FAK1_HUMAN
Isoform 6 (FRNK) does not contain a kinase domain and inhibits PTK2/FAK1 phosphorylation and signaling. Its enhanced expression can attenuate the nuclear accumulation of LPXN and limit its ability to enhance serum response factor (SRF)-dependent gene transcription. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002032 | DOC_WW_Pin1_4 | DOC | 907 | 912 | - |
| ELMI000405 | LIG_SH2_GRB2like | LIG | 925 | 928 | - |
| ELMI002126 | LIG_SH2_SRC | LIG | 397 | 400 | - |
| ELMI002195 | LIG_SH3_2 | LIG | 712 | 717 | - |
| ELMI001460 | MOD_ProDKin_1 | MOD | 907 | 913 | - |
| ELMI002032 | DOC_WW_Pin1_4 | DOC | 907 | 912 | - |
| ELMI000405 | LIG_SH2_GRB2like | LIG | 925 | 928 | - |
| ELMI002126 | LIG_SH2_SRC | LIG | 397 | 400 | - |
| ELMI002195 | LIG_SH3_2 | LIG | 712 | 717 | - |
| ELMI001460 | MOD_ProDKin_1 | MOD | 907 | 913 | - |
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FAK1_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 33.8235 | 4 | yes |
| GO:0043168 | anion binding | 33.8235 | 4 | yes |
| GO:0019901 | protein kinase binding | 31.6176 | 5 | yes |
| GO:0000166 | nucleotide binding | 30.8824 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 30.8824 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 29.4118 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.4118 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 26.4706 | 6 | yes |
| GO:0043169 | cation binding | 25.7353 | 4 | no |
| GO:0046872 | metal ion binding | 25.7353 | 5 | no |
| GO:0005524 | ATP binding | 25.0000 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 25.0000 | 5 | yes |
| GO:0016301 | kinase activity | 20.5882 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 20.5882 | 4 | yes |
| GO:0003723 | RNA binding | 20.5882 | 4 | no |
| GO:0003779 | actin binding | 12.5000 | 4 | yes |
| GO:0019902 | phosphatase binding | 12.5000 | 4 | yes |
| GO:0004713 | protein tyrosine kinase activity | 11.7647 | 4 | yes |
| GO:0019903 | protein phosphatase binding | 11.0294 | 5 | yes |
| GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 7.3529 | 5 | yes |
| GO:0042578 | phosphoric ester hydrolase activity | 7.3529 | 4 | yes |
| GO:0016791 | phosphatase activity | 6.6176 | 5 | yes |
| GO:0042169 | SH2 domain binding | 5.8824 | 4 | yes |
| GO:0004725 | protein tyrosine phosphatase activity | 4.4118 | 4 | yes |
| GO:0008432 | JUN kinase binding | 2.2059 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FAK1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 75.7353 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 68.3824 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 66.9118 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 65.4412 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 65.4412 | 4 | yes |
| GO:0010646 | regulation of cell communication | 64.7059 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 57.3529 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 54.4118 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 54.4118 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 54.4118 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 53.6765 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 52.2059 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 50.7353 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 50.7353 | 5 | yes |
| GO:0010468 | regulation of gene expression | 50.0000 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 46.3235 | 4 | yes |
| GO:0022607 | cellular component assembly | 44.8529 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 44.8529 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 42.6471 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 41.9118 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 41.9118 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 40.4412 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 40.4412 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 38.9706 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 38.9706 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 38.2353 | 6 | yes |
| GO:0006996 | organelle organization | 38.2353 | 4 | no |
| GO:0051049 | regulation of transport | 38.2353 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 37.5000 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 37.5000 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 37.5000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 36.7647 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 35.2941 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 35.2941 | 6 | no |
| GO:0060341 | regulation of cellular localization | 34.5588 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 34.5588 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 34.5588 | 6 | no |
| GO:0009894 | regulation of catabolic process | 33.8235 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 33.0882 | 4 | no |
| GO:0071310 | cellular response to organic substance | 33.0882 | 4 | no |
| GO:0030030 | cell projection organization | 32.3529 | 4 | yes |
| GO:0036211 | protein modification process | 32.3529 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 32.3529 | 4 | yes |
| GO:0043412 | macromolecule modification | 32.3529 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 31.6176 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 31.6176 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 31.6176 | 4 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 31.6176 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 31.6176 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 30.8824 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 30.8824 | 6 | no |
| GO:0008104 | protein localization | 30.8824 | 4 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 30.1471 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 30.1471 | 5 | yes |
| GO:0032880 | regulation of protein localization | 30.1471 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 29.4118 | 4 | yes |
| GO:0007169 | cell surface receptor protein tyrosine kinase signaling pathway | 29.4118 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 29.4118 | 4 | yes |
| GO:0080134 | regulation of response to stress | 29.4118 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 27.9412 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 27.9412 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 27.9412 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 27.9412 | 4 | yes |
| GO:0010648 | negative regulation of cell communication | 27.9412 | 5 | no |
| GO:0023057 | negative regulation of signaling | 27.9412 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 27.2059 | 7 | yes |
| GO:0042325 | regulation of phosphorylation | 27.2059 | 7 | yes |
| GO:0010243 | response to organonitrogen compound | 27.2059 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 26.4706 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 26.4706 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.4706 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.4706 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.4706 | 6 | no |
| GO:0030155 | regulation of cell adhesion | 25.7353 | 4 | yes |
| GO:0031401 | positive regulation of protein modification process | 25.7353 | 7 | yes |
| GO:0009968 | negative regulation of signal transduction | 25.7353 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 25.7353 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 25.0000 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 25.0000 | 6 | yes |
| GO:0043066 | negative regulation of apoptotic process | 24.2647 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 24.2647 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 24.2647 | 5 | yes |
| GO:2000145 | regulation of cell motility | 24.2647 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 24.2647 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 23.5294 | 4 | no |
| GO:0002684 | positive regulation of immune system process | 23.5294 | 4 | yes |
| GO:0030162 | regulation of proteolysis | 23.5294 | 6 | yes |
| GO:0030334 | regulation of cell migration | 23.5294 | 5 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 22.7941 | 5 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 22.7941 | 5 | no |
| GO:1903829 | positive regulation of protein localization | 22.0588 | 5 | no |
| GO:0050776 | regulation of immune response | 22.0588 | 4 | yes |
| GO:0007010 | cytoskeleton organization | 22.0588 | 5 | no |
| GO:0010628 | positive regulation of gene expression | 22.0588 | 7 | no |
| GO:0016310 | phosphorylation | 21.3235 | 5 | yes |
| GO:0043085 | positive regulation of catalytic activity | 21.3235 | 4 | yes |
| GO:0051129 | negative regulation of cellular component organization | 21.3235 | 5 | no |
| GO:0060284 | regulation of cell development | 20.5882 | 5 | no |
| GO:0045597 | positive regulation of cell differentiation | 20.5882 | 5 | yes |
| GO:0051338 | regulation of transferase activity | 20.5882 | 4 | yes |
| GO:0051050 | positive regulation of transport | 20.5882 | 4 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 19.8529 | 8 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 19.8529 | 6 | yes |
| GO:0018193 | peptidyl-amino acid modification | 19.8529 | 5 | yes |
| GO:0031175 | neuron projection development | 19.8529 | 6 | yes |
| GO:0042327 | positive regulation of phosphorylation | 19.8529 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 19.8529 | 7 | yes |
| GO:0006468 | protein phosphorylation | 18.3824 | 5 | yes |
| GO:0009896 | positive regulation of catabolic process | 18.3824 | 5 | yes |
| GO:0045862 | positive regulation of proteolysis | 18.3824 | 7 | yes |
| GO:0040017 | positive regulation of locomotion | 17.6471 | 4 | yes |
| GO:0043549 | regulation of kinase activity | 17.6471 | 5 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 17.6471 | 6 | yes |
| GO:2000147 | positive regulation of cell motility | 17.6471 | 5 | yes |
| GO:0030335 | positive regulation of cell migration | 16.9118 | 6 | yes |
| GO:0045859 | regulation of protein kinase activity | 16.9118 | 6 | yes |
| GO:0050778 | positive regulation of immune response | 16.1765 | 5 | yes |
| GO:0051336 | regulation of hydrolase activity | 15.4412 | 4 | yes |
| GO:0010810 | regulation of cell-substrate adhesion | 13.9706 | 5 | yes |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 13.9706 | 7 | yes |
| GO:0022407 | regulation of cell-cell adhesion | 13.2353 | 5 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 13.2353 | 5 | yes |
| GO:0038127 | ERBB signaling pathway | 13.2353 | 6 | yes |
| GO:0051347 | positive regulation of transferase activity | 13.2353 | 5 | yes |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 13.2353 | 5 | yes |
| GO:0033674 | positive regulation of kinase activity | 11.7647 | 6 | yes |
| GO:0045860 | positive regulation of protein kinase activity | 11.7647 | 7 | yes |
| GO:0001952 | regulation of cell-matrix adhesion | 11.0294 | 6 | yes |
| GO:0002429 | immune response-activating cell surface receptor signaling pathway | 11.0294 | 4 | yes |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 11.0294 | 4 | yes |
| GO:0007411 | axon guidance | 11.0294 | 8 | yes |
| GO:0022604 | regulation of cell morphogenesis | 11.0294 | 5 | yes |
| GO:0097485 | neuron projection guidance | 11.0294 | 7 | yes |
| GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 11.0294 | 8 | yes |
| GO:0007173 | epidermal growth factor receptor signaling pathway | 10.2941 | 7 | yes |
| GO:0010632 | regulation of epithelial cell migration | 10.2941 | 4 | yes |
| GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 10.2941 | 6 | yes |
| GO:0002685 | regulation of leukocyte migration | 9.5588 | 4 | yes |
| GO:0046777 | protein autophosphorylation | 9.5588 | 6 | yes |
| GO:0051896 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 9.5588 | 6 | yes |
| GO:1901888 | regulation of cell junction assembly | 9.5588 | 5 | yes |
| GO:1903034 | regulation of response to wounding | 9.5588 | 5 | yes |
| GO:0007162 | negative regulation of cell adhesion | 8.8235 | 5 | yes |
| GO:0007229 | integrin-mediated signaling pathway | 8.8235 | 4 | yes |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 8.8235 | 6 | yes |
| GO:0018212 | peptidyl-tyrosine modification | 8.8235 | 6 | yes |
| GO:0048013 | ephrin receptor signaling pathway | 8.0882 | 6 | yes |
| GO:0070663 | regulation of leukocyte proliferation | 8.0882 | 5 | yes |
| GO:0071675 | regulation of mononuclear cell migration | 8.0882 | 5 | yes |
| GO:0010594 | regulation of endothelial cell migration | 7.3529 | 5 | yes |
| GO:0010634 | positive regulation of epithelial cell migration | 7.3529 | 5 | yes |
| GO:0038093 | Fc receptor signaling pathway | 7.3529 | 5 | yes |
| GO:0051893 | regulation of focal adhesion assembly | 6.6176 | 7 | yes |
| GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 6.6176 | 7 | yes |
| GO:0090109 | regulation of cell-substrate junction assembly | 6.6176 | 6 | yes |
| GO:0150116 | regulation of cell-substrate junction organization | 6.6176 | 5 | yes |
| GO:0002687 | positive regulation of leukocyte migration | 5.8824 | 5 | yes |
| GO:0022408 | negative regulation of cell-cell adhesion | 5.8824 | 6 | yes |
| GO:0033628 | regulation of cell adhesion mediated by integrin | 5.8824 | 5 | yes |
| GO:0038094 | Fc-gamma receptor signaling pathway | 5.8824 | 6 | yes |
| GO:0050920 | regulation of chemotaxis | 5.8824 | 4 | yes |
| GO:1900024 | regulation of substrate adhesion-dependent cell spreading | 5.8824 | 6 | yes |
| GO:0002431 | Fc receptor mediated stimulatory signaling pathway | 5.1471 | 5 | yes |
| GO:0002688 | regulation of leukocyte chemotaxis | 5.1471 | 5 | yes |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.1471 | 4 | yes |
| GO:0050921 | positive regulation of chemotaxis | 5.1471 | 5 | yes |
| GO:0061041 | regulation of wound healing | 5.1471 | 6 | yes |
| GO:0070665 | positive regulation of leukocyte proliferation | 5.1471 | 6 | yes |
| GO:0002690 | positive regulation of leukocyte chemotaxis | 4.4118 | 6 | yes |
| GO:0010762 | regulation of fibroblast migration | 4.4118 | 6 | yes |
| GO:0035994 | response to muscle stretch | 4.4118 | 4 | yes |
| GO:0043087 | regulation of GTPase activity | 4.4118 | 5 | yes |
| GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 4.4118 | 6 | yes |
| GO:0060396 | growth hormone receptor signaling pathway | 4.4118 | 6 | yes |
| GO:0071677 | positive regulation of mononuclear cell migration | 4.4118 | 6 | yes |
| GO:0007172 | signal complex assembly | 3.6765 | 5 | yes |
| GO:0007178 | cell surface receptor protein serine/threonine kinase signaling pathway | 3.6765 | 5 | yes |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | 3.6765 | 7 | yes |
| GO:0010717 | regulation of epithelial to mesenchymal transition | 3.6765 | 5 | yes |
| GO:0010763 | positive regulation of fibroblast migration | 3.6765 | 7 | yes |
| GO:0050982 | detection of mechanical stimulus | 3.6765 | 4 | yes |
| GO:0141091 | transforming growth factor beta receptor superfamily signaling pathway | 3.6765 | 6 | yes |
| GO:2000209 | regulation of anoikis | 3.6765 | 6 | yes |
| GO:2000811 | negative regulation of anoikis | 3.6765 | 7 | yes |
| GO:0010758 | regulation of macrophage chemotaxis | 2.9412 | 6 | yes |
| GO:0045667 | regulation of osteoblast differentiation | 2.9412 | 5 | yes |
| GO:0071622 | regulation of granulocyte chemotaxis | 2.9412 | 6 | yes |
| GO:1903036 | positive regulation of response to wounding | 2.9412 | 5 | yes |
| GO:1905521 | regulation of macrophage migration | 2.9412 | 6 | yes |
| GO:0001890 | placenta development | 2.2059 | 4 | yes |
| GO:0003007 | heart morphogenesis | 2.2059 | 4 | yes |
| GO:0010718 | positive regulation of epithelial to mesenchymal transition | 2.2059 | 5 | yes |
| GO:0010759 | positive regulation of macrophage chemotaxis | 2.2059 | 7 | yes |
| GO:0035995 | detection of muscle stretch | 2.2059 | 5 | yes |
| GO:0090303 | positive regulation of wound healing | 2.2059 | 6 | yes |
| GO:0120040 | regulation of macrophage proliferation | 2.2059 | 6 | yes |
| GO:0120041 | positive regulation of macrophage proliferation | 2.2059 | 7 | yes |
| GO:1905523 | positive regulation of macrophage migration | 2.2059 | 7 | yes |
| GO:0038007 | netrin-activated signaling pathway | 1.4706 | 4 | yes |
Disease
No data found.
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| EPHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| L1CAM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTN11_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DCC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ANGL4_HUMAN | [view interactions] | Low throughput | no | no |
| EPHA2_HUMAN | [view interactions] | Low throughput | no | no |
| CRK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PTH2_HUMAN | [view interactions] | Low throughput | no | yes |
| PK3CA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | Low throughput | no | no |
| STAT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PTAFR_HUMAN | [view interactions] | Low throughput | no | yes |
| PI51C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRB7_HUMAN | [view interactions] | Low throughput | no | no |
| PTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STAT3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| YES_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITAV_HUMAN | [view interactions] | Low throughput | no | yes |
| PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IRS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CASL_HUMAN | [view interactions] | Low throughput | no | yes |
| NEO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EFS_HUMAN | [view interactions] | Low throughput | no | no |
| SOCS3_HUMAN | [view interactions] | Low throughput | no | yes |
| TRIP6_HUMAN | [view interactions] | Low throughput | no | yes |
| BCL2_HUMAN | [view interactions] | Low throughput | no | no |
| CIB1_HUMAN | [view interactions] | Low throughput | no | no |
| GIT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITB5_HUMAN | [view interactions] | Low throughput | no | yes |
| JIP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CCR5_HUMAN | [view interactions] | Low throughput | no | no |
| GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CXCR4_HUMAN | [view interactions] | Low throughput | no | no |
| BMX_HUMAN | [view interactions] | Low throughput | no | no |
| PKD1_HUMAN | [view interactions] | Low throughput | no | yes |
| TSC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | Low throughput | no | no |
| FGR_HUMAN | [view interactions] | Low throughput | no | no |
| TLN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GELS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AMPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BIN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KSYK_HUMAN | [view interactions] | Low throughput | no | no |
| ITB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| RBCC1_HUMAN | [view interactions] | Low throughput | no | no |
| NCK1_HUMAN | [view interactions] | Low throughput | no | yes |
| NCK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSK_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STAP2_HUMAN | [view interactions] | Low throughput | no | yes |
| CHIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RBNS5_HUMAN | [view interactions] | Low throughput | no | yes |
| TRI72_HUMAN | [view interactions] | Low throughput | no | no |
| UBE2H_HUMAN | [view interactions] | Low throughput | no | yes |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CADH5_HUMAN | [view interactions] | Low throughput | no | yes |
| NMDE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MERL_HUMAN | [view interactions] | Low throughput | no | yes |
| CBLB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SOCS1_HUMAN | [view interactions] | Low throughput | no | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEP_HUMAN | [view interactions] | Low throughput | no | no |
| XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
| PBIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MK08_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| TBK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCI_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TMG4_HUMAN | [view interactions] | Low throughput | no | yes |
| SKP2_HUMAN | [view interactions] | Low throughput | no | yes |
| MISP_HUMAN | [view interactions] | Low throughput | no | no |
| CDK4_HUMAN | [view interactions] | Low throughput | no | no |
| CDK6_HUMAN | [view interactions] | Low throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| EZRI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RHG26_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MDM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DMD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GATA4_HUMAN | [view interactions] | Low throughput | no | no |
| LYAM2_HUMAN | [view interactions] | Low throughput | no | no |
| ZFY21_HUMAN | [view interactions] | Low throughput | no | yes |
| G3P_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BCAR1_HUMAN | [view interactions] | Low throughput | no | yes |
| FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LPXN_HUMAN | [view interactions] | Low throughput | no | yes |
| TGFI1_HUMAN | [view interactions] | Low throughput | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RHOU_HUMAN | [view interactions] | Low throughput | no | no |
| PAXI_HUMAN | [view interactions] | Low throughput | no | yes |
| FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TENS3_HUMAN | [view interactions] | Low throughput | no | no |
| LYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ERBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PP1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| SRBS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTN23_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD36_HUMAN | [view interactions] | Low throughput | no | no |
| CADM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CD4_HUMAN | [view interactions] | Low throughput | no | no |
| MEF2C_HUMAN | [view interactions] | Low throughput | no | yes |
| ELOB_HUMAN | [view interactions] | Low throughput | no | no |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| E41L5_HUMAN | [view interactions] | High throughput | no | no |
| SSF1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM28_HUMAN | [view interactions] | High throughput | no | yes |
| DDX43_HUMAN | [view interactions] | High throughput | no | no |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS1_HUMAN | [view interactions] | High throughput | no | yes |
| UTP18_HUMAN | [view interactions] | High throughput | no | yes |
| CCNA1_HUMAN | [view interactions] | High throughput | no | no |
| DVLP1_HUMAN | [view interactions] | High throughput | no | no |
| DVL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAL_HUMAN | [view interactions] | High throughput | no | no |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| SAE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH21A_HUMAN | [view interactions] | High throughput | no | no |
| DOK4_HUMAN | [view interactions] | High throughput | no | yes |
| SH22A_HUMAN | [view interactions] | High throughput | no | no |
| SH21B_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSP13_HUMAN | [view interactions] | High throughput | no | yes |
| MORC3_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIAS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RET_HUMAN | [view interactions] | High throughput | no | yes |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VGFR1_HUMAN | [view interactions] | High throughput | no | no |
| SOCS2_HUMAN | [view interactions] | High throughput | no | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| DEFI6_HUMAN | [view interactions] | High throughput | no | no |
| PTN6_HUMAN | [view interactions] | High throughput | no | no |
| HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DOCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDC6I_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| KGP1_HUMAN | [view interactions] | High throughput | no | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
| SWP70_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAGA9_HUMAN | [view interactions] | High throughput | no | no |
| PIP_HUMAN | [view interactions] | High throughput | no | no |
| TGM1_HUMAN | [view interactions] | High throughput | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BSPRY_HUMAN | [view interactions] | High throughput | no | no |
| MND1_HUMAN | [view interactions] | High throughput | no | no |
| PLCC_HUMAN | [view interactions] | High throughput | no | no |
| GLYC_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| RBM25_HUMAN | [view interactions] | High throughput | no | yes |
| ATG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUL_HUMAN | [view interactions] | High throughput | no | yes |
| PLK1_HUMAN | [view interactions] | High throughput | no | yes |
| FAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIE2_HUMAN | [view interactions] | High throughput | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI15_HUMAN | [view interactions] | High throughput | no | no |
| OTU6B_HUMAN | [view interactions] | High throughput | no | yes |
| TRM6_HUMAN | [view interactions] | High throughput | no | yes |
| MICA1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEC1_HUMAN | [view interactions] | High throughput | no | yes |
| BBS10_HUMAN | [view interactions] | High throughput | no | no |
| NCAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DX39A_HUMAN | [view interactions] | High throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| ES8L2_HUMAN | [view interactions] | High throughput | no | yes |
| DIAP1_HUMAN | [view interactions] | High throughput | no | yes |
| F13A_HUMAN | [view interactions] | High throughput | no | no |
| ACADM_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HES1_HUMAN | [view interactions] | High throughput | no | no |
| FER_HUMAN | [view interactions] | High throughput | no | yes |
| MUTA_HUMAN | [view interactions] | High throughput | no | yes |
| NACAD_HUMAN | [view interactions] | High throughput | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NASP_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMS1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN331_HUMAN | [view interactions] | High throughput | no | no |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AB1IP_HUMAN | [view interactions] | High throughput | no | no |
| PRPK_HUMAN | [view interactions] | High throughput | no | yes |
| NUP50_HUMAN | [view interactions] | High throughput | no | yes |
| EBP_HUMAN | [view interactions] | High throughput | no | no |
| VPS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANKH1_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN5_HUMAN | [view interactions] | High throughput | no | yes |
| ANR26_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAI2_HUMAN | [view interactions] | High throughput | no | no |
| CCD18_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| CP131_HUMAN | [view interactions] | High throughput | no | no |
| CIP2A_HUMAN | [view interactions] | High throughput | no | yes |
| ERAL1_HUMAN | [view interactions] | High throughput | no | yes |
| ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F193A_HUMAN | [view interactions] | High throughput | no | yes |
| GTPB1_HUMAN | [view interactions] | High throughput | no | yes |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| PAPD1_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUDC3_HUMAN | [view interactions] | High throughput | no | yes |
| RL34_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SPS2L_HUMAN | [view interactions] | High throughput | no | yes |
| GRAP_HUMAN | [view interactions] | High throughput | no | no |
| WDR83_HUMAN | [view interactions] | High throughput | no | yes |
| THMS1_HUMAN | [view interactions] | High throughput | no | no |
| ALMS1_HUMAN | [view interactions] | High throughput | no | no |
| SOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SURF6_HUMAN | [view interactions] | High throughput | no | yes |
| CE152_HUMAN | [view interactions] | High throughput | no | yes |
| P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFT74_HUMAN | [view interactions] | High throughput | no | yes |
| RFC4_HUMAN | [view interactions] | High throughput | no | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFC1_HUMAN | [view interactions] | High throughput | no | yes |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM34_HUMAN | [view interactions] | High throughput | no | yes |
| MAST4_HUMAN | [view interactions] | High throughput | no | no |
| FNTA_HUMAN | [view interactions] | High throughput | no | yes |
| OFD1_HUMAN | [view interactions] | High throughput | no | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| PTN12_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1_HUMAN | [view interactions] | High throughput | no | yes |
| RL10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOSX_HUMAN | [view interactions] | High throughput | no | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCOF_HUMAN | [view interactions] | High throughput | no | yes |
| DIC_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS2_HUMAN | [view interactions] | High throughput | no | yes |
| SMD1_HUMAN | [view interactions] | High throughput | no | yes |
| BOP1_HUMAN | [view interactions] | High throughput | no | yes |
| TCHP_HUMAN | [view interactions] | High throughput | no | yes |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSR1_HUMAN | [view interactions] | High throughput | no | no |
| TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF8_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| RL7L_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| EXOS8_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK1_HUMAN | [view interactions] | High throughput | no | yes |
| CG050_HUMAN | [view interactions] | High throughput | no | yes |
| GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| CH033_HUMAN | [view interactions] | High throughput | no | yes |