NDUB7_HUMAN
Evidence for PS localization
Functions
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NDUB7_HUMAN |
|---|---|---|---|---|
| GO:0008324 | monoatomic cation transmembrane transporter activity | 52.9412 | 4 | yes |
| GO:0015078 | proton transmembrane transporter activity | 52.9412 | 5 | yes |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 52.9412 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 52.9412 | 4 | yes |
| GO:0015399 | primary active transmembrane transporter activity | 50.9804 | 4 | yes |
| GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 49.0196 | 5 | yes |
| GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 41.1765 | 4 | yes |
| GO:0043169 | cation binding | 37.2549 | 4 | no |
| GO:0046872 | metal ion binding | 37.2549 | 5 | no |
| GO:0000166 | nucleotide binding | 21.5686 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NDUB7_HUMAN |
|---|---|---|---|---|
| GO:0015980 | energy derivation by oxidation of organic compounds | 58.8235 | 4 | yes |
| GO:0009060 | aerobic respiration | 56.8627 | 6 | yes |
| GO:0022900 | electron transport chain | 56.8627 | 4 | yes |
| GO:0022904 | respiratory electron transport chain | 56.8627 | 5 | yes |
| GO:0045333 | cellular respiration | 56.8627 | 5 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 54.9020 | 4 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 52.9412 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 52.9412 | 5 | yes |
| GO:0019646 | aerobic electron transport chain | 52.9412 | 6 | yes |
| GO:0006163 | purine nucleotide metabolic process | 50.9804 | 5 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 50.9804 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 50.9804 | 5 | yes |
| GO:0019693 | ribose phosphate metabolic process | 50.9804 | 4 | yes |
| GO:0072521 | purine-containing compound metabolic process | 50.9804 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 50.9804 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 50.9804 | 4 | yes |
| GO:0006164 | purine nucleotide biosynthetic process | 49.0196 | 6 | yes |
| GO:0009152 | purine ribonucleotide biosynthetic process | 49.0196 | 7 | yes |
| GO:0009165 | nucleotide biosynthetic process | 49.0196 | 6 | yes |
| GO:0009260 | ribonucleotide biosynthetic process | 49.0196 | 6 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 49.0196 | 4 | yes |
| GO:0046390 | ribose phosphate biosynthetic process | 49.0196 | 5 | yes |
| GO:0072522 | purine-containing compound biosynthetic process | 49.0196 | 5 | yes |
| GO:0090407 | organophosphate biosynthetic process | 49.0196 | 4 | yes |
| GO:1901137 | carbohydrate derivative biosynthetic process | 49.0196 | 4 | yes |
| GO:1901293 | nucleoside phosphate biosynthetic process | 49.0196 | 5 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 43.1373 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 43.1373 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 43.1373 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 43.1373 | 7 | yes |
| GO:0022607 | cellular component assembly | 43.1373 | 4 | yes |
| GO:0046034 | ATP metabolic process | 43.1373 | 7 | yes |
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | 41.1765 | 7 | yes |
| GO:0006754 | ATP biosynthetic process | 41.1765 | 8 | yes |
| GO:0009142 | nucleoside triphosphate biosynthetic process | 41.1765 | 6 | yes |
| GO:0009145 | purine nucleoside triphosphate biosynthetic process | 41.1765 | 7 | yes |
| GO:0009201 | ribonucleoside triphosphate biosynthetic process | 41.1765 | 7 | yes |
| GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 41.1765 | 8 | yes |
| GO:0015986 | proton motive force-driven ATP synthesis | 41.1765 | 9 | yes |
| GO:0042776 | proton motive force-driven mitochondrial ATP synthesis | 41.1765 | 10 | yes |
| GO:0043933 | protein-containing complex organization | 37.2549 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 37.2549 | 5 | yes |
| GO:0033108 | mitochondrial respiratory chain complex assembly | 35.2941 | 6 | yes |
| GO:0010257 | NADH dehydrogenase complex assembly | 33.3333 | 6 | yes |
| GO:0032981 | mitochondrial respiratory chain complex I assembly | 33.3333 | 7 | yes |
| GO:0019752 | carboxylic acid metabolic process | 25.4902 | 5 | no |
| GO:0043436 | oxoacid metabolic process | 25.4902 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ACPM_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB2_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUBB_HUMAN | [view interactions] | Low throughput | no | yes |
| NU4M_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUC2_HUMAN | [view interactions] | Low throughput | no | yes |
| NU5M_HUMAN | [view interactions] | Low throughput | no | no |
| NDUAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB1_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU1M_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA1_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB3_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUBA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUA3_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU3M_HUMAN | [view interactions] | Low throughput | no | yes |
| NU6M_HUMAN | [view interactions] | Low throughput | no | no |
| NDUC1_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUAB_HUMAN | [view interactions] | Low throughput | no | no |
| NU2M_HUMAN | [view interactions] | Low throughput | no | no |
| NU4LM_HUMAN | [view interactions] | Low throughput | no | no |
| NDUAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS5_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB5_HUMAN | [view interactions] | Low throughput | no | yes |
| DSCR9_HUMAN | [view interactions] | High throughput | no | no |
| NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLE5_HUMAN | [view interactions] | High throughput | no | no |
| RCOR3_HUMAN | [view interactions] | High throughput | no | yes |
| RECK_HUMAN | [view interactions] | High throughput | no | yes |
| MEIS2_HUMAN | [view interactions] | High throughput | no | yes |
| RBTN2_HUMAN | [view interactions] | High throughput | no | yes |
| STRA6_HUMAN | [view interactions] | High throughput | no | no |
| CBPC2_HUMAN | [view interactions] | High throughput | no | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| AN36B_HUMAN | [view interactions] | High throughput | no | no |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CREL1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
| DJC30_HUMAN | [view interactions] | High throughput | no | no |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PRRT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| MPV17_HUMAN | [view interactions] | High throughput | no | no |
| TOM7_HUMAN | [view interactions] | High throughput | no | no |
| DAF_HUMAN | [view interactions] | High throughput | no | no |
| FACE1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LTOR3_HUMAN | [view interactions] | High throughput | no | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5I_HUMAN | [view interactions] | High throughput | no | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| AT5L2_HUMAN | [view interactions] | High throughput | no | no |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUCR_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| TIM10_HUMAN | [view interactions] | High throughput | no | yes |
| QCR9_HUMAN | [view interactions] | High throughput | no | no |
| QCR6L_HUMAN | [view interactions] | High throughput | no | yes |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5E_HUMAN | [view interactions] | High throughput | no | no |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| S2512_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPR_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUA6_HUMAN | [view interactions] | High throughput | no | no |
| MAK_HUMAN | [view interactions] | High throughput | no | no |
| MLKL_HUMAN | [view interactions] | High throughput | no | no |
| ZN417_HUMAN | [view interactions] | High throughput | no | yes |
| TFAP4_HUMAN | [view interactions] | High throughput | no | yes |
| GPT2L_HUMAN | [view interactions] | High throughput | no | yes |
| ZN330_HUMAN | [view interactions] | High throughput | no | yes |
| MKRN3_HUMAN | [view interactions] | High throughput | no | yes |
| AIRIM_HUMAN | [view interactions] | High throughput | no | yes |
| ZN564_HUMAN | [view interactions] | High throughput | no | no |
| CCD24_HUMAN | [view interactions] | High throughput | no | no |
| CHIC2_HUMAN | [view interactions] | High throughput | no | no |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| CDN2D_HUMAN | [view interactions] | High throughput | no | no |
| CDA7L_HUMAN | [view interactions] | High throughput | no | yes |
| F161B_HUMAN | [view interactions] | High throughput | no | yes |
| RIPP2_HUMAN | [view interactions] | High throughput | no | no |
| RIPP1_HUMAN | [view interactions] | High throughput | no | no |
| IKBB_HUMAN | [view interactions] | High throughput | no | no |
| F90A1_HUMAN | [view interactions] | High throughput | no | no |
| ZN587_HUMAN | [view interactions] | High throughput | no | yes |
| GYS1_HUMAN | [view interactions] | High throughput | no | yes |
| IKBD_HUMAN | [view interactions] | High throughput | no | no |
| SCNM1_HUMAN | [view interactions] | High throughput | no | no |
| SPRE2_HUMAN | [view interactions] | High throughput | no | yes |
| CCNC_HUMAN | [view interactions] | High throughput | no | yes |
| KR10A_HUMAN | [view interactions] | High throughput | no | no |
| CINP_HUMAN | [view interactions] | High throughput | no | no |
| MGN2_HUMAN | [view interactions] | High throughput | no | yes |
| GEM_HUMAN | [view interactions] | High throughput | no | yes |
| SPRE1_HUMAN | [view interactions] | High throughput | no | yes |