K2C5_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in K2C5_HUMAN |
|---|---|---|---|---|
| GO:0031625 | ubiquitin protein ligase binding | 30.7692 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 30.7692 | 4 | no |
| GO:0019900 | kinase binding | 26.9231 | 4 | no |
| GO:0019901 | protein kinase binding | 26.9231 | 5 | no |
| GO:0015631 | tubulin binding | 23.0769 | 4 | no |
| GO:0003723 | RNA binding | 23.0769 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in K2C5_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 65.3846 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 61.5385 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 61.5385 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 57.6923 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 57.6923 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 57.6923 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 57.6923 | 4 | no |
| GO:0022607 | cellular component assembly | 53.8462 | 4 | no |
| GO:0006996 | organelle organization | 50.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 50.0000 | 5 | no |
| GO:0009966 | regulation of signal transduction | 50.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 50.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 46.1538 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 46.1538 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 46.1538 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 46.1538 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 46.1538 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 46.1538 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 46.1538 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 46.1538 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 42.3077 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 42.3077 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 38.4615 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 38.4615 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 38.4615 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 38.4615 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 38.4615 | 6 | no |
| GO:0033043 | regulation of organelle organization | 38.4615 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 38.4615 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 38.4615 | 5 | no |
| GO:0043933 | protein-containing complex organization | 34.6154 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 34.6154 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 34.6154 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 34.6154 | 5 | no |
| GO:0023057 | negative regulation of signaling | 34.6154 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 34.6154 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 30.7692 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 30.7692 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 30.7692 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.7692 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 30.7692 | 5 | no |
| GO:0031399 | regulation of protein modification process | 30.7692 | 6 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 26.9231 | 7 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 26.9231 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 26.9231 | 5 | no |
| GO:0071702 | organic substance transport | 26.9231 | 4 | no |
| GO:0071705 | nitrogen compound transport | 26.9231 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 26.9231 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.9231 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.9231 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.9231 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 26.9231 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 26.9231 | 5 | no |
| GO:0023056 | positive regulation of signaling | 26.9231 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.9231 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.9231 | 6 | no |
| GO:0071310 | cellular response to organic substance | 26.9231 | 4 | no |
| GO:0007010 | cytoskeleton organization | 26.9231 | 5 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 23.0769 | 4 | no |
| GO:0036211 | protein modification process | 23.0769 | 4 | no |
| GO:0043412 | macromolecule modification | 23.0769 | 4 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 23.0769 | 5 | no |
| GO:0045893 | positive regulation of DNA-templated transcription | 23.0769 | 7 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 23.0769 | 6 | no |
| GO:1902680 | positive regulation of RNA biosynthetic process | 23.0769 | 7 | no |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 23.0769 | 8 | no |
| GO:0008104 | protein localization | 23.0769 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 23.0769 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 23.0769 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.0769 | 7 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.0769 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 23.0769 | 7 | no |
| GO:0043549 | regulation of kinase activity | 23.0769 | 5 | no |
| GO:0045859 | regulation of protein kinase activity | 23.0769 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.0769 | 5 | no |
| GO:0051338 | regulation of transferase activity | 23.0769 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 23.0769 | 6 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 23.0769 | 4 | no |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 23.0769 | 5 | no |
| GO:0010941 | regulation of cell death | 23.0769 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 23.0769 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 23.0769 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 23.0769 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 23.0769 | 6 | no |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in K2C5_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 7.6923 | 3 | no |
| DOID:10534 | stomach cancer | 7.6923 | 5 | no |
| DOID:3119 | gastrointestinal system cancer | 7.6923 | 4 | no |
| DOID:37 | skin disease | 7.6923 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LOX12_HUMAN | [view interactions] | Low throughput | no | no |
| PKP2_HUMAN | [view interactions] | Low throughput | no | yes |
| K1C14_HUMAN | [view interactions] | Low throughput | no | no |
| TCHP_HUMAN | [view interactions] | Low throughput | no | yes |
| SUMO2_HUMAN | [view interactions] | Low throughput | no | yes |
| K1C18_HUMAN | [view interactions] | Low throughput | no | no |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| P63_HUMAN | [view interactions] | High throughput | no | no |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRAP_HUMAN | [view interactions] | High throughput | no | no |
| CKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| YETS4_HUMAN | [view interactions] | High throughput | no | no |
| MTA70_HUMAN | [view interactions] | High throughput | no | no |
| FL2D_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| MTM1_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| BTK_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| IGHG1_HUMAN | [view interactions] | High throughput | no | no |
| ALBU_HUMAN | [view interactions] | High throughput | no | no |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRT38_HUMAN | [view interactions] | High throughput | no | no |
| K1C15_HUMAN | [view interactions] | High throughput | no | no |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| K1C40_HUMAN | [view interactions] | High throughput | no | no |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| K1C25_HUMAN | [view interactions] | High throughput | no | no |
| K1C28_HUMAN | [view interactions] | High throughput | no | no |
| KRT35_HUMAN | [view interactions] | High throughput | no | no |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| K1C27_HUMAN | [view interactions] | High throughput | no | no |
| K1C16_HUMAN | [view interactions] | High throughput | no | no |
| K1C24_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| INCA1_HUMAN | [view interactions] | High throughput | no | no |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| DCNL1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| NEDD8_HUMAN | [view interactions] | High throughput | no | yes |
| CSN6_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view interactions] | High throughput | no | yes |
| NANOG_HUMAN | [view interactions] | High throughput | no | no |
| NANP8_HUMAN | [view interactions] | High throughput | no | no |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| UBS3B_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGN_HUMAN | [view interactions] | High throughput | no | yes |
| IF4A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHI1_HUMAN | [view interactions] | High throughput | no | yes |
| MKS1_HUMAN | [view interactions] | High throughput | no | no |
| NPHP1_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP3_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| CE290_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| CBAR1_HUMAN | [view interactions] | High throughput | no | no |
| TTC23_HUMAN | [view interactions] | High throughput | no | yes |
| TEDC2_HUMAN | [view interactions] | High throughput | no | no |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| PTMA_HUMAN | [view interactions] | High throughput | no | yes |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM45_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| RN208_HUMAN | [view interactions] | High throughput | no | no |
| INSI1_HUMAN | [view interactions] | High throughput | no | no |
| INSI2_HUMAN | [view interactions] | High throughput | no | yes |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| THB_HUMAN | [view interactions] | High throughput | no | no |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| K2C3_HUMAN | [view interactions] | High throughput | no | no |
| K1C10_HUMAN | [view interactions] | High throughput | no | no |
| K2C1_HUMAN | [view interactions] | High throughput | no | no |
| K22E_HUMAN | [view interactions] | High throughput | no | no |
| EVPL_HUMAN | [view interactions] | High throughput | no | yes |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| FAKD3_HUMAN | [view interactions] | High throughput | no | yes |
| MARH5_HUMAN | [view interactions] | High throughput | no | no |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLEC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NAPSA_HUMAN | [view interactions] | Computational | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PRGR_HUMAN | [view interactions] | Computational | no | no |