Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

NDUA2_HUMAN

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in NDUA2_HUMAN
GO:0008324 monoatomic cation transmembrane transporter activity 36.4865 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 36.4865 4 yes
GO:0015399 primary active transmembrane transporter activity 35.1351 4 yes
GO:0022853 active monoatomic ion transmembrane transporter activity 35.1351 4 yes
GO:0015078 proton transmembrane transporter activity 33.7838 5 yes
GO:0015453 oxidoreduction-driven active transmembrane transporter activity 32.4324 5 yes
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 29.7297 4 yes
GO:0003723 RNA binding 27.0270 4 no
GO:0000166 nucleotide binding 22.9730 4 no
GO:0043168 anion binding 22.9730 4 no
GO:0017076 purine nucleotide binding 21.6216 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in NDUA2_HUMAN
GO:0022607 cellular component assembly 45.9459 4 yes
GO:0006796 phosphate-containing compound metabolic process 44.5946 4 yes
GO:0006753 nucleoside phosphate metabolic process 39.1892 4 yes
GO:0009117 nucleotide metabolic process 39.1892 5 yes
GO:0006163 purine nucleotide metabolic process 37.8378 5 yes
GO:0043933 protein-containing complex organization 37.8378 4 yes
GO:0065003 protein-containing complex assembly 37.8378 5 yes
GO:0072521 purine-containing compound metabolic process 37.8378 4 yes
GO:0009060 aerobic respiration 36.4865 6 yes
GO:0009141 nucleoside triphosphate metabolic process 36.4865 5 yes
GO:0009144 purine nucleoside triphosphate metabolic process 36.4865 6 yes
GO:0009150 purine ribonucleotide metabolic process 36.4865 6 yes
GO:0009199 ribonucleoside triphosphate metabolic process 36.4865 6 yes
GO:0009205 purine ribonucleoside triphosphate metabolic process 36.4865 7 yes
GO:0009259 ribonucleotide metabolic process 36.4865 5 yes
GO:0015980 energy derivation by oxidation of organic compounds 36.4865 4 yes
GO:0019693 ribose phosphate metabolic process 36.4865 4 yes
GO:0022900 electron transport chain 36.4865 4 yes
GO:0022904 respiratory electron transport chain 36.4865 5 yes
GO:0045333 cellular respiration 36.4865 5 yes
GO:0046034 ATP metabolic process 36.4865 7 yes
GO:0031323 regulation of cellular metabolic process 36.4865 4 no
GO:1901566 organonitrogen compound biosynthetic process 35.1351 4 yes
GO:1901362 organic cyclic compound biosynthetic process 33.7838 4 yes
GO:0019646 aerobic electron transport chain 32.4324 6 yes
GO:0034654 nucleobase-containing compound biosynthetic process 32.4324 4 yes
GO:0060255 regulation of macromolecule metabolic process 32.4324 4 no
GO:0080090 regulation of primary metabolic process 32.4324 4 no
GO:0072522 purine-containing compound biosynthetic process 31.0811 5 yes
GO:0090407 organophosphate biosynthetic process 31.0811 4 yes
GO:1901137 carbohydrate derivative biosynthetic process 31.0811 4 yes
GO:0048522 positive regulation of cellular process 31.0811 4 no
GO:0006164 purine nucleotide biosynthetic process 29.7297 6 yes
GO:0006754 ATP biosynthetic process 29.7297 8 yes
GO:0009142 nucleoside triphosphate biosynthetic process 29.7297 6 yes
GO:0009145 purine nucleoside triphosphate biosynthetic process 29.7297 7 yes
GO:0009152 purine ribonucleotide biosynthetic process 29.7297 7 yes
GO:0009165 nucleotide biosynthetic process 29.7297 6 yes
GO:0009201 ribonucleoside triphosphate biosynthetic process 29.7297 7 yes
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 29.7297 8 yes
GO:0009260 ribonucleotide biosynthetic process 29.7297 6 yes
GO:0015986 proton motive force-driven ATP synthesis 29.7297 9 yes
GO:0042776 proton motive force-driven mitochondrial ATP synthesis 29.7297 10 yes
GO:0046390 ribose phosphate biosynthetic process 29.7297 5 yes
GO:1901293 nucleoside phosphate biosynthetic process 29.7297 5 yes
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 28.3784 7 yes
GO:0009889 regulation of biosynthetic process 28.3784 4 no
GO:0010468 regulation of gene expression 28.3784 6 no
GO:0010556 regulation of macromolecule biosynthetic process 28.3784 5 no
GO:0031326 regulation of cellular biosynthetic process 28.3784 5 no
GO:0033108 mitochondrial respiratory chain complex assembly 25.6757 6 yes
GO:0006996 organelle organization 25.6757 4 no
GO:0048523 negative regulation of cellular process 25.6757 4 no
GO:0010257 NADH dehydrogenase complex assembly 24.3243 6 yes
GO:0032981 mitochondrial respiratory chain complex I assembly 24.3243 7 yes
GO:0051246 regulation of protein metabolic process 24.3243 5 no
GO:0009893 positive regulation of metabolic process 24.3243 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.9730 5 no
GO:0010604 positive regulation of macromolecule metabolic process 22.9730 5 no
GO:0010646 regulation of cell communication 22.9730 4 no
GO:0009892 negative regulation of metabolic process 21.6216 4 no
GO:0051252 regulation of RNA metabolic process 21.6216 5 no
GO:0009966 regulation of signal transduction 21.6216 4 no
GO:0010605 negative regulation of macromolecule metabolic process 20.2703 5 no
GO:0071702 organic substance transport 20.2703 4 no
GO:0006355 regulation of DNA-templated transcription 20.2703 7 no
GO:0008104 protein localization 20.2703 4 no
GO:2001141 regulation of RNA biosynthetic process 20.2703 6 no
GO:0001835 blastocyst hatching 2.7027 4 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NDUAC_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS3_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS4_HUMAN [view interactions] Low throughput no yes
NDUA9_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV1_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS6_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA6_HUMAN [view interactions] Low throughput no no
NDUA5_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUA7_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUAD_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS1_HUMAN [view entry] [view interactions] Low throughput yes no
NDUS2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUS7_HUMAN [view entry] [view interactions] Low throughput yes no
NDUS8_HUMAN [view interactions] Low throughput no yes
NDUV2_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV3_HUMAN [view interactions] Low throughput no yes
ACPM_HUMAN [view interactions] Low throughput no yes
PDK1_HUMAN [view interactions] High throughput no yes
TR61B_HUMAN [view interactions] High throughput no yes
IMP2L_HUMAN [view interactions] High throughput no yes
HTRA2_HUMAN [view interactions] High throughput no yes
IMP1L_HUMAN [view interactions] High throughput no yes
PARL_HUMAN [view interactions] High throughput no yes
FHI2B_HUMAN [view interactions] High throughput no yes
ITA4_HUMAN [view interactions] High throughput no no
FBX17_HUMAN [view interactions] High throughput no no
WNT9B_HUMAN [view interactions] High throughput no no
ZFP41_HUMAN [view interactions] High throughput no no
CISD3_HUMAN [view interactions] High throughput no yes
PML_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
PA2GD_HUMAN [view interactions] High throughput no no
F110D_HUMAN [view interactions] High throughput no no
HXA5_HUMAN [view interactions] High throughput no no
DJC30_HUMAN [view interactions] High throughput no no
HXC9_HUMAN [view interactions] High throughput no no
FAHD1_HUMAN [view interactions] High throughput no yes
MRM2_HUMAN [view interactions] High throughput no yes
TET5B_HUMAN [view interactions] High throughput no no
EMP3_HUMAN [view interactions] High throughput no no
SPY2_HUMAN [view interactions] High throughput no yes
ECSIT_HUMAN [view interactions] High throughput no yes
DRB1_HUMAN [view interactions] High throughput no no
TECTB_HUMAN [view interactions] High throughput no no
NDUA1_HUMAN [view interactions] High throughput no yes
WN10B_HUMAN [view interactions] High throughput no yes
TRMO_HUMAN [view interactions] High throughput no no
ACSM5_HUMAN [view interactions] High throughput no yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
FOXA1_HUMAN [view interactions] High throughput no no
MYCN_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
BTF3_HUMAN [view interactions] High throughput no yes
CN178_HUMAN [view interactions] High throughput no no
IF4G2_HUMAN [view entry] [view interactions] High throughput yes yes
LEO1_HUMAN [view interactions] High throughput no yes
NAA25_HUMAN [view interactions] High throughput no yes
NDUA2_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD6_HUMAN [view interactions] High throughput no yes
SAE2_HUMAN [view interactions] High throughput no yes
SKI8_HUMAN [view interactions] High throughput no yes
YTDC1_HUMAN [view interactions] High throughput no yes
RIT1_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
QCR8_HUMAN [view interactions] High throughput no yes
MRP2_HUMAN [view interactions] High throughput no no
LTOR3_HUMAN [view interactions] High throughput no yes
RL38_HUMAN [view entry] [view interactions] High throughput yes yes
TIM44_HUMAN [view interactions] High throughput no yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
UBE4B_HUMAN [view interactions] High throughput no yes
THIK_HUMAN [view entry] [view interactions] High throughput yes yes
SUGP1_HUMAN [view interactions] High throughput no yes
SPRE_HUMAN [view interactions] High throughput no yes
PAF15_HUMAN [view interactions] High throughput no no
RBM27_HUMAN [view interactions] High throughput no yes
ZC11A_HUMAN [view interactions] High throughput no yes
ACAD9_HUMAN [view interactions] High throughput no yes
SNX3_HUMAN [view entry] [view interactions] High throughput yes no
SOSB1_HUMAN [view interactions] High throughput no yes
RU1C_HUMAN [view interactions] High throughput no yes
ABCBA_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view entry] [view interactions] High throughput yes yes
ILF3_HUMAN [view interactions] High throughput no yes
RM43_HUMAN [view interactions] High throughput no no
RFX5_HUMAN [view interactions] High throughput no yes
SBDS_HUMAN [view interactions] High throughput no yes
CDV3_HUMAN [view interactions] High throughput no no
RRFM_HUMAN [view interactions] High throughput no yes
PIN4_HUMAN [view interactions] High throughput no yes
CPT1A_HUMAN [view entry] [view interactions] High throughput yes yes
ECI2_HUMAN [view entry] [view interactions] High throughput yes yes
TBL2_HUMAN [view interactions] High throughput no no
P66B_HUMAN [view interactions] High throughput no yes
5NTD_HUMAN [view entry] [view interactions] High throughput yes yes
DHX30_HUMAN [view entry] [view interactions] High throughput yes yes
OLA1_HUMAN [view entry] [view interactions] High throughput yes yes
ICT1_HUMAN [view interactions] High throughput no yes
VA0D1_HUMAN [view entry] [view interactions] High throughput yes yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
AT1B3_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
MTCH2_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
SDHB_HUMAN [view interactions] High throughput no yes
TOM40_HUMAN [view interactions] High throughput no yes
PHB2_HUMAN [view entry] [view interactions] High throughput yes yes
ARMX2_HUMAN [view interactions] High throughput no yes
LRC59_HUMAN [view entry] [view interactions] High throughput yes yes
TIM16_HUMAN [view entry] [view interactions] High throughput yes no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5H_HUMAN [view interactions] High throughput no yes
ATP5E_HUMAN [view interactions] High throughput no no
ATP5I_HUMAN [view interactions] High throughput no yes
ATPK_HUMAN [view interactions] High throughput no yes
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
COX6C_HUMAN [view entry] [view interactions] High throughput yes yes
CX7A2_HUMAN [view interactions] High throughput no no
NDUB6_HUMAN [view entry] [view interactions] High throughput yes yes
NDUCR_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
QCR6L_HUMAN [view interactions] High throughput no yes
QCR6_HUMAN [view interactions] High throughput no yes
NDUA3_HUMAN [view interactions] High throughput no yes
NDUB4_HUMAN [view entry] [view interactions] High throughput yes yes
AT5L2_HUMAN [view interactions] High throughput no no
ATP5L_HUMAN [view interactions] High throughput no yes
MRM1_HUMAN [view interactions] High throughput no no
GRSF1_HUMAN [view interactions] High throughput no yes
AUHM_HUMAN [view entry] [view interactions] High throughput yes yes
MTRFR_HUMAN [view interactions] High throughput no yes
CQ080_HUMAN [view interactions] High throughput no yes
C1QBP_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no no
MRES1_HUMAN [view interactions] High throughput no yes
CH082_HUMAN [view interactions] High throughput no yes
MCUR1_HUMAN [view interactions] High throughput no no
CC90B_HUMAN [view interactions] High throughput no yes
CHCH1_HUMAN [view interactions] High throughput no yes
COX15_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
DDX28_HUMAN [view interactions] High throughput no yes
FAKD2_HUMAN [view interactions] High throughput no no
FAKD3_HUMAN [view interactions] High throughput no yes
FAKD5_HUMAN [view interactions] High throughput no yes
EFGM_HUMAN [view interactions] High throughput no yes
RRF2M_HUMAN [view interactions] High throughput no yes
HINT2_HUMAN [view interactions] High throughput no yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
MCU_HUMAN [view interactions] High throughput no yes
MCUB_HUMAN [view interactions] High throughput no no
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
MET15_HUMAN [view interactions] High throughput no no
MET17_HUMAN [view interactions] High throughput no yes
RM11_HUMAN [view interactions] High throughput no yes
RT12_HUMAN [view interactions] High throughput no yes
RT26_HUMAN [view interactions] High throughput no yes
MTEF3_HUMAN [view interactions] High throughput no no
FMT_HUMAN [view interactions] High throughput no yes
MTG1_HUMAN [view interactions] High throughput no yes
MTG2_HUMAN [view interactions] High throughput no yes
IF2M_HUMAN [view interactions] High throughput no yes
IF3M_HUMAN [view interactions] High throughput no yes
RF1M_HUMAN [view interactions] High throughput no yes
RF1ML_HUMAN [view interactions] High throughput no yes
NGRN_HUMAN [view interactions] High throughput no yes
OTC_HUMAN [view interactions] High throughput no no
MPPA_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
RUSD3_HUMAN [view interactions] High throughput no yes
RUSD4_HUMAN [view interactions] High throughput no yes
SLIRP_HUMAN [view interactions] High throughput no yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
SURF1_HUMAN [view interactions] High throughput no yes
TACO1_HUMAN [view interactions] High throughput no yes
FAKD4_HUMAN [view interactions] High throughput no yes
TEFM_HUMAN [view interactions] High throughput no no
TFAM_HUMAN [view entry] [view interactions] High throughput yes yes
TMM70_HUMAN [view interactions] High throughput no yes
TRUB2_HUMAN [view interactions] High throughput no yes
EFTS_HUMAN [view interactions] High throughput no no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
VWA8_HUMAN [view interactions] High throughput no yes
EXD2_HUMAN [view interactions] High throughput no yes
CLPP_HUMAN [view interactions] High throughput no yes
DNJA3_HUMAN [view entry] [view interactions] High throughput yes yes
DJC15_HUMAN [view interactions] High throughput no no
TIM14_HUMAN [view entry] [view interactions] High throughput yes yes
DJC28_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
NUP35_HUMAN [view interactions] High throughput no yes
ETFB_HUMAN [view entry] [view interactions] High throughput yes yes
NSG2_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS5_HUMAN [view interactions] High throughput no yes
NDUAB_HUMAN [view interactions] High throughput no no
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RMD3_HUMAN [view entry] [view interactions] High throughput yes yes
TMED2_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
EMC5_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
KSR1_HUMAN [view interactions] High throughput no yes
NMES1_HUMAN [view interactions] High throughput no no
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
ATPA_HUMAN [view interactions] High throughput no yes
SPT20_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
HSC20_HUMAN [view interactions] High throughput no yes
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
CAV3_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
NDUAA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB3_HUMAN [view interactions] High throughput no yes
NDUB5_HUMAN [view interactions] High throughput no yes
NDUB7_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB8_HUMAN [view entry] [view interactions] High throughput yes yes
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUBB_HUMAN [view interactions] High throughput no yes
NDUC2_HUMAN [view interactions] High throughput no yes
NU1M_HUMAN [view interactions] High throughput no yes
NU4M_HUMAN [view interactions] High throughput no yes
AKIP_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
COX14_HUMAN [view interactions] High throughput no yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes