Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KAP1_HUMAN

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in KAP1_HUMAN
GO:0043168 anion binding 29.2135 4 yes
GO:0000166 nucleotide binding 28.0899 4 yes
GO:0017076 purine nucleotide binding 28.0899 5 yes
GO:0032555 purine ribonucleotide binding 26.9663 4 yes
GO:0030554 adenyl nucleotide binding 25.8427 6 yes
GO:0032559 adenyl ribonucleotide binding 24.7191 5 yes
GO:0035639 purine ribonucleoside triphosphate binding 21.3483 4 no
GO:0019900 kinase binding 20.2247 4 yes
GO:0043169 cation binding 20.2247 4 no
GO:0046872 metal ion binding 20.2247 5 no
GO:0019901 protein kinase binding 16.8539 5 yes
GO:0019887 protein kinase regulator activity 5.6180 4 yes
GO:0030551 cyclic nucleotide binding 5.6180 5 yes
GO:0030552 cAMP binding 5.6180 5 yes
GO:0034236 protein kinase A catalytic subunit binding 5.6180 4 yes
GO:0004860 protein kinase inhibitor activity 4.4944 5 yes
GO:0004862 cAMP-dependent protein kinase inhibitor activity 4.4944 6 yes
GO:0008603 cAMP-dependent protein kinase regulator activity 4.4944 5 yes
GO:0019210 kinase inhibitor activity 4.4944 4 yes
GO:0030291 protein serine/threonine kinase inhibitor activity 4.4944 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KAP1_HUMAN
GO:0048522 positive regulation of cellular process 44.9438 4 yes
GO:0010646 regulation of cell communication 40.4494 4 yes
GO:0060255 regulation of macromolecule metabolic process 40.4494 4 yes
GO:0031323 regulation of cellular metabolic process 37.0787 4 yes
GO:0080090 regulation of primary metabolic process 35.9551 4 yes
GO:0048523 negative regulation of cellular process 34.8315 4 yes
GO:0008104 protein localization 34.8315 4 no
GO:0006996 organelle organization 33.7079 4 no
GO:0022607 cellular component assembly 31.4607 4 no
GO:0051128 regulation of cellular component organization 31.4607 4 no
GO:0051049 regulation of transport 30.3371 4 yes
GO:0009966 regulation of signal transduction 28.0899 4 yes
GO:0009889 regulation of biosynthetic process 28.0899 4 no
GO:0010468 regulation of gene expression 28.0899 6 no
GO:0010556 regulation of macromolecule biosynthetic process 28.0899 5 no
GO:0031326 regulation of cellular biosynthetic process 28.0899 5 no
GO:0051246 regulation of protein metabolic process 25.8427 5 yes
GO:0010647 positive regulation of cell communication 23.5955 5 yes
GO:0023056 positive regulation of signaling 23.5955 4 yes
GO:0071702 organic substance transport 23.5955 4 no
GO:0006796 phosphate-containing compound metabolic process 22.4719 4 yes
GO:0009892 negative regulation of metabolic process 22.4719 4 yes
GO:0009893 positive regulation of metabolic process 22.4719 4 no
GO:0010605 negative regulation of macromolecule metabolic process 21.3483 5 yes
GO:0043412 macromolecule modification 21.3483 4 yes
GO:0048584 positive regulation of response to stimulus 21.3483 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 21.3483 5 no
GO:0071705 nitrogen compound transport 21.3483 4 no
GO:0036211 protein modification process 20.2247 4 yes
GO:0050804 modulation of chemical synaptic transmission 20.2247 5 yes
GO:0099177 regulation of trans-synaptic signaling 20.2247 4 yes
GO:0043933 protein-containing complex organization 20.2247 4 no
GO:0051130 positive regulation of cellular component organization 20.2247 5 no
GO:0061024 membrane organization 20.2247 4 no
GO:0009967 positive regulation of signal transduction 17.9775 5 yes
GO:0016310 phosphorylation 17.9775 5 yes
GO:0031324 negative regulation of cellular metabolic process 16.8539 5 yes
GO:0031399 regulation of protein modification process 16.8539 6 yes
GO:0006468 protein phosphorylation 15.7303 5 yes
GO:0051240 positive regulation of multicellular organismal process 15.7303 4 yes
GO:0060627 regulation of vesicle-mediated transport 14.6067 4 yes
GO:0019220 regulation of phosphate metabolic process 13.4831 6 yes
GO:0051174 regulation of phosphorus metabolic process 13.4831 5 yes
GO:0001932 regulation of protein phosphorylation 11.2360 7 yes
GO:0042325 regulation of phosphorylation 11.2360 7 yes
GO:0051248 negative regulation of protein metabolic process 11.2360 6 yes
GO:0080134 regulation of response to stress 11.2360 4 yes
GO:0044057 regulation of system process 10.1124 4 yes
GO:0050890 cognition 10.1124 4 yes
GO:0051338 regulation of transferase activity 10.1124 4 yes
GO:0031400 negative regulation of protein modification process 7.8652 7 yes
GO:0043086 negative regulation of catalytic activity 7.8652 4 yes
GO:0043549 regulation of kinase activity 7.8652 5 yes
GO:0045859 regulation of protein kinase activity 7.8652 6 yes
GO:0050806 positive regulation of synaptic transmission 7.8652 5 yes
GO:0010563 negative regulation of phosphorus metabolic process 6.7416 6 yes
GO:0045936 negative regulation of phosphate metabolic process 6.7416 7 yes
GO:0051348 negative regulation of transferase activity 5.6180 5 yes
GO:0001933 negative regulation of protein phosphorylation 4.4944 8 yes
GO:0006469 negative regulation of protein kinase activity 4.4944 7 yes
GO:0031644 regulation of nervous system process 4.4944 5 yes
GO:0033673 negative regulation of kinase activity 4.4944 6 yes
GO:0042326 negative regulation of phosphorylation 4.4944 8 yes
GO:0071900 regulation of protein serine/threonine kinase activity 4.4944 7 yes
GO:0071901 negative regulation of protein serine/threonine kinase activity 4.4944 8 yes
GO:0098815 modulation of excitatory postsynaptic potential 4.4944 4 yes
GO:1900271 regulation of long-term synaptic potentiation 4.4944 4 yes
GO:2000479 regulation of cAMP-dependent protein kinase activity 4.4944 8 yes
GO:2000480 negative regulation of cAMP-dependent protein kinase activity 4.4944 9 yes
GO:1900273 positive regulation of long-term synaptic potentiation 3.3708 5 yes
GO:2000463 positive regulation of excitatory postsynaptic potential 3.3708 5 yes
GO:0098693 regulation of synaptic vesicle cycle 2.2472 5 yes
GO:1903365 regulation of fear response 2.2472 4 yes
GO:1903367 positive regulation of fear response 2.2472 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
KAP0_HUMAN [view entry] [view interactions] Low throughput yes yes
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
AKAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
KAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
MED8_HUMAN [view interactions] High throughput no yes
IGFN1_HUMAN [view interactions] High throughput no no
ZN177_HUMAN [view interactions] High throughput no no
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
DACH1_HUMAN [view interactions] High throughput no no
PGTB2_HUMAN [view interactions] High throughput no yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
SYT11_HUMAN [view entry] [view interactions] High throughput yes yes
DCR1C_HUMAN [view interactions] High throughput no no
LNX2_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
NOX5_HUMAN [view interactions] High throughput no no
RPGF5_HUMAN [view interactions] High throughput no yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
FACD2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
RIGI_HUMAN [view interactions] High throughput no yes
TBB8_HUMAN [view interactions] High throughput no no
TALD3_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
MAP10_HUMAN [view interactions] High throughput no no
CCD96_HUMAN [view interactions] High throughput no no
GSK3A_HUMAN [view interactions] High throughput no yes
GATB_HUMAN [view interactions] High throughput no yes
GREB1_HUMAN [view interactions] High throughput no yes
FA43A_HUMAN [view interactions] High throughput no no
PREX2_HUMAN [view interactions] High throughput no no
DOXA2_HUMAN [view interactions] High throughput no no
CEP43_HUMAN [view interactions] High throughput no no
BMP1_HUMAN [view interactions] High throughput no yes
DJC13_HUMAN [view entry] [view interactions] High throughput yes yes
DUS16_HUMAN [view interactions] High throughput no yes
FLIP1_HUMAN [view entry] [view interactions] High throughput yes no
BCAT1_HUMAN [view interactions] High throughput no no
FRMD1_HUMAN [view interactions] High throughput no no
PLD1_HUMAN [view interactions] High throughput no no
SULF2_HUMAN [view interactions] High throughput no yes
RAI14_HUMAN [view interactions] High throughput no yes
AASD1_HUMAN [view interactions] High throughput no yes
ZN564_HUMAN [view interactions] High throughput no no
ZN507_HUMAN [view interactions] High throughput no no
IQCF2_HUMAN [view interactions] High throughput no no
IMDH1_HUMAN [view interactions] High throughput no yes
TIMP3_HUMAN [view interactions] High throughput no no
AKA11_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
FGF11_HUMAN [view interactions] High throughput no no
TFDP3_HUMAN [view interactions] High throughput no no
KLH28_HUMAN [view interactions] High throughput no no
SENP3_HUMAN [view interactions] High throughput no yes
MCM5_HUMAN [view interactions] High throughput no no
PIGH_HUMAN [view interactions] High throughput no yes
LGMN_HUMAN [view interactions] High throughput no yes
MYH7_HUMAN [view interactions] High throughput no no
MYH8_HUMAN [view interactions] High throughput no no
ETFA_HUMAN [view interactions] High throughput no yes
AT1A4_HUMAN [view entry] [view interactions] High throughput yes no
CQ078_HUMAN [view interactions] High throughput no no
CCD32_HUMAN [view interactions] High throughput no yes
ZN623_HUMAN [view interactions] High throughput no no
DYR1A_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
ZN749_HUMAN [view interactions] High throughput no no
KPCA_HUMAN [view entry] [view interactions] High throughput yes yes
UBE2H_HUMAN [view interactions] High throughput no yes
CALU_HUMAN [view interactions] High throughput no yes
DUS3L_HUMAN [view interactions] High throughput no yes
EF2K_HUMAN [view entry] [view interactions] High throughput yes no
THG1_HUMAN [view interactions] High throughput no yes
DCAF7_HUMAN [view interactions] High throughput no yes
AKAP9_HUMAN [view entry] [view interactions] High throughput yes yes
NXPE4_HUMAN [view interactions] High throughput no no
SMAD4_HUMAN [view interactions] High throughput no yes
GRIA2_HUMAN [view entry] [view interactions] High throughput yes yes
KCNQ2_HUMAN [view entry] [view interactions] High throughput yes yes
K0513_HUMAN [view entry] [view interactions] High throughput yes yes
ABCE1_HUMAN [view interactions] High throughput no yes
KAD1_HUMAN [view entry] [view interactions] High throughput yes yes
AP3S1_HUMAN [view entry] [view interactions] High throughput yes no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
DP13A_HUMAN [view entry] [view interactions] High throughput yes yes
VATG1_HUMAN [view entry] [view interactions] High throughput yes yes
BASP1_HUMAN [view entry] [view interactions] High throughput yes yes
CAC1B_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
KCC2G_HUMAN [view entry] [view interactions] High throughput yes yes
XPO2_HUMAN [view entry] [view interactions] High throughput yes no
CXAR_HUMAN [view interactions] High throughput no yes
DHRS1_HUMAN [view interactions] High throughput no yes
DLGP4_HUMAN [view entry] [view interactions] High throughput yes yes
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
ELAV4_HUMAN [view entry] [view interactions] High throughput yes yes
FKBP2_HUMAN [view interactions] High throughput no yes
GSLG1_HUMAN [view entry] [view interactions] High throughput yes yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
HM13_HUMAN [view interactions] High throughput no yes
HELZ_HUMAN [view interactions] High throughput no yes
ROAA_HUMAN [view entry] [view interactions] High throughput yes yes
HNRL2_HUMAN [view interactions] High throughput no yes
LRRC7_HUMAN [view entry] [view interactions] High throughput yes no
MARE2_HUMAN [view entry] [view interactions] High throughput yes yes
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
MRP_HUMAN [view entry] [view interactions] High throughput yes no
MESD_HUMAN [view interactions] High throughput no yes
MLEC_HUMAN [view interactions] High throughput no no
MPC2_HUMAN [view interactions] High throughput no yes
NACAM_HUMAN [view interactions] High throughput no no
NCAM1_HUMAN [view entry] [view interactions] High throughput yes no
NUCL_HUMAN [view interactions] High throughput no yes
NDUAA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA9_HUMAN [view entry] [view interactions] High throughput yes yes
NRCAM_HUMAN [view entry] [view interactions] High throughput yes no
OAT_HUMAN [view interactions] High throughput no yes
PDCD5_HUMAN [view interactions] High throughput no yes
PFD5_HUMAN [view interactions] High throughput no yes
PFKAL_HUMAN [view entry] [view interactions] High throughput yes yes
PHB2_HUMAN [view entry] [view interactions] High throughput yes yes
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
NCPR_HUMAN [view entry] [view interactions] High throughput yes yes
KPCB_HUMAN [view entry] [view interactions] High throughput yes yes
KPCG_HUMAN [view entry] [view interactions] High throughput yes yes
PSB6_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD7_HUMAN [view interactions] High throughput no yes
PYGB_HUMAN [view entry] [view interactions] High throughput yes no
RL18A_HUMAN [view entry] [view interactions] High throughput yes yes
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
RL8_HUMAN [view entry] [view interactions] High throughput yes yes
RRBP1_HUMAN [view entry] [view interactions] High throughput yes yes
SFXN3_HUMAN [view entry] [view interactions] High throughput yes yes
SFXN5_HUMAN [view entry] [view interactions] High throughput yes no
MOT1_HUMAN [view interactions] High throughput no no
SNP25_HUMAN [view entry] [view interactions] High throughput yes yes
SODM_HUMAN [view entry] [view interactions] High throughput yes no
SPRL1_HUMAN [view interactions] High throughput no no
SPKAP_HUMAN [view interactions] High throughput no yes
STAU2_HUMAN [view entry] [view interactions] High throughput yes yes
SYN2_HUMAN [view entry] [view interactions] High throughput yes no
SNG1_HUMAN [view entry] [view interactions] High throughput yes yes
ZO1_HUMAN [view entry] [view interactions] High throughput yes no
TBA4A_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
YBOX1_HUMAN [view interactions] High throughput no yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
SCOT1_HUMAN [view entry] [view interactions] High throughput yes yes
IGHM_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
SNAG_HUMAN [view entry] [view interactions] High throughput yes yes
CF141_HUMAN [view interactions] High throughput no no
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
KAP3_HUMAN [view entry] [view interactions] High throughput yes yes
KAPCG_HUMAN [view interactions] High throughput no no
ERMAP_HUMAN [view interactions] High throughput no yes
SKP2_HUMAN [view interactions] High throughput no yes
MLF1_HUMAN [view entry] [view interactions] High throughput yes yes
RT15_HUMAN [view interactions] High throughput no yes
SFRP4_HUMAN [view interactions] High throughput no no
GP161_HUMAN [view interactions] High throughput no yes
KPRB_HUMAN [view interactions] High throughput no yes
H10_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
NUAK1_HUMAN [view interactions] High throughput no no
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
S30BP_HUMAN [view interactions] High throughput no yes
SHC3_HUMAN [view interactions] High throughput no yes
GNL3L_HUMAN [view interactions] High throughput no yes
GLIS2_HUMAN [view interactions] High throughput no no
LENG1_HUMAN [view interactions] High throughput no no
GPKOW_HUMAN [view interactions] High throughput no yes
ZNF35_HUMAN [view interactions] High throughput no no
SMG9_HUMAN [view interactions] High throughput no yes
CDN1A_HUMAN [view interactions] High throughput no no
ZN329_HUMAN [view interactions] High throughput no no
SH24A_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
RARG_HUMAN [view interactions] High throughput no yes
DPOE4_HUMAN [view interactions] High throughput no no
MY15B_HUMAN [view interactions] High throughput no no
P55G_HUMAN [view interactions] High throughput no yes
GA2L2_HUMAN [view interactions] High throughput no no
LMBL2_HUMAN [view interactions] High throughput no no
F161A_HUMAN [view interactions] High throughput no no
AKA28_HUMAN [view interactions] High throughput no no
CC103_HUMAN [view interactions] High throughput no no
EF2KT_HUMAN [view interactions] High throughput no no
BD1L2_HUMAN [view interactions] High throughput no no
VEZF1_HUMAN [view interactions] High throughput no yes
PRP18_HUMAN [view interactions] High throughput no yes
AAPK2_HUMAN [view interactions] High throughput no yes
SYTL4_HUMAN [view interactions] High throughput no yes
ZNF76_HUMAN [view interactions] High throughput no no
THA_HUMAN [view interactions] High throughput no yes
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
F90A1_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
T10IP_HUMAN [view interactions] High throughput no no
COX5B_HUMAN [view entry] [view interactions] High throughput yes yes
UACA_HUMAN [view interactions] High throughput no yes
CBX8_HUMAN [view interactions] High throughput no yes
NTAQ1_HUMAN [view interactions] High throughput no yes
ZMY19_HUMAN [view interactions] High throughput no yes
QRIC1_HUMAN [view interactions] High throughput no yes
KANK2_HUMAN [view entry] [view interactions] High throughput yes yes
PSMG1_HUMAN [view interactions] High throughput no yes
LNX1_HUMAN [view entry] [view interactions] High throughput yes yes
STK16_HUMAN [view interactions] High throughput no no
ZBT16_HUMAN [view interactions] High throughput no yes
CEP19_HUMAN [view interactions] High throughput no no
TEAD4_HUMAN [view interactions] High throughput no no
GOGA1_HUMAN [view interactions] High throughput no yes
KINH_HUMAN [view entry] [view interactions] High throughput yes no
TASO2_HUMAN [view interactions] High throughput no yes
NXF1_HUMAN [view interactions] High throughput no yes
GUC1A_HUMAN [view interactions] High throughput no no
PI5PA_HUMAN [view interactions] High throughput no no
UBC9_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CLUS_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
WNK1_HUMAN [view entry] [view interactions] High throughput yes no
ANS1A_HUMAN [view interactions] High throughput no yes
MBD3_HUMAN [view interactions] High throughput no yes
MTG8_HUMAN [view interactions] High throughput no yes
ZN410_HUMAN [view interactions] High throughput no no
CAMP1_HUMAN [view interactions] High throughput no yes
FCSD2_HUMAN [view interactions] High throughput no no
DTNB_HUMAN [view entry] [view interactions] High throughput yes no