NDUBA_HUMAN
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in NDUBA_HUMAN |
---|---|---|---|---|
GO:0015399 | primary active transmembrane transporter activity | 32.2917 | 4 | yes |
GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 31.2500 | 5 | yes |
GO:0046872 | metal ion binding | 31.2500 | 4 | no |
GO:0003954 | NADH dehydrogenase activity | 25.0000 | 4 | yes |
GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | 23.9583 | 5 | yes |
GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 23.9583 | 4 | yes |
GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 23.9583 | 4 | yes |
GO:0050136 | NADH dehydrogenase (quinone) activity | 23.9583 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in NDUBA_HUMAN |
---|---|---|---|---|
GO:0009060 | aerobic respiration | 35.4167 | 6 | yes |
GO:0015980 | energy derivation by oxidation of organic compounds | 35.4167 | 4 | yes |
GO:0022900 | electron transport chain | 35.4167 | 4 | yes |
GO:0022904 | respiratory electron transport chain | 35.4167 | 5 | yes |
GO:0045333 | cellular respiration | 35.4167 | 5 | yes |
GO:0019646 | aerobic electron transport chain | 32.2917 | 6 | yes |
GO:0022607 | cellular component assembly | 31.2500 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 30.2083 | 4 | no |
GO:0043933 | protein-containing complex organization | 25.0000 | 4 | yes |
GO:0065003 | protein-containing complex assembly | 25.0000 | 5 | yes |
GO:0031323 | regulation of cellular metabolic process | 23.9583 | 4 | no |
GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | 22.9167 | 7 | yes |
GO:0009893 | positive regulation of metabolic process | 22.9167 | 4 | no |
GO:0048523 | negative regulation of cellular process | 22.9167 | 4 | no |
GO:0006996 | organelle organization | 21.8750 | 4 | no |
GO:0033108 | mitochondrial respiratory chain complex assembly | 20.8333 | 6 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 20.8333 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 20.8333 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 20.8333 | 4 | no |
GO:0019752 | carboxylic acid metabolic process | 20.8333 | 5 | no |
GO:0043436 | oxoacid metabolic process | 20.8333 | 4 | no |
GO:0010257 | NADH dehydrogenase complex assembly | 19.7917 | 6 | yes |
GO:0032981 | mitochondrial respiratory chain complex I assembly | 19.7917 | 7 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in NDUBA_HUMAN |
---|---|---|---|---|
DOID:0080000 | muscular disease | 2.0833 | 3 | no |
DOID:3191 | nemaline myopathy | 2.0833 | 7 | no |
DOID:422 | congenital structural myopathy | 2.0833 | 6 | no |
DOID:423 | myopathy | 2.0833 | 5 | no |
DOID:66 | muscle tissue disease | 2.0833 | 4 | no |
DOID:440 | neuromuscular disease | 2.0833 | 5 | no |
DOID:574 | peripheral nervous system disease | 2.0833 | 3 | no |
DOID:870 | neuropathy | 2.0833 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
NDUBB_HUMAN | [view interactions] | Low throughput | no | yes |
NDUC2_HUMAN | [view interactions] | Low throughput | no | yes |
NDUAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUB3_HUMAN | [view interactions] | Low throughput | no | yes |
NDUA1_HUMAN | [view interactions] | Low throughput | no | yes |
MYC_HUMAN | [view interactions] | Low throughput | no | yes |
NDUB9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUB7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUB1_HUMAN | [view interactions] | Low throughput | no | yes |
NDUA8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUB6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NDUA3_HUMAN | [view interactions] | Low throughput | no | yes |
NDUB2_HUMAN | [view interactions] | Low throughput | no | yes |
NU6M_HUMAN | [view interactions] | Low throughput | no | no |
NDUC1_HUMAN | [view interactions] | Low throughput | no | yes |
NDUAB_HUMAN | [view interactions] | Low throughput | no | no |
NU2M_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
NU4LM_HUMAN | [view interactions] | Low throughput | no | no |
NU1M_HUMAN | [view interactions] | Low throughput | no | yes |
NDUB8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NU4M_HUMAN | [view interactions] | Low throughput | no | yes |
NU5M_HUMAN | [view interactions] | Low throughput | no | no |
NU3M_HUMAN | [view interactions] | Low throughput | no | yes |
NDUS5_HUMAN | [view interactions] | Low throughput | no | yes |
NDUB5_HUMAN | [view interactions] | Low throughput | no | yes |
ACPM_HUMAN | [view interactions] | Low throughput | no | yes |
EGLN3_HUMAN | [view interactions] | High throughput | no | no |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
FXRD1_HUMAN | [view interactions] | High throughput | no | no |
TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H4_HUMAN | [view interactions] | High throughput | no | yes |
S15A3_HUMAN | [view interactions] | High throughput | no | yes |
UN93B_HUMAN | [view interactions] | High throughput | no | yes |
TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LMBRL_HUMAN | [view interactions] | High throughput | no | no |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
KI20A_HUMAN | [view interactions] | High throughput | no | yes |
CFAD_HUMAN | [view interactions] | High throughput | no | no |
FNDC5_HUMAN | [view interactions] | High throughput | no | no |
DNJB8_HUMAN | [view interactions] | High throughput | no | no |
DDX58_HUMAN | [view interactions] | High throughput | no | yes |
NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
DJC30_HUMAN | [view interactions] | High throughput | no | no |
CCNF_HUMAN | [view interactions] | High throughput | no | no |
CBX1_HUMAN | [view interactions] | High throughput | no | yes |
MTMR1_HUMAN | [view interactions] | High throughput | no | yes |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
TMED2_HUMAN | [view interactions] | High throughput | no | yes |
NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
YBOX3_HUMAN | [view interactions] | High throughput | no | yes |
MARC1_HUMAN | [view interactions] | High throughput | no | yes |
UQCC3_HUMAN | [view interactions] | High throughput | no | yes |
FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RM13_HUMAN | [view interactions] | High throughput | no | yes |
ATPO_HUMAN | [view interactions] | High throughput | no | yes |
BAP31_HUMAN | [view interactions] | High throughput | no | yes |
RT07_HUMAN | [view interactions] | High throughput | no | yes |
MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COX7C_HUMAN | [view interactions] | High throughput | no | yes |
COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COA3_HUMAN | [view interactions] | High throughput | no | yes |
ATPA_HUMAN | [view interactions] | High throughput | no | yes |
SCMC1_HUMAN | [view interactions] | High throughput | no | no |
ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
AL1B1_HUMAN | [view interactions] | High throughput | no | yes |
NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATPB_HUMAN | [view interactions] | High throughput | no | yes |
ADAS_HUMAN | [view interactions] | High throughput | no | yes |
RCN2_HUMAN | [view interactions] | High throughput | no | yes |
ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
COX5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MCCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPRC_HUMAN | [view interactions] | High throughput | no | yes |
VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
ATPK_HUMAN | [view interactions] | High throughput | no | yes |
COQ9_HUMAN | [view interactions] | High throughput | no | yes |
CX6A1_HUMAN | [view interactions] | High throughput | no | yes |
HCDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SODM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
QCR6L_HUMAN | [view interactions] | High throughput | no | yes |
QCR6_HUMAN | [view interactions] | High throughput | no | yes |
SUCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATPG_HUMAN | [view interactions] | High throughput | no | yes |
AT5L2_HUMAN | [view interactions] | High throughput | no | no |
ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
BOLA3_HUMAN | [view interactions] | High throughput | no | yes |
CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CNTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HINT2_HUMAN | [view interactions] | High throughput | no | yes |
IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEGR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SDHA_HUMAN | [view interactions] | High throughput | no | yes |
SDHB_HUMAN | [view interactions] | High throughput | no | yes |
SNP25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
QCR9_HUMAN | [view interactions] | High throughput | no | no |
UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATPMK_HUMAN | [view interactions] | High throughput | no | no |
ATPD_HUMAN | [view interactions] | High throughput | no | yes |
ATP5E_HUMAN | [view interactions] | High throughput | no | no |
ATP5I_HUMAN | [view interactions] | High throughput | no | yes |
COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CX7A2_HUMAN | [view interactions] | High throughput | no | no |
ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBN2_HUMAN | [view interactions] | High throughput | no | no |
SUCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OPTN_HUMAN | [view interactions] | High throughput | no | yes |
GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
GAL3B_HUMAN | [view interactions] | High throughput | no | yes |
MCUR1_HUMAN | [view interactions] | High throughput | no | no |
CC90B_HUMAN | [view interactions] | High throughput | no | yes |
DBLOH_HUMAN | [view interactions] | High throughput | no | no |
MCUB_HUMAN | [view interactions] | High throughput | no | no |
MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RMND1_HUMAN | [view interactions] | High throughput | no | yes |
CMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S2551_HUMAN | [view interactions] | High throughput | no | no |
SURF1_HUMAN | [view interactions] | High throughput | no | yes |
TMM70_HUMAN | [view interactions] | High throughput | no | yes |
DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DJC15_HUMAN | [view interactions] | High throughput | no | no |
SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U2D2L_HUMAN | [view interactions] | High throughput | no | no |
DUX4C_HUMAN | [view interactions] | High throughput | no | no |
5HT2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MK06_HUMAN | [view interactions] | High throughput | no | yes |
RIPK4_HUMAN | [view interactions] | High throughput | no | no |
NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUF3_HUMAN | [view interactions] | High throughput | no | yes |
TIDC1_HUMAN | [view interactions] | High throughput | no | yes |
NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NMES1_HUMAN | [view interactions] | High throughput | no | no |
NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUF4_HUMAN | [view interactions] | High throughput | no | yes |
MIA40_HUMAN | [view interactions] | High throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA6_HUMAN | [view interactions] | High throughput | no | no |
HSC20_HUMAN | [view interactions] | High throughput | no | yes |
CAV3_HUMAN | [view interactions] | High throughput | no | no |
RYBP_HUMAN | [view interactions] | High throughput | no | no |
CNDD3_HUMAN | [view interactions] | High throughput | no | no |
FAM9B_HUMAN | [view interactions] | High throughput | no | no |
HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RPAC1_HUMAN | [view interactions] | High throughput | no | no |
LA_HUMAN | [view interactions] | High throughput | no | yes |
T185A_HUMAN | [view interactions] | High throughput | no | no |
ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
LACTB_HUMAN | [view interactions] | High throughput | no | yes |
OMA1_HUMAN | [view interactions] | High throughput | no | no |
PARL_HUMAN | [view interactions] | High throughput | no | yes |
FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
XRN1_HUMAN | [view interactions] | High throughput | no | yes |
DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
PTN22_HUMAN | [view interactions] | High throughput | no | yes |
LGUL_HUMAN | [view interactions] | Computational | no | yes |
NDUCR_HUMAN | [view interactions] | Computational | no | yes |
CX6A2_HUMAN | [view interactions] | Computational | no | no |
GLRX5_HUMAN | [view interactions] | Computational | no | yes |
C560_HUMAN | [view interactions] | Computational | no | no |
COX5B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PT100_HUMAN | [view interactions] | Computational | no | no |
QCR7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RM27_HUMAN | [view interactions] | Computational | no | yes |
COX42_HUMAN | [view interactions] | Computational | no | no |
CX6B2_HUMAN | [view interactions] | Computational | no | no |
COA6_HUMAN | [view interactions] | Computational | no | yes |
QCR8_HUMAN | [view interactions] | Computational | no | yes |
MIC19_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CYB_HUMAN | [view interactions] | Computational | no | yes |
QCR10_HUMAN | [view interactions] | Computational | no | no |
MIC27_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ATP5J_HUMAN | [view interactions] | Computational | no | yes |
DHSD_HUMAN | [view interactions] | Computational | no | yes |
CIA30_HUMAN | [view interactions] | Computational | no | yes |