SHC1_HUMAN
Evidence for PS localization
Functions
Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span . Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI003687 | LIG_SH2_GRB2like | LIG | 317 | 320 | - |
| ELMI000811 | LIG_SH2_GRB2like | LIG | 349 | 352 | - |
| ELMI000812 | LIG_SH2_GRB2like | LIG | 427 | 430 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SHC1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 46.5409 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 46.5409 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 46.5409 | 4 | no |
| GO:0005524 | ATP binding | 38.3648 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 38.3648 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 38.3648 | 5 | no |
| GO:0019900 | kinase binding | 30.1887 | 4 | yes |
| GO:0019901 | protein kinase binding | 28.9308 | 5 | yes |
| GO:0003723 | RNA binding | 24.5283 | 4 | no |
| GO:0016301 | kinase activity | 22.0126 | 4 | no |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 22.0126 | 4 | no |
| GO:0004712 | protein serine/threonine/tyrosine kinase activity | 20.1258 | 4 | no |
| GO:0045309 | protein phosphorylated amino acid binding | 8.1761 | 4 | yes |
| GO:1990782 | protein tyrosine kinase binding | 8.1761 | 6 | yes |
| GO:0001784 | phosphotyrosine residue binding | 7.5472 | 5 | yes |
| GO:0046875 | ephrin receptor binding | 7.5472 | 4 | yes |
| GO:0070851 | growth factor receptor binding | 6.9182 | 4 | yes |
| GO:0030971 | receptor tyrosine kinase binding | 5.6604 | 4 | yes |
| GO:0005126 | cytokine receptor binding | 5.0314 | 4 | yes |
| GO:0030159 | signaling receptor complex adaptor activity | 5.0314 | 4 | yes |
| GO:0005159 | insulin-like growth factor receptor binding | 4.4025 | 4 | yes |
| GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity | 2.5157 | 5 | yes |
| GO:0005154 | epidermal growth factor receptor binding | 2.5157 | 5 | yes |
| GO:0005165 | neurotrophin receptor binding | 2.5157 | 5 | yes |
| GO:0005167 | neurotrophin TRK receptor binding | 2.5157 | 6 | yes |
| GO:0005168 | neurotrophin TRKA receptor binding | 2.5157 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SHC1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 67.2956 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 61.6352 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 58.4906 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 58.4906 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 57.8616 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 55.9748 | 4 | yes |
| GO:0010646 | regulation of cell communication | 53.4591 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 50.3145 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 50.3145 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 49.6855 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 47.1698 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 44.0252 | 5 | yes |
| GO:0010468 | regulation of gene expression | 43.3962 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 42.7673 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 42.1384 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 42.1384 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 41.5094 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 40.8805 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 39.6226 | 4 | yes |
| GO:0006996 | organelle organization | 37.7358 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 37.7358 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 37.1069 | 5 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 36.4780 | 5 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 36.4780 | 6 | yes |
| GO:0023056 | positive regulation of signaling | 36.4780 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 36.4780 | 6 | yes |
| GO:0010647 | positive regulation of cell communication | 35.8491 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 35.8491 | 5 | yes |
| GO:0042325 | regulation of phosphorylation | 35.8491 | 7 | yes |
| GO:0051049 | regulation of transport | 35.2201 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 33.9623 | 5 | yes |
| GO:0010941 | regulation of cell death | 33.9623 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 33.3333 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 33.3333 | 7 | yes |
| GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | yes |
| GO:0022607 | cellular component assembly | 32.0755 | 4 | no |
| GO:0008104 | protein localization | 31.4465 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 30.8176 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 30.8176 | 6 | yes |
| GO:0043085 | positive regulation of catalytic activity | 30.1887 | 4 | no |
| GO:0060341 | regulation of cellular localization | 29.5597 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 29.5597 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 29.5597 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 28.9308 | 5 | yes |
| GO:0051338 | regulation of transferase activity | 28.9308 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 28.9308 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.9308 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 28.3019 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 28.3019 | 4 | no |
| GO:0080134 | regulation of response to stress | 28.3019 | 4 | no |
| GO:0071702 | organic substance transport | 28.3019 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.3019 | 5 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 27.6730 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.0440 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 27.0440 | 5 | no |
| GO:0043549 | regulation of kinase activity | 26.4151 | 5 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 26.4151 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 26.4151 | 6 | yes |
| GO:0032880 | regulation of protein localization | 26.4151 | 5 | no |
| GO:0071705 | nitrogen compound transport | 26.4151 | 4 | no |
| GO:0036211 | protein modification process | 26.4151 | 4 | no |
| GO:0043412 | macromolecule modification | 26.4151 | 4 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 26.4151 | 4 | yes |
| GO:0010243 | response to organonitrogen compound | 25.7862 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 25.7862 | 6 | no |
| GO:0042327 | positive regulation of phosphorylation | 25.7862 | 8 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 25.7862 | 7 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 25.7862 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.7862 | 6 | yes |
| GO:0043408 | regulation of MAPK cascade | 25.1572 | 6 | yes |
| GO:0060548 | negative regulation of cell death | 25.1572 | 5 | yes |
| GO:0030334 | regulation of cell migration | 25.1572 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 25.1572 | 7 | no |
| GO:2000145 | regulation of cell motility | 25.1572 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 25.1572 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 24.5283 | 6 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 24.5283 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 24.5283 | 5 | yes |
| GO:0048585 | negative regulation of response to stimulus | 23.8994 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 23.8994 | 4 | no |
| GO:0015031 | protein transport | 23.8994 | 4 | no |
| GO:0045859 | regulation of protein kinase activity | 23.2704 | 6 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 23.2704 | 8 | no |
| GO:0010628 | positive regulation of gene expression | 23.2704 | 6 | no |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 23.2704 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.2704 | 6 | yes |
| GO:2000026 | regulation of multicellular organismal development | 22.6415 | 4 | yes |
| GO:0051347 | positive regulation of transferase activity | 22.6415 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.6415 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 22.0126 | 6 | yes |
| GO:0010648 | negative regulation of cell communication | 22.0126 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.0126 | 4 | no |
| GO:0051336 | regulation of hydrolase activity | 22.0126 | 4 | no |
| GO:0016310 | phosphorylation | 22.0126 | 5 | no |
| GO:0007010 | cytoskeleton organization | 22.0126 | 5 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 22.0126 | 5 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.0126 | 4 | yes |
| GO:0043066 | negative regulation of apoptotic process | 22.0126 | 7 | yes |
| GO:0030155 | regulation of cell adhesion | 21.3836 | 4 | no |
| GO:0051050 | positive regulation of transport | 21.3836 | 4 | no |
| GO:0030030 | cell projection organization | 21.3836 | 4 | no |
| GO:0006468 | protein phosphorylation | 21.3836 | 5 | no |
| GO:0043933 | protein-containing complex organization | 20.7547 | 4 | no |
| GO:0009894 | regulation of catabolic process | 20.7547 | 4 | no |
| GO:0002684 | positive regulation of immune system process | 20.1258 | 4 | no |
| GO:0051726 | regulation of cell cycle | 20.1258 | 4 | no |
| GO:0006886 | intracellular protein transport | 20.1258 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 20.1258 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.1258 | 6 | no |
| GO:0043410 | positive regulation of MAPK cascade | 17.6101 | 7 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 16.9811 | 6 | yes |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | 16.3522 | 7 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 15.7233 | 4 | yes |
| GO:0070848 | response to growth factor | 15.7233 | 4 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 15.0943 | 7 | yes |
| GO:0051093 | negative regulation of developmental process | 15.0943 | 4 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 15.0943 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 15.0943 | 8 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 14.4654 | 5 | yes |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 13.2075 | 8 | yes |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 11.9497 | 8 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 11.3208 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 9.4340 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 9.4340 | 6 | yes |
| GO:0038127 | ERBB signaling pathway | 9.4340 | 6 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 8.1761 | 6 | yes |
| GO:0051253 | negative regulation of RNA metabolic process | 8.1761 | 6 | yes |
| GO:0007173 | epidermal growth factor receptor signaling pathway | 8.1761 | 7 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 7.5472 | 7 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 7.5472 | 7 | yes |
| GO:1903507 | negative regulation of nucleic acid-templated transcription | 7.5472 | 8 | yes |
| GO:0045765 | regulation of angiogenesis | 6.2893 | 5 | yes |
| GO:1901342 | regulation of vasculature development | 6.2893 | 5 | yes |
| GO:0007507 | heart development | 6.2893 | 4 | yes |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 5.6604 | 5 | yes |
| GO:0008286 | insulin receptor signaling pathway | 5.0314 | 6 | yes |
| GO:0031532 | actin cytoskeleton reorganization | 5.0314 | 4 | yes |
| GO:0042742 | defense response to bacterium | 4.4025 | 4 | yes |
| GO:0061097 | regulation of protein tyrosine kinase activity | 3.1447 | 7 | yes |
| GO:0090322 | regulation of superoxide metabolic process | 2.5157 | 6 | yes |
| GO:0007176 | regulation of epidermal growth factor-activated receptor activity | 1.8868 | 4 | yes |
| GO:0071863 | regulation of cell proliferation in bone marrow | 1.2579 | 5 | yes |
| GO:0071864 | positive regulation of cell proliferation in bone marrow | 1.2579 | 6 | yes |
| GO:1901343 | negative regulation of vasculature development | 1.2579 | 5 | yes |
| GO:2000181 | negative regulation of blood vessel morphogenesis | 1.2579 | 5 | yes |
| GO:0016525 | negative regulation of angiogenesis | 1.2579 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in SHC1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 3.1447 | 3 | no |
| DOID:0050686 | organ system cancer | 2.5157 | 3 | no |
| DOID:936 | brain disease | 1.8868 | 4 | no |
| DOID:193 | reproductive organ cancer | 1.2579 | 4 | no |
| DOID:0111962 | combined immunodeficiency | 1.2579 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 1.2579 | 3 | no |
| DOID:627 | severe combined immunodeficiency | 1.2579 | 5 | no |
| DOID:6457 | Cowden syndrome | 1.2579 | 3 | no |
| DOID:0050155 | sensory system disease | 1.2579 | 3 | no |
| DOID:0050563 | nonsyndromic deafness | 1.2579 | 5 | no |
| DOID:0050564 | autosomal dominant nonsyndromic deafness | 1.2579 | 6 | no |
| DOID:2742 | auditory system disease | 1.2579 | 4 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 1.2579 | 6 | no |
| DOID:1289 | neurodegenerative disease | 1.2579 | 4 | no |
| DOID:231 | motor neuron disease | 1.2579 | 5 | no |
| DOID:440 | neuromuscular disease | 1.2579 | 5 | no |
| DOID:574 | peripheral nervous system disease | 1.2579 | 3 | no |
| DOID:870 | neuropathy | 1.2579 | 4 | no |
| DOID:120 | female reproductive organ cancer | 1.2579 | 5 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| FCG3A_HUMAN | [view interactions] | Low throughput | no | no |
| PTN12_HUMAN | [view interactions] | Low throughput | no | yes |
| KPCD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| P3C2B_HUMAN | [view interactions] | Low throughput | no | no |
| SH2B2_HUMAN | [view interactions] | Low throughput | no | no |
| SOMA_HUMAN | [view interactions] | Low throughput | no | no |
| MK14_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARHG5_HUMAN | [view interactions] | Low throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CEAM1_HUMAN | [view interactions] | Low throughput | no | no |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| LCP2_HUMAN | [view interactions] | Low throughput | no | yes |
| IL3RB_HUMAN | [view interactions] | Low throughput | no | no |
| GAB2_HUMAN | [view interactions] | Low throughput | no | yes |
| CD22_HUMAN | [view interactions] | Low throughput | no | no |
| SHIP1_HUMAN | [view interactions] | Low throughput | no | no |
| CADH5_HUMAN | [view interactions] | Low throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TIE2_HUMAN | [view interactions] | Low throughput | no | no |
| NTRK1_HUMAN | [view interactions] | Low throughput | no | yes |
| VGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| LYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RET_HUMAN | [view interactions] | Low throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ERBB3_HUMAN | [view interactions] | Low throughput | no | yes |
| ERBB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GHR_HUMAN | [view interactions] | Low throughput | no | yes |
| FCG2B_HUMAN | [view interactions] | Low throughput | no | no |
| CD3E_HUMAN | [view interactions] | Low throughput | no | no |
| GRAP2_HUMAN | [view interactions] | Low throughput | no | no |
| GRAP_HUMAN | [view interactions] | Low throughput | no | no |
| MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DDR1_HUMAN | [view interactions] | Low throughput | no | yes |
| SHC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ALK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LTK_HUMAN | [view interactions] | Low throughput | no | no |
| NTRK3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| K1C18_HUMAN | [view interactions] | Low throughput | no | no |
| FCGR1_HUMAN | [view interactions] | Low throughput | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CD3Z_HUMAN | [view interactions] | Low throughput | no | no |
| SHIP2_HUMAN | [view interactions] | Low throughput | no | yes |
| UBS3B_HUMAN | [view interactions] | Low throughput | no | yes |
| CSK_HUMAN | [view interactions] | Low throughput | no | yes |
| CRK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MET_HUMAN | [view interactions] | Low throughput | no | yes |
| STA5A_HUMAN | [view interactions] | Low throughput | no | no |
| VGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| MAPK2_HUMAN | [view interactions] | Low throughput | no | yes |
| DOK1_HUMAN | [view interactions] | Low throughput | no | yes |
| PLS1_HUMAN | [view interactions] | Low throughput | no | no |
| LRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IL4RA_HUMAN | [view interactions] | Low throughput | no | no |
| PLCG2_HUMAN | [view interactions] | Low throughput | no | yes |
| FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPHA2_HUMAN | [view interactions] | Low throughput | no | no |
| PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBLB_HUMAN | [view interactions] | Low throughput | no | yes |
| CSF3R_HUMAN | [view interactions] | Low throughput | no | yes |
| VGFR3_HUMAN | [view interactions] | Low throughput | no | yes |
| SOS2_HUMAN | [view interactions] | Low throughput | no | yes |
| IL2RG_HUMAN | [view interactions] | Low throughput | no | no |
| DAG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RHG32_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPOR_HUMAN | [view interactions] | Low throughput | no | no |
| VAV3_HUMAN | [view interactions] | Low throughput | no | yes |
| IL2RB_HUMAN | [view interactions] | Low throughput | no | no |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| TNR16_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PGFRB_HUMAN | [view interactions] | Low throughput | no | yes |
| CRKL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RPGF1_HUMAN | [view interactions] | Low throughput | no | yes |
| STA5B_HUMAN | [view interactions] | Low throughput | no | yes |
| CALD1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RON_HUMAN | [view interactions] | Low throughput | no | yes |
| IL6RB_HUMAN | [view interactions] | Low throughput | no | no |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| SOCS1_HUMAN | [view interactions] | Low throughput | no | yes |
| CSF1R_HUMAN | [view interactions] | Low throughput | no | yes |
| DDR2_HUMAN | [view interactions] | Low throughput | no | no |
| IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| INSR_HUMAN | [view interactions] | Low throughput | no | yes |
| GAB1_HUMAN | [view interactions] | Low throughput | no | yes |
| SHCBP_HUMAN | [view interactions] | Low throughput | no | no |
| HGF_HUMAN | [view interactions] | Low throughput | no | yes |
| SOCS4_HUMAN | [view interactions] | Low throughput | no | yes |
| SOCS5_HUMAN | [view interactions] | Low throughput | no | yes |
| ZAP70_HUMAN | [view interactions] | Low throughput | no | no |
| ITAV_HUMAN | [view interactions] | Low throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| AP2A2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FGFR2_HUMAN | [view interactions] | Low throughput | no | yes |
| FGFR1_HUMAN | [view interactions] | Low throughput | no | yes |
| UFO_HUMAN | [view interactions] | Low throughput | no | no |
| NTRK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHPS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTN2_HUMAN | [view interactions] | Low throughput | no | yes |
| EGF_HUMAN | [view interactions] | Low throughput | no | no |
| MLP3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AAPK1_HUMAN | [view interactions] | Low throughput | no | no |
| YES_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRB7_HUMAN | [view interactions] | Low throughput | no | no |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD3G_HUMAN | [view interactions] | High throughput | no | no |
| 2ABA_HUMAN | [view interactions] | High throughput | no | yes |
| CD3D_HUMAN | [view interactions] | High throughput | no | no |
| 2ABD_HUMAN | [view interactions] | High throughput | no | yes |
| AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| CND1_HUMAN | [view interactions] | High throughput | no | yes |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| M4K3_HUMAN | [view interactions] | High throughput | no | no |
| MTMRE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M4K5_HUMAN | [view interactions] | High throughput | no | no |
| IPO4_HUMAN | [view interactions] | High throughput | no | no |
| DD19B_HUMAN | [view interactions] | High throughput | no | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL9_HUMAN | [view interactions] | High throughput | no | no |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| PDD2L_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THB_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GARE1_HUMAN | [view interactions] | High throughput | no | yes |
| GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
| PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
| ACOT9_HUMAN | [view interactions] | High throughput | no | yes |
| CPNS1_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI15_HUMAN | [view interactions] | High throughput | no | no |
| TMED1_HUMAN | [view interactions] | High throughput | no | yes |
| CLIC4_HUMAN | [view interactions] | High throughput | no | no |
| P5CR2_HUMAN | [view interactions] | High throughput | no | yes |
| METK1_HUMAN | [view interactions] | High throughput | no | no |
| EPCR_HUMAN | [view interactions] | High throughput | no | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PP1R8_HUMAN | [view interactions] | High throughput | no | yes |
| RMD1_HUMAN | [view interactions] | High throughput | no | no |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| VP33A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITB7_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EHD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF5A1_HUMAN | [view interactions] | High throughput | no | yes |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDV3_HUMAN | [view interactions] | High throughput | no | no |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| IRS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BUB1_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| RB_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
| SERB_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC16A_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| USP9Y_HUMAN | [view interactions] | High throughput | no | no |
| PPIP2_HUMAN | [view interactions] | High throughput | no | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTA1_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERRFI_HUMAN | [view interactions] | High throughput | no | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRY3_HUMAN | [view interactions] | High throughput | no | no |
| S10A8_HUMAN | [view interactions] | High throughput | no | no |
| S10A9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD3_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| KIT_HUMAN | [view interactions] | High throughput | no | no |
| CE170_HUMAN | [view interactions] | High throughput | no | yes |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA5_HUMAN | [view interactions] | High throughput | no | no |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOK2_HUMAN | [view interactions] | High throughput | no | no |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K2C1_HUMAN | [view interactions] | High throughput | no | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C10_HUMAN | [view interactions] | High throughput | no | no |
| K1C9_HUMAN | [view interactions] | High throughput | no | no |
| K22E_HUMAN | [view interactions] | High throughput | no | no |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACACA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K2C5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K2C6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBA8_HUMAN | [view interactions] | High throughput | no | yes |
| K1C14_HUMAN | [view interactions] | High throughput | no | no |
| HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K1C16_HUMAN | [view interactions] | High throughput | no | no |
| ACTS_HUMAN | [view interactions] | High throughput | no | no |
| TBB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| K2C3_HUMAN | [view interactions] | High throughput | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBGPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH14_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| TBAL3_HUMAN | [view interactions] | High throughput | no | no |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| BCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K2C1B_HUMAN | [view interactions] | High throughput | no | yes |
| K1C13_HUMAN | [view interactions] | High throughput | no | no |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATD3B_HUMAN | [view interactions] | High throughput | no | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYVC_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAM_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEC_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRSK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| SMAP_HUMAN | [view interactions] | High throughput | no | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBLC_HUMAN | [view interactions] | High throughput | no | yes |
| S10A7_HUMAN | [view interactions] | High throughput | no | no |
| DUS23_HUMAN | [view interactions] | High throughput | no | yes |
| ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F118B_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI7_HUMAN | [view interactions] | High throughput | no | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMOX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| LG3BP_HUMAN | [view interactions] | High throughput | no | no |
| RM44_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF5_HUMAN | [view interactions] | High throughput | no | yes |
| OSGEP_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| PRKRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| SUV92_HUMAN | [view interactions] | High throughput | no | no |
| RFFL_HUMAN | [view interactions] | High throughput | no | yes |
| SHC2_HUMAN | [view interactions] | High throughput | no | yes |
| NEU1_HUMAN | [view interactions] | High throughput | no | no |
| LRRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR4_HUMAN | [view interactions] | High throughput | no | yes |
| COR2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPIP3_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| AP1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLIN3_HUMAN | [view interactions] | High throughput | no | yes |
| CBAR1_HUMAN | [view interactions] | High throughput | no | no |
| TTC23_HUMAN | [view interactions] | High throughput | no | yes |
| IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEDC2_HUMAN | [view interactions] | High throughput | no | no |
| AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRCC3_HUMAN | [view interactions] | High throughput | no | no |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT7A_HUMAN | [view interactions] | High throughput | no | yes |
| AP2S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCAR1_HUMAN | [view interactions] | Computational | no | yes |
| VEGFC_HUMAN | [view interactions] | Computational | no | no |
| VEGFD_HUMAN | [view interactions] | Computational | no | no |
| ASM_HUMAN | [view interactions] | Computational | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NTF3_HUMAN | [view interactions] | Computational | no | no |
| RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| FCERA_HUMAN | [view interactions] | Computational | no | yes |
| DRA_HUMAN | [view interactions] | Computational | no | no |
| IL2_HUMAN | [view interactions] | Computational | no | no |
| MK11_HUMAN | [view interactions] | Computational | no | yes |
| CTF1_HUMAN | [view interactions] | Computational | no | no |
| PTN1_HUMAN | [view interactions] | Computational | no | yes |
| TPOR_HUMAN | [view interactions] | Computational | no | no |
| XBP1_HUMAN | [view interactions] | Computational | no | no |
| KPCD1_HUMAN | [view interactions] | Computational | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LAMA1_HUMAN | [view interactions] | Computational | no | no |
| SDC2_HUMAN | [view interactions] | Computational | no | yes |
| VAV_HUMAN | [view interactions] | Computational | no | no |
| TFF2_HUMAN | [view interactions] | Computational | no | no |
| KPCA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HLAA_HUMAN | [view interactions] | Computational | no | no |
| NTF4_HUMAN | [view interactions] | Computational | no | no |
| FLT3_HUMAN | [view interactions] | Computational | no | no |
| GFRA1_HUMAN | [view interactions] | Computational | no | no |
| FCERB_HUMAN | [view interactions] | Computational | no | no |
| FCERG_HUMAN | [view interactions] | Computational | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CD79A_HUMAN | [view interactions] | Computational | no | no |
| KSYK_HUMAN | [view interactions] | Computational | no | no |
| S1PR1_HUMAN | [view interactions] | Computational | no | no |
| MP2K2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RACK1_HUMAN | [view interactions] | Computational | no | yes |
| EFNA1_HUMAN | [view interactions] | Computational | no | no |
| FAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RASA1_HUMAN | [view interactions] | Computational | no | yes |
| EPHB1_HUMAN | [view interactions] | Computational | no | no |
| KS6B1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FRS3_HUMAN | [view interactions] | Computational | no | no |
| BLNK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SPY2_HUMAN | [view interactions] | Computational | no | yes |
| ANGT_HUMAN | [view interactions] | Computational | no | no |
| IGF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BTK_HUMAN | [view interactions] | Computational | no | no |
| BDNF_HUMAN | [view interactions] | Computational | no | yes |
| LAT_HUMAN | [view interactions] | Computational | no | no |
| CD4_HUMAN | [view interactions] | Computational | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CSF2_HUMAN | [view interactions] | Computational | no | no |
| EFNB3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| BCL6_HUMAN | [view interactions] | Computational | no | no |
| NGF_HUMAN | [view interactions] | Computational | no | no |
| ITA6_HUMAN | [view interactions] | Computational | no | yes |
| AGTR2_HUMAN | [view interactions] | Computational | no | no |
| JAK1_HUMAN | [view interactions] | Computational | no | yes |
| NRG1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| INS_HUMAN | [view interactions] | Computational | no | no |
| CD8B_HUMAN | [view interactions] | Computational | no | no |
| ANGP1_HUMAN | [view interactions] | Computational | no | no |
| MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IL3_HUMAN | [view interactions] | Computational | no | no |
| CEGT_HUMAN | [view interactions] | Computational | no | yes |
| SMS1_HUMAN | [view interactions] | Computational | no | yes |
| GBB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CSF2R_HUMAN | [view interactions] | Computational | no | no |
| RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IRS2_HUMAN | [view interactions] | Computational | no | yes |
| CD8A_HUMAN | [view interactions] | Computational | no | no |
| LX15B_HUMAN | [view interactions] | Computational | no | no |
| LCK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| LAMB1_HUMAN | [view interactions] | Computational | no | yes |
| TFF3_HUMAN | [view interactions] | Computational | no | no |
| JAK3_HUMAN | [view interactions] | Computational | no | no |
| CAV1_HUMAN | [view interactions] | Computational | no | no |
| DRB1_HUMAN | [view interactions] | Computational | no | no |
| MK09_HUMAN | [view interactions] | Computational | no | yes |
| LIF_HUMAN | [view interactions] | Computational | no | yes |
| ITA1_HUMAN | [view interactions] | Computational | no | yes |
| TFF1_HUMAN | [view interactions] | Computational | no | no |
| PDGFA_HUMAN | [view interactions] | Computational | no | yes |
| MK08_HUMAN | [view interactions] | Computational | no | yes |
| GAB4_HUMAN | [view interactions] | Computational | no | no |
| CD79B_HUMAN | [view interactions] | Computational | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PGFRA_HUMAN | [view interactions] | Computational | no | no |
| IL4_HUMAN | [view interactions] | Computational | no | no |
| SHC3_HUMAN | [view interactions] | Computational | no | yes |
| FGR_HUMAN | [view interactions] | Computational | no | no |
| GBG1_HUMAN | [view interactions] | Computational | no | no |
| HBEGF_HUMAN | [view interactions] | Computational | no | no |
| GDNF_HUMAN | [view interactions] | Computational | no | yes |
| KPCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FGFR3_HUMAN | [view interactions] | Computational | no | yes |
| FRS2_HUMAN | [view interactions] | Computational | no | no |
| MP2K1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IKZF3_HUMAN | [view interactions] | Computational | no | no |
| PDGFB_HUMAN | [view interactions] | Computational | no | yes |
| IL2RA_HUMAN | [view interactions] | Computational | no | no |
| PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LAMC2_HUMAN | [view interactions] | Computational | no | no |
| MP2K7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GRB10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CREB1_HUMAN | [view interactions] | Computational | no | yes |
| TGFB3_HUMAN | [view interactions] | Computational | no | no |
| EFNB1_HUMAN | [view interactions] | Computational | no | yes |
| CTND1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| OSMR_HUMAN | [view interactions] | Computational | no | yes |
| EPO_HUMAN | [view interactions] | Computational | no | no |
| MTOR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IL6_HUMAN | [view interactions] | Computational | no | no |
| IL3RA_HUMAN | [view interactions] | Computational | no | yes |
| GRAB_HUMAN | [view interactions] | Computational | no | no |
| IL6RA_HUMAN | [view interactions] | Computational | no | no |
| RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |