Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

FAK1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Isoform 6 (FRNK) does not contain a kinase domain and inhibits PTK2/FAK1 phosphorylation and signaling. Its enhanced expression can attenuate the nuclear accumulation of LPXN and limit its ability to enhance serum response factor (SRF)-dependent gene transcription. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI002032 DOC_WW_Pin1_4 DOC 907 912 -
ELMI000405 LIG_SH2_GRB2like LIG 925 928 -
ELMI002126 LIG_SH2_SRC LIG 397 400 -
ELMI002195 LIG_SH3_2 LIG 712 717 -
ELMI001460 MOD_ProDKin_1 MOD 907 913 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in FAK1_HUMAN
GO:0017076 purine nucleotide binding 37.1429 4 yes
GO:0032555 purine ribonucleotide binding 36.5714 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 34.2857 4 yes
GO:0019900 kinase binding 30.8571 4 yes
GO:0019901 protein kinase binding 29.7143 5 yes
GO:0046872 metal ion binding 28.0000 4 no
GO:0030554 adenyl nucleotide binding 27.4286 5 yes
GO:0032559 adenyl ribonucleotide binding 26.8571 5 yes
GO:0005524 ATP binding 24.5714 5 yes
GO:0016301 kinase activity 21.7143 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 21.7143 4 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 20.0000 4 yes
GO:0003779 actin binding 13.1429 4 yes
GO:0019902 phosphatase binding 9.7143 4 yes
GO:0004713 protein tyrosine kinase activity 8.5714 4 yes
GO:0019903 protein phosphatase binding 8.0000 5 yes
GO:0004715 non-membrane spanning protein tyrosine kinase activity 5.7143 5 yes
GO:0042169 SH2 domain binding 4.5714 4 yes
GO:0008432 JUN kinase binding 1.7143 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in FAK1_HUMAN
GO:0048522 positive regulation of cellular process 73.7143 4 yes
GO:0010646 regulation of cell communication 63.4286 4 yes
GO:0060255 regulation of macromolecule metabolic process 63.4286 4 yes
GO:0080090 regulation of primary metabolic process 62.2857 4 yes
GO:0031323 regulation of cellular metabolic process 60.5714 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 60.0000 4 yes
GO:0048523 negative regulation of cellular process 59.4286 4 yes
GO:0009966 regulation of signal transduction 56.0000 4 yes
GO:0009893 positive regulation of metabolic process 50.2857 4 yes
GO:0051128 regulation of cellular component organization 49.1429 4 yes
GO:0051246 regulation of protein metabolic process 48.5714 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 46.8571 5 yes
GO:0010468 regulation of gene expression 44.0000 5 no
GO:0031325 positive regulation of cellular metabolic process 43.4286 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 43.4286 5 yes
GO:0023056 positive regulation of signaling 40.5714 4 yes
GO:0048584 positive regulation of response to stimulus 40.5714 4 yes
GO:0010647 positive regulation of cell communication 40.0000 5 yes
GO:0010941 regulation of cell death 39.4286 4 yes
GO:1902531 regulation of intracellular signal transduction 38.8571 5 yes
GO:0031399 regulation of protein modification process 37.7143 6 yes
GO:0009889 regulation of biosynthetic process 37.1429 4 no
GO:0031326 regulation of cellular biosynthetic process 37.1429 5 no
GO:0019220 regulation of phosphate metabolic process 36.5714 6 yes
GO:0042981 regulation of apoptotic process 36.5714 6 yes
GO:0043067 regulation of programmed cell death 36.5714 5 yes
GO:0051174 regulation of phosphorus metabolic process 36.5714 5 yes
GO:0009967 positive regulation of signal transduction 36.0000 5 yes
GO:0051049 regulation of transport 36.0000 4 no
GO:0051247 positive regulation of protein metabolic process 35.4286 6 yes
GO:0006996 organelle organization 35.4286 4 no
GO:0042325 regulation of phosphorylation 34.8571 7 yes
GO:0010556 regulation of macromolecule biosynthetic process 34.8571 5 no
GO:0022607 cellular component assembly 34.2857 4 yes
GO:0009892 negative regulation of metabolic process 34.2857 4 no
GO:0071310 cellular response to organic substance 33.7143 4 no
GO:0010605 negative regulation of macromolecule metabolic process 33.1429 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 32.5714 5 no
GO:0051130 positive regulation of cellular component organization 32.5714 5 no
GO:0042127 regulation of cell population proliferation 32.0000 4 yes
GO:0030030 cell projection organization 31.4286 4 yes
GO:0043085 positive regulation of catalytic activity 31.4286 4 yes
GO:0001932 regulation of protein phosphorylation 30.8571 7 yes
GO:0033043 regulation of organelle organization 30.2857 5 yes
GO:0045595 regulation of cell differentiation 30.2857 4 yes
GO:0044087 regulation of cellular component biogenesis 29.7143 4 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 29.7143 5 no
GO:0006796 phosphate-containing compound metabolic process 29.1429 4 yes
GO:0036211 protein modification process 28.5714 4 yes
GO:0043412 macromolecule modification 28.5714 4 yes
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0120036 plasma membrane bounded cell projection organization 27.4286 5 yes
GO:0051338 regulation of transferase activity 26.8571 4 yes
GO:0051252 regulation of RNA metabolic process 26.8571 5 no
GO:0009894 regulation of catabolic process 26.2857 4 yes
GO:0060341 regulation of cellular localization 26.2857 4 no
GO:0010562 positive regulation of phosphorus metabolic process 25.7143 6 yes
GO:0030334 regulation of cell migration 25.7143 5 yes
GO:0045937 positive regulation of phosphate metabolic process 25.7143 7 yes
GO:0080134 regulation of response to stress 25.7143 4 yes
GO:2000145 regulation of cell motility 25.7143 4 yes
GO:0010243 response to organonitrogen compound 25.7143 4 no
GO:0048585 negative regulation of response to stimulus 25.7143 4 no
GO:0007167 enzyme-linked receptor protein signaling pathway 25.1429 4 yes
GO:0042327 positive regulation of phosphorylation 25.1429 8 yes
GO:1902533 positive regulation of intracellular signal transduction 25.1429 6 yes
GO:0051094 positive regulation of developmental process 25.1429 4 no
GO:0022603 regulation of anatomical structure morphogenesis 24.5714 4 yes
GO:0031401 positive regulation of protein modification process 24.5714 7 yes
GO:0051336 regulation of hydrolase activity 24.5714 4 yes
GO:0010648 negative regulation of cell communication 24.5714 5 no
GO:0023057 negative regulation of signaling 24.5714 4 no
GO:1903506 regulation of nucleic acid-templated transcription 24.5714 7 no
GO:2001141 regulation of RNA biosynthetic process 24.5714 6 no
GO:0051240 positive regulation of multicellular organismal process 24.5714 4 no
GO:0031344 regulation of cell projection organization 24.5714 5 no
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 24.0000 5 yes
GO:0008284 positive regulation of cell population proliferation 24.0000 5 yes
GO:0030155 regulation of cell adhesion 24.0000 4 yes
GO:0060548 negative regulation of cell death 24.0000 5 yes
GO:0006355 regulation of DNA-templated transcription 24.0000 6 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 24.0000 6 no
GO:0008104 protein localization 23.4286 4 no
GO:0007010 cytoskeleton organization 23.4286 5 no
GO:0032880 regulation of protein localization 23.4286 5 no
GO:0016310 phosphorylation 22.8571 5 yes
GO:0043549 regulation of kinase activity 22.8571 5 yes
GO:0051248 negative regulation of protein metabolic process 22.8571 6 no
GO:0001934 positive regulation of protein phosphorylation 22.2857 8 yes
GO:0030162 regulation of proteolysis 22.2857 6 yes
GO:0051493 regulation of cytoskeleton organization 22.2857 6 yes
GO:1901701 cellular response to oxygen-containing compound 22.2857 4 no
GO:0043066 negative regulation of apoptotic process 21.7143 7 yes
GO:0043069 negative regulation of programmed cell death 21.7143 6 yes
GO:0009968 negative regulation of signal transduction 21.7143 5 no
GO:0051050 positive regulation of transport 21.7143 4 no
GO:0006468 protein phosphorylation 21.1429 5 yes
GO:0009891 positive regulation of biosynthetic process 21.1429 5 no
GO:0031328 positive regulation of cellular biosynthetic process 21.1429 6 no
GO:0010628 positive regulation of gene expression 21.1429 6 no
GO:0030335 positive regulation of cell migration 20.5714 6 yes
GO:0031329 regulation of cellular catabolic process 20.5714 5 yes
GO:0040017 positive regulation of locomotion 20.5714 4 yes
GO:2000147 positive regulation of cell motility 20.5714 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 20.5714 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 20.5714 6 no
GO:0032101 regulation of response to external stimulus 20.0000 4 yes
GO:0045859 regulation of protein kinase activity 20.0000 6 yes
GO:0018193 peptidyl-amino acid modification 19.4286 5 yes
GO:0043933 protein-containing complex organization 19.4286 4 yes
GO:0002684 positive regulation of immune system process 18.8571 4 yes
GO:0051347 positive regulation of transferase activity 17.7143 5 yes
GO:0031175 neuron projection development 17.1429 6 yes
GO:0050776 regulation of immune response 17.1429 4 yes
GO:0065003 protein-containing complex assembly 17.1429 5 yes
GO:0045862 positive regulation of proteolysis 15.4286 7 yes
GO:0010810 regulation of cell-substrate adhesion 14.8571 5 yes
GO:0033674 positive regulation of kinase activity 14.8571 6 yes
GO:0009896 positive regulation of catabolic process 14.2857 5 yes
GO:0022604 regulation of cell morphogenesis 13.7143 5 yes
GO:0032103 positive regulation of response to external stimulus 12.0000 5 yes
GO:0031331 positive regulation of cellular catabolic process 11.4286 6 yes
GO:0046777 protein autophosphorylation 11.4286 6 yes
GO:0050778 positive regulation of immune response 11.4286 5 yes
GO:0045860 positive regulation of protein kinase activity 10.8571 7 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 10.2857 4 yes
GO:0022407 regulation of cell-cell adhesion 10.2857 5 yes
GO:0043087 regulation of GTPase activity 10.2857 5 yes
GO:1903050 regulation of proteolysis involved in protein catabolic process 10.2857 7 yes
GO:0002429 immune response-activating cell surface receptor signaling pathway 9.7143 4 yes
GO:0007229 integrin-mediated signaling pathway 9.7143 4 yes
GO:0010632 regulation of epithelial cell migration 9.7143 4 yes
GO:1901888 regulation of cell junction assembly 9.7143 5 yes
GO:0001952 regulation of cell-matrix adhesion 9.1429 6 yes
GO:0007411 axon guidance 9.1429 8 yes
GO:0097485 neuron projection guidance 9.1429 7 yes
GO:0019216 regulation of lipid metabolic process 8.5714 5 yes
GO:0038127 ERBB signaling pathway 8.5714 6 yes
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 8.5714 6 yes
GO:0048013 ephrin receptor signaling pathway 8.0000 6 yes
GO:0002685 regulation of leukocyte migration 7.4286 4 yes
GO:0007173 epidermal growth factor receptor signaling pathway 7.4286 7 yes
GO:0010769 regulation of cell morphogenesis involved in differentiation 7.4286 6 yes
GO:0018108 peptidyl-tyrosine phosphorylation 7.4286 6 yes
GO:0018212 peptidyl-tyrosine modification 7.4286 6 yes
GO:0045834 positive regulation of lipid metabolic process 7.4286 5 yes
GO:0051896 regulation of protein kinase B signaling 7.4286 6 yes
GO:0007162 negative regulation of cell adhesion 6.8571 5 yes
GO:0008360 regulation of cell shape 6.8571 6 yes
GO:0010594 regulation of endothelial cell migration 6.8571 5 yes
GO:0070663 regulation of leukocyte proliferation 6.8571 5 yes
GO:0071675 regulation of mononuclear cell migration 6.8571 5 yes
GO:1903052 positive regulation of proteolysis involved in protein catabolic process 6.8571 8 yes
GO:0038093 Fc receptor signaling pathway 6.2857 5 yes
GO:0051893 regulation of focal adhesion assembly 6.2857 7 yes
GO:0090109 regulation of cell-substrate junction assembly 6.2857 6 yes
GO:0150116 regulation of cell-substrate junction organization 6.2857 5 yes
GO:1900024 regulation of substrate adhesion-dependent cell spreading 6.2857 6 yes
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 6.2857 7 yes
GO:0043550 regulation of lipid kinase activity 5.7143 6 yes
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 5.7143 7 yes
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 5.7143 7 yes
GO:0090218 positive regulation of lipid kinase activity 5.7143 6 yes
GO:0002431 Fc receptor mediated stimulatory signaling pathway 5.1429 5 yes
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 5.1429 6 yes
GO:0038094 Fc-gamma receptor signaling pathway 5.1429 6 yes
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 5.1429 4 yes
GO:0050920 regulation of chemotaxis 5.1429 4 yes
GO:0051897 positive regulation of protein kinase B signaling 5.1429 7 yes
GO:1903034 regulation of response to wounding 5.1429 5 yes
GO:0002687 positive regulation of leukocyte migration 4.5714 5 yes
GO:0002688 regulation of leukocyte chemotaxis 4.5714 5 yes
GO:0048010 vascular endothelial growth factor receptor signaling pathway 4.5714 6 yes
GO:0050921 positive regulation of chemotaxis 4.5714 5 yes
GO:0070665 positive regulation of leukocyte proliferation 4.5714 6 yes
GO:0002690 positive regulation of leukocyte chemotaxis 4.0000 6 yes
GO:0010762 regulation of fibroblast migration 4.0000 6 yes
GO:0061041 regulation of wound healing 4.0000 6 yes
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 3.4286 5 yes
GO:0010763 positive regulation of fibroblast migration 3.4286 7 yes
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 3.4286 7 yes
GO:0022408 negative regulation of cell-cell adhesion 3.4286 6 yes
GO:0033628 regulation of cell adhesion mediated by integrin 3.4286 5 yes
GO:0035994 response to muscle stretch 3.4286 4 yes
GO:2000209 regulation of anoikis 3.4286 7 yes
GO:2000811 negative regulation of anoikis 3.4286 8 yes
GO:0007172 signal complex assembly 2.8571 5 yes
GO:0007179 transforming growth factor beta receptor signaling pathway 2.8571 6 yes
GO:0010758 regulation of macrophage chemotaxis 2.8571 6 yes
GO:0060396 growth hormone receptor signaling pathway 2.8571 6 yes
GO:0071622 regulation of granulocyte chemotaxis 2.8571 6 yes
GO:1903036 positive regulation of response to wounding 2.8571 5 yes
GO:1905521 regulation of macrophage migration 2.8571 5 yes
GO:0010759 positive regulation of macrophage chemotaxis 2.2857 6 yes
GO:0045667 regulation of osteoblast differentiation 2.2857 5 yes
GO:0050982 detection of mechanical stimulus 2.2857 4 yes
GO:0090303 positive regulation of wound healing 2.2857 6 yes
GO:0120040 regulation of macrophage proliferation 2.2857 6 yes
GO:0120041 positive regulation of macrophage proliferation 2.2857 7 yes
GO:1905523 positive regulation of macrophage migration 2.2857 6 yes
GO:0001890 placenta development 1.7143 4 yes
GO:0035995 detection of muscle stretch 1.7143 5 yes
GO:0003007 heart morphogenesis 1.1429 4 yes
GO:0038007 netrin-activated signaling pathway 1.1429 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in FAK1_HUMAN
DOID:0050686 organ system cancer 4.0000 3 no
DOID:331 central nervous system disease 1.7143 3 no
DOID:0060038 specific developmental disorder 1.7143 3 no
DOID:1059 intellectual disability 1.7143 4 no
DOID:612 primary immunodeficiency disease 1.7143 3 no
DOID:193 reproductive organ cancer 1.7143 4 no
DOID:0080000 muscular disease 1.7143 3 no
DOID:423 myopathy 1.7143 5 no
DOID:66 muscle tissue disease 1.7143 4 no
DOID:936 brain disease 1.1429 4 no
DOID:0060307 autosomal dominant intellectual developmental disorder 1.1429 5 no
DOID:0050700 cardiomyopathy 1.1429 4 no
DOID:0060036 intrinsic cardiomyopathy 1.1429 5 no
DOID:114 heart disease 1.1429 3 no
DOID:12930 dilated cardiomyopathy 1.1429 6 no
DOID:10534 stomach cancer 1.1429 5 no
DOID:120 female reproductive organ cancer 1.1429 5 no
DOID:3119 gastrointestinal system cancer 1.1429 4 no
DOID:3635 congenital myasthenic syndrome 1.1429 7 no
DOID:439 neuromuscular junction disease 1.1429 6 no
DOID:440 neuromuscular disease 1.1429 5 no
DOID:574 peripheral nervous system disease 1.1429 3 no
DOID:870 neuropathy 1.1429 4 no
DOID:6457 Cowden syndrome 1.1429 3 no
DOID:9884 muscular dystrophy 1.1429 6 no
DOID:10283 prostate cancer 1.1429 6 no
DOID:3856 male reproductive organ cancer 1.1429 5 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SHC1_HUMAN [view entry] [view interactions] Low throughput yes yes
CCR5_HUMAN [view interactions] Low throughput no no
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
CXCR4_HUMAN [view interactions] Low throughput no no
BMX_HUMAN [view interactions] Low throughput no no
PKD1_HUMAN [view interactions] Low throughput no yes
TSC2_HUMAN [view entry] [view interactions] Low throughput yes yes
TSC1_HUMAN [view entry] [view interactions] Low throughput yes yes
IGF1R_HUMAN [view entry] [view interactions] Low throughput yes yes
ITA4_HUMAN [view interactions] Low throughput no no
FGR_HUMAN [view interactions] Low throughput no no
TLN1_HUMAN [view entry] [view interactions] Low throughput yes no
GELS_HUMAN [view entry] [view interactions] Low throughput yes no
AMPH_HUMAN [view entry] [view interactions] Low throughput yes yes
BIN1_HUMAN [view entry] [view interactions] Low throughput yes yes
KSYK_HUMAN [view interactions] Low throughput no no
ITB3_HUMAN [view entry] [view interactions] Low throughput yes no
P85A_HUMAN [view interactions] Low throughput no yes
RBCC1_HUMAN [view interactions] Low throughput no no
NCK1_HUMAN [view interactions] Low throughput no yes
NCK2_HUMAN [view entry] [view interactions] Low throughput yes yes
CSK_HUMAN [view interactions] Low throughput no yes
ITB1_HUMAN [view entry] [view interactions] Low throughput yes no
CBL_HUMAN [view interactions] Low throughput no yes
SRC8_HUMAN [view entry] [view interactions] Low throughput yes yes
ASAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
STAP2_HUMAN [view interactions] Low throughput no yes
CHIP_HUMAN [view entry] [view interactions] Low throughput yes yes
RBNS5_HUMAN [view interactions] Low throughput no yes
TRI72_HUMAN [view interactions] Low throughput no no
UBE2H_HUMAN [view interactions] Low throughput no yes
GBB1_HUMAN [view entry] [view interactions] Low throughput yes yes
GBG2_HUMAN [view entry] [view interactions] Low throughput yes yes
CADH5_HUMAN [view interactions] Low throughput no yes
NMDE1_HUMAN [view entry] [view interactions] Low throughput yes yes
NMDE2_HUMAN [view entry] [view interactions] Low throughput yes no
NMDZ1_HUMAN [view entry] [view interactions] Low throughput yes yes
MERL_HUMAN [view interactions] Low throughput no yes
CBLB_HUMAN [view interactions] Low throughput no yes
CD4_HUMAN [view interactions] Low throughput no no
SOCS1_HUMAN [view interactions] Low throughput no yes
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
ELOB_HUMAN [view interactions] Low throughput no no
DYN1_HUMAN [view entry] [view interactions] Low throughput yes yes
NEP_HUMAN [view interactions] Low throughput no no
XIAP_HUMAN [view interactions] Low throughput no yes
PBIP1_HUMAN [view entry] [view interactions] Low throughput yes no
MK08_HUMAN [view interactions] Low throughput no yes
TRAF2_HUMAN [view interactions] Low throughput no yes
TBK1_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCI_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
TMG4_HUMAN [view interactions] Low throughput no yes
SKP2_HUMAN [view interactions] Low throughput no yes
MISP_HUMAN [view interactions] Low throughput no no
EZRI_HUMAN [view entry] [view interactions] Low throughput yes no
RHG26_HUMAN [view entry] [view interactions] Low throughput yes yes
MDM2_HUMAN [view interactions] Low throughput no yes
DMD_HUMAN [view entry] [view interactions] Low throughput yes no
GATA4_HUMAN [view interactions] Low throughput no no
LYAM2_HUMAN [view interactions] Low throughput no no
ZFY21_HUMAN [view interactions] Low throughput no yes
G3P_HUMAN [view entry] [view interactions] Low throughput yes yes
PARP1_HUMAN [view entry] [view interactions] Low throughput yes yes
TGFI1_HUMAN [view interactions] Low throughput no no
NEO1_HUMAN [view entry] [view interactions] Low throughput yes yes
YES_HUMAN [view entry] [view interactions] Low throughput yes yes
BCAR1_HUMAN [view interactions] Low throughput no yes
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
GRB2_HUMAN [view entry] [view interactions] Low throughput yes yes
LPXN_HUMAN [view interactions] Low throughput no yes
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
RHOU_HUMAN [view interactions] Low throughput no no
PAXI_HUMAN [view interactions] Low throughput no yes
FAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
ITB4_HUMAN [view entry] [view interactions] Low throughput yes yes
TENS3_HUMAN [view interactions] Low throughput no no
LYN_HUMAN [view entry] [view interactions] Low throughput yes no
ERBB2_HUMAN [view entry] [view interactions] Low throughput yes no
PP1B_HUMAN [view entry] [view interactions] Low throughput yes yes
P53_HUMAN [view interactions] Low throughput no no
SRBS1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTN23_HUMAN [view entry] [view interactions] Low throughput yes yes
DYN2_HUMAN [view entry] [view interactions] Low throughput yes yes
CD36_HUMAN [view interactions] Low throughput no no
CADM1_HUMAN [view entry] [view interactions] Low throughput yes no
MEF2C_HUMAN [view interactions] Low throughput no yes
EGFR_HUMAN [view interactions] Low throughput no no
EPHB2_HUMAN [view entry] [view interactions] Low throughput yes yes
ELAV1_HUMAN [view entry] [view interactions] Low throughput yes yes
NRP1_HUMAN [view entry] [view interactions] Low throughput yes yes
L1CAM_HUMAN [view entry] [view interactions] Low throughput yes yes
PTN11_HUMAN [view entry] [view interactions] Low throughput yes yes
DCC_HUMAN [view entry] [view interactions] Low throughput yes yes
ANGL4_HUMAN [view interactions] Low throughput no no
EPHA2_HUMAN [view interactions] Low throughput no no
CRK_HUMAN [view entry] [view interactions] Low throughput yes no
PTH2_HUMAN [view interactions] Low throughput no yes
PK3CA_HUMAN [view entry] [view interactions] Low throughput yes yes
ARP3_HUMAN [view entry] [view interactions] Low throughput yes yes
WASL_HUMAN [view entry] [view interactions] Low throughput yes yes
OCLN_HUMAN [view interactions] Low throughput no no
STAT1_HUMAN [view entry] [view interactions] Low throughput yes no
PTAFR_HUMAN [view interactions] Low throughput no yes
PI51C_HUMAN [view entry] [view interactions] Low throughput yes yes
GRB7_HUMAN [view interactions] Low throughput no no
PTN1_HUMAN [view interactions] Low throughput no yes
STAT3_HUMAN [view entry] [view interactions] Low throughput yes yes
ITAV_HUMAN [view interactions] Low throughput no yes
PTEN_HUMAN [view entry] [view interactions] Low throughput yes yes
PLCG1_HUMAN [view entry] [view interactions] Low throughput yes yes
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
CASL_HUMAN [view interactions] Low throughput no yes
EFS_HUMAN [view interactions] Low throughput no no
SOCS3_HUMAN [view interactions] Low throughput no yes
TRIP6_HUMAN [view interactions] Low throughput no yes
BCL2_HUMAN [view interactions] Low throughput no no
CIB1_HUMAN [view interactions] Low throughput no no
GIT1_HUMAN [view entry] [view interactions] Low throughput yes yes
ITB5_HUMAN [view interactions] Low throughput no yes
JIP3_HUMAN [view entry] [view interactions] Low throughput yes yes
JAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
DAG1_HUMAN [view entry] [view interactions] High throughput yes no
SH3K1_HUMAN [view entry] [view interactions] High throughput yes yes
PDC6I_HUMAN [view entry] [view interactions] High throughput yes yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
NTRK1_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
KGP1_HUMAN [view interactions] High throughput no yes
AGAP2_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
DDX58_HUMAN [view interactions] High throughput no yes
SMAD4_HUMAN [view interactions] High throughput no yes
SWP70_HUMAN [view interactions] High throughput no no
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
MAGA9_HUMAN [view interactions] High throughput no no
PIP_HUMAN [view interactions] High throughput no no
TGM1_HUMAN [view interactions] High throughput no no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
BSPRY_HUMAN [view interactions] High throughput no no
MND1_HUMAN [view interactions] High throughput no no
PLCC_HUMAN [view interactions] High throughput no no
GLYC_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
CSK22_HUMAN [view entry] [view interactions] High throughput yes no
FKBP5_HUMAN [view interactions] High throughput no yes
RBM25_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
TIE2_HUMAN [view interactions] High throughput no no
AKT1_HUMAN [view entry] [view interactions] High throughput yes yes
TRI15_HUMAN [view interactions] High throughput no no
OTU6B_HUMAN [view interactions] High throughput no yes
TRM6_HUMAN [view interactions] High throughput no yes
MICA1_HUMAN [view interactions] High throughput no yes
ACTN1_HUMAN [view entry] [view interactions] High throughput yes yes
ZIK1_HUMAN [view interactions] High throughput no no
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
MIDN_HUMAN [view interactions] High throughput no no
NEC1_HUMAN [view interactions] High throughput no yes
NUP62_HUMAN [view interactions] High throughput no yes
NCAM1_HUMAN [view entry] [view interactions] High throughput yes no
PLCH2_HUMAN [view interactions] High throughput no yes
FAK2_HUMAN [view entry] [view interactions] High throughput yes yes
VINC_HUMAN [view entry] [view interactions] High throughput yes no
GOGA3_HUMAN [view interactions] High throughput no yes
EBP_HUMAN [view interactions] High throughput no no
DHX29_HUMAN [view interactions] High throughput no yes
ANKH1_HUMAN [view interactions] High throughput no yes
CCD13_HUMAN [view interactions] High throughput no no
ANR26_HUMAN [view interactions] High throughput no yes
LZIC_HUMAN [view interactions] High throughput no no
KCC2D_HUMAN [view entry] [view interactions] High throughput yes yes
CCD18_HUMAN [view interactions] High throughput no yes
S1PBP_HUMAN [view interactions] High throughput no yes
CDC37_HUMAN [view interactions] High throughput no yes
QRIC2_HUMAN [view interactions] High throughput no no
CP131_HUMAN [view interactions] High throughput no no
CIP2A_HUMAN [view interactions] High throughput no yes
ERAL1_HUMAN [view interactions] High throughput no yes
F193A_HUMAN [view interactions] High throughput no yes
GTPB1_HUMAN [view interactions] High throughput no yes
BBS10_HUMAN [view interactions] High throughput no no
HACL2_HUMAN [view interactions] High throughput no yes
DX39A_HUMAN [view interactions] High throughput no yes
PAPD1_HUMAN [view interactions] High throughput no yes
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
ES8L2_HUMAN [view interactions] High throughput no yes
NUDC3_HUMAN [view interactions] High throughput no yes
F13A_HUMAN [view interactions] High throughput no no
RL34_HUMAN [view entry] [view interactions] High throughput yes yes
F16P1_HUMAN [view interactions] High throughput no no
SPS2L_HUMAN [view interactions] High throughput no yes
HES1_HUMAN [view interactions] High throughput no no
WDR83_HUMAN [view interactions] High throughput no yes
ALMS1_HUMAN [view interactions] High throughput no no
NACAD_HUMAN [view interactions] High throughput no yes
AP3M1_HUMAN [view interactions] High throughput no yes
NASP_HUMAN [view interactions] High throughput no yes
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
ZN331_HUMAN [view interactions] High throughput no no
CE152_HUMAN [view interactions] High throughput no yes
SYIC_HUMAN [view interactions] High throughput no yes
IFT74_HUMAN [view interactions] High throughput no yes
KTN1_HUMAN [view entry] [view interactions] High throughput yes yes
M4K4_HUMAN [view interactions] High throughput no yes
VPS16_HUMAN [view entry] [view interactions] High throughput yes yes
MAST4_HUMAN [view interactions] High throughput no no
DCTN5_HUMAN [view interactions] High throughput no yes
OFD1_HUMAN [view interactions] High throughput no yes
PTN12_HUMAN [view interactions] High throughput no yes
PAI2_HUMAN [view interactions] High throughput no no
RL10_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RL14_HUMAN [view entry] [view interactions] High throughput yes yes
RL18A_HUMAN [view entry] [view interactions] High throughput yes yes
RL28_HUMAN [view entry] [view interactions] High throughput yes yes
RL5_HUMAN [view entry] [view interactions] High throughput yes yes
ANXA2_HUMAN [view entry] [view interactions] High throughput yes no
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
DIC_HUMAN [view interactions] High throughput no yes
SMD1_HUMAN [view interactions] High throughput no yes
TCHP_HUMAN [view interactions] High throughput no yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
SOS1_HUMAN [view entry] [view interactions] High throughput yes yes
THMS1_HUMAN [view interactions] High throughput no no
LCP2_HUMAN [view interactions] High throughput no yes
GRAP_HUMAN [view interactions] High throughput no no
GRAP2_HUMAN [view interactions] High throughput no no
CDK5_HUMAN [view entry] [view interactions] High throughput yes yes
RFC1_HUMAN [view interactions] High throughput no yes
RFC4_HUMAN [view interactions] High throughput no yes
UTP18_HUMAN [view interactions] High throughput no yes
EXOS1_HUMAN [view interactions] High throughput no yes
SRRM2_HUMAN [view interactions] High throughput no yes
DDX43_HUMAN [view interactions] High throughput no no
RBM28_HUMAN [view interactions] High throughput no yes
SSF1_HUMAN [view interactions] High throughput no yes
E41L5_HUMAN [view interactions] High throughput no no
CH033_HUMAN [view interactions] High throughput no yes
DDX24_HUMAN [view interactions] High throughput no yes
GTPB4_HUMAN [view interactions] High throughput no yes
CG050_HUMAN [view interactions] High throughput no yes
SRPK1_HUMAN [view interactions] High throughput no yes
EXOS8_HUMAN [view interactions] High throughput no yes
DHX30_HUMAN [view entry] [view interactions] High throughput yes yes
RL7L_HUMAN [view interactions] High throughput no no
DCAF8_HUMAN [view interactions] High throughput no yes
TSR1_HUMAN [view interactions] High throughput no no
NOLC1_HUMAN [view interactions] High throughput no yes
BOP1_HUMAN [view interactions] High throughput no yes
EXOS2_HUMAN [view interactions] High throughput no yes
TCOF_HUMAN [view interactions] High throughput no yes
EXOSX_HUMAN [view interactions] High throughput no yes
PURA_HUMAN [view entry] [view interactions] High throughput yes no
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
RRP1_HUMAN [view interactions] High throughput no yes
SRP09_HUMAN [view interactions] High throughput no no
FNTA_HUMAN [view interactions] High throughput no yes
RBM34_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
P4HA1_HUMAN [view interactions] High throughput no yes
SURF6_HUMAN [view interactions] High throughput no yes
CCNA1_HUMAN [view interactions] High throughput no no
DVLP1_HUMAN [view interactions] High throughput no no
DVL1_HUMAN [view entry] [view interactions] High throughput yes yes
MAL_HUMAN [view interactions] High throughput no no
P85B_HUMAN [view interactions] High throughput no yes
P55G_HUMAN [view interactions] High throughput no yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP1_HUMAN [view entry] [view interactions] High throughput yes no
HDAC4_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
SAE1_HUMAN [view entry] [view interactions] High throughput yes yes
SH21A_HUMAN [view interactions] High throughput no no
DOK4_HUMAN [view interactions] High throughput no yes
SH22A_HUMAN [view interactions] High throughput no no
SH21B_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
PIAS1_HUMAN [view interactions] High throughput no yes
RET_HUMAN [view interactions] High throughput no yes
APC_HUMAN [view entry] [view interactions] High throughput yes no
CRKL_HUMAN [view entry] [view interactions] High throughput yes yes
VGFR1_HUMAN [view interactions] High throughput no no
SOCS2_HUMAN [view interactions] High throughput no yes
ATG12_HUMAN [view interactions] High throughput no yes
DEFI6_HUMAN [view interactions] High throughput no no
PTN6_HUMAN [view interactions] High throughput no no
HCK_HUMAN [view entry] [view interactions] High throughput yes no
LCK_HUMAN [view entry] [view interactions] High throughput yes no
DOCK1_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] Computational no no
GNAI2_HUMAN [view entry] [view interactions] Computational yes yes
SDC4_HUMAN [view interactions] Computational no yes
ITA3_HUMAN [view entry] [view interactions] Computational yes yes
MK01_HUMAN [view entry] [view interactions] Computational yes yes
RAPSN_HUMAN [view entry] [view interactions] Computational yes no
ARHG7_HUMAN [view entry] [view interactions] Computational yes yes
PECA1_HUMAN [view interactions] Computational no no
RACK1_HUMAN [view interactions] Computational no yes
EFNA1_HUMAN [view interactions] Computational no no
WIPF1_HUMAN [view interactions] Computational no no
ROCK1_HUMAN [view entry] [view interactions] Computational yes yes
RAP1B_HUMAN [view entry] [view interactions] Computational yes no
ELMO1_HUMAN [view interactions] Computational no no
SHPS1_HUMAN [view entry] [view interactions] Computational yes yes
PGFRB_HUMAN [view interactions] Computational no yes
UTRN_HUMAN [view entry] [view interactions] Computational yes yes
ROCK2_HUMAN [view entry] [view interactions] Computational yes yes
ZYX_HUMAN [view interactions] Computational no no
PGFRA_HUMAN [view interactions] Computational no no
ITA7_HUMAN [view interactions] Computational no yes
ACTN2_HUMAN [view entry] [view interactions] Computational yes yes
KAP1_HUMAN [view entry] [view interactions] Computational yes yes
GNAZ_HUMAN [view entry] [view interactions] Computational yes yes
EGF_HUMAN [view interactions] Computational no no
PTN21_HUMAN [view interactions] Computational no yes
PK3CG_HUMAN [view interactions] Computational no yes
NECT3_HUMAN [view entry] [view interactions] Computational yes yes
ITA10_HUMAN [view interactions] Computational no no
KAPCB_HUMAN [view entry] [view interactions] Computational yes yes
SPN90_HUMAN [view entry] [view interactions] Computational yes no
ACM1_HUMAN [view entry] [view interactions] Computational yes yes
MK03_HUMAN [view entry] [view interactions] Computational yes yes
ACHB_HUMAN [view entry] [view interactions] Computational yes yes
WIPF3_HUMAN [view interactions] Computational no yes
RASH_HUMAN [view entry] [view interactions] Computational yes no
VAV3_HUMAN [view interactions] Computational no yes
UNC5C_HUMAN [view interactions] Computational no no
LPAR3_HUMAN [view interactions] Computational no no
RRAS_HUMAN [view interactions] Computational no yes
EFNB1_HUMAN [view interactions] Computational no yes
CASP6_HUMAN [view interactions] Computational no no
ARG28_HUMAN [view interactions] Computational no yes
LAMA5_HUMAN [view entry] [view interactions] Computational yes no
ACTS_HUMAN [view interactions] Computational no no
ITB8_HUMAN [view interactions] Computational no no
GDNF_HUMAN [view interactions] Computational no yes
KAP2_HUMAN [view entry] [view interactions] Computational yes yes
ITA5_HUMAN [view entry] [view interactions] Computational yes no
SHC3_HUMAN [view interactions] Computational no yes
SH3G1_HUMAN [view entry] [view interactions] Computational yes no
NECT1_HUMAN [view interactions] Computational no yes
GFRA1_HUMAN [view interactions] Computational no no
FCERB_HUMAN [view interactions] Computational no no
KPCA_HUMAN [view entry] [view interactions] Computational yes yes
LPAR2_HUMAN [view interactions] Computational no yes
FINC_HUMAN [view interactions] Computational no yes
MUSK_HUMAN [view entry] [view interactions] Computational yes no
VAV_HUMAN [view interactions] Computational no no
LAMA1_HUMAN [view interactions] Computational no no
MK11_HUMAN [view interactions] Computational no yes
VGFR3_HUMAN [view interactions] Computational no yes
GIT2_HUMAN [view interactions] Computational no yes
ITA2_HUMAN [view interactions] Computational no yes
SHC4_HUMAN [view entry] [view interactions] Computational yes no
PAK4_HUMAN [view interactions] Computational no yes
KAP0_HUMAN [view entry] [view interactions] Computational yes yes
RASK_HUMAN [view entry] [view interactions] Computational yes no
ITB2_HUMAN [view interactions] Computational no no
PK3CD_HUMAN [view interactions] Computational no no
LAMA2_HUMAN [view interactions] Computational no no
CASP3_HUMAN [view interactions] Computational no yes
GPER1_HUMAN [view entry] [view interactions] Computational yes yes
RGRF1_HUMAN [view interactions] Computational no yes
LAMA3_HUMAN [view interactions] Computational no no
NET1_HUMAN [view interactions] Computational no no
SPTN1_HUMAN [view entry] [view interactions] Computational yes yes
CD47_HUMAN [view interactions] Computational no no
ITB6_HUMAN [view interactions] Computational no no
CAN1_HUMAN [view entry] [view interactions] Computational yes yes
LAMB3_HUMAN [view interactions] Computational no yes
KPCG_HUMAN [view entry] [view interactions] Computational yes yes
ACHA_HUMAN [view entry] [view interactions] Computational yes no
ITA9_HUMAN [view interactions] Computational no no
LAMC1_HUMAN [view interactions] Computational no yes
KS6B1_HUMAN [view entry] [view interactions] Computational yes yes
UNC5D_HUMAN [view interactions] Computational no no
EPHB1_HUMAN [view interactions] Computational no no
RASA1_HUMAN [view interactions] Computational no yes
ICAL_HUMAN [view interactions] Computational no yes
MLC1_HUMAN [view interactions] Computational no no
MYLK_HUMAN [view interactions] Computational no no
AFAD_HUMAN [view interactions] Computational no yes
PI3R5_HUMAN [view interactions] Computational no no
PAK2_HUMAN [view entry] [view interactions] Computational yes no
RPGF1_HUMAN [view interactions] Computational no yes
PAK3_HUMAN [view entry] [view interactions] Computational yes no
TENS1_HUMAN [view interactions] Computational no no
ITA1_HUMAN [view interactions] Computational no yes
ITA8_HUMAN [view entry] [view interactions] Computational yes no
MK12_HUMAN [view interactions] Computational no no
LAMB1_HUMAN [view interactions] Computational no yes
CAN2_HUMAN [view interactions] Computational no no
AGRIN_HUMAN [view entry] [view interactions] Computational yes yes
ARHG2_HUMAN [view entry] [view interactions] Computational yes yes
SDF1_HUMAN [view interactions] Computational no no
ITA11_HUMAN [view interactions] Computational no yes
RHOA_HUMAN [view entry] [view interactions] Computational yes yes
ITB7_HUMAN [view interactions] Computational no no
KAP3_HUMAN [view entry] [view interactions] Computational yes yes
MK13_HUMAN [view interactions] Computational no yes
HCLS1_HUMAN [view interactions] Computational no no
ACTN4_HUMAN [view entry] [view interactions] Computational yes yes
JAM1_HUMAN [view interactions] Computational no yes
VAV2_HUMAN [view entry] [view interactions] Computational yes yes
PTN13_HUMAN [view interactions] Computational no yes
KAPCA_HUMAN [view entry] [view interactions] Computational yes yes
ARHG6_HUMAN [view interactions] Computational no no
LAMC2_HUMAN [view interactions] Computational no no
UNC5A_HUMAN [view interactions] Computational no no
PAK5_HUMAN [view interactions] Computational no yes
LAMB2_HUMAN [view interactions] Computational no yes
KAPCG_HUMAN [view interactions] Computational no no
PAK1_HUMAN [view entry] [view interactions] Computational yes yes
MK14_HUMAN [view interactions] Computational no yes
FCERG_HUMAN [view interactions] Computational no no
EDIL3_HUMAN [view interactions] Computational no yes
ITA2B_HUMAN [view interactions] Computational no no
GNAI1_HUMAN [view entry] [view interactions] Computational yes yes
UNC5B_HUMAN [view interactions] Computational no yes
VTNC_HUMAN [view interactions] Computational no no
LAMC3_HUMAN [view interactions] Computational no no
CPNS1_HUMAN [view interactions] Computational no yes
RGS1_HUMAN [view interactions] Computational no yes
MET_HUMAN [view interactions] Computational no yes
GNAO_HUMAN [view entry] [view interactions] Computational yes yes
PK3CB_HUMAN [view interactions] Computational no yes
RHG35_HUMAN [view interactions] Computational no yes
GNAI3_HUMAN [view entry] [view interactions] Computational yes yes
WASP_HUMAN [view interactions] Computational no yes
FCERA_HUMAN [view interactions] Computational no yes
SHB_HUMAN [view interactions] Computational no yes
WIPF2_HUMAN [view entry] [view interactions] Computational yes yes
FOS_HUMAN [view interactions] Computational no yes
TLN2_HUMAN [view entry] [view interactions] Computational yes yes
ARHG1_HUMAN [view interactions] Computational no no
RASN_HUMAN [view entry] [view interactions] Computational yes no
BLK_HUMAN [view interactions] Computational no no
VGFR2_HUMAN [view interactions] Computational no no
LPAR1_HUMAN [view entry] [view interactions] Computational yes no
ITA6_HUMAN [view interactions] Computational no yes
CDC42_HUMAN [view entry] [view interactions] Computational yes yes
ARHGC_HUMAN [view interactions] Computational no yes
PI3R6_HUMAN [view interactions] Computational no yes
CO4A3_HUMAN [view interactions] Computational no no
SHC2_HUMAN [view interactions] Computational no yes