NDUBA_HUMAN
Evidence for PS localization
Functions
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NDUBA_HUMAN |
|---|---|---|---|---|
| GO:0008324 | monoatomic cation transmembrane transporter activity | 36.1702 | 4 | yes |
| GO:0022890 | inorganic cation transmembrane transporter activity | 36.1702 | 4 | yes |
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 32.9787 | 4 | yes |
| GO:0043169 | cation binding | 32.9787 | 4 | no |
| GO:0015078 | proton transmembrane transporter activity | 31.9149 | 5 | yes |
| GO:0046872 | metal ion binding | 30.8511 | 5 | no |
| GO:0015399 | primary active transmembrane transporter activity | 29.7872 | 4 | yes |
| GO:0015453 | oxidoreduction-driven active transmembrane transporter activity | 28.7234 | 5 | yes |
| GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 22.3404 | 4 | yes |
| GO:0000166 | nucleotide binding | 20.2128 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NDUBA_HUMAN |
|---|---|---|---|---|
| GO:0006796 | phosphate-containing compound metabolic process | 38.2979 | 4 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 37.2340 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 37.2340 | 5 | yes |
| GO:0006163 | purine nucleotide metabolic process | 36.1702 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 36.1702 | 4 | yes |
| GO:0009060 | aerobic respiration | 35.1064 | 6 | yes |
| GO:0015980 | energy derivation by oxidation of organic compounds | 35.1064 | 4 | yes |
| GO:0022900 | electron transport chain | 35.1064 | 4 | yes |
| GO:0022904 | respiratory electron transport chain | 35.1064 | 5 | yes |
| GO:0045333 | cellular respiration | 35.1064 | 5 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 34.0426 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 34.0426 | 5 | yes |
| GO:0019693 | ribose phosphate metabolic process | 34.0426 | 4 | yes |
| GO:0022607 | cellular component assembly | 32.9787 | 4 | yes |
| GO:0019646 | aerobic electron transport chain | 31.9149 | 6 | yes |
| GO:0048522 | positive regulation of cellular process | 29.7872 | 4 | no |
| GO:0043933 | protein-containing complex organization | 28.7234 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 28.7234 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 27.6596 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 27.6596 | 4 | no |
| GO:0009141 | nucleoside triphosphate metabolic process | 26.5957 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 26.5957 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 26.5957 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 26.5957 | 7 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 26.5957 | 4 | yes |
| GO:0046034 | ATP metabolic process | 26.5957 | 7 | yes |
| GO:0065003 | protein-containing complex assembly | 26.5957 | 5 | yes |
| GO:0006164 | purine nucleotide biosynthetic process | 25.5319 | 6 | yes |
| GO:0009152 | purine ribonucleotide biosynthetic process | 25.5319 | 7 | yes |
| GO:0009165 | nucleotide biosynthetic process | 25.5319 | 6 | yes |
| GO:0009260 | ribonucleotide biosynthetic process | 25.5319 | 6 | yes |
| GO:0046390 | ribose phosphate biosynthetic process | 25.5319 | 5 | yes |
| GO:0072522 | purine-containing compound biosynthetic process | 25.5319 | 5 | yes |
| GO:0090407 | organophosphate biosynthetic process | 25.5319 | 4 | yes |
| GO:1901137 | carbohydrate derivative biosynthetic process | 25.5319 | 4 | yes |
| GO:1901293 | nucleoside phosphate biosynthetic process | 25.5319 | 5 | yes |
| GO:0006996 | organelle organization | 24.4681 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 24.4681 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 24.4681 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 23.4043 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 23.4043 | 4 | no |
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | 22.3404 | 7 | yes |
| GO:0006754 | ATP biosynthetic process | 22.3404 | 8 | yes |
| GO:0009142 | nucleoside triphosphate biosynthetic process | 22.3404 | 6 | yes |
| GO:0009145 | purine nucleoside triphosphate biosynthetic process | 22.3404 | 7 | yes |
| GO:0009201 | ribonucleoside triphosphate biosynthetic process | 22.3404 | 7 | yes |
| GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 22.3404 | 8 | yes |
| GO:0015986 | proton motive force-driven ATP synthesis | 22.3404 | 9 | yes |
| GO:0042776 | proton motive force-driven mitochondrial ATP synthesis | 22.3404 | 10 | yes |
| GO:0019752 | carboxylic acid metabolic process | 22.3404 | 5 | no |
| GO:0043436 | oxoacid metabolic process | 22.3404 | 4 | no |
| GO:0010646 | regulation of cell communication | 22.3404 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 21.2766 | 4 | no |
| GO:0033108 | mitochondrial respiratory chain complex assembly | 20.2128 | 6 | yes |
| GO:0010257 | NADH dehydrogenase complex assembly | 19.1489 | 6 | yes |
| GO:0032981 | mitochondrial respiratory chain complex I assembly | 19.1489 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NDUB1_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU3M_HUMAN | [view interactions] | Low throughput | no | yes |
| NU6M_HUMAN | [view interactions] | Low throughput | no | no |
| NDUC1_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUAB_HUMAN | [view interactions] | Low throughput | no | no |
| NDUA3_HUMAN | [view interactions] | Low throughput | no | yes |
| NU2M_HUMAN | [view interactions] | Low throughput | no | no |
| NU4LM_HUMAN | [view interactions] | Low throughput | no | no |
| NDUB8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NU4M_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB2_HUMAN | [view interactions] | Low throughput | no | yes |
| NU1M_HUMAN | [view interactions] | Low throughput | no | yes |
| NU5M_HUMAN | [view interactions] | Low throughput | no | no |
| NDUS5_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB5_HUMAN | [view interactions] | Low throughput | no | yes |
| ACPM_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUBB_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUC2_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB3_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUA1_HUMAN | [view interactions] | Low throughput | no | yes |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| NDUB9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDUB7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX7C_HUMAN | [view interactions] | High throughput | no | yes |
| COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COA3_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| SCMC1_HUMAN | [view interactions] | High throughput | no | no |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| AL1B1_HUMAN | [view interactions] | High throughput | no | yes |
| NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| ADAS_HUMAN | [view interactions] | High throughput | no | yes |
| RCN2_HUMAN | [view interactions] | High throughput | no | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COX5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MCCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRC_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| CX6A1_HUMAN | [view interactions] | High throughput | no | yes |
| HCDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SODM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR6L_HUMAN | [view interactions] | High throughput | no | yes |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| SUCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| AT5L2_HUMAN | [view interactions] | High throughput | no | no |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| BOLA3_HUMAN | [view interactions] | High throughput | no | yes |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
| GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEGR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| SNP25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| QCR9_HUMAN | [view interactions] | High throughput | no | no |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5E_HUMAN | [view interactions] | High throughput | no | no |
| ATP5I_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX7A2_HUMAN | [view interactions] | High throughput | no | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBN2_HUMAN | [view interactions] | High throughput | no | no |
| SUCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | no |
| MCUR1_HUMAN | [view interactions] | High throughput | no | no |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | High throughput | no | no |
| MCUB_HUMAN | [view interactions] | High throughput | no | no |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMND1_HUMAN | [view interactions] | High throughput | no | yes |
| S2512_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2551_HUMAN | [view interactions] | High throughput | no | no |
| SURF1_HUMAN | [view interactions] | High throughput | no | yes |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC15_HUMAN | [view interactions] | High throughput | no | no |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U2D2L_HUMAN | [view interactions] | High throughput | no | no |
| DUX4C_HUMAN | [view interactions] | High throughput | no | no |
| 5HT2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUF3_HUMAN | [view interactions] | High throughput | no | yes |
| TIDC1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| NDUF4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| SIM26_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA6_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| CNDD3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| FAM9B_HUMAN | [view interactions] | High throughput | no | no |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPAC1_HUMAN | [view interactions] | High throughput | no | no |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| T185A_HUMAN | [view interactions] | High throughput | no | no |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| OMA1_HUMAN | [view interactions] | High throughput | no | no |
| PARL_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XRN1_HUMAN | [view interactions] | High throughput | no | yes |
| DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
| RN181_HUMAN | [view interactions] | High throughput | no | no |
| PTN22_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| FXRD1_HUMAN | [view interactions] | High throughput | no | no |
| TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| DNJB8_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV3_HUMAN | [view interactions] | High throughput | no | yes |
| DJC30_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR1_HUMAN | [view interactions] | High throughput | no | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| PRRT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YBOX3_HUMAN | [view interactions] | High throughput | no | yes |
| MARC1_HUMAN | [view interactions] | High throughput | no | yes |
| UQCC3_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM13_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| RT07_HUMAN | [view interactions] | High throughput | no | yes |
| S25A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |