Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KAP1_HUMAN

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in KAP1_HUMAN
GO:0017076 purine nucleotide binding 39.2857 4 yes
GO:0032555 purine ribonucleotide binding 37.5000 4 yes
GO:0030554 adenyl nucleotide binding 35.7143 5 yes
GO:0032559 adenyl ribonucleotide binding 33.9286 5 yes
GO:0019900 kinase binding 28.5714 4 yes
GO:0019901 protein kinase binding 26.7857 5 yes
GO:0035639 purine ribonucleoside triphosphate binding 26.7857 4 no
GO:0005524 ATP binding 23.2143 5 no
GO:0046872 metal ion binding 23.2143 4 no
GO:0004860 protein kinase inhibitor activity 12.5000 5 yes
GO:0019210 kinase inhibitor activity 12.5000 4 yes
GO:0019887 protein kinase regulator activity 12.5000 4 yes
GO:0034236 protein kinase A catalytic subunit binding 12.5000 4 yes
GO:0004862 cAMP-dependent protein kinase inhibitor activity 10.7143 6 yes
GO:0008603 cAMP-dependent protein kinase regulator activity 10.7143 5 yes
GO:0030291 protein serine/threonine kinase inhibitor activity 10.7143 6 yes
GO:0030551 cyclic nucleotide binding 10.7143 4 yes
GO:0030552 cAMP binding 10.7143 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KAP1_HUMAN
GO:0060255 regulation of macromolecule metabolic process 58.9286 4 yes
GO:0010646 regulation of cell communication 57.1429 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 57.1429 4 yes
GO:0080090 regulation of primary metabolic process 57.1429 4 yes
GO:0048522 positive regulation of cellular process 57.1429 4 no
GO:0031323 regulation of cellular metabolic process 55.3571 4 yes
GO:0051049 regulation of transport 51.7857 4 yes
GO:0048523 negative regulation of cellular process 50.0000 4 yes
GO:0051246 regulation of protein metabolic process 48.2143 5 yes
GO:0009966 regulation of signal transduction 39.2857 4 no
GO:0019220 regulation of phosphate metabolic process 37.5000 6 yes
GO:0051174 regulation of phosphorus metabolic process 37.5000 5 yes
GO:0006996 organelle organization 37.5000 4 no
GO:0031399 regulation of protein modification process 35.7143 6 yes
GO:0060341 regulation of cellular localization 35.7143 4 no
GO:0009893 positive regulation of metabolic process 35.7143 4 no
GO:0051128 regulation of cellular component organization 35.7143 4 no
GO:0022607 cellular component assembly 35.7143 4 no
GO:0006796 phosphate-containing compound metabolic process 33.9286 4 yes
GO:0051050 positive regulation of transport 33.9286 4 no
GO:0071310 cellular response to organic substance 33.9286 4 no
GO:0036211 protein modification process 32.1429 4 yes
GO:0042325 regulation of phosphorylation 32.1429 7 yes
GO:0043412 macromolecule modification 32.1429 4 yes
GO:0050804 modulation of chemical synaptic transmission 32.1429 5 yes
GO:0099177 regulation of trans-synaptic signaling 32.1429 4 yes
GO:0010647 positive regulation of cell communication 32.1429 5 no
GO:0023056 positive regulation of signaling 32.1429 4 no
GO:0010604 positive regulation of macromolecule metabolic process 32.1429 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 32.1429 5 no
GO:0008104 protein localization 30.3571 4 no
GO:0010468 regulation of gene expression 30.3571 5 no
GO:0051247 positive regulation of protein metabolic process 30.3571 6 no
GO:0001932 regulation of protein phosphorylation 28.5714 7 yes
GO:0060627 regulation of vesicle-mediated transport 28.5714 4 yes
GO:0032880 regulation of protein localization 28.5714 5 no
GO:0010243 response to organonitrogen compound 28.5714 4 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:1902531 regulation of intracellular signal transduction 28.5714 5 no
GO:0051338 regulation of transferase activity 26.7857 4 yes
GO:0043933 protein-containing complex organization 26.7857 4 no
GO:0048584 positive regulation of response to stimulus 26.7857 4 no
GO:0006468 protein phosphorylation 25.0000 5 yes
GO:0009892 negative regulation of metabolic process 25.0000 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 yes
GO:0016310 phosphorylation 25.0000 5 yes
GO:0016192 vesicle-mediated transport 25.0000 4 no
GO:0051130 positive regulation of cellular component organization 25.0000 5 no
GO:1901701 cellular response to oxygen-containing compound 25.0000 4 no
GO:0009889 regulation of biosynthetic process 25.0000 4 no
GO:0010556 regulation of macromolecule biosynthetic process 25.0000 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 25.0000 5 no
GO:0031324 negative regulation of cellular metabolic process 23.2143 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 23.2143 5 yes
GO:0030030 cell projection organization 23.2143 4 no
GO:1903829 positive regulation of protein localization 23.2143 5 no
GO:0033043 regulation of organelle organization 23.2143 5 no
GO:0080134 regulation of response to stress 23.2143 4 no
GO:0065003 protein-containing complex assembly 23.2143 5 no
GO:0010562 positive regulation of phosphorus metabolic process 23.2143 6 no
GO:0014070 response to organic cyclic compound 23.2143 4 no
GO:0045937 positive regulation of phosphate metabolic process 23.2143 7 no
GO:0009894 regulation of catabolic process 23.2143 4 no
GO:0043085 positive regulation of catalytic activity 23.2143 4 no
GO:0043549 regulation of kinase activity 21.4286 5 yes
GO:0009967 positive regulation of signal transduction 21.4286 5 no
GO:0010648 negative regulation of cell communication 21.4286 5 no
GO:0023057 negative regulation of signaling 21.4286 4 no
GO:0031401 positive regulation of protein modification process 21.4286 7 no
GO:0042327 positive regulation of phosphorylation 21.4286 8 no
GO:0071417 cellular response to organonitrogen compound 21.4286 4 no
GO:1901699 cellular response to nitrogen compound 21.4286 4 no
GO:0006355 regulation of DNA-templated transcription 21.4286 6 no
GO:0051252 regulation of RNA metabolic process 21.4286 5 no
GO:1903506 regulation of nucleic acid-templated transcription 21.4286 7 no
GO:2001141 regulation of RNA biosynthetic process 21.4286 6 no
GO:0043086 negative regulation of catalytic activity 19.6429 4 yes
GO:0045859 regulation of protein kinase activity 17.8571 6 yes
GO:0050890 cognition 17.8571 4 yes
GO:0051248 negative regulation of protein metabolic process 16.0714 6 yes
GO:0010563 negative regulation of phosphorus metabolic process 12.5000 6 yes
GO:0031400 negative regulation of protein modification process 12.5000 7 yes
GO:0045936 negative regulation of phosphate metabolic process 12.5000 7 yes
GO:0051348 negative regulation of transferase activity 10.7143 5 yes
GO:0071900 regulation of protein serine/threonine kinase activity 10.7143 7 yes
GO:2000479 regulation of cAMP-dependent protein kinase activity 10.7143 8 yes
GO:0001933 negative regulation of protein phosphorylation 8.9286 8 yes
GO:0006469 negative regulation of protein kinase activity 8.9286 7 yes
GO:0033673 negative regulation of kinase activity 8.9286 6 yes
GO:0042326 negative regulation of phosphorylation 8.9286 8 yes
GO:0071901 negative regulation of protein serine/threonine kinase activity 8.9286 8 yes
GO:2000480 negative regulation of cAMP-dependent protein kinase activity 8.9286 9 yes
GO:0098693 regulation of synaptic vesicle cycle 3.5714 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in KAP1_HUMAN
DOID:0050700 cardiomyopathy 3.5714 4 no
DOID:0060036 intrinsic cardiomyopathy 3.5714 5 no
DOID:114 heart disease 3.5714 3 no
DOID:331 central nervous system disease 3.5714 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
KAP0_HUMAN [view entry] [view interactions] Low throughput yes yes
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
AKAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
KAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
SCOT1_HUMAN [view entry] [view interactions] High throughput yes yes
IGHM_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
SNAG_HUMAN [view entry] [view interactions] High throughput yes yes
CF141_HUMAN [view interactions] High throughput no no
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
KAP3_HUMAN [view entry] [view interactions] High throughput yes yes
KAPCG_HUMAN [view interactions] High throughput no no
ERMAP_HUMAN [view interactions] High throughput no yes
SKP2_HUMAN [view interactions] High throughput no yes
MLF1_HUMAN [view entry] [view interactions] High throughput yes yes
RT15_HUMAN [view interactions] High throughput no yes
SFRP4_HUMAN [view interactions] High throughput no no
GP161_HUMAN [view interactions] High throughput no yes
KPRB_HUMAN [view interactions] High throughput no yes
H10_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
NUAK1_HUMAN [view interactions] High throughput no no
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
S30BP_HUMAN [view interactions] High throughput no yes
SHC3_HUMAN [view interactions] High throughput no yes
GNL3L_HUMAN [view interactions] High throughput no yes
GLIS2_HUMAN [view interactions] High throughput no no
LENG1_HUMAN [view interactions] High throughput no no
GPKOW_HUMAN [view interactions] High throughput no yes
ZNF35_HUMAN [view interactions] High throughput no no
SMG9_HUMAN [view interactions] High throughput no yes
CDN1A_HUMAN [view interactions] High throughput no no
ZN329_HUMAN [view interactions] High throughput no no
SH24A_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
RARG_HUMAN [view interactions] High throughput no yes
DPOE4_HUMAN [view interactions] High throughput no no
P55G_HUMAN [view interactions] High throughput no yes
GA2L2_HUMAN [view interactions] High throughput no no
LMBL2_HUMAN [view interactions] High throughput no no
F161A_HUMAN [view interactions] High throughput no no
AKA28_HUMAN [view interactions] High throughput no no
CC103_HUMAN [view interactions] High throughput no no
EF2KT_HUMAN [view interactions] High throughput no no
BD1L2_HUMAN [view interactions] High throughput no no
VEZF1_HUMAN [view interactions] High throughput no yes
PRP18_HUMAN [view interactions] High throughput no yes
AAPK2_HUMAN [view interactions] High throughput no yes
SYTL4_HUMAN [view interactions] High throughput no yes
ZNF76_HUMAN [view interactions] High throughput no no
THA_HUMAN [view interactions] High throughput no yes
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
F90A1_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
T10IP_HUMAN [view interactions] High throughput no no
COX5B_HUMAN [view entry] [view interactions] High throughput yes yes
UACA_HUMAN [view interactions] High throughput no yes
CBX8_HUMAN [view interactions] High throughput no yes
NTAQ1_HUMAN [view interactions] High throughput no yes
ZMY19_HUMAN [view interactions] High throughput no yes
QRIC1_HUMAN [view interactions] High throughput no yes
KANK2_HUMAN [view entry] [view interactions] High throughput yes yes
PSMG1_HUMAN [view interactions] High throughput no yes
LNX1_HUMAN [view interactions] High throughput no yes
STK16_HUMAN [view interactions] High throughput no no
ZBT16_HUMAN [view interactions] High throughput no yes
TEAD4_HUMAN [view interactions] High throughput no no
CEP19_HUMAN [view interactions] High throughput no no
GOGA1_HUMAN [view interactions] High throughput no yes
KINH_HUMAN [view entry] [view interactions] High throughput yes no
TASO2_HUMAN [view interactions] High throughput no yes
NXF1_HUMAN [view interactions] High throughput no yes
GUC1A_HUMAN [view interactions] High throughput no no
PI5PA_HUMAN [view interactions] High throughput no no
UBC9_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
CLUS_HUMAN [view entry] [view interactions] High throughput yes yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
WNK1_HUMAN [view entry] [view interactions] High throughput yes no
ANS1A_HUMAN [view interactions] High throughput no yes
MBD3_HUMAN [view interactions] High throughput no yes
MTG8_HUMAN [view interactions] High throughput no yes
ZN410_HUMAN [view interactions] High throughput no no
CAMP1_HUMAN [view interactions] High throughput no yes
FCSD2_HUMAN [view interactions] High throughput no no
DTNB_HUMAN [view entry] [view interactions] High throughput yes no
MED8_HUMAN [view interactions] High throughput no yes
IGFN1_HUMAN [view interactions] High throughput no no
ZN177_HUMAN [view interactions] High throughput no no
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
DACH1_HUMAN [view interactions] High throughput no no
PGTB2_HUMAN [view interactions] High throughput no yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
SYT11_HUMAN [view entry] [view interactions] High throughput yes yes
DCR1C_HUMAN [view interactions] High throughput no no
LNX2_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
NOX5_HUMAN [view interactions] High throughput no no
RPGF5_HUMAN [view interactions] High throughput no yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
FACD2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
DDX58_HUMAN [view interactions] High throughput no yes
TBB8_HUMAN [view interactions] High throughput no no
TALD3_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
MAP10_HUMAN [view interactions] High throughput no no
CCD96_HUMAN [view interactions] High throughput no no
GSK3A_HUMAN [view interactions] High throughput no yes
GATB_HUMAN [view interactions] High throughput no yes
GREB1_HUMAN [view interactions] High throughput no yes
FA43A_HUMAN [view interactions] High throughput no no
PREX2_HUMAN [view interactions] High throughput no no
DOXA2_HUMAN [view interactions] High throughput no no
CEP43_HUMAN [view interactions] High throughput no no
BMP1_HUMAN [view interactions] High throughput no yes
DJC13_HUMAN [view entry] [view interactions] High throughput yes yes
DUS16_HUMAN [view interactions] High throughput no yes
FLIP1_HUMAN [view entry] [view interactions] High throughput yes no
BCAT1_HUMAN [view interactions] High throughput no no
FRMD1_HUMAN [view interactions] High throughput no no
PLD1_HUMAN [view interactions] High throughput no no
SULF2_HUMAN [view interactions] High throughput no yes
RAI14_HUMAN [view interactions] High throughput no yes
AASD1_HUMAN [view interactions] High throughput no yes
ZN564_HUMAN [view interactions] High throughput no no
ZN507_HUMAN [view interactions] High throughput no no
IQCF2_HUMAN [view interactions] High throughput no no
IMDH1_HUMAN [view interactions] High throughput no yes
TIMP3_HUMAN [view interactions] High throughput no no
AKA11_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
FGF11_HUMAN [view interactions] High throughput no no
TFDP3_HUMAN [view interactions] High throughput no no
KLH28_HUMAN [view interactions] High throughput no no
SENP3_HUMAN [view interactions] High throughput no yes
MCM5_HUMAN [view interactions] High throughput no no
PIGH_HUMAN [view interactions] High throughput no yes
LGMN_HUMAN [view interactions] High throughput no yes
MYH7_HUMAN [view interactions] High throughput no no
MYH8_HUMAN [view interactions] High throughput no no
ETFA_HUMAN [view interactions] High throughput no yes
AT1A4_HUMAN [view entry] [view interactions] High throughput yes no
CQ078_HUMAN [view interactions] High throughput no no
CCD32_HUMAN [view interactions] High throughput no yes
ZN623_HUMAN [view interactions] High throughput no no
DYR1A_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
ZN749_HUMAN [view interactions] High throughput no no
CALU_HUMAN [view interactions] High throughput no yes
DUS3L_HUMAN [view interactions] High throughput no yes
EF2K_HUMAN [view entry] [view interactions] High throughput yes no
THG1_HUMAN [view interactions] High throughput no yes
DCAF7_HUMAN [view interactions] High throughput no yes
AKAP9_HUMAN [view entry] [view interactions] High throughput yes yes
NXPE4_HUMAN [view interactions] High throughput no no
SMAD4_HUMAN [view interactions] High throughput no yes
THRB_HUMAN [view interactions] Computational no no
ADCY4_HUMAN [view interactions] Computational no yes
CCL11_HUMAN [view interactions] Computational no no
STMN1_HUMAN [view interactions] Computational no yes
EZRI_HUMAN [view entry] [view interactions] Computational yes no
PRKX_HUMAN [view interactions] Computational no yes
CFTR_HUMAN [view interactions] Computational no no
B2CL1_HUMAN [view interactions] Computational no yes
ADCY9_HUMAN [view interactions] Computational no yes
LIPS_HUMAN [view entry] [view interactions] Computational yes no
EDN1_HUMAN [view interactions] Computational no no
SDF1_HUMAN [view interactions] Computational no no
GNAS1_HUMAN [view entry] [view interactions] Computational yes yes
ITA1_HUMAN [view interactions] Computational no yes
CSK_HUMAN [view interactions] Computational no yes
PAXI_HUMAN [view interactions] Computational no yes
CCL4_HUMAN [view interactions] Computational no no
MLXPL_HUMAN [view interactions] Computational no no
ITB1_HUMAN [view entry] [view interactions] Computational yes no
NHRF1_HUMAN [view interactions] Computational no no
MLC1_HUMAN [view interactions] Computational no no
BCL2_HUMAN [view interactions] Computational no no
AKAP5_HUMAN [view entry] [view interactions] Computational yes yes
ADRB2_HUMAN [view entry] [view interactions] Computational yes no
ANGT_HUMAN [view interactions] Computational no no
ADCY7_HUMAN [view interactions] Computational no yes
ADCY6_HUMAN [view interactions] Computational no yes
CD2_HUMAN [view interactions] Computational no no
ADCY8_HUMAN [view entry] [view interactions] Computational yes yes
FINC_HUMAN [view interactions] Computational no yes
KAP2_HUMAN [view entry] [view interactions] Computational yes yes
GBG1_HUMAN [view interactions] Computational no no
ADCY1_HUMAN [view entry] [view interactions] Computational yes no
2A5D_HUMAN [view entry] [view interactions] Computational yes yes
PPR1B_HUMAN [view entry] [view interactions] Computational yes yes
TLN1_HUMAN [view entry] [view interactions] Computational yes no
ITA4_HUMAN [view interactions] Computational no no
CREB1_HUMAN [view interactions] Computational no yes
MK03_HUMAN [view entry] [view interactions] Computational yes yes
GBB1_HUMAN [view entry] [view interactions] Computational yes yes
MPIP3_HUMAN [view interactions] Computational no yes
NOS1_HUMAN [view entry] [view interactions] Computational yes yes
FAK1_HUMAN [view entry] [view interactions] Computational yes yes
ADCY2_HUMAN [view interactions] Computational no yes
BAD_HUMAN [view entry] [view interactions] Computational yes yes
MK01_HUMAN [view entry] [view interactions] Computational yes yes
CD3Z_HUMAN [view interactions] Computational no no
CREM_HUMAN [view interactions] Computational no no