NCAM1_HUMAN
Evidence for PS localization
Functions
(Microbial infection) Acts as a receptor for Zika virus. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NCAM1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 38.0000 | 4 | no |
| GO:0000166 | nucleotide binding | 36.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 36.0000 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 36.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.0000 | 4 | no |
| GO:0043169 | cation binding | 30.0000 | 4 | no |
| GO:0046872 | metal ion binding | 30.0000 | 5 | no |
| GO:0019900 | kinase binding | 22.0000 | 4 | no |
| GO:0001618 | virus receptor activity | 6.0000 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NCAM1_HUMAN |
|---|---|---|---|---|
| GO:0010646 | regulation of cell communication | 66.0000 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 62.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 60.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 60.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 42.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 40.0000 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 40.0000 | 4 | no |
| GO:0030030 | cell projection organization | 40.0000 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 38.0000 | 5 | no |
| GO:0051049 | regulation of transport | 36.0000 | 4 | no |
| GO:0006996 | organelle organization | 36.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 36.0000 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 36.0000 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 36.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 36.0000 | 4 | no |
| GO:0031399 | regulation of protein modification process | 34.0000 | 6 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 34.0000 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 34.0000 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 32.0000 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 32.0000 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 32.0000 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 32.0000 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 30.0000 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 30.0000 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 30.0000 | 5 | no |
| GO:0036211 | protein modification process | 30.0000 | 4 | no |
| GO:0043412 | macromolecule modification | 30.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 28.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 28.0000 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 28.0000 | 7 | no |
| GO:0031175 | neuron projection development | 28.0000 | 6 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 28.0000 | 4 | no |
| GO:0008104 | protein localization | 28.0000 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 26.0000 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 26.0000 | 7 | no |
| GO:0009892 | negative regulation of metabolic process | 26.0000 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 26.0000 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.0000 | 6 | no |
| GO:0050807 | regulation of synapse organization | 26.0000 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 26.0000 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 26.0000 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 26.0000 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 26.0000 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 26.0000 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 24.0000 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 24.0000 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.0000 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 24.0000 | 7 | no |
| GO:0043085 | positive regulation of catalytic activity | 24.0000 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.0000 | 4 | no |
| GO:0006915 | apoptotic process | 24.0000 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 24.0000 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.0000 | 6 | no |
| GO:0141124 | intracellular signaling cassette | 24.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 24.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 24.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.0000 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.0000 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 22.0000 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 22.0000 | 5 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.0000 | 7 | no |
| GO:0009894 | regulation of catabolic process | 22.0000 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 22.0000 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 22.0000 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.0000 | 4 | no |
| GO:0043066 | negative regulation of apoptotic process | 22.0000 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 22.0000 | 5 | no |
| GO:0048812 | neuron projection morphogenesis | 22.0000 | 5 | no |
| GO:0050890 | cognition | 22.0000 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 22.0000 | 5 | no |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 22.0000 | 4 | no |
| GO:0007411 | axon guidance | 10.0000 | 8 | yes |
| GO:0097485 | neuron projection guidance | 10.0000 | 7 | yes |
| GO:0001837 | epithelial to mesenchymal transition | 8.0000 | 5 | yes |
| GO:0048762 | mesenchymal cell differentiation | 8.0000 | 4 | yes |
| GO:0071679 | commissural neuron axon guidance | 6.0000 | 9 | yes |
| GO:2001260 | regulation of semaphorin-plexin signaling pathway | 4.0000 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PRIO_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCAM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| FGFR2_HUMAN | [view interactions] | Low throughput | no | yes |
| SIA8B_HUMAN | [view interactions] | Low throughput | no | yes |
| KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MK_HUMAN | [view interactions] | Low throughput | no | no |
| UBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTPRA_HUMAN | [view interactions] | Low throughput | no | yes |
| PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AN32A_HUMAN | [view interactions] | Low throughput | no | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PACN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPHA3_HUMAN | [view interactions] | Low throughput | no | yes |
| NCAN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| SPTB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | Low throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
| ARMC1_HUMAN | [view interactions] | High throughput | no | yes |
| SDC1_HUMAN | [view interactions] | High throughput | no | no |
| REEP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RETR3_HUMAN | [view interactions] | High throughput | no | yes |
| REEP1_HUMAN | [view interactions] | High throughput | no | yes |
| T185A_HUMAN | [view interactions] | High throughput | no | no |
| ZNT4_HUMAN | [view interactions] | High throughput | no | no |
| OPCM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| BRF2_HUMAN | [view interactions] | High throughput | no | yes |
| SIGL9_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX4_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| DGUOK_HUMAN | [view interactions] | High throughput | no | yes |
| KTU_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| CP2S1_HUMAN | [view interactions] | High throughput | no | no |
| ISG20_HUMAN | [view interactions] | High throughput | no | no |
| NICA_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CERS2_HUMAN | [view interactions] | High throughput | no | no |
| PTH2R_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| KTAP2_HUMAN | [view interactions] | High throughput | no | no |
| RYK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRPH2_HUMAN | [view interactions] | High throughput | no | no |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| CLC4A_HUMAN | [view interactions] | High throughput | no | no |
| REEP6_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| RN207_HUMAN | [view interactions] | High throughput | no | no |
| DSCAM_HUMAN | [view interactions] | High throughput | no | yes |
| CNTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AR13B_HUMAN | [view interactions] | High throughput | no | yes |
| ARL14_HUMAN | [view interactions] | High throughput | no | no |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTK7_HUMAN | [view interactions] | High throughput | no | yes |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |