Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NDUAA_HUMAN

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in NDUAA_HUMAN
GO:0008324 monoatomic cation transmembrane transporter activity 33.3333 4 yes
GO:0015078 proton transmembrane transporter activity 33.3333 5 yes
GO:0015399 primary active transmembrane transporter activity 33.3333 4 yes
GO:0015453 oxidoreduction-driven active transmembrane transporter activity 33.3333 5 yes
GO:0022853 active monoatomic ion transmembrane transporter activity 33.3333 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 33.3333 4 yes
GO:0043169 cation binding 28.5714 4 no
GO:0046872 metal ion binding 28.5714 5 no
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 26.1905 4 yes
GO:0000166 nucleotide binding 26.1905 4 no
GO:0017076 purine nucleotide binding 23.8095 5 no
GO:0043168 anion binding 23.8095 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in NDUAA_HUMAN
GO:0006796 phosphate-containing compound metabolic process 47.6190 4 yes
GO:0015980 energy derivation by oxidation of organic compounds 41.6667 4 yes
GO:0009060 aerobic respiration 40.4762 6 yes
GO:0022607 cellular component assembly 40.4762 4 yes
GO:0045333 cellular respiration 40.4762 5 yes
GO:0022900 electron transport chain 39.2857 4 yes
GO:0022904 respiratory electron transport chain 39.2857 5 yes
GO:0006753 nucleoside phosphate metabolic process 36.9048 4 yes
GO:0009117 nucleotide metabolic process 36.9048 5 yes
GO:0019646 aerobic electron transport chain 36.9048 6 yes
GO:0006163 purine nucleotide metabolic process 35.7143 5 yes
GO:0072521 purine-containing compound metabolic process 35.7143 4 yes
GO:1901566 organonitrogen compound biosynthetic process 35.7143 4 yes
GO:0009150 purine ribonucleotide metabolic process 33.3333 6 yes
GO:0009259 ribonucleotide metabolic process 33.3333 5 yes
GO:0019693 ribose phosphate metabolic process 33.3333 4 yes
GO:1901362 organic cyclic compound biosynthetic process 33.3333 4 yes
GO:0034654 nucleobase-containing compound biosynthetic process 30.9524 4 yes
GO:0043933 protein-containing complex organization 30.9524 4 yes
GO:0090407 organophosphate biosynthetic process 30.9524 4 yes
GO:0031323 regulation of cellular metabolic process 30.9524 4 no
GO:0006164 purine nucleotide biosynthetic process 29.7619 6 yes
GO:0009152 purine ribonucleotide biosynthetic process 29.7619 7 yes
GO:0009165 nucleotide biosynthetic process 29.7619 6 yes
GO:0009260 ribonucleotide biosynthetic process 29.7619 6 yes
GO:0046390 ribose phosphate biosynthetic process 29.7619 5 yes
GO:0072522 purine-containing compound biosynthetic process 29.7619 5 yes
GO:1901137 carbohydrate derivative biosynthetic process 29.7619 4 yes
GO:1901293 nucleoside phosphate biosynthetic process 29.7619 5 yes
GO:0065003 protein-containing complex assembly 27.3810 5 yes
GO:0048522 positive regulation of cellular process 27.3810 4 no
GO:0060255 regulation of macromolecule metabolic process 27.3810 4 no
GO:0080090 regulation of primary metabolic process 27.3810 4 no
GO:0010646 regulation of cell communication 26.1905 4 no
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 25.0000 7 yes
GO:0006754 ATP biosynthetic process 25.0000 8 yes
GO:0009141 nucleoside triphosphate metabolic process 25.0000 5 yes
GO:0009142 nucleoside triphosphate biosynthetic process 25.0000 6 yes
GO:0009144 purine nucleoside triphosphate metabolic process 25.0000 6 yes
GO:0009145 purine nucleoside triphosphate biosynthetic process 25.0000 7 yes
GO:0009199 ribonucleoside triphosphate metabolic process 25.0000 6 yes
GO:0009201 ribonucleoside triphosphate biosynthetic process 25.0000 7 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 25.0000 7 yes
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 25.0000 8 yes
GO:0015986 proton motive force-driven ATP synthesis 25.0000 9 yes
GO:0042776 proton motive force-driven mitochondrial ATP synthesis 25.0000 10 yes
GO:0046034 ATP metabolic process 25.0000 7 yes
GO:0006996 organelle organization 25.0000 4 no
GO:0009966 regulation of signal transduction 23.8095 4 no
GO:0048523 negative regulation of cellular process 23.8095 4 no
GO:0009893 positive regulation of metabolic process 22.6190 4 no
GO:0033108 mitochondrial respiratory chain complex assembly 21.4286 6 yes
GO:0051128 regulation of cellular component organization 21.4286 4 no
GO:0019752 carboxylic acid metabolic process 21.4286 5 no
GO:0043436 oxoacid metabolic process 21.4286 4 no
GO:0010257 NADH dehydrogenase complex assembly 20.2381 6 yes
GO:0032981 mitochondrial respiratory chain complex I assembly 20.2381 7 yes
GO:0009889 regulation of biosynthetic process 20.2381 4 no
GO:0010468 regulation of gene expression 20.2381 6 no
GO:0010556 regulation of macromolecule biosynthetic process 20.2381 5 no
GO:0010604 positive regulation of macromolecule metabolic process 20.2381 5 no
GO:0031326 regulation of cellular biosynthetic process 20.2381 5 no
GO:0048584 positive regulation of response to stimulus 20.2381 4 no
GO:0051246 regulation of protein metabolic process 20.2381 5 no

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NU4LM_HUMAN [view interactions] Low throughput no no
NDUB1_HUMAN [view interactions] Low throughput no yes
NDUB8_HUMAN [view entry] [view interactions] Low throughput yes yes
NU4M_HUMAN [view interactions] Low throughput no yes
NDUB2_HUMAN [view interactions] Low throughput no yes
NDUAD_HUMAN [view entry] [view interactions] Low throughput yes yes
NU1M_HUMAN [view interactions] Low throughput no yes
NU5M_HUMAN [view interactions] Low throughput no no
NDUAB_HUMAN [view interactions] Low throughput no no
ACPM_HUMAN [view interactions] Low throughput no yes
NDUBB_HUMAN [view interactions] Low throughput no yes
NDUB7_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUC2_HUMAN [view interactions] Low throughput no yes
NDUB3_HUMAN [view interactions] Low throughput no yes
NDUA1_HUMAN [view interactions] Low throughput no yes
NDUS2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA3_HUMAN [view interactions] Low throughput no yes
NDUA8_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUBA_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUB4_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS5_HUMAN [view interactions] Low throughput no yes
NDUB6_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUB5_HUMAN [view interactions] Low throughput no yes
NU3M_HUMAN [view interactions] Low throughput no yes
NDUB9_HUMAN [view entry] [view interactions] Low throughput yes yes
NU6M_HUMAN [view interactions] Low throughput no no
NDUC1_HUMAN [view interactions] Low throughput no yes
NU2M_HUMAN [view interactions] Low throughput no no
BRCC3_HUMAN [view interactions] High throughput no no
WIPI2_HUMAN [view interactions] High throughput no yes
HDA11_HUMAN [view interactions] High throughput no no
RIPK4_HUMAN [view interactions] High throughput no no
NDUA9_HUMAN [view entry] [view interactions] High throughput yes yes
PLK1_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RMD3_HUMAN [view entry] [view interactions] High throughput yes yes
MDEAS_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
GOT1B_HUMAN [view interactions] High throughput no yes
CLU_HUMAN [view interactions] High throughput no yes
IF2M_HUMAN [view interactions] High throughput no yes
DECR_HUMAN [view entry] [view interactions] High throughput yes yes
CLPP_HUMAN [view interactions] High throughput no yes
NDUF5_HUMAN [view interactions] High throughput no yes
ACD10_HUMAN [view interactions] High throughput no no
KDM1B_HUMAN [view interactions] High throughput no yes
RSPRY_HUMAN [view interactions] High throughput no yes
DHRS4_HUMAN [view entry] [view interactions] High throughput yes no
SIR3_HUMAN [view interactions] High throughput no yes
NMES1_HUMAN [view interactions] High throughput no no
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
PTPM1_HUMAN [view interactions] High throughput no yes
SPT20_HUMAN [view interactions] High throughput no yes
MP2K1_HUMAN [view entry] [view interactions] High throughput yes yes
SOAT1_HUMAN [view interactions] High throughput no no
NDUA5_HUMAN [view entry] [view interactions] High throughput yes yes
SAT2_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
ZAP70_HUMAN [view interactions] High throughput no no
STA5B_HUMAN [view interactions] High throughput no yes
NEP_HUMAN [view interactions] High throughput no no
NDUA6_HUMAN [view interactions] High throughput no no
HSC20_HUMAN [view interactions] High throughput no yes
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
KCNQ1_HUMAN [view interactions] High throughput no yes
CAV3_HUMAN [view interactions] High throughput no no
EGLN_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
RYBP_HUMAN [view interactions] High throughput no no
NFKB1_HUMAN [view interactions] High throughput no yes
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
ESR1_HUMAN [view interactions] High throughput no no
LCOR_HUMAN [view interactions] High throughput no yes
DSCR9_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
PCNA_HUMAN [view interactions] High throughput no no
NDUA2_HUMAN [view entry] [view interactions] High throughput yes yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
FHI2B_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
MDC1_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
LGR4_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
RN123_HUMAN [view interactions] High throughput no yes
PXDC2_HUMAN [view interactions] High throughput no yes
NDUF7_HUMAN [view interactions] High throughput no yes
BCKD_HUMAN [view entry] [view interactions] High throughput yes yes
PPOX_HUMAN [view interactions] High throughput no no
B3GN2_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
DCX_HUMAN [view entry] [view interactions] High throughput yes yes
BMR1A_HUMAN [view interactions] High throughput no no
EGLN3_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
FXRD1_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
PRC1_HUMAN [view interactions] High throughput no yes
MD2L2_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
RNF5_HUMAN [view interactions] High throughput no yes
SYLM_HUMAN [view interactions] High throughput no yes
NDUV2_HUMAN [view entry] [view interactions] High throughput yes yes
NDUV3_HUMAN [view interactions] High throughput no yes
AURKA_HUMAN [view entry] [view interactions] High throughput yes no
SPSB4_HUMAN [view interactions] High throughput no no
NDUS7_HUMAN [view entry] [view interactions] High throughput yes no
TRI43_HUMAN [view interactions] High throughput no no
AMACR_HUMAN [view interactions] High throughput no yes
NDUA7_HUMAN [view entry] [view interactions] High throughput yes yes
GATA_HUMAN [view interactions] High throughput no yes
MRM2_HUMAN [view interactions] High throughput no yes
DJC30_HUMAN [view interactions] High throughput no no
FAHD1_HUMAN [view interactions] High throughput no yes
NDUS6_HUMAN [view entry] [view interactions] High throughput yes yes
SPRTN_HUMAN [view interactions] High throughput no yes
WIPI1_HUMAN [view interactions] High throughput no yes
FSCN1_HUMAN [view entry] [view interactions] High throughput yes yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
BRD4_HUMAN [view interactions] High throughput no yes
RHOF_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOD_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RND2_HUMAN [view interactions] High throughput no no
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
TLS1_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ACE2_HUMAN [view interactions] High throughput no no
GBRA1_HUMAN [view entry] [view interactions] High throughput yes yes
PARPT_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
VIGLN_HUMAN [view entry] [view interactions] High throughput yes yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
ASXL1_HUMAN [view interactions] High throughput no no
ASXL2_HUMAN [view interactions] High throughput no no
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
UBP48_HUMAN [view interactions] High throughput no yes
PJA2_HUMAN [view entry] [view interactions] High throughput yes yes
MIDN_HUMAN [view interactions] High throughput no no
SMC5_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
OTUD1_HUMAN [view interactions] High throughput no yes
MPV17_HUMAN [view interactions] High throughput no no
SDHB_HUMAN [view interactions] High throughput no yes
MRP2_HUMAN [view interactions] High throughput no no
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
COX5B_HUMAN [view entry] [view interactions] High throughput yes yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
NDUAC_HUMAN [view entry] [view interactions] High throughput yes yes
NDUV1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR7_HUMAN [view entry] [view interactions] High throughput yes yes
QCR8_HUMAN [view interactions] High throughput no yes
ATP5H_HUMAN [view interactions] High throughput no yes
ATPA_HUMAN [view interactions] High throughput no yes
ATPB_HUMAN [view interactions] High throughput no yes
BOLA3_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
MIC26_HUMAN [view entry] [view interactions] High throughput yes yes
ATPD_HUMAN [view interactions] High throughput no yes
AT5F1_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no no
DNJB4_HUMAN [view entry] [view interactions] High throughput yes yes
ECHD1_HUMAN [view interactions] High throughput no no
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
ATPG_HUMAN [view interactions] High throughput no yes
ATP5I_HUMAN [view interactions] High throughput no yes
ATPK_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
COQ9_HUMAN [view interactions] High throughput no yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
FUMH_HUMAN [view entry] [view interactions] High throughput yes yes
AATM_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3G_HUMAN [view entry] [view interactions] High throughput yes yes
LDHB_HUMAN [view entry] [view interactions] High throughput yes yes
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS1_HUMAN [view entry] [view interactions] High throughput yes no
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
NDUCR_HUMAN [view interactions] High throughput no yes
NDUS4_HUMAN [view interactions] High throughput no yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
M2OM_HUMAN [view entry] [view interactions] High throughput yes yes
SUCB1_HUMAN [view entry] [view interactions] High throughput yes yes
SUCA_HUMAN [view entry] [view interactions] High throughput yes yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
UCRI_HUMAN [view entry] [view interactions] High throughput yes yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
QCR9_HUMAN [view interactions] High throughput no no
ASB2_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
SYAM_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
BROMI_HUMAN [view interactions] High throughput no no
TAXB1_HUMAN [view interactions] High throughput no yes
KAP1_HUMAN [view entry] [view interactions] High throughput yes yes
KDM1A_HUMAN [view interactions] High throughput no yes
HDAC1_HUMAN [view interactions] High throughput no no
PF21A_HUMAN [view interactions] High throughput no yes
RCOR1_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes