation of transport 39.1892 4 yes
GO:0031399 regulation of protein modification process 39.1892 6 no
GO:0032880 regulation of protein localization 37.8378 5 yes
GO:0071310 cellular response to organic substance 37.8378 4 yes
GO:0006355 regulation of DNA-templated transcription 37.8378 7 no
GO:0042981 regulation of apoptotic process 37.8378 5 no
GO:0043067 regulation of programmed cell death 37.8378 4 no
GO:2001141 regulation of RNA biosynthetic process 37.8378 6 no
GO:0006996 organelle organization 37.8378 4 no
GO:0031328 positive regulation of cellular biosynthetic process 36.4865 6 yes
GO:0042127 regulation of cell population proliferation 36.4865 4 yes
GO:0051247 positive regulation of protein metabolic process 36.4865 6 no
GO:0006796 phosphate-containing compound metabolic process 36.4865 4 no
GO:0009891 positive regulation of biosynthetic process 36.4865 5 yes
GO:0009894 regulation of catabolic process 36.4865 4 yes
GO:0009890 negative regulation of biosynthetic process 35.1351 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 35.1351 6 no
GO:0031327 negative regulation of cellular biosynthetic process 35.1351 6 no
GO:0019220 regulation of phosphate metabolic process 33.7838 6 no
GO:0051174 regulation of phosphorus metabolic process 33.7838 5 no
GO:0045595 regulation of cell differentiation 33.7838 4 no
GO:0007167 enzyme-linked receptor protein signaling pathway 33.7838 4 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 33.7838 6 yes
GO:0051248 negative regulation of protein metabolic process 32.4324 6 no
GO:0008104 protein localization 32.4324 4 no
GO:0022607 cellular component assembly 31.0811 4 no
GO:1901701 cellular response to oxygen-containing compound 29.7297 4 yes
GO:0042325 regulation of phosphorylation 29.7297 7 no
GO:0051240 positive regulation of multicellular organismal process 29.7297 4 no
GO:0080134 regulation of response to stress 29.7297 4 no
GO:0043066 negative regulation of apoptotic process 29.7297 6 no
GO:0043069 negative regulation of programmed cell death 29.7297 5 no
GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway 29.7297 5 yes
GO:0001932 regulation of protein phosphorylation 28.3784 7 no
GO:0030155 regulation of cell adhesion 28.3784 4 no
GO:0008284 positive regulation of cell population proliferation 28.3784 5 yes
GO:0141124 intracellular signaling cassette 27.0270 4 yes
GO:0043408 regulation of MAPK cascade 27.0270 6 no
GO:0031401 positive regulation of protein modification process 27.0270 7 no
GO:0010243 response to organonitrogen compound 27.0270 4 yes
GO:0002684 positive regulation of immune system process 25.6757 4 no
GO:0030030 cell projection organization 25.6757 4 no
GO:0044087 regulation of cellular component biogenesis 25.6757 4 no
GO:0016310 phosphorylation 25.6757 5 no
GO:0071417 cellular response to organonitrogen compound 24.3243 4 yes
GO:1901699 cellular response to nitrogen compound 24.3243 4 yes
GO:0010628 positive regulation of gene expression 24.3243 7 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 24.3243 5 no
GO:0051130 positive regulation of cellular component organization 24.3243 5 no
GO:1902532 negative regulation of intracellular signal transduction 24.3243 6 no
GO:0006468 protein phosphorylation 24.3243 5 no
GO:0032870 cellular response to hormone stimulus 22.9730 4 yes
GO:0070201 regulation of establishment of protein localization 22.9730 6 yes
GO:0033043 regulation of organelle organization 22.9730 5 no
GO:0031344 regulation of cell projection organization 22.9730 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 22.9730 6 no
GO:0043687 post-translational protein modification 22.9730 5 no
GO:0051094 positive regulation of developmental process 22.9730 4 no
GO:0051726 regulation of cell cycle 22.9730 4 no
GO:0009057 macromolecule catabolic process 22.9730 4 no
GO:0050776 regulation of immune response 22.9730 4 no
GO:0009896 positive regulation of catabolic process 22.9730 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 21.6216 8 no
GO:0043933 protein-containing complex organization 21.6216 4 no
GO:0120036 plasma membrane bounded cell projection organization 21.6216 5 no
GO:0032101 regulation of response to external stimulus 21.6216 4 no
GO:0018193 peptidyl-amino acid modification 21.6216 5 no
GO:1903829 positive regulation of protein localization 21.6216 5 no
GO:0043085 positive regulation of catalytic activity 21.6216 4 no
GO:0010629 negative regulation of gene expression 21.6216 7 no
GO:0051338 regulation of transferase activity 21.6216 4 no
GO:0051050 positive regulation of transport 20.2703 4 yes
GO:0022407 regulation of cell-cell adhesion 20.2703 5 no
GO:0031400 negative regulation of protein modification process 20.2703 7 no
GO:0045785 positive regulation of cell adhesion 20.2703 5 no
GO:0050865 regulation of cell activation 20.2703 4 no
GO:0043410 positive regulation of MAPK cascade 20.2703 7 no
GO:0090304 nucleic acid metabolic process 20.2703 4 no
GO:0010562 positive regulation of phosphorus metabolic process 20.2703 6 no
GO:0042327 positive regulation of phosphorylation 20.2703 8 no
GO:0045937 positive regulation of phosphate metabolic process 20.2703 7 no
GO:2000026 regulation of multicellular organismal development 20.2703 4 no
GO:0033993 response to lipid 18.9189 4 yes
GO:0034762 regulation of transmembrane transport 18.9189 4 yes
GO:0043434 response to peptide hormone 18.9189 4 yes
GO:0031329 regulation of cellular catabolic process 17.5676 5 yes
GO:0051223 regulation of protein transport 17.5676 5 yes
GO:0071375 cellular response to peptide hormone stimulus 17.5676 5 yes
GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 16.2162 6 yes
GO:0008286 insulin receptor signaling pathway 16.2162 6 yes
GO:0071396 cellular response to lipid 14.8649 5 yes
GO:0051051 negative regulation of transport 13.5135 4 yes
GO:1903828 negative regulation of protein localization 13.5135 5 yes
GO:0031331 positive regulation of cellular catabolic process 12.1622 6 yes
GO:0032868 response to insulin 12.1622 5 yes
GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction 12.1622 5 yes
GO:0048009 insulin-like growth factor receptor signaling pathway 12.1622 6 yes
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 12.1622 7 yes
GO:0032869 cellular response to insulin stimulus 10.8108 6 yes
GO:0043467 regulation of generation of precursor metabolites and energy 10.8108 5 yes
GO:0046626 regulation of insulin receptor signaling pathway 10.8108 5 yes
GO:1900076 regulation of cellular response to insulin stimulus 10.8108 4 yes
GO:0046627 negative regulation of insulin receptor signaling pathway 9.4595 6 yes
GO:1900077 negative regulation of cellular response to insulin stimulus 9.4595 5 yes
GO:0006109 regulation of carbohydrate metabolic process 9.4595 5 yes
GO:0019216 regulation of lipid metabolic process 9.4595 5 yes
GO:0019221 cytokine-mediated signaling pathway 9.4595 4 yes
GO:0042593 glucose homeostasis 8.1081 4 yes
GO:0045834 positive regulation of lipid metabolic process 8.1081 5 yes
GO:0046324 regulation of glucose import 8.1081 6 yes
GO:0010827 regulation of glucose transmembrane transport 8.1081 5 yes
GO:0032881 regulation of polysaccharide metabolic process 6.7568 5 yes
GO:0032885 regulation of polysaccharide biosynthetic process 6.7568 6 yes
GO:0043255 regulation of carbohydrate biosynthetic process 6.7568 5 yes
GO:0045913 positive regulation of carbohydrate metabolic process 6.7568 5 yes
GO:0050994 regulation of lipid catabolic process 6.7568 5 yes
GO:0051046 regulation of secretion 6.7568 5 yes
GO:0062012 regulation of small molecule metabolic process 6.7568 4 yes
GO:0062013 positive regulation of small molecule metabolic process 6.7568 5 yes
GO:0070873 regulation of glycogen metabolic process 6.7568 6 yes
GO:1903530 regulation of secretion by cell 6.7568 4 yes
GO:0005979 regulation of glycogen biosynthetic process 6.7568 7 yes
GO:0010962 regulation of glucan biosynthetic process 6.7568 7 yes
GO:0034764 positive regulation of transmembrane transport 5.4054 5 yes
GO:0046326 positive regulation of glucose import 5.4054 7 yes
GO:0046628 positive regulation of insulin receptor signaling pathway 5.4054 6 yes
GO:0046883 regulation of hormone secretion 5.4054 4 yes
GO:0050708 regulation of protein secretion 5.4054 5 yes
GO:0050796 regulation of insulin secretion 5.4054 6 yes
GO:0090087 regulation of peptide transport 5.4054 5 yes
GO:0090276 regulation of peptide hormone secretion 5.4054 5 yes
GO:1900078 positive regulation of cellular response to insulin stimulus 5.4054 5 yes
GO:1904950 negative regulation of establishment of protein localization 5.4054 6 yes
GO:0002791 regulation of peptide secretion 5.4054 6 yes
GO:0010828 positive regulation of glucose transmembrane transport 5.4054 6 yes
GO:0031998 regulation of fatty acid beta-oxidation 4.0541 6 yes
GO:0045725 positive regulation of glycogen biosynthetic process 4.0541 7 yes
GO:0046320 regulation of fatty acid oxidation 4.0541 7 yes
GO:0046676 negative regulation of insulin secretion 4.0541 7 yes
GO:0046888 negative regulation of hormone secretion 4.0541 5 yes
GO:0050709 negative regulation of protein secretion 4.0541 6 yes
GO:0050996 positive regulation of lipid catabolic process 4.0541 6 yes
GO:0051048 negative regulation of secretion 4.0541 5 yes
GO:0051224 negative regulation of protein transport 4.0541 5 yes
GO:0070542 response to fatty acid 4.0541 4 yes
GO:0070875 positive regulation of glycogen metabolic process 4.0541 6 yes
GO:0090278 negative regulation of peptide hormone secretion 4.0541 6 yes
GO:1903531 negative regulation of secretion by cell 4.0541 5 yes
GO:0002792 negative regulation of peptide secretion 4.0541 6 yes
GO:0010565 regulation of cellular ketone metabolic process 4.0541 5 yes
GO:0010906 regulation of glucose metabolic process 4.0541 5 yes
GO:0010907 positive regulation of glucose metabolic process 4.0541 6 yes
GO:0019217 regulation of fatty acid metabolic process 4.0541 6 yes
GO:0032000 positive regulation of fatty acid beta-oxidation 2.7027 7 yes
GO:0045923 positive regulation of fatty acid metabolic process 2.7027 6 yes
GO:0046321 positive regulation of fatty acid oxidation 2.7027 7 yes
GO:0071398 cellular response to fatty acid 2.7027 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
VIME_HUMAN [view entry] [view interactions] Low throughput yes no
PTPRF_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRA_HUMAN [view interactions] Low throughput no yes
FAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
HDAC2_HUMAN [view interactions] Low throughput no yes
PELI2_HUMAN [view interactions] Low throughput no yes
SOCS1_HUMAN [view interactions] Low throughput no yes
KHDR1_HUMAN [view interactions] Low throughput no yes
IKKA_HUMAN [view interactions] Low throughput no yes
IKKB_HUMAN [view interactions] Low throughput no yes
BCL2_HUMAN [view interactions] Low throughput no no
B2CL1_HUMAN [view interactions] Low throughput no yes
MTOR_HUMAN [view entry] [view interactions] Low throughput yes yes
RPTOR_HUMAN [view interactions] Low throughput no yes
JAK3_HUMAN [view interactions] Low throughput no no
JAK1_HUMAN [view interactions] Low throughput no yes
JAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCD_HUMAN [view entry] [view interactions] Low throughput yes yes
NISCH_HUMAN [view interactions] Low throughput no yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBF1_HUMAN [view interactions] Low throughput no yes
CBLB_HUMAN [view entry] [view interactions] Low throughput yes yes
ESR1_HUMAN [view interactions] Low throughput no no
CBL_HUMAN [view interactions] Low throughput no yes
GRB10_HUMAN [view entry] [view interactions] Low throughput yes yes
SOCS3_HUMAN [view interactions] Low throughput no yes
P85B_HUMAN [view interactions] Low throughput no yes
PK3CB_HUMAN [view interactions] Low throughput no yes
IRS2_HUMAN [view interactions] Low throughput no yes
SQSTM_HUMAN [view interactions] Low throughput no yes
DVL2_HUMAN [view interactions] Low throughput no yes
RBX1_HUMAN [view entry] [view interactions] Low throughput yes no
FBX40_HUMAN [view interactions] Low throughput no no
UBP7_HUMAN [view interactions] Low throughput no yes
PTEN_HUMAN [view entry] [view interactions] Low throughput yes yes
FBXW8_HUMAN [view interactions] Low throughput no yes
CUL7_HUMAN [view interactions] Low throughput no yes
CAV2_HUMAN [view interactions] Low throughput no no
CUL1_HUMAN [view interactions] Low throughput no yes
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
CD36_HUMAN [view interactions] Low throughput no no
SYPH_HUMAN [view entry] [view interactions] Low throughput yes yes
SH2B1_HUMAN [view interactions] Low throughput no yes
CD2AP_HUMAN [view interactions] Low throughput no no
USP9X_HUMAN [view entry] [view interactions] Low throughput yes yes
RAD51_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
MDM2_HUMAN [view entry] [view interactions] Low throughput yes yes
KLHL9_HUMAN [view interactions] Low throughput no no
KLH13_HUMAN [view interactions] Low throughput no no
CUL3_HUMAN [view entry] [view interactions] Low throughput yes yes
TRAF4_HUMAN [view interactions] Low throughput no yes
AP3S1_HUMAN [view entry] [view interactions] Low throughput yes no
NCK2_HUMAN [view entry] [view interactions] Low throughput yes yes
KS6B1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRU_HUMAN [view interactions] Low throughput no yes
SIK2_HUMAN [view interactions] Low throughput no yes
MK03_HUMAN [view entry] [view interactions] Low throughput yes yes
PASK_HUMAN [view interactions] Low throughput no yes
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
AP2M1_HUMAN [view entry] [view interactions] Low throughput yes yes
GRB2_HUMAN [view entry] [view interactions] Low throughput yes yes
P55G_HUMAN [view interactions] Low throughput no yes
1433E_HUMAN [view entry] [view interactions] Low throughput yes yes
IGF1R_HUMAN [view entry] [view interactions] Low throughput yes yes
INSR_HUMAN [view interactions] Low throughput no yes
NUCL_HUMAN [view interactions] Low throughput no yes
PHIP_HUMAN [view interactions] Low throughput no yes
ASPP2_HUMAN [view interactions] Low throughput no yes
1433B_HUMAN [view entry] [view interactions] Low throughput yes yes
P85A_HUMAN [view interactions] Low throughput no yes
KPCZ_HUMAN [view entry] [view interactions] Low throughput yes yes
SIR1_HUMAN [view interactions] Low throughput no yes
PK3CA_HUMAN [view entry] [view interactions] Low throughput yes yes
PABP1_HUMAN [view entry] [view interactions] Low throughput yes yes
1433F_HUMAN [view entry] [view interactions] Low throughput yes yes
TRI72_HUMAN [view interactions] Low throughput no no
PTN11_HUMAN [view entry] [view interactions] Low throughput yes yes
CRK_HUMAN [view entry] [view interactions] Low throughput yes no
PHB1_HUMAN [view entry] [view interactions] Low throughput yes yes
2AAA_HUMAN [view entry] [view interactions] Low throughput yes no
H10_HUMAN [view interactions] Low throughput no yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
MK08_HUMAN [view interactions] Low throughput no yes
MK09_HUMAN [view interactions] Low throughput no yes
GRB14_HUMAN [view interactions] Low throughput no yes
E2AK2_HUMAN [view entry] [view interactions] Low throughput yes yes
IF4E_HUMAN [view entry] [view interactions] Low throughput yes yes
CYH2_HUMAN [view entry] [view interactions] Low throughput yes yes
CYH3_HUMAN [view entry] [view interactions] Low throughput yes yes
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
RS27A_HUMAN [view entry] [view interactions] Low throughput yes yes
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCT_HUMAN [view interactions] Low throughput no no
IL4RA_HUMAN [view interactions] Low throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
LIPB1_HUMAN [view interactions] High throughput no yes
UNG_HUMAN [view interactions] High throughput no yes
CNOT9_HUMAN [view interactions] High throughput no yes
IPO9_HUMAN [view interactions] High throughput no no
TEN3_HUMAN [view interactions] High throughput no yes
SYRC_HUMAN [view interactions] High throughput no yes
RAB6B_HUMAN [view entry] [view interactions] High throughput yes yes
YBOX1_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
AFF3_HUMAN [view interactions] High throughput no yes
RFC3_HUMAN [view interactions] High throughput no yes
PDIP3_HUMAN [view interactions] High throughput no no
RAN_HUMAN [view entry] [view interactions] High throughput yes no
FLOT2_HUMAN [view entry] [view interactions] High throughput yes yes
IPO8_HUMAN [view interactions] High throughput no no
EPHA2_HUMAN [view interactions] High throughput no no
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
SMAD3_HUMAN [view interactions] High throughput no yes
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
PTPRD_HUMAN [view entry] [view interactions] High throughput yes no
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
RNF4_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
FBW1A_HUMAN [view interactions] High throughput no yes
FBW1B_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
KC1A_HUMAN [view interactions] High throughput no yes
CSK22_HUMAN [view entry] [view interactions] High throughput yes no
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
RN123_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
ZDH18_HUMAN [view interactions] High throughput no yes
ZDH23_HUMAN [view interactions] High throughput no no
DYR1A_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
FBX25_HUMAN [view interactions] High throughput no no
PLCG2_HUMAN [view interactions] High throughput no yes
BGAL_HUMAN [view interactions] High throughput no yes
AMRP_HUMAN [view interactions] High throughput no yes
GDIA_HUMAN [view entry] [view interactions] High throughput yes yes
DLG1_HUMAN [view entry] [view interactions] High throughput yes yes
TRI29_HUMAN [view interactions] High throughput no no
ATPF1_HUMAN [view interactions] High throughput no yes
UN13D_HUMAN [view interactions] High throughput no yes
RPR1A_HUMAN [view interactions] High throughput no yes
NIBA2_HUMAN [view interactions] High throughput no no
FAIM1_HUMAN [view interactions] High throughput no yes
LTOR3_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
CIAO1_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
ITB3_HUMAN [view entry] [view interactions] High throughput yes no
SHC1_HUMAN [view entry] [view interactions] High throughput yes yes
NUMB_HUMAN [view entry] [view interactions] High throughput yes yes
BCAR3_HUMAN [view interactions] High throughput no yes
PELI1_HUMAN [view interactions] High throughput no yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
CTND1_HUMAN [view entry] [view interactions] High throughput yes no
SND1_HUMAN [view entry] [view interactions] High throughput yes yes
CAVN2_HUMAN [view interactions] High throughput no no
RLA0_HUMAN [view entry] [view interactions] High throughput yes yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no