Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NDUA5_HUMAN

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in NDUA5_HUMAN
GO:0008324 monoatomic cation transmembrane transporter activity 29.0323 4 yes
GO:0015078 proton transmembrane transporter activity 29.0323 5 yes
GO:0022853 active monoatomic ion transmembrane transporter activity 29.0323 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 29.0323 4 yes
GO:0043169 cation binding 29.0323 4 no
GO:0015399 primary active transmembrane transporter activity 27.9570 4 yes
GO:0000166 nucleotide binding 27.9570 4 no
GO:0015453 oxidoreduction-driven active transmembrane transporter activity 26.8817 5 yes
GO:0017076 purine nucleotide binding 25.8065 5 no
GO:0043168 anion binding 25.8065 4 no
GO:0046872 metal ion binding 25.8065 5 no
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 23.6559 4 yes
GO:0032555 purine ribonucleotide binding 21.5054 4 no
GO:0035639 purine ribonucleoside triphosphate binding 21.5054 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in NDUA5_HUMAN
GO:0022607 cellular component assembly 43.0108 4 yes
GO:0006796 phosphate-containing compound metabolic process 33.3333 4 yes
GO:0043933 protein-containing complex organization 33.3333 4 yes
GO:0009060 aerobic respiration 32.2581 6 yes
GO:0015980 energy derivation by oxidation of organic compounds 32.2581 4 yes
GO:0022900 electron transport chain 32.2581 4 yes
GO:0022904 respiratory electron transport chain 32.2581 5 yes
GO:0045333 cellular respiration 32.2581 5 yes
GO:0006996 organelle organization 32.2581 4 no
GO:0065003 protein-containing complex assembly 31.1828 5 yes
GO:0031323 regulation of cellular metabolic process 31.1828 4 no
GO:0006753 nucleoside phosphate metabolic process 30.1075 4 yes
GO:0009117 nucleotide metabolic process 30.1075 5 yes
GO:0048522 positive regulation of cellular process 30.1075 4 no
GO:0006163 purine nucleotide metabolic process 29.0323 5 yes
GO:0019646 aerobic electron transport chain 29.0323 6 yes
GO:0072521 purine-containing compound metabolic process 29.0323 4 yes
GO:1901362 organic cyclic compound biosynthetic process 29.0323 4 yes
GO:0009150 purine ribonucleotide metabolic process 27.9570 6 yes
GO:0009259 ribonucleotide metabolic process 27.9570 5 yes
GO:0019693 ribose phosphate metabolic process 27.9570 4 yes
GO:0048523 negative regulation of cellular process 27.9570 4 no
GO:0034654 nucleobase-containing compound biosynthetic process 26.8817 4 yes
GO:1901566 organonitrogen compound biosynthetic process 26.8817 4 yes
GO:0080090 regulation of primary metabolic process 26.8817 4 no
GO:0060255 regulation of macromolecule metabolic process 25.8065 4 no
GO:0051128 regulation of cellular component organization 25.8065 4 no
GO:0090407 organophosphate biosynthetic process 24.7312 4 yes
GO:0006164 purine nucleotide biosynthetic process 23.6559 6 yes
GO:0009141 nucleoside triphosphate metabolic process 23.6559 5 yes
GO:0009144 purine nucleoside triphosphate metabolic process 23.6559 6 yes
GO:0009152 purine ribonucleotide biosynthetic process 23.6559 7 yes
GO:0009165 nucleotide biosynthetic process 23.6559 6 yes
GO:0009199 ribonucleoside triphosphate metabolic process 23.6559 6 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 23.6559 7 yes
GO:0009260 ribonucleotide biosynthetic process 23.6559 6 yes
GO:0046034 ATP metabolic process 23.6559 7 yes
GO:0046390 ribose phosphate biosynthetic process 23.6559 5 yes
GO:0072522 purine-containing compound biosynthetic process 23.6559 5 yes
GO:1901137 carbohydrate derivative biosynthetic process 23.6559 4 yes
GO:1901293 nucleoside phosphate biosynthetic process 23.6559 5 yes
GO:0009893 positive regulation of metabolic process 23.6559 4 no
GO:0010646 regulation of cell communication 22.5806 4 no
GO:0006754 ATP biosynthetic process 21.5054 8 yes
GO:0009142 nucleoside triphosphate biosynthetic process 21.5054 6 yes
GO:0009145 purine nucleoside triphosphate biosynthetic process 21.5054 7 yes
GO:0009201 ribonucleoside triphosphate biosynthetic process 21.5054 7 yes
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 21.5054 8 yes
GO:0015986 proton motive force-driven ATP synthesis 21.5054 9 yes
GO:0042776 proton motive force-driven mitochondrial ATP synthesis 21.5054 10 yes
GO:0008104 protein localization 21.5054 4 no
GO:0071702 organic substance transport 21.5054 4 no
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 20.4301 7 yes
GO:0033108 mitochondrial respiratory chain complex assembly 20.4301 6 yes
GO:0010604 positive regulation of macromolecule metabolic process 20.4301 5 no
GO:0051246 regulation of protein metabolic process 20.4301 5 no
GO:0071705 nitrogen compound transport 20.4301 4 no
GO:0009966 regulation of signal transduction 20.4301 4 no
GO:0010257 NADH dehydrogenase complex assembly 18.2796 6 yes
GO:0032981 mitochondrial respiratory chain complex I assembly 18.2796 7 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NDUS1_HUMAN [view entry] [view interactions] Low throughput yes no
NDUS8_HUMAN [view interactions] Low throughput no yes
NDUS2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV1_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS4_HUMAN [view interactions] Low throughput no yes
NDUV2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUAC_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS3_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS7_HUMAN [view entry] [view interactions] Low throughput yes no
NDUA9_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUAD_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA7_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA6_HUMAN [view interactions] Low throughput no no
NDUA2_HUMAN [view entry] [view interactions] Low throughput yes yes
ACPM_HUMAN [view interactions] Low throughput no yes
NDUV3_HUMAN [view interactions] Low throughput no yes
NDUS6_HUMAN [view entry] [view interactions] Low throughput yes yes
UBE2H_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
GCN1_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
SCMC1_HUMAN [view interactions] High throughput no no
RCN2_HUMAN [view interactions] High throughput no yes
ATP5H_HUMAN [view interactions] High throughput no yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
CYB5_HUMAN [view interactions] High throughput no no
COX6C_HUMAN [view entry] [view interactions] High throughput yes yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
ATPO_HUMAN [view interactions] High throughput no yes
VATB2_HUMAN [view entry] [view interactions] High throughput yes yes
CX6A1_HUMAN [view interactions] High throughput no yes
ECHB_HUMAN [view entry] [view interactions] High throughput yes yes
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
MCCB_HUMAN [view entry] [view interactions] High throughput yes yes
MTCH2_HUMAN [view entry] [view interactions] High throughput yes yes
TOM5_HUMAN [view interactions] High throughput no yes
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
ATPD_HUMAN [view interactions] High throughput no yes
AT5F1_HUMAN [view interactions] High throughput no yes
AT5L2_HUMAN [view interactions] High throughput no no
ATP5L_HUMAN [view interactions] High throughput no yes
VATF_HUMAN [view interactions] High throughput no yes
MPC2_HUMAN [view interactions] High throughput no yes
NDUA3_HUMAN [view interactions] High throughput no yes
ATPA_HUMAN [view interactions] High throughput no yes
ATP5J_HUMAN [view interactions] High throughput no yes
QCR6L_HUMAN [view interactions] High throughput no yes
QCR6_HUMAN [view interactions] High throughput no yes
ATPMK_HUMAN [view interactions] High throughput no no
NDUB7_HUMAN [view entry] [view interactions] High throughput yes yes
NDUC2_HUMAN [view interactions] High throughput no yes
NDUCR_HUMAN [view interactions] High throughput no yes
SDHB_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5E_HUMAN [view interactions] High throughput no no
ATP5I_HUMAN [view interactions] High throughput no yes
ATPK_HUMAN [view interactions] High throughput no yes
BOLA2_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
ODP2_HUMAN [view entry] [view interactions] High throughput yes yes
C10_HUMAN [view interactions] High throughput no yes
HINT1_HUMAN [view interactions] High throughput no yes
NDUB6_HUMAN [view entry] [view interactions] High throughput yes yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
TIM10_HUMAN [view interactions] High throughput no yes
QCR9_HUMAN [view interactions] High throughput no no
NDUB4_HUMAN [view entry] [view interactions] High throughput yes yes
UCRI_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
CX7A2_HUMAN [view interactions] High throughput no no
IDH3G_HUMAN [view entry] [view interactions] High throughput yes yes
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
SUCB1_HUMAN [view entry] [view interactions] High throughput yes yes
MRM1_HUMAN [view interactions] High throughput no no
DPPA3_HUMAN [view interactions] High throughput no no
GRSF1_HUMAN [view interactions] High throughput no yes
ACAD9_HUMAN [view interactions] High throughput no yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
MTRFR_HUMAN [view interactions] High throughput no yes
CQ080_HUMAN [view interactions] High throughput no yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no no
MRES1_HUMAN [view interactions] High throughput no yes
CH082_HUMAN [view interactions] High throughput no yes
MCUR1_HUMAN [view interactions] High throughput no no
CC90B_HUMAN [view interactions] High throughput no yes
CHCH1_HUMAN [view interactions] High throughput no yes
CLPB_HUMAN [view interactions] High throughput no yes
QOR_HUMAN [view entry] [view interactions] High throughput yes yes
DDX28_HUMAN [view interactions] High throughput no yes
DHX30_HUMAN [view entry] [view interactions] High throughput yes yes
DBLOH_HUMAN [view interactions] High throughput no no
FAKD2_HUMAN [view interactions] High throughput no no
FAKD3_HUMAN [view interactions] High throughput no yes
FAKD5_HUMAN [view interactions] High throughput no yes
EFGM_HUMAN [view interactions] High throughput no yes
RRF2M_HUMAN [view interactions] High throughput no yes
HINT2_HUMAN [view interactions] High throughput no yes
ICT1_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
MCU_HUMAN [view interactions] High throughput no yes
MCUB_HUMAN [view interactions] High throughput no no
MET15_HUMAN [view interactions] High throughput no no
MET17_HUMAN [view interactions] High throughput no yes
MIC26_HUMAN [view entry] [view interactions] High throughput yes yes
RM11_HUMAN [view interactions] High throughput no yes
RT12_HUMAN [view interactions] High throughput no yes
RT26_HUMAN [view interactions] High throughput no yes
RRFM_HUMAN [view interactions] High throughput no yes
MTEF3_HUMAN [view interactions] High throughput no no
FMT_HUMAN [view interactions] High throughput no yes
MTG1_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
IF2M_HUMAN [view interactions] High throughput no yes
IF3M_HUMAN [view interactions] High throughput no yes
BABA1_HUMAN [view interactions] High throughput no yes
RF1M_HUMAN [view interactions] High throughput no yes
DMWD_HUMAN [view entry] [view interactions] High throughput yes no
RF1ML_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
NGRN_HUMAN [view interactions] High throughput no yes
OTC_HUMAN [view interactions] High throughput no no
MPPA_HUMAN [view interactions] High throughput no yes
NDUS5_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
RMND1_HUMAN [view interactions] High throughput no yes
RUSD3_HUMAN [view interactions] High throughput no yes
NDUAB_HUMAN [view interactions] High throughput no no
RUSD4_HUMAN [view interactions] High throughput no yes
S2512_HUMAN [view entry] [view interactions] High throughput yes yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
S2551_HUMAN [view interactions] High throughput no no
GOT1B_HUMAN [view interactions] High throughput no yes
SLIRP_HUMAN [view interactions] High throughput no yes
MD2L2_HUMAN [view interactions] High throughput no yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
NMES1_HUMAN [view interactions] High throughput no no
SURF1_HUMAN [view interactions] High throughput no yes
FMC1_HUMAN [view interactions] High throughput no no
TACO1_HUMAN [view interactions] High throughput no yes
COQ9_HUMAN [view interactions] High throughput no yes
FAKD4_HUMAN [view interactions] High throughput no yes
DHRS4_HUMAN [view entry] [view interactions] High throughput yes no
TEFM_HUMAN [view interactions] High throughput no no
NDUF4_HUMAN [view interactions] High throughput no yes
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
TIM29_HUMAN [view interactions] High throughput no no
MAIP1_HUMAN [view interactions] High throughput no yes
TMM70_HUMAN [view interactions] High throughput no yes
CISD3_HUMAN [view interactions] High throughput no yes
TRUB2_HUMAN [view interactions] High throughput no yes
NDUF8_HUMAN [view interactions] High throughput no no
EFTS_HUMAN [view interactions] High throughput no no
F136A_HUMAN [view interactions] High throughput no yes
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
CHC10_HUMAN [view interactions] High throughput no yes
VWA8_HUMAN [view interactions] High throughput no yes
NDKM_HUMAN [view interactions] High throughput no yes
EXD2_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
DJC15_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
TIM14_HUMAN [view entry] [view interactions] High throughput yes yes
TAGL_HUMAN [view interactions] High throughput no no
DJC28_HUMAN [view interactions] High throughput no yes
SIM26_HUMAN [view interactions] High throughput no no
DNJC4_HUMAN [view interactions] High throughput no yes
TMIG1_HUMAN [view interactions] High throughput no no
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
FINC_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
COX15_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
SOAT1_HUMAN [view interactions] High throughput no no
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
NDUAA_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
TR10A_HUMAN [view interactions] High throughput no no
KLF16_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
PKHF2_HUMAN [view interactions] High throughput no yes
TTHY_HUMAN [view interactions] High throughput no no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
KAT5_HUMAN [view interactions] High throughput no yes
DAZP2_HUMAN [view interactions] High throughput no no
NDUB1_HUMAN [view interactions] High throughput no yes
CC85B_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no
RAB32_HUMAN [view interactions] High throughput no yes
RAB8A_HUMAN [view entry] [view interactions] High throughput yes no
WDR26_HUMAN [view interactions] High throughput no yes
JMJD6_HUMAN [view interactions] High throughput no yes
TECT3_HUMAN [view interactions] High throughput no yes
CE128_HUMAN [view interactions] High throughput no yes
TECT2_HUMAN [view interactions] High throughput no yes
CE152_HUMAN [view interactions] High throughput no yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
AKIP_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
COX14_HUMAN [view interactions] High throughput no yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
PDK1_HUMAN [view interactions] High throughput no yes
SCO1_HUMAN [view interactions] High throughput no yes
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
TR61B_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
IMP1L_HUMAN [view interactions] High throughput no yes
PARL_HUMAN [view interactions] High throughput no yes
FHI1B_HUMAN [view interactions] High throughput no yes
FHI2B_HUMAN [view interactions] High throughput no yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
COG6_HUMAN [view interactions] High throughput no yes
CBY2_HUMAN [view interactions] High throughput no no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
ABCE1_HUMAN [view interactions] High throughput no yes
PO5F1_HUMAN [view interactions] High throughput no yes
OXDA_HUMAN [view interactions] High throughput no no
HDAC4_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
FXRD1_HUMAN [view interactions] High throughput no no
H4_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
LMBRL_HUMAN [view interactions] High throughput no no
RHG36_HUMAN [view interactions] High throughput no yes
AURKB_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
DNJA3_HUMAN [view entry] [view interactions] High throughput yes yes
DNJB8_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
M4K1_HUMAN [view interactions] High throughput no no
DJC30_HUMAN [view interactions] High throughput no no
TIDC1_HUMAN [view interactions] High throughput no yes
NDUB3_HUMAN [view interactions] High throughput no yes
NDUBB_HUMAN [view interactions] High throughput no yes
NDUA1_HUMAN [view interactions] High throughput no yes
NDUB5_HUMAN [view interactions] High throughput no yes
DPP4_HUMAN [view interactions] High throughput no no
TMPS4_HUMAN [view interactions] High throughput no yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOD_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
CBX1_HUMAN [view interactions] High throughput no yes
MYCN_HUMAN [view interactions] High throughput no no
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
RNF43_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
ASXL1_HUMAN [view interactions] High throughput no no
ASXL2_HUMAN [view interactions] High throughput no no
ASXL3_HUMAN [view interactions] High throughput no no
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
PJA2_HUMAN [view entry] [view interactions] High throughput yes yes
OTUL_HUMAN [view interactions] High throughput no yes
UBP11_HUMAN [view interactions] High throughput no yes
CL16A_HUMAN [view interactions] High throughput no yes